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<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU27</accession>
    <name>D3PU27_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1264</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016544.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1264"/>
    <dbReference type="EnsemblBacteria" id="ADD40973">
        <property type="protein sequence ID" value="ADD40973"/>
        <property type="gene ID" value="Snas_1264"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1264"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_0_1_11"/>
    <dbReference type="OMA" id="QQCYYVA"/>
    <dbReference type="OrthoDB" id="1844486at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="161" mass="18099" checksum="A0E1E1FFDD637B0E" modified="2010-04-20" version="1">MPSSLVLDEIDHHLLDLLQHDADRTLREFGDDVGLTPSAVQRRIARYRKAGLISRQVAILDPHQLGPTVLASVMITLVHESLEHHKQFTDRMRATPEVQQCYLIAGPCDYLVLLAANSPRHCSQLGNRLFKSDDNIKRYETSMVFDTIKAGLTIPLTDRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU41</accession>
    <name>D3PU41_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH-quinone oxidoreductase, E subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1278</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016558.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1278"/>
    <dbReference type="EnsemblBacteria" id="ADD40987">
        <property type="protein sequence ID" value="ADD40987"/>
        <property type="gene ID" value="Snas_1278"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1278"/>
    <dbReference type="eggNOG" id="COG1905">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054537_1_0_11"/>
    <dbReference type="OMA" id="QVGVCTN"/>
    <dbReference type="OrthoDB" id="1206880at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01958">
        <property type="entry name" value="nuoE_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000216-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="230" mass="25022" checksum="DC6465CEFF292E51" modified="2010-04-20" version="1">MAYTEEFRAQAREIMERYPEGKQRSALLPMLHLVQSQDGYITQDGIAFCAEMIGITKAQVAAVSTFYTMYKREPTGDYLVSVCTNTLCDVMGGQKVFDALREYLGVDHDETTGDGKITLEHAECLAACDYAPVMTVNYEFFDKTNPDEAVQLAKNLRNGERPTPTRGAPLCTLKEMSRQLAGWAEDREAGLAGNAAADPTLAGARLAADAGITAPPVDPEVSLVKKEDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUA9</accession>
    <name>D3PUA9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1347"/>
    <dbReference type="EnsemblBacteria" id="ADD41055">
        <property type="protein sequence ID" value="ADD41055"/>
        <property type="gene ID" value="Snas_1347"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1347"/>
    <dbReference type="HOGENOM" id="CLU_3066459_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="53" mass="5468" checksum="07C6B59E4943F6F5" modified="2010-04-20" version="1">MNIDVPSRCPHDVDSDPVAPPPESRQWDVSFAATAGLGGAIADPATPPEPEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUM3</accession>
    <name>D3PUM3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmB</name>
        <name evidence="6" type="ordered locus">Snas_3372</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018607.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3372"/>
    <dbReference type="EnsemblBacteria" id="ADD43036">
        <property type="protein sequence ID" value="ADD43036"/>
        <property type="gene ID" value="Snas_3372"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3372"/>
    <dbReference type="eggNOG" id="COG0227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064548_3_1_11"/>
    <dbReference type="OMA" id="FEPNLHT"/>
    <dbReference type="OrthoDB" id="2062238at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribo_L28/L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribo_L28/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_L28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="PTHR13528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="78" mass="8965" checksum="D20533C6A71B7969" modified="2010-04-20" version="1">MTRRCDVTGAGPGFGNSVSHSAHRTRRRWNPNLQRRRYWLPSQQRWIRLRVSAKAIRTIDRDGIEAVIARVRAAGGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUX1</accession>
    <name>D3PUX1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5362</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5362"/>
    <dbReference type="EnsemblBacteria" id="ADD44995">
        <property type="protein sequence ID" value="ADD44995"/>
        <property type="gene ID" value="Snas_5362"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5362"/>
    <dbReference type="HOGENOM" id="CLU_2195328_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="108" mass="11323" checksum="15DE3E09C1257122" modified="2010-04-20" version="1">MNVKVNDADLHDAATAPSQLPALIGCAKDLAAMTAEAQGGTPHLGGSAHALYTLASYMNDAIIRNHKSVAAGLEKAAIDYKNADDEGDREVSKALRLLPGDLRRKAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV14</accession>
    <name>D3PV14_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020609.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5406"/>
    <dbReference type="EnsemblBacteria" id="ADD45038">
        <property type="protein sequence ID" value="ADD45038"/>
        <property type="gene ID" value="Snas_5406"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5406"/>
    <dbReference type="HOGENOM" id="CLU_131550_3_0_11"/>
    <dbReference type="OrthoDB" id="1996962at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="1">
        <location>
            <begin position="5"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="65" mass="7093" checksum="29655D51E1857FD6" modified="2010-04-20" version="1">MVDPRWRKSSRSSGSNSSQCVEVANLIPAIGVRDSKHLDSGVLTVPHNDWIGLVASVKSNQFDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVB3</accession>
    <name>D3PVB3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF43 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016737.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1462"/>
    <dbReference type="EnsemblBacteria" id="ADD41166">
        <property type="protein sequence ID" value="ADD41166"/>
        <property type="gene ID" value="Snas_1462"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1462"/>
    <dbReference type="eggNOG" id="COG1568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042160_0_0_11"/>
    <dbReference type="OrthoDB" id="529167at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002723">
        <property type="entry name" value="BpsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01861">
        <property type="entry name" value="DUF43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF43" evidence="1">
        <location>
            <begin position="128"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="402" mass="42846" checksum="45A4EDDD9668857B" modified="2010-04-20" version="1">MTCADSAASTPDRSRVIDRRDVNEIATQVARAVDLAEGAWGVVDVLRAIARHEPVAVRELSRHVELPVPIVAAIGNELRKRGIVDTQRPVRLTEVGRMVMGTETWLDSGDCPTCAGRGITVPAELDELADELSGVAERMPGARMELDQAHCTVDTKLRRVMLLSKLGVLAKPMIFIGDDDLTSLAVAMVAKSVGLPIGPMTVVDVDEALLDYIAAQARELGTDLTAVHHDATRPLPEALREGFAVALTDPPYTLAGAELFLSRAVSALEPRPGQHLLFSFGGRRPAETVAVQALIAGMGLAVRSLVPNFNEYLGAGILGGTSHLYHLRTVDGAAPSIDGDFDGPLYTADNRTESVRGFRCAACKTVQPVGPGQRFARIAELKAAGCPECGATTFRPLPLTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVE6</accession>
    <name>D3PVE6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DEAD/DEAH box helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3396</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018631.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3396"/>
    <dbReference type="EnsemblBacteria" id="ADD43060">
        <property type="protein sequence ID" value="ADD43060"/>
        <property type="gene ID" value="Snas_3396"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3396"/>
    <dbReference type="eggNOG" id="COG4581">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017075_0_0_11"/>
    <dbReference type="OMA" id="DEFHFYA"/>
    <dbReference type="OrthoDB" id="66530at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021904">
        <property type="entry name" value="DUF3516"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12029">
        <property type="entry name" value="DUF3516"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="39"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="215"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="832" mass="91990" checksum="D187C45D6470A85C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVU7</accession>
    <name>D3PVU7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type IV secretory pathway VirD4 protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5436</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VirD4/TraG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020639.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5436"/>
    <dbReference type="EnsemblBacteria" id="ADD45068">
        <property type="protein sequence ID" value="ADD45068"/>
        <property type="gene ID" value="Snas_5436"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5436"/>
    <dbReference type="eggNOG" id="COG3505">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029028_2_0_11"/>
    <dbReference type="OMA" id="FRWTLDP"/>
    <dbReference type="OrthoDB" id="246216at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003688">
        <property type="entry name" value="TraG/VirD4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02534">
        <property type="entry name" value="T4SS-DNA_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="588"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="611" mass="65483" checksum="8674076D67DB3F1A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWA5</accession>
    <name>D3PWA5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1559</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016833.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1559"/>
    <dbReference type="MEROPS" id="S08.050"/>
    <dbReference type="EnsemblBacteria" id="ADD41262">
        <property type="protein sequence ID" value="ADD41262"/>
        <property type="gene ID" value="Snas_1559"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1559"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4935">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_1_7_11"/>
    <dbReference type="OMA" id="RIRWGTN"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049504" evidence="5">
        <location>
            <begin position="33"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="6">
        <location>
            <begin position="397"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="514" mass="51202" checksum="8AF4E41857745415" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWC4</accession>
    <name>D3PWC4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016852.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1578"/>
    <dbReference type="EnsemblBacteria" id="ADD41281">
        <property type="protein sequence ID" value="ADD41281"/>
        <property type="gene ID" value="Snas_1578"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1578"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_5_0_11"/>
    <dbReference type="OMA" id="IGHADFM"/>
    <dbReference type="OrthoDB" id="846433at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="31824" checksum="63F779AD0C38B146" modified="2010-04-20" version="1">MDLALLRTFLAVYRAGSLTRAVPLLGLSQPTITAQLKTLESALDKKLFERLPRGVAPTPVAEELARRVAPHIDALTAIGDRGVDAHDPFSTPVHLAGPGELITTRVLPSLADLVGAGLRLRVSLGLSDDLLSGLAAGTYDLVISTIRPRARAITATPLTDEEFVLVAAPGWAERIDADLLSTDPLAALRNVPLVSYAEDLPVIRRYWRTSFGVRPKGSAVVVVPDLRGVLAATVSGCGITVLPRYLCVGELAEGRLVPLLEPEIPPINTLYLAARTGTVDRPHISAVHSTLLSMARLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWC9</accession>
    <name>D3PWC9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1583</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1583"/>
    <dbReference type="EnsemblBacteria" id="ADD41286">
        <property type="protein sequence ID" value="ADD41286"/>
        <property type="gene ID" value="Snas_1583"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1583"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023858_0_0_11"/>
    <dbReference type="OMA" id="AHENECL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="210"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="528" mass="56436" checksum="4D2E11909EC92DDB" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWF1</accession>
    <name>D3PWF1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1605"/>
    <dbReference type="EnsemblBacteria" id="ADD41308">
        <property type="protein sequence ID" value="ADD41308"/>
        <property type="gene ID" value="Snas_1605"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1605"/>
    <dbReference type="eggNOG" id="ENOG5032YDP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133073_1_0_11"/>
    <dbReference type="OMA" id="CWNAKDR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="80" mass="9068" checksum="71E66FBBD2BC9864" modified="2010-04-20" version="1">MLAGVQAVEDGPDGRWHVRNLPGGGSAKTYRCPGCDQEIPPGVPHLVAWPADGSTEERRHWHRPCWRARYRRGPSNSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWZ0</accession>
    <name>D3PWZ0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020785.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5584"/>
    <dbReference type="EnsemblBacteria" id="ADD45214">
        <property type="protein sequence ID" value="ADD45214"/>
        <property type="gene ID" value="Snas_5584"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5584"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_3_0_11"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="5"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="314"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="401" mass="43713" checksum="63CFE9EDE0146857" modified="2010-04-20" version="1">MSRPRVLIIGAGLGGLALAHGLRDAGVDHLVVERDASVRSRRQGYRIHINADGSTALYEVLPKRLWELFRATASIPGPVGEFYDHRFDVVHRFEADGSARTVHGLPEHLNVNRLTLREILATGLDTVRYGRTFTGYRRDADGRVVAHFADGGTETGDLLVAADGVHSRVRRQRLPHARVVDSGLRLIYATVPLTPATRPLFPEGMFGGYSAILGPKHRHLGGAPVEFAEPLSRTASRIAADASLTEHRSYMTSAFGARVEDLPDDEELFAMNPSALRGLALDMMDDWHPRARRMVEHWELSSVLPLLLRTSVPTEPWPASEVTLLGDAVHAMSPAGGSGANAAMLDGAILAARLREVRDGKPLLEAVAEYENAMREHGFAAVRMSADNGHRMLGQDPLPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX08</accession>
    <name>D3PX08_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5602</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5602"/>
    <dbReference type="EnsemblBacteria" id="ADD45232">
        <property type="protein sequence ID" value="ADD45232"/>
        <property type="gene ID" value="Snas_5602"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5602"/>
    <dbReference type="eggNOG" id="COG0559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039929_3_0_11"/>
    <dbReference type="OMA" id="QQVLMTY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="292" mass="30455" checksum="6C49EF9A22D2CB22" modified="2010-04-20" version="1">MLQQLANGLFSGAIYALFAIGFTLVFGILRHLNLAHAAIYTAGALIGIELVEGQGLPLWLAFPLAILAGTALGLILERSAFRPLAGRRDEHFAGLISSVAFGGMLIALLQARFGSEPRSFSQSAFPNEILTIAGVTVSLAQLLTLGLALALMLGLAWLLSKSALGRAMRAVAENPRAARVLGINVEGVTAGTYALSSALGSCAGVLMALNVGQGDLRMGLSIELTGFAVIILGGLGSLWGAMAAGLLLGFAEAFTVHLIDSTWKNVVAFVLLFVILLTRPQGLFGQVKTREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX82</accession>
    <name>D3PX82_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction protein with Nacht domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016916.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1642"/>
    <dbReference type="EnsemblBacteria" id="ADD41345">
        <property type="protein sequence ID" value="ADD41345"/>
        <property type="gene ID" value="Snas_1642"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1642"/>
    <dbReference type="eggNOG" id="COG5635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_300313_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="115"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="911" mass="99975" checksum="79AEE4517AC2FAA6" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX84</accession>
    <name>D3PX84_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type I phosphodiesterase/nucleotide pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016918.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1644"/>
    <dbReference type="EnsemblBacteria" id="ADD41347">
        <property type="protein sequence ID" value="ADD41347"/>
        <property type="gene ID" value="Snas_1644"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1644"/>
    <dbReference type="eggNOG" id="COG1524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043662_0_0_11"/>
    <dbReference type="OrthoDB" id="191097at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049530" evidence="2">
        <location>
            <begin position="25"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="519" mass="57421" checksum="480EBC9D65ED2456" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXB0</accession>
    <name>D3PXB0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1671</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1671"/>
    <dbReference type="EnsemblBacteria" id="ADD41373">
        <property type="protein sequence ID" value="ADD41373"/>
        <property type="gene ID" value="Snas_1671"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1671"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022757_1_0_11"/>
    <dbReference type="OMA" id="TWTAVMQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048442" evidence="2">
        <location>
            <begin position="29"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="495"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="530"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="573"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="608"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="3">
        <location>
            <begin position="43"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="633" mass="67611" checksum="27B0BEA09341C474" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXZ9</accession>
    <name>D3PXZ9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="4 11">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Snas_5698</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ALAD family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="4 11"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020899.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5698"/>
    <dbReference type="EnsemblBacteria" id="ADD45328">
        <property type="protein sequence ID" value="ADD45328"/>
        <property type="gene ID" value="Snas_5698"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5698"/>
    <dbReference type="eggNOG" id="COG0113">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035731_0_0_11"/>
    <dbReference type="OMA" id="YQMDYAN"/>
    <dbReference type="OrthoDB" id="677575at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="PTHR11458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001415">
        <property type="entry name" value="Porphbilin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD45328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="335" mass="35896" checksum="646FB5B91432D0A5" modified="2010-04-20" version="1">MSETVEPSGFPRIRPRRLRQGSAMRRMVAETRVHPSDLMLPMFVREGLDAPRPIPSMPGVMQHTRESLRKAVVAAAHAGVGGVMIFGVPAEKDATGSGAIDPDGIGNLALADVTAEVGDSLVVVSDLCLDEFTDHGHCGVLAADGSVDNDATLERYADMAIAQAQAGAHMLGASGMMDGQVGYVRTALDRAGFENTGVFAYAVKYSSAAFGPFREAVESALQGDRRSYQQDPANAREALREVELDVAEGADIVMVKPGLPYLDIIRAVSEHVTVPVAAYQVSGEYSMVEAAAANGWIDRERMMLESLVSIKRAGASIIATYWAEEAARLLREERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY27</accession>
    <name>D3PY27_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5726"/>
    <dbReference type="EnsemblBacteria" id="ADD45356">
        <property type="protein sequence ID" value="ADD45356"/>
        <property type="gene ID" value="Snas_5726"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5726"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063235_0_0_11"/>
    <dbReference type="OMA" id="YWHTCLA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="246"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="333" mass="36927" checksum="85EE9DE7F461B0DD" modified="2010-04-20" version="1">MDVAWGLMIRFVLGVEDLVDTRFAVSPLQETVLSLRVLRDPGWYALHLPWRRMVLPRLDGLDLGLLLALVGRRHTLPDFLTPRPTSFAPAFEDEWDVARRAAPEVVRRELTAAYEPDAVPEVLRDAAGGDVGLLGEAVCGVLRRYWQLAIEPFWERMRLVMEADMTYRARQLAVGGARLLFADMHPHLRWRDGVLSVDKVVGEHRVVASGRGLLLIPSVFAHQPAPPVTPDEPPVLAYPSRGVATLWASAPVAESSALDSLLGVAKARILLLLEEPLATSEIARRLDVTPSAVSQQLRVLHDNGLVARARQGRQVLYRRSSLGDQLARRKAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYB4</accession>
    <name>D3PYB4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017052.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1784"/>
    <dbReference type="EnsemblBacteria" id="ADD41481">
        <property type="protein sequence ID" value="ADD41481"/>
        <property type="gene ID" value="Snas_1784"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1784"/>
    <dbReference type="HOGENOM" id="CLU_771407_0_0_11"/>
    <dbReference type="OrthoDB" id="2027854at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009677">
        <property type="entry name" value="DUF1266"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06889">
        <property type="entry name" value="DUF1266"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="359" mass="41502" checksum="F8EEA8C14827C68D" modified="2010-04-20" version="1">MANQIEELEKSVKGTFADGDFHFDHPNSVLRINSLFSRWSTSAMAPLALGLLGLIATGVTVFVASSTVMLTALGLSVLMFVLFGLTFANPGFVIDFRQRQVRYRKHRIPFDRIRREQFSFDHGDYVRLSFHGPGFKKHIAEFKTSETQQAYYFQEHLLRLFESPDMWSVFTYGSKLTPVQWWIQGVSAVFTVDWGMPLGELGDFSGPFKSLGRTGISRALERDWGIRDREGMVAQIESLARDGHREQFAQAGIPGKYLAWDYARALWMQRMGFILGWFDEEYCWDTMLPLARDVQRHYSGWAEMNHWYLEGRRLWSAAVSDGKPDPVQAQRERTAERLAADPKCPWNFLPWDLPLHRDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYD6</accession>
    <name>D3PYD6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine protein kinase with PASTA sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1807</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017074.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1807"/>
    <dbReference type="EnsemblBacteria" id="ADD41503">
        <property type="protein sequence ID" value="ADD41503"/>
        <property type="gene ID" value="Snas_1807"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1807"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_469211_0_0_11"/>
    <dbReference type="OMA" id="TITDFAY"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03793">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00740">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51178">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="4">
        <location>
            <begin position="500"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="584" mass="61835" checksum="9B283C840012F220" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYF0</accession>
    <name>D3PYF0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FolC bifunctional protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1821</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017088.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1821"/>
    <dbReference type="EnsemblBacteria" id="ADD41517">
        <property type="protein sequence ID" value="ADD41517"/>
        <property type="gene ID" value="Snas_1821"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1821"/>
    <dbReference type="eggNOG" id="COG0285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015869_1_2_11"/>
    <dbReference type="OMA" id="HTPSFFE"/>
    <dbReference type="OrthoDB" id="1232874at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="6">
        <location>
            <begin position="42"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="5">
        <location>
            <begin position="290"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="428" mass="45285" checksum="5A6E4A38E30E6B2A" modified="2010-04-20" version="1">MTMEMADLFSRRQGDRSETVARMGRLLAALGQPQSHFAAIHVTGTNGKTTTARMIEALLREHGVHTGAFISPHLQDVRERVLVDGEPITEDDLYEWLSHVDINGAAVAGPGGHTPSFFETMTALAFSHFAREKVDVAVVEAGRGGLRDATNVLHAPVAVLGPVALDHPDLGSTTAEIAADKADIIAPEGTVVIGPQEDQAAAAIAAAAHNRRARSLRHGVDLEVRDWQPTTTGQWFRAVLPGGVTIPVDLPLVGRHHADNALLALAAVQAWRGEVDDEAAWRCLSKFTAPGRCEIVRRRGKAAVWLDGAHNPAAASALATALAEIPGTARVILVAGIAADKDTDGVLAALAPVTHRAVLAPVPNARGGDPQRHRHTLAAHGIRPYLAANADEALDMADQLARQRDVVLVTGSLYTVGAVRDRLGLVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYH1</accession>
    <name>D3PYH1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">3-hydroxybutyryl-CoA dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.1.157</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1842</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.157" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017109.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1842"/>
    <dbReference type="EnsemblBacteria" id="ADD41538">
        <property type="protein sequence ID" value="ADD41538"/>
        <property type="gene ID" value="Snas_1842"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1842"/>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_2_0_11"/>
    <dbReference type="OMA" id="CKLGFGH"/>
    <dbReference type="OrthoDB" id="862072at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008691">
        <property type="term" value="F:3-hydroxybutyryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="5">
        <location>
            <begin position="4"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="4">
        <location>
            <begin position="186"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="283" mass="29792" checksum="2ABDCD5AF75088FF" modified="2010-04-20" version="1">MAGQVAIIGAGLMGSGIAQVAAVSGWTVTLRDLTDEATARGVANIRGSLEKFAAKDKISTADAEAALGRITTTTDLDAAAEADIVVEAVFERLDVKQDIFTELDKICRDSTVLATNTSAIPITQIAAVTSRPESVVGTHFFSPVPMMKLCELVRGLKTSDATLATARSFAEEIGKTCVVVNRDVAGFATTRLICALVMEAVSLVENGVISAEDLDVACKLGFGHAMGPLATTDLTGLDVLRHATENIYNDTGDSKFFPPELLSRMVAAGDHGRKTGKGFYDYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYJ9</accession>
    <name>D3PYJ9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2017 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017137.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1870"/>
    <dbReference type="EnsemblBacteria" id="ADD41566">
        <property type="protein sequence ID" value="ADD41566"/>
        <property type="gene ID" value="Snas_1870"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1870"/>
    <dbReference type="eggNOG" id="ENOG5032Z6K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087287_1_0_11"/>
    <dbReference type="OMA" id="KPMVMAY"/>
    <dbReference type="OrthoDB" id="1738659at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018561">
        <property type="entry name" value="DUF2017"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09438">
        <property type="entry name" value="DUF2017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2017" evidence="1">
        <location>
            <begin position="9"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="202" mass="22139" checksum="B47B3F835FA459CC" modified="2010-04-20" version="1">MAGYFEPLSGGGATILLGQVEISVLHGYATQLLDLLGPGQEPAHGDAEALLASVFTDQPDEPPTDPVLARLFPDAYDDPDRPPDDETRAASAEFRRYTESDMRARKRGDILTLIRCLETLTPSEPDGTELRLNEDECRQWLGALNDLRLALGTRLDITGDHDSEAFLQLPDSDPRKPSAMVYLWLSGLQETLIDSLTGSTDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYQ1</accession>
    <name>D3PYQ1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 14">Crossover junction endodeoxyribonuclease RuvC</fullName>
            <ecNumber evidence="11 14">3.1.21.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Holliday junction nuclease RuvC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Holliday junction resolvase RuvC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ruvC</name>
        <name evidence="15" type="ordered locus">Snas_3828</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 14">Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 14">Belongs to the RuvC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="11 14"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019055.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3828"/>
    <dbReference type="EnsemblBacteria" id="ADD43484">
        <property type="protein sequence ID" value="ADD43484"/>
        <property type="gene ID" value="Snas_3828"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3828"/>
    <dbReference type="eggNOG" id="COG0817">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091257_0_2_11"/>
    <dbReference type="OMA" id="AICHIWR"/>
    <dbReference type="OrthoDB" id="1815080at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16962">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00034">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020563">
        <property type="entry name" value="X-over_junc_endoDNase_Mg_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002176">
        <property type="entry name" value="X-over_junc_endoDNase_RuvC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30194">
        <property type="entry name" value="PTHR30194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02075">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00696">
        <property type="entry name" value="RSOLVASERUVC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00228">
        <property type="entry name" value="ruvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01321">
        <property type="entry name" value="RUVC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="14">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD43484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="176" mass="18353" checksum="7738DE38489BA6BC" modified="2010-04-20" version="1">MRVLGVDPGLTRCGVGIVEGAPGRPCRLVGVHVVRTDPEAALPDRLLRLDTALAQLVERYQPDAVAVERVFSQHNVASVIGTAQASAVAVLAGARAGVTVATYTPSEAKAAITGSGVADKKQMTTMVTKLLRLDAPPKPADAADALALAICHVWRGGTQARFTAARDKTILKGEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYT7</accession>
    <name>D3PYT7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-binding 9 siderophore-interacting domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019091.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3865"/>
    <dbReference type="EnsemblBacteria" id="ADD43520">
        <property type="protein sequence ID" value="ADD43520"/>
        <property type="gene ID" value="Snas_3865"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3865"/>
    <dbReference type="eggNOG" id="COG2375">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040923_2_0_11"/>
    <dbReference type="OMA" id="PYAWIAG"/>
    <dbReference type="OrthoDB" id="1630289at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013113">
        <property type="entry name" value="FAD-bd_9_SIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007037">
        <property type="entry name" value="SIP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039374">
        <property type="entry name" value="SIP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30157">
        <property type="entry name" value="PTHR30157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08021">
        <property type="entry name" value="FAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04954">
        <property type="entry name" value="SIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="311" mass="34238" checksum="0B20D4E0DCC1937C" modified="2010-04-20" version="1">MSTVTTEIPSWRTFPVTVRRLRRLSPSFLRVTFTGDDLDRFADNGFDVRVKLLLPAPACGLSKLPDGADWFTKLRALPVEEQCPLRTYTVRAVRQTRREVDVDIVIHPEAPGGDGPVATWARRIQTGDEIVLLGPNGEFDGFHGGMDFQPPDSTHRVLIVGDETAVPAACAIVERLPGHIETQVLLEVPETADARAIEADLPETPACVRVAVLPRDGAEHGAKLIPAVREVMTRLLPHTASGTEVEDVDVDTTLLWESPGAEARTSHGLYAWLAGEAAVIKTLRRHLVSERGVDRKSVAFMGYWRRGKAEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYU2</accession>
    <name>D3PYU2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019096.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3870"/>
    <dbReference type="EnsemblBacteria" id="ADD43525">
        <property type="protein sequence ID" value="ADD43525"/>
        <property type="gene ID" value="Snas_3870"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3870"/>
    <dbReference type="HOGENOM" id="CLU_2036607_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="121" mass="13467" checksum="DA685D10A8C4D582" modified="2010-04-20" version="1">MTSAEEAVVAEIAENSRKIREFEEKLAAAEITVTSPGNHVRMTCDSVGNIHSIQFNRAVPHDVDHRQLSRELVQTLNSARNAGNVAREKFLNGLEMDGDKVGDRLRHSVTADEILRRVFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYV3</accession>
    <name>D3PYV3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019107.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3881"/>
    <dbReference type="EnsemblBacteria" id="ADD43536">
        <property type="protein sequence ID" value="ADD43536"/>
        <property type="gene ID" value="Snas_3881"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3881"/>
    <dbReference type="eggNOG" id="ENOG5033311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1502580_0_0_11"/>
    <dbReference type="OrthoDB" id="1401012at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="179" mass="20236" checksum="435A73071EECC8F7" modified="2010-04-20" version="1">MNRGHRRERRQRPGQVRAQLVTEFTRIRRLKLATFGVVAAAVVAAVPVALRLDDVTRDPAFVALDELALPHWASAKPRDAAAGSRWCVGRCRVRERVWQSKRGVDDTVKVYAGALSTEHWHRLDSGRCPTRTQLGQYRCYHRDEYALDLWVRPAECPDVKQLCPGSTVSAVIRPTPEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYZ3</accession>
    <name>D3PYZ3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5792"/>
    <dbReference type="EnsemblBacteria" id="ADD45422">
        <property type="protein sequence ID" value="ADD45422"/>
        <property type="gene ID" value="Snas_5792"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5792"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062440_3_0_11"/>
    <dbReference type="OMA" id="QYVFEYL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="40"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="239" mass="26045" checksum="C9F2CA842B664B66" modified="2010-04-20" version="1">MTDMTVLLKRLDALDDLPDAVALRERGYDLLRPADGQVIVDVGCGSGRAVSELARRGVRAHGVDPSEVMIDAARQRWSELDFHLAPAERLPFGDGEVDGFRADKVLHALEDPGAAIAEALRVLKPGGRAVLVGQDWDHFVVDADDHDLTRRIVRTRAAGMPSPNIARGYGNLLRDNGFTDVTMEMYSFRPPAEAFLGTIAETAEDIPGGKDWLAEQHRRAAEGRTFIAVPIFLAAGTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ50</accession>
    <name>D3PZ50_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5850</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5850"/>
    <dbReference type="EnsemblBacteria" id="ADD45479">
        <property type="protein sequence ID" value="ADD45479"/>
        <property type="gene ID" value="Snas_5850"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5850"/>
    <dbReference type="eggNOG" id="COG3154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070584_1_0_11"/>
    <dbReference type="OMA" id="YRWLWGR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010872">
        <property type="entry name" value="MDMPI_C-term_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07398">
        <property type="entry name" value="MDMPI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048116" evidence="1">
        <location>
            <begin position="21"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="MDMPI_N" evidence="3">
        <location>
            <begin position="14"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="MDMPI_C" evidence="2">
        <location>
            <begin position="139"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="249" mass="27587" checksum="179228820BC36218" modified="2010-04-20" version="1">MQFSRLTSCLTADAARMAKAAEGNMDARVPTCPEWTMTDLLEHVAHVYMHKTECIRNGQPKSWPPPRDPEVPTLTLMRQGLGDLLAEFTPREPADAAYTWYDPDQTVGFWIRRMAQETVIHRVDAELAAGVALGPIDEELAVDGIDELLRIFVGWSSHKWAEEVADSIGKLLPKPVAVTSGDTTWVLRPVDGSIDVDSEAASDVAVTISGEPAPLLLWLWRRGDDEGIQFDGDEQAARALHELIKEFTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZA9</accession>
    <name>D3PZA9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1887"/>
    <dbReference type="EnsemblBacteria" id="ADD41583">
        <property type="protein sequence ID" value="ADD41583"/>
        <property type="gene ID" value="Snas_1887"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1887"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100916_0_0_11"/>
    <dbReference type="OMA" id="CAEYKIR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="2"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="184" mass="20837" checksum="B6FDE56A1D4EB910" modified="2010-04-20" version="1">MKILDLVLHPVRLRILHAMYGGQSHTTSDLCAHLADVPKTSVYRHVSLLTEAGMLEVVDEKRVHGAVERHYRLRRDRTTIGPEAARSMSTEDHRQGFAAALAALLAEFNAYLDRDDAVPVEDYVGYQQLPLWLSREELHDLVDKFVELIEPLSRNEPTPERGLHMLSPIVFPLQRPPGQASEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZI7</accession>
    <name>D3PZI7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1965</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017232.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1965"/>
    <dbReference type="EnsemblBacteria" id="ADD41661">
        <property type="protein sequence ID" value="ADD41661"/>
        <property type="gene ID" value="Snas_1965"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1965"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_0_1_11"/>
    <dbReference type="OMA" id="WGEQDQP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="24"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="234" mass="25772" checksum="1E6970460EC706DE" modified="2010-04-20" version="1">MSTPDAQSLLWGKRPSPGRGRKPSLSVDGIVTVAIALADAEGLAGLSMPRLAEELGCGVMTLYRYLPGKEELVALMMDTCLGQPPRLSDSPDWRGNCRAWALALREVCHEHPWWIDIALHNRVAGPNETAWLEAELRALAPLRLDPVVTMNVALAISSYVRGAVQPELRATPGPRFGFVDYPETHHRYPLVNEMFHAPAFQSGEGLSDFFGFGLERLLEGIDNLHATHGDDLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZL4</accession>
    <name>D3PZL4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator, Crp/Fnr family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017259.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1992"/>
    <dbReference type="EnsemblBacteria" id="ADD41688">
        <property type="protein sequence ID" value="ADD41688"/>
        <property type="gene ID" value="Snas_1992"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1992"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056341_0_0_11"/>
    <dbReference type="OMA" id="DPMNQVE"/>
    <dbReference type="OrthoDB" id="250058at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045641">
        <property type="entry name" value="MmpI-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19307">
        <property type="entry name" value="PCLP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="102"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="472" mass="51779" checksum="9797B11179068A17" modified="2010-04-20" version="1">MTSVDDNANVEATESPQLSLSTAAARNLATTTKTVPQMQGISSRWLLRLLPWVQTNGGTFRVNRRLSYAVGTGRVQFSNVGDRVQVIPPTLSELPLLRGFDDEPTLEAIAGVLEQRDFEAGQVIVSVGDTIDTGFLMAHGKASKIGTGKYGDDTKLGMLADGDYFGEDILRPEPGRWPYTVKAVTPCTLLVMRRDALRGLVDNSEPLNEHINRLLALPDLPRNDDDEAAIDLAAGHDGEPDLPGTFVDYELSPREYELNVAQTVLRVHSRVADLYNDPMNQVEQQLRLTVEALRERQENEIVNNPSFGLLDNADLKQRISTDTGPPTPDDMDDLLSIVWKEPGFFLAHPRTIAAFGQECSRRGIYPDAVEVAGHRLPGWRGVPIYPCNKIPVTEGDVSSILLMRTGQENQGVVGLHQIGLPDEYEPGLSVRFMGINEKGIISYLVSTYYSAAVLVPDALGVLENVQIGRPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q055</accession>
    <name>D3Q055_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5957</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021155.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5957"/>
    <dbReference type="EnsemblBacteria" id="ADD45584">
        <property type="protein sequence ID" value="ADD45584"/>
        <property type="gene ID" value="Snas_5957"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5957"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_0_1_11"/>
    <dbReference type="OMA" id="MNTGRYP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003012">
        <property type="entry name" value="Tet_transcr_reg_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00400">
        <property type="entry name" value="TETREPRESSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="6">
        <location>
            <begin position="23"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="229" mass="24871" checksum="A02F278C2A295BB7" modified="2010-04-20" version="1">MGTDIDTLLWQGQTRPNRGPKPSLSLDRIVTAAVAIADAEGLEGLSMKSLATRLNSGVMSIYRYVPGKEELIALMIDAAVGEPPRVPDGTGWREGIRLCARAIRGFFLAHPWALPLVTKGRAIGPNETGWLESQLTALSSLDVSPGTRLNLAMAVSSYVRGAVTPELFGEDNGELRFAFLDHPDSHARFPMLAHTLTSIDPGTDEGFDSFFEFGLTRMLDGIAARFDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q065</accession>
    <name>D3Q065_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1524 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021165.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5967"/>
    <dbReference type="EnsemblBacteria" id="ADD45594">
        <property type="protein sequence ID" value="ADD45594"/>
        <property type="gene ID" value="Snas_5967"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5967"/>
    <dbReference type="eggNOG" id="COG2356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043034_3_0_11"/>
    <dbReference type="OMA" id="KSGICHD"/>
    <dbReference type="OrthoDB" id="1510738at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011089">
        <property type="entry name" value="DUF1524"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07510">
        <property type="entry name" value="DUF1524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048754" description="DUF1524 domain-containing protein" evidence="1">
        <location>
            <begin position="36"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1524" evidence="2">
        <location>
            <begin position="107"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="226" mass="25182" checksum="632B3F32B1197313" modified="2010-04-20" version="1">MRRSFPSNVPGTVGVAAIVTLTVTGCGFTATPAEADSVDTTLTEAIADLPVEDEVRDGYDRDKFPHWVDVDDDGCNARYEVLIAEAVTAPDVGSGCRLTGGKWTSYYDGEEWTQPADLDVDHFVPLAESWDSGSRDWSEADRERFANDLDEERGLAAVTDNVNQSKGDKDPAEWLPPLEKVHCRYLQEWTVVKSRWRLSVDQEEKDKLEELADGCDNVKLSFEYAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0D9</accession>
    <name>D3Q0D9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Type III pantothenate kinase</fullName>
            <ecNumber evidence="6">2.7.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">PanK-III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantothenic acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaX</name>
        <name evidence="7" type="ordered locus">Snas_0081</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16373"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NH4(+)</name>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
        </cofactor>
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">A monovalent cation. Ammonium or potassium.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the type III pantothenate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.33" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015374.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0081"/>
    <dbReference type="EnsemblBacteria" id="ADD39803">
        <property type="protein sequence ID" value="ADD39803"/>
        <property type="gene ID" value="Snas_0081"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0081"/>
    <dbReference type="eggNOG" id="COG1521">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066627_1_0_11"/>
    <dbReference type="OMA" id="HEPWLTL"/>
    <dbReference type="OrthoDB" id="2039419at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01274">
        <property type="entry name" value="Pantothen_kinase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004619">
        <property type="entry name" value="Type_III_PanK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34265">
        <property type="entry name" value="PTHR34265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03309">
        <property type="entry name" value="Pan_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00671">
        <property type="entry name" value="baf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="105"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="6"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>a monovalent cation</name>
            <dbReference type="ChEBI" id="CHEBI:60242"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD39803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="255" mass="27148" checksum="E80D16DAE337711B" modified="2010-04-20" version="1">MLLCVDIGNTNTVLATFEGETLVHSWRIKTDPRATADEMALTFRGLLAGDNVEVSAICVSSTVPQALRELRVMLSRYYAAKPTVLVAPGVRTGVQLAIDNPREVGADRIVNTHAAYNMYGGPSIIVDFGTSTNIDVISEKGEFLGGAFAPGIEISIDALASRAAQLQKVEPVKPRSVIGKNTVECLQSGIIYGFAGQIDGLVTRIIKQLGTGVSAVIATGGLAPVVIEECATITNYEPMLTLIGLRMIYERNAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0F1</accession>
    <name>D3Q0F1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0094</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0094"/>
    <dbReference type="EnsemblBacteria" id="ADD39815">
        <property type="protein sequence ID" value="ADD39815"/>
        <property type="gene ID" value="Snas_0094"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0094"/>
    <dbReference type="eggNOG" id="COG1565">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046703_0_0_11"/>
    <dbReference type="OMA" id="CDVTAHV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PTHR12049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD39815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="311" mass="33862" checksum="5B01F297E33DEEBD" modified="2010-04-20" version="1">MLPWSQAMRRALYGPGGFYTLNSPNRHFRTSAQFPLFATAIAELVRRTDSRLDHPEVFNLVDVGAGSGELLRRVLDEEDLNGRLRPVAVELRPAPPGLDERIEWRTSLPGGIIGLLMACEYLDNMPLDIAVADAAGAVRYELVDPGSGETRPGQPVSSVDADWLRAWWPLGQAGQRAEIGRSRDQEWARLCGNVSRGTVVAVDYGHTKDCRPPLGTVTGFLDGHQVAPVPDGTRDITAHVAMDSLGDGGLWTQRDALRELGISGSRPPLELSRTNPAEYIRALSRAGDAAELTDPAGLGAHHWLVLNLTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0H4</accession>
    <name>D3Q0H4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2015</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2015"/>
    <dbReference type="EnsemblBacteria" id="ADD41710">
        <property type="protein sequence ID" value="ADD41710"/>
        <property type="gene ID" value="Snas_2015"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2015"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="79"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="283" mass="30630" checksum="284C692F1B5BD8E0" modified="2010-04-20" version="1">MKRRPSGFNVMSPREKAGRYLLLCLVLVITVGPFLWQLSTSLKGLSEDIYTDTPSFLPTDPTLANYTRVGEQIPVWDYAVNSLIVAVIVVAGNAFGATLAGFALARLRFRGVKLVFALILATLVLPGEVTIISQYVTVRSLGFADTLIGVALPGTVAMLNILLMRAAFQAIPSEMDDSAVVDGANAWQRLIRVGLPNVKGMLSVVTIFAFIGAWDDFLWPLIVLNDPDNYTLTVGLQYLDGTFTANPRVIAAGTMIAFIPIVIVFAVLQRFFFRGVASGAIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0I4</accession>
    <name>D3Q0I4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenazine biosynthesis protein PhzF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017291.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2025"/>
    <dbReference type="EnsemblBacteria" id="ADD41720">
        <property type="protein sequence ID" value="ADD41720"/>
        <property type="gene ID" value="Snas_2025"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2025"/>
    <dbReference type="eggNOG" id="COG0384">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048756_0_1_11"/>
    <dbReference type="OMA" id="IVNGMSQ"/>
    <dbReference type="OrthoDB" id="1468060at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="279" mass="28959" checksum="1B0FC9CD082798E5" modified="2010-04-20" version="1">MISYEIVDVFTDRAFAGNPLAVVFGAETLTDAGMQAIAAEFNLSETAFVLPTTQDGATYRVRIFTPLRELPYAGHPSVGTAVTLARRGDIGHGAAIQECGVGLLPITVMEDEATLTGGEPSCGGPVDTAALLAAAGLADSDLTGPARFAGTGLEFPYLPVTDEAVTRAVSHPREDVPEVCLFAFDAATRVSHSRLFAPGHGVAEDPATGSAALGLGVYLVAEGLMPDDGTHSYVVEQGAERGRPSRLHCEVTAKDGAATEVRVRGRVVPVARGEFVALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q184</accession>
    <name>D3Q184_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_6040</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021235.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6040"/>
    <dbReference type="EnsemblBacteria" id="ADD45664">
        <property type="protein sequence ID" value="ADD45664"/>
        <property type="gene ID" value="Snas_6040"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6040"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_3_0_11"/>
    <dbReference type="OMA" id="WSGACLH"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="21572" checksum="93CA6C9BFD6254EF" modified="2010-04-20" version="1">MSVHIVAGFLLAVFPLIATPGASFTLMTQRVIPHGARHGVPVILGTIAGLYVHATLAAVGLSALVMRSAELFAVVKVVGAVYLVGLGLWTWRTSFGTSEAATTRTGAASGSTFVQALLGNVLNPKAASIFLTLVPQFLDSTRPIVPQILILVTAQSLLITVWLFGWAAVIGRAGRAFRSSAFTTVFRRITGTVLIGLGVRAAFGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1A6</accession>
    <name>D3Q1A6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021257.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6062"/>
    <dbReference type="EnsemblBacteria" id="ADD45686">
        <property type="protein sequence ID" value="ADD45686"/>
        <property type="gene ID" value="Snas_6062"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6062"/>
    <dbReference type="eggNOG" id="ENOG5033IBR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115334_1_0_11"/>
    <dbReference type="OrthoDB" id="1844263at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="23074" checksum="2EAE9E36986AF0AF" modified="2010-04-20" version="1">MTQIEIPLNGFVDYLRTKGAARVDVAARHLHQSTEPYSPARDFYRRALSAILAGRRSGDDRAVCEHALAEAPPARRTHYQAVMDGWLRYLPKLADTKHVPVHTGRWRGGNLTVRVTPHLGVRYPDGHVEALFLYLKAEPLPSADARAMLWLASAAMPEACPEARPVIVDVRRSRAFRDLPDTSSYPAWLMAEAGGYRHLREQLTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1N5</accession>
    <name>D3Q1N5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fumarate reductase/succinate dehydrogenase flavoprotein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0163</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015454.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0163"/>
    <dbReference type="EnsemblBacteria" id="ADD39883">
        <property type="protein sequence ID" value="ADD39883"/>
        <property type="gene ID" value="Snas_0163"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0163"/>
    <dbReference type="eggNOG" id="COG3573">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022946_0_0_11"/>
    <dbReference type="OMA" id="PEDHWPR"/>
    <dbReference type="OrthoDB" id="153138at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033765">
        <property type="term" value="F:steroid dehydrogenase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014614">
        <property type="entry name" value="UCP036654"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43260">
        <property type="entry name" value="PTHR43260"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036654">
        <property type="entry name" value="UCP036654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="3">
        <location>
            <begin position="4"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD39883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="548" mass="59603" checksum="20B2E48B83F25FC7" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1W7</accession>
    <name>D3Q1W7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017405.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2140"/>
    <dbReference type="EnsemblBacteria" id="ADD41834">
        <property type="protein sequence ID" value="ADD41834"/>
        <property type="gene ID" value="Snas_2140"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2140"/>
    <dbReference type="eggNOG" id="ENOG50333S1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_865760_0_0_11"/>
    <dbReference type="OrthoDB" id="2134147at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="364" mass="39246" checksum="2C0BC853CA7EBE84" modified="2010-04-20" version="1">MTSTSRPPARGSENNGSGGSDGSGSGEDKVKGPTDKELEDAVNKLVEVAKKKAQEEADQARRSVEGKKSFEGDVLEYPYTREEVTKMIEDGAKEIKERFAAVYTPKPDDFDTMISRMQQVEAVLGAYEPSKNTTKETPVIGGGGDLELLRTSVSDMSDWQGKLKNAFVDNYLTPFPRITVTQGGLARFLRHQAEWMQAIYKRRRYDAKKTADQGVEAIEAIDDSKGSEAAIALAAIIGLATLLGPMGSSLAFGLGTSAVVAGTGIGAEFIEEDKEVPLGADTVQGVIDNVYKALEESDKTMVEEEGKVLDALKQIEGVVYPLVMGPDIDKGTELTPMRPAIVDTMDVEELKDGITVYDRHPGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q210</accession>
    <name>D3Q210_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6 7">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplS</name>
        <name evidence="8" type="ordered locus">Snas_2185</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6 7">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017448.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2185"/>
    <dbReference type="EnsemblBacteria" id="ADD41877">
        <property type="protein sequence ID" value="ADD41877"/>
        <property type="gene ID" value="Snas_2185"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2185"/>
    <dbReference type="eggNOG" id="COG0335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103507_2_1_11"/>
    <dbReference type="OMA" id="TITVYYE"/>
    <dbReference type="OrthoDB" id="1698718at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018257">
        <property type="entry name" value="Ribosomal_L19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01015">
        <property type="entry name" value="RIBOSOMAL_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="114" mass="12854" checksum="0180A0D8A16FA594" modified="2010-04-20" version="1">MNTLDALDAVSVRADIPDFRAGDTIKVHVRVVEGSRSRIQIFQGVVIRRQGSGLRETFTVRKMSSGIGIERTFPVNSPVIDKIEVATRGDVRRAKLYYLRELRGKAAKIKEKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q229</accession>
    <name>D3Q229_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017467.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41896">
        <property type="protein sequence ID" value="ADD41896"/>
        <property type="gene ID" value="Snas_2205"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2205"/>
    <dbReference type="eggNOG" id="ENOG502ZVDD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166791_1_0_11"/>
    <dbReference type="OrthoDB" id="2089675at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024341">
        <property type="entry name" value="DUF2631"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10939">
        <property type="entry name" value="DUF2631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="74" mass="8158" checksum="43C0D5ECD221F6A1" modified="2010-04-20" version="1">MAGNNEPVTSPDQRKPTNRKVAYTVTIAGIITMIAYLFGNHEGRVEDLWLLFTAGVLAIGLAADWLMVRNGLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q286</accession>
    <name>D3Q286_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CDP-alcohol phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019390.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4168"/>
    <dbReference type="EnsemblBacteria" id="ADD43819">
        <property type="protein sequence ID" value="ADD43819"/>
        <property type="gene ID" value="Snas_4168"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4168"/>
    <dbReference type="eggNOG" id="COG0558">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1154461_0_0_11"/>
    <dbReference type="OMA" id="WMTSATI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="243" mass="25744" checksum="3585CEE8FF111F8D" modified="2010-04-20" version="1">MNTDQQAPSSIPPSVFLSHLRSGGLFTRVINQRIAAVFASVAYRFRLHPTVLTLVGFVLSLAGSGVVIAAAPTLPDSGIGWRIGVAVLAFVAWQAAYSLDCADGQLARVTKTTSPEGAKIDILCDIFTQVFFVAAVASVALAFYPDLSPVFAVGFGAVWMTSATIAVLDKGGEDVSLISSESLPILLAKAIRDYGTVITAVCLLVAVWPSGMLWFVLFYAALNGLYLLVLIARTASRSMKNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2P7</accession>
    <name>D3Q2P7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021369.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6175"/>
    <dbReference type="EnsemblBacteria" id="ADD45798">
        <property type="protein sequence ID" value="ADD45798"/>
        <property type="gene ID" value="Snas_6175"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6175"/>
    <dbReference type="eggNOG" id="ENOG50346FA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113740_0_0_11"/>
    <dbReference type="OMA" id="NIVWNRE"/>
    <dbReference type="OrthoDB" id="1800612at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048819" evidence="1">
        <location>
            <begin position="26"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="155" mass="15554" checksum="934F6843A96B12AC" modified="2010-04-20" version="1">MRTLGKLIGLSAFAMTLAIPAAAQAAAANLVDGTVATSGTNCSWTNAATSDNPPNTLTIDQASVSVTCDDGTPITLNNSPQVTFDDGAGTATVDKLNITGTKSGISCTYEATGVQFARTGDTRDYTGGPISAGKTDGSILCPGTMTLDSAAVSFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2S9</accession>
    <name>D3Q2S9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">1-phosphofructokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_6208</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6208"/>
    <dbReference type="EnsemblBacteria" id="ADD45830">
        <property type="protein sequence ID" value="ADD45830"/>
        <property type="gene ID" value="Snas_6208"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6208"/>
    <dbReference type="eggNOG" id="COG1105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050013_0_2_11"/>
    <dbReference type="OMA" id="QLNEPGP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01164">
        <property type="entry name" value="FruK_PfkB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017583">
        <property type="entry name" value="Tagatose/fructose_Pkinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000535">
        <property type="entry name" value="1PFK/6PFK/LacC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03168">
        <property type="entry name" value="1-PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="5">
        <location>
            <begin position="26"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="312" mass="32812" checksum="1F4744C4581F2CE4" modified="2010-04-20" version="1">MDTPVILTVALNAALDVTYSIDAELRPHATYRVGTVAEMPGGKALNTARILHTLRDPVLATGLLGGHTGERIAERIPAGLRHRFVRVDGESRRALVVADPADATGFWEPGPEITSEEWQRFRDRFDGLLRVARVVVLSGSLPQGLPVDAYAQLVAAARDRGVTTILDCDGEALRAALPQRPDVIKPNAHELAAAVPDADLSTVDGIRKAAETLRAAGARAVIASLGPDGLLAVLPDAAFTAAPPETVSGNPTGAGDACVAGLARGVLYDTGWPTRLTDAVALSAAAVRSPVAGRVDVTDYLTLRHHIHLKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q367</accession>
    <name>D3Q367_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0319</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40037">
        <property type="protein sequence ID" value="ADD40037"/>
        <property type="gene ID" value="Snas_0319"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0319"/>
    <dbReference type="eggNOG" id="ENOG503339G">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_936612_0_0_11"/>
    <dbReference type="OMA" id="RWINPDA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="297" mass="32760" checksum="8D2D7F4CB274EE58" modified="2010-04-20" version="1">MSEETWRPLGVDDEDEVAQYDALHDGVPSWMASPYWAWNQDALTIYRRYRDGSGRIAMLDTKLAEEMCQALRLSFPNLRTDAIDSRIGKEQLKTAMEYLVKHSAPLQIADYLLAHDGHAAHAEMDSLLERSKSVWTIGTRAGRPALVRRVPLGVQVAVDTVIGQAGQAGVRLAKAWEELYGLNPDASAAYRLAILAVEDAAVPVVSPNNQSATLGTVLKQIEDQKNWKLPMDREHPNAPSREVLVSMMRMLWHGQHDRHGGQPTAPGNVSVDEATIAVSLAASLVHWFEAGLIQRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q399</accession>
    <name>D3Q399_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015640.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0351"/>
    <dbReference type="EnsemblBacteria" id="ADD40069">
        <property type="protein sequence ID" value="ADD40069"/>
        <property type="gene ID" value="Snas_0351"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0351"/>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048112_0_0_11"/>
    <dbReference type="OMA" id="RKRAIFH"/>
    <dbReference type="OrthoDB" id="785253at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="239"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="467" mass="51989" checksum="7A6EC1ABB86D9AA5" modified="2010-04-20" version="1">MTTSNDVRIWAIETRKLKRGNSYRVVWFVAGKRQPPETFTTWAAADSFRSKLVAAHRKGELFDIDTGRPISWLKNENTMSWYELTCKYVQDKWSHVSPSHREYIADTLTDCTEALFKTDHAEQPEQAKLRLALRRWSFSARIRDGGEPPEGHVPALKWLENNTIDVADLGDEKKGGLLVRGVLARLSQTTKGKPAAANSFNNKRRVLNNCLKFAIEIGVLDANPLSLVTWRKAVVESAVDPEVVVNLDQATRLLGAVAEQGELGKRLKAFFGCMYFAALRPEEVIDLRRSNIANLPEEGFGLFRLTNADPSVGTAWTDTGKARQRRQLKHRAVGSNRPVPIHPDLVKLLKKHLDEFGVGRDGRVFVGPENGSAAHGYLRVFKAARKTAFTEAEQDSPLAARPYDLRHACVSTWLAAGVQAPRVAKWAGHSVDVLLKVYAKCIDGQEGVDLERVLHANATAQVDRGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3E5</accession>
    <name>D3Q3E5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FGE-sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017557.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2297"/>
    <dbReference type="EnsemblBacteria" id="ADD41986">
        <property type="protein sequence ID" value="ADD41986"/>
        <property type="gene ID" value="Snas_2297"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2297"/>
    <dbReference type="eggNOG" id="COG1262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023607_0_0_11"/>
    <dbReference type="OMA" id="EWEWQYA"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="2">
        <location>
            <begin position="510"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="669" mass="74620" checksum="86374C1F0A347196" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3I7</accession>
    <name>D3Q3I7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SNARE associated Golgi protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017599.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2342"/>
    <dbReference type="EnsemblBacteria" id="ADD42028">
        <property type="protein sequence ID" value="ADD42028"/>
        <property type="gene ID" value="Snas_2342"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2342"/>
    <dbReference type="eggNOG" id="COG0586">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044208_1_1_11"/>
    <dbReference type="OMA" id="SNARFQF"/>
    <dbReference type="OrthoDB" id="1928533at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="228" mass="24815" checksum="426A9AFDFC388C93" modified="2010-04-20" version="1">MANAEGVLDGITDWAVGLMETLGAPGAGLAVALENLFPPLPSEIILPLAGFTASKGDMNLIAAVVWTTIGSLVGALALYLVGAGIGRERLLRIAARLPLVKVSDIEKTEAWFHRHGTKAIFFGRMIPIFRSLISIPAGVERMPILPFLVYTTLGSLIWNSAFIAAGYLLGENWSVVETYVGVYSRGVVAVVGLAFVVWLVLRIRTNRRQRREPQLSMVEPGVYRSDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3M7</accession>
    <name>D3Q3M7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4296</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019515.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43944">
        <property type="protein sequence ID" value="ADD43944"/>
        <property type="gene ID" value="Snas_4296"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4296"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_2_0_11"/>
    <dbReference type="OMA" id="EKTVFNH"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="23511" checksum="FD6CD90B4F50745D" modified="2010-04-20" version="1">MSDELSLRERKKAQTRRDLIYTAIELVSAKGYDNVTVAEIAEAAQVSKMTVFNYFGSKDDLLMAAPERHVDDPTEAVRDRASGQTPVDAVREYFLAALLEQDPATGLSDNDTVRKLQRIASEVPSLRMRWASYVAEAQRRLAEYLATEDECDDLTADLVAAQIEGVRMALIRANIVRMVGGETAAEVYPEAKARAERAFALLETGLGDVLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q499</accession>
    <name>D3Q499_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6368</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021555.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6368"/>
    <dbReference type="EnsemblBacteria" id="ADD45984">
        <property type="protein sequence ID" value="ADD45984"/>
        <property type="gene ID" value="Snas_6368"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6368"/>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029425_12_3_11"/>
    <dbReference type="OMA" id="DGTYTQY"/>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="3">
        <location>
            <begin position="148"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="269" mass="28810" checksum="15A7AAAB640A5912" modified="2010-04-20" version="1">MSETHVVVFAHAGAHAHRRGCHRAPLFHRGKHRAPFTFPIPQQGRYALVVGAAVISAGAVALGSAAALPADGNGPSDSVVAVDQYATHAADSEAYGSMAEPPEAEARPQSAKAEPDSPITEQPAEKYWRAPLDDYDLTSLFGARWGMRHEGLDFGAPEGEPVYAVYPGRVKSAGWNYGGFGQLVIIDHGDGVETYYAHNSQIAVAEGQWVKAGQQISSVGNTGNSFGPHLHFELHVDGEPVDPKPYLFERGVDVETLADKVLTDEKPLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4A1</accession>
    <name>D3Q4A1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021557.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6370"/>
    <dbReference type="EnsemblBacteria" id="ADD45986">
        <property type="protein sequence ID" value="ADD45986"/>
        <property type="gene ID" value="Snas_6370"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6370"/>
    <dbReference type="eggNOG" id="ENOG5033A8R">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036478_2_0_11"/>
    <dbReference type="OMA" id="ERITIRM"/>
    <dbReference type="OrthoDB" id="1327142at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021373">
        <property type="entry name" value="DUF2993"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11209">
        <property type="entry name" value="LmeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048226" evidence="1">
        <location>
            <begin position="32"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="248" mass="26244" checksum="51986AE1448B53A5" modified="2010-04-20" version="1">MAKSSPRKKAIVWITTIVILLAVLVIGDRVAASIAGDQLSQVIANKATENDVKSAKPPVVTMGGFPFLTQVIAGEYTRIDIELVEVGNDTITLPKLDIIAHDVQADMSTAMGGSGPVKASRMEAEADISYDSLTKSIENTTNAEISAKDDSTLEIKLTMEVAGQQVEVVGGATVDVTDNKLVIQAQEFKPAEGQLPQGGDAVMNEVAQKFNKEIPLPSMPFDLKLGDPKFADDHIAVTATAKDVPLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4C2</accession>
    <name>D3Q4C2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Protein GrpE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">HSP-70 cofactor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">grpE</name>
        <name evidence="7" type="ordered locus">Snas_0365</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 5">Belongs to the GrpE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0365"/>
    <dbReference type="EnsemblBacteria" id="ADD40082">
        <property type="protein sequence ID" value="ADD40082"/>
        <property type="gene ID" value="Snas_0365"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0365"/>
    <dbReference type="eggNOG" id="COG0576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_933538_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_coiled_coil"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="PTHR21237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="SSF51064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="SSF58014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="175"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="203"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="232"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="273"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="31909" checksum="80204B352FC129D4" modified="2010-04-20" version="1">MTAEQNADATEAKESGPPEAETPDSGAADKDTAEESTDLATQLSERTADLQRITAEYHNYRKRVERDKSLAAEQTTATVVAGLLPVLDDIDRAREHGDLEGPFATVSEQLLNALIKLGLEVFGEKGDPFDPAVHEAVAHMVSPEVTETSCIDVMRRGYRLGERLLRPAMVAVAEPAEAETAETGKTEAVAEDAELSAETEEAVEAETEAKAEAEAEAAVEAEVEVEELAETKDEDATPNLDADVPSDEEQVKAEQVEDAVAEAAESDAEAGSEAVDEEKPESEKDKSAPDDTKKTENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4C5</accession>
    <name>D3Q4C5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015656.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40085">
        <property type="protein sequence ID" value="ADD40085"/>
        <property type="gene ID" value="Snas_0368"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0368"/>
    <dbReference type="eggNOG" id="ENOG502ZS8I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_717481_0_0_11"/>
    <dbReference type="OrthoDB" id="1972413at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="385" mass="41163" checksum="8E2287EA079B46A0" modified="2010-04-20" version="1">MGRTLGPFTDVSTARVDGAYEIYRGEDDDGREVEILTLGATSAKDPARRALLSDTVAWAHATRGPADASILSADLDSDQPYVVTLRQDGMRGVERMLERMLAMGPPSGPLSGVNQNSGQFPIVGPPTGHIPVVTGHTDPHGIPRVVSTPPSGSPVAPASPMASYVTKAQTSRPPWLVPMAVVLLLLVLIAGGFFVFYGMSGEDSDGTPGGGESGADDQNAQEMKPSWDDSLPPVKVVGDQTYTGDEGETIALARWPFAFKVTPGMTCEQPENLLAECAVPDQAEDTWAEIQVQECPDGCGEPAKNKLVNAFDMPGEEERVDANTQIGNEYFNDEDLYHVGMTRFYEPEPGHVLFVTVFASGNRSESAMQELHRIVNSVATQTSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4D8</accession>
    <name>D3Q4D8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40098">
        <property type="protein sequence ID" value="ADD40098"/>
        <property type="gene ID" value="Snas_0381"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0381"/>
    <dbReference type="eggNOG" id="COG5635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_348479_0_0_11"/>
    <dbReference type="OMA" id="MATELIC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="809" mass="87748" checksum="0226B8E0A87FD031" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Q9</accession>
    <name>D3Q4Q9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lipid A biosynthesis acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2406</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017660.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2406"/>
    <dbReference type="EnsemblBacteria" id="ADD42089">
        <property type="protein sequence ID" value="ADD42089"/>
        <property type="gene ID" value="Snas_2406"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2406"/>
    <dbReference type="eggNOG" id="COG1560">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049421_3_0_11"/>
    <dbReference type="OMA" id="GMRSYMR"/>
    <dbReference type="OrthoDB" id="1106624at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="300" mass="33333" checksum="7481660E08DD0019" modified="2010-04-20" version="1">MKDRLVDAGFGLAWRAVRALPESAAERIFRRIADRVWRSDGDGVRRLRSNLRRVVGPDTPADELETLTRDAMRSYCRYWMETFRLPSYSRSDILQRFTLDGWEVFDEHREAGTGVVLAIPHSGNWDLAGAWVCARGWPLTTVAERLSVDGVYEKFLDFRRGLGMEILPHTGGERPAHVVLAQRVAAGHIVPLVADRDLTEQGVEVDFFGGKTRMPGGPAYLALRTGAPLYTVVLRYDGPRHCYGKIEGPIEFPATGRLSHRIAAGTQAVADAFAAGIAAQPADWHMLQRLWLDDPATPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Y3</accession>
    <name>D3Q4Y3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2480"/>
    <dbReference type="EnsemblBacteria" id="ADD42163">
        <property type="protein sequence ID" value="ADD42163"/>
        <property type="gene ID" value="Snas_2480"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2480"/>
    <dbReference type="HOGENOM" id="CLU_3398641_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="31" mass="3273" checksum="7403F3014E9735FD" modified="2010-04-20" version="1">MLDLHGILAFPETRSALPITREGTVMAMSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q509</accession>
    <name>D3Q509_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoribosyl-AMP cyclohydrolase</fullName>
            <shortName evidence="7">PRA-CH</shortName>
            <ecNumber evidence="7">3.5.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hisI</name>
        <name evidence="9" type="ordered locus">Snas_2507</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PRA-CH family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2507"/>
    <dbReference type="EnsemblBacteria" id="ADD42189">
        <property type="protein sequence ID" value="ADD42189"/>
        <property type="gene ID" value="Snas_2507"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2507"/>
    <dbReference type="eggNOG" id="COG0139">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048577_5_1_11"/>
    <dbReference type="OMA" id="TGYRSCF"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01021">
        <property type="entry name" value="HisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026660">
        <property type="entry name" value="PRA-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="SSF141734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PRA-CH" evidence="8">
        <location>
            <begin position="37"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="120" mass="13045" checksum="61FF11CE2D13F5F8" modified="2010-04-20" version="1">MGTSSQLDTEIAARLKRDANGLVAAIAQDHDTGEVLMLAWMDDEALRRTLATGRATYYSRSRGEYWVKGETSGNTQQVKSVALDCDGDALLLRVEQRGPACHTGTATCFTGRELPLGVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q555</accession>
    <name>D3Q555_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pup--protein ligase</fullName>
            <ecNumber evidence="2">6.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Proteasome accessory factor A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Pup-conjugating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pafA</name>
        <name evidence="4" type="ordered locus">Snas_4459</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + [prokaryotic ubiquitin-like protein]-L-glutamate + [protein]-L-lysine = ADP + phosphate + N(6)-([prokaryotic ubiquitin-like protein]-gamma-L-glutamyl)-[protein]-L-lysine.</text>
            <dbReference type="EC" id="6.3.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein degradation; proteasomal Pup-dependent pathway.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein pupylation.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.19" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019675.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4459"/>
    <dbReference type="MEROPS" id="U72.001"/>
    <dbReference type="EnsemblBacteria" id="ADD44104">
        <property type="protein sequence ID" value="ADD44104"/>
        <property type="gene ID" value="Snas_4459"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4459"/>
    <dbReference type="eggNOG" id="COG0638">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040524_0_1_11"/>
    <dbReference type="OMA" id="CVSQRAE"/>
    <dbReference type="OrthoDB" id="537546at2"/>
    <dbReference type="UniPathway" id="UPA00997"/>
    <dbReference type="UniPathway" id="UPA00998"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019787">
        <property type="term" value="F:ubiquitin-like protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019941">
        <property type="term" value="P:modification-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070490">
        <property type="term" value="P:protein pupylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02111">
        <property type="entry name" value="Pup_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022279">
        <property type="entry name" value="Pup_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004347">
        <property type="entry name" value="Pup_ligase/deamidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42307">
        <property type="entry name" value="PTHR42307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03136">
        <property type="entry name" value="Pup_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018077">
        <property type="entry name" value="UCP018077"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03686">
        <property type="entry name" value="pupylate_PafA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2 3">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR018077-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="452" mass="51845" checksum="2DAF6751EC3CA3A9" modified="2010-04-20" version="1">MDRRIFGLETEFGVTCTFRGQRRLSPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATPECDSVADLVRHDRAGERVLEGLLIDAERRLHDEGIAGDIFLFKNNTDSAGNSYGCHENFLVSRHGEFGRLADILIPFLVTRQLICGAGKVLQTPRGALYCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAERYRRLHVIVGDSNMNEVTTMLKVGAADLVLKMIETGVTMRDLTLENPIRAIREVSHDITGRHKVRLANGREMNALEIQQEYLSKAVDFVERRGADAVTKRVIELWGRVLSSVENGDLDSISREIDWVSKYQLIEKYRAKRDLPLSSSRVAQLDLAYHDIRRGRGLYNLMERRGSVDRVVRDVETFEAKEVPPQTTRARLRGEFIRRAQEKRRDFTVDWVHLKLNDQAQRTVLCKDPFRSRDERVDKLIASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q563</accession>
    <name>D3Q563_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4467</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019683.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4467"/>
    <dbReference type="EnsemblBacteria" id="ADD44112">
        <property type="protein sequence ID" value="ADD44112"/>
        <property type="gene ID" value="Snas_4467"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4467"/>
    <dbReference type="eggNOG" id="ENOG502ZYGE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_665298_0_0_11"/>
    <dbReference type="OMA" id="VYNEDWF"/>
    <dbReference type="OrthoDB" id="1095437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="376" mass="41785" checksum="807D37E7262ECA91" modified="2010-04-20" version="1">MLTTHHGSHAALVTNIDAADVVPGELDAIIVPTVRPGWHLTSALEVAAELDRPLLCLSSKGSDPADILKVADSVGAEAIVIDTTEALPKLLPDFATTKLIRERGFGRSTDLSGKRNLGLLIARAMNWRKILFLDDDIRQVTARDLRALGRLLDSFAAVGLGNTGYPDNSVVCHAFRAVDGQQDTFVSGGLLSVRADRLDGFFPDIYNEDWFFLHSTRDIARTGAAFQDRYDPFVTPNRATDEELGDCLAEGVYWLRDEGKSPATAREEAFWSHYLDGRRQLIDEVRQRLETKPADEEGLRERQLASMAAARDVHRRITSELCTAIIRAWESDTADWRGHRAQTPAGTSVEDCLRLLEKRHHPGSGIDWDARVHRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5T8</accession>
    <name>D3Q5T8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0522</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
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            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="Snas_0522"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="Proteomes" id="UP000000844">
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    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:exonuclease activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
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        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
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    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048256" evidence="1">
        <location>
            <begin position="29"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="54"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="305" mass="33301" checksum="6BBAD24FF3613CB2" modified="2010-04-20" version="1">MSSPTFRRRTLLGATVAAAALSGGTGFAATAHAGTRAKEEPLIGPATGEQLHVMTFNVRWDTDPSPHSWAERRILIKELLGRERPTILGTQEGLLHQGQHLLADQKGYDWVHLSRRGGGEDEATAVLYDTSRLRVTNYGHLWHSDTPQSMGSTTWGNEIPRMMTWLRFTDSASDKEFVLVNTHLDHKSAPSREKSAAQIKELVASFDVPVLVTGDFNTAQGTAPYTTLVDGTTLEDTWETAEQQLTPAYGTFNGWKPEPVDGGDRIDWVLATPGTAVAKTAVNTWSVDGLTPSDHWAVQSLVTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5V0</accession>
    <name>D3Q5V0_STANL</name>
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        <submittedName>
            <fullName evidence="10">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_0535</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
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    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
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                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ADD40249">
        <property type="protein sequence ID" value="ADD40249"/>
        <property type="gene ID" value="Snas_0535"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_11"/>
    <dbReference type="OMA" id="AFTYLVQ"/>
    <dbReference type="OrthoDB" id="643917at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="18"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="337"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="371"/>
            <end position="378"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ADD40249.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="569" mass="59541" checksum="7F5C06D08AAD6A3C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5V5</accession>
    <name>D3Q5V5_STANL</name>
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        <submittedName>
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        </submittedName>
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    </gene>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
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            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
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            <end position="84"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="3">
        <location>
            <begin position="228"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="453" mass="47694" checksum="837C21DB4632C054" modified="2010-04-20" version="1">MAVTARFPAPGGRSTPSFRKGSYPCGRRRRLITEGEDDRRNHPYRELVSTRIAGLPWSWRPSRRAAIAASAILAVATTVAALAHVSHFEPPGAQPWIDYALALAGSLPLALLYRRPLAVCSIVVASDLAVWFFRPSWTMAGALVLPVVIYAATSRHGRPVAAVSWLVCATGLATATAVVAPVFLADGTWVVVALLAAVGAIAGDAAHARRRWHAHDRAARQRRAALEERLRLSRDLHDVVGHHLTAIALQADAATRRLQHDAAAHAGASEPTPTPADPASADAVTSSIPPAANHFAVVADTARTALAETRRLIAYLRQGTDHPTADQPGIDELPQLIAEALRDGLIVDLHTTAPAAVPPAIGLAAYRVVQEALTNVRKHSGAPTARVEISGPPELLTIRVADSGPAAEATTRTGFGLTGLRERVEAQGGQLLAGPRDSGGFEVLASIPLTSGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q621</accession>
    <name>D3Q621_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017767.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2514"/>
    <dbReference type="EnsemblBacteria" id="ADD42196">
        <property type="protein sequence ID" value="ADD42196"/>
        <property type="gene ID" value="Snas_2514"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2514"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_5_11"/>
    <dbReference type="OMA" id="EPQATRW"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="7"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="391" mass="41656" checksum="2FB5624619305D69" modified="2010-04-20" version="1">MSAPRRVVIVGAGIGGLASAIALERAGWRVALLERGDRLRGDSNALTLLPNAITALKELGLGIALDAIATPMTSGRFRRADGRVLSEIPVAELTERFGTPPVVVHREDLFEALVAAMGTGVEVHTGVTATHIDLVHTAAGDTSRRWPADLVVGADGIASAVRVGMTSGSKITNSGTVAFRAVIPRHRTPDMPEGGGETQGPDGRRFLYAPMGKRGAYWAAITRGGLRPEPEEVRKDLIARWFADWHAPVGELIANTRPEEISQREITYLWPLPRRYTHIGDTSGAVLVGDAAHAMTPDLIQGAGMALEDAVTLGACLTGASIPDGLARYEELRHARTVKLAKLAHRVGSVFGARGRLKSTVRDGLMRAAPDTWLAKQAMTGVDWVPPKPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6F1</accession>
    <name>D3Q6F1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiosulfate sulfurtransferase</fullName>
            <ecNumber evidence="2">2.8.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4550</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>hydrogen cyanide + thiosulfate = 2 H(+) + sulfite + thiocyanate</text>
            <dbReference type="Rhea" id="RHEA:16881"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:18022"/>
            <dbReference type="ChEBI" id="CHEBI:18407"/>
            <dbReference type="ChEBI" id="CHEBI:33542"/>
            <dbReference type="EC" id="2.8.1.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.8.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4550"/>
    <dbReference type="EnsemblBacteria" id="ADD44194">
        <property type="protein sequence ID" value="ADD44194"/>
        <property type="gene ID" value="Snas_4550"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4550"/>
    <dbReference type="eggNOG" id="COG0117">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2897">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_655381_0_0_11"/>
    <dbReference type="OMA" id="HIPRSKC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045078">
        <property type="entry name" value="TST/MPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364">
        <property type="entry name" value="PTHR11364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00380">
        <property type="entry name" value="RHODANESE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="162"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="307"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="419" mass="43891" checksum="EF73194B06DFB242" modified="2010-04-20" version="1">MADEHWLRQAIALAAKCPPSDTAFSVGAVIVADGRVLATGYSRETDPHDHAEEAALSKLDQDLSGATVYSSLEPCGQRASRPVSCAELIIAARVPRVVYAWREPDTFVQPKGLRLLAEARVELVQLSHLAEAAAAPNAHLLLSATMSPMPLMTAGQLRELLETQAPTVLDVRWSLAAGADRDGYQAGHLPGAVFLDLDADLCGPPGPGGRHPLPEPDALRAVLRSAGVTRTGPVVVYDGGDMLAAARTWWTLRWAGVQDVRVLDGGFAAWQAEGGPVTAETSDVAASDFDVTPGGLPELDSAAAAALARTGTLLDVRTPERYRGETEPIDPVAGHIPAAVNAPAGDTMAPDHGFRAPGELAETYRRFDGEVGVYCGSGVTAARTALAMTAAGLDTPAVYIGSWSHWVADPARPVALGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6R2</accession>
    <name>D3Q6R2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4662</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019876.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4662"/>
    <dbReference type="EnsemblBacteria" id="ADD44305">
        <property type="protein sequence ID" value="ADD44305"/>
        <property type="gene ID" value="Snas_4662"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4662"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="HISRAMT"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="148"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="23687" checksum="E3CD687EAFC41F60" modified="2010-04-20" version="1">MTRVLLADDQPLIRAGFRVLLDAEDDIDVVGEASTGAEAVDLARETVPDIALVDVQMPEMDGIEATRRIAADPALSSVRVVILTNYALDEYIFDALRAGASGFLVKDTEPEELIRAVRTVAVGEALLAPNVTRRLIAEFAATPRVDGPAPLVSALTPREREVVTLVGQGKSNEEISRLLHISHTTAKTHVSRAMTKLGSRDRAQLVVAAYESGLVVPRASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6U8</accession>
    <name>D3Q6U8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0633"/>
    <dbReference type="EnsemblBacteria" id="ADD40347">
        <property type="protein sequence ID" value="ADD40347"/>
        <property type="gene ID" value="Snas_0633"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0633"/>
    <dbReference type="HOGENOM" id="CLU_2107516_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="115" mass="12499" checksum="0324D63F830F2000" modified="2010-04-20" version="1">MMEKQAFEMPVFGGDLVRTQRRRFTTPDGTNAGWLIVNAADQFTEIFDDVAAALASATDLSLDALAVHDDLRASLPHQLRRVPGACCPVPGCTHHHGDLGDNSDDPPQHAVPQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6W9</accession>
    <name>D3Q6W9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0655</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015939.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0655"/>
    <dbReference type="EnsemblBacteria" id="ADD40368">
        <property type="protein sequence ID" value="ADD40368"/>
        <property type="gene ID" value="Snas_0655"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0655"/>
    <dbReference type="eggNOG" id="COG1172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028880_2_2_11"/>
    <dbReference type="OMA" id="DWFKAFL"/>
    <dbReference type="OrthoDB" id="1254678at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="350" mass="37238" checksum="08F863EC6F9C43C7" modified="2010-04-20" version="1">MSQTTSVAAEIDPVASQVSRRPALLRLLTRPEFGSLVGAIAVFAVFYALAPTFRNASSWSTILYETSTIGIMAVAVALLMIGGEFDLSAGVGVIATALFGAIFTYQLSVNVWVGVFASLAFGLAVGFVNGWLLVRTKLPSFLVTLSTFLMLQGLNVALTKLITGSTASDRISDMDGFAAAEAVFASEFSLFGVDIQITVLWWLLFVGLATWVLLRTRVGNWIYASGGDADSARAVGVPVNRVKIGLFMVMGAAAWFSGMHLLFEYNTVQSGEGIGNELLYIMAAVIGGCLLTGGYGTAVGAAIGALIYGMTKQGIVYAGWDDNWLMFFVGAMLLLATVINAWVRRQAGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6X8</accession>
    <name>D3Q6X8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0664</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015948.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0664"/>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40377">
        <property type="protein sequence ID" value="ADD40377"/>
        <property type="gene ID" value="Snas_0664"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0664"/>
    <dbReference type="eggNOG" id="COG2730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027657_1_0_11"/>
    <dbReference type="OMA" id="DCNSIDW"/>
    <dbReference type="OrthoDB" id="1395441at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901136">
        <property type="term" value="P:carbohydrate derivative catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041036">
        <property type="entry name" value="GH5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18564">
        <property type="entry name" value="Glyco_hydro_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cellulase" evidence="4">
        <location>
            <begin position="50"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_5_C" evidence="5">
        <location>
            <begin position="388"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="470" mass="51613" checksum="1BED9DDD91424F00" modified="2010-04-20" version="1">MRRARWFGVLFAVVILLVGGLASVVRGQPESRVPRFITDDEGRALILHGLNTASSAKSTPDAMPDLSEDDVEREYRDMGTNFVRFLIQWRAVEPRPGEYDEDYLDKVAERVSWYEKRGYHVMLDMHQDLYGPGVTAKGDVGNGAPRWATETDGLPVSAQEQWELYYLEPGVVRAFDNFWGAASDATLMRHYAKAWGEVADRFADADAVLGYDLMNEPWGGSVQGAAFESGPLAELYRLSIDEIRDVDADSWIFLEPQAVGVNWGLPSALPAVDDPRRGENRIAFAPHLYPLPMDLGDDYATVKGEVDAAMTTWSDNVLRTAQRLDAPVVLGEFGLDATRPGALDYVESVADLADATGMGWSYWSNDPGGWGPYDEDGKASPLVKTLDRAYPRAVAGTPTAIDSDADSLTLTFRGDPDVKAPTEIYLPRGFGDGGELDCDGCQSDWDADRRVLSVATVADDEQHTITVTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Y5</accession>
    <name>D3Q6Y5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015955.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0671"/>
    <dbReference type="EnsemblBacteria" id="ADD40384">
        <property type="protein sequence ID" value="ADD40384"/>
        <property type="gene ID" value="Snas_0671"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0671"/>
    <dbReference type="HOGENOM" id="CLU_2358331_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="96" mass="10152" checksum="4817783ED5AB6322" modified="2010-04-20" version="1">MGGPLDGIKIAPDKVIAFSNEVTRTGTSIDGTAAKIPKIKIDIAELESAKALETLSSNWSHNARQLAIKVDHAALAINRAARGHKTDDDTGAKAYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7L5</accession>
    <name>D3Q7L5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019928.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4714"/>
    <dbReference type="EnsemblBacteria" id="ADD44357">
        <property type="protein sequence ID" value="ADD44357"/>
        <property type="gene ID" value="Snas_4714"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4714"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069431_0_0_11"/>
    <dbReference type="OMA" id="YAVYVEP"/>
    <dbReference type="OrthoDB" id="1175268at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="249" mass="27766" checksum="A8DF32520C5266B8" modified="2010-04-20" version="1">MSLTITTLAERPELTGAFWELRDNWPRYITEDRVSWFHYGAILTTFPEYVLVATDADGQLVARALSVPFKLDLEGRRELPSGGWDQALLWAFSDHRASREPDVVSAIEISVDNRHLGRGLSREVLASMRDNARARGFAELVAPLRPTGKHLEPDAPMSEYAWRTREDGLPHDPWIRTHVRAGAVIDSVASTSMVVTGSLADWRTWTGLPFDTSGPVVVPSGLNPAQCYVEADYAVYVEPNVWVRHALTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7U8</accession>
    <name>D3Q7U8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0741</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016024.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0741"/>
    <dbReference type="EnsemblBacteria" id="ADD40453">
        <property type="protein sequence ID" value="ADD40453"/>
        <property type="gene ID" value="Snas_0741"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0741"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_926794_0_0_11"/>
    <dbReference type="OMA" id="AGPYFNL"/>
    <dbReference type="OrthoDB" id="1452155at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="27"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="286" mass="30187" checksum="CD9D09DC0AE081E0" modified="2010-04-20" version="1">MSKRVSVRKTYKLYVGGKFPRSESGRTYLVTASDGSLLANAARASRKDVRDAVAAARKAQPGWAGATAYLRGQITYRVAEMVEGRRGQFIEELRNSGATIKAAEAEVDATVDRLVWYAGWADKLPQVLGGANPVAGPFFNHSTPEPVGVAAMVAPQNDALLGLVSVIAPAIVTGNTVVVLASQDRPLPAVALAEALATSDVPGGVVNILTGQVAELTPWFASHADVNAVDLCGVADADLARDAETAAAETLTRVLRPANPDWNADPGLDRLRRFVEIKTVWHPAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q805</accession>
    <name>D3Q805_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0798</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016081.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0798"/>
    <dbReference type="EnsemblBacteria" id="ADD40510">
        <property type="protein sequence ID" value="ADD40510"/>
        <property type="gene ID" value="Snas_0798"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0798"/>
    <dbReference type="eggNOG" id="COG0154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_0_0_11"/>
    <dbReference type="OMA" id="NIFIRIW"/>
    <dbReference type="OrthoDB" id="1239251at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="22"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="424" mass="44676" checksum="D246AC236A93CE89" modified="2010-04-20" version="1">MTELVRLRPLDATPRDAVAEAEYTCDRIEATDAEIFAFESEPDRRGRLLAEAQATEERWGEPADRPALYGVPVGVKDVIHVDGLETRAGSKVPAEALAGAQATLVDRLVGAGALIAGKNTCAEFAISAPGPTRNPHNPTHTPGGSSSGSAAAVAAGQVRLSIGTQTVSSTIRPAAYCGIVGFKPSHGRIPVDGVIANAPSLDTIGILTTDVAGAAIASEVLCDEWSPRAVDELPVLGIPADEYLECASKPTLARFAEHVAKLKAAGYRVVPGRAVTDFPRIRAVLFTIQRYESAIVHAAWFDSYRALYQPKSAQSVLEGRDIDEDKHQLALKLRTAIHDQIRDMMERSGVDIWIGPSATDTAPVGLASTGNSIMSIPWSLTGMPSLSVPAPAPDLPLGFHCAARTGDDERLLAWGGDIAATLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q810</accession>
    <name>D3Q810_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_0803</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016086.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0803"/>
    <dbReference type="EnsemblBacteria" id="ADD40515">
        <property type="protein sequence ID" value="ADD40515"/>
        <property type="gene ID" value="Snas_0803"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0803"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_306068_0_0_11"/>
    <dbReference type="OMA" id="PGSEGIM"/>
    <dbReference type="OrthoDB" id="439332at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r2" evidence="7">
        <location>
            <begin position="42"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="8">
        <location>
            <begin position="139"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="zf-HC2" evidence="9">
        <location>
            <begin position="206"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="337"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="402"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD40515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="831" mass="87595" checksum="50B1A40DA4E92C20" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q888</accession>
    <name>D3Q888_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epoxide hydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2786</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018033.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2786"/>
    <dbReference type="EnsemblBacteria" id="ADD42462">
        <property type="protein sequence ID" value="ADD42462"/>
        <property type="gene ID" value="Snas_2786"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2786"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_1_11"/>
    <dbReference type="OMA" id="FESDHAS"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033961">
        <property type="term" value="F:cis-stilbene-oxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EHN" evidence="4">
        <location>
            <begin position="6"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="383" mass="42535" checksum="CE2EC6658B501685" modified="2010-04-20" version="1">MLTGMEPFRINISQSDLDDLNTRIDATRWPAAYPGAAWSRGVPLSYLRRITEYWRHEYSWRAAEAKLNEFPQFTTEIDGHNIHFLHVTSPHPDAIPLLLTHGWPGSIVEFTGIIGPLTDPKAHGADGPAFHLVIPSLPGYGFSGPSPDEGWTTRRIAKAWAELMSRLGYDRYVAQGGDRGVGVTRDLGIVDPEHVAAVHVNGGFTFPGGADPDDETLSERERIRVRRMQEFMSESGAYLALHSSRPYSVAYAFNDSPVGLLAWIIERFKDWSDPAKQLPEDAVDLDQLLTNVCVYWFTQTAGSAANAYYEDAVSGAGWGPKEPSTVPAGVAQFTTQDIALRRDDEAANNIVHWAEYFRGGHFAAMEAPDLLVADLREFFGRHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q895</accession>
    <name>D3Q895_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hemerythrin HHE cation binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2793</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018040.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2793"/>
    <dbReference type="EnsemblBacteria" id="ADD42469">
        <property type="protein sequence ID" value="ADD42469"/>
        <property type="gene ID" value="Snas_2793"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2793"/>
    <dbReference type="eggNOG" id="COG5592">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079417_2_2_11"/>
    <dbReference type="OMA" id="IESHMDH"/>
    <dbReference type="OrthoDB" id="1701106at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="2">
        <location>
            <begin position="10"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="21116" checksum="4C2C51A0114E222F" modified="2010-04-20" version="1">MVTKTDTNLISVVIADHRHIEGVFKELLNPATPHPRRQRLLEHVIGELVRHATAEERYLYPLARELLVDGDEAVDRELAEHVEAEAVMRNLERLDVADPRFLPHLENLIRIIRHHVGEEERVLLPKLDRAGEDSQLRELGLKMLRSKETASTVPHPDATDQPSADHLVDTGAGYVNRLRDHLTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8A6</accession>
    <name>D3Q8A6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidoglycan-binding domain 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2804</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2804"/>
    <dbReference type="EnsemblBacteria" id="ADD42480">
        <property type="protein sequence ID" value="ADD42480"/>
        <property type="gene ID" value="Snas_2804"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2804"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_760561_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048938" evidence="1">
        <location>
            <begin position="42"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="232"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="305"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="364" mass="40043" checksum="1DA3DDCD72B6EEC8" modified="2010-04-20" version="1">MTDKSPNTRRWFTRRRGVVLSTVAAAAAAAVTVTLVGSAGAEPPEVPEFTTPVDDYQAEDTQTTCDPTPKPGVEDFRDLILESYPDTSDAGIGRDCDPKSVKKIEHYEGDTSEHYEGRAWDWKVDAATQREQADEVFDWLLKTRDGEAHALLRRLGVMYIIFDKKILGAYNVDEGWRDYNGSNPHTDHVHFSFGWDGANQETSWWTGRGEPTFCEKANLDFKKYPALKDGDSGDEVTAAQCLLDKSGRPTTDGDPNGEYDKATAKSVKQFQADIGLKETGEIDSHTWTALLGRGSNVQLQEGEEGRNVSRLQRALTAALETTVPIDGKFTAETTAAAKKYQEKAGLDADGIVGVNTWRALRAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8G4</accession>
    <name>D3Q8G4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2863</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2863"/>
    <dbReference type="EnsemblBacteria" id="ADD42538">
        <property type="protein sequence ID" value="ADD42538"/>
        <property type="gene ID" value="Snas_2863"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2863"/>
    <dbReference type="HOGENOM" id="CLU_2195325_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="108" mass="11584" checksum="D5AD8CBC5471216D" modified="2010-04-20" version="1">MAEVLAKPVKLAQLSQDLTTISGEVRKGLSSTRESGLIDSSAYGNSTGVEAVANAYNSVFEKGGTAVEDLTEVLEGDIDRVLRMAFSYQETDEKNAEKIPECRPGKPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8L2</accession>
    <name>D3Q8L2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4813"/>
    <dbReference type="EnsemblBacteria" id="ADD44454">
        <property type="protein sequence ID" value="ADD44454"/>
        <property type="gene ID" value="Snas_4813"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4813"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_59_0_11"/>
    <dbReference type="OMA" id="THWAHCQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="218"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="325" mass="34786" checksum="AEDC5543099EBCF6" modified="2010-04-20" version="1">MNERLVAVVGYDDAMLLDIACVTSTLAAANRAGADPPYRTVLAAPGGNPVRCDSGQTLHAQASLEKLTGPFDTLVVSGGWGHDSAAADRRIVAHVRRLARESRRVASVCTGADILAAAGLLDGKRATTHWYFADRLAAAHPTVTIDPAPIFVRDGSVFTAAGVTSALDLTLALVEDDNGPDLARFTSRVLVTYLQRPADQAQMSVYVAAPATTHPLLRKVCEHITSHPDADLSTTELARRARVSQRQLTRLFTEHTGQTPGRYVREARLAAAARLLDTSGLSVTAVATRSGFSSAEALRQPFTRRYGLSPTAFRAAHTRRPNRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8M0</accession>
    <name>D3Q8M0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4821</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44462">
        <property type="protein sequence ID" value="ADD44462"/>
        <property type="gene ID" value="Snas_4821"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4821"/>
    <dbReference type="HOGENOM" id="CLU_2358335_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="96" mass="10017" checksum="87A28E8AC8CD360B" modified="2010-04-20" version="1">MSDMRQKPLRSSRQAHPLAVAATLATGIMVVGGAGFALAVNDLARWVVVVAAVGAILTAWTEGRHVAATKKQIASLGIAPRPRTPADDNPQFFAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8M1</accession>
    <name>D3Q8M1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamine synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4822</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020034.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4822"/>
    <dbReference type="EnsemblBacteria" id="ADD44463">
        <property type="protein sequence ID" value="ADD44463"/>
        <property type="gene ID" value="Snas_4822"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4822"/>
    <dbReference type="eggNOG" id="COG0174">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017290_1_3_11"/>
    <dbReference type="OMA" id="TFYTHPE"/>
    <dbReference type="OrthoDB" id="416474at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="4">
        <location>
            <begin position="105"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="448" mass="49996" checksum="A7385B7A09A92D5C" modified="2010-04-20" version="1">MERQQEFVLRTLEERDIRFVRLWFTDVLGTLKSVSVAPAELESAFDEGVGFDGSAVEGFARVYESDMVAMPDATTFQVFPFEGTGIGESARIFCDIVTPDGAPSWADPRHVLRRALARAADAGFTYYTHPEIEFFLFEDPVKGKPPVPVDEGGYFDNTTHAVARDFRRQAILALERIGISVEFSHHEVAPGQQEIDLRYADAMATADNIMTFRHVVKEVALSAGVQASFMPKPFTDQPGSGMHTHLSLFEGEDNAFHDPSDDIKLSKTGKAFIAGLLKHAPEYTAITNQWVNSYKRLFSMPLANRVNEAPAYVCWGHRNRSALVRVPAYGKPNSARVEVRSLDSATNPYLAFAVMLGAGLRGIEQGYELPPGTEDDVWALTDRERRAAGYRQLPANLAEAIDAMADSELVAEVLGEQVFDFFLKNKQAEWDDYRCQVSAYELNRYQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Y9</accession>
    <name>D3Q8Y9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0887"/>
    <dbReference type="EnsemblBacteria" id="ADD40598">
        <property type="protein sequence ID" value="ADD40598"/>
        <property type="gene ID" value="Snas_0887"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0887"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089258_4_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="15"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="23883" checksum="F611CB3B7DD22C5C" modified="2010-04-20" version="1">MARRSAASYQLSLAVLAYLMEKPRHPYELGKVVRERNGQESIDYKHASLYMVIDQLRRDGHIEAFETVRDGQRPERTVYRLTDSGRAELRDRMRTQIATPAKEHRMFEGVLSLVAALAPEEVDELLTERATALAAQIARIHEHVDDDPSIHRLFHIEHEYRLGQLEAEATFVREFQQLIRDNTENFTTFWTDLRARVLTAQSEPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q946</accession>
    <name>D3Q946_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0944</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016226.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0944"/>
    <dbReference type="EnsemblBacteria" id="ADD40655">
        <property type="protein sequence ID" value="ADD40655"/>
        <property type="gene ID" value="Snas_0944"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0944"/>
    <dbReference type="eggNOG" id="COG4976">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1140672_0_0_11"/>
    <dbReference type="OMA" id="HDFACGT"/>
    <dbReference type="OrthoDB" id="1424160at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="245" mass="27314" checksum="E8045AD91BA0F2ED" modified="2010-04-20" version="1">MRTDYTDVFRDSAAVDKYADEVYANGTFSSVVSERQRQWLRGFITEAFDDAPEHHDFACGTGRVARMLDGLVRTSHGYDTSEAMLAKAHALGTPGQLHVIDEDGPLPTSDSRPTLVTMFRLLLNVSDAVRDRALDFAAGMLPDADSGLLVCENHGNARSLRHLRKALGPGETDWFNELSRAEVERLFDRHGFELVTTQGFSLLTQGFYRHAPLKWVAPSLDGLLARTRLGTAFATDVLYVARRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q970</accession>
    <name>D3Q970_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016250.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0969"/>
    <dbReference type="EnsemblBacteria" id="ADD40679">
        <property type="protein sequence ID" value="ADD40679"/>
        <property type="gene ID" value="Snas_0969"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0969"/>
    <dbReference type="HOGENOM" id="CLU_2195323_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="108" mass="11130" checksum="D66A410BB0135B58" modified="2010-04-20" version="1">MTISLIFAGLGIAFSVLGAALSIRTSRRSEDVDTEGASEETGPAPKLSGSLNAAADQLEDAIDVFAAEYGQHHPADVNGEAARRVFARLATVTSDLKALRGNGSVVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9F7</accession>
    <name>D3Q9F7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018210.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2964"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42639">
        <property type="protein sequence ID" value="ADD42639"/>
        <property type="gene ID" value="Snas_2964"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2964"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020629_1_0_11"/>
    <dbReference type="OMA" id="PFYWDKT"/>
    <dbReference type="OrthoDB" id="724641at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="350"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="476" mass="53387" checksum="1BCF880233C5E2F4" modified="2010-04-20" version="1">MTDVDTREFSARTLFSRGQRITLTVIAAAIAIPLGLNLTLGIGPEPLWWGRMAIAATVVLYLAVIGFKLAMIAGSGRSSALHFDPGSLTVIADAALPPYTVLVPLYREATVLPTLVSRLSALDYPRDRLQILLLIEADDAETLDAAVTCATDPRFEIVVIPDSVPKTKPKACNIGLARAVGEFCVIYDAEDRPDPDQLRKAALAFRLSPQRVVCVQAELQYWNPWTNWLTRCFAAEYATNFSMTLHGMDRYRLAIPLGGTSNHFRTDALRALGGWDPYNVTEDADLGIRIARRGWDVRMMVSVTEEEANARLGNWLRQRSRWIKGYLQTWLVHSRRPYRLWREVGTRRSLAVHLTLGFATVTTLVNPVMWAMTILYLIVGPQPLEPLFPKYNLYGGVIAMLLGNALMCYTLMLGCVRRGLFAAVRVMLTIPLYWGLMSLAAYKALIQLLRPSKRHYWELTEHGLVRSEDTVETHNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9I5</accession>
    <name>D3Q9I5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2993</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018238.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42667">
        <property type="protein sequence ID" value="ADD42667"/>
        <property type="gene ID" value="Snas_2993"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2993"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_4_11"/>
    <dbReference type="OMA" id="GHRHVRH"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048972" evidence="2">
        <location>
            <begin position="31"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="184" mass="20125" checksum="34DD1BDCD449CB1F" modified="2010-04-20" version="1">MCANPPVTLTADAVATTPALLLRPWHPADAAALATAHDDPDMRRTLMFPLDGIAEARDWIGRQVESWNAGTRHSFAVLGADDERILGHVVVKMVSDFDPAAVEVGYWTVTAARGLGVAPRAVATVTPWIFAEWDRVKRVDLLHAVDNPASCRVADKSGFRLEAELPPRPPEYPGPGHRHVRDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9S8</accession>
    <name>D3Q9S8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020195.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4987"/>
    <dbReference type="EnsemblBacteria" id="ADD44624">
        <property type="protein sequence ID" value="ADD44624"/>
        <property type="gene ID" value="Snas_4987"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4987"/>
    <dbReference type="eggNOG" id="COG2074">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092760_1_0_11"/>
    <dbReference type="OMA" id="MVRKEAM"/>
    <dbReference type="OrthoDB" id="1383055at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="278" mass="30432" checksum="A34AFB4E51EE2182" modified="2010-04-20" version="1">MRNVVWIGGGCGAGKSTLARMLAFRFDLRLYRVDSFAYPHQRRIDPVRHPQMARLAALSHTERFVDPSPAQLAADFTAYAHEAFAMVLDDLAALADGPLVIAEGPSLLPELVAPVAASAGHTIWLLPTSEFTDRNLSRRFDPHKDDPDAKRRHDNRIGRDRLLTEAMRASASKHGLPVLDVDGSLSLEQTADRLSEHFADVLAAGPRARDGAERSRLRRAENTETHTAVTMFLESLGDAAPEDPPPVTFACECETLGCQAEVALPPSRYPSLDDVIAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA29</accession>
    <name>D3QA29_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016312.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1031"/>
    <dbReference type="EnsemblBacteria" id="ADD40741">
        <property type="protein sequence ID" value="ADD40741"/>
        <property type="gene ID" value="Snas_1031"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1031"/>
    <dbReference type="eggNOG" id="ENOG5032Y6I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_154652_1_0_11"/>
    <dbReference type="OMA" id="MCTAPKQ"/>
    <dbReference type="OrthoDB" id="1774182at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010814">
        <property type="entry name" value="DUF1416"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07210">
        <property type="entry name" value="DUF1416"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="112" mass="11369" checksum="C079F90F3C0BE7E8" modified="2010-04-20" version="1">MGTNTSNTLTAAGCGAPDQSAALPAAINLETETVITGSVKSATGDAVEGAYVRLLDGDGEFTAEVVTGDGGAFRFFAADGEWTLRALSREGDGETAVQASRGLNEVTVSVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA99</accession>
    <name>D3QA99_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1101"/>
    <dbReference type="EnsemblBacteria" id="ADD40811">
        <property type="protein sequence ID" value="ADD40811"/>
        <property type="gene ID" value="Snas_1101"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1101"/>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1288238_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="214" mass="24168" checksum="D41728EEFBA96046" modified="2010-04-20" version="1">MIDIEEMPQRVVGDGVTAVCWIEDAALSDEDELALRRFVGRFPSLRFARDTPAVLDRHETVDQVTLPAWFRVARTILAGLEPAGRVRLDAFAIDGSPRETPREYYEISPGYINEEIRGLLFDKAGVYLIGQEFGDDESCLAIDLENPRDRRIFEFAMEDLLDDDIADRPLRKSLTPVFSSYADLLGHIVAARMPDGEIVIAADQGRWGDVRWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAD5</accession>
    <name>D3QAD5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3047</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018289.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3047"/>
    <dbReference type="EnsemblBacteria" id="ADD42718">
        <property type="protein sequence ID" value="ADD42718"/>
        <property type="gene ID" value="Snas_3047"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3047"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="ETRRPWW"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="13"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="105"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="169" mass="19575" checksum="2D91361B5BC9FD36" modified="2010-04-20" version="1">MKPEAEAEYREFVSARLDQLGRFAFLLCRDWHRAEDAVQKGLVKLYLHWDKTTIKSPDAYVRQVIVNVVREEARRHWFKRERSSDRLPERHHPDPGEAGSERLTMLDALSRLPKRQRIAVVLRIWEDLSVEQTAEIMACSPGTVKSQTARGLQTLRGLLSETIPEEVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAG9</accession>
    <name>D3QAG9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018323.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3081"/>
    <dbReference type="EnsemblBacteria" id="ADD42752">
        <property type="protein sequence ID" value="ADD42752"/>
        <property type="gene ID" value="Snas_3081"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3081"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103702_3_0_11"/>
    <dbReference type="OMA" id="EHYARLM"/>
    <dbReference type="OrthoDB" id="1859598at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="107" mass="12032" checksum="10367D78CCA8B1B7" modified="2010-04-20" version="1">MDLAMRYDTGKLFFDARDFITAAGWLAEVVDAEPGHEAARMLLARAYYHSAQLGRAESQLREIIERNPVEAYAYLMLGRTLQRQGRDDEAVRYMRLSAAMTGGSLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB74</accession>
    <name>D3QB74_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsG</name>
        <name evidence="10" type="ordered locus">Snas_1181</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016462.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1181"/>
    <dbReference type="EnsemblBacteria" id="ADD40891">
        <property type="protein sequence ID" value="ADD40891"/>
        <property type="gene ID" value="Snas_1181"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1181"/>
    <dbReference type="eggNOG" id="COG0049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072226_1_1_11"/>
    <dbReference type="OMA" id="NVMPHVE"/>
    <dbReference type="OrthoDB" id="1540940at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_S7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S7" evidence="9">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD40891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="156" mass="17782" checksum="4AC4084BA685CFEB" modified="2010-04-20" version="1">MPRKGPAPRRQLTADPVYNSMLVTQLINKVLVRGKRQLAERIVYSALEGTRAKTETDPVVTLKRALDNVKPTLEVRSRRVGGATYQVPVDVRPSRATTLGLRWLVDYSRARREKTMIERLMNEILDASNGLGAAVKRREDTHKMAEANRAFAHYRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBI7</accession>
    <name>D3QBI7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3199</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018440.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3199"/>
    <dbReference type="EnsemblBacteria" id="ADD42869">
        <property type="protein sequence ID" value="ADD42869"/>
        <property type="gene ID" value="Snas_3199"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3199"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="RDICHER"/>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="319" mass="33115" checksum="36204B9E1016BA89" modified="2010-04-20" version="1">MPGLVFEDVHVTYPGGVRAVRGVSLEVASGRRVGVAGESGCGKSSVALAALRLLPASAEVSGRILIDDEDVAGMSWGRLRAVRWTGASIVFQGAMHALNPVRTVGHQIAEPLILHDKLSPKAAAGRVGGLLERVGLPGWRAGSFPHQLSGGQRQRVMIAMALACRPGLIIADEATTALDVMIEAQVLRLLDQIVADDRIALLMISHDVSVLSAWCDELAVMYAGRIVEHGPAKAVVQAPSHPYVRGLVGALSPVGDVGARLSPHGLAGRAPDPAGLPRGCAFRARCDVAVEECASLDVGLRSSGEGRVAACVHVGGESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBQ7</accession>
    <name>D3QBQ7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcriptional regulator WhiB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">whiB</name>
        <name evidence="13" type="ordered locus">Snas_5161</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">The Fe-S cluster can be nitrosylated by nitric oxide (NO).</text>
    </comment>
    <comment type="PTM">
        <text evidence="11">Upon Fe-S cluster removal intramolecular disulfide bonds are formed.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the WhiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020367.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5161"/>
    <dbReference type="EnsemblBacteria" id="ADD44796">
        <property type="protein sequence ID" value="ADD44796"/>
        <property type="gene ID" value="Snas_5161"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5161"/>
    <dbReference type="eggNOG" id="ENOG5032RSG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106245_6_2_11"/>
    <dbReference type="OMA" id="DTCLKWA"/>
    <dbReference type="OrthoDB" id="1944871at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035731">
        <property type="term" value="F:dinitrosyl-iron complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01479">
        <property type="entry name" value="WhiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034768">
        <property type="entry name" value="4FE4S_WBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003482">
        <property type="entry name" value="Whib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38839">
        <property type="entry name" value="PTHR38839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02467">
        <property type="entry name" value="Whib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51674">
        <property type="entry name" value="4FE4S_WBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="4Fe-4S Wbl-type" evidence="12">
        <location>
            <begin position="8"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD44796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="88" mass="9756" checksum="CDC91F8FDD8E8A95" modified="2010-04-20" version="1">MDWRHIAICRDEDPELFFPIGDSGPALVQIEQAKGVCRRCPVTEECLKWALESGQDAGIWGGMSEDERRALKRRGGIRTLSVAARTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTY2</accession>
    <name>D3PTY2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015311.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0018"/>
    <dbReference type="EnsemblBacteria" id="ADD39740">
        <property type="protein sequence ID" value="ADD39740"/>
        <property type="gene ID" value="Snas_0018"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0018"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_11"/>
    <dbReference type="OMA" id="ANCAAYD"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="330" mass="34943" checksum="BA3B8D007EF7BA8E" modified="2010-04-20" version="1">MNDGTHPDDHADEPAATDDTPTAPKPGRRYTRRRLLTTSAVAAGAAAVAVGTTAVLTNDGTPPTIKPSGRNRFDGKVVIVTGATSGIGRAAAKLFAAEGAKVGFCGRREKLGAEVEREIRSDGGEATYIRADVRKESQVRKFVDRVADEYGGLDVCFNNAGITLQKPLHEYTAAEWDDVVDTNLRGTFLCMKYEVPHLIERGGGSVVITSSSNVHSTGEERSAYTASKHGLLGLANCAAYDYAEHNIRVNTLIPGTTNTELVRRVAGAMDLPDAVWEEMAAAYGRANAPTMKRLATPEEIAVGALALASPDFSYMTAGSLTLDGGDSNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUG6</accession>
    <name>D3PUG6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_3313</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018550.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3313"/>
    <dbReference type="EnsemblBacteria" id="ADD42979">
        <property type="protein sequence ID" value="ADD42979"/>
        <property type="gene ID" value="Snas_3313"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3313"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043648_1_0_11"/>
    <dbReference type="OMA" id="RSTFRAW"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014305">
        <property type="entry name" value="RNA_pol_sigma-G_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02960">
        <property type="entry name" value="SigX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="7">
        <location>
            <begin position="23"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="8">
        <location>
            <begin position="140"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="9">
        <location>
            <begin position="217"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD42979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="341" mass="37450" checksum="06F0B86434579ED9" modified="2010-04-20" version="1">MTSETSAAVAAAQAGDEAEFGRLAQRYRPELQAHCYRMLGSVDESQDLVQETYLRAWRYRTSYQGRSTFRAWLYRIATNVCLDALSRHAPARQQAIGEAAAPAVAVPWLRPYPDRALEMLKSGELEPDAAAVSRETLELAFIAALQYLPARQRAALVLRDVLDWSAKDTASALETTVASANSALQRARATLKTQLPRQRGEWARTTELSATDRDLLHRYMDALERADTQAVAALLAADARVSHQGGAGGNLSPEPVWYQGRDTIMAAWAPILEVADAPDMRLLATSANRQPAVASYIRTGDDPLFQAFALTVLRIEDGYVQEVTTFGTDCFAAFDLPMTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUM6</accession>
    <name>D3PUM6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3375"/>
    <dbReference type="EnsemblBacteria" id="ADD43039">
        <property type="protein sequence ID" value="ADD43039"/>
        <property type="gene ID" value="Snas_3375"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3375"/>
    <dbReference type="eggNOG" id="COG0620">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_768984_0_0_11"/>
    <dbReference type="OMA" id="ERAIWIV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="345" mass="37902" checksum="857C9D78416061C2" modified="2010-04-20" version="1">MSRLVHYVGSLPPEINTSPRDGMRWIIDHSADAGLSTLPWDSDPRWIVEFLLGLAERGEALEVVQSGDWGDYDKQQRYRVKSGVKLTASHVSMRRAERIRQNLAVYRELVADDSRLDGVPFQQSLPSPLDLSLFTFGQRPVLLKHVATYADALAAEVTDLHATDGDDLVWQLEAPTVLVLLNKTPRPLRGFVARRLAAQMAGFVERLPQEARLILHLCYGNLNDRELVAPRDLAGVDVFLNALHTRLRAQNRAIPPVHVPAAYGSQPPPVRPQFYAALGSVHADWPLVAGIVDENQPDDSRKALALFEAAADRSSHAVATACGLGRHSEADARAAAALMTELSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV20</accession>
    <name>D3PV20_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016644.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1366"/>
    <dbReference type="EnsemblBacteria" id="ADD41073">
        <property type="protein sequence ID" value="ADD41073"/>
        <property type="gene ID" value="Snas_1366"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1366"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_1_3_11"/>
    <dbReference type="OMA" id="LWWDTEP"/>
    <dbReference type="OrthoDB" id="1439085at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049268" evidence="1">
        <location>
            <begin position="28"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="91"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="591" mass="63849" checksum="4E4030E79CA0CFC6" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV60</accession>
    <name>D3PV60_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PHP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1406</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016684.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1406"/>
    <dbReference type="EnsemblBacteria" id="ADD41113">
        <property type="protein sequence ID" value="ADD41113"/>
        <property type="gene ID" value="Snas_1406"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1406"/>
    <dbReference type="eggNOG" id="COG0613">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032306_1_0_11"/>
    <dbReference type="OMA" id="WIDFRRP"/>
    <dbReference type="OrthoDB" id="1309717at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="2">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="403" mass="43304" checksum="6BC196C2CC0D1B60" modified="2010-04-20" version="1">MAAETTLTGVWTPGDRAEGFYRYLPFEVPTGTNAVRVRLEYPRAGGVLDLGCFGAEGFRGWSGGARDRCEIGESAATPGYLPGELETGQWNVVLGLHRVPQPLEYTVTIATSADPVTRVEERVPVATERRPRRDLPAPTGMRWAAGDLHSHSEHSDGTLSLDALAASAASAGLDFLAVTDHNTVSHHPHLAAAGDRHGVLLLPGQEVTTERGHANAFGPLPWIDFRRPAQHWLETTEAAGGLLSVNHPIAVDCAWRQHLSRPAPLAEVWHCTWRDRTWSGPLAWWLANGTATTAIGGSDFHEPGRDRPLGQPTTWVLVPDGEPTVAAVLEALRTGTVAIAADIDGPALLRVEDELVAVAADGAILSDYSGRRRLVRGETARFPAPAGPHWLEDSRTTVLAIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV65</accession>
    <name>D3PV65_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016689.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41118">
        <property type="protein sequence ID" value="ADD41118"/>
        <property type="gene ID" value="Snas_1411"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1411"/>
    <dbReference type="eggNOG" id="COG3576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054794_1_1_11"/>
    <dbReference type="OMA" id="RITLMWC"/>
    <dbReference type="OrthoDB" id="1885467at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="9"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="200" mass="21814" checksum="8C4180752FE5122A" modified="2010-04-20" version="1">MGHVYEEINERLAAFIDEQPMFFVGTAPSGDSGHVNVSPKGMAGTFKILGPHRVAYLDWGGSGVEGTAHMRQNGRVCVMFCSFGRSPKILRLHGTGTPVLRGEPRFAELLARFDAAPDVHGVRGVIEVDVTRVSDSCGYGVPYMELKGDRTMLVDVNERRSDADIAKRRLETNTLSLDGLPGVAGTAAEARYRRKLEADH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVI8</accession>
    <name>D3PVI8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3438</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3438"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43102">
        <property type="protein sequence ID" value="ADD43102"/>
        <property type="gene ID" value="Snas_3438"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3438"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_14_4_11"/>
    <dbReference type="OMA" id="RMIDIFY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="416" mass="44405" checksum="18F3F0C314751132" modified="2010-04-20" version="1">MPNTRGRSRRELNIHIVSTYPPRRCGLANFTTDLRDALLGLDQDIDVRVCAMDTDGLTYPDEVTATISADAPATYRAAARRMRDQGADIVLIEHEYGIFGGTAGAHVLELSAELTRLGLPYMVTPHTMLSCPTRAQATVLHRLCRDAALITMLTPTGVNLGVDAGLAQPSKLVVIPHGAPPILRTSIEESRLGPDLARILAKSRTGPLLSTFGLLGPGKSLETAIDGLATVVERLPDVRYVIAGATHPGELAAHGTAYLSRLRDLACRMGLEDNVDFVDRYLSPAELSALLANTDVYLTPYRSQEQISSGTLTFAVAAGCPTVSTDYHYARDLLSSGAGRLVSGDDPAGFGAAVTELLTDPVALSCTRVVARRVGNRLMWPRVAETLVERIRSCGGDRNGTLSTVGVGDHVSRLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVJ2</accession>
    <name>D3PVJ2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SHOCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018677.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3442"/>
    <dbReference type="EnsemblBacteria" id="ADD43106">
        <property type="protein sequence ID" value="ADD43106"/>
        <property type="gene ID" value="Snas_3442"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3442"/>
    <dbReference type="eggNOG" id="COG3462">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159099_1_0_11"/>
    <dbReference type="OMA" id="PERRMMM"/>
    <dbReference type="OrthoDB" id="2068436at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018649">
        <property type="entry name" value="SHOCT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09851">
        <property type="entry name" value="SHOCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="SHOCT" evidence="2">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="82" mass="9402" checksum="18BB23686C653FFB" modified="2010-04-20" version="1">MMYWDNDMGPAAWVFMTLNHLVVWALLVGAIWLAVRAVRHYVSHGGGVTHPERVLAERFAKGEIDEAEYRERLDVLRGHARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW15</accession>
    <name>D3PW15_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mutlidrug resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5505"/>
    <dbReference type="EnsemblBacteria" id="ADD45136">
        <property type="protein sequence ID" value="ADD45136"/>
        <property type="gene ID" value="Snas_5505"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5505"/>
    <dbReference type="eggNOG" id="ENOG5030USN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1757710_0_0_11"/>
    <dbReference type="OMA" id="LVLMSEW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="148" mass="15309" checksum="8E203D18E773C487" modified="2010-04-20" version="1">MLPVGPKHYDRPVTDDEVAGPSPLEYVVRAAGAVVVTAAAVVFAVVEAFLVPFTLGGVYVPVAAVLAVAVNLSLPRLALWLVRLRSLALLPSLTWFVIVILGTVPTSAGDLVIHDAWPGMALLLGGAASVAISGYRIVTGPTRAAMKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWF4</accession>
    <name>D3PWF4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1608</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016882.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1608"/>
    <dbReference type="EnsemblBacteria" id="ADD41311">
        <property type="protein sequence ID" value="ADD41311"/>
        <property type="gene ID" value="Snas_1608"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1608"/>
    <dbReference type="eggNOG" id="COG0628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031275_6_0_11"/>
    <dbReference type="OMA" id="YLQFEAY"/>
    <dbReference type="OrthoDB" id="944044at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="371" mass="39016" checksum="65078F7480B0154B" modified="2010-04-20" version="1">MRKRRKKTGDKAGADEAPAGPQLGPAGSPFAKTSFHHGFYMGVGLLLAYALYLAVEVTLSLLIVILVAGFLAIGLNPLVTRIQGWGMPRGLAVATVCLGVLLIVCGGLMSIVPAIITEVTKFVEAIPGLVQHYSEQEWLKNLDKKYHLLDQAQEALKGIKPSTVLEAAGGLAGVVGGVVGSVFDGVMISLLTIYFLVSFDRLKGGFYKLLPAPRRQRAQALGDVILAKVGAYTVGALGIGATAGVCSYVFMFFAGVPYAIALAFVVAILDLIPQIGATLGAVVVTLVGLTVSVWVALACAIFFIIYQQLENWVIYPTIMRRSVKVSDLAAILGILIGAGLMGVVGALLAVPAVAAIQLIVREVYIPRQDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWI6</accession>
    <name>D3PWI6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3546"/>
    <dbReference type="EnsemblBacteria" id="ADD43208">
        <property type="protein sequence ID" value="ADD43208"/>
        <property type="gene ID" value="Snas_3546"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3546"/>
    <dbReference type="eggNOG" id="ENOG502ZC86">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087059_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039020">
        <property type="entry name" value="PaxB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42038">
        <property type="entry name" value="PTHR42038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="264" mass="29089" checksum="A446E2AC7E3F8659" modified="2010-04-20" version="1">MGNMVLMLTALSGIAWTIVYIAAIRVGFRDRTYAMPLVALGLNFAWEVIYTVHGFDTGASVQTYINLAWTLADAVIVYTFFRFGRRELPGFIGRGVFVGGGVLVFAACFAVQWLFVVEFDWTLAVRYSAFLQNLLMSGLFIAMLIARRGPRGQSMVIAVAKWIGTLAPTIVFGVYEGSTFILGIGILCSVFDLAYIGLLWMVQRRPQLLVARATEAEMDRCAAGGSLADDAHRFRSGRARTADTRHRVLIEHVDVGATQYGRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWQ5</accession>
    <name>D3PWQ5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminomethyltransferase</fullName>
            <ecNumber evidence="3">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_3617</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GcvT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3617"/>
    <dbReference type="EnsemblBacteria" id="ADD43277">
        <property type="protein sequence ID" value="ADD43277"/>
        <property type="gene ID" value="Snas_3617"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3617"/>
    <dbReference type="eggNOG" id="COG0404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_10_2_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GCS_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GCV_T" evidence="8">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T_C" evidence="9">
        <location>
            <begin position="251"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="380"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="410" mass="44372" checksum="40F70E2D3EA8CFF8" modified="2010-04-20" version="1">MPAEFAGAVTEHEAVRESVGVFDLSHKGKLVISGSDPAHVLNRCLTNDVHHLTSPGKTQYTLACDDDGGVIADGMLYRFDRDSFMMFPSGAGWLDFAKRLDAEVGDEITIGVIHDSHGILSLQGPEAAVTLRRLGLAAPQEYMFFDISQAEWGNSFICRTDFAGQPGFDIIATNPVIAAMWDELLDAGVTPCGLRARDSLRLEAGNALHGTDFNEHVTAIEARLAWAIGWNKRQFWGKEALEAQRTTGTQRRIFGLTATSPATLETGATIYDGQQQVGTITSACHSPTLNKPIALALFEPIYQAGTELQVDTTTGRVAATVTKPPFGTTPQPASLPRPRVMTAGRCLATRALRRPHHRYWPSARCSRPVPLGLRDHATASHGVRLRTYSPGGTRTNPSAQASSSRSRASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWR8</accession>
    <name>D3PWR8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3630"/>
    <dbReference type="EnsemblBacteria" id="ADD43290">
        <property type="protein sequence ID" value="ADD43290"/>
        <property type="gene ID" value="Snas_3630"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3630"/>
    <dbReference type="HOGENOM" id="CLU_1517035_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="177" mass="20063" checksum="64639507903F9442" modified="2010-04-20" version="1">MIMTAFVITNTSGIAIGLFCSVLWLWLLRRIRPRIKISSKIAEKVDPELGPSRFYIKISNLRRRAAVDLQIELVTLHLKQASNGEIYAKTMIPIQNALPFVLPGRDADCIYGHVLRLAIRHDLRAELANGEATIVQLRIYARDELSGMGRVFEKRYTDPETDLIQGAFSPGETYEIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWU5</accession>
    <name>D3PWU5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <shortName evidence="5">HMBPP reductase</shortName>
            <ecNumber evidence="5">1.17.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ispH</name>
        <name evidence="6" type="ordered locus">Snas_5538</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24488"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24825"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IspH family.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.4" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5538"/>
    <dbReference type="EnsemblBacteria" id="ADD45169">
        <property type="protein sequence ID" value="ADD45169"/>
        <property type="gene ID" value="Snas_5538"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5538"/>
    <dbReference type="eggNOG" id="COG0761">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027486_1_0_11"/>
    <dbReference type="OMA" id="HNKYVVD"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00097"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13944">
        <property type="entry name" value="lytB_ispH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00191">
        <property type="entry name" value="IspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30426">
        <property type="entry name" value="PTHR30426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00216">
        <property type="entry name" value="ispH_lytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="236"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="334" mass="36293" checksum="CD6DB3B422938DB2" modified="2010-04-20" version="1">MGCVRTMEPMSAAAKRVLLAKPRGYCAGVDRAVETVEKALELYGPPVYVRKQIVHNKHVVATLEEAGAIFVEENDEVPPGSIVVFSAHGVAPEVHEQAKQRDLKAIDATCPLVTKVHSEARRFAAQDYDILLIGHDGHEEVIGTTGEAPENITLVDGPEDVKNVKVRDENKVVWLSQTTLSVDETMDTVDGLRQRFPLLQSPPSDDICYATQNRQQVVKEIADDCDVMLVVGSTNSSNSVRLVEVALQAGSRAGYLVDYAHEIQESWLEGATTVGVTSGASVPDDLVTGVLEFLAERGFTDVAEVESVKEKLTFSLPRELVRDMKAKEAAQASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWV9</accession>
    <name>D3PWV9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5552"/>
    <dbReference type="EnsemblBacteria" id="ADD45183">
        <property type="protein sequence ID" value="ADD45183"/>
        <property type="gene ID" value="Snas_5552"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5552"/>
    <dbReference type="HOGENOM" id="CLU_3296847_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="40" mass="4326" checksum="87FE249A2019B212" modified="2010-04-20" version="1">MTTINTFGALIGIPVGVIFLLAGAVLLPLWQITEDNKRND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWY5</accession>
    <name>D3PWY5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5578</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020780.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5578"/>
    <dbReference type="EnsemblBacteria" id="ADD45209">
        <property type="protein sequence ID" value="ADD45209"/>
        <property type="gene ID" value="Snas_5578"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5578"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="PMWFFLN"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="439"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="15"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="478" mass="49287" checksum="B8416FB38F4440A8" modified="2010-04-20" version="1">MSRKASPPPSRRWTALALIALAQFMVIMDTSIIGVALPKMQKELGFSQENLSWVFNAYVVVFGGLLLLGGRLSDLFGARRLFSLGWIVLGAGSLVAGVAGDVPTELIGRGVQGVGAALIAPSALTLLMMLFGANPKELTKAFAVYGAAAPAGGTAGVFLGGLITEYASWPWVFYINIPIAILALAAAPALLPGGALAPRGSIDVVGALTVTLGLGAAVFAIVRAPEIGWGDPATWGVLLLAAVLLVGFLLSQARKRQPLMPLSIFRAANLAAANLAQLLLGAAWIPMWFFLNLYLQQVLGYSAFPSGAALLPMTVLIMVGMVALAPRLMARFGAKAMIVTGLVLLAGGLYWMSFIRPDGNFWVDVLPASLLAALGMSLAFIPSLQTAISAAKPEEGGLASGIVNTSYQIGSALGLAVVTAVAAGYGADRLGDKVALTDGFSVAFIAAALVAAVAAVLTVVTVRTRKAAETETKVDSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWZ7</accession>
    <name>D3PWZ7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5591"/>
    <dbReference type="EnsemblBacteria" id="ADD45221">
        <property type="protein sequence ID" value="ADD45221"/>
        <property type="gene ID" value="Snas_5591"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5591"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089258_4_0_11"/>
    <dbReference type="OMA" id="NRPERTT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="16"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="210" mass="24338" checksum="19E2E36F029BAF97" modified="2010-04-20" version="1">MTMTTPPRRSALALTVLVFLAWESMHAYKIQQLIKEFGKDRVVNVKQRASVYQTIDRLLRTELIRVRETSSADNRPERTIYEITDTGRDTARRWLREALASTGNEYPEFPAALAQLPLLPPSEVAEQLQVRLDAQRAEYAQMSEWFDQDPPQLHRLFLIEEEYRFAVLTAEIGWLESTIADLRSGALTWDETWLRQQAQPYSSENPDTNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXC5</accession>
    <name>D3PXC5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine dioxygenase type I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1688</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cysteine dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016959.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1688"/>
    <dbReference type="EnsemblBacteria" id="ADD41388">
        <property type="protein sequence ID" value="ADD41388"/>
        <property type="gene ID" value="Snas_1688"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1688"/>
    <dbReference type="eggNOG" id="COG5553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102185_0_1_11"/>
    <dbReference type="OMA" id="TTRWYHR"/>
    <dbReference type="OrthoDB" id="1571420at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010300">
        <property type="entry name" value="CDO_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918">
        <property type="entry name" value="PTHR12918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05995">
        <property type="entry name" value="CDO_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="153" mass="17107" checksum="4B7B37D3297B7C9B" modified="2010-04-20" version="1">MTSNSRGDFLDIARSWAEDPSAWTARPRFDPQQRWYHRMHVGDGYEVWLLTWLPGQETELHDHGGSAGAFTVVSGELTEFTPSATSAGLSTWTLRSGQGHRFGARFIHKVTNRGTEPAISVHAYGPALTIMRRYELTESGLRMANVEMAGAQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXF5</accession>
    <name>D3PXF5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016989.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1719"/>
    <dbReference type="EnsemblBacteria" id="ADD41418">
        <property type="protein sequence ID" value="ADD41418"/>
        <property type="gene ID" value="Snas_1719"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1719"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_1_0_11"/>
    <dbReference type="OMA" id="WQTDRIL"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="6"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="402" mass="43869" checksum="482C46FC0AE2735A" modified="2010-04-20" version="1">MTTPRTVLISGAGIGGPALAYWLARYGFAPTVVEIARELRTGGQPVDFRGETHRTVLTRMGIWDDLQATDTGGSPFSFVDETGRQLAALPGEFAGGEVEIRRGDLSRLLYERTRSSTEYLFGDSITRLTQRADGVAVEFASGTRRRFDLVIGADGVHSNVRRLTMGPESKFVKQFDYYVAFWSLRNDFDAPPITTMYNVPGKVIGVAADAADPARAYATVFFASPPLEYDRHDPRQQKDIVARQFTGVGWHAPRLLAGLREATDLYFDGIVKVTTPQWSKGRTALLGDAAYGATIGGMGAGTSMVGAYTLAGELATSGGDHQAAFATYQERLAKYVRKCQRGGEGAGRFFAPRGKYGPWLRNRMFNSAAFMKWMLKIADSQAENVELPDYPALLRGSAATTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXR5</accession>
    <name>D3PXR5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">von Willebrand factor type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3738"/>
    <dbReference type="EnsemblBacteria" id="ADD43395">
        <property type="protein sequence ID" value="ADD43395"/>
        <property type="gene ID" value="Snas_3738"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3738"/>
    <dbReference type="eggNOG" id="COG1840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018489_2_0_11"/>
    <dbReference type="OMA" id="RVFTIAY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="409"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="609" mass="65756" checksum="08866D47CFE6B5CC" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY64</accession>
    <name>D3PY64_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5763"/>
    <dbReference type="EnsemblBacteria" id="ADD45393">
        <property type="protein sequence ID" value="ADD45393"/>
        <property type="gene ID" value="Snas_5763"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5763"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045789_0_0_11"/>
    <dbReference type="OMA" id="RIYIADE"/>
    <dbReference type="OrthoDB" id="1514411at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="475" mass="52346" checksum="6870009BC315B8BF" modified="2010-04-20" version="1">MPQAPTPGFPPPGLPGQYPPGFPPPRATTSKRSIGLVALILAAVLLSGVSMILGFTLGGQGGKLAEGAIPAPAEGEAPSEAFIKEKSEVLLDESAEGLLDGDEDTWLSAYDSSIHDQMKKQYTSLKALQVSNFDYQIIGDPNGRDSEWTVKVGLNYCFGAKKGGKCAPTGMIFDTQWRWQDQELLATQVSESSTKPDESSQFSIGARPWEVEELKAEAGDRAVVAATDNASDDYDVKETLEIAEAAAENADKYAVYGKVDKYVIFLGDDADIAKWYGLGSGLPQQAIGFALPLPQIDKEGKPVPGGSEVVLFAERLKQIEKDFGKEGKEEFEATVRHELGHVATLHHSPPHTPKDQNADWWLSEGIAELIDHDPKEKIDDYPREKQAKEFLKSSSWDGELIAPEGNDPYGSAKYGVAFYWTYYLYDEYGKDKFMDFFERVARKGDDPEEAAKESFDKSYEDILKECKKYVKKEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY90</accession>
    <name>D3PY90_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1759"/>
    <dbReference type="EnsemblBacteria" id="ADD41457">
        <property type="protein sequence ID" value="ADD41457"/>
        <property type="gene ID" value="Snas_1759"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1759"/>
    <dbReference type="HOGENOM" id="CLU_3276980_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="41" mass="4552" checksum="6041E936FC9D8443" modified="2010-04-20" version="1">MDYTDEVEDYEPEDTLEGSTEDELLAEDEDVLADDEGEPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYI6</accession>
    <name>D3PYI6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Protein translocase subunit SecA</fullName>
            <ecNumber evidence="14">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">secA</name>
        <name evidence="20" type="ordered locus">Snas_1857</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
            <orientation evidence="14">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="14">Distribution is 50-50.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14 15">Belongs to the SecA family.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="14"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017124.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1857"/>
    <dbReference type="EnsemblBacteria" id="ADD41553">
        <property type="protein sequence ID" value="ADD41553"/>
        <property type="gene ID" value="Snas_1857"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1857"/>
    <dbReference type="eggNOG" id="COG0653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005314_3_0_11"/>
    <dbReference type="OMA" id="MVHYDVQ"/>
    <dbReference type="OrthoDB" id="212453at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020937">
        <property type="entry name" value="SecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011116">
        <property type="entry name" value="SecA_Wing/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036266">
        <property type="entry name" value="SecA_Wing/Scaffold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07516">
        <property type="entry name" value="SecA_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="SSF81767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81886">
        <property type="entry name" value="SSF81886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00963">
        <property type="entry name" value="secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01312">
        <property type="entry name" value="SECA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 14 15" id="KW-0653">Protein transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14" id="KW-1278">Translocase</keyword>
    <keyword evidence="12 14 15" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 14 15" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SECA_MOTOR_DEAD" evidence="19">
        <location>
            <begin position="1"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="87"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="419"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="832"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="835"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="914"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="103"/>
            <end position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ADD41553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="955" mass="106881" checksum="29BF5286D167C177" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYS6</accession>
    <name>D3PYS6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3853</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019080.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3853"/>
    <dbReference type="EnsemblBacteria" id="ADD43509">
        <property type="protein sequence ID" value="ADD43509"/>
        <property type="gene ID" value="Snas_3853"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3853"/>
    <dbReference type="HOGENOM" id="CLU_969465_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="287" mass="30822" checksum="6864DA2E36D01B9F" modified="2010-04-20" version="1">MNDQLRRAFSTALGDTEPPSTITPSELAGTGRRKQRNRRIALAGSGTALTLAAVTGIALVLSPATGGLGDDSATDMPGGDSGESPGESSVEGLPDDSFKYATHFAQINFEKVYDEVEYKADGGDEPLQLEPYGEDDPSSPAVGRAVFPDSENENMQVVLYPPGDWSSKAGDINPENPESSRYPVNCWSGETQGSEVTTSCDKKDLGDDGLLRTAVIKEEWANSGIVITYRTALFRTDGTAVVVDTKCSTTNDDERSQCDRDNLLTADADKTEKFVTSLPPIPKEWRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYV1</accession>
    <name>D3PYV1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019105.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3879"/>
    <dbReference type="EnsemblBacteria" id="ADD43534">
        <property type="protein sequence ID" value="ADD43534"/>
        <property type="gene ID" value="Snas_3879"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3879"/>
    <dbReference type="eggNOG" id="ENOG5033A8E">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_167343_2_0_11"/>
    <dbReference type="OMA" id="IAFRKIT"/>
    <dbReference type="OrthoDB" id="2087009at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046165">
        <property type="entry name" value="DUF6167"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19664">
        <property type="entry name" value="DUF6167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005670567" evidence="1">
        <location>
            <begin position="26"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="87" mass="9109" checksum="E732C08604191A8B" modified="2010-04-20" version="1">MVKRLLWLAAGVAVGVIVVRKLARGADALSPAGIGERLRNTAVTAGSGVRSFMSDVGEGMHEKEAELHEAIAAGEPVGELLEDDDDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYV9</accession>
    <name>D3PYV9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PfkB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3887"/>
    <dbReference type="EnsemblBacteria" id="ADD43542">
        <property type="protein sequence ID" value="ADD43542"/>
        <property type="gene ID" value="Snas_3887"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3887"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_6_0_11"/>
    <dbReference type="OMA" id="MAMFYAN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="26"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="314" mass="33391" checksum="DAC610993EBE660D" modified="2010-04-20" version="1">MNTPRTDFDLIGIGESMALVAPDPPAPLRERPKLRMGVAGAESNVVTYFSLLGAKAAWAGRVGDDPFGELVCRQLAAVGADTSFIEVDPALPTGVYFKDPDKMNTRVYYYRKGSAATGMGRKLVDSLPRAKIVHLTGITAALSDSCLDLMVHALIERPWPGALMSFDVNYRPKLWPVETASSVIRTLASASDLVFVGLDEAETLWGITRPEDVRYHLTGPKTLVVKNGEIGATIFEGTADGIFMESPIVKVVEPVGAGDAFAAGYLFAVLKGAVPRARLRMGHLIAGGALRVSGDIGPLPGQAWITAALNDGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYY0</accession>
    <name>D3PYY0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5779</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020980.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5779"/>
    <dbReference type="EnsemblBacteria" id="ADD45409">
        <property type="protein sequence ID" value="ADD45409"/>
        <property type="gene ID" value="Snas_5779"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5779"/>
    <dbReference type="eggNOG" id="ENOG5032U2Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065134_0_0_11"/>
    <dbReference type="OMA" id="SGEPYLE"/>
    <dbReference type="OrthoDB" id="1577717at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048101" evidence="2">
        <location>
            <begin position="29"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="351" mass="36600" checksum="E60B25D8E38B7550" modified="2010-04-20" version="1">MTRTPASWRFIALAGVLFALLWPGTAAAHGEEGLNDTDYRVTVTEQPRLPGVEVREVEAGARLELRNTGDRSVEILGYEREPYAEIRPEGVFVNVNSPASYLNETTDPDARVPAAASPALAPEWDKVSDEPVIRWHDHRAGWMNAQPPPVVTADPSRPHKVLDWDIPLRSGTQLYTVSGTVEWVPPPAAATWWAAALLLAGGLFVATFKPADLRPVAGLVGVLGLAAIADAVGRAVTSAELETGWLAALVVNQSWQLLAGVAGVGAAVYALRRGSAADLALGIAAAALALLSGLSHVSCLSAAITPTPWGGDLTRVLTVAALGAGTGVAVGVLARMRQPGRTTDTAGASTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ68</accession>
    <name>D3PZ68_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type II secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5868</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021068.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5868"/>
    <dbReference type="EnsemblBacteria" id="ADD45497">
        <property type="protein sequence ID" value="ADD45497"/>
        <property type="gene ID" value="Snas_5868"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5868"/>
    <dbReference type="eggNOG" id="COG4965">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064089_0_1_11"/>
    <dbReference type="OMA" id="IWIAIAT"/>
    <dbReference type="OrthoDB" id="2079512at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="83"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="220" mass="23782" checksum="CE40C4742BE72755" modified="2010-04-20" version="1">MKPRTRLRALTRPANPSAVPTRDRRIWIAIATGILTALTIGNHYGLLVGAVTTIVVHLALRRMEPAATRRARERDRADLPFALDVFAACLHSGAPLDRALSTCAEAVNPALANRFRRAARSLTLGATLAEALTEFDSLADGHRLVQTIGRSADTGARLADSLHLLAKELRFDREQAALSHAHRAGVWMVLPLCLCFLPAFIAAGLLPVVISSLDGILNTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZC9</accession>
    <name>D3PZC9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1801 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1907"/>
    <dbReference type="EnsemblBacteria" id="ADD41603">
        <property type="protein sequence ID" value="ADD41603"/>
        <property type="gene ID" value="Snas_1907"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1907"/>
    <dbReference type="eggNOG" id="ENOG5032UDA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1309481_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014922">
        <property type="entry name" value="DUF1801"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08818">
        <property type="entry name" value="DUF1801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1801" evidence="1">
        <location>
            <begin position="118"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="210" mass="22491" checksum="2AC2C8CB86856829" modified="2010-04-20" version="1">MAICDTCGNDYWLSFEVRTITGETHTFDSFECAIHKLAPTCEHCGCKIAGHGVEASGRFFCCGHCARSSDADTGSQIRDAVGTRPGLADTVVDMDDDAVERVLAAKPEMADLGRAAYALLLELYPDAVVTVDGGDIGFGSTSGYKGLMFTLSPHREHVTIGIANGAVLPDPDGLLQGKGKLHRHVKLRSRSDLDDPRLRLLLSAALMGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZK3</accession>
    <name>D3PZK3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017248.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1981"/>
    <dbReference type="EnsemblBacteria" id="ADD41677">
        <property type="protein sequence ID" value="ADD41677"/>
        <property type="gene ID" value="Snas_1981"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1981"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_11"/>
    <dbReference type="OMA" id="AVAMICT"/>
    <dbReference type="OrthoDB" id="831053at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="328" mass="34141" checksum="40D344E23374D699" modified="2010-04-20" version="1">MKAVRLYEFGPAENLRYETVPDPEPGPGQVRIRVAAAGVHLIDTVLRAGTYDGAVMKPPQLPTIPGREVAGTVEALGEGVDTSWLGAPVVTHLGMAPGGYAELAVRDVDAVHRLAPDTGFDKAVAMIGTGRTMLGVMEMAKVTDEDVVLVTGASGGIGTLIVQYARSLGATVVGAAGGPDKTARVRDNGADVAVDYTEEDWTEKVREALGDKEITVALLGGRGGSVARDSFGLLADGGRVVTYGGGLDEADQPSKEELAKRSISVDSPLGPFMMKRPGGIRSLEEKSLAALAEGRLDPATQTFPLEQAAQAHAALENHDTIGKVVLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZK5</accession>
    <name>D3PZK5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1983</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017250.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1983"/>
    <dbReference type="EnsemblBacteria" id="ADD41679">
        <property type="protein sequence ID" value="ADD41679"/>
        <property type="gene ID" value="Snas_1983"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1983"/>
    <dbReference type="HOGENOM" id="CLU_737522_0_0_11"/>
    <dbReference type="OrthoDB" id="1576962at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="365" mass="39848" checksum="E71BF78C3E4DEAA0" modified="2010-04-20" version="1">MTEIRLDDEPDEAADGGERSPGSPRSRWITAYAVALAVLAVAVVSFVEVVGGDPDDVVTDYLGALRDGDTTEALELATVKPKQGDPRDSFLRADALRANWRITSVETRVQSSKRAIVDASIAGPDGRRDGLFRLELSRAGKWRITNPFVPLYLARPPVRSGDDREAVSLSLNGVTVTMRDHEPASGVTETSGIQLRLFPGTYAFFDGDEMVRAVDATRTWLPPGDSSSFVPYTPWLELTDTGAELAEDRVGEILSECENRTERLPDGCPFGTDAKIELDGDEHAIDGDAVTWKLDDDLELFYADSGLGYFQPVVRRPVGVALTATVDGETKSVECDFDWAMLGFRLSTEAALVFTYPYETPDTCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZT6</accession>
    <name>D3PZT6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3971"/>
    <dbReference type="EnsemblBacteria" id="ADD43623">
        <property type="protein sequence ID" value="ADD43623"/>
        <property type="gene ID" value="Snas_3971"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3971"/>
    <dbReference type="eggNOG" id="COG2816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1502581_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="53"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="179" mass="19599" checksum="7E7BAA2AB8CB57FC" modified="2010-04-20" version="1">MNGYPSLAPEAQIYQYCPKCTKPLRDYRDPVNGQLRPTCVGCGWVYYPCNPLAAIAVVETDEGIVMTHPAGGMPQAPASLPGDYIEYGETPESCLARAVWEQTGFEVETVAELVRFLQLGTSFGPALMFGFRVRVVGGRLRTDGPEGPAAVYPLNEMPALIPVRQANRRVMDAYLATRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZY1</accession>
    <name>D3PZY1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase</fullName>
            <ecNumber evidence="7">6.3.2.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Meso-A2pm-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Meso-diaminopimelate-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-tripeptide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylmuramyl-tripeptide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murE</name>
        <name evidence="12" type="ordered locus">Snas_4016</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + meso-2,6-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:23676"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the MurCDEF family. MurE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.13" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019239.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4016"/>
    <dbReference type="EnsemblBacteria" id="ADD43668">
        <property type="protein sequence ID" value="ADD43668"/>
        <property type="gene ID" value="Snas_4016"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4016"/>
    <dbReference type="eggNOG" id="COG0769">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022291_4_1_11"/>
    <dbReference type="OMA" id="FIPGRML"/>
    <dbReference type="OrthoDB" id="1861122at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008765">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00208">
        <property type="entry name" value="MurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005761">
        <property type="entry name" value="UDP-N-AcMur-Glu-dNH2Pim_ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01085">
        <property type="entry name" value="murE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 7 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7 8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="9">
        <location>
            <begin position="34"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="11">
        <location>
            <begin position="123"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="10">
        <location>
            <begin position="339"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-MurNAc-L-Ala-D-Glu binding" evidence="7">
        <location>
            <begin position="167"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Meso-diaminopimelate binding" evidence="7">
        <location>
            <begin position="414"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Meso-diaminopimelate recognition motif" evidence="7">
        <location>
            <begin position="414"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="125"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="7">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD43668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="495" mass="51512" checksum="5614F6ECDCCD535B" modified="2010-04-20" version="1">MLGFPRPETVTPIPLAALARLLSVPVDAEPGRVEVTGVSLASARVRPGDLYVAVPGARRHGAEFLAEAVERGAVAVLSDSWGVEAAVEHGLPALHHPDPRAAAGVVSSAVYGEPTKRLSVIGITGTSGKTSTAYLVEAGLKAAGRVTGLIGTVETRIGAETIVSERTTPEATELQALFAYALEQGVTDIVMEVSSHALTLHRAEGISFAVGGFTMFGLDHLDFHPTVDEYFAAKAKLFDGRCRVEVVNADDAWAKRLVTPDTVTYSLVDANATWSVDSITGSGFDQSFEVTSPHGRHHGSVRLPGRHNIANALLAYGCLTAVGVPVETAIAGVADCAGVPGRMELVSEDNPVHGVVDYAHKPDAITAVLEALRPITSGSLIAVIGAGGDRDPSKRTLMGDAAARAADLVIVTDDNPRTEDPAAVRAGVLAGVGDRPHLEVADRATAIDEAVARAKPGDTIALLGKGHESGQELADRVLPFDDRRVLADALSAARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0C3</accession>
    <name>D3Q0C3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0065</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015358.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0065"/>
    <dbReference type="EnsemblBacteria" id="ADD39787">
        <property type="protein sequence ID" value="ADD39787"/>
        <property type="gene ID" value="Snas_0065"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0065"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="YQEAGPA"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="794"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD39787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="934" mass="102822" checksum="A7EB4F0745C7D327" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0H9</accession>
    <name>D3Q0H9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2020"/>
    <dbReference type="EnsemblBacteria" id="ADD41715">
        <property type="protein sequence ID" value="ADD41715"/>
        <property type="gene ID" value="Snas_2020"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2020"/>
    <dbReference type="HOGENOM" id="CLU_121293_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="18748" checksum="312B85E122AE22FA" modified="2010-04-20" version="1">MGVVGDQLDAVEVQAISPDGEITVKLGTGDAVDVQFKSDEYFKSVPHETLSHQLGRALTLLAVGRIRKRHQILEAEGFEVYGEDDAHWDKRVRVFREKRAQVKAAGRSPKRHIAIATVGLRDFKVRFERDVTRRLSRSEFSGEFGGAVAAVISEYSAQMTQLKTAMFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0P6</accession>
    <name>D3Q0P6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2088</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017353.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2088"/>
    <dbReference type="EnsemblBacteria" id="ADD41782">
        <property type="protein sequence ID" value="ADD41782"/>
        <property type="gene ID" value="Snas_2088"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2088"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1894909_0_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="66"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="135" mass="14805" checksum="71B9DF1E6722689D" modified="2010-04-20" version="1">MSTIATPDLRNPVIAWEVIARSAVHIVREARASRRLEPLTIDGRMLLTAVTALGIDLDVPKTVSVPASLRRGLSQRETQVLLGIAGGKSNAEIGRELFITEDTVKTHARRMYRKLGARDRAHAVAEAFRTGILRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Q4</accession>
    <name>D3Q0Q4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_2096</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017361.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2096"/>
    <dbReference type="EnsemblBacteria" id="ADD41790">
        <property type="protein sequence ID" value="ADD41790"/>
        <property type="gene ID" value="Snas_2096"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2096"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_563428_0_0_11"/>
    <dbReference type="OMA" id="IMVMLVR"/>
    <dbReference type="OrthoDB" id="1207548at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="19"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="329"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="57"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="108"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD41790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="464" mass="47790" checksum="B4AEC7F74B01274A" modified="2010-04-20" version="1">MSVAIRGVKNALRNKIRTAAVCLVLAVAIGLTLSMLIANRAVDAKLTALRDDMDTTITANPAFEPKPGQQDDKSSEEDSAEDESTLLTEEQLEAVRDLDHVDSVSATLTGMLETPTDESEESGGKGPITRMGGPGGVTGETDLESPIDADDVGAPEGAKFPVPLNGVTNNVDADGKPFTLTDGEQLSDGDTRGALVSDKVAEKNGLDVGDTFTAFDEEFTVVGIAKTGEYDSIGVTMLAATVQELSEEDGYSGFTIEVDDAENLEAVTEAIGEELGSTVEVRSSSDSAMQAVSGLESVKQISWIGFLVSLMCAAVIVFFTLTMTVRERRKEVGVLKAIGGTNRGVIGQFVTEAVTLVVLGTVLGLGVAAASSNVISDVLVSSNTPSEAESDKLTNGGPGIVKAGPGGPESSQSAADLIGDVAAGIGWDTLGLGLLVALGIAILGSAVPAYLIARVRPAEVLRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Q5</accession>
    <name>D3Q0Q5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2097</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017362.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2097"/>
    <dbReference type="EnsemblBacteria" id="ADD41791">
        <property type="protein sequence ID" value="ADD41791"/>
        <property type="gene ID" value="Snas_2097"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2097"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="WKEYGDQ"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="231" mass="24781" checksum="02D2619E3ED5FF0E" modified="2010-04-20" version="1">MLQVNDVTKHFKSSGGTVAAVDGVSFDIPNGRFASIVGSSGSGKSTLLSLLGALDAPSDGSIRVGDVEITKLSARKQVAYRRSRIGFVFQQYYLVPNLTALENVMLPLEFAGLRAKARRHRAAELLKQVGITGSKPGRRPGKLSGGEQQRVSIARALANSPELILADEPTGNLDSRNGRRIVRLLKELSRSEGTTVVVVTHDRSVAADTDMTLSMQDGRIVDGDPDPDEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q145</accession>
    <name>D3Q145_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4144</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4144"/>
    <dbReference type="EnsemblBacteria" id="ADD43795">
        <property type="protein sequence ID" value="ADD43795"/>
        <property type="gene ID" value="Snas_4144"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4144"/>
    <dbReference type="eggNOG" id="COG4166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_0_3_11"/>
    <dbReference type="OMA" id="KESGDYM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049437" evidence="1">
        <location>
            <begin position="21"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="76"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="527" mass="58029" checksum="51DBD22BBA00F12E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1B4</accession>
    <name>D3Q1B4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="3">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_6070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021265.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6070"/>
    <dbReference type="EnsemblBacteria" id="ADD45694">
        <property type="protein sequence ID" value="ADD45694"/>
        <property type="gene ID" value="Snas_6070"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6070"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_10_0_11"/>
    <dbReference type="OMA" id="TMEFESF"/>
    <dbReference type="OrthoDB" id="1626282at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="4"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="6">
        <location>
            <begin position="170"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="79"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="129"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="469" mass="48966" checksum="EAE70838C757BAB5" modified="2010-04-20" version="1">MPKYEQFNLPDLAEGLVDAEIIKWLVSPGDTVTLNQPIVEVETAKALTEIPSPYAGQISKLHGDEGTTVDVGQPLVTFDLDPDGSAPAEVAEEEEDTKVLVGYGPKKVSTKRRARKPSGSAPAAAQPAPVAEPARPVPAQAPAPQPPKAEPPAPAPAPALTATPQRIAVLAKPPVRKLAKDLGVDLTTITGTGPSGSITRDDVQSATTQAAAQASPSVKAHQGLNAAPVGGEERIPIKGVRKLTAQNMSHSAFTAPHVTEFLQLDVTATMEAVARLKTLPNFDGVKVSPLLLVAKAMLLAAKRHPMINSSWDEAAQEIVVKHYVNLGIAAATPRGLIVPNVKNAESLSLRELAEALNALTATAREGKTPPADMSGGTMTITNVGVFGVDTGTPILPPGESAILAFGAVRDLPWVHEGQVVPRKVTTLSLSFDHRIVDGELGSKFLADVGAFLADPGTRLLAWSLGSRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1F5</accession>
    <name>D3Q1F5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021306.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6111"/>
    <dbReference type="EnsemblBacteria" id="ADD45735">
        <property type="protein sequence ID" value="ADD45735"/>
        <property type="gene ID" value="Snas_6111"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6111"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043786_0_0_11"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="337" mass="38304" checksum="2A79001B827DC2E0" modified="2010-04-20" version="1">MDITRLLPEDTPMMDAFWELYTDVFEHDQPGSPPAQRKSAEVDIANLRSDMRQEYHLAHVNQQLAGYVRLLFPLLDNKHFMYVNGCVRPEHRRRGVGSELLELALRRGRSCGRVTIGAHTSEPLPGGPYRSTSGRDFLRAKGFDLAHSMRDFSVDLENIKEKIEEDLVDEFLPHAWEYELLSWSGPTPEEHLPAVTALANRFVSEVPLGDLALEDKNIDVERQRAAESLDAVRGRTNVSAYARHPASGELVAHSVISVDDESPEFAHQQVTLVHPEHRGHRLGTLVKIESHRLLRREFPGVRTLFTSVAEVNTHMLAINERLGFVEVDRQLDFQRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1T7</accession>
    <name>D3Q1T7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GntR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0216</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015506.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0216"/>
    <dbReference type="EnsemblBacteria" id="ADD39935">
        <property type="protein sequence ID" value="ADD39935"/>
        <property type="gene ID" value="Snas_0216"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0216"/>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_5_11"/>
    <dbReference type="OMA" id="TWQEHRK"/>
    <dbReference type="OrthoDB" id="1875458at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD39935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="235" mass="26196" checksum="AD955AEC719FD38B" modified="2010-04-20" version="1">MPDALRPMSRRRLYEQVLDRLRDYGTEAGLKAGDRLPPERELAQRLGVSRASVKQAIVVLEVQGLVEVRHGGGTYLLTDRLDTEPVDSLVERRGRLPDVLDAREALETRLAALAAERRTDADLTAIEQALEFMAAEIDNGEYGVEGDRRFHASVTAAAHSPLLAQFMKSIAEKITESRNESLRQPGRPRKSLAQHHRILDAIAEQAPGKAAEAMRRHVRTVAKVRLLDWDPDSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2K3</accession>
    <name>D3Q2K3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4287"/>
    <dbReference type="EnsemblBacteria" id="ADD43936">
        <property type="protein sequence ID" value="ADD43936"/>
        <property type="gene ID" value="Snas_4287"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4287"/>
    <dbReference type="eggNOG" id="COG2890">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1110521_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="46"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="259" mass="29044" checksum="9E9DE90553873658" modified="2010-04-20" version="1">MAMEWVEGFYSTTGKWWADAESDVSDRDRDRAASLSRWLGPERGRVLELGSGYGNTAAAIAQAGHEVIGVEISDRIDAASRHAAPDSPRFVQADFYGVELPGRFDAVCYFNGFGIGTDADQRRLLRRIASEWLTGNGVALIDVFNPFVWASWDGDEELLRARPEAGYRHELRQLNRFDPVNGRAVDTWWRTDEPQRGFTQDLRCYTPADLRLLLEGTGLRLSAVVVGDEELDLAKPHVSHQPLLTDRHEYLAVLRPDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2N9</accession>
    <name>D3Q2N9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021361.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6167"/>
    <dbReference type="EnsemblBacteria" id="ADD45790">
        <property type="protein sequence ID" value="ADD45790"/>
        <property type="gene ID" value="Snas_6167"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6167"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_0_11"/>
    <dbReference type="OMA" id="RWNGRIN"/>
    <dbReference type="OrthoDB" id="816674at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="402" mass="43658" checksum="0C4C264E100CD516" modified="2010-04-20" version="1">MSVDSKPSPYTETTGSARHAAFAELAKTGPVQRITLFTGVTVWHVTGYAEIREVMSNPDVVKTADQVPHRDHVPEAVSAAMNSHMLSANPPHHTRLRRLVSAAFTRRRIETLEPRITQIAESLADDLATQSADGSAVDVISGFGYPLPITVIAELIGVPVPDRDDFRRWSSIVVYGPIHTPEVYLDATTSLIDYVRRLIDDKRANPADDLLTDLVNVRDGGDRLSDDELTSTVALLLVAGHETTVNLIANTMYALLSHPGQLTALRADPERIPAAIEESLRFDGPVQIGIPSFTAAPVRVGDVTIPAGEVIVTALLAANRDPGRFPNPDTFDVSRPPTPHLTFGHGIHHCLGAPLARLEGRIAIRTLLDRFGDIRLADPDTEPSRHPGLLLNGLTDLTVHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q355</accession>
    <name>D3Q355_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015596.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0307"/>
    <dbReference type="EnsemblBacteria" id="ADD40025">
        <property type="protein sequence ID" value="ADD40025"/>
        <property type="gene ID" value="Snas_0307"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0307"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046685_0_0_11"/>
    <dbReference type="OMA" id="EFWQLYV"/>
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    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:transmembrane transporter activity"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="414" mass="42997" checksum="688E86F0FD52233A" modified="2010-04-20" version="1">MSVITRGTSVGRIGLLWCAYEFLNDFILLYALETLLFVDTGLSTGEITSLLIAWSLTSVLLEVPSGVLADVLPRRLLLTIAPLLRSVGYGLWVAFPSYPAFLAGFVLWGVSGALQTGATEALVYDNLKHHRATDRYATYAGRARASQTVAVLIAMLLTPTVYALGGYAALGIGSVAVCALAAVVALAMPEHREERHAEFDGLRAYGRTLLAGLREVRGSRVVMFSVAMVAIVPAIWGSLEEFAALLAVEFGAGKPLVPYLVAALTGGITVGALLAGRAERLSWRRLAAGLGLGAAVTVTAGLYGGIAGFLLLLPAFAMFNAAGVVAEVRLQNAITGPARATVTSVAGLSLEASSIVIYAAYALAASQVGHGGAFALSGVGYGLVALAIIVVVSVSARRPPRRQVKAFDQPGLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3A6</accession>
    <name>D3Q3A6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017518.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2258"/>
    <dbReference type="EnsemblBacteria" id="ADD41947">
        <property type="protein sequence ID" value="ADD41947"/>
        <property type="gene ID" value="Snas_2258"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2258"/>
    <dbReference type="eggNOG" id="ENOG5032EMY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_653657_0_0_11"/>
    <dbReference type="OrthoDB" id="2061074at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
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        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
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        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
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        <location>
            <begin position="329"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="420" mass="45170" checksum="75ED35C6C4E4F89C" modified="2010-04-20" version="1">MTWKRIAGWSFAAAPPLVLVGWALMRLNGAGGQEPGWTLAHIAWGLNAVMHAVICVELYRRAKDTTGKGRVLATGCLIVGVLGAVCLLAQMVIDLVVGFATDNRTDMRAMSGQIHDLYGVQLAVYDVGPVLLFLVLITQAIHVAVLKRGTTAFAALVTLAVVVSGTELLLEIPLRLAQASSALILWIAFVPVARELSRRDTSDVTRATRWRSLAGWSLILAPVGQVGGWTLMMLGGNDGDRLLSTVAHTVWLIGFLMLGVVCVELYRRVRGHGAGQLFARVSLAVALISIAASVLEMLVDLYTLFATVNRAQMEALDEQIRGIPGAEQILYGFGTQAVYIGFLALVIQLAVLKRISATTLTFVLATLVLFVGYELLDNVVEGPVRQSIMPLAVLCMWLALAPLGWRLLKPVTTTAGPRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4A7</accession>
    <name>D3Q4A7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Daunorubicin resistance ABC transporter ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_6376</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021563.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6376"/>
    <dbReference type="EnsemblBacteria" id="ADD45992">
        <property type="protein sequence ID" value="ADD45992"/>
        <property type="gene ID" value="Snas_6376"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6376"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="ICGFDVQ"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043215">
        <property type="term" value="P:daunorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900753">
        <property type="term" value="P:doxorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005894">
        <property type="entry name" value="DrrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01188">
        <property type="entry name" value="drrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="313" mass="33587" checksum="38C4F88E036D4A1C" modified="2010-04-20" version="1">MTNTAIAVSGLRKAYKDKVVLDGIDLDVRAGTIFSLLGPNGAGKTTTVNVLSTLTKADGGSVRVAGHDVETDAKAVRSAIGVTGQFAAVDELLTGQENLQLMVDLNRAATGNGKHAVARLLERFDLVEAAKKPASTYSGGMRRKLDLAMTLVGNPRIIFLDEPTTGLDPRSRRTMWSIIRDLVADGVTIFLTTQYLDEADQLADRIAVLDKGHLVAQGTSAELKRQIPGTHVRLQFAAPAELEAATRLFPGSTPDADSLTLRVPSDTGTKSLWTLLNRLNENSLSAEEFTVHTPDLDDVFLALTGHTTEVESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4B8</accession>
    <name>D3Q4B8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015649.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0360"/>
    <dbReference type="EnsemblBacteria" id="ADD40078">
        <property type="protein sequence ID" value="ADD40078"/>
        <property type="gene ID" value="Snas_0360"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0360"/>
    <dbReference type="eggNOG" id="ENOG502ZD0Q">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1843898_0_0_11"/>
    <dbReference type="OrthoDB" id="2035728at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045428">
        <property type="entry name" value="EACC1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19953">
        <property type="entry name" value="EACC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="139" mass="15353" checksum="43BBCDAFFE903D5A" modified="2010-04-20" version="1">MTTTLAIVTDDPEQARQLLAWLRRESELRGVTDLRLLPPRQTGGHLGEATDTVLAILSNPGAITAVATTIGVWLGQRVGRTRIRVKDGEREVEIETTSRRRAEEYTRTILAELNAGPADSVSLTVRGDNHEHDRTETTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4H2</accession>
    <name>D3Q4H2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0415"/>
    <dbReference type="EnsemblBacteria" id="ADD40132">
        <property type="protein sequence ID" value="ADD40132"/>
        <property type="gene ID" value="Snas_0415"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0415"/>
    <dbReference type="HOGENOM" id="CLU_3376197_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="34" mass="3474" checksum="A65AF845787F8E4D" modified="2010-04-20" version="1">MGKLLALVIGGVCLLVVVAVIVGIVLLVSKAKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4R4</accession>
    <name>D3Q4R4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42094">
        <property type="protein sequence ID" value="ADD42094"/>
        <property type="gene ID" value="Snas_2411"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2411"/>
    <dbReference type="HOGENOM" id="CLU_2398169_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="93" mass="9934" checksum="77D288970550E346" modified="2010-04-20" version="1">MIRAQLWPRVSATVAVPKTAAQSKNITAETAARGDRCSSAAMALSSRVTTLSRHSSPTWTHRMTMATVTFLGLASPGLRFMGVPFPTSTFVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4U3</accession>
    <name>D3Q4U3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RarD protein, DMT superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_2440</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EamA transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017694.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2440"/>
    <dbReference type="EnsemblBacteria" id="ADD42123">
        <property type="protein sequence ID" value="ADD42123"/>
        <property type="gene ID" value="Snas_2440"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2440"/>
    <dbReference type="eggNOG" id="COG2962">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054508_1_0_11"/>
    <dbReference type="OMA" id="HRMVWSL"/>
    <dbReference type="OrthoDB" id="1391352at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004626">
        <property type="entry name" value="RarD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF114">
        <property type="entry name" value="PTHR22911:SF114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00688">
        <property type="entry name" value="rarD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="9">
        <location>
            <begin position="45"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD42123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="311" mass="32634" checksum="7BDE7584E1E56E4A" modified="2010-04-20" version="1">MSTRTDSRTTPAAPGDGIVSHAAGMAAGSGAYVLFGLLALYWPLLEPAGALEILAHRIVWSLLFVVALLAVTSGRKAFKTLRGNRKALYYLVAAGCLVGANWGFYIWAVNNNHVVEAALGYYINPLFSTLLGTLLLRERLHRAQWAAIAIAGSGVLWLAIAAGSPPWIALALAGTFGCYGLAKKQANLPAMESLAVETATLVLPAAAFLVFLSAQGTGHFGADTGHSLLLASSGLATAVPLLLFGFAATRIPLTAVGMLQFLTPTIQFLIGVFGMHETVGEAGLGPYVLVWIAVAMYVVCDVRIRRRAAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4X2</accession>
    <name>D3Q4X2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2469</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017723.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2469"/>
    <dbReference type="EnsemblBacteria" id="ADD42152">
        <property type="protein sequence ID" value="ADD42152"/>
        <property type="gene ID" value="Snas_2469"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2469"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="VAMDVRM"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="143"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="214" mass="23000" checksum="5286D21DFB5410F0" modified="2010-04-20" version="1">MNLRVLLADDEALIRAGLAAIIDAEADLEVVAEAADGVDAVALTKRHRPDVVLMDVRMPNVDGIEATRQILRIPELSPKIIVVTTFDNDDYVYEALRAGANGFLLKRTPPDDLLAGIRVVARGDALLFPAAVRRLAAGHTGRSTLDAAGLTEREAEVLRLMARGLSNAEIAARLFLSAETVKTHVAKILAKLRVRDRTQAVIKAYEAGFVSASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Y4</accession>
    <name>D3Q4Y4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2481</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017735.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2481"/>
    <dbReference type="EnsemblBacteria" id="ADD42164">
        <property type="protein sequence ID" value="ADD42164"/>
        <property type="gene ID" value="Snas_2481"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2481"/>
    <dbReference type="HOGENOM" id="CLU_1019069_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="273" mass="29179" checksum="AFC8D243A19F00CC" modified="2010-04-20" version="1">MNDDAHGLLDRALPDGQVPFNVDPAQIVRRGRRLRRRRAFAAAGGIATAAVLGLVVTVAGLSPGSVADHGPAASKSSGEQTDSWADESPWELTKRDPFTNADTATATGGVVDALEQIAEVDVHDADGLKGFHLGRYTETSPNGDLDRDLLHGKGQFSSENYDLTTDFEVSIYEPGLVDAVEDFVDCEAERVKCSESTGPADEKIISRTVDTVSGSLTIRTYEVYVYRADRSIAKLATRPDIDPGVESNGVVTTPLSTTQVRDVALAIPPKLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q577</accession>
    <name>D3Q577_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_4481</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019697.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4481"/>
    <dbReference type="EnsemblBacteria" id="ADD44126">
        <property type="protein sequence ID" value="ADD44126"/>
        <property type="gene ID" value="Snas_4481"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4481"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012341_1_0_11"/>
    <dbReference type="OMA" id="PQSFHWT"/>
    <dbReference type="OrthoDB" id="856767at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="724"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="781"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="820"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="17"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="299"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="495"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="757"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD44126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="854" mass="90686" checksum="B01A73B2DCCC3355" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5N0</accession>
    <name>D3Q5N0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein serine/threonine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021661.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6475"/>
    <dbReference type="EnsemblBacteria" id="ADD46090">
        <property type="protein sequence ID" value="ADD46090"/>
        <property type="gene ID" value="Snas_6475"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6475"/>
    <dbReference type="eggNOG" id="COG0631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025431_0_0_11"/>
    <dbReference type="OMA" id="ITQDHTW"/>
    <dbReference type="OrthoDB" id="1835483at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017018">
        <property type="term" value="F:myosin phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD46090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="463" mass="48983" checksum="92ACFF8B4D951A61" modified="2010-04-20" version="1">MTLTLRYAAISDRGLIRSGNQDSVYAGPRLIAVADGMGGMAAGDLASNIVIGVLAALDEDVPRGELTAALADSVEEANSRLRETVEEHPHMEGMGTTLTAFLFSGSSLGMVHIGDSRAYRLRQGRLTQVTKDDTYVQMLVDEGQLSADEAETHPQRSLLLRALGSNEVEPTFATLEAVAGDRYLLCSDGLSGVVSDDTIEETLRTIADPHEATDRLVQLALRGGGPDNVTVLVADLVEGGVEESEPIVAGAAAADRGASSADPSTAAARASAATTAPEPEPPAEELYEPAPSAAQTKQMKRHRRRRVKWYVLATVLLLGIVFSGGYLVIQGQYYVGVNDEKHVAVFRGINTELFGVPMSSEEYDSDVSVKDLTPDARDRVESGIQASSRDRAISIMEGITTGESNLLEPCPSPSPSPSETSKSPDKSKSPSPSESDKESSPSETPSQGPSSSLEPGVDCRPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5S0</accession>
    <name>D3Q5S0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0504</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015790.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0504"/>
    <dbReference type="EnsemblBacteria" id="ADD40219">
        <property type="protein sequence ID" value="ADD40219"/>
        <property type="gene ID" value="Snas_0504"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0504"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_8_11"/>
    <dbReference type="OMA" id="AANVDCR"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="3">
        <location>
            <begin position="202"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="407" mass="43480" checksum="6DEFBE587DEA0522" modified="2010-04-20" version="1">MPDSPPHTGQRRLTWLRRYTWWFLIPYPLTAATVGTIQAIRHDHPGGVLALILIAFAVATVVSVRWFDAVTRHEARDWPTLADWVLFAVAAAGLAGTAWLISPFPYRPLGWLLLASALTAAVILRLPARHRLAALVVMTGLIAAATALLARAGLAAPLTVLGVAALVASFAAIIWVQWWSFDVARQLEQARSVAAELAVTRERLRFAADLHDIQGHHLQVIALKSELAARLGGRDPDKAVALMREVQDLARDALSDTRAVVAGYRSVSPGTEITNATKVLTAAGIEATANLPGTDPGRGFAGERELGLLIREATTNILRHARPTRAEFDLTATGEGLSVRIRNDGADSGATSGDGTGLAGLRDRFEAVGGSLDWRSEAGRFTVSARLPRAAAPPDPGRSPDTEGSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5W9</accession>
    <name>D3Q5W9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LamG domain protein jellyroll fold domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0554</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015839.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0554"/>
    <dbReference type="EnsemblBacteria" id="ADD40268">
        <property type="protein sequence ID" value="ADD40268"/>
        <property type="gene ID" value="Snas_0554"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0554"/>
    <dbReference type="eggNOG" id="COG3534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_478086_0_0_11"/>
    <dbReference type="OMA" id="APGAFQI"/>
    <dbReference type="OrthoDB" id="1832114at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049569" evidence="3">
        <location>
            <begin position="37"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="199"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="419"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="570" mass="59643" checksum="6D70E7E18E91176B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5Y0</accession>
    <name>D3Q5Y0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YCII-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015850.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0565"/>
    <dbReference type="EnsemblBacteria" id="ADD40279">
        <property type="protein sequence ID" value="ADD40279"/>
        <property type="gene ID" value="Snas_0565"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0565"/>
    <dbReference type="eggNOG" id="COG2350">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110355_7_2_11"/>
    <dbReference type="OMA" id="MYIVELS"/>
    <dbReference type="OrthoDB" id="1780176at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="12"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="86" mass="9508" checksum="0958C648AD18CEFE" modified="2010-04-20" version="1">MYIVELSFDGSPERLELRPAHREKLAALHAKGTCPMAGPFPDQSGAALIFDVDSEAEVDAILDDDPYYRAKGVTVVRKQPWNPLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q622</accession>
    <name>D3Q622_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017768.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2515"/>
    <dbReference type="EnsemblBacteria" id="ADD42197">
        <property type="protein sequence ID" value="ADD42197"/>
        <property type="gene ID" value="Snas_2515"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2515"/>
    <dbReference type="HOGENOM" id="CLU_1093766_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="254" mass="27506" checksum="BE2F20D57EB21DF3" modified="2010-04-20" version="1">MGETYAEGIAASEDLKAFKAAYQADIQDADDMVREWIRPLAANAPLISEVIEWYVGIDMWALYDRSRILRYLGEEPSPYDEILRSDAFAAAEDAWTGKGGEAFFAYCRGGGNSDKSFDRYLDAVRQAAQKHHTAISPPSGNDGLLGALRDALKDFLTVLNGSIKGFKAKRESNLEIPTSFTDPPQFIIDSISNVYKANVKDAEQIGGAGDAIAGQVEALADQYVVALDTSQLKDVPTGALHDGPGPLDGAWKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q632</accession>
    <name>D3Q632_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017778.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2526"/>
    <dbReference type="EnsemblBacteria" id="ADD42207">
        <property type="protein sequence ID" value="ADD42207"/>
        <property type="gene ID" value="Snas_2526"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2526"/>
    <dbReference type="eggNOG" id="COG0412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054590_7_2_11"/>
    <dbReference type="OMA" id="FCFGGSH"/>
    <dbReference type="OrthoDB" id="1889569at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DLH" evidence="1">
        <location>
            <begin position="35"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="248" mass="27112" checksum="115B5E806C43897E" modified="2010-04-20" version="1">MCHDTDSAPPKLSESGSVASEELLELTSADGTSFTVFHTEPGQPLGRSLVVFPDRRGVHQYYLELARRFAEAGFSVAVLDYYGRTAGPGPRGDDFDWAPNFRQLVPDNVSADAAAVVEFLRRRHPDDDVYSVGFCLGGGHSWRLSSVVAGLNGCVGFYGLPSLAAERVTEISAPLLLLLAGDDVATTAEQFDDFRRQLDEAGKPYEHKVYEGAPHSFFDGGNPEWSEISADAWRRVLDFTDRYASTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6F5</accession>
    <name>D3Q6F5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019769.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4554"/>
    <dbReference type="EnsemblBacteria" id="ADD44198">
        <property type="protein sequence ID" value="ADD44198"/>
        <property type="gene ID" value="Snas_4554"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4554"/>
    <dbReference type="eggNOG" id="ENOG50335I8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_623904_0_0_11"/>
    <dbReference type="OMA" id="LWSAPCD"/>
    <dbReference type="OrthoDB" id="1702201at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="291"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="391" mass="41446" checksum="C2EB9979D00A0FE3" modified="2010-04-20" version="1">MTGQRLEQRAASMLAAYQRIAAKMYTLDSHAGRRFLKDEQLSGATADIAGRVNARAAVLWSRFDELRRLSDQIPTDVDGLGDTARAKLEALLGSECVKLDASGVPALASGDAVTTESSLSAFADDIEAECAELLRLCSEVDDACGVVADAIAEVTGSLEDVTARAETLGMAGNATLAELRADRSSLLETTLSDPASAVDDLAGLAELSRRIGEFGQRLASLEAVARDFPARLSALRADLAELGEAEDRTAQTCALAVEKILDPAPPRFTPQAATLSNALRELGETAADSDRHSLAARLSELTSRVEEAIRQCRRVADTAEALLDRRAELRGRLAAYSRKAARLGVIEEPRVAASAATARELLSLAPCDLRSATSAVRQFQQEISGAQEAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6L8</accession>
    <name>D3Q6L8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019832.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4618"/>
    <dbReference type="EnsemblBacteria" id="ADD44261">
        <property type="protein sequence ID" value="ADD44261"/>
        <property type="gene ID" value="Snas_4618"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4618"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_10_4_11"/>
    <dbReference type="OMA" id="YRDKVGF"/>
    <dbReference type="OrthoDB" id="1900922at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="134" mass="14685" checksum="0F271AAC604B086A" modified="2010-04-20" version="1">MDWKIEVVPVPVTDIERAKSFYADKLGFNVDIDFTLPDDTRIIQLTPHNSGCSIALGAPTSMPPGSLHGVQIVVDDIATARQTLLTNGVDITPVQHFDGKTYVDGPGDDWNSWAFFADPDGNKWTLQERPATTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6P3</accession>
    <name>D3Q6P3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Trehalose-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4643</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4643"/>
    <dbReference type="CAZy" id="GH15">
        <property type="family name" value="Glycoside Hydrolase Family 15"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44286">
        <property type="protein sequence ID" value="ADD44286"/>
        <property type="gene ID" value="Snas_4643"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4643"/>
    <dbReference type="eggNOG" id="COG1877">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3387">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010399_3_0_11"/>
    <dbReference type="OMA" id="GGFHLCA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045582">
        <property type="entry name" value="Trehalase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19291">
        <property type="entry name" value="DUF5911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5911" evidence="2">
        <location>
            <begin position="267"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_15" evidence="1">
        <location>
            <begin position="497"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="867" mass="93652" checksum="403B6091B9E578F4" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Q3</accession>
    <name>D3Q6Q3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC-type sugar transport system periplasmic component-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4653</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019867.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4653"/>
    <dbReference type="EnsemblBacteria" id="ADD44296">
        <property type="protein sequence ID" value="ADD44296"/>
        <property type="gene ID" value="Snas_4653"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4653"/>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_3_9_11"/>
    <dbReference type="OMA" id="TEPCAYR"/>
    <dbReference type="OrthoDB" id="1378040at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048698" evidence="2">
        <location>
            <begin position="30"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="3">
        <location>
            <begin position="92"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="397" mass="43918" checksum="6C2F00EB74C54648" modified="2010-04-20" version="1">MRLLRTAVAGLAITAMLLTGCTTDKPSDEAEGKDDKSSEGDWFVKEDYERQLKQRDAEPEGDADKPYLQAIDPDWVETTEYKKKGGDATICFSNASVSNPWRVTGWLTMQEQVKQLKKSGEIKEFRVSDAEDKDNKQISDIEAFVDSGDCDSIIISPSTTATLTPAVKTACKSGVPVVVFDRGVETDCAVSFIHPIGGYAYGADGAEFLVDKLKPGSKVLALRILPGVDVLENRWAAAKQIFKDSEIEVVGDEFTKGDGAKIKDIVTQYLERGDVDGIWMDAGDGAVAALEAFEDADKDYPVMVGEDEIGFLRKWKETKITAIAPVYSNFQWRTPVLAAVKILNGEKVPKEWVLPQEPITEDNLDEYLKRNKDMPNLHYAKFGGEDLPGFPDAWKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6W5</accession>
    <name>D3Q6W5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Inosine/uridine-preferring nucleoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0651</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015935.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0651"/>
    <dbReference type="EnsemblBacteria" id="ADD40364">
        <property type="protein sequence ID" value="ADD40364"/>
        <property type="gene ID" value="Snas_0651"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0651"/>
    <dbReference type="eggNOG" id="COG1957">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036838_2_2_11"/>
    <dbReference type="OMA" id="REKAHEW"/>
    <dbReference type="OrthoDB" id="1763387at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="PTHR12304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="SSF53590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IU_nuc_hydro" evidence="3">
        <location>
            <begin position="5"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="321" mass="33043" checksum="9D00D109C3341BF3" modified="2010-04-20" version="1">MAIDVVLDVDTGVDDALALLFATAHPALRVRAVTCVAGNVDVDQATRNSLAVLDAAGHPDIPVARGADRPLLRPFNGARAVHGDNGLGGIDVPDAKRSADSVHAVELLRRTIMDSPGEVTLIALAPLTNVALLLRMYPETAAALGNVMVMGGSVGAGNTTAAAEFNIWQDPEAAAIVLSSGVPLTMYGLDVFYQVTVDAAGVKRLLESSKPGASLAARLLEGRTGTWRHESRITEPEAACVGDAGAVCAVADPQGLTTRSLPVHVALGEGPTRGLTLVDVRGNPNSVPLSGDVGVGQVDVGVAVDGARYRRLFVETVAADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7B4</accession>
    <name>D3Q7B4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uridine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2709</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2709"/>
    <dbReference type="EnsemblBacteria" id="ADD42385">
        <property type="protein sequence ID" value="ADD42385"/>
        <property type="gene ID" value="Snas_2709"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2709"/>
    <dbReference type="eggNOG" id="COG0572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090613_0_0_11"/>
    <dbReference type="OMA" id="NRYHAAC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="225" mass="25705" checksum="F817049B3D966DBC" modified="2010-04-20" version="1">MDGQVARDELIEALARLIARRRRDGVLRVAVDGPDAAGKTTLADELAPRIPAPATVIRAGIDSFHRPRAERLRRGGLSPEGCYHDTFDYDALRRQLLEPLGPNGDRRYRTAVFDHREDRPLDEPLRLAPPGSVLICDGVFLLRPQLRHHWDLRVLLDIDEDEIERRALERDASMMGGADVVRERYRRRYLPAQRLYRAEAAPERFADVLIDNNQPATPRVLAWPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7D5</accession>
    <name>D3Q7D5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-NAD/AcoX kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017977.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2730"/>
    <dbReference type="EnsemblBacteria" id="ADD42406">
        <property type="protein sequence ID" value="ADD42406"/>
        <property type="gene ID" value="Snas_2730"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2730"/>
    <dbReference type="eggNOG" id="COG3199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064691_0_0_11"/>
    <dbReference type="OMA" id="RGNQQFS"/>
    <dbReference type="OrthoDB" id="869726at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039065">
        <property type="entry name" value="AcoX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40697">
        <property type="entry name" value="PTHR40697"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="446" mass="43745" checksum="FA03E99D228767A9" modified="2010-04-20" version="1">MTTVGLLVNPVAGLGGTVGLKGTDGPLAERARDLGATPRATDRAALALSELAARWPGFALTAEPEPAAATVGGHQPAPAAKPDGGAGAADADTLPDPATRFDGPTLLTVAGDMGADAALLAGVAATVVCDRPSATSAADTVRAAQALVRAGAELLLFAGGDGTARDVLAALESGQPTTDDGSGSGSGSGSGSGSGSGSGHSVAPTARDGVAVIGIPAGVKIHSAVYAVNPRAAGEVAAAFLAGTAASAPAEVLDRPDGETVGTVLYGHLPVPRLPHRVQSGKIGSTVTGGDDPAGIAAHLRDTRSLGGIDIVGPGTTTNAVLAALGVTVEPTGVTVVDAAGLVATDADATTLVRLAAARPARVVVSPIGGQGFLLGRGNQQLTPELLRSCGRDAIMIISGEAKLAALAGRPLLVDTGDETLDADLRGYRPVITGRDTTVMYRIGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7E2</accession>
    <name>D3Q7E2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 37</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017984.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2737"/>
    <dbReference type="CAZy" id="GH63">
        <property type="family name" value="Glycoside Hydrolase Family 63"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42413">
        <property type="protein sequence ID" value="ADD42413"/>
        <property type="gene ID" value="Snas_2737"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2737"/>
    <dbReference type="eggNOG" id="COG3408">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015270_0_1_11"/>
    <dbReference type="OMA" id="WLEEMYP"/>
    <dbReference type="OrthoDB" id="70058at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005991">
        <property type="term" value="P:trehalose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="PTHR23403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048293" evidence="1">
        <location>
            <begin position="26"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="708" mass="79109" checksum="8BF0EB2F88E6A058" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7E9</accession>
    <name>D3Q7E9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cobyric acid synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cobQ</name>
        <name evidence="7" type="ordered locus">Snas_2744</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CobB/CobQ family. CobQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2744"/>
    <dbReference type="EnsemblBacteria" id="ADD42420">
        <property type="protein sequence ID" value="ADD42420"/>
        <property type="gene ID" value="Snas_2744"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2744"/>
    <dbReference type="eggNOG" id="COG1492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019250_2_2_11"/>
    <dbReference type="OMA" id="EIHHGVA"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01750">
        <property type="entry name" value="GATase1_CobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00028">
        <property type="entry name" value="CobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033949">
        <property type="entry name" value="CobQ_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004459">
        <property type="entry name" value="CobQ_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21343:SF1">
        <property type="entry name" value="PTHR21343:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00313">
        <property type="entry name" value="cobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="3 4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="5">
        <location>
            <begin position="10"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="GATase_3" evidence="6">
        <location>
            <begin position="264"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="512" mass="53991" checksum="B72704B777127D3A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7L6</accession>
    <name>D3Q7L6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4715</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019929.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4715"/>
    <dbReference type="EnsemblBacteria" id="ADD44358">
        <property type="protein sequence ID" value="ADD44358"/>
        <property type="gene ID" value="Snas_4715"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4715"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_60_2_11"/>
    <dbReference type="OMA" id="NHFQVTT"/>
    <dbReference type="OrthoDB" id="1452500at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="12"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="413" mass="42711" checksum="6CA97B91227C0991" modified="2010-04-20" version="1">MTVSKFRELDATVRLLCLNQFGINAGFFMLMPFLAAYLSGGIGLVAGLVGLLLGVRNFSQQGLFFAGGALADRFGYKPMILAGCALRTVGFGVLGFTDSLPGLVLGMVATGAAGALFNPAVRAYIAAQAGDKRVEAFAVFNVFYQAGILAGPLIGLALSGVDFSVTCFTAAAIFAALTLAQARLLPKRHGENSDRPSMVDSWRTVARNRGFLLFSVVMAATYVLNFQTYLALPLLLNQHTTPAAASLTTTVVFAIAGILTITAQVRVTAWCKNRWGPSGSLCLGVIVMGAAFLPVAAVLAWRPDAGVVIAAVVVCGTILATGTMITYPFEMDTIVTLAREQHVASHYGVFQTVAGIAVAAGNLAVGAGLDATGVGPWSTLPWAGLALAGFGCALGLRAIAIRGATSVAQPVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7N3</accession>
    <name>D3Q7N3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_4733</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019946.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4733"/>
    <dbReference type="EnsemblBacteria" id="ADD44375">
        <property type="protein sequence ID" value="ADD44375"/>
        <property type="gene ID" value="Snas_4733"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4733"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="QTCIEVK"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="11"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="7">
        <location>
            <begin position="367"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="276"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="342"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="481"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="344"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="503" mass="53082" checksum="363ED639BE9A1C2D" modified="2010-04-20" version="1">METGQVLKERYRLTGRIAVGGMGEVWRAEDEMLHRTVAIKILHPALAADPQFQHRFIQEARTLASLNAPGLIDLYDACEETSPDGSPLSYLVMELVDAKPLSTMLAESGRVEPGKLLPILAQCATALGAAHGAGIVHRDIKPANILVAEDGTVTLIDFGIARRPGDSKLTAAGSVIGTVEYASPEQLRGVKLTGASDIYSLGVVGYECLTGAPPFYGDTAAVIAAHLNREPAPLPDDVPRAVADVITTAMAKDPQQRFGSAAELASACRGAASGTRVMPMGRAQPPVPPTEPIDIEPSSEAPESVDRMLRKRTLTTVLITLGVVLVIVLAVGVAWFAGRNSGGETADDKSSSKSSSSASPSPTGPDAPANSTLANASNDQCVAMDYGLFSDAVVLADCGGDTTKFEFAPDSGNKGVFEIVNTADGDKACVNWRYGDEDVLAGECTPDTAWKFEWIETKAGVDVWRIHSVTNSKFCLAAASGAPQGQDCNDDENQRWETKEAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7P4</accession>
    <name>D3Q7P4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M48 Ste24p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_4744</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019957.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4744"/>
    <dbReference type="EnsemblBacteria" id="ADD44386">
        <property type="protein sequence ID" value="ADD44386"/>
        <property type="gene ID" value="Snas_4744"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4744"/>
    <dbReference type="eggNOG" id="COG0501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056335_0_0_11"/>
    <dbReference type="OMA" id="CHNISIF"/>
    <dbReference type="OrthoDB" id="1707650at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="132"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="314" mass="32245" checksum="06629D90DA63B062" modified="2010-04-20" version="1">MSGAALLGYAAVLSLCGASWLRDAGWTSRAPRLAIFTWFSLVASVLLALVAAGVLLIVPATGFHHGILDFIGACLATLEEQYGLVGGALLGGLSFVLAVGLPVLFAGSGAAEAISASMTRRRHLRGLSASARPDRRTGALVLDHDTAAAYCLPGRGGVVVVTTGAMRAVDGGGLAAVLHHERAHLAGRHHVLTALAHALHRPLCFLPLFAELPEQIGHLVELRADDVAAAKSGRRVLAESLLAFAEASVTPALALPAAGADTVDRMRRLITAPQRLNRPGAVGIAATGTVAMALPIVVTVLSLATVTYMACCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7V4</accession>
    <name>D3Q7V4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016030.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0747"/>
    <dbReference type="EnsemblBacteria" id="ADD40459">
        <property type="protein sequence ID" value="ADD40459"/>
        <property type="gene ID" value="Snas_0747"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0747"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027938_4_4_11"/>
    <dbReference type="OMA" id="RKRRMRF"/>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="38"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="237" mass="26023" checksum="52374D8D0672820B" modified="2010-04-20" version="1">MPELVYPPVVGTAKAVLRLMDWHMDAVGAEHLPRAGGAVVACNHVSYLDYIFLGLTVTRHTGRYVRFMAKREIFDNAIGGPFMRSMNHISVDRSHGGGAYAEAEAALGRGEIIGVFPEATISQSFTVKKLKSGAARLAVARQVPLVPMAVWGGQRLWTKGHPRDFRRHVPISVTIGEPLRPSATDNPDDVTAELRERMSTLSQNVQRNYPERPIGETDNWWQPAYLGGSAPESEPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q803</accession>
    <name>D3Q803_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0796</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0796"/>
    <dbReference type="EnsemblBacteria" id="ADD40508">
        <property type="protein sequence ID" value="ADD40508"/>
        <property type="gene ID" value="Snas_0796"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0796"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="997"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1014"/>
            <end position="1033"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1033" mass="112441" checksum="2FCD90D821D263B7" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q860</accession>
    <name>D3Q860_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0854</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016136.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0854"/>
    <dbReference type="EnsemblBacteria" id="ADD40565">
        <property type="protein sequence ID" value="ADD40565"/>
        <property type="gene ID" value="Snas_0854"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0854"/>
    <dbReference type="HOGENOM" id="CLU_2156809_0_0_11"/>
    <dbReference type="OrthoDB" id="1946681at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="111" mass="12011" checksum="2FF56FC2E01EBE4A" modified="2010-04-20" version="1">MGETVLKEANHRAEADGMTAWDPRRLVTVTVGPGGILRDVTIEPDAYSYLTPKQLSTTVTTTYQTAVTALREATVAQFMDLCGVKVKPEEVANGKTRLHNLLDKLAGQPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8D3</accession>
    <name>D3Q8D3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018078.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2831"/>
    <dbReference type="EnsemblBacteria" id="ADD42507">
        <property type="protein sequence ID" value="ADD42507"/>
        <property type="gene ID" value="Snas_2831"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2831"/>
    <dbReference type="eggNOG" id="COG1652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027946_0_0_11"/>
    <dbReference type="OMA" id="HQRWATG"/>
    <dbReference type="OrthoDB" id="324626at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048749" evidence="1">
        <location>
            <begin position="33"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="535" mass="57034" checksum="7B24476F8A861043" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8K4</accession>
    <name>D3Q8K4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020017.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4805"/>
    <dbReference type="EnsemblBacteria" id="ADD44446">
        <property type="protein sequence ID" value="ADD44446"/>
        <property type="gene ID" value="Snas_4805"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4805"/>
    <dbReference type="eggNOG" id="COG0718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2182347_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="109" mass="11696" checksum="6B950CCE1BD086F7" modified="2010-04-20" version="1">METHSDPAEPRSRQDAKLSKARVAASSPKGVVTVVYNGHGDGLSLELKPGAKQRYESETMAGFVTAALRAADRAVDALRQHAVDDRDDDTRPSRAAANMDVARCFGRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8N9</accession>
    <name>D3Q8N9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4840"/>
    <dbReference type="EnsemblBacteria" id="ADD44481">
        <property type="protein sequence ID" value="ADD44481"/>
        <property type="gene ID" value="Snas_4840"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4840"/>
    <dbReference type="eggNOG" id="COG2834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057675_0_0_11"/>
    <dbReference type="OMA" id="DGPDRQK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd16325">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004564">
        <property type="entry name" value="OM_lipoprot_carrier_LolA-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048755" evidence="1">
        <location>
            <begin position="35"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="367" mass="38976" checksum="E360AA9A6B5C38D7" modified="2010-04-20" version="1">MSRKSARRRFAVPIALAAGIVTAAAGTGIVSASGASDLPDRSAAQLLEDVQNSDIEGLSGTVVQNANLGLPSLGQSGGGLTQLADGSNQMRVWYAAPDKMRTAVLSDYGESDTIRNGEDVWTWNSEGGEATHYTLPKKAADAPLWPPSEMGGADPAKAAEQALKAIEPTTKVSTSQPVEVAGRDAYELVLEPKDGESLVDRVTLAIDAEHGVPLRTQVYSDDEKEAAFDIGFSRVDFGTPDKENFTFTAPKGVTVTEGTDELSDFLSNGKKPAADADVKAVGKGWTTVLTGEFDLKELSKETKKKAKHGGESVDLEKVLKQLPEVSGKWGSGRLFESKLVNALLTDDGRFYIGSVTPERLYEVADGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q940</accession>
    <name>D3Q940_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-quinone oxidoreductase subunit K</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NADH dehydrogenase I subunit K</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nuoK</name>
        <name evidence="6" type="ordered locus">Snas_0938</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the complex I subunit 4L family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016220.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0938"/>
    <dbReference type="EnsemblBacteria" id="ADD40649">
        <property type="protein sequence ID" value="ADD40649"/>
        <property type="gene ID" value="Snas_0938"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0938"/>
    <dbReference type="eggNOG" id="COG0713">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144724_1_0_11"/>
    <dbReference type="OMA" id="FDVWLSR"/>
    <dbReference type="OrthoDB" id="2081663at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01456">
        <property type="entry name" value="NDH1_NuoK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001133">
        <property type="entry name" value="NADH_UbQ_OxRdtase_chain4L/K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039428">
        <property type="entry name" value="NUOK/Mnh_C1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11434">
        <property type="entry name" value="PTHR11434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00420">
        <property type="entry name" value="Oxidored_q2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="110" mass="11515" checksum="AACE357012CF10F3" modified="2010-04-20" version="1">MHPVIPYVLAALLFGVGVYGVLVRRNAVLVLAAVELMLGAVNLVLVTADVAPLTGEGGGYTGQSFALFVIVIAAAEIGVGLALVLHLFRLRGSIDTERIDAEDDEREVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q952</accession>
    <name>D3Q952_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GH26 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0950</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 26 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016232.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0950"/>
    <dbReference type="EnsemblBacteria" id="ADD40661">
        <property type="protein sequence ID" value="ADD40661"/>
        <property type="gene ID" value="Snas_0950"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0950"/>
    <dbReference type="eggNOG" id="COG4124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038234_2_0_11"/>
    <dbReference type="OMA" id="HHEPEDD"/>
    <dbReference type="OrthoDB" id="669354at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022790">
        <property type="entry name" value="GH26_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51764">
        <property type="entry name" value="GH26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH26" evidence="4">
        <location>
            <begin position="215"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="530" mass="56886" checksum="78B3D5C59FAA9EF8" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9G6</accession>
    <name>D3Q9G6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein 70</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2974</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018219.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2974"/>
    <dbReference type="EnsemblBacteria" id="ADD42648">
        <property type="protein sequence ID" value="ADD42648"/>
        <property type="gene ID" value="Snas_2974"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2974"/>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005965_12_0_11"/>
    <dbReference type="OMA" id="PKRYIDH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="356"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="367"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="397"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="473" mass="51518" checksum="3FC3564C7A7A88A2" modified="2010-04-20" version="1">MRVLGIDFGTSNTVAILRMNDGRVKPLLFDGSPMLPSAIFLASDGRMLVGRDAERNARMDPARFEPNPKRRIDDTTIFLGDQEIPVSRAMAYVLEHVTAEARRQLGGPPEVVRMTHPARWGERRRNLLLEAAKFAGLPKPQLIPEPVGAASYFTSVLGTAVPVGRALAIYDFGGGTFDATVVRRTQTGFEVLSEEGLPDVGGLDFDHGIVEHLGKTYGVSHAQAWARLMNPTDDKDRRYRRTLYEDARDAKQTLSRASSADIHLPTMEVDAHLTREEFDGIARPLIERTIECMQRAIAGAKQQPKDLVGIFLVGGSSRIPMAASLIHTGLGVAPRTFEQPETVVVEGALAIGGAAAGNRPVSGPAAPGRPISGPPQRPPMQQQQRPPMQQQQRPPMQQPMAPRPQMPPAPRPIQQPMAPRPQMPPAPRPMPMQQQQPRAPRKKASQEPAVVVTIVIAAILVVGFIILLIAALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9N3</accession>
    <name>D3Q9N3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020150.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4938"/>
    <dbReference type="EnsemblBacteria" id="ADD44579">
        <property type="protein sequence ID" value="ADD44579"/>
        <property type="gene ID" value="Snas_4938"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4938"/>
    <dbReference type="eggNOG" id="ENOG5031SWQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1531627_0_0_11"/>
    <dbReference type="OMA" id="EDHYVPP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="175" mass="18845" checksum="95DE01D548ABC891" modified="2010-04-20" version="1">MTRHSDDDPDRDRAGGAEEPGEGADRLDPSEVDERFAELIADLKDDTPGWPEDEPKSDEPARRAHPSSGDDDEPSLLELWDTELEDDDDDEEEDTYRPPPPPPLPVPSLPAILGVLLIIGGLVLIVQPSLLDVGEGLGRTTGIAAFGGGVLMLIWRLRPEPEDGEDDDPGNGAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9N4</accession>
    <name>D3Q9N4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4939</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020151.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4939"/>
    <dbReference type="EnsemblBacteria" id="ADD44580">
        <property type="protein sequence ID" value="ADD44580"/>
        <property type="gene ID" value="Snas_4939"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4939"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_39_0_11"/>
    <dbReference type="OrthoDB" id="961781at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="363"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="42"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="493" mass="52964" checksum="1806ACBAF37C4EFC" modified="2010-04-20" version="1">MQVATVMPQRVQTWWDGFLAKRGRPLTTGDITVVKPPELKRATAAASVGNCMEWYDFGVFSYLTATIGAVFYPSGNPVAQLLASFATFSVAFLVRPLGGLFFGPLGDRIGRTKVLAATMVLMAVGTFAIGFIPSYASIGIAAPILLLLARMLQGFSTGGEYGGASTFTAEYAPDRRRGYFCSFLDFGTFIGYAIGSGVVTLMTLALSETAMLSWGWRIPFLVAGPLGLIGLYIRLKLEDTPAYQQQEEAVEAAEPPVAHPIRTTVRDHWRPLLVCMGLVLLYNVTNYMVTAYLPTYLTQELGQRAHIADMFILAAMVLVVVTITFIGRASDRYGRKVTFNIGAVGLVVLALPCFWMMRAGGVVLPLAGVLVLALLLAFFAGTSAATLPALFPTRIRYTAMAVGFNISVAAFGGTTPLVTEALVAWSGDLMVPAYYLMAAGAIGLIAIAYLPETAGLPLAGAQPQVVSSGEARELVMVTREYFTRLLPPRRKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9P0</accession>
    <name>D3Q9P0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020157.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4945"/>
    <dbReference type="EnsemblBacteria" id="ADD44586">
        <property type="protein sequence ID" value="ADD44586"/>
        <property type="gene ID" value="Snas_4945"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4945"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="MNERATA"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="155"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="351" mass="37460" checksum="2C9196C5AF8B2120" modified="2010-04-20" version="1">MRRDDIDRKGPKWWPWWLLRFPWILVPFPVAFIQLIGIRGAAMWAECGGGEHGWGPGREESPHCDWQDTSVDPVAFVLALIGPVALFAVRGFPRTVVAVCALITAVYYPLGLPPGPIYLSLIAALLAWLFKVRSERNAQAKAAQRAQAQQRAGAERLRIAQELHDVLAHHISLINVQSGVALHLVDEKPEQTRVALSAIKGASKEALTALRGALDALRSTDDAAPRSPTDGLAKLDALVDSVRNAGIEVDVTVTGQQRELDPVVDLAALRIIQESLTNVLRHSNARHVRIRIDHGDSLDITVADDGGGGVPIPGNGLTGMNERATAVGGTCTAGPAAAGGFAVHARLPGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9U1</accession>
    <name>D3Q9U1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, IclR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5000"/>
    <dbReference type="EnsemblBacteria" id="ADD44637">
        <property type="protein sequence ID" value="ADD44637"/>
        <property type="gene ID" value="Snas_5000"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5000"/>
    <dbReference type="eggNOG" id="COG1414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_4_1_11"/>
    <dbReference type="OMA" id="EPDRLHR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="8"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="67"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="232" mass="24820" checksum="7CA23EE6B7702261" modified="2010-04-20" version="1">MGNSISGVGVLDKAVLILTSCAEGASLAELVDKSGLPRATAHRLAQALEAHRMLVRDHENRWRPGPRLGELANTTPDVLLQAAEPILKLLRDQTGESAQLYRRRADERICCAAAERHSGLRDTVPVGAVLPMSAGSGAQVLLAWEPPEAVLPLLPKCRFTAQTLTEVRRRGYAQSVAEREAGVASVSAPVRDRTGRVVAAISVSGPIERLGRRPGDRLAMAVIRAGQRLSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA13</accession>
    <name>D3QA13_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ADP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
            <ecNumber evidence="14">4.2.1.136</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">ADP-dependent NAD(P)HX dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">nnrD</name>
        <name evidence="17" type="ordered locus">Snas_1015</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 15">Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="14">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 15">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 14 15">
            <text>(6S)-NADHX + ADP = AMP + H(+) + NADH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32223"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 14 15">
            <text>(6S)-NADPHX + ADP = AMP + H(+) + NADPH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32235"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="15">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 15">In the C-terminal section; belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">In the N-terminal section; belongs to the NnrE/AIBP family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.136" evidence="14"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016296.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1015"/>
    <dbReference type="EnsemblBacteria" id="ADD40725">
        <property type="protein sequence ID" value="ADD40725"/>
        <property type="gene ID" value="Snas_1015"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1015"/>
    <dbReference type="eggNOG" id="COG0062">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024853_4_0_11"/>
    <dbReference type="OMA" id="HNGGDAL"/>
    <dbReference type="OrthoDB" id="1748633at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052855">
        <property type="term" value="F:ADP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052856">
        <property type="term" value="F:NADHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052857">
        <property type="term" value="F:NADPHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017953">
        <property type="entry name" value="Carbohydrate_kinase_pred_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030677">
        <property type="entry name" value="Nnr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017184">
        <property type="entry name" value="Nnr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="SSF64153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01050">
        <property type="entry name" value="YJEF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="17" id="KW-0418">Kinase</keyword>
    <keyword evidence="12 14 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 14 15" id="KW-0520">NAD</keyword>
    <keyword evidence="9 14 15" id="KW-0521">NADP</keyword>
    <keyword evidence="7 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="16">
        <location>
            <begin position="10"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="384"/>
            <end position="388"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR017184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ADD40725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="476" mass="48746" checksum="18FF6276E401D6D3" modified="2010-04-20" version="1">MRGVWKVDQVRTAEAELMKRLPEGALMKRAAAGLAARCARLLHGIGLYGSAVTVLAGSGDNGGDALYAGALLARRGAAVTAVEIFPGRTHAAALAEFRAAGGRVTDTTPEHHDLVIDGILGIGGRPGLPDNAAIMLSRMGRVLTVAVDVPSGVDVDTGAAVAQAVRADVTVTFGCLKPALAVGAAAALAGIVDCVDIGLGPFLPEPYAKVPELSDVRSWWPHARPHDDKYTRGVLGVCAGSFRYPGAGELATAGALAGPAGYIRYAGTASRHIRYSYPEVVTKDRVADAGRVQAWTVGPGMGTDSQAASQLASAMAAPVPMCIDADALTLISDEPEALYERQSPSVITPHDREFSRLSGRTPGDDRAADALDLAQRLDCIVLLKGYRTIIANSNGDLYFNPTGDPSLATAGSGDVLAGLLGAMLAAGVPPERAAMSAAFLHGLAGREAANHGPVTASGIAKALPTAISRALGTAVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA27</accession>
    <name>D3QA27_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative periplasmic ligand-binding sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1029</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1029"/>
    <dbReference type="EnsemblBacteria" id="ADD40739">
        <property type="protein sequence ID" value="ADD40739"/>
        <property type="gene ID" value="Snas_1029"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1029"/>
    <dbReference type="HOGENOM" id="CLU_1427217_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="190" mass="19743" checksum="BB7856D88859AEA9" modified="2010-04-20" version="1">MSQPGPAQYGPPPGGMGAAPQQGGFAPQPPPSSGNATIGWVIGGIAAVLVIVAGIAGVIFFANAGNSEDSGTDGGSSSASDSSAGPSQTPTDVVNDYYDAVRAHDVDGAYKTLCSSMQGSESDFFGSYDEDEFWKTVDASTYTVGEETIKDDSNANVKVKQEVQGETYDFSADLQIESGEWKICYWNTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA94</accession>
    <name>D3QA94_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="9">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">guaA</name>
        <name evidence="12" type="ordered locus">Snas_1096</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016377.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1096"/>
    <dbReference type="MEROPS" id="C26.A07"/>
    <dbReference type="EnsemblBacteria" id="ADD40806">
        <property type="protein sequence ID" value="ADD40806"/>
        <property type="gene ID" value="Snas_1096"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1096"/>
    <dbReference type="eggNOG" id="COG0518">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0519">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014340_0_5_11"/>
    <dbReference type="OMA" id="KRKIIGH"/>
    <dbReference type="OrthoDB" id="504464at2"/>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 9 10" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="11">
        <location>
            <begin position="197"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="224"/>
            <end position="230"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD40806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="516" mass="55559" checksum="2F10239A3EC1C082" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAE5</accession>
    <name>D3QAE5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="14">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="14">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">pheT</name>
        <name evidence="19" type="ordered locus">Snas_3057</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="14"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018299.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3057"/>
    <dbReference type="EnsemblBacteria" id="ADD42728">
        <property type="protein sequence ID" value="ADD42728"/>
        <property type="gene ID" value="Snas_3057"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3057"/>
    <dbReference type="eggNOG" id="COG0072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016891_0_0_11"/>
    <dbReference type="OMA" id="ISYNWLK"/>
    <dbReference type="OrthoDB" id="53568at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02796">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00283">
        <property type="entry name" value="Phe_tRNA_synth_beta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004532">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033714">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PTHR10947"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="SSF54991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00472">
        <property type="entry name" value="pheT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 14 19" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 15" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="16">
        <location>
            <begin position="42"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="B5" evidence="18">
        <location>
            <begin position="407"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="17">
        <location>
            <begin position="732"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ADD42728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="827" mass="88436" checksum="ACDA095D49A484BC" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAI0</accession>
    <name>D3QAI0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3092"/>
    <dbReference type="EnsemblBacteria" id="ADD42763">
        <property type="protein sequence ID" value="ADD42763"/>
        <property type="gene ID" value="Snas_3092"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3092"/>
    <dbReference type="HOGENOM" id="CLU_2371414_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="95" mass="10044" checksum="197F72649182F044" modified="2010-04-20" version="1">MPLPGFRLDHTETIIRLYRGDALVTMGCELTLPAREGARMADGTTQITGNREPVNPGDATDVPAVPARAAQLADADAALSDATAAVPEQSREETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAJ1</accession>
    <name>D3QAJ1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3103</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018345.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3103"/>
    <dbReference type="EnsemblBacteria" id="ADD42774">
        <property type="protein sequence ID" value="ADD42774"/>
        <property type="gene ID" value="Snas_3103"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3103"/>
    <dbReference type="eggNOG" id="ENOG5030KYS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1314058_0_0_11"/>
    <dbReference type="OrthoDB" id="1583204at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009936">
        <property type="entry name" value="DUF1468"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07331">
        <property type="entry name" value="TctB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="21813" checksum="17D51862548D3A1E" modified="2010-04-20" version="1">MEKSASPRRRGRAPLGPRIFGGGALLVGALAFTLALSDLNEGRDAEFTPVNAAFAPLIITGLWVLFAAIYFVKQLINPYADYPEFAEEPPPARTDDAYPEPDGDDGEPKPDGEPDADQADAHPADVQWKPAALVAVALMVYVLLLDTVGFVLLTPLFFVAITWIFGSRKIIRDVIVAVVLTVGTYLLFTSVLGLTLAEGLFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAZ3</accession>
    <name>D3QAZ3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5154"/>
    <dbReference type="EnsemblBacteria" id="ADD44789">
        <property type="protein sequence ID" value="ADD44789"/>
        <property type="gene ID" value="Snas_5154"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5154"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_1_11"/>
    <dbReference type="OMA" id="IEGPCHH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="309" mass="32510" checksum="01704129F6FF8D9C" modified="2010-04-20" version="1">MSLSPRVPDLPSLELLVSVARLGSIGAAAAEHGISQPSASNRIRTMERLVGVTLLERSPRGSQLTESGQLLVEWAGAVVDAARVLDGGIDALRRRRESRLRVSASLTIAEYLLPGWLARLRTERPETSVALTVANSTEVARALIEGEADLGFVEGPYVQNGLQSVTVADDELVLVVAPGHRWARRGAPVAAPELRDTPLICREQGSGTRAAVAEALREYGTQVAPLLELASTTAVKASVAAGAGAAVTSSLSVVEELTSGRLVSVPVSGADFHRRLRAVWPRGRRPSGPAADLLRVAQAVQAARRAASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB09</accession>
    <name>D3QB09_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016397.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1116"/>
    <dbReference type="EnsemblBacteria" id="ADD40826">
        <property type="protein sequence ID" value="ADD40826"/>
        <property type="gene ID" value="Snas_1116"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1116"/>
    <dbReference type="eggNOG" id="ENOG502Z81H">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049023_0_0_11"/>
    <dbReference type="OMA" id="TRIIFHF"/>
    <dbReference type="OrthoDB" id="1297522at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="454" mass="49363" checksum="F36497197FA5A393" modified="2010-04-20" version="1">MTAENGADVEAQIAEWRAYMLRRRAIHDTDVDELEDHLRGRITDLSETGLRPDEAFLIAVKRMGSLNELSREFAREHSDRLWKQLVLAGEPEAEKGGGRRELLAMIACALLGAIAIKVPSVFGLDFDADADFYARNMSLFALPPLAAYFVWRRRAGWGVIAVLAGLFVLGAVGANAYPLAEEDQSIVLTAIHLPLALWLVVAVAYAGGDWRSDSRRMDFIRFTGEWFIYFVLIGLGGGVLAAFTAGTFAAIGLDASNFIASWLVPCGGMAAVVVAAWLVEAKQSVIENMAPVLTRVFTPLFAATIVAVLAAIVWTNSGIDVDREVLILFNLLLVVVLGLLLYSISARDPHAPAGVFDWLQLALVGSALVVDVLVLLAITGRITEFGFTPNKSAALGENVILFANLAVSAWLFLGIAKGRTPFPRLERWQTGYVAVYAVWAWIVVLVFPPVFGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB36</accession>
    <name>D3QB36_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016424.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1143"/>
    <dbReference type="EnsemblBacteria" id="ADD40853">
        <property type="protein sequence ID" value="ADD40853"/>
        <property type="gene ID" value="Snas_1143"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1143"/>
    <dbReference type="eggNOG" id="COG1835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005679_1_2_11"/>
    <dbReference type="OMA" id="ATFTHEW"/>
    <dbReference type="OrthoDB" id="1968136at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="16"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="388" mass="43350" checksum="3B9DA70F1FFDDF8B" modified="2010-04-20" version="1">MKSLSHSEYRSSSRFQALDGLRAVTVLSLVGMHFDFGALQWLIGKGKITVFFVLSGFVITLLLLRDEDKYGKVRLRNFYVRRQFRLLPAYFTVLAVAAVARFNVPDTGQNDGSWPEMAAMLPYYATFTHEWGPGTADVITFVHSWTLSYEQKFYLVWPLIFMALSIWAPRWRLPVTALIAGSCLAVIPVFGARWVQYFALILGCVLGLLLYEERTYRFIRPLTHPVAALFVAAGFLVLHVWVGTQVKFPHDPVLAWYAIGVFVLIISILNTGVVQWILMRRFFLFVGERGYSMYLVHGLAGAAVLSAAPAWGSGSIKTALIIAGVTIVFADGLYRFVELPSAAAGRRFIKWLDERKAARQRAREPIAADTPIPVEPAMAGSTGMASDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-02-10" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBD5</accession>
    <name>D3QBD5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription antitermination protein NusB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Antitermination factor NusB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nusB</name>
        <name evidence="8" type="ordered locus">Snas_3146</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the NusB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3146"/>
    <dbReference type="EnsemblBacteria" id="ADD42817">
        <property type="protein sequence ID" value="ADD42817"/>
        <property type="gene ID" value="Snas_3146"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3146"/>
    <dbReference type="eggNOG" id="COG0781">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087843_2_3_11"/>
    <dbReference type="OMA" id="DRMPVVD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00073">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011605">
        <property type="entry name" value="NusB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11078">
        <property type="entry name" value="PTHR11078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01951">
        <property type="entry name" value="nusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NusB" evidence="7">
        <location>
            <begin position="13"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="147" mass="16550" checksum="DA060873CC19B9E4" modified="2010-04-20" version="1">MSDNALAGFPARRKARKRAVDVLYEAEQRDEPIRRVLEDRRKLAVTDPQMPGIPEYTFELVDGVAEYLDEVDDVIARCLHSGWYLDRIAAVDRNILRVAAFELRYREDVDAAVAISEAVKIAEVLCGEDSPAFVNGVLQSVSELEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBH8</accession>
    <name>D3QBH8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018431.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3190"/>
    <dbReference type="EnsemblBacteria" id="ADD42860">
        <property type="protein sequence ID" value="ADD42860"/>
        <property type="gene ID" value="Snas_3190"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3190"/>
    <dbReference type="eggNOG" id="COG1247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_4_5_11"/>
    <dbReference type="OMA" id="EAAGIWT"/>
    <dbReference type="OrthoDB" id="1809950at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="163" mass="17934" checksum="A90CB70617F2DBC5" modified="2010-04-20" version="1">MHIRAMTPTDAPDVLKIYQDGIDTGNATFETTAPTWETFDHTHLPDHRLIAHDDTGPLGWIAATPTSTRHVYRGVIEHSIYIATHAQGRGVGSALLAAFVDSCETAGIWTIQAGIFPDNTPSLALHEKHGFRIIGIRHHIGQTIDGRWRDVALLERRSTTIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBJ9</accession>
    <name>D3QBJ9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase S1 and S6 chymotrypsin/Hap</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018452.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3211"/>
    <dbReference type="MEROPS" id="S01.121"/>
    <dbReference type="EnsemblBacteria" id="ADD42881">
        <property type="protein sequence ID" value="ADD42881"/>
        <property type="gene ID" value="Snas_3211"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3211"/>
    <dbReference type="eggNOG" id="COG5640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006842_7_5_11"/>
    <dbReference type="OMA" id="GWGQTCP"/>
    <dbReference type="OrthoDB" id="1468733at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049034" evidence="1">
        <location>
            <begin position="27"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="2">
        <location>
            <begin position="42"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="26445" checksum="E8CA139564125506" modified="2010-04-20" version="1">MRKRLIYSGLAVVAAAAVAVGGVGFAANADDGVDASDSQTKIIGGVDADQDYSFMASMQGSDGSHRCGASLISPEWLIIAAHCVEGEDPSGYQFRLNTKTVSDGGEVVKPTEFVVHPDYSGGVDDLALVKLEAAAESAPVKLGSEASPGTKSRILGWGATNPDGSGAPETLQQLDTAVVESSKCTEIGEKDLCTDNPNGDSGACYGDSGGPQIVDDGSGGWVLIGATSRSGNGDPTCATGPSIYTNVTAYTDWINETTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBM1</accession>
    <name>D3QBM1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018474.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3233"/>
    <dbReference type="EnsemblBacteria" id="ADD42903">
        <property type="protein sequence ID" value="ADD42903"/>
        <property type="gene ID" value="Snas_3233"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3233"/>
    <dbReference type="eggNOG" id="ENOG502Z7JX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065811_1_0_11"/>
    <dbReference type="OMA" id="FVCVVET"/>
    <dbReference type="OrthoDB" id="1666716at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="24390" checksum="54B6754F56ACFD25" modified="2010-04-20" version="1">MSDTVTSQARGTWGRVANLLWRMVKIEARGYQSMYRLVFRRPRVPSGAVGFGYHRNVLMVMIVFVVISLVELVVVDIIVRQWVFVRIPLLILGVWGVVYMFGMLCGMLTRPHAIGPKGLRVRDSTEVDLDLPWEVVHAVEQRTVTIQDKTAKVTVDDGRRTFSLRMQKETNIEVELEEPLRLRLPHGVETIDKVAFYVDDPKAFMRQMLTYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBQ5</accession>
    <name>D3QBQ5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3267</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018508.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3267"/>
    <dbReference type="EnsemblBacteria" id="ADD42937">
        <property type="protein sequence ID" value="ADD42937"/>
        <property type="gene ID" value="Snas_3267"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3267"/>
    <dbReference type="eggNOG" id="COG0662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_426937_0_0_11"/>
    <dbReference type="OMA" id="IGATHYT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="PTHR12778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin_2" evidence="7">
        <location>
            <begin position="573"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="418"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="641" mass="68012" checksum="4B9A8B149F8945D2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBV6</accession>
    <name>D3QBV6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Respiratory nitrate reductase, gamma subunit</fullName>
            <ecNumber evidence="15">1.7.99.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Snas_5210</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.7.99.4" evidence="15"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020416.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5210"/>
    <dbReference type="EnsemblBacteria" id="ADD44845">
        <property type="protein sequence ID" value="ADD44845"/>
        <property type="gene ID" value="Snas_5210"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5210"/>
    <dbReference type="eggNOG" id="COG2181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092378_0_0_11"/>
    <dbReference type="OMA" id="MVSGGFF"/>
    <dbReference type="OrthoDB" id="1873056at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009325">
        <property type="term" value="C:nitrate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008940">
        <property type="term" value="F:nitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023234">
        <property type="entry name" value="NarG-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036197">
        <property type="entry name" value="NarG-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003816">
        <property type="entry name" value="Nitrate_red_gam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02665">
        <property type="entry name" value="Nitrate_red_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103501">
        <property type="entry name" value="SSF103501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00351">
        <property type="entry name" value="narI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="9 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Nitrate_red_gam" evidence="14">
        <location>
            <begin position="6"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD44845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="244" mass="27177" checksum="25E8D8D93B69C52F" modified="2010-04-20" version="1">MTLLDHMLWGVAPYLVLLTLIGGTIWRHRYDRFGWTTRSSQLYESRLLRVASPIFHFGILLVIVGHVVGLLIPESWTRAVGVTDETYHLAALSLGALAGVATLGGIALLIWRRRTVGPVFSATTVNDKVMYLVLVAAIVAGLATTLLSTIDSIRDVPEVDYRQTVSVWFRSIWILNPDVAAMSAASMAFKIHVVIGMALFALFPFTRLVHAFSAPVGYPFRPYIVYRSRAAASRRNLRPIRRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU14</accession>
    <name>D3PU14_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016531.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1250"/>
    <dbReference type="EnsemblBacteria" id="ADD40960">
        <property type="protein sequence ID" value="ADD40960"/>
        <property type="gene ID" value="Snas_1250"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1250"/>
    <dbReference type="eggNOG" id="COG3185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1164902_0_0_11"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase_6" evidence="1">
        <location>
            <begin position="18"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Glyoxalase_6" evidence="1">
        <location>
            <begin position="130"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="243" mass="26646" checksum="35EA4567022290A7" modified="2010-04-20" version="1">MVRWLRTCLGRPSEVWRDSVDFWARVTETTAAPPDADEVLLEPDTGDAWLGLTRRATAPPTRVDLVADDAEAMVAKAYELGVTAIYDDNERFTGRSPGGLMFRVENGDRAFTEPAIVKHANGSTSSANQLCIDVGRDDWDSEVRFWENLTGWSARTTSFPEFSTLTPEDRSTCLVLLQRLDEDRPTGAHVDFSTSDVAAVREVHLAAGARGGEVFKHWTVMYDPSGAVYCLTAVDPATGESTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU15</accession>
    <name>D3PU15_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1251</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1251"/>
    <dbReference type="EnsemblBacteria" id="ADD40961">
        <property type="protein sequence ID" value="ADD40961"/>
        <property type="gene ID" value="Snas_1251"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1251"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="GRQAVCQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="20"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="291"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="428"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="568" mass="60269" checksum="8E293E0211677012" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUF1</accession>
    <name>D3PUF1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3296</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018535.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3296"/>
    <dbReference type="EnsemblBacteria" id="ADD42964">
        <property type="protein sequence ID" value="ADD42964"/>
        <property type="gene ID" value="Snas_3296"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3296"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_10_0_11"/>
    <dbReference type="OMA" id="HWFGGKE"/>
    <dbReference type="OrthoDB" id="2089619at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041678">
        <property type="entry name" value="TetR_C_16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17920">
        <property type="entry name" value="TetR_C_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="17"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="200" mass="21411" checksum="66071157842C8F56" modified="2010-04-20" version="1">MTEHTSPGRPGRWRSGAQSRQRVLDAARELFQRNGYAGTTVRAVATEAGVDPAMVFYFFGNKQGLFAAAVDMSAQLPPAIDAIFDGGLDGIGERVVRTLLENMDKSERAPLAILTRSGPGDDQTETLLRQYIDREITGRLAALLDTPDAALRAGMVNVQLLGLAVARYVVRVEPIASASVDELTTRLGAVVQHCLTGSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUH9</accession>
    <name>D3PUH9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NLP/P60 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3326</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018563.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3326"/>
    <dbReference type="EnsemblBacteria" id="ADD42992">
        <property type="protein sequence ID" value="ADD42992"/>
        <property type="gene ID" value="Snas_3326"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3326"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016043_13_2_11"/>
    <dbReference type="OMA" id="WVEPRTH"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048358" evidence="2">
        <location>
            <begin position="34"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="3">
        <location>
            <begin position="221"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="346" mass="36784" checksum="B224634C5692D2EF" modified="2010-04-20" version="1">MTGKFSRRGVLKAGAMSGLVIAGVGGAANPAAAKEPESGGAPGVGDVAYVDVAAATLWVEPDKDRKVDAPSLTNPVDLRAWLAAMSLKQRRWLIGNLETQGLYGQDVTVTAESGDWVHVVVHGQPTPRDERGYPGWVLRSQLTTQAPSGSDGPFAQVTDATTWLYDDATLSGEFMEISYGNRLPCLDQTDTALKVATPTHGDKWLCVDAATVYASEDAIPAPSGADLVADAKMFLGLPYLWAGTAGFGFDCSGLTHSLHKAHGVTIPRDSGPQKDAGTPVAAEEMRAGDLLFYGIDRVHHVGMHIGDGHMIDARTNTDKVEQRIEIVAVDEHPYAFEFAGAVRYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV16</accession>
    <name>D3PV16_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5408</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5408"/>
    <dbReference type="EnsemblBacteria" id="ADD45040">
        <property type="protein sequence ID" value="ADD45040"/>
        <property type="gene ID" value="Snas_5408"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5408"/>
    <dbReference type="HOGENOM" id="CLU_2920557_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="61" mass="6421" checksum="BBF2B2BBAF356FDF" modified="2010-04-20" version="1">MTKQSTAPTPRSSGPVTIPCRSQDCKNGFVAKEVDGQLRAEMCESCDGTGNKTVVAKECDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV29</accession>
    <name>D3PV29_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1375"/>
    <dbReference type="EnsemblBacteria" id="ADD41082">
        <property type="protein sequence ID" value="ADD41082"/>
        <property type="gene ID" value="Snas_1375"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1375"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_597043_0_0_11"/>
    <dbReference type="OMA" id="VESEPEW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005184">
        <property type="entry name" value="DUF306_Meta_HslJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038670">
        <property type="entry name" value="HslJ-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03724">
        <property type="entry name" value="META"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="458" mass="50167" checksum="30F664AA099DA27D" modified="2010-04-20" version="1">MSSVELRHLATMAAVAEEGSFGRAASRLRYTQSTVSQQIAALEKTIGGAVFERPGGPKPVRLTPLGSVVLAQGQELLAQAEALTDAVDRFKAGEGRIDIGTFQSVSIVILPRLVRRLRDRHPGCDIRLSEDEPENPRIGDLDLLFYDRPLDGDVEHLKLIDDPYLLVSRNGTFDEGPVALERLDGMPMVAWPDICDQSRMEEALASHGVRPQIVFRTAGNEALLSMVRAGMGPALLPWLALDGTDAWSDDRLRVHQLEPAPPARQIYLYWQAGRTHSPLARAAIRIAGDIATEIAERQTEPYWLSPRPIHMKSTRITLSTLGVLALAACGTGTADNGDGADKPGPEDLKGHTFAIESVEGETRGEKLMKDSKLTIKFTDDGEIKLDTDCNQRFGSVEISGDTIKTDKLAGTLMGCEETRTEQEDWASEFVESEPEWKLDGEKLILTTSDATVTMKQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV99</accession>
    <name>D3PV99_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016723.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1446"/>
    <dbReference type="EnsemblBacteria" id="ADD41152">
        <property type="protein sequence ID" value="ADD41152"/>
        <property type="gene ID" value="Snas_1446"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1446"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089258_4_1_11"/>
    <dbReference type="OMA" id="EWANVKW"/>
    <dbReference type="OrthoDB" id="1706427at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="8"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="208" mass="22623" checksum="39B787E7B91A0A41" modified="2010-04-20" version="1">MSATKLLVLGVVRIFGTAHGYLVHNELTTWGAHEWANVKWGSIYHALRQMQSKGLLESTITDDHLGRVDYTMTEAGDAEFFRLLRQALRTPESRPDSLAAGLAFLTALPRDEVISLLKERVAALEEGRAELTPLLTDEAKCNWDAEGAGHVPELFGFWAHTADTAIAWANGLISRLEAGDYVMAGESDTAFGTPGIAKPSPRAATDCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW81</accession>
    <name>D3PW81_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016809.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1534"/>
    <dbReference type="EnsemblBacteria" id="ADD41238">
        <property type="protein sequence ID" value="ADD41238"/>
        <property type="gene ID" value="Snas_1534"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1534"/>
    <dbReference type="eggNOG" id="COG1426">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_173379_0_0_11"/>
    <dbReference type="OMA" id="ICLARTG"/>
    <dbReference type="OrthoDB" id="2017453at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="29"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="85" mass="9190" checksum="128FF420C7D99D48" modified="2010-04-20" version="1">MVREPLGPTQRERGNRLGALLRRRRGDRSMVEVATAAGISVETLRKIETGRIPTPALFTVAAIAEVLGVSLDELVRESTAQPAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWU9</accession>
    <name>D3PWU9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5542</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020744.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5542"/>
    <dbReference type="EnsemblBacteria" id="ADD45173">
        <property type="protein sequence ID" value="ADD45173"/>
        <property type="gene ID" value="Snas_5542"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5542"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_28_0_11"/>
    <dbReference type="OMA" id="MAVQATN"/>
    <dbReference type="OrthoDB" id="1204683at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="194" mass="20899" checksum="32434357E87E0EF7" modified="2010-04-20" version="1">MTTTRRGRPRSFDRDAALGRALDAFWRHGYEGTSMATLTEAMGLNPPSVYAAFGGKRELFDAVVAHYQEEKRELMASALSESGSAREAVARLLRVLADDYTDRSHPPGCLVISAAVNCSPAASEVEASLRAHREASKRAIAERIAVDHPARAEALALYVAAVVQGMSTQARDGATREQLRGLADTAMLAWPDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX05</accession>
    <name>D3PX05_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5599</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020800.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5599"/>
    <dbReference type="EnsemblBacteria" id="ADD45229">
        <property type="protein sequence ID" value="ADD45229"/>
        <property type="gene ID" value="Snas_5599"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5599"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002554_3_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013587">
        <property type="entry name" value="Nitrate/nitrite_sensing"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08376">
        <property type="entry name" value="NIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="521"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="764" mass="83440" checksum="1342414D9C35D2F0" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX53</accession>
    <name>D3PX53_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5647</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020848.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5647"/>
    <dbReference type="EnsemblBacteria" id="ADD45277">
        <property type="protein sequence ID" value="ADD45277"/>
        <property type="gene ID" value="Snas_5647"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5647"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_2_11"/>
    <dbReference type="OMA" id="ANPWART"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025828">
        <property type="entry name" value="Put_sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13796">
        <property type="entry name" value="Sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Sensor" evidence="3">
        <location>
            <begin position="30"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="233"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="433" mass="46458" checksum="2681078B8B5A0DDB" modified="2010-04-20" version="1">MSHTSIPISQTTGARIGRRFKQLGLVFPLLGLSIAGLVMFVLFVVGMPLVFLTVGIPLVVGAVGATRGLCNAERFIYRVGFGVEIDRPYRPWPKGNVAKVLLELAKDASTWRNFGWQAVNFTLGFIVFVTYIALLGGALMALIQPFLWLGLPDVFDTYYGFISYDSFALAMTYGVILGGMNFVAWWVGGDAMLNGYARLAGVMMRANKSQKLQRRVVELTESRADTVDSSAAELRRIERDLHDGAQARLVALGMSLGMAEEILTSDPQAAAKLLAEARENSGAALSEIRDLVRGIHPPVLADRGLGGAVEALALAHPLPVTVETNLPGRPPEPVESAAYFAVAEALTNVAKYAQATEVFVRIGYFGTRLGITVRDNGRGGATVTPGGGLDGVTRRLAAFDGVVTIRSEPGGPTIVAYEIPCELTVRPSLTMDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXI6</accession>
    <name>D3PXI6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3658</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018887.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3658"/>
    <dbReference type="EnsemblBacteria" id="ADD43316">
        <property type="protein sequence ID" value="ADD43316"/>
        <property type="gene ID" value="Snas_3658"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3658"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_2_3_11"/>
    <dbReference type="OMA" id="HLVHGYL"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="5"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="152"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="296" mass="31143" checksum="8640929CB83F2873" modified="2010-04-20" version="1">MPAAIAVGYDGSPSSRRAIDWAADEARLRDRELIIVTVHLTLSAPPPPAEDEPDPSADRQAVRDMLNAAKRDLAERSPRLKVEAELISAATAGAGLVAGSDRWELLVLGERGEGGFAGILVGSTSTQVSAHARCPVVVVRGPGGETGPNAGRVVIGVDESEHSREAVRFGLREARLYQVPATLVHAWRHPMATRDGYLASGLGDRQAMADRALTTISEALSGIHEDFPDVPVKRMAVHGGARQVLLDQSMGARMLVVGSRGHGGFAGLLLGSTSQALLHHADAPVAIVRSARPTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXP3</accession>
    <name>D3PXP3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3716</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3716"/>
    <dbReference type="ESTHER" id="stanl-d3pxp3">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43373">
        <property type="protein sequence ID" value="ADD43373"/>
        <property type="gene ID" value="Snas_3716"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3716"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046066_2_0_11"/>
    <dbReference type="OMA" id="RGGMIRI"/>
    <dbReference type="OrthoDB" id="1573721at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="30"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="26801" checksum="A78455F77E1F466C" modified="2010-04-20" version="1">MAAGSTLIAGSAMADPDTSSGKTRRPRPTIVLVHGAFTDASSWHGVIGRLQDAGYTVIAPANPLRDLTSDSAYIAAVVKSVKGPVVLAGHSYGGAVITNAAREADNVTGLVYLAAFAPDEGESPGSISADYPETPIGQSLAPLPLPDGTADLLIAPDKFHHVFAQDIPAADAARLASAQRPIAEAAFGGKTGEPAWKSLPSWFLVATEDHAIHPDAQRDMAERAHAKKTVKVASGHAVSLSHPGKVAALIRTAAKQARDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXY7</accession>
    <name>D3PXY7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Iron permease FTR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5686</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020887.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5686"/>
    <dbReference type="EnsemblBacteria" id="ADD45316">
        <property type="protein sequence ID" value="ADD45316"/>
        <property type="gene ID" value="Snas_5686"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5686"/>
    <dbReference type="eggNOG" id="COG0672">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077905_0_0_11"/>
    <dbReference type="OMA" id="GIPKLRW"/>
    <dbReference type="OrthoDB" id="2018349at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005381">
        <property type="term" value="F:iron ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="PTHR31632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="287" mass="31063" checksum="A30A225606B9A897" modified="2010-04-20" version="1">MFDTLFATFLIGLREGLEATLIVSILVAYLVKSDKRKYLPHVWGGVAAAVVITVIAWAVQHYGTRELTPDGRELFEAITSILAVCFVTWMIFWMRKAARRIAGELRAKLEQAIKMGPVAVVTMAFLAVIREGLETAVILETQTTASQGGTEALLAAIVGIAVSVAIGVGIYYGAVKINLSRFFTWTGVLLIFVAAGIFKYGIHDFQEVGALPGLNTFAFDISGWYAQDSWYGNLLEGMFNITATPSVVETIAWVAYVVPALTFFLWPSGKKPAPAAAPKSEETASAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXZ5</accession>
    <name>D3PXZ5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase domain protein hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020895.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5694"/>
    <dbReference type="EnsemblBacteria" id="ADD45324">
        <property type="protein sequence ID" value="ADD45324"/>
        <property type="gene ID" value="Snas_5694"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5694"/>
    <dbReference type="eggNOG" id="COG0546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_19_2_11"/>
    <dbReference type="OrthoDB" id="1484726at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="211" mass="22573" checksum="8A6C6E06D13D0ABC" modified="2010-04-20" version="1">MAKHLVWDWNGTLIDDFAAVVEATNLAIGTVGGQQLDAATHRERFFRPVADFYSELAGRELPPAEFAELDKLFHQHYHSKLAEHGLTVDARAAIAAWPGTQSLLSMWFHNDLVPLVTEHGLVEHFARIDGLRETVGGNSKHPYLVAHLEALGIDATDCVLIGDSVDDHVAAATAGASCVLYAGGFTSPTRLRATGAPVAESLTEAVALALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY67</accession>
    <name>D3PY67_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020967.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5766"/>
    <dbReference type="EnsemblBacteria" id="ADD45396">
        <property type="protein sequence ID" value="ADD45396"/>
        <property type="gene ID" value="Snas_5766"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5766"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_0_2_11"/>
    <dbReference type="OMA" id="MQLLGAC"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="332" mass="35679" checksum="A6AA80BB9BBF8750" modified="2010-04-20" version="1">MTPTTVLVTGADRYLAGRLVARLTADERVKRVFGIDTDSLDGNGDLSRILTEERVDTVVHAAVAASAVRAGGRTAQKESNVLGTMHLLAACQRAESVRRVVVKSSVAAYGASARDPAVFTEDTELRAAPRGEFASDVAEVEAYARGFARRRENASVTVLRLAPLLGPTSDTSLTRYFSLPVVPTVLGYDPRVQFLHIEDALDVLHKVTLDDHRAPRGRPDVYNVAGPGALLLSQSIRRAGRVAAPTPELLLRGFAAVAKGRGLVDFSLDQLDFLKFGRVVDCGHLTQTYRITPRPTSEAFDDFVTGHALMSVLGGESITGASARDKRSDSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYX9</accession>
    <name>D3PYX9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020979.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5778"/>
    <dbReference type="EnsemblBacteria" id="ADD45408">
        <property type="protein sequence ID" value="ADD45408"/>
        <property type="gene ID" value="Snas_5778"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5778"/>
    <dbReference type="eggNOG" id="COG0510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076339_0_0_11"/>
    <dbReference type="OMA" id="SMTFWQF"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="76"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="316" mass="34554" checksum="35D2985AE0FCE49D" modified="2010-04-20" version="1">MSEFMSPEQLADRTERALTAAAEAGRDLGLEVTEPTVLYDSFSVVVHLKPSPVVVRMPTVLPTFLTDLDTQSQRQRLELDVAGWLARQGLPVVTPSPLVPAEPVRRNGFSMTFWQFVEHDQSAEPDYVANAAAAAKLHHNLRDYPGQLSFMSVLDMIPSCLDELGAMPELIDAADLDRARAEWELLEPVLGSPEGFARAFPDAEVRPIHGDSPPFNMIPTADGLLYSDFEDPTLGPVEWDLTLVGPDGEAAYNEAAQALGMRTLDERLLAVLTSTRMLQVVACLAMVPQMPPMLDGLKEAMEHWRNLPLAGGLGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYY3</accession>
    <name>D3PYY3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Copper resistance protein CopC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Snas_5782</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020983.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5782"/>
    <dbReference type="EnsemblBacteria" id="ADD45412">
        <property type="protein sequence ID" value="ADD45412"/>
        <property type="gene ID" value="Snas_5782"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5782"/>
    <dbReference type="eggNOG" id="COG1276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_330063_0_0_11"/>
    <dbReference type="OMA" id="MLRGPYE"/>
    <dbReference type="OrthoDB" id="1753926at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046688">
        <property type="term" value="P:response to copper ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032694">
        <property type="entry name" value="CopC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007348">
        <property type="entry name" value="CopC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008457">
        <property type="entry name" value="Cu-R_CopD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014755">
        <property type="entry name" value="Cu-Rt/internalin_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34820">
        <property type="entry name" value="PTHR34820"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04234">
        <property type="entry name" value="CopC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05425">
        <property type="entry name" value="CopD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049577" evidence="10">
        <location>
            <begin position="36"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="393"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="617"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="655"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="685"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="726"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="domain" description="CopC" evidence="11">
        <location>
            <begin position="36"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="CopD" evidence="12">
        <location>
            <begin position="647"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="258"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="503"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="259"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="279"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="298"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD45412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="869" mass="89158" checksum="F3DCEA44D4632DA2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ04</accession>
    <name>D3PZ04_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransf_33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5803</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5803"/>
    <dbReference type="EnsemblBacteria" id="ADD45433">
        <property type="protein sequence ID" value="ADD45433"/>
        <property type="gene ID" value="Snas_5803"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5803"/>
    <dbReference type="eggNOG" id="COG4301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049766_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017804">
        <property type="entry name" value="MeTrfase_EgtD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018005">
        <property type="entry name" value="UCP018005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_33" evidence="4">
        <location>
            <begin position="19"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="319"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="364" mass="40500" checksum="424D31E402744BE5" modified="2010-04-20" version="1">MKPYVLIHCDYSEYTAALRADARSGLFGQDLSLPSRWCFDGRGRRLFGRLAAGSHSRLFRAEAEVLTDCATEFAEYTRARHLIQLGPAGSVPPLLLADSLIAAGKLTAVSSLDTPHAEVPEYPAGFPRLDLRHVIADALRRLPELPDPPRLIHCPAAGFATLDRGERLRLLTLLRDRCEPGDHLLVAAPLAEVPGGSAEFFDDPAGLGAEFNRNVLNVVNHTLDADVTCTAFEHVVSTPRPDRLELRLRARVGLRIELRTLGFHIDVDQGRELRTFRLFGLSAETLSAELERTGFTVTESRHDRRELVTLALAEAALTVRPSRARSRSSRRRPGSRSPARSPRPPRSPRCRRSGRRSWEPRRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ47</accession>
    <name>D3PZ47_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4253 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5847</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5847"/>
    <dbReference type="EnsemblBacteria" id="ADD45476">
        <property type="protein sequence ID" value="ADD45476"/>
        <property type="gene ID" value="Snas_5847"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5847"/>
    <dbReference type="eggNOG" id="ENOG5032XD0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_852355_0_0_11"/>
    <dbReference type="OMA" id="WATGELY"/>
    <dbReference type="OrthoDB" id="1887623at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025349">
        <property type="entry name" value="DUF4253"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14062">
        <property type="entry name" value="DUF4253"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4253" evidence="2">
        <location>
            <begin position="219"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="35990" checksum="4E77861E2D612174" modified="2010-04-20" version="1">MLGDAAPLPETETVAEPGPEPEPEPTAAVEPEAGEPSASATEAEPDEVDKTVVPPQEYFTPSRPKRELLDLEPPPQPKDEPPQTPETLPLDVSGSPRAALRNAGITVPHMQQIVQLGDVRLWAFGVRADEALGWWLQIRQVHEKTGWLPVLLGSPDDWLDNGEGVLHEGDAELERMTELDAETLLHDKAAEAGEPPRGVPILPTRGDSDFAVPKSDGLIGLVEAEHSWQIPALLPWKGSTNWELYGAEHATILKHWHERHEVELVSMTWDILELYVPNPPSAEEDALDTAREVHAYCPDLMAAGVPTLDDLAVHMVRSRAWYFRWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZA0</accession>
    <name>D3PZA0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1878"/>
    <dbReference type="EnsemblBacteria" id="ADD41574">
        <property type="protein sequence ID" value="ADD41574"/>
        <property type="gene ID" value="Snas_1878"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1878"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103066_1_0_11"/>
    <dbReference type="OMA" id="GVERFEY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="41"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="158" mass="17170" checksum="ACCD7641E92A35E5" modified="2010-04-20" version="1">MSRKPVVVNIADAEVLEGGNPMNLLADADVSDGAFSISSGTITAGADNARPHFHRRSWEVFCVVDGTLELLLDDEIVRVEAGGIAAVPPGVTHAFGATPQADVSALVFITPGVRRFDYFRLLPAILRGEIPKAELDDMHHRFDVHFVDSTLWDAHRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZB5</accession>
    <name>D3PZB5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">YD repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1893</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017160.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1893"/>
    <dbReference type="EnsemblBacteria" id="ADD41589">
        <property type="protein sequence ID" value="ADD41589"/>
        <property type="gene ID" value="Snas_1893"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1893"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000672_1_0_11"/>
    <dbReference type="OrthoDB" id="1639867at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003284">
        <property type="entry name" value="Sal_SpvB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022044">
        <property type="entry name" value="TcdB_toxin_mid/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022045">
        <property type="entry name" value="TcdB_toxin_mid/N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03534">
        <property type="entry name" value="SpvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12255">
        <property type="entry name" value="TcdB_toxin_midC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12256">
        <property type="entry name" value="TcdB_toxin_midN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01341">
        <property type="entry name" value="SALSPVBPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="TcdB_toxin_midN" evidence="6">
        <location>
            <begin position="662"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="domain" description="TcdB_toxin_midC" evidence="5">
        <location>
            <begin position="867"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1826"/>
            <end position="1845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2241"/>
            <end position="2366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2248"/>
            <end position="2292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="2510" mass="275008" checksum="F11BDC694D35A696" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZL0</accession>
    <name>D3PZL0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1988</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017255.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1988"/>
    <dbReference type="EnsemblBacteria" id="ADD41684">
        <property type="protein sequence ID" value="ADD41684"/>
        <property type="gene ID" value="Snas_1988"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1988"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_0_11"/>
    <dbReference type="OMA" id="ADIGFMR"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="301" mass="33490" checksum="CFE915BB151801E6" modified="2010-04-20" version="1">MFDPRQLRTFREVVRTGSYSAAARRLGYTQPAITQQMRALEREAGTVLFTRVGRRMRLTEAGQALSKHAEVILENLADAHGQMDAYSRLRAGTVRLCAFPSASATLVPDALARITASHPGVHVELHEDEPPESLHRLVHGECDVTLAFTYPGLREAVPEEVVEIPLLEDQLTVVLPVGHRLARRQTVKLAELSQERWIAGCLRCRANLLHECAEQGFAPRIAFTTDDNLVVQSLVARGLGIAMMPGLVFNFLRHRRIAVRALEPASRRQVFAYLLREHRDIPATSLLVDELKVAAANRTGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZP2</accession>
    <name>D3PZP2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4129 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3924</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3924"/>
    <dbReference type="EnsemblBacteria" id="ADD43579">
        <property type="protein sequence ID" value="ADD43579"/>
        <property type="gene ID" value="Snas_3924"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3924"/>
    <dbReference type="eggNOG" id="ENOG50331S3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_703797_0_0_11"/>
    <dbReference type="OrthoDB" id="1778058at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025403">
        <property type="entry name" value="DUF4129"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13559">
        <property type="entry name" value="DUF4129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048731" description="DUF4129 domain-containing protein" evidence="3">
        <location>
            <begin position="27"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4129" evidence="4">
        <location>
            <begin position="305"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="392" mass="41715" checksum="9D3882DCD8798445" modified="2010-04-20" version="1">MLVVALGFAVLAWLVASATLSGHRLASPGVPEGVPSEVAEHLPKDLYSEFPAGVDLRSADAADLPPGLLDKLGEELSSEELAKLSQVLSDDLLLELAKRHLGEFSPGELQKLWDSLDSDRREQLLDELAGELTQDDVDKYRDELTPELYDELSDHVGGAEPEPSDTPGGESGEPEPSSSGAESSGESSPTASAQPSTALESSAKDQAADKDPEGPPGWLRELGEFTLLALKWLVILGLVALAGYLLYRIGAALFGWWPRRREKPALVVPEPEEPRPEVEVLREAVAEGLSDVEAAADPRRGVIDCWQRLERAAAAAGLARLASETPGELVARVMAAANVDAEALTELADTYRRARYGPHAIGEDLRQRAVAALAAVDAQLAAAQPAEPVEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q010</accession>
    <name>D3Q010_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conserved TM helix repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5911</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021110.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5911"/>
    <dbReference type="EnsemblBacteria" id="ADD45539">
        <property type="protein sequence ID" value="ADD45539"/>
        <property type="gene ID" value="Snas_5911"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5911"/>
    <dbReference type="eggNOG" id="COG0668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049564_0_1_11"/>
    <dbReference type="OMA" id="FGVWGPN"/>
    <dbReference type="OrthoDB" id="1896788at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008910">
        <property type="entry name" value="TM_helix"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05552">
        <property type="entry name" value="TM_helix"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="279" mass="30027" checksum="C31CFB2A771490C9" modified="2010-04-20" version="1">MDISQSFQTLMNQIAGFLPTALVFVATIIIGWIVAKVLRKVVTKLLARVGLDRAAERGGLRRFTGKYTMSEMVGLLVYAAVWLFTLQLGFGWFGTNPVSTMINSVIAFLPQVFVALIIMVVAFAIANMVFDLVSSAMSSVSYGRPLARVAQVMIIAIAAVAALNQIGVATTVTMPVLITVLAMIAGVVVVGVGGGLIAPMRSRWERILNSAEAEAGNLKTQMSNRQSSPEFGQQAYTSQQYSQEGADTQQQQQYQQQTGGGQQYYTPPTEQPPQPPTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q044</accession>
    <name>D3Q044_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Trans-hexaprenyltranstransferase</fullName>
            <ecNumber evidence="3">2.5.1.30</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5946</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.30" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5946"/>
    <dbReference type="EnsemblBacteria" id="ADD45573">
        <property type="protein sequence ID" value="ADD45573"/>
        <property type="gene ID" value="Snas_5946"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5946"/>
    <dbReference type="eggNOG" id="COG0142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_2_3_11"/>
    <dbReference type="OMA" id="CEGQALD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036422">
        <property type="term" value="F:heptaprenyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="322" mass="34453" checksum="B885408AF23BF688" modified="2010-04-20" version="1">MEFVDPELEASVSRRLEVIEKRLQEVIDSGDAFLTEAASHVLKAGGKRFRPMLSVTAAHFGDPDAHGVIESSLVMELTHLATLYHDDVMDEAAMRRGAPSANSRWSNSIAILSGDYLFAVASELVAELGSETVREQARTFSRLVHGQIAETVGPPEGVDPVDWYLRVLTDKTGSLIATAARLGAQFAGAPTSVVDAVAEYGETIGVAFQLSDDLLDIASDGDTSGKVQGLDLMEGIPTLPVLYAQVGDDTSPRLRELVSKPVAQEDLEETLELLRSSAAMKQARKTLDEFGERAKAVAGSLPAGSTRDALTGMCDYMVARSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q052</accession>
    <name>D3Q052_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021152.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5954"/>
    <dbReference type="EnsemblBacteria" id="ADD45581">
        <property type="protein sequence ID" value="ADD45581"/>
        <property type="gene ID" value="Snas_5954"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5954"/>
    <dbReference type="eggNOG" id="ENOG5031R9K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111492_0_0_11"/>
    <dbReference type="OMA" id="IRKEYAW"/>
    <dbReference type="OrthoDB" id="1812124at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019660">
        <property type="entry name" value="Put_sensory_transdc_reg_YbjN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10722">
        <property type="entry name" value="YbjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="159" mass="18191" checksum="A58959BA69BE7B9B" modified="2010-04-20" version="1">MEDLLTELDVEWERTGTKSYVITLPGVHKLKTLCNLIEEDHALRVEAFVVRCPEENQEAVWRFLLRRNASLYGVSYSIDDNGDVYLTGRVPLSCVDGTELDRLLGSVLTYADEVFDRVLELGFATSIRREWAWRISRGESTRNLAAFEHLRPADEESSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q077</accession>
    <name>D3Q077_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021177.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5980"/>
    <dbReference type="EnsemblBacteria" id="ADD45606">
        <property type="protein sequence ID" value="ADD45606"/>
        <property type="gene ID" value="Snas_5980"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5980"/>
    <dbReference type="eggNOG" id="ENOG5032IA4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_929534_0_0_11"/>
    <dbReference type="OMA" id="WIRTATW"/>
    <dbReference type="OrthoDB" id="922446at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="304" mass="34246" checksum="389148EBED0F6885" modified="2010-04-20" version="1">MQTPCAAFLRVYEPLAAFSDERAALWREYAEAGQAVSAREGPAIQRKLVYEAMNPEWDILPRVPEQAYVLDTEDGPLICPWELNERSAAAVRGIGDQVPRNLVDAFAPRRLTMMAGAMSAGPDARGDSDAGPCWHEHVAMWHVPTKWFACVESSERELVLEPGKRGLRYRVPMARARRRARRAYGILQTSLGRSNPVAVSVRQVSEWLSVFHPRSMVEVDYGGLVWVLSDADLRGDDSPQLVHDGLTALARGDVVAAGRGYEQLMRRWRVIRLRERSNLWTKTLTYTPKTGNISVFPTCRLNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0G1</accession>
    <name>D3Q0G1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2001"/>
    <dbReference type="EnsemblBacteria" id="ADD41697">
        <property type="protein sequence ID" value="ADD41697"/>
        <property type="gene ID" value="Snas_2001"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2001"/>
    <dbReference type="eggNOG" id="ENOG5031VKH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_993620_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032724">
        <property type="entry name" value="DddA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14428">
        <property type="entry name" value="SCP1201-deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="286" mass="31108" checksum="17028B39C4C9CDFC" modified="2010-04-20" version="1">MGSIEELTAAVRAALSTIAEGKTLTDKSRAALVDGTAALTGISRGSTSYRLRTMLEALTAAIQATERAEDVEAAVLDAMDAYLSEIAGGNAPARAGPKAPEPKQPGGSSSPRARDGRIDFRALLERLKAQGVVGLEGRSDDPIPDFDPKKQNPACYQGLAPRQKGKPVRGNLFFPDGRRWNDVALESSRGEPAFDLNIIKPEYRSLSPARGHLEGNVAAWMRSTFHQEMVLYINESPCRKHGKGCLYTLEHFLPRGYVLHVWSRNDRGEWRGNTFRGSGEAFTEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0K3</accession>
    <name>D3Q0K3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cobalt transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2044</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017310.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2044"/>
    <dbReference type="EnsemblBacteria" id="ADD41739">
        <property type="protein sequence ID" value="ADD41739"/>
        <property type="gene ID" value="Snas_2044"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2044"/>
    <dbReference type="eggNOG" id="COG0619">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056469_6_0_11"/>
    <dbReference type="OMA" id="IITLAYY"/>
    <dbReference type="OrthoDB" id="1479665at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="264" mass="28117" checksum="7B8AAC5A52C6F76B" modified="2010-04-20" version="1">MITAAPLAPPTAAISRFNPVAKLAPVLVITAMLVLVTDPVTPALMLAVELAALTVSGIHVGRFLGRARLLLFGAGAVVLVNAMYAKPGGEVYLDVGPVHVTETSVETGFALGLRVLAIAIPGILALAATDPTDLADSLVQQLRVSPRFAIGALAALRLLPLLGEEWRLITMARRARGVDANWNPWKRLRLFASATFALLVAAIRRGIRLATAMDARGFDSGTPRTSARPQTVRARDWVLIAATMVFCVTVVAMSVWFGTFRTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0K9</accession>
    <name>D3Q0K9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2050"/>
    <dbReference type="EnsemblBacteria" id="ADD41745">
        <property type="protein sequence ID" value="ADD41745"/>
        <property type="gene ID" value="Snas_2050"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2050"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_7_6_11"/>
    <dbReference type="OMA" id="GREVMYR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="84" mass="9054" checksum="6C7E33F0F05D11CA" modified="2010-04-20" version="1">MRALAAPTRIAIVTELSKGPQCVHEIVDALDAPQPLISQHLRVLRGAGVVRGERRGREIAYALTDEHIAHIVADAIHHAGEAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0L4</accession>
    <name>D3Q0L4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017321.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2056"/>
    <dbReference type="EnsemblBacteria" id="ADD41750">
        <property type="protein sequence ID" value="ADD41750"/>
        <property type="gene ID" value="Snas_2056"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2056"/>
    <dbReference type="eggNOG" id="COG2329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127577_1_0_11"/>
    <dbReference type="OMA" id="DPRHWCL"/>
    <dbReference type="OrthoDB" id="1909149at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="121" mass="13183" checksum="A1CD978CDACACDBD" modified="2010-04-20" version="1">MLVVNRFQVTDVEVFRADARAALKALSARPGFVAGHCGGSVDEEETWVLVTRWDSVGSYRRALSAYDVKMYATPLLARALPEASAFEVNLEAGPDGDVVEHDSDRSAQPWRGSTDDGAARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Q7</accession>
    <name>D3Q0Q7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017364.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41793">
        <property type="protein sequence ID" value="ADD41793"/>
        <property type="gene ID" value="Snas_2099"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2099"/>
    <dbReference type="eggNOG" id="ENOG5031S8F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111671_1_1_11"/>
    <dbReference type="OMA" id="YVAMESF"/>
    <dbReference type="OrthoDB" id="1942143at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021607">
        <property type="entry name" value="DUF3224"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023159">
        <property type="entry name" value="SO1590-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11528">
        <property type="entry name" value="DUF3224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159238">
        <property type="entry name" value="SSF159238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="132" mass="13768" checksum="1C739703EE344AAC" modified="2010-04-20" version="1">MRASGTFIVADFTPSPVPSPTIETATPVGLATMGKQFEGEVTGRATTLFTAAFDQSTGTGTYVAMESFEGSLHDRSGTFNFAHSATTTGEDRQHELFVIVPGSGTGDLAGITGSGGIAVDPDGTHRIWFDYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0R0</accession>
    <name>D3Q0R0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2102"/>
    <dbReference type="EnsemblBacteria" id="ADD41796">
        <property type="protein sequence ID" value="ADD41796"/>
        <property type="gene ID" value="Snas_2102"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2102"/>
    <dbReference type="eggNOG" id="COG1357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029034_0_0_11"/>
    <dbReference type="OMA" id="DTRFTKA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13576">
        <property type="entry name" value="Pentapeptide_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="485" mass="54077" checksum="384354E676C2ED32" modified="2010-04-20" version="1">MGLRDLGWGVDDGVVTEKRWPWVGAMVGIVVAIAVAVGVSWVLLKPGDIEDERARIAAVQAVAAIGFGVGGLGTLLLFVRRQWHQERIAADDRREADRQHERELAKAADDRHDATERRITELYMTAAEQLGHDKAPVRLAALHALDRLGQNEANHRQVIVDIWCSYLRQPFTPPARFVAADDAEPKAAPDEDHPGLSLETEADPADLEYEVRATAQRLLISHLKDPRDDDDRTDEPPPVKPDGFWNPSRIDLTGATLINANFTSCWLPTTTFTRTRFLGRAWFSGARFYGARLYGGAVFEEARFEGGAWFSGVRFDGDANFGMARFEGRASFSRAQFGQLAWFARAQFDGDTRFTDARFDGDTRFTKARFEGSVSFSRAQFGQNAWFDKTRFDEIAAFDQAWFDGDTRFTKARFAGDAGFIRVQFTEDSRFDGVIAVLPSAEGHTHVWPAGWVLEPDPEGPTDWGRLVQEPTPTEPEPDSPTAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0R8</accession>
    <name>D3Q0R8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017375.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2110"/>
    <dbReference type="EnsemblBacteria" id="ADD41804">
        <property type="protein sequence ID" value="ADD41804"/>
        <property type="gene ID" value="Snas_2110"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2110"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_170329_1_0_11"/>
    <dbReference type="OMA" id="TCPVVHF"/>
    <dbReference type="OrthoDB" id="2031076at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsnC_trans_reg" evidence="1">
        <location>
            <begin position="6"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="77" mass="8285" checksum="6B553ADF00E1B7AE" modified="2010-04-20" version="1">MVQAYILIQTEVGKARDVALSIIDIEGVVKVDSVTGPYDVVVLTQARTVDELGKMVVSKVQQVSGITRTLTCSVVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q141</accession>
    <name>D3Q141_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4140</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019362.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4140"/>
    <dbReference type="EnsemblBacteria" id="ADD43791">
        <property type="protein sequence ID" value="ADD43791"/>
        <property type="gene ID" value="Snas_4140"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4140"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="EPLRTYY"/>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="30"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="322"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="63"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="370" mass="40314" checksum="4F510EB5035E9E34" modified="2010-04-20" version="1">MNEPTTVAAGTAAAGETVLEVDNLVKHFPIRAGVVFKKKIGAVKAVDGVSLSLRKGETLGVVGESGCGKSTLAKLLVGLERPTSGGIRVKGEDITRLGRKGLHRLRRNVQMVFQDPYTSLNPRMTVGDIIGEPFVIHPDVVPKSGRRKAIQDLLDVVGLNPDHINRYPHQFSGGQRQRIGIARALALKPEILLCDEPVSALDVSIQGQVINLLEELQDELGLSYIFIAHDLSVVRHIADRVAVMYLGSVAELGTEDEIYESPMHPYTQALLSAVPVPDPKAREHKAEIILEGDVPSPANPPSGCRFRTRCFKARQEWAKTATPEQKDSTSYADQVPDNCRDEQPLLQIRPGADHPNACHYAAPRDVLHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q151</accession>
    <name>D3Q151_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4150"/>
    <dbReference type="EnsemblBacteria" id="ADD43801">
        <property type="protein sequence ID" value="ADD43801"/>
        <property type="gene ID" value="Snas_4150"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4150"/>
    <dbReference type="eggNOG" id="ENOG5031D67">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091328_0_0_11"/>
    <dbReference type="OMA" id="LMRTLQM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021403">
        <property type="entry name" value="DUF3043"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11241">
        <property type="entry name" value="DUF3043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="244" mass="28385" checksum="3E0E904CEE949FD6" modified="2010-04-20" version="1">MWSGHDLPVSLVSVPALFKRKSRDESTEDVEQPESAVEDLRETKKVRDKSDPTPKRKQPSKKRPPKNPPKTYKEAREQAKAGKPTTKEAKRELAAERRAERLRVADGQDKGDPLFDQYHMPRDKGPERLLVRDVVDARFSIGQYFFIIAIVIMLFSNPAYGMIYDFVVFAWIAVLLLFVIDSVLLCRKVKRLVKKRFPKTTQRMGGLYWYAVSRSIMFKRMRMPKPRTRVNSKTPEEQLGKQFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q178</accession>
    <name>D3Q178_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6034"/>
    <dbReference type="EnsemblBacteria" id="ADD45658">
        <property type="protein sequence ID" value="ADD45658"/>
        <property type="gene ID" value="Snas_6034"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6034"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_20_3_11"/>
    <dbReference type="OMA" id="GTTGWIH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="2">
        <location>
            <begin position="4"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="489" mass="53359" checksum="42426174D9251E8D" modified="2010-04-20" version="1">MPPTQVLVTGAGPTGLTLACGLAAQGIAVTVVDAAPGPATTSRANILHARGVEVLTRVGALGDLPARSLAPVGMTMHARGKALTTMRFAPDTRESTQALFISQAAVEAELRRRLDELGVPIQWNRRVLAATPDTDGVTVDFGDNAPIRTDWLVGCDGARSTVRGLSGIDFPGVPVVEQFLLADVRADWDRDRSTSAGWFHTDGMLLAIPMRDNDGGLWRLMADVPKTSEHLEPEQIIARFERLLPERTGETGVRIREALWTSVFRIQRRLADSYRAGRVLLAGDAAHIHSPIGGQGMNTGIGDAENLAWKLALVAHGRADESLLDTYTAERRPLATEVLRRTTANTRVLVGDGPVSRALRDWLFVPLLNLPAVQRDPNRVPAVGHLPRRPTRRPGQNPATGRPDPGPRLRNRRRHPHPPLPAPELRVGRAVPQRFPHGGHGRGHRPPTPRRGCHGASRPDERRRHPRDPPRRPPRLARRRPGQAGTVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q195</accession>
    <name>D3Q195_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6051</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6051"/>
    <dbReference type="EnsemblBacteria" id="ADD45675">
        <property type="protein sequence ID" value="ADD45675"/>
        <property type="gene ID" value="Snas_6051"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6051"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="LMVATDH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="35783" checksum="C22A8C0C2EB2D86B" modified="2010-04-20" version="1">MELRDIEIFLTLAEELHFGRTATRLRVTPARVSQSIAKQERRIGAALFDRSSRSVVLTAIGERLRDDLSEGYQRIQQGLATATSAAKGLTGALRLGVLGPVIHELAPITRTFGARHPECELSFREIPLTDPFRLLRDGGVDIAVLWLPVEEPDLTVGPVVFRENSVLAVAVNHPLARRDSVSLEDLADQVVVQAASPVPDYWVDALSPRHTPSGKPIKRGPKVSTNEESLAAIASGQAVAPAHETDARYYARPDIVYVPIHDAKPQRWALIWRTTGETELIRAYVRVAREITGGLTIVSRNAVGARRVTGEHGQSTNLSERPCPATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1F3</accession>
    <name>D3Q1F3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021304.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6109"/>
    <dbReference type="EnsemblBacteria" id="ADD45733">
        <property type="protein sequence ID" value="ADD45733"/>
        <property type="gene ID" value="Snas_6109"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6109"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043786_0_0_11"/>
    <dbReference type="OMA" id="WNASEND"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="339" mass="38367" checksum="BF215F6B6658F61F" modified="2010-04-20" version="1">MDISKLHPEDTAAIDELWEMWRLGVERDTASPKLRTYSKTIFLAQLGNIHPDEHNEFRVARVDGRIVGFVQIGVPLRDNKHAAHIHGTVHPEYRRRGIGTALLTQATQSSRDQGRTLQTSNTLETLPDGPLCDHAGRDFLLHHGFAVGLPMRLRALRLSDSEGEIERELLDESWPKAEGYELVQWTGATPAEHVDGAAALASRLMSDVPQGDLDFEEVIFDAERYLRKESVDFQSGWDFTCTYVRHVESGELVAHSVIAVSSDHPSVGNQWITLVHPDHRGHRLGMIVKVENHRLLRRTKPEVTWIKTGNAESNEHMVAINEQLGFTELCRYIAFQREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1M2</accession>
    <name>D3Q1M2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">DNA repair protein RadA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">radA</name>
        <name evidence="8" type="ordered locus">Snas_0150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the RecA family. RadA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015441.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0150"/>
    <dbReference type="MEROPS" id="S16.A04"/>
    <dbReference type="EnsemblBacteria" id="ADD39870">
        <property type="protein sequence ID" value="ADD39870"/>
        <property type="gene ID" value="Snas_0150"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0150"/>
    <dbReference type="eggNOG" id="COG1066">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018264_0_1_11"/>
    <dbReference type="OMA" id="FELMRLA"/>
    <dbReference type="OrthoDB" id="505485at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01498">
        <property type="entry name" value="RadA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004504">
        <property type="entry name" value="DNA_repair_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00416">
        <property type="entry name" value="sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RECA_2" evidence="7">
        <location>
            <begin position="69"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Lon-protease-like" evidence="5">
        <location>
            <begin position="358"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="RadA KNRFG motif" evidence="5">
        <location>
            <begin position="256"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="98"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD39870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="465" mass="47872" checksum="E86298F9447024B8" modified="2010-04-20" version="1">MAKSPKTVYACSGCGHSVPKWVGKCPDCGEWGTMEAAVAMSGPAAAPRRAATARPAIPAQSIAQVSAKQAQAKSTGVDEFDRVLGGGLVPGGVVLIAGEPGVGKSTLLLDVAHRYAAAGHGRTLVATGEESAAQVRLRADRIGALHPDLMLAAETDLASVLGHIDDVKPGLLILDSVQTVTTSDVDGVPGGVTQVRAVAAGLISVAKERGITTILVGHVTKDGNIAGPRVLEHLVDTVVHFEGDRHSTLRLLRGVKNRFGPADEVGCFDMTEDGIVGLTDPAGLFLAESPDEPVPGTCVTVTMEGRRAMLVEVQALVGGSAKDGTIPRRTVSGLDYARLNMALAVLHQRGHVKCLDREVYAATVGGMKVMEPAADMAIILAVASSVSGAPVSADIVAIGEAGLTGAIRRVTGVPRRLAEAARLGFRHALVPPGCAEGAPKNMTVTEVSTIAEATRIAAQRWAARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1M7</accession>
    <name>D3Q1M7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0155"/>
    <dbReference type="EnsemblBacteria" id="ADD39875">
        <property type="protein sequence ID" value="ADD39875"/>
        <property type="gene ID" value="Snas_0155"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0155"/>
    <dbReference type="eggNOG" id="ENOG5034A2X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1288237_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="214" mass="23315" checksum="B4CA3C30A641C1E1" modified="2010-04-20" version="1">MPRNASAGWTVMRQRPPRRALTRLSGFVLMGALATCITWLIFITEPAQLSSGASNPAAKMPTFMAIAVVVSVLLAAAPALRPPRLAANHYGLAVRPGAFRTVLLPWVHVEEVTAVAVPGRRHPDAYILVACDDYLGRTTGDRPRFLDQAVLREANRAADGRVGDFDLAVRLADFTDTPEAILERIASYAPDHVDVNNQLDDPIEDRDAKKKPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1T5</accession>
    <name>D3Q1T5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0214</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015504.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0214"/>
    <dbReference type="EnsemblBacteria" id="ADD39933">
        <property type="protein sequence ID" value="ADD39933"/>
        <property type="gene ID" value="Snas_0214"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0214"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_0_11"/>
    <dbReference type="OMA" id="VHDHERI"/>
    <dbReference type="OrthoDB" id="961884at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="14"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="395"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="478" mass="50762" checksum="3B07A476847E0A34" modified="2010-04-20" version="1">MDSLFPSLWTGERKTALRFGDRELDYPRLAAVASALADRLRTESRVALWAEPELTTAVATVAALLAGVPVVPINPKIGERELEHILADSAPGLVLAAPGAAMPEALRSLPRVDIALDTDGPAAQPSEPDEAAPALIVYTSGTTGPPKGAVLPRRAITATLDGLAEAWRWTGDDVVVHGLPLFHVHGLVLGILGPLRRGGTAHHLGRFSPSAVTQALEGDGTILFGVPTMYHRLAETVDTDTALAAALSRARLLVSGSAALSLPDHERLTAATGQRVVERYGMTETLMNTSVRIDAEPKPGTVGIPLPGVELRLVDDNGGVITDSDGETIGEIQVRGPNLFTEYLNRPEATAAAFTDGWFRTGDMATRDGDGDLRIVGRQSTDLIKSGGFKIGAGEIENALLDHPDVTEAAVTGEADPDLGERVVAWIVPADPHRPPTTEALADHVAVKLAPHKRPRVVHFRESLPRNDMGKIMKRALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1V0</accession>
    <name>D3Q1V0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017388.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2123"/>
    <dbReference type="EnsemblBacteria" id="ADD41817">
        <property type="protein sequence ID" value="ADD41817"/>
        <property type="gene ID" value="Snas_2123"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2123"/>
    <dbReference type="eggNOG" id="ENOG5031XEM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_182347_1_0_11"/>
    <dbReference type="OrthoDB" id="2079019at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="64" mass="7294" checksum="9BC648C92528520A" modified="2010-04-20" version="1">MAKALFGHVGQAPDRRMLDEVTKLRAKVRSLEFEVTRLRADNDRLITEVASTEEINRLSEPVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q241</accession>
    <name>D3Q241_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate-binding protein PstS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2217</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Part of the ABC transporter complex PstSACB involved in phosphate import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PstS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2217"/>
    <dbReference type="EnsemblBacteria" id="ADD41908">
        <property type="protein sequence ID" value="ADD41908"/>
        <property type="gene ID" value="Snas_2217"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2217"/>
    <dbReference type="eggNOG" id="COG0226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034528_1_1_11"/>
    <dbReference type="OMA" id="FPYPVYA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005673">
        <property type="entry name" value="ABC_phos-bd_PstS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002756">
        <property type="entry name" value="PstS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00975">
        <property type="entry name" value="3a0107s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049463" description="Phosphate-binding protein PstS" evidence="4">
        <location>
            <begin position="20"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="5">
        <location>
            <begin position="34"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="350" mass="37045" checksum="56DA96202986A9CC" modified="2010-04-20" version="1">MTTKARVKILPLMAVGALALGVAACGSGGGSGEGLTGELTAAGASFPDAFYQDVIGKYLDNEAPDANIEYDPTGSGTGKEKFSEDLVDFAGTDSLVSDEDGIEADSFYYVPTVAAPITIPYNLKDVKELKLSPDTLADIFQAKITKWNDPAIAKDNPDAKLPSTEITVAHRSDGSGTTSNFTTYLDDASDKWKLGAGDTVEWPKNSKAGEKNTGVADIVKKTEGAIGYVDLADATELKLTPAQIKNKDGEFVEPTLEAATAALEGAEVNEDLSYNPLNATGAEAYPITAPTFLLVKAEYDDAEKGKLVKGFVEYVLTDGQKAAEDNNFAPLPKELADKALKQLDKVKTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q270</accession>
    <name>D3Q270_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2247</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017508.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2247"/>
    <dbReference type="EnsemblBacteria" id="ADD41937">
        <property type="protein sequence ID" value="ADD41937"/>
        <property type="gene ID" value="Snas_2247"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2247"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="ADHFPDE"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="13"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="247" mass="26373" checksum="DD96F14A25DE4F8F" modified="2010-04-20" version="1">MNTQTSVRAATAVRLTEVTKKYRGGVTALDHVSLPVPRGTFLAVMGPSGSGKSTLLHCAAGLDVPTDGSVHIGDTEISGLSETKRTMLRRERVGFVFQAYNLVPSLSVSDNITLPLRLAGARPDHDWLRTLVAHIGLEGLLNRRPAELSGGQQQRAAVARALVARPDVVFADEPTGALDLHTAGEVLDLLRRLADDFGQTVVMVTHDPGAAARAHEAVVMADGRIRDVVATPSAEKLAQLLTTLERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q272</accession>
    <name>D3Q272_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017510.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2249"/>
    <dbReference type="EnsemblBacteria" id="ADD41939">
        <property type="protein sequence ID" value="ADD41939"/>
        <property type="gene ID" value="Snas_2249"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2249"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_2_11"/>
    <dbReference type="OMA" id="TFPLWYR"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025828">
        <property type="entry name" value="Put_sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13796">
        <property type="entry name" value="Sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="330"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="420" mass="44778" checksum="0EE8ABA205157202" modified="2010-04-20" version="1">MTRDTSKPGPVWAVLRRALVATKWMLAGMGTSMLAVLGWALVVLIAGLSLLGVGLLLLRPALLVIRRIADLERARLNRMGKPVTASYAELPYPPLQVLRALAEDPSNRRDLAWLVLHGSYGFLLASLALQAPVNVLRELSFPLWWTLVPPEESNALNGFIDISTWTGAWLVFATAPLWFILWLVVTPLLTGPQALPGVRLLNPHPDIDLSARLAQLTATRAAALDAHAVELRRIERALHDGAQNRLVGVAVLVGAARQALRRDPDHADAVLERAQSTAEDALAELRSVVRSILPPVLENRGLSGALSALAADSPVPCHLQVDVPVRCPVSVEATAYFAVAEALTNAAKHSRATRVDITVVRVGDRLTATVTDDGTGGAEPDTGTGLSGIRRRVAAHDGTTTITSPPGGPTVIEVELPCGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2C4</accession>
    <name>D3Q2C4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4208</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019428.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4208"/>
    <dbReference type="EnsemblBacteria" id="ADD43857">
        <property type="protein sequence ID" value="ADD43857"/>
        <property type="gene ID" value="Snas_4208"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4208"/>
    <dbReference type="HOGENOM" id="CLU_2652707_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="76" mass="8057" checksum="E09B3318458BB354" modified="2010-04-20" version="1">MGKRSRVHINVEAVKAALTAQGAVGVCAQARRIGITREAWGRICAGKLKTTPRTETLARIVAATGLNYSSVIAHND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2E5</accession>
    <name>D3Q2E5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4229</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019449.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4229"/>
    <dbReference type="EnsemblBacteria" id="ADD43878">
        <property type="protein sequence ID" value="ADD43878"/>
        <property type="gene ID" value="Snas_4229"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4229"/>
    <dbReference type="HOGENOM" id="CLU_2013866_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="123" mass="13526" checksum="BCFD29569B770BAA" modified="2010-04-20" version="1">MLYPHTPIVYPSEYRSDSDGNAVRWPSLEGVPVPANIQPHASAVTTVEAGKGGPSQQTRVEAVAYLSGTFCPALDAYAALDWDGWRWVMVGDPIDHQSPDGTLRMWRAEIRRDRALADAPRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2J3</accession>
    <name>D3Q2J3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylated-DNA-(Protein)-cysteine S-methyltransferase DNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019497.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4277"/>
    <dbReference type="EnsemblBacteria" id="ADD43926">
        <property type="protein sequence ID" value="ADD43926"/>
        <property type="gene ID" value="Snas_4277"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4277"/>
    <dbReference type="eggNOG" id="COG3695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_52_5_11"/>
    <dbReference type="OMA" id="MRTDSAD"/>
    <dbReference type="OrthoDB" id="1928537at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_binding_1" evidence="1">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="104" mass="11357" checksum="C3CE8E08F799C9C1" modified="2010-04-20" version="1">MDDAVLPDFAEKVLEAAESIPPGKVMTYGDIAEWIGEGGPRQVGRVMSHYGGPVPWWRVVRSDGVILPGHEARALAAYRDEGTPLRRGGSATRIDMARARWNGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2V9</accession>
    <name>D3Q2V9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6239"/>
    <dbReference type="EnsemblBacteria" id="ADD45860">
        <property type="protein sequence ID" value="ADD45860"/>
        <property type="gene ID" value="Snas_6239"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6239"/>
    <dbReference type="HOGENOM" id="CLU_2588045_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="80" mass="9362" checksum="12083600DD49868F" modified="2010-04-20" version="1">MNPNDHIIFDPTEFDRRLDTIATHRTQGHEFEIGQFSDDRWYCDPADLSYSPTVWATRAEALNYADLTVEMNRVRITNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2X1</accession>
    <name>D3Q2X1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6252</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6252"/>
    <dbReference type="EnsemblBacteria" id="ADD45872">
        <property type="protein sequence ID" value="ADD45872"/>
        <property type="gene ID" value="Snas_6252"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6252"/>
    <dbReference type="HOGENOM" id="CLU_1905477_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="133" mass="14588" checksum="A2F0695611CDD226" modified="2010-04-20" version="1">MTTTTPKGHYTVNTAGIYTYFVVYVNDGGRGVSEMSLGKPITTFEQIRQIARVIEADNGITGVTVTWYQLLSGPEANNRLEDALRDVHNFLSRALDNAAADRRSGFYSQKSILDTLTGNVREARATLGALTDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Y9</accession>
    <name>D3Q2Y9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0240</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoU family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0111 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015530.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0240"/>
    <dbReference type="EnsemblBacteria" id="ADD39959">
        <property type="protein sequence ID" value="ADD39959"/>
        <property type="gene ID" value="Snas_0240"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0240"/>
    <dbReference type="eggNOG" id="COG1392">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086031_0_1_11"/>
    <dbReference type="OMA" id="LFNGKYD"/>
    <dbReference type="OrthoDB" id="1837604at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018445">
        <property type="entry name" value="Put_Phosphate_transp_reg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01865">
        <property type="entry name" value="PhoU_div"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD39959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="209" mass="23714" checksum="64B79C9FA6F3D178" modified="2010-04-20" version="1">MRFSLRPQDDAFYKFFIEAAENIVKGTAILAELGEAEVDTQSVSERLVEVEHANDEITHELYNKINSTFVTPLDREDMYQLGSQLDDVMDHIEAAGNLVYLYGLSELPSLPREMVEIVDVLKAQAAITVEAMPKLKGMDPSLRDYWIECNRLENDGDRAYRMLLVRLFSGEYEALTVLKLKEVADELEKACDAFEHVSNTVETISVKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3B6</accession>
    <name>D3Q3B6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2268</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017528.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2268"/>
    <dbReference type="EnsemblBacteria" id="ADD41957">
        <property type="protein sequence ID" value="ADD41957"/>
        <property type="gene ID" value="Snas_2268"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2268"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_0_11"/>
    <dbReference type="OMA" id="MKPTIYS"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001761">
        <property type="entry name" value="Peripla_BP/Lac1_sug-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00532">
        <property type="entry name" value="Peripla_BP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="338" mass="36558" checksum="D5F79F74224DF63E" modified="2010-04-20" version="1">MSTSRGARQPTIKEVARLAGVSPMTASRTLAGGRNVRPDLQERVLAAVRELGYYRNENARSLRPGQPSGLIGIAITNLANPYYGNFALGVEEVAAEHGRRIILGNTGEDDARERQLVSDFIGRQVDGLILVPVSGDAAHLKPERLGEVPLVLASRRVPGLDVDTVLLDDVGGAYRGTVSLLDAGHTRIGFLGNRSSVFTGERRFRGYEQAMTERGVPVDPAIVARDQQDVAAASLAAKAMLDRDEPPTAIFSANNRNTIGALREIGRRIREGRSGPRPAIVSFDDFELSELMPVPVTVIDHDARLLGREAATLLFSRLDEDVAVPARTVELPVSIEYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3J0</accession>
    <name>D3Q3J0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbonic anhydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2345</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2345"/>
    <dbReference type="EnsemblBacteria" id="ADD42031">
        <property type="protein sequence ID" value="ADD42031"/>
        <property type="gene ID" value="Snas_2345"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2345"/>
    <dbReference type="eggNOG" id="COG0288">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053879_4_2_11"/>
    <dbReference type="OMA" id="LPAHIQY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049511" evidence="3">
        <location>
            <begin position="22"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="232" mass="24206" checksum="73CDBE728E107F04" modified="2010-04-20" version="1">MVMLFVAGMLVLADLPPPLPGSTETTDTQLLTGATTMLIPPHLPARARAALRALLDGNRRFISGSPTYSRDISSARAAAGGQRPIAAVFTCVDSRVTAESLFDCDFGQLIVVRTAGHVPDRAAVGSLRFAVDALAVPLVIVLGHERCGAVKLAVDTLRDPNRPEQLDYLVEQLSDPVAKALSDGAADPCATAMRLQIDQTVAVLKGDPGVAAASIVGARYDLDNGTVSVHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3K6</accession>
    <name>D3Q3K6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2362</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017618.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2362"/>
    <dbReference type="EnsemblBacteria" id="ADD42047">
        <property type="protein sequence ID" value="ADD42047"/>
        <property type="gene ID" value="Snas_2362"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2362"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_11"/>
    <dbReference type="OMA" id="NGGQLIC"/>
    <dbReference type="OrthoDB" id="1209997at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="26520" checksum="79BC226A42F99C81" modified="2010-04-20" version="1">MDLQLSRKIALVTGASRGIGLATVRALEAEGVRVVAASRSISDGLRSTGAITIPADLSHPDAPAELVAATIEKLGGLDILVNNVGGGDGAQLGGLLDFDDATWRDTFELNFFAAMRTARAAMPGLLASGGVIVNISSIGAKVPGGNPLPYASAKAALDAFGKSMSEEFGPRGVRVKTVSPGPVRTAMWESPDGHGAKLAESLGISHEALLQAMPGQLGLTTGRLVEPEEVAAFVTYLTSPLADSIVGSDHLIDAGAVKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3P9</accession>
    <name>D3Q3P9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4319</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019537.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4319"/>
    <dbReference type="EnsemblBacteria" id="ADD43966">
        <property type="protein sequence ID" value="ADD43966"/>
        <property type="gene ID" value="Snas_4319"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4319"/>
    <dbReference type="eggNOG" id="ENOG5032VCE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121293_0_0_11"/>
    <dbReference type="OrthoDB" id="1733975at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="174" mass="19820" checksum="D4BB37D9E571E838" modified="2010-04-20" version="1">MGQMADRLAALVVTAFSPDGQIEGSYGAAAGANIRFNGNSYRHYTERGLGHQLSRMAVLVWIAHQRGHDATVAEVTGQPVSRRQETWDARRRRFREEQAETESEGMSTGGLVYFRNTGMRDWHIVIRDGTLSKLDEPEFVKEFLSGYAALSLDYRHKMTKLRTKHYGPDIWMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3S7</accession>
    <name>D3Q3S7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019565.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4347"/>
    <dbReference type="EnsemblBacteria" id="ADD43994">
        <property type="protein sequence ID" value="ADD43994"/>
        <property type="gene ID" value="Snas_4347"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4347"/>
    <dbReference type="HOGENOM" id="CLU_2248466_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="104" mass="10948" checksum="C3AA08D7F73DA460" modified="2010-04-20" version="1">MNRVELARSLHDAISRVRGVSRLGGGSGVMEVSTQYAYGRVAGVSVAGARVEAQVVVTELPVVAVAERVHKAAARVLRASGDDRPVRVVVTDIDINSLADAGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q428</accession>
    <name>D3Q428_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Activator of Hsp90 ATPase 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021484.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6293"/>
    <dbReference type="EnsemblBacteria" id="ADD45913">
        <property type="protein sequence ID" value="ADD45913"/>
        <property type="gene ID" value="Snas_6293"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6293"/>
    <dbReference type="eggNOG" id="COG3832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108923_2_0_11"/>
    <dbReference type="OMA" id="WHPYAID"/>
    <dbReference type="OrthoDB" id="1914312at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="16094" checksum="99B4BA4473A7D701" modified="2010-04-20" version="1">MSFPNTIERTLELAHPPEKVWAAITTAEGLASWFGNTASIDLRPGGDFRMTWEGDFEADMRVERVEKPTVFAYTWPIDGLPKDDPRRTYVEFTLEPVDGGTRLTVRESGFAQLPEEVRRKAIEGNTGGWKSELGELVEYLDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q431</accession>
    <name>D3Q431_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HipA N-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6296</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HipA Ser/Thr kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021487.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6296"/>
    <dbReference type="EnsemblBacteria" id="ADD45916">
        <property type="protein sequence ID" value="ADD45916"/>
        <property type="gene ID" value="Snas_6296"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6296"/>
    <dbReference type="eggNOG" id="COG3550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030167_4_0_11"/>
    <dbReference type="OMA" id="FCQAMGL"/>
    <dbReference type="OrthoDB" id="1293681at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012893">
        <property type="entry name" value="HipA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017508">
        <property type="entry name" value="HipA_N1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13657">
        <property type="entry name" value="Couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07804">
        <property type="entry name" value="HipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03071">
        <property type="entry name" value="couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Couple_hipA" evidence="4">
        <location>
            <begin position="15"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="HipA_C" evidence="3">
        <location>
            <begin position="154"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="408" mass="44548" checksum="4222D04639F7BAE2" modified="2010-04-20" version="1">MTHTDIHDLPTVTQADVYKDNRLAGYLERTTDGIQFGYLREYLESGGPPVATTLPLRDEPLVTLAGAVPPFFAGLLPEGRRLNALRHAVKTSSDDELSLLLAIGADAIGDVSVIPKGHNPQPVPTFLEIDDPHQADFTEVLAASLGTSPDRVGIPGVQDKVSARMISMPVRGSTGPGILKLNPPEFPSVVENEAFFLEAARRSGIDVAPSALIHDGQGVPGLLVQRFDRVVTDTGEFRSLPAEDACQVLGRYPAAKYSLTSEEIAAGLISVTRAEAVAAMSLLRQFVFAYLTANGDAHAKNFSILGSVSGEWKISPAYDLPTSYLYGDYTLALSIGGRRREDVTRATFADFGQHLKLKPRATHRVLDELIERTDLWINDLDTLPFATQQVRKLKRAIQYRRKQLTARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q527</accession>
    <name>D3Q527_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019647.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4431"/>
    <dbReference type="EnsemblBacteria" id="ADD44076">
        <property type="protein sequence ID" value="ADD44076"/>
        <property type="gene ID" value="Snas_4431"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4431"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062658_5_0_11"/>
    <dbReference type="OMA" id="IRRETFA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="39"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="188" mass="20945" checksum="40736C086C948673" modified="2010-04-20" version="1">MNHVFEVRDSQTVWSGFRFGMVRDEVAMPGGGTAERVYLDHPGAVVVAALDAQDRIALIHQYRHPVRQRLWELPAGLRDVEGEDPAEAAARELAEEADTRAARISHLFTFHPTPGCSNERIEIFLARDLSPVPDAERHVRTDEEADLSLRWWDLDEAVAAIFDGQITNGCTIAGLLAVSQLRARTHSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q570</accession>
    <name>D3Q570_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA (adenine(58)-N(1))-methyltransferase TrmI</fullName>
            <ecNumber evidence="4">2.1.1.220</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4474</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>adenosine(58) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methyladenosine(58) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10365"/>
            <dbReference type="Rhea" id="RHEA-COMP:10366"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74491"/>
            <dbReference type="EC" id="2.1.1.220"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer composed of a dimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.220" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4474"/>
    <dbReference type="EnsemblBacteria" id="ADD44119">
        <property type="protein sequence ID" value="ADD44119"/>
        <property type="gene ID" value="Snas_4474"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4474"/>
    <dbReference type="eggNOG" id="COG2519">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025402_0_0_11"/>
    <dbReference type="OMA" id="VVYPKDA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031515">
        <property type="term" value="C:tRNA (m1A) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016429">
        <property type="term" value="F:tRNA (adenine-N1-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014816">
        <property type="entry name" value="tRNA_MeTrfase_Gcd14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133">
        <property type="entry name" value="PTHR12133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08704">
        <property type="entry name" value="GCD14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017269">
        <property type="entry name" value="GCD14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51620">
        <property type="entry name" value="SAM_TRM61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="112"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="266"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR017269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR017269-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="294" mass="31864" checksum="BC5F217B5C77811C" modified="2010-04-20" version="1">MSNVRTGPFREGDRVQLTDPKGRMHTVVLESGKTFHTHRGGISHDDLIGQPEGSVVSSTANTRYLALRPLLTDFVLSMPRGAQVIYPKDSAQIIAEGDIFPGARVIEAGAGSGALTCSLLRAVGETGHVYSYELRPDFAEIARNNVETFWGGPPKQWTLTNGDFAECAETGVDRIVLDMLSPYAVLDAVERALVPGGVLIGYIATTTQMSDLVEALRERGGFTEPRAFECMVRGWHLEGLAVRPDHRMIAHTAFLVITRKLAPGVTAPTRQRKPSKGAEAYAARKAQNATPPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5A5</accession>
    <name>D3Q5A5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cytosolic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4509</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019725.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4509"/>
    <dbReference type="EnsemblBacteria" id="ADD44154">
        <property type="protein sequence ID" value="ADD44154"/>
        <property type="gene ID" value="Snas_4509"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4509"/>
    <dbReference type="eggNOG" id="COG3553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127482_1_0_11"/>
    <dbReference type="OMA" id="PARYIKQ"/>
    <dbReference type="OrthoDB" id="1858344at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014543">
        <property type="entry name" value="UCP028291"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09981">
        <property type="entry name" value="DUF2218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028291">
        <property type="entry name" value="UCP028291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="95" mass="10504" checksum="DA436F456644B4F6" modified="2010-04-20" version="1">MPAAHARVATPRAARYLKQLSSHFGHKADSTYDEHSGHTDFGFGQCRMTAETDALVIDVEAPDAEMLGRVEHVVADHLERFASREGLSVEWRPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5U1</accession>
    <name>D3Q5U1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015811.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0525"/>
    <dbReference type="EnsemblBacteria" id="ADD40240">
        <property type="protein sequence ID" value="ADD40240"/>
        <property type="gene ID" value="Snas_0525"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0525"/>
    <dbReference type="eggNOG" id="COG4587">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084465_0_0_11"/>
    <dbReference type="OMA" id="TIVYWYL"/>
    <dbReference type="OrthoDB" id="1552415at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010390">
        <property type="entry name" value="DUF990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06182">
        <property type="entry name" value="ABC2_membrane_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="259" mass="28620" checksum="E1F2A868EA379246" modified="2010-04-20" version="1">MTPRIAYLGTRFKALLAYRFEIIIWLIGPLLQMLLLATVWRAVYDGRSTVDGVSLAVMTTYVTISTIHSLIAHDDMDDWVHERVNTGGVGVDLLRPLPFMEQTLWGSVAQLGIKLLMIVVVLPVGAVFAGLSAPAHLGLYLIAAVLAWLVNLCMYLLLSSIVFWTLEVHGLNFMYFVVNAFLSGALVPLWFMPDWLATALSWLPFQAIVFTPASIYVGQLTGTAAWQAIGVQFTWLVLLSATAVLVWRRAVRKTVVQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q654</accession>
    <name>D3Q654_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thiamine pyrophosphate protein TPP binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2548</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017800.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2548"/>
    <dbReference type="EnsemblBacteria" id="ADD42229">
        <property type="protein sequence ID" value="ADD42229"/>
        <property type="gene ID" value="Snas_2548"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2548"/>
    <dbReference type="eggNOG" id="COG3960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_1_2_11"/>
    <dbReference type="OMA" id="MIEREAN"/>
    <dbReference type="OrthoDB" id="391134at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009028">
        <property type="term" value="F:tartronate-semialdehyde synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009436">
        <property type="term" value="P:glyoxylate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006397">
        <property type="entry name" value="Glyox_carbo_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968:SF14">
        <property type="entry name" value="PTHR18968:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01504">
        <property type="entry name" value="glyox_carbo_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="5">
        <location>
            <begin position="6"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="3">
        <location>
            <begin position="192"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="4">
        <location>
            <begin position="389"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="570" mass="61893" checksum="6E4AD0733C2160CA" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6F9</accession>
    <name>D3Q6F9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FHA domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019773.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4558"/>
    <dbReference type="EnsemblBacteria" id="ADD44202">
        <property type="protein sequence ID" value="ADD44202"/>
        <property type="gene ID" value="Snas_4558"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4558"/>
    <dbReference type="eggNOG" id="COG1716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031794_0_0_11"/>
    <dbReference type="OMA" id="WTTITLH"/>
    <dbReference type="OrthoDB" id="1632705at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="146"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="233" mass="25755" checksum="7303D5A96CA5FEB4" modified="2010-04-20" version="1">MKTCPNRHSVHDHLEYCEECGSRVESTPTRLFQPAPPPPPQQQVQLWTCSHCHTQQGLSRYCEACGEPNPRHPEYADEPTDEIEQQYRAPEPPPPPPMATARITVTATADRAFFDRMQSHDGPDAGTLMFPAVYPPRTFTLERPQIFIGRRSRSRGIEPDIDLSGAPEDSGVSHAHAAIINAEGRWCVVDVGSSNGTYLNMAPEPIPANTPTLLNHGDRIHLGAWTTLTVSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6I7</accession>
    <name>D3Q6I7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gamma-glutamyltransferase</fullName>
            <ecNumber evidence="1">2.3.2.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4586</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.2.2" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4586"/>
    <dbReference type="MEROPS" id="T03.013"/>
    <dbReference type="EnsemblBacteria" id="ADD44230">
        <property type="protein sequence ID" value="ADD44230"/>
        <property type="gene ID" value="Snas_4586"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4586"/>
    <dbReference type="eggNOG" id="COG0405">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_366771_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102953">
        <property type="term" value="F:hypoglycin A gamma-glutamyl transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103068">
        <property type="term" value="F:leukotriene C4 gamma-glutamyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="760" mass="77803" checksum="F204C667491BC63F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6J1</accession>
    <name>D3Q6J1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019805.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4590"/>
    <dbReference type="EnsemblBacteria" id="ADD44234">
        <property type="protein sequence ID" value="ADD44234"/>
        <property type="gene ID" value="Snas_4590"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4590"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_13_2_11"/>
    <dbReference type="OMA" id="YTLGGQH"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="50"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="35807" checksum="1237DB947B319789" modified="2010-04-20" version="1">MKRANLAPESAVRSLQRLAPPWPGREHRVGQQRLFVRETPATSDDAEPALYVHGLGGSSQNWTDLADVLSDRFAGQAIDLPGFGHSEPTARYTIPALAQQVAAWITQSGRGPVHLIGNSLGGAISVYVAATRPHLVRTLTLISPAMPFADVRRSTQSRLLPLLALPRADRIAARAMAGLSPEKIVEQVVANCWAEPDTVPPQRRVEAIAEVRRRLNVPWNTQVYVRTFRSLVGHFLQSYLPGSSSLWRLATQVTAPTLVIWGKQDRLVDVRLAPQVARAVTDSRLLILDRVGHVAMMERPEVTGRAVVGMLDELEAAEPYTDADVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7C2</accession>
    <name>D3Q7C2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2717"/>
    <dbReference type="EnsemblBacteria" id="ADD42393">
        <property type="protein sequence ID" value="ADD42393"/>
        <property type="gene ID" value="Snas_2717"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2717"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_10_1_11"/>
    <dbReference type="OMA" id="GFFLHTD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="130" mass="14237" checksum="CFA8314810202808" modified="2010-04-20" version="1">MHLIALVVAEYDPAIEFFTRILGFELVEDSPSQTNDGRPKRWVVVRPPGAETGILLARADGEKQRAEIGNHAAGRVGLFLRVDDFDASYKHMVDSGVTFTSEPRTEPYGQVAVFVDIAGNKWDLLGPAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7H8</accession>
    <name>D3Q7H8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4677"/>
    <dbReference type="EnsemblBacteria" id="ADD44320">
        <property type="protein sequence ID" value="ADD44320"/>
        <property type="gene ID" value="Snas_4677"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4677"/>
    <dbReference type="HOGENOM" id="CLU_3367487_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="35" mass="3796" checksum="8C0069A05F8759C7" modified="2010-04-20" version="1">MPQLFLPVDLVTSVPSLPSEIHTMVVTSNPQLFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q833</accession>
    <name>D3Q833_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome c biogenesis protein transmembrane region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0826</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016109.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0826"/>
    <dbReference type="EnsemblBacteria" id="ADD40538">
        <property type="protein sequence ID" value="ADD40538"/>
        <property type="gene ID" value="Snas_0826"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0826"/>
    <dbReference type="eggNOG" id="COG0785">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053225_2_1_11"/>
    <dbReference type="OMA" id="TSLTPCM"/>
    <dbReference type="OrthoDB" id="1617952at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD" evidence="2">
        <location>
            <begin position="23"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="249" mass="25830" checksum="E71C209C4FCE390C" modified="2010-04-20" version="1">MTSPFADLATNGPLLVAMGVAALAGLVSFLSPCILPLVPGYVSYVTGLSGADLETPSSRGRVAAGCALFIAGFTAVFTFLSFAVTSLSNALATSTVWLERGAGVLIIVMGLAFLGVIPGFDRLIRVQKLPRAGLFAAPVLGAVFALSWTPCLSPTLTAVLALGATQDGTARGVTLAITYCLGLGLPFLLFGLGFRKMMDVFTFFKRHSRTLTRVGGIAMVLIGLALVTGLWTEAMNWLRATVGPGEVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8D0</accession>
    <name>D3Q8D0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent pyridine nucleotide-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2828</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018075.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2828"/>
    <dbReference type="EnsemblBacteria" id="ADD42504">
        <property type="protein sequence ID" value="ADD42504"/>
        <property type="gene ID" value="Snas_2828"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2828"/>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003291_4_0_11"/>
    <dbReference type="OMA" id="IATYPYH"/>
    <dbReference type="OrthoDB" id="1149616at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028202">
        <property type="entry name" value="Reductase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14759">
        <property type="entry name" value="Reductase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="7"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Reductase_C" evidence="2">
        <location>
            <begin position="323"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="410" mass="44285" checksum="573753A3F4DCDC51" modified="2010-04-20" version="1">MTTEQTFVIVGASLTGASAAQTLREAGFTGRVVLVGAENERPYERPPLSKGYLLGSEERPTIFVHEEDWYAKHSVELRLGHSAVELDRGARTVRLDNGEQLQYDKLLLATGASPRELDVPGTDLDGIFSLRRVGDSERLQAALRAHSRVAVVGAGWIGLETAAAARELGCEVTVFEPQPTPLHAALGAEMGEFFAELHRRHGVHLRLGSGVSRINGSDGRVTSVVDDNDEEVPADAVIVAVGARPNTELAERCGLSVDNGVLVDASLRTDDADIYAAGDVANPTHPRYQRRVRVEHWDNALHGGQAAAKAMLGQDVDYDRLPYFFTDQYDVGMEFSGWFPPGGYDAVVTRGDVAEQAFYAFWLSGERVVAAMHINQWDDGIAPAQALILGGGAVDAKRLADASVPFDQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8N7</accession>
    <name>D3Q8N7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4838</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020050.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4838"/>
    <dbReference type="EnsemblBacteria" id="ADD44479">
        <property type="protein sequence ID" value="ADD44479"/>
        <property type="gene ID" value="Snas_4838"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4838"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069607_0_0_11"/>
    <dbReference type="OMA" id="AGCYILI"/>
    <dbReference type="OrthoDB" id="1745385at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="286" mass="30130" checksum="0A89574C9D0E3104" modified="2010-04-20" version="1">MSVLEATETATEGRPRRRLLYAELRLMSGRTRNLVGLAILCAIPIVLAIILAVTRPTGGGDGQAPPFFSILYGNGLFVVLTSLMMEMTIFLPMAVCILAGDSIAGEANVGTLRYLLTAPVGRTRLLSVKFASLVIGAIVGVLAVAVTAAIIGLSLFGAGEMLTLSGTTLSFGESIGRVALVCGYVMAMLVSVCAVALFASTLTEQPIGAAVGTLMWIILHQILTSLDALSWLHPFLQTTYWANWSGLMRDPVEWGGVGVGLLSALAYTLVFGSAAWARFTTKDITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8U6</accession>
    <name>D3Q8U6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020109.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4897"/>
    <dbReference type="EnsemblBacteria" id="ADD44538">
        <property type="protein sequence ID" value="ADD44538"/>
        <property type="gene ID" value="Snas_4897"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4897"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142293_0_0_11"/>
    <dbReference type="OMA" id="ESHHYAF"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="130" mass="14548" checksum="59D91EE00753003D" modified="2010-04-20" version="1">MSVQLNHTIVAAKDRSESAEFLADILGLEVGAPMGPFLPVQLHNGVTLDFAQQPPDKEFAPQHYAFLVSEAEFDAAFDKIKRYRLTFWADPRQHLEGEINHHDGGRGVYFLDPSGHYLELITVPYGGWPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8W5</accession>
    <name>D3Q8W5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0863</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016145.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0863"/>
    <dbReference type="EnsemblBacteria" id="ADD40574">
        <property type="protein sequence ID" value="ADD40574"/>
        <property type="gene ID" value="Snas_0863"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0863"/>
    <dbReference type="eggNOG" id="ENOG5032ZD0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100609_0_0_11"/>
    <dbReference type="OMA" id="WRTWHAY"/>
    <dbReference type="OrthoDB" id="1950284at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024486">
        <property type="entry name" value="DUF2617"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10936">
        <property type="entry name" value="DUF2617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="180" mass="19605" checksum="D0375DFA38BB1124" modified="2010-04-20" version="1">MILDLDVPFADSSVNDLRFLDRAPALPVLGALEFPHPVPGGHLTLRLLGASHQAEVWTPEGGVYAETVACLPGEGSPVPASHTTTVGPWSFWFSSQVRALSAEEFSARCAELRSRARDWENTILVGEFPGHPDAMTFLDASSQLPGYGRGWSTVHCYPEEQRMVLTHTVAMPVTEPAFPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q917</accession>
    <name>D3Q917_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphomethylpyrimidine kinase</fullName>
            <ecNumber evidence="7">2.7.4.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0915</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP = 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP</text>
            <dbReference type="Rhea" id="RHEA:19893"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.7"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16892"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-amino-2-methyl-5-diphosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole: step 3/3.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.7" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016197.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0915"/>
    <dbReference type="EnsemblBacteria" id="ADD40626">
        <property type="protein sequence ID" value="ADD40626"/>
        <property type="gene ID" value="Snas_0915"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0915"/>
    <dbReference type="eggNOG" id="COG0351">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020520_0_1_11"/>
    <dbReference type="OMA" id="DNRHTHG"/>
    <dbReference type="OrthoDB" id="461201at2"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00138"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008902">
        <property type="term" value="F:hydroxymethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008972">
        <property type="term" value="F:phosphomethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01169">
        <property type="entry name" value="HMPP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045029">
        <property type="entry name" value="HMP/HMP-P_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004399">
        <property type="entry name" value="HMP/HMP-P_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858">
        <property type="entry name" value="PTHR20858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00097">
        <property type="entry name" value="HMP-P_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phos_pyr_kin" evidence="6">
        <location>
            <begin position="18"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="274" mass="28198" checksum="107EBCEF2BE2EDCD" modified="2010-04-20" version="1">MTTVTTQPPTALTIAGSDSGGGAGIQADLHTFAAHAVHGTSVVTSVTAQNTLGVTDVHPVPPETVSAQLDAVLSDFDVRAVKTGLLPDETILSIVAERAEAGDLPELVVDPVLVAASGDKLFTGDFGAYLERLSPHTIVFTPNIHEAQALLGGEITGLDDMREAARALARYGSQAVLVKGGHGKDPEKATDVLWTQGQILELSAPRVDTPNTHGTGCTLASAIAARIAHGHPVAQAVGGAKRYLTEALTAAASWRLGAGPGPVHHHHGRKSTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q949</accession>
    <name>D3Q949_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0947</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016229.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0947"/>
    <dbReference type="EnsemblBacteria" id="ADD40658">
        <property type="protein sequence ID" value="ADD40658"/>
        <property type="gene ID" value="Snas_0947"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0947"/>
    <dbReference type="eggNOG" id="COG0510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_673745_0_0_11"/>
    <dbReference type="OMA" id="WDWERFA"/>
    <dbReference type="OrthoDB" id="565681at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="410" mass="44856" checksum="987CAC0C5A7AA966" modified="2010-04-20" version="1">MTSGRVATTDDRSRRADYLEEVTALLFPPAPCGGREHAEAEYIVVPSLRRPRVLVPAESRRLAAAALRRYTRPATLSARLKRDAAVLAVVTGTDKLALPHRMALPLSGENIAGHLSQVLDTEVHLGIHIGPARANRKPVLQILDDDAETIGFAKLGTTGLTRELVAAETTALRTLAGINLSNLRIPKIVHSGTWGPHAVLIQEALPGWRRPVRTDPDRLTDAMTELATCLGVEDSLLSRSDYVACLDRRLAVVAERPGTDAATLVDAARQLLERNRDQLLRFGSWHGDWSPWNMSMLAEDILLWDFERFTSGVPMGFDAVHYALQRDIVTRAADPTTAVLSLLARSHRLLKPFGVEPQAARVTVLLYLVDLATRYLTDRQAEAGAPLGALGRWLLPTLLRHVAAEGGIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q980</accession>
    <name>D3Q980_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0979</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016260.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0979"/>
    <dbReference type="EnsemblBacteria" id="ADD40689">
        <property type="protein sequence ID" value="ADD40689"/>
        <property type="gene ID" value="Snas_0979"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0979"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_22_1_11"/>
    <dbReference type="OMA" id="ATKMIAS"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="14"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="113"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="293" mass="31227" checksum="DDAD9CBC65AE5B58" modified="2010-04-20" version="1">MTARPPGVVAEAFEAQRDRLRAVAYRVLGSHADAEDVVQEAWMRLVRQDDSAIDNLAGWLTTVVGRISLDLLRSRQARPETAYGQQFAELMVTPDEGPAPDEQAVLADAVGLALLVVLDSLTPSERLAFVLHDMFAVPFREIGQILGKSADATKMIASRARRKVRGTGSTVGGGREAHREVVAAFSAAAAGGDFEALLRVLDPDVRLSVDTPDGVVVTLGATKVASGARMFSSGEIARHRDVLVNGVRGQMSWRADGTPLSVIAFTVAEGRIRGIHIVVDPAKLAAIQLPVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q991</accession>
    <name>D3Q991_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2898</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2898"/>
    <dbReference type="EnsemblBacteria" id="ADD42573">
        <property type="protein sequence ID" value="ADD42573"/>
        <property type="gene ID" value="Snas_2898"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2898"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_4_3_11"/>
    <dbReference type="OMA" id="LPGMLFE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="148" mass="16289" checksum="A83EC75B012CFB90" modified="2010-04-20" version="1">MTTPITDNNHHDWRKAMSRTIINPSDLHDPTAFGYSHVNTTEGSPLVFIAGQYDSGDQGTPTSSDFNTQARRAFDNLGKALRAAGLDYDNVVKLGTFIVDHDADKLTTVGKLVHEHWGDRPPAQTLNGVARLALPEMLFEVDAIAIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9A8</accession>
    <name>D3Q9A8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2915</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2915"/>
    <dbReference type="EnsemblBacteria" id="ADD42590">
        <property type="protein sequence ID" value="ADD42590"/>
        <property type="gene ID" value="Snas_2915"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2915"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="INAPITH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048965" evidence="6">
        <location>
            <begin position="30"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="350"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="397"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="6"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="458" mass="47368" checksum="8CA11E47F976EFCC" modified="2010-04-20" version="1">MRKLWVLAALCAAQFMAIVNISVVNVALPAIQKDLDTSLAGLQWVLNAFTICISALTLAGGSLGDRFGRKRVFVTGLAAFIVGTVVCAVSVNLGMLITGRLIQGIAAALLLPGSLSILAQTFTDPAERVRRIGIWAAVSAVGLVIGPVVGGVLIQAFGWPSLFWLCVPLGVTALIATLVFVPESANPEHAAIDPLGQILAMLSLGSLSFGLIRLGDKGWDDTVALIVTGTALVLFVVFIVVELRTRTPMLPVRLFADRSFAAMNFASASLGFGPYTMYAFLALYLQQERDFSALSAGLAFVPMSIATAIVAPLAGRWVGASGPVPAMLAGYGSSAVGLAGVALFDAHTSWFLMGPVFVLIGVGMGLSMTPTTNGAVDAVPRERSGIASATINTTRQTGLAIGIALLGAMVSAQDNFLTGLRLVAAVTALVSLIAVVYILAGRVATRPRTPAEATASAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9C5</accession>
    <name>D3Q9C5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-binding 9 siderophore-interacting domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2932"/>
    <dbReference type="EnsemblBacteria" id="ADD42607">
        <property type="protein sequence ID" value="ADD42607"/>
        <property type="gene ID" value="Snas_2932"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2932"/>
    <dbReference type="eggNOG" id="COG2375">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040923_2_0_11"/>
    <dbReference type="OMA" id="DQWFRLF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013113">
        <property type="entry name" value="FAD-bd_9_SIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007037">
        <property type="entry name" value="SIP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039374">
        <property type="entry name" value="SIP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30157">
        <property type="entry name" value="PTHR30157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08021">
        <property type="entry name" value="FAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04954">
        <property type="entry name" value="SIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="275" mass="30077" checksum="A019282B0D58BEEA" modified="2010-04-20" version="1">MARTNMTSTRVKPETAQLVTLRVLRSQRISPHFVRVTLGDGDIGQFKYLGFDQWFRLFIPVSDDSLSRLPNATKVNLPMYLKYLRIAKTDRPVLRNYSVRAFRPEGPELDVDFVVHGHGDDAGPAATWAQNCKTGDPVAVIDEGCGFNPDASLRRVTLVADESGLPAAAGILASLDADVTGQAILEIPDAADEQELRAPDGVAVTWLPRDGSSEIPGRLALAAAMELPLPAEPFYGWVVGEQQLPTGLRRHWVKNGVPKQNIMFCGYWRTGKAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9M0</accession>
    <name>D3Q9M0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020137.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4925"/>
    <dbReference type="EnsemblBacteria" id="ADD44566">
        <property type="protein sequence ID" value="ADD44566"/>
        <property type="gene ID" value="Snas_4925"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4925"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_17_1_11"/>
    <dbReference type="OMA" id="GLSEMCF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022324">
        <property type="entry name" value="Bacilysin_exporter_BacE_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01988">
        <property type="entry name" value="EXPORTERBACE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="420" mass="42323" checksum="4EFB0FC09A640665" modified="2010-04-20" version="1">MSQAPATPASAPGPARADAPPARPAYRDGAYLRYTAGQSISIVGDQVWYVALSWAAVQLASPAVAGLIMTVSALPRLILLLLGGVYVDRFGPKKLMIGSDLLRVVVSLTAAAIALAAPSIALLVVVGLVFGIVSAVFMPAAGAMGPLLLSKEQQTAGVALRELSGRIALTVGAPLGGLLVAVGGLSLAATVDAFTFALSAWTLWSLRPRQAAKSDRPPAPTGAALKEGLSYLWNHGLVRNLMLAGLLVNLGFVGPMNVGLALLSEARGWGAGGIGYMLAGFGGGAAVSALILLRFKPRRATGLIIAACAALQAVAVFALAVVPTVWLAVAATSATGLVSGVMGVLMGSLVQVNTDDAYRGRVSSVSTVLNYGITPLAVAGSGIAVATAGMTATFAVSAALILAGGLACVARRDLRTAQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9N0</accession>
    <name>D3Q9N0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020147.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4935"/>
    <dbReference type="EnsemblBacteria" id="ADD44576">
        <property type="protein sequence ID" value="ADD44576"/>
        <property type="gene ID" value="Snas_4935"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4935"/>
    <dbReference type="eggNOG" id="COG0748">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1014588_0_0_11"/>
    <dbReference type="OMA" id="FDARFDF"/>
    <dbReference type="OrthoDB" id="1822051at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="245" mass="26799" checksum="BC3F243BF3CC6217" modified="2010-04-20" version="1">MFVAPAELARTLTAGHQPATVQVAWNETMWTVNASADSEGTPLLLLPDADGLTAALRDSRGMDTAVAMRFDDEPPLPCAPWLGSAWVAGWAEPVPESGQRQAALAFSEVNPVPELLDVGQGHTMWRVNVAEVRLQCGDELTDIPAADYAAAEPDPFYPLEVELLLDLYDHHPEVLHALTHRIEHQLPSVRRVAPLRMNRHGIVVDVHCAESVDPRRFLIRHRQGVTCVDQVLASLCRCDCAAAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9S4</accession>
    <name>D3Q9S4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4982</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4982"/>
    <dbReference type="EnsemblBacteria" id="ADD44620">
        <property type="protein sequence ID" value="ADD44620"/>
        <property type="gene ID" value="Snas_4982"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4982"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1991317_0_0_11"/>
    <dbReference type="OMA" id="VEGMHAS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="125" mass="13897" checksum="8C67590BFEE27471" modified="2010-04-20" version="1">MELLCTVYPVGDLETAAAHYLNLGFRDVARPDHDTILLAADESPYVDVMLERHPVEAHLGSGPVFRIEDVEGMHASQPDLNWVGQPVDIPTGKYAIFRDPDGNPIRVVDFTADSGRFASLFRPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA04</accession>
    <name>D3QA04_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_1006</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016287.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1006"/>
    <dbReference type="EnsemblBacteria" id="ADD40716">
        <property type="protein sequence ID" value="ADD40716"/>
        <property type="gene ID" value="Snas_1006"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1006"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037625_0_0_11"/>
    <dbReference type="OMA" id="DELYFIA"/>
    <dbReference type="OrthoDB" id="854536at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="59"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD40716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="489" mass="52665" checksum="CFAF0DC8BBFC44AD" modified="2010-04-20" version="1">MNLALGERRPSPPFATRSILALALAASAVLFALSGRYGFHRDELYFMAAGDHPAWGYVDQPPLTPLLARASTTVFGDTPTGLRVVATLAFAAIVILTAAIARELGARRGGQLLAACCAAVGSFVPAVGHMVSTTTFDILIWLALILTVLHLHRTANPRWWLATGALAGVGLLNKHLIVLLAAVMLVAILITGPRTLLKGRWPWIGVAVAAAIAAPNLIWQATHDWPQLTVASGISAEDGTDNRIMFIPEQLLYVSPLLVPIWLTGWWHLWRDRTTRWLALTYPILCALVLALGGKGYYTLPLLLVLTASGCGPVVTWARHTTWRTAVVIAGVTLTAASTAVMSLPTLPPTQLDIPNAVNKEQGEQVGWPELTAAVATAWNDLPSTTDAVIFTQNYGQASAIAHYGPDHDLPQPFSGHMSYADWGPPPDSATGPVLTVGEFPARFFTDCRRVGRVDSAQVDNEEQGTPILACSGPTRPWSDLWPSLRHFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA05</accession>
    <name>D3QA05_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1007</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016288.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1007"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40717">
        <property type="protein sequence ID" value="ADD40717"/>
        <property type="gene ID" value="Snas_1007"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1007"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015079_0_0_11"/>
    <dbReference type="OrthoDB" id="635734at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="13"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="205"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="669" mass="75454" checksum="DA1EA9D675967F4F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA16</accession>
    <name>D3QA16_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyridoxine/pyridoxamine 5'-phosphate oxidase</fullName>
            <ecNumber evidence="5">1.4.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">PNP/PMP oxidase</fullName>
            <shortName evidence="5">PNPOx</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Pyridoxal 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pdxH</name>
        <name evidence="9" type="ordered locus">Snas_1018</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + O2 + pyridoxamine 5'-phosphate = H2O2 + NH4(+) + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15817"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58451"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O2 + pyridoxine 5'-phosphate = H2O2 + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15149"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 6">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="5 6">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the pyridoxamine 5'-phosphate oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1018"/>
    <dbReference type="EnsemblBacteria" id="ADD40728">
        <property type="protein sequence ID" value="ADD40728"/>
        <property type="gene ID" value="Snas_1018"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1018"/>
    <dbReference type="eggNOG" id="COG0259">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032263_2_2_11"/>
    <dbReference type="OMA" id="PEPNAMV"/>
    <dbReference type="UniPathway" id="UPA01068">
        <property type="reaction ID" value="UER00304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine-phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01629">
        <property type="entry name" value="PdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019740">
        <property type="entry name" value="Pyridox_Oxase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PTHR10851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000190">
        <property type="entry name" value="Pyd_amn-ph_oxd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00558">
        <property type="entry name" value="pdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01064">
        <property type="entry name" value="PYRIDOX_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0288">FMN</keyword>
    <keyword evidence="4 5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="7">
        <location>
            <begin position="39"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="PNP_phzG_C" evidence="8">
        <location>
            <begin position="174"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="193"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <begin position="64"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <begin position="79"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <begin position="143"/>
            <end position="144"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000190-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="214" mass="24789" checksum="F4035F44B80B82CD" modified="2010-04-20" version="1">MKRTVNAEDLSRLRREYDEPDELDLETDPFGWFRRWFDEAATVEPEPNAMVLATVDDQGFPRQRTVLLKSFDTSGFTFFTNYTSDKGVQLTANPKVNLLFGWYRLHRQVIVSGTAKRVPPEESARYFATRPRGAQLAAWASPQSRPIPGRTDLESAFAQAEARFPDEVPVPPHWGGFLVEPRLIEFWQGRRNRMHDRVRYHRESSAWVPVRLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA43</accession>
    <name>D3QA43_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016326.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1045"/>
    <dbReference type="EnsemblBacteria" id="ADD40755">
        <property type="protein sequence ID" value="ADD40755"/>
        <property type="gene ID" value="Snas_1045"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1045"/>
    <dbReference type="HOGENOM" id="CLU_758429_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="323" mass="35037" checksum="7DD7D5E4AF83F6F0" modified="2010-04-20" version="1">MSNEIKEIIDTELPPGTAPVKLDVEAVMRGNRNARMKRRLVGGGAAVASIVAVVALVLSVMTLAPEDRNSDDSTITADDPVIDPDENYFWWGPESEKATDASKAYTEAFWKYVAKEHPEVSLTVSGENAEEESVTKDFADYSFLLAADFALYEGEEWDMPQAASGKPVRERTVLTLFEDFAPDKGGSNGWSSCCGGTLRFRDGDDEKDKVDNFDIQVYPKGSFTKGTEDAMDPAFLGEDVTHDIETVTGPDGEDIQYVAGSTPDDVDGTVHTFERSAIVYRADGSAVAVRAMSNTDRGGNVSDNLSFEDLQGMALAMPDDPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA81</accession>
    <name>D3QA81_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1083</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1083"/>
    <dbReference type="EnsemblBacteria" id="ADD40793">
        <property type="protein sequence ID" value="ADD40793"/>
        <property type="gene ID" value="Snas_1083"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1083"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_4_3_11"/>
    <dbReference type="OMA" id="GFLLWYA"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="8"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="135"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="286" mass="28698" checksum="6B2618372460AA41" modified="2010-04-20" version="1">MLLVGSLVAVNASINDYPIYTAHAIRYALAAVALCAILAVRKPEPVRLNRREVVLLLALAIGGLAVFNVAIAEATHFASSALVGTIVGSGPIVMAILGPLVARSGRPSGQVLVAAVAVTVGTAVATGLGGGDPLGALLAAVALAGEVSFSLLAVPLLPKLGALRVSAYTAVISVPLLLAAGWLIDGPAMLRVPDLGELSAIVYLGLVVTTAGFLLWYDSLPRLGPDRAGLFAGIMPIGAITTMMLLGQGLPSPAEALGAALVVGGILYGVRRTAARVGPVVASQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA89</accession>
    <name>D3QA89_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="4">IMP dehydrogenase</shortName>
            <shortName evidence="4">IMPD</shortName>
            <shortName evidence="4">IMPDH</shortName>
            <ecNumber evidence="4">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">guaB</name>
        <name evidence="11" type="ordered locus">Snas_1091</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + IMP + NAD(+) = H(+) + NADH + XMP</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="4">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 9">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1091"/>
    <dbReference type="EnsemblBacteria" id="ADD40801">
        <property type="protein sequence ID" value="ADD40801"/>
        <property type="gene ID" value="Snas_1091"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1091"/>
    <dbReference type="eggNOG" id="COG0516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022552_2_1_11"/>
    <dbReference type="OMA" id="MGYCGAK"/>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="PTHR11911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0630">Potassium</keyword>
    <keyword evidence="4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="95"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="155"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="4">
        <location>
            <begin position="340"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="4">
        <location>
            <begin position="363"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="4">
        <location>
            <begin position="387"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="4 5">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4 5">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <begin position="249"/>
            <end position="251"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <begin position="300"/>
            <end position="302"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="423"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="477"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="479"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD40801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="495" mass="52430" checksum="D7F6C5739763D30D" modified="2010-04-20" version="1">MGASVGIPLGLTFDDVLLLPGESDVVPSDVDTSTKLTRNITLRMPLLSAAMDTVTEARMAIAMARQGGLGVIHRNLSAEHQAQQVDLVKRSESGMVADPVTCAPYQTLAEVDALCARYRISGVPVVDESGKLVGIVTNRDMRFETDMTVRVSDVMTTESLITAKVGVSTEAALDLLKRNKVEKLPIVDDDGQLRGLITVKDFTKREQYPHATKDDSGRLRVAAAVGVGEEQYARAGQLVDAGVDALVVDSSHGHSRGVLEMITRISKDFGDRIDIIGGNIATFEGATALIEAGSDAVKVGVGPGAICTTRVVSGVGAPQISSIMDAARAAKPHGVPVIGDGGIQYSGDISKAIVAGADCIMLGQLFAGCDESPGELVFINGKQFKSYRGMGSLGAMQSRGDSKSYSKDRYFQQDSKDDKLVPEGVEGQVPYRGSLAQVMHQLVGGLRIAMGYAGAGTIDALHERGRLVRITAAGLKESHPHDIQMTVEAPNYHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAB2</accession>
    <name>D3QAB2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3024"/>
    <dbReference type="EnsemblBacteria" id="ADD42695">
        <property type="protein sequence ID" value="ADD42695"/>
        <property type="gene ID" value="Snas_3024"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3024"/>
    <dbReference type="eggNOG" id="COG4993">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1531626_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="175" mass="19320" checksum="1FEC1D2FE6597867" modified="2010-04-20" version="1">MPPQPRELKLALILAGLAVLIHFVGRAWHTALLAANLGDNTRPEQTEQLLTSALSPLIYGAIVVLLGWFLWRGYRVGLWLFVIGTGLAALRVLSFVWWLVIGLIRDGSAESMLRYVDTPGPLGENIAAVFAVPVLLLLIRPAVWRWSRKADAIRTVTGLVKRGAPIRQLPPAIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAH9</accession>
    <name>D3QAH9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018333.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3091"/>
    <dbReference type="EnsemblBacteria" id="ADD42762">
        <property type="protein sequence ID" value="ADD42762"/>
        <property type="gene ID" value="Snas_3091"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3091"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_645029_0_0_11"/>
    <dbReference type="OMA" id="WPTTPVI"/>
    <dbReference type="OrthoDB" id="520970at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="467" mass="51135" checksum="1AA380F5380569B2" modified="2010-04-20" version="1">MKRFPRLTTTERLQVTLLNTLPAFARGIAIARPKTVSLLNRLQVDRRMVDLFDRLRERYRGLPVWISSVNGPTLLLLSPRHVERVLGGSDQLYTPDTKDKHRALGVFQPHGVIVSRGELRVKRRQFNEAILDTSQPAHAERYARIVAAEIDAMMTGPGRDGTLIWPEIKRAFDCVARRVVLGDGAREDVDSTRLLAKLRREANSLGAKPGTRRRVAAWKADWDNRLARYAESAPADSLIGRVTDTYAETEVRPLGQVTQWLTALDMVPVLAARTLALLASHPEHFARANEELAAADAHHGASTAASIAAQPYLQACVMEAARLWPAVPNLARATTRPLDWDGVILKTGTTMVIPALYHARSRRQGRFAHRFTPERWLDGGLDRDWTIMPFSLGPARCAGAMLGGLLATAGCAALLRQAYVRLNTPRLAPDKPLPMAMPVTDISLAVGAKPVTPAPVATASGASASGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAJ2</accession>
    <name>D3QAJ2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018346.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3104"/>
    <dbReference type="EnsemblBacteria" id="ADD42775">
        <property type="protein sequence ID" value="ADD42775"/>
        <property type="gene ID" value="Snas_3104"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3104"/>
    <dbReference type="eggNOG" id="COG3333">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022936_2_0_11"/>
    <dbReference type="OMA" id="QQPDIVW"/>
    <dbReference type="OrthoDB" id="735109at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002823">
        <property type="entry name" value="DUF112_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01970">
        <property type="entry name" value="TctA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="426"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="520" mass="55020" checksum="D22737FE1ECF85D7" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB02</accession>
    <name>D3QB02_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1109</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1109"/>
    <dbReference type="EnsemblBacteria" id="ADD40819">
        <property type="protein sequence ID" value="ADD40819"/>
        <property type="gene ID" value="Snas_1109"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1109"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_425603_0_0_11"/>
    <dbReference type="OMA" id="GHRWWRV"/>
    <dbReference type="OrthoDB" id="764475at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="475"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="503"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="693" mass="74143" checksum="0E7E79FBA828AC74" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB97</accession>
    <name>D3QB97_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplO</name>
        <name evidence="10" type="ordered locus">Snas_1204</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016485.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1204"/>
    <dbReference type="EnsemblBacteria" id="ADD40914">
        <property type="protein sequence ID" value="ADD40914"/>
        <property type="gene ID" value="Snas_1204"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1204"/>
    <dbReference type="eggNOG" id="COG0200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055188_4_1_11"/>
    <dbReference type="OMA" id="FKNINRV"/>
    <dbReference type="OrthoDB" id="1874945at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_L15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="9">
        <location>
            <begin position="28"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD40914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="151" mass="15801" checksum="EC9D97A93943FC7C" modified="2010-04-20" version="1">MTIKIHHLRPAPGSNTAKTRVGRGEGSKGKTAGRGTKGTKARKNVPAFLEGGGVPLHMRLPKLKGFKNRFKVTYQVVNLDKLAELFPQGGTVGPDELAKAGAVRKGQPVKVLGSGDLTGIKLDITAHAFSKTAKDEILAAGGNAVVLGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBF6</accession>
    <name>D3QBF6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DEAD/DEAH box helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3167</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018409.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3167"/>
    <dbReference type="EnsemblBacteria" id="ADD42838">
        <property type="protein sequence ID" value="ADD42838"/>
        <property type="gene ID" value="Snas_3167"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3167"/>
    <dbReference type="eggNOG" id="COG4581">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002902_4_1_11"/>
    <dbReference type="OMA" id="ECHYMND"/>
    <dbReference type="OrthoDB" id="66530at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="56"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="286"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="919" mass="100494" checksum="4C528B9DF38820FE" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBG3</accession>
    <name>D3QBG3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_3174</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018416.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3174"/>
    <dbReference type="EnsemblBacteria" id="ADD42845">
        <property type="protein sequence ID" value="ADD42845"/>
        <property type="gene ID" value="Snas_3174"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3174"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_3_5_11"/>
    <dbReference type="OMA" id="RDVKLNQ"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="9"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="124"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="230"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="383" mass="40577" checksum="39E12DC1AD711BD4" modified="2010-04-20" version="1">MTVQRFFPSDEARAIVELARDIAEGELAPRVNEFEARGEFPREVLRKLGAAGFLGLPYPERYGGGGQPYEVYLQVLEELAYRWVVVAEAVSVHTLACFPVAEFGTDAQRERWLPQMVGGDTLGAYCLTEPSGGSDAASLSTKAVRDGDGFVVEGTKAFITHAGVADFHSVFARTGGPGARGVSCLVLPEGTPGVVPQRLEHKMGLSASPTAQIVFDGARVGSDCLVGEEGRGFSIAMAALNAGRLGIAACAVGLAQAACDYATQYARGRRQFGSPVIDFQGVGFMLADMATQISAARALVSHAARLRDAGRGFRVAAAQAKLFATDVAMRVTTDAVQVLGGYGYVSDHPVERYFREAKVLQIVEGTNQIQRLVISRALAQGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBK7</accession>
    <name>D3QBK7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018460.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3219"/>
    <dbReference type="EnsemblBacteria" id="ADD42889">
        <property type="protein sequence ID" value="ADD42889"/>
        <property type="gene ID" value="Snas_3219"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3219"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_2_11"/>
    <dbReference type="OMA" id="AVLCHYG"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="180" mass="19691" checksum="48F4D6E895C4848F" modified="2010-04-20" version="1">MLKGSKVGLRARHDDDIAILRTELYDDVVNASRAEGPPWRPITPGSNDKRLVVDDSAQGLVQFSVVDVDSDALVGTATLWGIDPHHRSAHIGLGLLPSCRGKGYGTDVVAVLCYYGFTVRGLHRLQIETLADNVGMLRSAERNGFVREGVRRASTWVLGEFLDEVVMGLLAHEWKPDADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBY5</accession>
    <name>D3QBY5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020445.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5240"/>
    <dbReference type="EnsemblBacteria" id="ADD44874">
        <property type="protein sequence ID" value="ADD44874"/>
        <property type="gene ID" value="Snas_5240"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5240"/>
    <dbReference type="eggNOG" id="ENOG5032R1X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072323_0_0_11"/>
    <dbReference type="OMA" id="AHALGYW"/>
    <dbReference type="OrthoDB" id="343485at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025337">
        <property type="entry name" value="Questin_oxidase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14027">
        <property type="entry name" value="Questin_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="407" mass="44668" checksum="EDA34B95125E8A00" modified="2010-04-20" version="1">MTDETQRQQNPDEARRQQQNSEETQRRQDPEKTQRQQDPDAAQRQVPDEGLRQQNSDAAQRQQILDEALLRLHTTGPEFDDWLSNHAPMAVEALAHHGHADRVHHWIDEYEHVLEEAPRPSDPITVENWREALGDPRRLGDWPSWFDNELAEAEWTEVLARWWPRLLPGIVASATHGVIRVGHAVRTLREQGPNEARLAELARAFGYWAARWQPMVRPTAPSGGLDAASALARVPRIPEQDGGIRDRLAQLDGLAGWESAQAALRLPGEAEAVPDAVRAIVTAAVNRYLSHGHGSAVMLVHAATAPNAVLRVLPSLPREHWHDSAAFAWSASAAVMSIYAPAEAAPTTELPQAPDGSGAEEEIFDAAAANGDAHVIKFADTALDVRSWTGDATPLAAALRSAQLIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC19</accession>
    <name>D3QC19_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5274</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020479.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5274"/>
    <dbReference type="EnsemblBacteria" id="ADD44908">
        <property type="protein sequence ID" value="ADD44908"/>
        <property type="gene ID" value="Snas_5274"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5274"/>
    <dbReference type="eggNOG" id="COG3023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037559_0_1_11"/>
    <dbReference type="OrthoDB" id="1584918at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015510">
        <property type="entry name" value="PGRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11022">
        <property type="entry name" value="PTHR11022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049046" evidence="1">
        <location>
            <begin position="34"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="2">
        <location>
            <begin position="53"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="224" mass="24287" checksum="0BFF84367057C63B" modified="2010-04-20" version="1">MPEFKLSRRGVLGGLAGLAAVSSVPLVAGTAFAAKRDVPQPDIYSCADWGARPPNGTPTVVSKRPNKIICHHTAYPNTEDLSLEYAFANSRDIQDLHMDNNGWIDSGQHFTNSRGGFLTEGRHGSLDALLDGTYMIQGAHCVGQNSQAIGIENDGSYHTGEQPTEPQWASLIDFCAFICFKYRIPATEIYGHKDFNSTLCPGGIHERLPELREAVQGVLDGSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU03</accession>
    <name>D3PU03_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phenylacetate-CoA oxygenase, PaaH subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016520.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1239"/>
    <dbReference type="EnsemblBacteria" id="ADD40949">
        <property type="protein sequence ID" value="ADD40949"/>
        <property type="gene ID" value="Snas_1239"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1239"/>
    <dbReference type="eggNOG" id="COG3460">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141459_2_0_11"/>
    <dbReference type="OMA" id="PYRHPTF"/>
    <dbReference type="OrthoDB" id="2083684at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009359">
        <property type="entry name" value="PaaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038693">
        <property type="entry name" value="PaaB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06243">
        <property type="entry name" value="PaaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF030200">
        <property type="entry name" value="PaaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02157">
        <property type="entry name" value="PA_CoA_Oxy2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="93" mass="10477" checksum="8D400F2B8A21FA74" modified="2010-04-20" version="1">MSDNPLWEVFVRPRRGLSHGHVGSLHAPDADMALRNARELYTRREEGVSIWVVPSSAITASSPEEKDAFFAPAADKIYRHPTFYEMPEGAEHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU89</accession>
    <name>D3PU89_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1326"/>
    <dbReference type="EnsemblBacteria" id="ADD41035">
        <property type="protein sequence ID" value="ADD41035"/>
        <property type="gene ID" value="Snas_1326"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1326"/>
    <dbReference type="eggNOG" id="COG0859">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_700023_0_0_11"/>
    <dbReference type="OMA" id="FEGWRIR"/>
    <dbReference type="OrthoDB" id="1499813at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="394" mass="42348" checksum="BEAE6B86C8BD99E1" modified="2010-04-20" version="1">MSFEGWRIRPVATWRGGPPRLPHDQLPIGRTLPYRRAAGAGPSGPTELYTHVIECGWRAEFLVRSKIPAGPPTEPARLGDLLLSMATVRALTEAFPDERPVYRGDRGALMSRCELDLDIGETADGSTVSTDGGAVQRLEVRPVRPPRWVGWPEAPDRMTTVMPIWLDDTGNGVDVHAAMPSRYYLQIEQDLGIRLPADAGPVAPRYRSTVGSAEPGHTVFVATTSSPDGKDFGIDGFAAVARELAALSPRASRFTLLSNELDNGTRVGDGGLIEIVNGMDAAECVDLFASAELVVGNDTGLTHLAALSLRPDGTGPEVISLYNIFSPLAWTTASPRHHAVATRLSQQFALSDVNIYLNQSGEFVDPAAWADAGSMRTVPAEVVARFAAECAGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUA3</accession>
    <name>D3PUA3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular small neutral protease</fullName>
            <ecNumber evidence="3">3.4.24.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Snapalysin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1341</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes proteins with a preference for Tyr or Phe in the P1' position. Has no action on amino-acid p-nitroanilides.</text>
            <dbReference type="EC" id="3.4.24.77"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M7 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.77" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1341"/>
    <dbReference type="EnsemblBacteria" id="ADD41049">
        <property type="protein sequence ID" value="ADD41049"/>
        <property type="gene ID" value="Snas_1341"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1341"/>
    <dbReference type="eggNOG" id="COG5640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124996_0_0_11"/>
    <dbReference type="OMA" id="GCATIYI"/>
    <dbReference type="OrthoDB" id="1649119at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000013">
        <property type="entry name" value="Peptidase_M7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02031">
        <property type="entry name" value="Peptidase_M7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00787">
        <property type="entry name" value="NEUTRALPTASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048355" description="Extracellular small neutral protease" evidence="6">
        <location>
            <begin position="35"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="189" mass="20008" checksum="571E05ED891089CE" modified="2010-04-20" version="1">MPIMSRIRKTLVVFTAFAIAMLGFQFFTASPAAADADVQARTVYYTAYAYSSQSAQAAQIWNSRVPNLNMVSRSNGTIRIYATTGGGSRAYPCGLGCATIYIDSRDIAAGHNTLRIISHEIGHGHRLPDTYNGICSYLMSGGSAGTSCTNPYPNSGEASRVNSYYAGFALKGPAPVSGGVYAPTYPSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUA4</accession>
    <name>D3PUA4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DSBA oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1342</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1342"/>
    <dbReference type="EnsemblBacteria" id="ADD41050">
        <property type="protein sequence ID" value="ADD41050"/>
        <property type="gene ID" value="Snas_1342"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1342"/>
    <dbReference type="eggNOG" id="COG1651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_47_3_11"/>
    <dbReference type="OMA" id="GTHDSWV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="3">
        <location>
            <begin position="90"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="246" mass="26407" checksum="0F31C42854C3184C" modified="2010-04-20" version="1">MTNPPPPGDPNQWGTPPPPMPPPVPVPAPAKNQHMWLYVVFGTVAALLIAGGVWVGVVLIGESRDKDDKSTAAEPQAEVADGGIVVGDGEPTVDIYLDFGCPACKKFQETNDSALESAIEDKKATIRFHPLNFLKSMFTDEYPGRAASASVCAADEDKFYDYYQVLMDNQPPEGGAGLDDDKLVELGADVGLGEKFADCVGEGSYRDWVDRETDKASDIAATPTVFIDGDEVQSEDFAAEFDKKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUR0</accession>
    <name>D3PUR0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gluconate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020505.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5300"/>
    <dbReference type="EnsemblBacteria" id="ADD44934">
        <property type="protein sequence ID" value="ADD44934"/>
        <property type="gene ID" value="Snas_5300"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5300"/>
    <dbReference type="eggNOG" id="COG2610">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027949_0_2_11"/>
    <dbReference type="OMA" id="MVLPKGH"/>
    <dbReference type="OrthoDB" id="1585405at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015128">
        <property type="term" value="F:gluconate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003474">
        <property type="entry name" value="Glcn_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30354">
        <property type="entry name" value="PTHR30354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02447">
        <property type="entry name" value="GntP_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002746">
        <property type="entry name" value="Gluconate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00791">
        <property type="entry name" value="gntP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="436"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="461" mass="47659" checksum="E77FC845986AA692" modified="2010-04-20" version="1">MPEDWSQTLTTGPLLAIAAAAIAVLLFLIIKLKLHAFPALVLVSLGTAFAAQVPPAAIVATLTDGFGTTLASVALLVGLGAMLGRLIEVSGGARTMAEALVRRFGERRAPFALGVASLLFGFPIFFDAGLVVMLPVVFSIARRLGGSVLTYGLPAAGAFSVMHVFLPPHPGPVAAGELMHADIGLVVLFGLVIALPTWYLAGYLYGRFMGRRFELPVPKLLGGTDDEDTTDVKLPRVGPVVSILLLPLVLIFVNTGLDLATSAKWVSEDATWVQVAMAIGSTPVALLITVLVASYVLGTRLGRDRSALEKTLESALGPVCSVILITGAGGMFGAVLRASGIGDALADELNALGLPVILAGFVVATALRIAQGSATVALITAAGLIQPAVEAGAFNGVQLAAIVLGLAAGSVMTSHVNDSGFWLVGRLMDMDVKTTLKTWTVMETLIGVIGFGMAWAIFVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV57</accession>
    <name>D3PV57_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mycothiol-dependent formaldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1403</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016681.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1403"/>
    <dbReference type="EnsemblBacteria" id="ADD41110">
        <property type="protein sequence ID" value="ADD41110"/>
        <property type="gene ID" value="Snas_1403"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1403"/>
    <dbReference type="eggNOG" id="COG1062">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_14_1_11"/>
    <dbReference type="OMA" id="IHHYMGT"/>
    <dbReference type="OrthoDB" id="1859760at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017816">
        <property type="entry name" value="MycoS_dep_FDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03451">
        <property type="entry name" value="mycoS_dep_FDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="17"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="361" mass="37801" checksum="7229B9BAE669E61A" modified="2010-04-20" version="1">MSQQVRGVIAAAKNAEVSIETIVVPDPGPGEALVRVRACGVCHTDVHYRDGGINDEYPFLLGHEASGVVEAVGPDVTDVAPGDFVILNWRAVCGDCRACRRGRSQYCFNTHNATQKMTLVDGTELSPALGIGAFAEKTLVAAGQCTKVDPEASPAVAGLLGCGVMAGIGAAVNTGNVGRGDSVAVIGCGGVGSAAVAGSRLAGASRIIAIDVDRRKLDWAKQLGATHTVDAYGVDVVEAVRELTDGNGADVVIEAVGRPETYEQAFYARDLAGTVVLVGVPTPDMRLELPLLDVFARGGALKSSWYGDCLPSRDFPMLIDLYRQGRLDLDVFVSETIGLDDVEAAFTRMGRGEVLRSVVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVF3</accession>
    <name>D3PVF3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018638.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3403"/>
    <dbReference type="EnsemblBacteria" id="ADD43067">
        <property type="protein sequence ID" value="ADD43067"/>
        <property type="gene ID" value="Snas_3403"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3403"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_11"/>
    <dbReference type="OMA" id="IHARADQ"/>
    <dbReference type="OrthoDB" id="1752728at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="31444" checksum="80A47729FC7C397E" modified="2010-04-20" version="1">MKALTAVGYGPLADLTFSDVDKPVPGPGQVLVRTEAVALNPLDVKLVLGSVREVFPVTHPFVVGIDVSGTVEAVGPDTIGYAPGDAVTAMNLGVAGAVAEYTLAQTGPLLTHRPEGVDARSAAALPAAGLTALSLLHHCVPVAGRDVLISGATGGVGSFAVQLFAAAGARVLATGRPDDTETVLGWGAHHVIDYTGGKTAQLARELVPGGVDVVLALAEDGAALPGIAAAAIDEGLVLTCTEQPTALERGVTVERVDLTARDGDLSGLAARVSLGELRVPVTGVYPFSEARTAYEDLVGKHTVGKLVVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVQ7</accession>
    <name>D3PVQ7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3508</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018742.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3508"/>
    <dbReference type="EnsemblBacteria" id="ADD43171">
        <property type="protein sequence ID" value="ADD43171"/>
        <property type="gene ID" value="Snas_3508"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3508"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_7_4_11"/>
    <dbReference type="OMA" id="DPYYFNY"/>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048623" evidence="2">
        <location>
            <begin position="34"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="3">
        <location>
            <begin position="78"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="361"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="508" mass="54189" checksum="BA18CA68BA65E839" modified="2010-04-20" version="1">MSPASRFGRRLTAVIGALATLSLLLAGCSGSQAEPGKLVIGVTTDANALFPWKATQFQSIAVLQNLYGTLTEFDKDLKVVPGLAESWDTSKDGRTLTFHLRSGVTFADGSAFDSADVKDSLDKIRDPKTAAVAASTLASVKKVTAPDADTVTLKLSGPDAALPSNLASVNTAMLSSDDTEKQLAAKPNGTGPFAFDSRKPSQTLKLKKNDAYWGEAPKLDSVEFRVIPDDDSILAAMQAGNVQFAVFDNPVVGQTAEDLGLNVAKTSQLSYHALQLNAKRDVLSDVNTRLAVQCAIDRSAVLDTAGFGEGKVTGPITSPDYLSDPDDRPCPTRDLDKSAEYLRKAGKDSLTLKTIVSQGEYATSVDEAQNLKSQLADANIELDLEVLESGAFVDAWVGADFDAAVALNGGREDPDGMYGRYFTSTGNLNKVAGYSSPTLDKLFAEGRSTSDLAKREEIYTKVGRELEDNAAWIWLFSGFTYTATTANVHGFTPLESGSLQYLRTTSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVT9</accession>
    <name>D3PVT9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5428</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020631.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5428"/>
    <dbReference type="EnsemblBacteria" id="ADD45060">
        <property type="protein sequence ID" value="ADD45060"/>
        <property type="gene ID" value="Snas_5428"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5428"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037105_0_0_11"/>
    <dbReference type="OMA" id="TRWFEPA"/>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="3">
        <location>
            <begin position="219"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="349" mass="36462" checksum="A28E806004D1E0F0" modified="2010-04-20" version="1">MSESHPLTLKIGLAIAAVMVLPLVAVVALAIVAVSTDDAAESGGVTCSITKKTATALGLSKTQLGHAATIYEVALDKSMGRRAAIIGIATAIQESTLHNYGHLGDRNDHDSLGLFQQRPSAGWGSPTQITNPKYAAGKFFDSLKKVSGWQSLPLTVAAQTVQGSAFPDAYAKHEPKAKKIVNTLENPRICAAGTGSGKWAKPVNAGIVSGYRTSERPDHHGIDFGAARGTTIKAVGAGTVKTVTCNASTGAGQPYSCNIDGGVHIMGCGWYVEIQHADKTVTRYCHMVSRPSVNEGQKVNAGQKLGKVGNSGNSSGPHLHFEAHGDYPADPGNAIDPRKYLKDRGISVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVV0</accession>
    <name>D3PVV0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5439"/>
    <dbReference type="EnsemblBacteria" id="ADD45071">
        <property type="protein sequence ID" value="ADD45071"/>
        <property type="gene ID" value="Snas_5439"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5439"/>
    <dbReference type="HOGENOM" id="CLU_2540950_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="83" mass="9561" checksum="5F7E5A88CD40BC5D" modified="2010-04-20" version="1">MTTPPTAATTPLTMTNHTMTTAYQQGQVTPLSPVITEFVYFNGDWWTIDPPDAWIRITDDTFAKFLDQQYYKMKSTIDLSVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVX3</accession>
    <name>D3PVX3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5462</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5462"/>
    <dbReference type="EnsemblBacteria" id="ADD45094">
        <property type="protein sequence ID" value="ADD45094"/>
        <property type="gene ID" value="Snas_5462"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5462"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="GMFGPVM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="31"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="491" mass="50608" checksum="8144B685E858D36C" modified="2010-04-20" version="1">MTVIEAPERPQTLTEPATAAEPAPYRWRWAALSVIMAGSAMELLDSSVTSVAGPTMQRDLGGGAGLIQWLTAAYTLAMVGGLLIGARLGDIFGRRRMFLLGAVGFTITSLAVAVSVSPETAIAARVAQGLFGAAMVPQVFALIKSMFPASESQKAFGMAGPIMGAAVIGGPSLAGWLIGLDLFDTGWRMVFGINLPIGIAIVVLAAKLLPKDSGDAKAKLDIIGAGLASAASALLIYPLVQGREAGWPAWSFAMIAVSLILFGAFGLYQVRRAANGKDVLVIPSLFRKRAFNGGLVLGVLLMAAMAGVGLVMGLHLQLGLHFSPLAAAAAMIPFAVAMGGTMGFGDKLARFGRKTLLAGALLKASGVTILLVTLEQAGADLVWYQLIPGLMLSGIGAAMFMGRYFDSVMQGVEPQEIGSASGTLTSVQQLGASFGVAVLGTAFFGRFAGDLESLMDASRIALGLTVVVLVIGFAVGFTLPKQAATNSQPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWE9</accession>
    <name>D3PWE9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1603</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016877.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1603"/>
    <dbReference type="EnsemblBacteria" id="ADD41306">
        <property type="protein sequence ID" value="ADD41306"/>
        <property type="gene ID" value="Snas_1603"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1603"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_11"/>
    <dbReference type="OMA" id="PVAHHVC"/>
    <dbReference type="OrthoDB" id="293754at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:cellular aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="6">
        <location>
            <begin position="15"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="499" mass="53349" checksum="8654BA374095C439" modified="2010-04-20" version="1">MSTAAPQISDGYLISTHPGNGSEVGRFAVDDAESVAKAVARARDAQTWWANLGFTQRRKLLLECRAEMARRIKDLVRLIRAETGKSVNDAFTEVAGCFENLAWAPKNARRVLGPRRRRGSLSMIDHSAYVEYRPYGVVAVIGPWNYPMYTVMGSVVYALAAGNTVVLKPSEYTPAVGQWLADVIDEVVGRPIVTVVHGLGETGAALCESEVDKIAFTGSVPTARKVAMAAAKRLIPVLIEGGGKDAAIVDVDADLDKTAEQLLWGAFTNAGQTCIGYERAYVPESIATELIDKLVKQATGIKVGDGEDAQIGPITMPRQIDVIAAHIDDALNRGATAVVGGREAVQPPYVHPTILVDVPEDSRAVTEETFGPVLVVNTVADAEEGLRRANATEYGLGGAVFGKRNAMSLARRMRSGMTSINSGFAFAGLPSLPFGGVGSSGYGRAHGDDGLREFAVVKSIAKRRAPGVIPVFSLNRKASHNKLIERIITFGSGKPRPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWN7</accession>
    <name>D3PWN7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3599"/>
    <dbReference type="EnsemblBacteria" id="ADD43259">
        <property type="protein sequence ID" value="ADD43259"/>
        <property type="gene ID" value="Snas_3599"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3599"/>
    <dbReference type="eggNOG" id="COG2319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_395817_0_0_11"/>
    <dbReference type="OMA" id="VEHISEP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="647" mass="71782" checksum="1A07C9D031E2F032" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX24</accession>
    <name>D3PX24_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020819.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5618"/>
    <dbReference type="EnsemblBacteria" id="ADD45248">
        <property type="protein sequence ID" value="ADD45248"/>
        <property type="gene ID" value="Snas_5618"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5618"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_13_0_11"/>
    <dbReference type="OMA" id="GWTLYDW"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="456" mass="48892" checksum="924D255E34ECF607" modified="2010-04-20" version="1">MSNDFIAQAQERLDTLRAKHRIPGASLAILVDGQIHELASGVLNRDTGVEVTPDSLFQSGSVAKIYTATVIMRLVGEGKLDLDAKVVDVLPEFSTPDPEAAAQITIRQLLSHTGGVTNDFHGAADATGGDALARYVEAAREVPLDLPPGTAASYGSLGIVVLGRVIEVLTGTTWNQALKDLLFDPLGLKRSVTLPEEAMRYRYAWGHLGQPGTDPEPIDMFSYIPRAFAPAAQVLVSAGDLVRLAKLHLDGGVAPDGTRIVAAEAVAAMQRVESTPVDRWSVSADHWGLGWCLYDQPGFQGFGHDGSAVSQHAMLRVFPEQGVALALMTNSGNGRSLYAELFPELLDALGITMPAPFGPADPPITVDATRFYGLYQRAGVDITISERDGKPYAKYEFVDVSAEIPPLEGEMRPVSDTVFSVFMSGEGINEEMPVIFTTHNGTEYCWAGMRAAPKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXH5</accession>
    <name>D3PXH5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1740</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017009.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1740"/>
    <dbReference type="EnsemblBacteria" id="ADD41438">
        <property type="protein sequence ID" value="ADD41438"/>
        <property type="gene ID" value="Snas_1740"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1740"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="ARICAAQ"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="152"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="228" mass="24631" checksum="99FBD9E51EE3B4E2" modified="2010-04-20" version="1">MTEPISVLVVDDQSLLRGSFTLLIDTEDDLRVVGEAGTGVEAVDAARRLLPDVVLMDVRMPDMNGIEATRRICGDPALSGVRVLMLTTFDLDEYVYSSLRAGASGFLLKDVPPTQLLHAIRVVANGESLLAPSVTRRLVAEFVARPHESTVASTDLAAVTEREREVLTLVARGLSNTEIAERLHLSLATVKTHIGHLLRKLTARDRAQLVIAAYESGLVTASAPRGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXN4</accession>
    <name>D3PXN4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018935.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3707"/>
    <dbReference type="EnsemblBacteria" id="ADD43364">
        <property type="protein sequence ID" value="ADD43364"/>
        <property type="gene ID" value="Snas_3707"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3707"/>
    <dbReference type="eggNOG" id="COG0790">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012157_0_0_11"/>
    <dbReference type="OMA" id="GNTDVLC"/>
    <dbReference type="OrthoDB" id="402503at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="994"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1020"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1020" mass="111874" checksum="C34014B99B1E5E2A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXQ3</accession>
    <name>D3PXQ3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3726</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018954.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3726"/>
    <dbReference type="EnsemblBacteria" id="ADD43383">
        <property type="protein sequence ID" value="ADD43383"/>
        <property type="gene ID" value="Snas_3726"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3726"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_316785_0_0_11"/>
    <dbReference type="OMA" id="THIRASM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="756"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="826" mass="84878" checksum="A3C492E1EE102E97" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXW0</accession>
    <name>D3PXW0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5659</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020860.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5659"/>
    <dbReference type="EnsemblBacteria" id="ADD45289">
        <property type="protein sequence ID" value="ADD45289"/>
        <property type="gene ID" value="Snas_5659"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5659"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064446_0_0_11"/>
    <dbReference type="OMA" id="CATIVQV"/>
    <dbReference type="OrthoDB" id="1547278at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="237" mass="24744" checksum="FF039AC4331A0711" modified="2010-04-20" version="1">MNDSLVAPVEESTTATSGLWLVEDTQTLIDAIESGSWVDGTIGGITVGLDALSVAMDPLGALASMAIGWLIEHVKPLRDALEEVTGDADKVNSYAKTWENVSTKLLDAGTKLQTAAHKDLETWQSPAANAYSIHADYTTNAVGGIGALAEVMSAATAGAGMLVATTRAIVRDLIADCVATLLVRIPEWLAEVGLTLGLGTPWVISQAASLIAKWVGRITNYLNSLVSSISNLQALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY26</accession>
    <name>D3PY26_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Agmatinase</fullName>
            <ecNumber evidence="6">3.5.3.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5725</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.11" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020926.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5725"/>
    <dbReference type="EnsemblBacteria" id="ADD45355">
        <property type="protein sequence ID" value="ADD45355"/>
        <property type="gene ID" value="Snas_5725"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5725"/>
    <dbReference type="eggNOG" id="COG0010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_0_2_11"/>
    <dbReference type="OMA" id="GAYDHED"/>
    <dbReference type="OrthoDB" id="1598732at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008783">
        <property type="term" value="F:agmatinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005925">
        <property type="entry name" value="Agmatinase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01230">
        <property type="entry name" value="agmatinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="346" mass="37750" checksum="43EA9970F2F12725" modified="2010-04-20" version="1">MTPENQLPPGLRAQLDSSSYMGVPTFGLRPHLSEPEQLDAWRPDVAIIGAPWDDNTTNRPGARFGPRALRANAYDPGSYHLDLEIEIFDHLDVVDYGDAIVSPGLWEPSKTAIHQRVSEVTTRDIIPVIIGGDHSITWPAALAVGAHHGHGRIGMIHFDAHADTADIVRGNLASHGTPMRRLIESGAITGKHFIQVGLRGYWPPPDVQAWMRAQGMRHHTMQEIWERGIQSVMDDVITEALDGTDGIYISIDIDVLDPGFAPGTGTPEPGGLTPADLLRAVRRIAMDTNVVALDITEVCPPYDHADLTTNNAHRLIWETLAGLAHRRRQTDAAANPPDPSTDAPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYA9</accession>
    <name>D3PYA9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1779</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017047.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1779"/>
    <dbReference type="EnsemblBacteria" id="ADD41476">
        <property type="protein sequence ID" value="ADD41476"/>
        <property type="gene ID" value="Snas_1779"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1779"/>
    <dbReference type="eggNOG" id="COG2345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087580_2_1_11"/>
    <dbReference type="OMA" id="PANVSHH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="2">
        <location>
            <begin position="25"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="23182" checksum="824CF731C807A2B7" modified="2010-04-20" version="1">MTEDSSTPSAEHPENWPQRQLRDATSLRALAHPLRLRLLELLGVHGPATATELAERVGHSPANCSWHLRQLAAGGFIEEAEGGTGRQRIWRFVPSGSSYGYSDDAPEVAEAAATASAIQLEHEVDELRTWRATRHTDSDRWRDVAFTTQSILWLTADELEELSEQVAELYLRQVRRHFEPETRPTGSRPVRLIAWGIPAKNLETEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYM1</accession>
    <name>D3PYM1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH-dependent FMN reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3798"/>
    <dbReference type="EnsemblBacteria" id="ADD43454">
        <property type="protein sequence ID" value="ADD43454"/>
        <property type="gene ID" value="Snas_3798"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3798"/>
    <dbReference type="eggNOG" id="COG0431">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055322_4_1_11"/>
    <dbReference type="OMA" id="PYFAADV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="8"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="202" mass="21785" checksum="D5E84C1DFAF1FB5F" modified="2010-04-20" version="1">MSPTTTGPRILVFSGSARTGSHNARLAELARRALAAAGARPHPVNLREFALPLYDGDIQAAQGIPDAAHRFADLLREHDGVVIVSPEYNYSMPGTVKNLIDWVSRIKPWPTIGVNGLLMSASPSAVGGHRGLIALRVPLEGIGARLHPEMFTLAFADKAYGDDGELADAGSRDRLRRLVSDFLDVVAATIHYRQSRELVTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYS2</accession>
    <name>D3PYS2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 15">NAD(P) transhydrogenase subunit beta</fullName>
            <ecNumber evidence="6 15">7.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Nicotinamide nucleotide transhydrogenase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ordered locus">Snas_3849</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 15">The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the PNT beta subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="6 15"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019076.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3849"/>
    <dbReference type="EnsemblBacteria" id="ADD43505">
        <property type="protein sequence ID" value="ADD43505"/>
        <property type="gene ID" value="Snas_3849"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3849"/>
    <dbReference type="eggNOG" id="COG1282">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007866_4_0_11"/>
    <dbReference type="OMA" id="KRGMSAG"/>
    <dbReference type="OrthoDB" id="788546at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:NAD(P)+ transhydrogenase (AB-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012136">
        <property type="entry name" value="NADH_DH_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034300">
        <property type="entry name" value="PNTB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02233">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000204">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8 15" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14 15 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0520">NAD</keyword>
    <keyword evidence="11 15" id="KW-0521">NADP</keyword>
    <keyword evidence="18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 15" id="KW-1278">Translocase</keyword>
    <keyword evidence="10 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="PNTB" evidence="17">
        <location>
            <begin position="11"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ADD43505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="466" mass="47480" checksum="794E6E936CE1DEFA" modified="2010-04-20" version="1">MTTTETVIRYLFLAAAACFVIGLHLMNSPKTARRGNLLSAAAMAVGIGATAVLLIAEGAITTTGWLVLLAGAAVGSAAGLYLARSVEMTAMPQLVSLFNAVGGGAAALLAVEHLLQAETVHVRETIPGGLDILIGAVTFSGSVVAAGKLQGLIPGRPIVFLGARALNVVLGLVFVGSTAWLVLDEGNLVAMLLLLVAATVFGVTMVLPIGGADMPVVISLLNAFTGTAVAMAGFVLGEVVLIVAGALVGASGAILTKLMADAMNRSITNIILGGFGTGDEAATADDSGGTVRSVSADDVAIQLAYAQKVVVVPGYGLAAAQAQHELASLAEILEGHGVEVSYAIHPVAGRMPGHMNVLLAEAQVPYPALREMDEINPDFPQVDVALVIGANDVTNPIARKPGNPMSGMPILDVDKARSIVVVKRSMGHGYAGIDNTLYSDPKTGMFFTDAKKGMVALAAAVRSFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYY9</accession>
    <name>D3PYY9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5788</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5788"/>
    <dbReference type="EnsemblBacteria" id="ADD45418">
        <property type="protein sequence ID" value="ADD45418"/>
        <property type="gene ID" value="Snas_5788"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5788"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="RERAPEC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="214" mass="23019" checksum="1C37314FD1D1296D" modified="2010-04-20" version="1">MDDTPVRVLIVDDQTLMRQGLRKLLEIEPGVTVSGAAASGQEALALLATTTVDVALVDAKMPGMDGVALIRRLAAEHPSVACVILTTFDDDEYIFGGLAAGARGFLLKDTPPDELVTTLRRAAAGETVLGSPAAERVVARLRTDPHGTGLEALSAREREVGDLIAQGAHNREIARRLFITEGTVKNHVTALLRKLGMRDRTQLALFLAKHRDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ80</accession>
    <name>D3PZ80_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5881</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CsoR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021080.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5881"/>
    <dbReference type="EnsemblBacteria" id="ADD45509">
        <property type="protein sequence ID" value="ADD45509"/>
        <property type="gene ID" value="Snas_5881"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5881"/>
    <dbReference type="eggNOG" id="COG1937">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130332_0_1_11"/>
    <dbReference type="OMA" id="TYCDDVL"/>
    <dbReference type="OrthoDB" id="1868412at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003735">
        <property type="entry name" value="Metal_Tscrpt_repr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038390">
        <property type="entry name" value="Metal_Tscrpt_repr_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33677">
        <property type="entry name" value="PTHR33677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02583">
        <property type="entry name" value="Trns_repr_metal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="98" mass="10873" checksum="99E70BF5A3646BDB" modified="2010-04-20" version="1">MDEKTEYWYSTDRDALLKRLRRVEGQVRGIQRMVDEDEYCIDILTQISAANKALRAVALHLLEGHLGHCVADATAAGGETAEAKVKEATEAIGRLMKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ87</accession>
    <name>D3PZ87_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5888"/>
    <dbReference type="EnsemblBacteria" id="ADD45516">
        <property type="protein sequence ID" value="ADD45516"/>
        <property type="gene ID" value="Snas_5888"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5888"/>
    <dbReference type="eggNOG" id="ENOG503279X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061199_2_0_11"/>
    <dbReference type="OMA" id="GWDIVYE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="241" mass="27052" checksum="AD10C33901447181" modified="2010-04-20" version="1">MLKVVGAGLPRTATWSQSEALPVLLGGKCYHMHQVIEHFDHVDTWIDALNGKTPDWHKFFDGYTAAVDWPASIFWPELAEAFPDALILLSTRTDAATWYRSMSNTVLKSLDMSRKAAEEGVDRPGFEGSPEKFLEMTDALWKRFVGEDSDVTADDAEGAQRCYDRYIQHVRDTAPADRLLEWNASEGWEPLCERLGLPVPEQPFPHSNTTADFQKMMESGPPGAGAATAEEYRQQMAQKDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZA5</accession>
    <name>D3PZA5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1883</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017150.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1883"/>
    <dbReference type="EnsemblBacteria" id="ADD41579">
        <property type="protein sequence ID" value="ADD41579"/>
        <property type="gene ID" value="Snas_1883"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1883"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="ITERPQA"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="148"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="215" mass="22911" checksum="868A030FDDF41DC3" modified="2010-04-20" version="1">MITVLIVDDEALVRAGIRMILAPVDDIEVVAEAADGAEALAAIDRDRPDVVLMDVRMPGMDGLTALRETLRRPAPPQVIMLTTFDMDEYVHGALHAGAAGFLLKDTPPRDLAAAVRTVAEGHAMLAPSVTRRLIDAYSGQPPVVGREARQRLAALTPRERDVIAAVALGLSNSQIAGRLGMTETTVKAHVSRSLTKLGLSNRVQLALLVRDAESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZC4</accession>
    <name>D3PZC4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1902</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017169.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1902"/>
    <dbReference type="EnsemblBacteria" id="ADD41598">
        <property type="protein sequence ID" value="ADD41598"/>
        <property type="gene ID" value="Snas_1902"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1902"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="VAHHISM"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="368"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="457" mass="46739" checksum="FBB414AFC7B3A38B" modified="2010-04-20" version="1">MAVVTGGSGAGRDGSTRARFRSGTLANRLSEHGFAVGAALLGAIATAESWIHAARAVAPEPNRPLLIAIIVLLGLASTVPVALADTRPALAAGLVTGALLVSMVATETLTFAGAAAQLVTGYQLGIRGPGPPSLDPAATAVGRPPTGLGARLSRLSALLFAAPFPLLALIALSGSVSQTQPGGAASTVTVESPVDVRGFVVRLALLAVLAPIAALAGIARRSAREAAAGRAAARTFADTLLEHTARGERARIARELHDVVAHHISMVAVQAETARLTTPGMPEAGAQRLRAIGDTARAALTEMRRLLGVLREDTGTEPARLQPQPGLRLRELNALLDETRDASGAGIRLVLKGQYAELDPGVELAAYRIIQEALTNARRHAPGAAVDVTLHYTQDELLMTIRDNGPGPSTTAPVGGHGLSGMRERAAAVGGQLTTTAASGGGFRVDVRLPTTDEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZN3</accession>
    <name>D3PZN3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019141.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3915"/>
    <dbReference type="EnsemblBacteria" id="ADD43570">
        <property type="protein sequence ID" value="ADD43570"/>
        <property type="gene ID" value="Snas_3915"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3915"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_26_0_11"/>
    <dbReference type="OMA" id="CFHRAFL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="198" mass="20826" checksum="EF53E73EE12D1B52" modified="2010-04-20" version="1">MSTRDKILDAAAEVIAERGLARATTKAIAAAAGYSEATLYKHFDSKTELFTAVLVERSPGDLSGALARLRRPESLDDHAAALTDVAAAAVDFYRQGFPMAASLFAEPELLRAHRADLERLGGGPHLAVAAVAAFLDECRARGEVAHGINVDAAAALLMGACFQRAFLSHFNGPDDDAGTTRAFAASITATLIAGMRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZR7</accession>
    <name>D3PZR7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Zinc-binding alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019175.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3952"/>
    <dbReference type="EnsemblBacteria" id="ADD43604">
        <property type="protein sequence ID" value="ADD43604"/>
        <property type="gene ID" value="Snas_3952"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3952"/>
    <dbReference type="eggNOG" id="COG1063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_826176_0_0_11"/>
    <dbReference type="OMA" id="GKMQNPV"/>
    <dbReference type="OrthoDB" id="1083526at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="372" mass="38055" checksum="15CF1F7B0808568B" modified="2010-04-20" version="1">MPVPSGSPIGLHRVLEPVGVLPQAALRLDASPEIRPDEVRIRVERLNLDAASYRQLREAHDGDGAAVRRAVREIIAERGKMHNPVTGSGGMLIGTVEEAGPESPLGLKAGDKVATLVSLTLTPLAIHDELADWDGGSEQVPCDGHAILFARSIAAVLPEDLPDTEALAVFDVCGAPAMTARVVERHRRATGKAPSVAVLGAAGKSGTLSLAAARDRGAGTAVGIVRTAAEAKALAARGLTDEIAVADATDAVAVSAAVLDRLAAADDPGANDMLTDAERRQMITGADITVVCVDVPGCEHGAILSTAEGGTVIFFSMATSFPTAALGAEGLAADVEMLIGNGYTPGHAAYALDLVRSHPGARSAFSARTSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZV6</accession>
    <name>D3PZV6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019214.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3991"/>
    <dbReference type="EnsemblBacteria" id="ADD43643">
        <property type="protein sequence ID" value="ADD43643"/>
        <property type="gene ID" value="Snas_3991"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3991"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_5_1_11"/>
    <dbReference type="OMA" id="RATYYIT"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="129" mass="13816" checksum="1DF699E9DE615634" modified="2010-04-20" version="1">MTDIKRIASGGPWEQLYGYVRAVKAGPWVISSGCTSTVDGKVVHVGDVAAQAKEAFRIALDSLVEAGASLTDVVRTRMYVTDPVHADPVGRAHGELFGLVKPAATLVVVSHLLHPDQLVEVEVEAYHQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q049</accession>
    <name>D3Q049_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5951</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021149.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5951"/>
    <dbReference type="EnsemblBacteria" id="ADD45578">
        <property type="protein sequence ID" value="ADD45578"/>
        <property type="gene ID" value="Snas_5951"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5951"/>
    <dbReference type="eggNOG" id="COG0488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_0_11"/>
    <dbReference type="OMA" id="RYFMDKI"/>
    <dbReference type="OrthoDB" id="1112046at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="5"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="334"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="297"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="369"/>
            <end position="376"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="558" mass="60926" checksum="4FF7560C590C1EFD" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0H0</accession>
    <name>D3Q0H0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017277.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2011"/>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41706">
        <property type="protein sequence ID" value="ADD41706"/>
        <property type="gene ID" value="Snas_2011"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2011"/>
    <dbReference type="eggNOG" id="COG3934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059722_0_0_11"/>
    <dbReference type="OMA" id="HSWVFNG"/>
    <dbReference type="OrthoDB" id="824395at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="405" mass="45002" checksum="8125C4EADAC0342F" modified="2010-04-20" version="1">MTAALGTRYGANYVPSSNWFYSWLDFSADAVRRDFDDLASIGLDHVRVFPMWPWIQPNRGHIRTKPIRDLLTVIDIAAERGLDVAVDLLQGHMSSFDFLPSWVLTHHHRSIFEDPDVRDGIASYMSTLSRAVADKPNVFAITLGNEVNNLVPFYSATPEATRDWASGLLNVVAEAAPDVLHLYSVYDASWYTPGHPFDPADSTDLGSLTTVHSWVFSGAAAIDGPLGPATVSHADYLIELAAATATDPARPIWLQEVGAPQPHVPATDAGEFTTQTLAHIDSNPALWGVTWWCSHDLDRRLLDFPEHEYDLGLFTLDHQPKPAARALERFIAQQRRPVTDRPAIVCPIDPRTQPERRDEIAPGSMFHDDWVRQRQQGPVAIVPPGERADTAYLAARGIDRVVIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0N9</accession>
    <name>D3Q0N9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_2081</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017346.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2081"/>
    <dbReference type="EnsemblBacteria" id="ADD41775">
        <property type="protein sequence ID" value="ADD41775"/>
        <property type="gene ID" value="Snas_2081"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2081"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_9_11"/>
    <dbReference type="OMA" id="YAYREGH"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="28"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="343"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="376"/>
            <end position="383"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD41775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="581" mass="61847" checksum="5E4C3E8629980D08" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0S1</accession>
    <name>D3Q0S1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017378.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2113"/>
    <dbReference type="EnsemblBacteria" id="ADD41807">
        <property type="protein sequence ID" value="ADD41807"/>
        <property type="gene ID" value="Snas_2113"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2113"/>
    <dbReference type="eggNOG" id="ENOG5030J64">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_833967_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="333" mass="35161" checksum="F3906722BC6E2EB1" modified="2010-04-20" version="1">MTYPPQQPQDWGGQQPYDPNQQGYGQQPQPGFDQQLPSYDLEPQPGQYQQDPYAQPQVDPYQPPQPSYDPAQYSAPPVSVAPASGQPYGGGPMLPPAAPKSSAPVWIFIVGGVVLLALIGVGVFFAIKSTGGSPDDDKTDSANEKSEEPSDDPPSASQSPSGDMIVDTNTGLGFKSMSGWQTMDTSAGIPVPGFTSFQGQQYEVTTDWVAMLGVGEIDASTLGYKDSGDLKDTVKAIAKEYDKNNFGKDPKGLDRDVKAEYDDADLAGKKAITMAYHLTWDKGENPDTGEQIVIAVIDVGGGKAAGFLGSLPDSTPKDQVDAAVEAAGTLAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q171</accession>
    <name>D3Q171_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021222.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6026"/>
    <dbReference type="EnsemblBacteria" id="ADD45651">
        <property type="protein sequence ID" value="ADD45651"/>
        <property type="gene ID" value="Snas_6026"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6026"/>
    <dbReference type="eggNOG" id="ENOG50318S9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1460438_0_0_11"/>
    <dbReference type="OMA" id="GHETWAP"/>
    <dbReference type="OrthoDB" id="1857303at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049631" evidence="2">
        <location>
            <begin position="39"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="19430" checksum="FE6293D24ECF81A8" modified="2010-04-20" version="1">MRRPATVTIAAVLQLLLAATFTVSVVTALLYGPAAQKAAESEMERQGLPKDALSGESLRFDEGWAGTVPATVIVLILVGLAVGNLRGKRSGRVLTWVLQPLLLVAGAVLVSGQVFLVRGIEAAFAGSGNPALADVDVPALVEAARSAFPAWYPVETWAKFVLVTLGSAVTIVLLALPRSRAFTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q191</accession>
    <name>D3Q191_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021242.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6047"/>
    <dbReference type="EnsemblBacteria" id="ADD45671">
        <property type="protein sequence ID" value="ADD45671"/>
        <property type="gene ID" value="Snas_6047"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6047"/>
    <dbReference type="HOGENOM" id="CLU_1805009_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="15728" checksum="6B2BEA82E5FA8045" modified="2010-04-20" version="1">MNQPGTSFGGELHKLHLFANVHVPAVADMYSDATELLNDTQAAAQNAFPHDDALDKASSEPHPEWEAMRQLLQRVLATNADNLLRVQEAVNNAVTAFTEQDEHAKRELDSIIKTGKGLDGRSYDNPSPPTEPDDVPREPVYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1D3</accession>
    <name>D3Q1D3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_6089</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021284.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6089"/>
    <dbReference type="EnsemblBacteria" id="ADD45713">
        <property type="protein sequence ID" value="ADD45713"/>
        <property type="gene ID" value="Snas_6089"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6089"/>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004585_5_2_11"/>
    <dbReference type="OMA" id="YQDTNRT"/>
    <dbReference type="OrthoDB" id="137860at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005751">
        <property type="entry name" value="ATP-dep_DNA_helicase_PcrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01073">
        <property type="entry name" value="pcrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="21"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="8">
        <location>
            <begin position="308"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="762" mass="84385" checksum="212DC6014756F2A4" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1M3</accession>
    <name>D3Q1M3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0151"/>
    <dbReference type="EnsemblBacteria" id="ADD39871">
        <property type="protein sequence ID" value="ADD39871"/>
        <property type="gene ID" value="Snas_0151"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0151"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_0_3_11"/>
    <dbReference type="OMA" id="SAEPRIW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048162" evidence="1">
        <location>
            <begin position="31"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="44"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="394" mass="43067" checksum="12670A6408E2FA62" modified="2010-04-20" version="1">MASRRTVLGLAGAATVAAGITVASSGIAEADSKVPDGLKPGGELDRYVKKLAAEGKFSGAFLLTHKRRKVLSRAYGMADAKAGVRNETDTRFKLASVTKMFTAVAINKLVQDDKVRYAEPIGKYIDGFSDEVAEKVTIHHLLLHTSGLGDFHDLPGYEEASRKWDTPDEVMNGTLDFIREDKLRFPPGAGWQYSNAAYCVLGGIIAAVSKQSYFDYVRDNVFEPARMRASDFYTRPQWQKDPKLAHPYFKDDETGEWVDRVDEQAYIGLPAGNSFATVGDMNRFANALLDAELLSRQFTHIMLTPKLPVGGGGKEPPPDPDKPRMTGFLGYGTFSSLIGDQRVHGFSGGSQAGPSTSIDIYPDSDWVTVILTNRDPSTVPEVNKIITKHILGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1N1</accession>
    <name>D3Q1N1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015450.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0159"/>
    <dbReference type="EnsemblBacteria" id="ADD39879">
        <property type="protein sequence ID" value="ADD39879"/>
        <property type="gene ID" value="Snas_0159"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0159"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_11"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="253" mass="26147" checksum="2D5F039F951D40CE" modified="2010-04-20" version="1">MSTRFAGKTVLITGGGSGIGREAARAFAAEGATVVVAGRREAPLKETVELVTAEGGTASFVTGDVTNEEDVRRIVATVAERHSRLDVAVNNAGVFAAGPLAEFELDQWQRLVDINVTGVLLSMKHELRQLKQQDGGGAIINVGSTVGAHKSVPGLAAYGASKAAVSALSRAAAAENIRDGIRINIVSPGSSDTPMSMRGGETEQQRAERLHETVPLGRVGQLDEVVSAVLWLASEGSGFAVGHDLVVDGGVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1R9</accession>
    <name>D3Q1R9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YCII-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015488.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0198"/>
    <dbReference type="EnsemblBacteria" id="ADD39917">
        <property type="protein sequence ID" value="ADD39917"/>
        <property type="gene ID" value="Snas_0198"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0198"/>
    <dbReference type="eggNOG" id="COG3795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130902_2_2_11"/>
    <dbReference type="OMA" id="KYLCQVW"/>
    <dbReference type="OrthoDB" id="2051456at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="116" mass="12876" checksum="6B8DF3B15A2269F2" modified="2010-04-20" version="1">MRYMLLIYGCDRPEPDDPKFAEAMASINAFAEECRRRGVLEAGEPLKRPETATTVRVREGQTLMTDGPFAETHEHLGGYYIIDCQNLDEALELAAMCPFAAEGTIEVRPLEADVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q260</accession>
    <name>D3Q260_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2237</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017498.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2237"/>
    <dbReference type="EnsemblBacteria" id="ADD41927">
        <property type="protein sequence ID" value="ADD41927"/>
        <property type="gene ID" value="Snas_2237"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2237"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_3_0_11"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="21499" checksum="F7B02D7B06A15C36" modified="2010-04-20" version="1">MSWHILVTFGLALLPIILTPGTSATLVAQYVSVGGRRHGAAVMAGTATGHFLHAGFATLGLSAVVMASATAFAIVRYAGAAYLVGLGIYLLVTSSRQRRQATGPAVAPPVARVYRHALIGNVVNPRAALIYLTVPAQVVAVDFPIAAAAFLLAVVHTVMMVSWLSLWTQAIASAKRSGLFKRIARQFSRVGGLLLIGLGIRAAVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q291</accession>
    <name>D3Q291_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019395.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4173"/>
    <dbReference type="EnsemblBacteria" id="ADD43824">
        <property type="protein sequence ID" value="ADD43824"/>
        <property type="gene ID" value="Snas_4173"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4173"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1188726_0_0_11"/>
    <dbReference type="OMA" id="LGDCIYA"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="26"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="233" mass="25527" checksum="BF1B03D95734701B" modified="2010-04-20" version="1">MAAMTLRQLSGRAWWYPADPDPAKVRGGVGVIADPDGSTVVDAGQSPAHARQVQAAIAEAGLPAARRLVYTHHHWDHTWGACAWDDVEIIGHDSGAALLANEARRPWSHEYLAEQMKADPLLEPSFSARAAAMDGWDDFTIVPPHTTFSDSLWVPGGIEVRHVGGQHTVDSTIVIDRESSVAFLGDCFYPPPYHLRQPGDTHDVGMIRALLAENLEWYVDSHSEPRRRSSIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2A9</accession>
    <name>D3Q2A9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DEAD/H associated domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4192</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019413.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4192"/>
    <dbReference type="EnsemblBacteria" id="ADD43842">
        <property type="protein sequence ID" value="ADD43842"/>
        <property type="gene ID" value="Snas_4192"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4192"/>
    <dbReference type="eggNOG" id="COG1201">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002025_3_1_11"/>
    <dbReference type="OMA" id="LPFWHGD"/>
    <dbReference type="OrthoDB" id="35275at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013701">
        <property type="entry name" value="DEAD/DEAH_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08494">
        <property type="entry name" value="DEAD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="32"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="263"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1289"/>
            <end position="1310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1534" mass="163247" checksum="DBD47DE3FE9F8F03" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2D5</accession>
    <name>D3Q2D5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019439.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43868">
        <property type="protein sequence ID" value="ADD43868"/>
        <property type="gene ID" value="Snas_4219"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4219"/>
    <dbReference type="HOGENOM" id="CLU_2540949_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="83" mass="8860" checksum="B1D0E26CE7366E8B" modified="2010-04-20" version="1">MGVTIPAIVFVGLLTLIVLCAMRGTTPSERVEILKAAASLAREWRHPILSLRRLPNVSTNGQAPVVDNGLPQITDGVNDKSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2G7</accession>
    <name>D3Q2G7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019471.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4251"/>
    <dbReference type="EnsemblBacteria" id="ADD43900">
        <property type="protein sequence ID" value="ADD43900"/>
        <property type="gene ID" value="Snas_4251"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4251"/>
    <dbReference type="HOGENOM" id="CLU_1069230_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="29597" checksum="0E5DE885163ECB81" modified="2010-04-20" version="1">MTKTDESFRILNHEIEVAEIMAAAAAFTVHRRSQIVVAKSRPEQEAEQLPAIARYTDHAHQTILAARTAIRDRYSPTSTVRLTTPQLPENTFHSGTPRRRQVTRALTVTLNRLWDIVGFVYDVINQPQVPRTDELADLVYFHTFAACGQWSIAHRAYQRATRRRRPRLNSEEFDLQTAGIAFALKGRIPDPVWQGFAEVMDGGEYCLILEDIVGVLIDNKLPVTIVEYDTLVSLLHYIELPNYRPALAERLTVSPIHDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2H1</accession>
    <name>D3Q2H1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4255"/>
    <dbReference type="EnsemblBacteria" id="ADD43904">
        <property type="protein sequence ID" value="ADD43904"/>
        <property type="gene ID" value="Snas_4255"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4255"/>
    <dbReference type="HOGENOM" id="CLU_1433687_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="189" mass="20959" checksum="7383E901499B0E25" modified="2010-04-20" version="1">MTILCGTLAGFSSYVLVSGDFKPADSAFTIGVVVSVAGTLLTVAAVLALVTLPRRSHSQPAIAVDMNGVWWVHRRNATLTTWQDLAGVGTSYKIAPQPHAQSSAGEIRRAFAFEAYLRESVLDDHPHAQLLRAWLVTDEPPHPDLPKQRLRYFLPVSGVRKELQRMVTHYAPQLWLGEYERDWNPLTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2N4</accession>
    <name>D3Q2N4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6162</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021356.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6162"/>
    <dbReference type="EnsemblBacteria" id="ADD45785">
        <property type="protein sequence ID" value="ADD45785"/>
        <property type="gene ID" value="Snas_6162"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6162"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_7_11"/>
    <dbReference type="OrthoDB" id="377638at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="7"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="409"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="487" mass="53024" checksum="E94B9DEF559B044D" modified="2010-04-20" version="1">MDAITLFRRSARRFGSRTALEDENGSLSFAELGDRVERLAHGLLSLGLRPGDRVLDLQSNQNTYVETDLACMAAGLVRVALNYRLHDTDWQRIAADCGARGIIYDPKFGDRAKSLIDALDASLSLGEEYERLIAKAPNATLETGDLVSLNYTSGTTGNPKGVRRAHSNRLASLTNMTIDVLGGLPGPDDVYLHAGPITHTSGLFVLPFLAAGAKQLIRSSFDETEVRDLVRAGHVTHTALVPTMIVRLLSTTDDPALRELKMLAYAGAPLPPEKIRQAHELLTPNLVQYYGLVEAIPPVTVLDAEDHRLGVTDNPDLLSSVGRAGTLIELRVIDDDGRELPPGEIGEVVTRGPHVMAGYWSAGDTVKAVRDGWLHTGDLGRMDAQGRLWLVDRKGDMIITGGYNVYPREIETVLAEVPGVEDVAVFGVDDPEWGQRVTAAFTGTATVEDLDAHCRARLASYKKPKEIRKLDAFPLNSTGKIDKRALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Q6</accession>
    <name>D3Q2Q6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021378.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45807">
        <property type="protein sequence ID" value="ADD45807"/>
        <property type="gene ID" value="Snas_6184"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6184"/>
    <dbReference type="HOGENOM" id="CLU_1694453_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="155" mass="16424" checksum="D19CC82E2F87E504" modified="2010-04-20" version="1">MEPKKPSKGLAVAAMVIGAFMCLIALWQFTKVVNAASYLMGIGSPVTVTVTGSSSGDEPMGQGYYESDGDRVDVWLAETDDRELVNTLLPVIPNSFVGEIVHNDKGTASSDLLGLISIAFFGTVGPLAVRGAWRNLKGKPPASLPFKPKRANASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2S2</accession>
    <name>D3Q2S2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6200"/>
    <dbReference type="EnsemblBacteria" id="ADD45823">
        <property type="protein sequence ID" value="ADD45823"/>
        <property type="gene ID" value="Snas_6200"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6200"/>
    <dbReference type="HOGENOM" id="CLU_555378_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="491" mass="53721" checksum="50610594D16CC25A" modified="2010-04-20" version="1">MNDAVPSPARDSARQRFSRALRRRGRRRLILDGVTLVVILLLALVVATNFSLPKEDPGPGWAKQEVLPEAEPVWTQGVGASDAALIHEDMLVHAYGSSNGIQATVSDLGTGDKVWHSNLDYPSVFLSGDYIIAMQALNGDEAVVYDIHSGKEVRTIKLTKFATVTVASGTLVSVEETGENDSRMRGFEVSTGKELWTKDLNKSHRQWTLGAPNDVWQTELFPELGIFDESTSPVVLLNRETASSSNVWDRVDAIDVATGEQRWVSPLDYGDVINPDEHGYMLTKSGDIFTEVTTGNPGDKETTSYVIDVSSGKETGYPEPADAFDYEVDTPLQGDFLSTSGKGWPQIKDVTNGKSLWRAKDEHSLLVHCGDVVFEEVDQEVDDPGEPAVEGVRVHDVATGKTLWTRQGSLESGPSSFGTSIGVGDDVVSTGFAKESEDEPPIQVFDRITGKGKWQIEGRLLAHNDDYFVFIDPDDASESAQLHVVSRKNPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2S5</accession>
    <name>D3Q2S5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021397.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6203"/>
    <dbReference type="EnsemblBacteria" id="ADD45826">
        <property type="protein sequence ID" value="ADD45826"/>
        <property type="gene ID" value="Snas_6203"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6203"/>
    <dbReference type="HOGENOM" id="CLU_2439329_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="90" mass="9835" checksum="2CC868174541D327" modified="2010-04-20" version="1">MDDRPQPSHGGTVDVENGRSRAGRAERTEIVHQLGLGAGRRSGGGFGVGFAGEFVQLFLRTQERGAVLPEQRVDADAVLWLEFLDDCHCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Y7</accession>
    <name>D3Q2Y7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0238</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015528.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0238"/>
    <dbReference type="EnsemblBacteria" id="ADD39957">
        <property type="protein sequence ID" value="ADD39957"/>
        <property type="gene ID" value="Snas_0238"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0238"/>
    <dbReference type="eggNOG" id="COG0628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031275_3_2_11"/>
    <dbReference type="OMA" id="WRTLTAY"/>
    <dbReference type="OrthoDB" id="944044at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="30"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD39957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="421" mass="45405" checksum="D4EC1A99800F5244" modified="2010-04-20" version="1">MSRFARFRMRASQTWARLRTNPYVERYEQVRRRNEDPELDDVPDEVEEEFADADEVEPPDPEGVPHGVKVAAGWSWRALVIAAAVVGVLYLASILSFVVIPILVSLLLAAMLQPLVALLVKAHVPRSIAAAIVLIAGIAAVAGVLTLVINQFVANIDTLVDSVQKGLLNLQDWAKYGPLHLEQKQINNFFSEFQTVITDWLSDNQSILAGTAVESLGIVFNILTGAFLVLFTTFFFMRDGRRIWTFLVRMLPERAHEPLLHAGFASWRTLVSFVRATILVAFIDAVGIGAWLMFLDIELAIPLAALVFLGAFIPIIGATVSGIVAVLVALVGDDWVTALLVLAGVIVVQQVEGHLLQPLLMGRAVSVHPLAIVLAVAAGVVLAGPIGALIAVPIVAVLNNGIKALRAHAHPPDETPGNVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3A4</accession>
    <name>D3Q3A4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017516.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2256"/>
    <dbReference type="EnsemblBacteria" id="ADD41945">
        <property type="protein sequence ID" value="ADD41945"/>
        <property type="gene ID" value="Snas_2256"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2256"/>
    <dbReference type="HOGENOM" id="CLU_155931_0_0_11"/>
    <dbReference type="OMA" id="ISARCVP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045635">
        <property type="entry name" value="DUF6412"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19950">
        <property type="entry name" value="DUF6412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="98" mass="10403" checksum="A33394AC3C843D37" modified="2010-04-20" version="1">MFPFRAVWWQLAIIFTFLLTLAVDHSDLGSVAASLAVAAAAAVLVGCGGAVWLSAVTRLAASLPAVADRSHRTVFVPQCDPDAAGRPRPRAPGWRVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3R2</accession>
    <name>D3Q3R2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019550.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4332"/>
    <dbReference type="EnsemblBacteria" id="ADD43979">
        <property type="protein sequence ID" value="ADD43979"/>
        <property type="gene ID" value="Snas_4332"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4332"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_5_0_11"/>
    <dbReference type="OMA" id="EKWVLHI"/>
    <dbReference type="OrthoDB" id="2057904at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="121" mass="13520" checksum="2ACF608129B7ECD7" modified="2010-04-20" version="1">MTEPVRCGPYFCGLDAAMDVVSGKWKSLVLWELEAHGTRRYGELKRNLPGISEKMLIQTLREMEADGLVHREVYKEVPPRVEYSLTEHGVALNTALAPLGAWGTERIGRIGADRVEIPESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q415</accession>
    <name>D3Q415_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_6280</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6280"/>
    <dbReference type="EnsemblBacteria" id="ADD45900">
        <property type="protein sequence ID" value="ADD45900"/>
        <property type="gene ID" value="Snas_6280"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6280"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_1_11"/>
    <dbReference type="OMA" id="GQHAFEW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="78"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="284" mass="31268" checksum="D9316222B080DAB6" modified="2010-04-20" version="1">MKQPKRLRKPWDATVLTRATLILAVLLSIWPLYWMIVIASRDISAATRIPPPLLPGGNLGDNIVRALSDESSHLMAGLVNSLIVSATVTVSVVFISTLAGFAFAKLRFRGSTVLLVTVLLTMMVPLQQIGVVPLYIMMVELGWVNTLQAVILPFLVNGFGIFLMRQYTIQAVPSELVESARMDGASTFRIYWNIVLPAVRPGIAVLALLTFMQNWNEFLWPLIVLQPDNPTVQLAIRGLSETNYGQDYSMIFTGTLLSIVPLVLVFIAFGRQIVGGLMEGAVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q421</accession>
    <name>D3Q421_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_6286</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021477.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6286"/>
    <dbReference type="EnsemblBacteria" id="ADD45906">
        <property type="protein sequence ID" value="ADD45906"/>
        <property type="gene ID" value="Snas_6286"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6286"/>
    <dbReference type="eggNOG" id="COG1108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028808_4_3_11"/>
    <dbReference type="OMA" id="WVVLRGM"/>
    <dbReference type="OrthoDB" id="1421296at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="292" mass="29731" checksum="DF604E22BBF54247" modified="2010-04-20" version="1">MDWITTPFEVGFVARAALAGLLVSAMCAVAGTWVVLRGMAFLGEAMSHGMLPGVAIAALLGGNLALGAMVSAGVVAAGVTGISRWRRLSQDTGIGLLFVGMLSLGVILVSRSQSFAVDLTGFLFGDVLSVRRSDLLILAAALLVTLVVGALGHRSFVALAFDHRKAATLGLRPRLAHAALLGLLALAMVASFQVVGTLLVFGLLIAPPAAVALWAGSVHMIMCGAAVLGAVATIGGLVISWHFDTAAGATIALATVTAFFLSAIATSLKRRPTAEVATVPSPRPAPELESTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q432</accession>
    <name>D3Q432_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021488.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6297"/>
    <dbReference type="EnsemblBacteria" id="ADD45917">
        <property type="protein sequence ID" value="ADD45917"/>
        <property type="gene ID" value="Snas_6297"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6297"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069607_0_0_11"/>
    <dbReference type="OMA" id="QPYLFPH"/>
    <dbReference type="OrthoDB" id="1745385at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="294" mass="31500" checksum="0192CA869C5843A1" modified="2010-04-20" version="1">MPTPEPTLQHPDLDDEPVADPLSLRLLRSELRLIATRRRNLVGLAVLCAVPVILAVVLALSNSAERSGTADAPPFVAMMFGNGLLVVTGTFSVECLVFIPLAMCMLAADSLSGEANAGTLRYLLTVPIGRTRLLFVKYAAASIAAVITIAAVAITGALTGFALFGTDELVTLSGAKIPFEESLWRVGLMCLYIMFMMVAFLAVAMFAATLTDQPAATVVGCLLYVLLDQLLVTTPDLAWLNPYLFTGYWRDWGDLLRQPIETANVTNGLIVAVVYAAVFLSAAWARLTTKDVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4E0</accession>
    <name>D3Q4E0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015671.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0383"/>
    <dbReference type="EnsemblBacteria" id="ADD40100">
        <property type="protein sequence ID" value="ADD40100"/>
        <property type="gene ID" value="Snas_0383"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0383"/>
    <dbReference type="HOGENOM" id="CLU_2013865_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049691" evidence="1">
        <location>
            <begin position="27"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="123" mass="13975" checksum="4C483EFFD3530C02" modified="2010-04-20" version="1">MRPKPTALATSLACLLAFSGCTTESDATKTEDITKRWKKHFTAADQPDSWQLYGRDTEKVTLTDNYLNIEGDIYNCEDTRVYWQMGRDWAKNVDDNVSTFVTVYDDDKLAGDTTTTGEFDCHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4S0</accession>
    <name>D3Q4S0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">6-phosphogluconolactonase</fullName>
            <shortName evidence="7">6PGL</shortName>
            <ecNumber evidence="5 7">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgl</name>
        <name evidence="9" type="ordered locus">Snas_2417</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="5 7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017671.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2417"/>
    <dbReference type="EnsemblBacteria" id="ADD42100">
        <property type="protein sequence ID" value="ADD42100"/>
        <property type="gene ID" value="Snas_2417"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2417"/>
    <dbReference type="eggNOG" id="COG0363">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053947_1_0_11"/>
    <dbReference type="OMA" id="YQLFEFE"/>
    <dbReference type="OrthoDB" id="1828393at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="PGLS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="PTHR11054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="8">
        <location>
            <begin position="10"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="257" mass="26950" checksum="B8DC62341EBA93CB" modified="2010-04-20" version="1">MTAASVAVHPDAEVLAQSVAARLATTIIDAQAERGEASIVLTGGRIAARFHSALAASPVRHAIDWSRVDFWWGDERFLPAGDPDRNETQARESLLAKLPVDPARVHPMPASDGPDGDDPEAAAARYAAELAAASRPGHQQHPHFDVVMLGVGEDAHVASVFPEQPAVYENRPVVAVRGAPKPPPRRITLTFPTINSADEVWLIASGGGKADAVALAMSGAGPKQAPAAAVAGATNTRWLLDKDAAAALPSKFRSLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4W6</accession>
    <name>D3Q4W6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Abortive infection protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2463"/>
    <dbReference type="EnsemblBacteria" id="ADD42146">
        <property type="protein sequence ID" value="ADD42146"/>
        <property type="gene ID" value="Snas_2463"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2463"/>
    <dbReference type="eggNOG" id="COG1266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086373_0_0_11"/>
    <dbReference type="OMA" id="RLSIGMH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="266" mass="29383" checksum="584079D517104467" modified="2010-04-20" version="1">MIVVDMETTTKPKGLAARLLADRHSLPLSIALHLVPGALIVAAYLYITEPFTKVIDYPPFLGWSLALCLVLFPLQLGLMWLGRKQTGRFSTRGVLQYTDKPLSRGKLAAFAIPAFLWFAVVSTALIPFDNVIYENFFTWVPFQGAGGSATAYLDGYSQSVLLTTMLISFLLTGVSLPLIEEIYFRGFLMPRLAHLGWGAPVLSTVLFSIYHLWSPWVVISRIIFFFPGPWLVWKTKDIRVSIGMHVGLTAISTFIGIIAIATGAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Y7</accession>
    <name>D3Q4Y7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">To bacterial alkanal monooxygenase alpha and beta chains.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017738.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42167">
        <property type="protein sequence ID" value="ADD42167"/>
        <property type="gene ID" value="Snas_2484"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2484"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_9_1_11"/>
    <dbReference type="OMA" id="PPFVLAM"/>
    <dbReference type="OrthoDB" id="1003376at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019949">
        <property type="entry name" value="Luciferase_OxRdatse_group-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03558">
        <property type="entry name" value="oxido_grp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="332" mass="35721" checksum="03EC58E6116A617F" modified="2010-04-20" version="1">MIPVPLSILDRSVIRRGQDPATALADTVRFARQAEQLGYRRFWVSEHHSVPGIAGSAPTVLAATIAQATTTIRVGTGGVMLPNHQPLIVAEQFGVLESLNPGRVDMGLGRSVGFTSGVRKALGHGKEDIDGFGEQLTELLGYFTGTQETHRGVHALPGEGLRPQPFVLAVGSGAAEAAARGLPLVIAPARGEDAMLASIARYREEFRPSVWAAEPHVVVALAVAVADTTEEARRLLLSESWSMARSRTTGAFEPLWPTADVLAHDLSDRERGFIDDSLAWAIYGTADDVDKELSTLVERAGAQEVLVTMNTFDRGEMLDSYRWLSELVADSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q500</accession>
    <name>D3Q500_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Coproporphyrin III ferrochelatase</fullName>
            <ecNumber evidence="7">4.99.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cpfC</name>
        <name evidence="9" type="ordered locus">Snas_2498</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Fe-coproporphyrin III + 2 H(+) = coproporphyrin III + Fe(2+)</text>
            <dbReference type="Rhea" id="RHEA:49572"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:68438"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="EC" id="4.99.1.9"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="6">
            <dbReference type="Rhea" id="RHEA:49574"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Porphyrin-containing compound metabolism; protoheme biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the ferrochelatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.9" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017751.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2498"/>
    <dbReference type="EnsemblBacteria" id="ADD42180">
        <property type="protein sequence ID" value="ADD42180"/>
        <property type="gene ID" value="Snas_2498"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2498"/>
    <dbReference type="eggNOG" id="COG0276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018884_2_0_11"/>
    <dbReference type="OMA" id="WLEPDIC"/>
    <dbReference type="OrthoDB" id="780534at2"/>
    <dbReference type="UniPathway" id="UPA00252"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="PTHR11108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00109">
        <property type="entry name" value="hemH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="2 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Fe-coproporphyrin III</name>
            <dbReference type="ChEBI" id="CHEBI:68438"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Fe-coproporphyrin III</name>
            <dbReference type="ChEBI" id="CHEBI:68438"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="341" mass="37157" checksum="0EE319083CCF721B" modified="2010-04-20" version="1">MNYDALLLVSFGGPESASDVLPFLRNVTRGRGVPEERLTEVAEHYYHFGGVSPINEWCRSFIDALRGEFATHRVNLPIYWGNRNWPPMLVEAVQQMAGDGVKRALAFTTSAYGSYSSCRQYLEDLSAARAAVGGSAPVIDKIRHFFDHPGFVQPFADKLRTAAAAIDDPANARILFTAHSIPVGMNDVSGPEGARYHDQVAETAALVRQAAGLDLPYDIVWQSKSGPADSVWLGPDINDHLKAIAAEGVSSVVVSPVGFLSDHMEVLWDLDIEAKQTAEELGLSYYRAGTPGLDPRTVTMVRELVAERVDGAPVKRLGKLPLWNPNDDGCCPARRPVGMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q516</accession>
    <name>D3Q516_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4419</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4419"/>
    <dbReference type="EnsemblBacteria" id="ADD44065">
        <property type="protein sequence ID" value="ADD44065"/>
        <property type="gene ID" value="Snas_4419"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4419"/>
    <dbReference type="HOGENOM" id="CLU_3239936_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="43" mass="5022" checksum="5BC45FDD82090910" modified="2010-04-20" version="1">MLRFVPVTAFVPAFDTRPVTASDTTTQSRDRYYAWSRRINTEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q519</accession>
    <name>D3Q519_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">GTPase Der</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP-binding protein EngA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">der</name>
        <name evidence="12" type="ordered locus">Snas_4423</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">GTPase that plays an essential role in the late steps of ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019639.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4423"/>
    <dbReference type="EnsemblBacteria" id="ADD44068">
        <property type="protein sequence ID" value="ADD44068"/>
        <property type="gene ID" value="Snas_4423"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4423"/>
    <dbReference type="eggNOG" id="COG1160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016077_6_2_11"/>
    <dbReference type="OMA" id="KFRFLEY"/>
    <dbReference type="OrthoDB" id="263682at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00195">
        <property type="entry name" value="GTPase_Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031166">
        <property type="entry name" value="G_ENGA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016484">
        <property type="entry name" value="GTP-bd_EngA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032859">
        <property type="entry name" value="KH_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14714">
        <property type="entry name" value="KH_dom-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006485">
        <property type="entry name" value="GTP-binding_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03594">
        <property type="entry name" value="GTPase_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51712">
        <property type="entry name" value="G_ENGA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="EngA-type G" evidence="11">
        <location>
            <begin position="23"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="EngA-type G" evidence="11">
        <location>
            <begin position="197"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="29"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="76"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="138"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="203"/>
            <end position="210"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="250"/>
            <end position="254"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="315"/>
            <end position="318"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD44068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="465" mass="50130" checksum="217FBC4A499F3894" modified="2010-04-20" version="1">MSAEPALDDFSNADTDTDTGPVPIVAVVGRPNVGKSTLVNRLIGRRQAVVEDVPGVTRDRIAYDAQWNGRKFTVVDTGGWEPDAVGRAAAIAAQAEQAIAASDVIVLVVDATVGATDVDDAAARVLHRAAKPVILVANKVDSVRAEADATQLWSMGLGEPHPISALHGRGSGDLLDIILDALPELPSVDDDTEGGPRRVALVGKPNVGKSSLLNRLAGEDRVVVDSVAGTTVDPVDSLIELGGETWQFVDTAGLRKRVKQASGTEYYASLRTQSAVEAAEVAVVLLDASEPISEQDQRVITQVVESGRALVIAFNKWDLVDEDRRFQISREIDRDLRRVQWAPRVNISAATGRSVAKLTPFLHTALEGWEQRVPTGELNQWVAALVAAHPHPIRGGKAPKVLFMTQASVRPPKFVVFTSGQLDPQYLRYIERRLREDFGFAGSPIVLSVKAREKRGKRSAKAGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q525</accession>
    <name>D3Q525_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tyrosine recombinase XerC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">xerC</name>
        <name evidence="13" type="ordered locus">Snas_4429</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the 'phage' integrase family. XerC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4429"/>
    <dbReference type="EnsemblBacteria" id="ADD44074">
        <property type="protein sequence ID" value="ADD44074"/>
        <property type="gene ID" value="Snas_4429"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4429"/>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_9_0_11"/>
    <dbReference type="OMA" id="HSFASHM"/>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 9" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0229">DNA integration</keyword>
    <keyword evidence="7 9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="12">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="11">
        <location>
            <begin position="112"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="9">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD44074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="301" mass="32527" checksum="C2F70512AA4ADEFC" modified="2010-04-20" version="1">MPARVVRDYLDHVTVERGHSANTIAAYRRDLGRYLDWLSETGLDALSQVTAADIGGYLARLSQGDDEHPGLSARSIARATSALRGLHRFALDEGVTDTDPTQALSTPKPALRLPKAIGVDEVARLLEAAAILDNPTGLRDTALVEFLYGTGARVSETIGADIDDLDFDAAAVRLRGKGGKVRVVPLGGYAVRALENYLTRARPSWTPGHPKLFVNSRGKPLTRQGVFFILRGLADRAGMAVDLGPHTLRHSFATHLLDGGADIRVVQELLGHAAVSTTQIYTLVTVDKLREVYATSHPRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q543</accession>
    <name>D3Q543_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative 3-methyladenine DNA glycosylase</fullName>
            <ecNumber evidence="5">3.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4447</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DNA glycosylase MPG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019663.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4447"/>
    <dbReference type="EnsemblBacteria" id="ADD44092">
        <property type="protein sequence ID" value="ADD44092"/>
        <property type="gene ID" value="Snas_4447"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4447"/>
    <dbReference type="eggNOG" id="COG2094">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060471_3_0_11"/>
    <dbReference type="OMA" id="VEAYHHT"/>
    <dbReference type="OrthoDB" id="1385409at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003905">
        <property type="term" value="F:alkylbase DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00540">
        <property type="entry name" value="AAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00527">
        <property type="entry name" value="3MGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003180">
        <property type="entry name" value="MPG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036995">
        <property type="entry name" value="MPG_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10429">
        <property type="entry name" value="PTHR10429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02245">
        <property type="entry name" value="Pur_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00567">
        <property type="entry name" value="3mg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="186"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="216" mass="23057" checksum="E7F699DD2F9C5F16" modified="2010-04-20" version="1">MTPRQLRDLLQGPVDEAAPGLLGCHVSHGGVTVRVTEVEAYSGEGLDPASHAHKGPTARNASQFGPPGHAYVYFIYGMHYCLNVVCYPEGIGGGVLLRAGAVVDGLDTARDRRGPMRDHDLARGPARLTMTLDVDRRHDGTPLLGGGPIDLTPGTQPVGEIRSGPRVGVSSAADVPWRFWIADDPSVSPYRRHVPKKRTGKNRSRATGADTSQLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q552</accession>
    <name>D3Q552_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4456"/>
    <dbReference type="EnsemblBacteria" id="ADD44101">
        <property type="protein sequence ID" value="ADD44101"/>
        <property type="gene ID" value="Snas_4456"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4456"/>
    <dbReference type="eggNOG" id="COG2378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041141_3_1_11"/>
    <dbReference type="OMA" id="MFERDKD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WYL" evidence="1">
        <location>
            <begin position="152"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="335" mass="37370" checksum="5B1E6DB84B58E9A1" modified="2010-04-20" version="1">MSVSRLRTERLVNLVICLLSTRRFLTADKIAATVPGYEHDSRDTRAHEAFQRKFERDKSELRRLGVPLETGTNSVFDSEPGYRIARHDYELPEFHLLPDEAAALGAAARLWQHSKLAADAGDGLWKLRAAGVDVRSDDEPEVAPVVTVDEAFSPVVSAVRHRREIRFDYLGKADDAAMKRKLQPWGVVCYRGKWYVVGHDLDRDAARCFRLSRISGKVAEHGPPDAYQVPGDLNLLDHVAAFHSDQPETPPRRATVLVAPGRAAGVRRQAEQISARRPDGDRLVIPYHDPHRLARRLAAYGPDVVVLEPDEVRKEMAVLLADVLGQYDSVTGGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5E8</accession>
    <name>D3Q5E8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal transduction protein with CBS domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6392</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021579.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6392"/>
    <dbReference type="EnsemblBacteria" id="ADD46008">
        <property type="protein sequence ID" value="ADD46008"/>
        <property type="gene ID" value="Snas_6392"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6392"/>
    <dbReference type="eggNOG" id="COG2905">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040681_12_1_11"/>
    <dbReference type="OMA" id="RDIIRCW"/>
    <dbReference type="OrthoDB" id="2014094at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="7"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="72"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD46008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="133" mass="14063" checksum="5FDEAFCFDC61E774" modified="2010-04-20" version="1">MQVKDAMSTTVLSIGPAHTLRKAAALMSARRVGAAVVVDPDAEGHGILTERDIMDSLAAGLDPDVERVGAHLTKDLVFAIPTWTLQEAAAAMVRGGFRHLIVVEGGEVVGVLSVRDVVRVWTKSTGRIPAELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5W2</accession>
    <name>D3Q5W2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015832.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0547"/>
    <dbReference type="EnsemblBacteria" id="ADD40261">
        <property type="protein sequence ID" value="ADD40261"/>
        <property type="gene ID" value="Snas_0547"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0547"/>
    <dbReference type="eggNOG" id="COG3211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018570_0_0_11"/>
    <dbReference type="OMA" id="WDIFVFG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008557">
        <property type="entry name" value="PhoX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05787">
        <property type="entry name" value="DUF839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="698" mass="76781" checksum="863F3A9074269752" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5Z9</accession>
    <name>D3Q5Z9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40298">
        <property type="protein sequence ID" value="ADD40298"/>
        <property type="gene ID" value="Snas_0584"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0584"/>
    <dbReference type="HOGENOM" id="CLU_3358668_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="36" mass="3024" checksum="2AC166B2AEB68483" modified="2010-04-20" version="1">MIPVPGSSDGTANGTAADGATGGADSGGDGTSAGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6L5</accession>
    <name>D3Q6L5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019829.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4615"/>
    <dbReference type="EnsemblBacteria" id="ADD44258">
        <property type="protein sequence ID" value="ADD44258"/>
        <property type="gene ID" value="Snas_4615"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4615"/>
    <dbReference type="eggNOG" id="COG4106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090249_0_0_11"/>
    <dbReference type="OMA" id="VPWKYYG"/>
    <dbReference type="OrthoDB" id="1739932at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="49"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="253" mass="27476" checksum="AB9CAB5F05418031" modified="2010-04-20" version="1">MNALTPDFARSWLARWDRQQEGYLPEREERFTAIIDAVEAGVDRPDPVIIDLGCGPGSLSVRLLDRLPKATVVAVDADPVLLALGEAAYGDRAGLRFVKADLVELGWTTALGLERPADAAVSTTALHWLDPTDLRRMYANLATVLAPGALFLNGDHLYVDKETRLAKLENALVDTLKDRVFGDNPPESWALWWDAVAADPVLAPLFAKREIAAHYGSPAGQLATHVEALDAAGFSEVGTIWQVGNDRVLCGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6L7</accession>
    <name>D3Q6L7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4617"/>
    <dbReference type="EnsemblBacteria" id="ADD44260">
        <property type="protein sequence ID" value="ADD44260"/>
        <property type="gene ID" value="Snas_4617"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4617"/>
    <dbReference type="HOGENOM" id="CLU_2525940_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="84" mass="9154" checksum="532449CF16846A30" modified="2010-04-20" version="1">MVDEDEPFGVDTSGVVGSGMTGRPRGMRHPLPDRNAVDAWLTEEPLLSPQEIVARMGELDPEGAKELLDREQAKRDARRGRAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q771</accession>
    <name>D3Q771_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="6">2.4.1.129</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2665</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.129" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2665"/>
    <dbReference type="EnsemblBacteria" id="ADD42342">
        <property type="protein sequence ID" value="ADD42342"/>
        <property type="gene ID" value="Snas_2665"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2665"/>
    <dbReference type="eggNOG" id="COG0768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009289_6_5_11"/>
    <dbReference type="OMA" id="HGKEEYY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="5">
        <location>
            <begin position="155"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="4">
        <location>
            <begin position="349"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="677" mass="72631" checksum="C943BC4B31A1EAD3" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q781</accession>
    <name>D3Q781_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2675</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2675"/>
    <dbReference type="EnsemblBacteria" id="ADD42352">
        <property type="protein sequence ID" value="ADD42352"/>
        <property type="gene ID" value="Snas_2675"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2675"/>
    <dbReference type="eggNOG" id="COG2311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036065_1_0_11"/>
    <dbReference type="OMA" id="FGMYVVH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012429">
        <property type="entry name" value="HGSNAT_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04235">
        <property type="entry name" value="DUF418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07786">
        <property type="entry name" value="HGSNAT_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="HGSNAT_cat" evidence="4">
        <location>
            <begin position="45"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="DUF418" evidence="3">
        <location>
            <begin position="323"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="434" mass="45203" checksum="BCDF4D8A27EEA94E" modified="2010-04-20" version="1">MTHSQLPQEKAAPQERASLSPLNPGTSDDPAPTAPPAKGDASMGRLVGVDLARALAVFGMYIVHVGPMLSTTSGVGSWIRYLADGHSSVLFATLAGFSLMLIAGRKEPKTGLAGRKAKARIAIRAVVLLAFGTLLAKFYGDVIIIGFYGVYFLVAMLFLKLSGKTLAITAAALAIVGPQLKFVLSPLLSGSVTQTVDAYDPLEKLSGVGVIDLLITGFYPTIPWIAFVVAGMALGRVDLSAPANQRRLAALGAGLTVAAYGLSLLLAGKNALRSMAEDGSSSGSGSWSGSGSGSWSGSSKPPMDSGSFGYQPSVSDLFAAGPHSGTTFDIIGSVGIAVLVIVGATFLMDRLPRLRRLMAPVVAVGTMSLTAYVGHFVIMSWLSLPGGGVRGSWIPVLTLILGAIVFAAIWSRFFKRGPLEYLLNLTTKPAKYVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7C0</accession>
    <name>D3Q7C0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017962.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2715"/>
    <dbReference type="EnsemblBacteria" id="ADD42391">
        <property type="protein sequence ID" value="ADD42391"/>
        <property type="gene ID" value="Snas_2715"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2715"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_1_11"/>
    <dbReference type="OMA" id="MMVLCEL"/>
    <dbReference type="OrthoDB" id="816674at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="393" mass="42930" checksum="4007AB66D3E35A8F" modified="2010-04-20" version="1">METPTLPFERTKVLELSPLARKLQEAGPIHRIRTAVGDPAWLVTRYAEVKELFGDNRLGRSHPDPASASRMNHSAVFGGGPTGEFDTEPEDAVRFRRLLQPLFSAKHMRLMQSRVDELVSGLLDPLEGATEPVDLHQALALPLPVLVICELLGVPLDDRDAFVAWSQDAGVVDDQARSEAGMANLMGYIYQLAMKKRANPGKDVLSAVAAAEHLPDEEVTRLGAGLLFAGHETTVTRIGFGVFLLLTKPEQWQSMLEDPELMSTAVEEILRAPVAGGLEGIPRYARSDIEFAGVTIKAGDLVILDLSAANHDPRAFADPDEFDVSRPANTHVGFGHGLHYCIGAPLARIELRSVFAQLPRRFPNLRLAVAPEDIEWRENQLTGGLKALPVSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Z5</accession>
    <name>D3Q7Z5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleoside triphosphate pyrophosphatase</fullName>
            <ecNumber evidence="2">3.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Nucleotide pyrophosphatase</fullName>
            <shortName evidence="2">Nucleotide PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + H2O = a 2'-deoxyribonucleoside 5'-phosphate + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:44644"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-phosphate + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23996"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Maf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.9" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016071.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0788"/>
    <dbReference type="EnsemblBacteria" id="ADD40500">
        <property type="protein sequence ID" value="ADD40500"/>
        <property type="gene ID" value="Snas_0788"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0788"/>
    <dbReference type="eggNOG" id="COG0424">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040416_1_2_11"/>
    <dbReference type="OMA" id="RIDGDFY"/>
    <dbReference type="OrthoDB" id="1469203at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036218">
        <property type="term" value="F:dTTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="PTHR43213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="199" mass="21335" checksum="2818189C948FFAA3" modified="2010-04-20" version="1">MRFILASASPARLTVLRGIGFDPEVIVSGVDESTIEEESPGRLCRALAKLKAKAVAATLTEDAYVLGCDSVLEFNGQTYGKAEDAETAVSRWKAMRGKSGVLHTGHCLIDTAKQRRHIRSSSTTVHFADVTDTEIAAYVDSGEPMRVAGAFTIDGLGAPFVERIEGDHGTVVGVSPPLLRQMFTAWGVPISSLWRTESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q806</accession>
    <name>D3Q806_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">M6 family metalloprotease domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0799</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016082.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0799"/>
    <dbReference type="EnsemblBacteria" id="ADD40511">
        <property type="protein sequence ID" value="ADD40511"/>
        <property type="gene ID" value="Snas_0799"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0799"/>
    <dbReference type="eggNOG" id="COG4412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010858_0_0_11"/>
    <dbReference type="OMA" id="KFARGPV"/>
    <dbReference type="OrthoDB" id="461923at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012300">
        <property type="entry name" value="Pept_M6_InhA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008757">
        <property type="entry name" value="Peptidase_M6-like_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05547">
        <property type="entry name" value="Peptidase_M6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007519">
        <property type="entry name" value="Protease_InhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03296">
        <property type="entry name" value="M6dom_TIGR03296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048933" evidence="2">
        <location>
            <begin position="30"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M6" evidence="3">
        <location>
            <begin position="89"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="744" mass="81563" checksum="F17D02BD12195CED" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q858</accession>
    <name>D3Q858_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0852"/>
    <dbReference type="EnsemblBacteria" id="ADD40563">
        <property type="protein sequence ID" value="ADD40563"/>
        <property type="gene ID" value="Snas_0852"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0852"/>
    <dbReference type="eggNOG" id="COG5395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078522_1_0_11"/>
    <dbReference type="OMA" id="WILHTHI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018750">
        <property type="entry name" value="DUF2306_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10067">
        <property type="entry name" value="DUF2306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="28700" checksum="60E8E54EB1A16EB6" modified="2010-04-20" version="1">MTAPTNRRPRVAWWRRPWVIPLGLGTVAFLAFSLPPYLSYDPAQTRVPAPPGFPEYYWILHTHIMFGTIALVTCCLQVWPWLRQRHPKIHRTSGRLYVLAGVLPSGLLALPVAIFSLSGPSAQTSSVLQALLWLGATIAGFRAARARRFREHRRWMVRSFALTTSIVVSRIWLVAVDAALKPTLETGFDGNELFFDQTVGGIAAWLSWVVNLLLAEWWLSRKPKRGGGRRPAPRTEGIGGAGSGGGEPKSAEVSLAAKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q863</accession>
    <name>D3Q863_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016139.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0857"/>
    <dbReference type="EnsemblBacteria" id="ADD40568">
        <property type="protein sequence ID" value="ADD40568"/>
        <property type="gene ID" value="Snas_0857"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0857"/>
    <dbReference type="eggNOG" id="COG0767">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045686_2_1_11"/>
    <dbReference type="OMA" id="LWIPRTL"/>
    <dbReference type="OrthoDB" id="1253502at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="262" mass="27577" checksum="900C98C9AD333A47" modified="2010-04-20" version="1">MLTSLGTQLQFYVRAIAWMPKAVVRYRKEVARLLGEVSFGAGGLTVVGGTVGVVVFLTFFTGTEVGLQGYQALNQVGTSAFTGFISAYFNTREIAPLVAGIALSATVGAGFTAQLGAMRVNEEVDALEVMGVRSLPYLVTTRMLAGLAACVPLYVLALLSSYVATRGVAIFYFGQSSGTYDHYFSTFLVPGDVLWSFGKVLCFSVIVIGVHCYYGYHASGGPAGVGVAVGRAVRTAIVAVNIVDFFVSLAVWGATTTVRIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q879</accession>
    <name>D3Q879_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018024.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2777"/>
    <dbReference type="EnsemblBacteria" id="ADD42453">
        <property type="protein sequence ID" value="ADD42453"/>
        <property type="gene ID" value="Snas_2777"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2777"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_11"/>
    <dbReference type="OMA" id="HEHQPRV"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="274" mass="28231" checksum="1CE6D833E43EA4D4" modified="2010-04-20" version="1">MNTIAPLPQETVSPRTAVITGSDSGIGRAIAAAFAGGGLNLGITYNRDEQGAKNTAAEARQLGAETTVRHLNLAELPEAADVIDELANELGGIDVLVNCSGTGSAEAMIDMDYDTWRNVVDIDLDGAFLCSQKAARQMISAGHGGRIINITSVHEHAPRVGAAPYCAAKAGLGALTKVMALELAQHDITVNSVAPGEISTPMTGQDNEDPREEPRPGIPAGRPGHAHEVAAVVAFLATPAAAYVTGASYVVDGGMTLMGPQASSALADEGWRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8B8</accession>
    <name>D3Q8B8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2816</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018063.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2816"/>
    <dbReference type="EnsemblBacteria" id="ADD42492">
        <property type="protein sequence ID" value="ADD42492"/>
        <property type="gene ID" value="Snas_2816"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2816"/>
    <dbReference type="eggNOG" id="COG1120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_11"/>
    <dbReference type="OMA" id="DMSHQLE"/>
    <dbReference type="OrthoDB" id="1048863at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="263" mass="28200" checksum="CC85570054561055" modified="2010-04-20" version="1">MTLESGLNAERVSLAYGDRVVSQDLSVAIRPGAFTAIIGPNGCGKSTLLRAFARLLNPKAGQVVLDGRDIATMRSKALARQLGLLPQSAIAPDGIRVVDLVARGRYPHQGAFDRWSERDEAAVATAMRETGVTEFSGRLVDELSGGQRQRVWIAMTLAQETATLLLDEPTTFLDIGHQIDVLNLFARINSSSGRTIVAVLHDLNHAARYADVVVAMRDGDIVAQGPPADVFTPGIVEKVFDLPCRVIEDPVAGTPLVVPVGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8K7</accession>
    <name>D3Q8K7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Malonyl CoA-acyl carrier protein transacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4808</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020020.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4808"/>
    <dbReference type="EnsemblBacteria" id="ADD44449">
        <property type="protein sequence ID" value="ADD44449"/>
        <property type="gene ID" value="Snas_4808"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4808"/>
    <dbReference type="eggNOG" id="COG0331">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030558_1_2_11"/>
    <dbReference type="OMA" id="AANYNCP"/>
    <dbReference type="OrthoDB" id="1123553at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="2">
        <location>
            <begin position="5"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="307" mass="31884" checksum="1B005887D273F98E" modified="2010-04-20" version="1">MLSVLAPGQGSQKPGFLIPWLELPGVAERLGSWSELIGIDLVHLGTTATQEEITDTAKTQPLLTAAALLAAEQLPIEDVDLVAGHSVGELGASVMAGVLTPEAALRLATARGREMAAACALTPTGMSAVLGGDDQVVREAIEQAGAYPANINGAGQVVAAGTTEALARLADNPPPGARVRSLSVAGAFHTPYMKPAQAKLTAFASTLEPADPERTWLSNADGSAMESGNQALLRLVAQVTTSVRWDECMKTMTKLGVTAIVELPPAGTLAGLAKRAMPGMEIVKVNTPDDLEAARDLINRNRKERTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8V9</accession>
    <name>D3Q8V9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase U61 LD-carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4910</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S66 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020122.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4910"/>
    <dbReference type="MEROPS" id="S66.001"/>
    <dbReference type="EnsemblBacteria" id="ADD44551">
        <property type="protein sequence ID" value="ADD44551"/>
        <property type="gene ID" value="Snas_4910"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4910"/>
    <dbReference type="eggNOG" id="COG1619">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034346_3_1_11"/>
    <dbReference type="OMA" id="MLTQWRL"/>
    <dbReference type="OrthoDB" id="952832at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027461">
        <property type="entry name" value="Carboxypeptidase_A_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027478">
        <property type="entry name" value="LdcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040449">
        <property type="entry name" value="Peptidase_S66_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040921">
        <property type="entry name" value="Peptidase_S66C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003507">
        <property type="entry name" value="S66_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237">
        <property type="entry name" value="PTHR30237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02016">
        <property type="entry name" value="Peptidase_S66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17676">
        <property type="entry name" value="Peptidase_S66C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028757">
        <property type="entry name" value="LD-carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141986">
        <property type="entry name" value="SSF141986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S66" evidence="4">
        <location>
            <begin position="17"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S66C" evidence="5">
        <location>
            <begin position="182"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR028757-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="32992" checksum="9A4D9FDF58563244" modified="2010-04-20" version="1">MAHNVIRPPRLRSGDTVRLISPSGPPENGKLESGIALLKSWGLTVQVSPHAYDRHGYLAGTDEVRAAELNAALRDPEVRGLFCTRGGYGLSRMVDAVDTDAAKADPKPVVGYSDITALFNTLYVHSGITGVHGPVMTSFISDRDASVGEALRQAVMTDEDVKLTPHPDEPTGVLTQGDAAVSGRLLGGNLSLVVDAVGTRTCPDYTGAILFCEEVNEEPYRLDRILTQLRRAGTLDGIVGIAIGQFTGCVDEDWDWDAVDVLGDRLSDLGVPILGGLRFGHGKDPFTVPFGTMATLDPVNRTLTAQSAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8W6</accession>
    <name>D3Q8W6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0864</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016146.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0864"/>
    <dbReference type="EnsemblBacteria" id="ADD40575">
        <property type="protein sequence ID" value="ADD40575"/>
        <property type="gene ID" value="Snas_0864"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0864"/>
    <dbReference type="eggNOG" id="ENOG503319D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1650367_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025341">
        <property type="entry name" value="DUF4247"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14042">
        <property type="entry name" value="DUF4247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="176" mass="18483" checksum="F6AFEC287A31FE65" modified="2010-04-20" version="1">MSSKASGWAVFGVIAVTGVVIASCAIASSSASPRKFIGKNYSCDVDPTEHDTASCDDSDSPANVATAIAADTQPVDTQRPADNVSSVECDDTTTADSEYGPDADLCADADLPRDDQTVYMQYEDDLVVVSKADTGCTVDVYDYDEGYRRHGAFFAVVGWTSTRPSSRGGGFSGFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9J7</accession>
    <name>D3Q9J7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018250.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3008"/>
    <dbReference type="EnsemblBacteria" id="ADD42679">
        <property type="protein sequence ID" value="ADD42679"/>
        <property type="gene ID" value="Snas_3008"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3008"/>
    <dbReference type="eggNOG" id="ENOG502ZQGS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_737520_0_0_11"/>
    <dbReference type="OrthoDB" id="1647498at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="357" mass="39077" checksum="354B4B40A7F7D03F" modified="2010-04-20" version="1">MKLYELRRANFETFRNTATVWKEAVDTFQAAGDDATNKVGDPIRNGTWEGDTGTAAGDKAKKLESQLDAAVTEASTVKQVLEEAAGLFKQHQDEVEQYAKQVDDNSRLSFTGDDGEIRILPPSGHSTLSGEAAKDAEDQLAKLRTDLQMKVQLGLAKARNLDNAVAEALLGASNMDESPDDPNFNVNAAQEGKLDLDSNNSKGDWLAFIGSIASRTGGSPEAQSAWLGDQVRKHVEAGGGVCKLVDGLMVCVGAPWYMYLRAGTTIGDTFISDYETFDAFERDRAGNSHGLIDHEKYHRDEQWRKYGYSFAAKYGGEELWTKLPFTDDTNKYEREAEDHGGDGGYNNPHGTGETKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9N7</accession>
    <name>D3Q9N7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4942</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020154.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4942"/>
    <dbReference type="EnsemblBacteria" id="ADD44583">
        <property type="protein sequence ID" value="ADD44583"/>
        <property type="gene ID" value="Snas_4942"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4942"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_14_2_11"/>
    <dbReference type="OMA" id="MNTHADR"/>
    <dbReference type="OrthoDB" id="1996723at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="5"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="3">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="157" mass="17576" checksum="B40A0CF6D30144DB" modified="2010-04-20" version="1">MAVRLVKGDKVADFALPDQTGTTRKLSEFLAEGPVVLFFYPAAMTRGCTMESCHFRDLATEFAEVGAQRVGISRDPVDKQRKFAEMNDFDYPLLSDREGAIAEQFGIKRSIPLGPLSIKRKTFVIDVDHTIMDVFHSEINMNGHADQALEVLRRRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Z8</accession>
    <name>D3Q9Z8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH marR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016281.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1000"/>
    <dbReference type="EnsemblBacteria" id="ADD40710">
        <property type="protein sequence ID" value="ADD40710"/>
        <property type="gene ID" value="Snas_1000"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1000"/>
    <dbReference type="eggNOG" id="COG1510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120349_0_0_11"/>
    <dbReference type="OMA" id="TLAFFEF"/>
    <dbReference type="OrthoDB" id="1646730at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="37"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="169" mass="19088" checksum="6CACCE4EC98BED56" modified="2010-04-20" version="1">MAGDPKHERDEDAIRAFVENFSLMLSERGVPRMAARVSTVMMVAEEDSLTAADLAERLGVSPAAVSGALKYLLHVGLFVRESIPNSRRDRYRFGDDNWYSAAILKTDFMNRAADEVDKLVEAVGGPGTHAGQRMTEMSDFYRFVTDELMNMYERWQQHKREREAAASAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA14</accession>
    <name>D3QA14_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Citrate synthase (unknown stereospecificity)</fullName>
            <ecNumber evidence="3">2.3.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1016</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; tricarboxylic acid cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.16" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016297.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1016"/>
    <dbReference type="EnsemblBacteria" id="ADD40726">
        <property type="protein sequence ID" value="ADD40726"/>
        <property type="gene ID" value="Snas_1016"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1016"/>
    <dbReference type="eggNOG" id="COG0372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025068_2_1_11"/>
    <dbReference type="OMA" id="YWTSAAE"/>
    <dbReference type="OrthoDB" id="1412360at2"/>
    <dbReference type="UniPathway" id="UPA00223"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="PTHR11739"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="366" mass="39724" checksum="47B341DB53DBF61A" modified="2010-04-20" version="1">MAEFKPGLEGVVAFETEIAEPDKQGGSLRYRGVDIEDLIGHASYGHVWGLLVDGAFGPGLPPAEPFPVPVHTGDIRVDVQSAVAMLAPYWGLGQLLDISDEQAREDLARVSVTALSYVAQSARGVGRPAVPQKEIDKSDTIVERFMRRWRGEPDPRHVKAVDAYFISAAEHGMNASTFTARVVASTGADVAACISSGIGALSGPLHGGAPSRVLHMLEEVERTGDAKTYVKGVLDRGERLMGFGHRVYRAEDPRARVLRRTAKELGSERYEVAEALEKAALAELKERKPDRVLATNVEFWSAVVLDFAQVPADMFTSMFTCARVAGWSAHVMEQKKLGRLVRPAATYVGPGPRKPETVPGWNEVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA41</accession>
    <name>D3QA41_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1043</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016324.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1043"/>
    <dbReference type="EnsemblBacteria" id="ADD40753">
        <property type="protein sequence ID" value="ADD40753"/>
        <property type="gene ID" value="Snas_1043"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1043"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_11"/>
    <dbReference type="OMA" id="IAFFIAW"/>
    <dbReference type="OrthoDB" id="1510342at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="65"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="273" mass="29452" checksum="FB6A969B35C06347" modified="2010-04-20" version="1">MFAKKAQWTVLDLVVIAFALIPVAWLTSLSLKDPSTIADGGFLPSKWTFDNYVNVFTDGGFLQPLVNSIGIALISTFVAILLGTFAAYAIARLEFPGRNIMLGAALLVAMFPQVSLVTPLFNIERNLGLFNTWPGLILPYVTFALPLTIYTMSTFFREIPWELEKAAKMDGASGFQAFRKVIVPLATPGVVTAAVLAFIQSWNDFLFAISLTSTERARTAPAAISFFTGASQFEDPTGSVSAAAVIVTIPIVIFVLIFQRRIVSGLTAGAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA47</accession>
    <name>D3QA47_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016330.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1049"/>
    <dbReference type="EnsemblBacteria" id="ADD40759">
        <property type="protein sequence ID" value="ADD40759"/>
        <property type="gene ID" value="Snas_1049"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1049"/>
    <dbReference type="HOGENOM" id="CLU_2195324_0_0_11"/>
    <dbReference type="OrthoDB" id="27945at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="SSF103647"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="108" mass="11823" checksum="11142C290BA5C637" modified="2010-04-20" version="1">MTDNETDKDKTYDLNGDGVPDEATKIGDTTYLDWDRDGKWDAMVTPEGDIYADLDGSYRFRTKALDTDGDGKIDTLETDLDGDGVADVIEKDIDGDGKFDEISGTDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA56</accession>
    <name>D3QA56_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anion-transporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016339.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1058"/>
    <dbReference type="EnsemblBacteria" id="ADD40768">
        <property type="protein sequence ID" value="ADD40768"/>
        <property type="gene ID" value="Snas_1058"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1058"/>
    <dbReference type="eggNOG" id="COG0003">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044079_0_0_11"/>
    <dbReference type="OMA" id="DAMMLDM"/>
    <dbReference type="OrthoDB" id="1347467at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="Anion-transp_ATPase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="PTHR10803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ArsA_ATPase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="373" mass="40024" checksum="D3AE3EA43D1E77CF" modified="2010-04-20" version="1">MEPPELDADALIANPDTKVVVCCGSGGVGKTTTAAALALRAAEVHGRQTVVLTIDPARRLAQSLGLAELDNTPRKVEKVTGGGLDAMMLDMKRTFDEVVLAHTTPEQAAEIFGNPFYQAMSGTFAGTQEYMAMEKLAQLRAKDQWDLIVVDTPPSRSALDFLDAPARLARFLDGRMLRILTASSRGGHSVFSLMTSSMSFFTRTINKILGGRMLTDIATFAASLDSTFGGFRTRAEATYRALQDPQTAFLVVAACEPDAIREAIYFTRRLTEERMPLAGLVLNRSHAVTAEGLSAERALGAAEGLEADGVDSATADTLRVHARLVTTVATETRIAARYTTACPSVPRTRVPAFPADVHDLDDLRAVGTAMTNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA63</accession>
    <name>D3QA63_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1065</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1065"/>
    <dbReference type="EnsemblBacteria" id="ADD40775">
        <property type="protein sequence ID" value="ADD40775"/>
        <property type="gene ID" value="Snas_1065"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1065"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_169_0_11"/>
    <dbReference type="OMA" id="VIMEYAQ"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="18"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="320"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="327"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="577" mass="61326" checksum="32099F45FCFC175A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA65</accession>
    <name>D3QA65_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016348.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1067"/>
    <dbReference type="EnsemblBacteria" id="ADD40777">
        <property type="protein sequence ID" value="ADD40777"/>
        <property type="gene ID" value="Snas_1067"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1067"/>
    <dbReference type="eggNOG" id="COG5164">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1694450_0_0_11"/>
    <dbReference type="OMA" id="FSTMQYS"/>
    <dbReference type="OrthoDB" id="1988676at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025557">
        <property type="entry name" value="DUF4282"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14110">
        <property type="entry name" value="DUF4282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="155" mass="17247" checksum="4BA9A5899B7B56DD" modified="2010-04-20" version="1">MTYPQDPQQQPEQQGGYPQGHTEQPSGHYQQQPDPSHYPPPTGAYQSQPIGGTGKNFFASLFDFSFRSFVTPQVIQIYYVVALVVLGIGVVFGLISAVITIAEFDAFLGLVQLILVPIFGFVYLLLVRMGLELVSNFFRIGEDVKAMREKSDRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA75</accession>
    <name>D3QA75_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016358.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1077"/>
    <dbReference type="EnsemblBacteria" id="ADD40787">
        <property type="protein sequence ID" value="ADD40787"/>
        <property type="gene ID" value="Snas_1077"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1077"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060076_0_0_11"/>
    <dbReference type="OMA" id="IAMNGVT"/>
    <dbReference type="OrthoDB" id="1339160at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="51"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="153"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="384" mass="42810" checksum="E41BC38ACE5872EE" modified="2010-04-20" version="1">MTSRIDIGIAVNGVTGRMGYRQHLVRSLLAIREQGGLPRPDGSVIWPELTLVGRNAAKLAEVAERHGIERYSTDLPEVLTDPSVSVYFDALTTQHRLAAVSSAIKAGKHVYCEKPIATSLDESLDLVRLAREHGVKNGAVADKLYLPGLLKLKRLIDSGFFGRILSVRGEFGYWVFEGDWQAAQRPSWNYRSEDGGGMALDMFPHWSYVFENLIAPVKSVTAHVSTHVPRRFDESGKGYPATADDAAYAIFELEGGVVAQMNSSWTTRVFRDELVEFQVDGTEGSAVAGLRRCRAQHRSVTPKPVWNPDIDQTVDFRSQWSEVPDNAEFDNGFKTQWEEFLRHVVDDAPWHHDFLAASRGVQLAEAGYLSSTEGRRVELPQLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA84</accession>
    <name>D3QA84_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ordered locus">Snas_1086</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016367.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1086"/>
    <dbReference type="EnsemblBacteria" id="ADD40796">
        <property type="protein sequence ID" value="ADD40796"/>
        <property type="gene ID" value="Snas_1086"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1086"/>
    <dbReference type="eggNOG" id="COG0234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132825_2_0_11"/>
    <dbReference type="OMA" id="EVKYSGE"/>
    <dbReference type="OrthoDB" id="1965002at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="98" mass="10473" checksum="21D767FCDCE1D6D1" modified="2010-04-20" version="1">MGVAIKPLEDRIVVQTNEAETTTASGIVIPDTAKEKPQEGTVLAVGPGRVDDKGNRVPIDVKTGDVVLYSKYGGTEVKYNGEDYLVLSARDVLAVIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAR1</accession>
    <name>D3QAR1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane-flanked domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5071</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020278.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5071"/>
    <dbReference type="EnsemblBacteria" id="ADD44707">
        <property type="protein sequence ID" value="ADD44707"/>
        <property type="gene ID" value="Snas_5071"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5071"/>
    <dbReference type="eggNOG" id="COG3428">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024617_1_0_11"/>
    <dbReference type="OMA" id="NIWAYAL"/>
    <dbReference type="OrthoDB" id="602555at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014529">
        <property type="entry name" value="UCP026631"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026631">
        <property type="entry name" value="UCP026631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="3">
        <location>
            <begin position="103"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="3">
        <location>
            <begin position="461"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="554" mass="59774" checksum="43EF24A8ED257800" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAX9</accession>
    <name>D3QAX9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5140"/>
    <dbReference type="EnsemblBacteria" id="ADD44775">
        <property type="protein sequence ID" value="ADD44775"/>
        <property type="gene ID" value="Snas_5140"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5140"/>
    <dbReference type="HOGENOM" id="CLU_333411_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="412"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="493"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="251"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="857" mass="93801" checksum="FBB704F83F534801" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB00</accession>
    <name>D3QB00_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016388.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1107"/>
    <dbReference type="EnsemblBacteria" id="ADD40817">
        <property type="protein sequence ID" value="ADD40817"/>
        <property type="gene ID" value="Snas_1107"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1107"/>
    <dbReference type="eggNOG" id="ENOG5030IE7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1271692_0_0_11"/>
    <dbReference type="OMA" id="VWVNIVN"/>
    <dbReference type="OrthoDB" id="1546812at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048386" evidence="1">
        <location>
            <begin position="33"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="195" mass="20700" checksum="EC998B0635E5B783" modified="2010-04-20" version="1">MDRRKLLTGAVLGTAIVGASALGGLAPEDAFAAETLKIEPGAPDPEFAEGLIKSINGNTFQATGSDTTLWRVRVTDSTSVWKLKPSRFEKIEVGDGMYARGVLMDDGTIAADSVWVNIVNIKAHVVSVKGRQLRLDHKGERIVAHMVDGTSAAVYNGRSAVSDLSGITVDSHVQVLGAWRPGTNEVDIATVYAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB57</accession>
    <name>D3QB57_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016445.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1164"/>
    <dbReference type="EnsemblBacteria" id="ADD40874">
        <property type="protein sequence ID" value="ADD40874"/>
        <property type="gene ID" value="Snas_1164"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1164"/>
    <dbReference type="eggNOG" id="ENOG502ZB65">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_876924_0_0_11"/>
    <dbReference type="OMA" id="GHLYMED"/>
    <dbReference type="OrthoDB" id="844909at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="36529" checksum="2ECBD9F30A6338C4" modified="2010-04-20" version="1">MTGEEPDHAEAEFLEETAASRVESVPLSHLSIELGHLYSEDYEADDDSLVEFFRQIGGWVRAAETRAAEFTGTRPRVSTCFMVDDYFGHFGGPREVVPRIEKLAHRAGVRIDYLARESACAAHGEVRPARLVEARIVAEPIPGDNGNRPPTSVSGWLSNGERSGERHTPGTGYAMGHRTDWQPPKETAANRHSVFVDVELWSEEADERVWSCAYLASVWQLLRLGLLRDNGDAVGVPAARPEALPSSWDEMPAVTRLEEGADPFNAYRTLSIMDSRFLRVEDAVRVILNQIAVESEVDAEVLRRAKAERMRLPSEPVDRLEYVFTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBR8</accession>
    <name>D3QBR8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020378.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5172"/>
    <dbReference type="EnsemblBacteria" id="ADD44807">
        <property type="protein sequence ID" value="ADD44807"/>
        <property type="gene ID" value="Snas_5172"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5172"/>
    <dbReference type="eggNOG" id="COG0406">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_13_1_11"/>
    <dbReference type="OMA" id="VCGFEHG"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="191" mass="20662" checksum="3FF7DE997A064AEE" modified="2010-04-20" version="1">MGSIVLVRHGQTEWSRSGRHTSVTDLDLTDDGERQARNLAPALTPYRFTAVWCSPMRRARHTAALAGLTVTTTSADLAEWNYGRYEGVTTATIRETVPDWSIWRDGCPDGESPSAIGARLDRALTAIRPLLTDGDVAVVGHGHALRVAAARWIGLPPSGGALLGLDTASISVLGHEREQPVLRHWNLTPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBU9</accession>
    <name>D3QBU9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5203</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020409.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5203"/>
    <dbReference type="EnsemblBacteria" id="ADD44838">
        <property type="protein sequence ID" value="ADD44838"/>
        <property type="gene ID" value="Snas_5203"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5203"/>
    <dbReference type="eggNOG" id="COG3795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2132017_0_0_11"/>
    <dbReference type="OrthoDB" id="2011567at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="113" mass="12802" checksum="887B7D9B634853C5" modified="2010-04-20" version="1">MRFMLLIYDNAEPDRPTRSVHRDEWRRRLTVTGEWVSGRLLADACLTRTVRVGHGDTEVRSGGSTGAGRRLVGCFEVECESFERAVRIAAEAPWPARRTVEVRPLMDEAGLEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU19</accession>
    <name>D3PU19_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1255</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1255"/>
    <dbReference type="MEROPS" id="S08.051"/>
    <dbReference type="EnsemblBacteria" id="ADD40965">
        <property type="protein sequence ID" value="ADD40965"/>
        <property type="gene ID" value="Snas_1255"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1255"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_1_7_11"/>
    <dbReference type="OMA" id="INWRTAS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048568" evidence="5">
        <location>
            <begin position="34"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="6">
        <location>
            <begin position="539"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="601" mass="61238" checksum="FBDFB13C23C00814" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUG1</accession>
    <name>D3PUG1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD-superfamily hydrolase, subfamily IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018545.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3307"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42974">
        <property type="protein sequence ID" value="ADD42974"/>
        <property type="gene ID" value="Snas_3307"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3307"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_0_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="220"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="735" mass="80652" checksum="2C0D437D0EABC509" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUI3</accession>
    <name>D3PUI3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3330</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018567.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3330"/>
    <dbReference type="EnsemblBacteria" id="ADD42996">
        <property type="protein sequence ID" value="ADD42996"/>
        <property type="gene ID" value="Snas_3330"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3330"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="HEYATII"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="343" mass="36690" checksum="A20D414628F07FE3" modified="2010-04-20" version="1">MARRSVPHRPTIADVAALAGVSKGAVSRAFNGGERISAATIQRIHDAATQLGWVPSAAARAINGAPTQAVGIVVRRPPELLDIDPFFPAFLAGVETVLARHEYATIIRFVEGAKQERACYERMMAERQVDGFLLNDLRRPDFRFRLLSGMGAPAVVVGTPGPSCPYPSVDSDSTPRVRQLIEHLIAMGHRRIAHVTGVPELLHSRARETLWRQTLADHGIEPGPVAVGNFVAAGGAQATRQLLAEPRRPSAIFYGNDVMAVGGMAVLAEHGLRVPEDVAVAGFDDIELASYLTPALSTVHCDYPGLGRAAAEMLLTAIGGTAPSWRVTLPTQVRLRRSTANTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUQ7</accession>
    <name>D3PUQ7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020502.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5297"/>
    <dbReference type="EnsemblBacteria" id="ADD44931">
        <property type="protein sequence ID" value="ADD44931"/>
        <property type="gene ID" value="Snas_5297"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5297"/>
    <dbReference type="HOGENOM" id="CLU_2071696_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048590" evidence="2">
        <location>
            <begin position="16"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="118" mass="12316" checksum="882D476C7DC192C8" modified="2010-04-20" version="1">MASRLATVPPPPVLAAFVLALATGLVWMVLALWPAPGEPGGGLFFPMTGLLLAVFTAFCVWQGERRGNLLVAVLFGVIPCLALLTSPRLGILQAAMGAALIVLLTVPTVSRQWFGYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUW4</accession>
    <name>D3PUW4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5355</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5355"/>
    <dbReference type="EnsemblBacteria" id="ADD44988">
        <property type="protein sequence ID" value="ADD44988"/>
        <property type="gene ID" value="Snas_5355"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5355"/>
    <dbReference type="eggNOG" id="COG1052">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_1_11"/>
    <dbReference type="OMA" id="TAYYTDH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="4">
        <location>
            <begin position="26"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="5">
        <location>
            <begin position="109"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="319" mass="35279" checksum="D581A076CDB8E42E" modified="2010-04-20" version="1">MGITVYGCGQDEAVLFREMSPSYGVTPTITPAPLTEANVELAFGNRCVSVGHKTRITDATLRALNRIGTNYISTRSIGYNHINVDYAKTLDITVENVSYSPDSVADYTLMLMLMVVRSAKSIIRRTDVHDYRLNDVCGRELRDLTVGVIGTGRIGAAVMDRLWGFGCRVLTHDRRHKTGADHVPLDQLLRQSDMVTLHTPLNASTHHLLNRTRLEQMKPGAYVINTGRGSLIDTEALVPALESGRLGGAALDVIEGEEGVFYADCRNKVIESKSLLRLQELPNVLISPHTAYYTDHALSDTVENSIINCQKFENRNQHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUW9</accession>
    <name>D3PUW9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5360"/>
    <dbReference type="EnsemblBacteria" id="ADD44993">
        <property type="protein sequence ID" value="ADD44993"/>
        <property type="gene ID" value="Snas_5360"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5360"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="HIAYSAY"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="793"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="833"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="913" mass="100046" checksum="F92A7A0482E78761" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV47</accession>
    <name>D3PV47_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylmalonyl-CoA mutase, large subunit</fullName>
            <ecNumber evidence="4">5.4.99.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1393</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.2" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016671.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1393"/>
    <dbReference type="EnsemblBacteria" id="ADD41100">
        <property type="protein sequence ID" value="ADD41100"/>
        <property type="gene ID" value="Snas_1393"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1393"/>
    <dbReference type="eggNOG" id="COG1884">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009523_5_1_11"/>
    <dbReference type="OMA" id="CGVAIDS"/>
    <dbReference type="OrthoDB" id="154460at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004494">
        <property type="term" value="F:methylmalonyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006098">
        <property type="entry name" value="MMCoA_mutase_a_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00641">
        <property type="entry name" value="acid_CoA_mut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="METMALONYL_COA_MUTASE" evidence="3">
        <location>
            <begin position="28"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="578" mass="63171" checksum="E09756D4ED3B754A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV77</accession>
    <name>D3PV77_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1424"/>
    <dbReference type="EnsemblBacteria" id="ADD41130">
        <property type="protein sequence ID" value="ADD41130"/>
        <property type="gene ID" value="Snas_1424"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1424"/>
    <dbReference type="eggNOG" id="ENOG5033MK7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1137484_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="242" mass="25927" checksum="44EBACE07436D0F5" modified="2010-04-20" version="1">MTMRFDTETGVLRLDQASFDSLVTWYGDGMPDGPDLAELHEAGASTAGHPHPDVANGLEAVTGYRSRLRLDCVDHTGEELTGDGWAGLADAALLLDSEEGLRDFLALRPELIPVMVARIVHLGPRPRVDAEAVRLPRDVFEGLLGATEPERAAAAERCGGEPTNVIGALVDGPWLYWTVTSSWYTPEGEPASRAVRVVDTVAGLWSIHMDGMSVSMTPTNATAIWRGLSGLIPAETEEPEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVF0</accession>
    <name>D3PVF0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018635.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3400"/>
    <dbReference type="EnsemblBacteria" id="ADD43064">
        <property type="protein sequence ID" value="ADD43064"/>
        <property type="gene ID" value="Snas_3400"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3400"/>
    <dbReference type="eggNOG" id="COG5483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077467_3_0_11"/>
    <dbReference type="OMA" id="EYAWANS"/>
    <dbReference type="OrthoDB" id="1831995at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007438">
        <property type="entry name" value="DUF488"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04343">
        <property type="entry name" value="DUF488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="161" mass="18212" checksum="A35A647E7C8C4D44" modified="2010-04-20" version="1">MGKLVTIGVYDFDAESFLQRLRHADVRVLFDVRQRRGVRGSEYAWANSQRLQAALAEAGIAYEHHPELAPTTELRRLQYAEDDRNSVGKRSRRELADEYIRRYTAEILDGADLAPIVSALPSHGTGALFCVERDPEACHRSLIARLLAETQDVTIEHLRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVM4</accession>
    <name>D3PVM4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nickel-dependent hydrogenase large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3474</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018709.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3474"/>
    <dbReference type="EnsemblBacteria" id="ADD43138">
        <property type="protein sequence ID" value="ADD43138"/>
        <property type="gene ID" value="Snas_3474"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3474"/>
    <dbReference type="eggNOG" id="COG3259">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044556_0_0_11"/>
    <dbReference type="OMA" id="QNNLAMN"/>
    <dbReference type="OrthoDB" id="1967820at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008901">
        <property type="term" value="F:ferredoxin hydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001501">
        <property type="entry name" value="Ni-dep_hyd_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018194">
        <property type="entry name" value="Ni-dep_hyd_lsu_Ni_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00374">
        <property type="entry name" value="NiFeSe_Hases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00508">
        <property type="entry name" value="NI_HGENASE_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="432" mass="47623" checksum="9D32C2F36220590A" modified="2010-04-20" version="1">MTHRHDRLLHVAALARVEGEGAMRVRVTGDTVTEVQLDIYEPPRFFEALLRGRGHTEPPDITSRICGICPVAYQMSACAAIEDACGITVDSGIQDLRRLLYCGEWISSHALHIYLLHAPDFLGYSGAVDMARDQRPVVERGLRLKQAGNMIMERLGGRAIHPVNVRIGGFHRLPTRTELDSLVAPLTRALDDALDTVTMAAGFDFPEYECRHEWLALVDPRQRYPIDGGVPHTSQGSFPLREYTSHVVEHQVSHSTALHARLADGSRPLTGPLARYALNHDRLSPLARQTARSAGLDSVCRNPFRSIIVRAVETVYAVEEALRIIASYEPPPRPAVPVPPVAAIGYGATEAPRGVLFHSYTLDDSGTVLAANIVPPTAQNQTAMEHDLRGFVQDHLTLDDHSLTHACEQAIRNYDPCISCSTHFLDLTVERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW26</accession>
    <name>D3PW26_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5516</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5516"/>
    <dbReference type="EnsemblBacteria" id="ADD45147">
        <property type="protein sequence ID" value="ADD45147"/>
        <property type="gene ID" value="Snas_5516"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5516"/>
    <dbReference type="eggNOG" id="COG4166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_0_3_11"/>
    <dbReference type="OMA" id="TMLDTMH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049293" evidence="1">
        <location>
            <begin position="32"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="76"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="528" mass="58374" checksum="F5963A3D1BB8B222" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW63</accession>
    <name>D3PW63_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016791.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1516"/>
    <dbReference type="EnsemblBacteria" id="ADD41220">
        <property type="protein sequence ID" value="ADD41220"/>
        <property type="gene ID" value="Snas_1516"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1516"/>
    <dbReference type="eggNOG" id="COG3173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105423_0_0_11"/>
    <dbReference type="OMA" id="CEWIVRM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="15"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="111"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="229" mass="25160" checksum="FC92B87E22708367" modified="2010-04-20" version="1">MYGVDASEQPQRMPHGYCNDTVHHDDAVIKRFTGPDAAARASTEVRALRAAFPTVPVPQVKAASDAEITCEFVPGVHGQDLIGPDTAARLLAECGRVLATIHAVPVAAVQAEPHPAGVLIHGDFGPQNMLFDKETLTVAAVLDWEWAHIGQPLEDLAWCEWIVRSHHADCVDALPHLYHGYGAPMPPWPRRQAAMLGKCRAMRQFGARRQDGSATVWQRRTAITQAWRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWP3</accession>
    <name>D3PWP3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NTPase (NACHT family)-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3605"/>
    <dbReference type="EnsemblBacteria" id="ADD43265">
        <property type="protein sequence ID" value="ADD43265"/>
        <property type="gene ID" value="Snas_3605"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3605"/>
    <dbReference type="eggNOG" id="COG5635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_268211_0_0_11"/>
    <dbReference type="OMA" id="HERVHRY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="251"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1225" mass="135378" checksum="C9F583AE465064B1" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWP8</accession>
    <name>D3PWP8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018841.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43270">
        <property type="protein sequence ID" value="ADD43270"/>
        <property type="gene ID" value="Snas_3610"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3610"/>
    <dbReference type="HOGENOM" id="CLU_2453176_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="89" mass="9200" checksum="2AD69E9ADB19222B" modified="2010-04-20" version="1">MDILPIPDDAAGTIPAATQHRLTELAAQLTADVTWAASTATDALKQIHTDQFHKGSENLGAAARIMTTAATSASVLAEVSRTISDIVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWR9</accession>
    <name>D3PWR9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018862.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3631"/>
    <dbReference type="EnsemblBacteria" id="ADD43291">
        <property type="protein sequence ID" value="ADD43291"/>
        <property type="gene ID" value="Snas_3631"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3631"/>
    <dbReference type="HOGENOM" id="CLU_1585465_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="18763" checksum="0452222B24589195" modified="2010-04-20" version="1">MNVDIAILGVLIIAAVTTYFLRGKKPRRILDELCKEDTIATSLRLSQVRGIVLRALRHPLGALVVENPNHFECSFSHRVRGVAYTVALRIDLHVRSTHRANGVWVRVGVVEMDFPGTMTDPAFRAAFGDVVVLRKRVIRALATADITSTRSTVNITWAHRTHCVRAGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWT8</accession>
    <name>D3PWT8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5531</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020733.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5531"/>
    <dbReference type="EnsemblBacteria" id="ADD45162">
        <property type="protein sequence ID" value="ADD45162"/>
        <property type="gene ID" value="Snas_5531"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5531"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="IFRDSRQ"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="963" mass="103954" checksum="5638EEC5666CD2EC" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX75</accession>
    <name>D3PX75_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD-dependent pyridine nucleotide-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1635</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016909.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1635"/>
    <dbReference type="EnsemblBacteria" id="ADD41338">
        <property type="protein sequence ID" value="ADD41338"/>
        <property type="gene ID" value="Snas_1635"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1635"/>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003291_4_0_11"/>
    <dbReference type="OMA" id="QFDARIQ"/>
    <dbReference type="OrthoDB" id="1149616at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028202">
        <property type="entry name" value="Reductase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14759">
        <property type="entry name" value="Reductase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="4"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="240"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Reductase_C" evidence="3">
        <location>
            <begin position="430"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="497" mass="50685" checksum="C42EF40B585E1706" modified="2010-04-20" version="1">MTGDVVIVGASAGGLTVAEVLRRKGFDGRIRLVGAEVHPPYDRPPLSKEILTGAWGPERALLRDDERLDALGAEFILGRHARHLDLTERTVKLDDGRTLGFGSLVIATGVTPRRLGCQRELAGVSTFRTLDDAMALRRELAGPEPGASPATAQTVAGGGGPASTGAGGGNPDASPATAQTDAGGSDPHAAAAGSGNPDAAGAGDGVSAPVEAWPSAHSGFGSAVARPTATATPAAQRAATGTTAARQAATGPPAARRVVIVGAGVLGCEIAAAARELGHEVTLVEPGPVPMERQLGLRVGGHVAAMHRDRGVKLRTGVNVTAFLGTERLSGVELSDGSVLAAELAVVTAGSVPATGWLANSGLGLVDGVECDEYGRAAPGVYAVGDVARWRHPVTGVSSRIETRTNASEQAMTVATNILGGNRCPTPVPYFWSDQYDTRIQLYGTVTPHSHIRVIDGAVDDGRFVALAETGDTVTAAIGWNNPRGTRTARARLTAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXF1</accession>
    <name>D3PXF1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016985.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1715"/>
    <dbReference type="EnsemblBacteria" id="ADD41414">
        <property type="protein sequence ID" value="ADD41414"/>
        <property type="gene ID" value="Snas_1715"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1715"/>
    <dbReference type="eggNOG" id="COG4430">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076645_1_1_11"/>
    <dbReference type="OMA" id="WENTATG"/>
    <dbReference type="OrthoDB" id="1966598at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="183" mass="20240" checksum="8AB9F1210021308E" modified="2010-04-20" version="1">MDILDFPDVAAWEAWLERNHGEHTEAWLRIAKKNSPLTTLAIGDALDGALCFGWIDGQRKGLDEASFLQRYSKRRRRSSWSQVNVAKAESLIAAGRMRPAGFAEIEAAKADGRWDAAYVKQSEFTVPSDVATALAGNPTAAAAFGELGKSDQYLLVLPLLKTRTPETRAKSLNRLLERLTDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXP0</accession>
    <name>D3PXP0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018941.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43370">
        <property type="protein sequence ID" value="ADD43370"/>
        <property type="gene ID" value="Snas_3713"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3713"/>
    <dbReference type="HOGENOM" id="CLU_1730284_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049334" evidence="1">
        <location>
            <begin position="27"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="151" mass="16558" checksum="9C928C9CD5AF3BE1" modified="2010-04-20" version="1">MSIRTLLAATFAGLLAVVLLAAPASAHDHDHADGTLTLEYLGTDTDAADTDVVAKDHGQHGHTYPPDIDGYVPTSYGGDCYDNVLAYASWHSEGDWYIVYDKCEMERYGAGQSDWDRVGAHEKAHTDGWGHYEEPRDRNAAFEPGIVICRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYG1</accession>
    <name>D3PYG1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidoglycan-binding domain 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1832"/>
    <dbReference type="CAZy" id="GH75">
        <property type="family name" value="Glycoside Hydrolase Family 75"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41528">
        <property type="protein sequence ID" value="ADD41528"/>
        <property type="gene ID" value="Snas_1832"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1832"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_732886_0_0_11"/>
    <dbReference type="OMA" id="NGEYAED"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016977">
        <property type="term" value="F:chitosanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009939">
        <property type="entry name" value="Chitosanase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42061">
        <property type="entry name" value="PTHR42061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07335">
        <property type="entry name" value="Glyco_hydro_75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048463" evidence="1">
        <location>
            <begin position="26"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="249"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="319"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="379" mass="38840" checksum="EC0AC04C7C44A69B" modified="2010-04-20" version="1">MRRSLIAVAGVVALAASLTGAWAFASGTDDGGGKAEGPTADQLREAVNGCDTQLSNGEYAEDADGSGSIPVCKSAGGAVHWKSDFDIDCDGQRTDECNENTDPSWQNETAFPQSDGQPLNSATLPHIVVPLPSDKWDYKGEGIEGGTVAAVTYEDKVVYAVVGDLGPKPIIGEGSYALAEALGIDPDPATGGVSGKVVDFILFPGVKATPIEDPAQSESLGSEAANKLVGGCAGYGFKAYPDLATGSKGSEVRAAQCLLADAGFPTGDKPSGSFDDKTVTATKEFQTKVGLEASGKVDKHTWTALLSMGETPELKEGSSGADVSRVQRALTAALGAEVSQDGQFGPKTKQAVTDYQTAAGVEANGVVNAETWKALQAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYI4</accession>
    <name>D3PYI4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1855"/>
    <dbReference type="EnsemblBacteria" id="ADD41551">
        <property type="protein sequence ID" value="ADD41551"/>
        <property type="gene ID" value="Snas_1855"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1855"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_762138_0_0_11"/>
    <dbReference type="OMA" id="ARWWITE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="208"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="377" mass="41376" checksum="48C831FB15FDFC67" modified="2010-04-20" version="1">MNNLTDERFPVTEWDFDDLRLRLYRESDADDVAAAGRDPLARKYLLRLPDPYTTEDALEYIRDVAAGAWTSGRAQWAIADAKTDRVLGGIGVPRIQPAFNSAEIGYVVAPWARGRNIASRATAEVAEFLFRHGVARIELHIMVGNVASQRAAFKAGFTVDGKHRQAIPTREGTQADKWVFSRVPGDPPGPVARAIPDLPDGRLTDGVVTLRRLGPEDVEDHFAHRSLAEVWGRSVPPVEPDRRFTEQICEFGAAEQWLHGANAFMSIRDAQTDAYAGDFGVHVQMGPPGEVMLSYALGRQVRGRGFATRAVRLASAWAIAELGARRVMAGTAADNVASQKVLERAGFTREGVQRALLPGINGTRVDNVCWSLLPEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYL7</accession>
    <name>D3PYL7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3794</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019021.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3794"/>
    <dbReference type="EnsemblBacteria" id="ADD43450">
        <property type="protein sequence ID" value="ADD43450"/>
        <property type="gene ID" value="Snas_3794"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3794"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_891129_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="312" mass="32350" checksum="CC68C63631E73330" modified="2010-04-20" version="1">MIAARVVQGGFGALLFVLMPVLASAAVRPQLRGRAMGWMFAIGPLGAIAGTAAVGVMIDNIGWSSIFLPHLPLAAEGRYAWLAVALLAIPPVLAWRRMESGRLVLSLLRVPGVRAPMTALWTQVTGQLAVSFLVPFYIQRYLDADSALAGLVLLVLPAGMVLFSPLGGWLTDNWGARRTAILGLAVPLAATGSMAWFGETWTIADLAWRLGLLGVGAGLFTGAQTAMAMAAAPADMMGSVSAALSFARQLGLGTAPALATILWGLTGYGLAGMRLAIAVITALGLGGLYALWRARTVAPLPTAPEPARGRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ59</accession>
    <name>D3PZ59_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_5859</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021059.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5859"/>
    <dbReference type="EnsemblBacteria" id="ADD45488">
        <property type="protein sequence ID" value="ADD45488"/>
        <property type="gene ID" value="Snas_5859"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5859"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="PEAKHNT"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="11"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="273"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="344"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD45488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="513" mass="54604" checksum="CA333B93D01B1386" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ92</accession>
    <name>D3PZ92_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha amylase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5893</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021092.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5893"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45521">
        <property type="protein sequence ID" value="ADD45521"/>
        <property type="gene ID" value="Snas_5893"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5893"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_0_1_11"/>
    <dbReference type="OMA" id="YSTARDV"/>
    <dbReference type="OrthoDB" id="1573900at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022567">
        <property type="entry name" value="DUF3459"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11941">
        <property type="entry name" value="DUF3459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="3">
        <location>
            <begin position="12"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="507" mass="56717" checksum="129F4ECA0B7ACB5E" modified="2010-04-20" version="1">MSQWWRDAVIYQVYPRSFADSNGDGMGDMPGIREKLPYLAKLGVDAVWLSPFYTSPMHDGGYDVADFRDVDPMFGGLADFDRMVTEAHRLGLRVIVDIVPNHCSTEHEWFKAALAAGPGSPERERFHFRDSPDGPPNNWPSIFGGPAWTQVPDGQWYLHLFDSSQPDFNWDNPEIHAEFLDVLKFWLDRGVDGFRIDVAHGMVKEPGLPDLPEDKATELLGGSRTPYLDVDGVHEIYRAWRQVLNSYEGDRMAVAEAWVETPERRARYVRGDELHQAFNFDLLKSDFSATEYRKVIDAEMSMANSVGAVPTWVLSNHDRYRHVTRFGDGPLGLARARAATLTMLALPGSSYLYQGEELGLPEVLDLPEDVLQDPVWERSGHTDRGRDGCRVPLPWKRSGPSFGFGPGDSWLPQPGDWGSLSAEAQDGTEGSTLEFYREALRLRREHRPQALIWSEGANGDVLAFSNGALRCVTNFGDSPIRLDGEVLLSSSPLVDGQLPGNAAAWIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZD5</accession>
    <name>D3PZD5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1913</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1913"/>
    <dbReference type="EnsemblBacteria" id="ADD41609">
        <property type="protein sequence ID" value="ADD41609"/>
        <property type="gene ID" value="Snas_1913"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1913"/>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_5_11"/>
    <dbReference type="OMA" id="HRIYEMF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="12"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="223" mass="24847" checksum="E11B133D8D53BCDB" modified="2010-04-20" version="1">MTFADLEPIDRESTAGIIARRLRQAIMDGSMPPGTQLGETELAGRFNVSRGPLREAMQRLVSEGLLRSERHRGLFVIDLEPGDVRDVYTARWAIERAAVIEIMAGDREATAALLDETVAAMAMAADHNNPTALSDADLRFHEVLIGASGCKRLVRMARTLLIETRMCLTLLQTTYRRVDERVDEHNQIIKAIRRGDTPTVLKLLENHMEDAVQRLAPGTTLHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZG9</accession>
    <name>D3PZG9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017214.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1947"/>
    <dbReference type="EnsemblBacteria" id="ADD41643">
        <property type="protein sequence ID" value="ADD41643"/>
        <property type="gene ID" value="Snas_1947"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1947"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3255">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076095_0_1_11"/>
    <dbReference type="OMA" id="RELMFGP"/>
    <dbReference type="OrthoDB" id="1919329at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029229">
        <property type="entry name" value="Alkyl_sulf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14864">
        <property type="entry name" value="Alkyl_sulf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="219" mass="24133" checksum="44B8F6AAB4F4DFE4" modified="2010-04-20" version="1">MATMRSYQDGCAAAHALDIVGERWALLVVRELVLGPKRFTDLRTGLPKASPNVLSQRLRELEHSGVVRKRKLPPPAASQVYELTEWGAELEPILSALGRWGVRSPTMPFTTEIGTDSLIIALRTMFVPDKATTAAIQLWFGHDHFRALIESGSFEIERGEFDEADATVETDAETLKHVALGKSPVDSAIDDGKMTIYGDRGAVERFFARFQLPVAIKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZI0</accession>
    <name>D3PZI0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alkyl hydroperoxide reductase C</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Peroxiredoxin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_1958</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017225.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1958"/>
    <dbReference type="EnsemblBacteria" id="ADD41654">
        <property type="protein sequence ID" value="ADD41654"/>
        <property type="gene ID" value="Snas_1958"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1958"/>
    <dbReference type="eggNOG" id="COG0450">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_21_3_11"/>
    <dbReference type="OMA" id="WWPKDFT"/>
    <dbReference type="OrthoDB" id="892697at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017559">
        <property type="entry name" value="AhpC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF121">
        <property type="entry name" value="PTHR10681:SF121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="2"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="7">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD41654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="183" mass="20544" checksum="0F7619DAE9D9E7AA" modified="2010-04-20" version="1">MLTVGEKFPEYELTACVSLEPENAFDTINHKTYEGQWRVLFSWPKDFTFVCPTEIAEFGRLTGEFADRDAQVLGWSVDSEFVHYAWRKDHPDLRELPFPMLSDIRRELTEAAGVLGEDGVAQRATFIVDPDNVIQFVMVTAGSVGRNVAEVLRVLDALQTDELCPCNWNKGGDTLDATKLLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZI1</accession>
    <name>D3PZI1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1959"/>
    <dbReference type="EnsemblBacteria" id="ADD41655">
        <property type="protein sequence ID" value="ADD41655"/>
        <property type="gene ID" value="Snas_1959"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1959"/>
    <dbReference type="eggNOG" id="COG2050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089876_4_1_11"/>
    <dbReference type="OMA" id="NFAPWVL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="59"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="139" mass="14660" checksum="C27008162DB20883" modified="2010-04-20" version="1">MSVVTLSIDDGNKILRDNFAPWVQDLGLEVVALGDASATLRLPHSPRLNREGGALCGQAMMAAADTATVIAISSASGGFRPMTTVQQSTTFRRPVLDGDVTVVARIGKLGRTMAFVDIDIRDEARTVVAQASTVYAILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZN6</accession>
    <name>D3PZN6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3918</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3918"/>
    <dbReference type="EnsemblBacteria" id="ADD43573">
        <property type="protein sequence ID" value="ADD43573"/>
        <property type="gene ID" value="Snas_3918"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3918"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="WVVNGYN"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="14"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="462"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="502" mass="50797" checksum="813DCB0A81E730DF" modified="2010-04-20" version="1">MAVSVPVVPRRSLVLAIILLSTLTFPLTITGASLALPDIQSDLDSGLAATQWVVNGYNASFAGFLVLTGSLADVFGRRRVFAAGVALFCVTGLTAAVLDDIALLNAVRVLGGIGAAAAVSAAGSILAVTFSGPARARAFGLLGTVLGAGLAFGPTIGGLLVSALGWRGVFLVPGAFAAVVLSLTWLLPKASGAPGRRVDWAGGVLFTTALLLLITVMVQGPEWGFGSPLIIAGFAAAAMLAVAFTLVERRQPDPMFDLGLLVNPQFRSCVIAAGAIVVVLVPLLVYLPSYLIAVVELDAGAAGIWLLMLTVPTVVLPTVGAALSKRMPTVVLMAGSVAVTGAGCLLLVTIGPDSTPLGLLGPLALIGSGFGLSTGLLDGMAITSVPVRQSGMASGIFNSSRLASETVGIAAVGAVLAALSGGRLSGPSYTSALHTVCLALGAFAAAATVLLIVLSLRTTRRREPPWPRDAPRPAGPSHRPASDQPASLGQEPDPWVAPTARY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZV4</accession>
    <name>D3PZV4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3989</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019212.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3989"/>
    <dbReference type="EnsemblBacteria" id="ADD43641">
        <property type="protein sequence ID" value="ADD43641"/>
        <property type="gene ID" value="Snas_3989"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3989"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1672">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="15"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="BTAD" evidence="4">
        <location>
            <begin position="95"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="794"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1003" mass="109859" checksum="C1BE1586D3F5A1D4" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q084</accession>
    <name>D3Q084_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5987</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5987"/>
    <dbReference type="EnsemblBacteria" id="ADD45613">
        <property type="protein sequence ID" value="ADD45613"/>
        <property type="gene ID" value="Snas_5987"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5987"/>
    <dbReference type="eggNOG" id="ENOG502ZNQN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1739422_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="150" mass="15844" checksum="4F0FB8C0CE8B7CE8" modified="2010-04-20" version="1">MTDSGWATPGATAPGRGQYAQVGRPQPQQRPPLLPQSQPQWGRPARPVDETLTRPTYREPHRSTSAGVFAGAGVAVLWFVITAFLGTDLPSRLWVMLAASLVAAGAAFLLARYGDRGAAAGVAAVSGAAVAVVGLVVELQHLLYETWVLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0B0</accession>
    <name>D3Q0B0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction protein with EFhand domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015345.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0052"/>
    <dbReference type="EnsemblBacteria" id="ADD39774">
        <property type="protein sequence ID" value="ADD39774"/>
        <property type="gene ID" value="Snas_0052"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0052"/>
    <dbReference type="eggNOG" id="COG5126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096804_0_1_11"/>
    <dbReference type="OMA" id="IDENEFC"/>
    <dbReference type="OrthoDB" id="1913389at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="6"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="57"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="100"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="186" mass="20888" checksum="68002D6ADFB41F02" modified="2010-04-20" version="1">MVVSEFQRRKLLRRFDTLDVNGSGYLELGDYLRITSRLSRAFPVAARDERVVALVAAYRRLWRELLTEGDSDGDHRVSRDEFVTLMGRELIDSPDNFDRLLRPTIEAVFDICDVDADGVVDAGELRMMLEGYGVPDSAVDVAVARIAPDGTTLDRDAFVSTMRQYYCGDDPAEPGSWMFGKLAPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0G6</accession>
    <name>D3Q0G6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2007"/>
    <dbReference type="EnsemblBacteria" id="ADD41702">
        <property type="protein sequence ID" value="ADD41702"/>
        <property type="gene ID" value="Snas_2007"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2007"/>
    <dbReference type="eggNOG" id="COG1746">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080937_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05400">
        <property type="entry name" value="NT_2-5OAS_ClassI-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006116">
        <property type="entry name" value="NT_2-5OAS_ClassI-CCAase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="33985" checksum="AD5C3FCBA8C29717" modified="2010-04-20" version="1">MTLEQKLSGWTAPSSVTEKEKQDRTERLIKRAMEKHEPLSESKWRVFAKGSYANNTNVKLDSDVDIAVECTDCFYSDGDSGESDDTGPYSGIWTPSKFRTEVQAALEAEFAGRVDCSGSTAFRVNPNSSSVDADVVPCFSYRYYYSPGNFREGTKVFKKDGSSLVNYPKQQLDIGRDKNNRTGHAYKKAVRIMKRVENAMVEEDKYKEVPSYLVECLVYNCPDDVLLRSTWVDTIRGVIAHIYNELGGEEPFDDSLRWCEPNDIKYLFHHSQPWGRNDGRRFARGFADAAWDYLGYEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q140</accession>
    <name>D3Q140_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4139</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4139"/>
    <dbReference type="EnsemblBacteria" id="ADD43790">
        <property type="protein sequence ID" value="ADD43790"/>
        <property type="gene ID" value="Snas_4139"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4139"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="17"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="BTAD" evidence="5">
        <location>
            <begin position="94"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="829"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="983" mass="108151" checksum="4D44DFE3A8A7650C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q189</accession>
    <name>D3Q189_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6045"/>
    <dbReference type="EnsemblBacteria" id="ADD45669">
        <property type="protein sequence ID" value="ADD45669"/>
        <property type="gene ID" value="Snas_6045"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6045"/>
    <dbReference type="HOGENOM" id="CLU_121293_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="167" mass="18379" checksum="7E1B1C69CB4E0283" modified="2010-04-20" version="1">MTSPADKYRRLDNLAVEGSSPDGLLRLVIRQGPSVTLSVRSAAIRDYDARRFEGQFTALLGPSFAAYFEARREIRGAKARAADDLRANGSSRRGWLRLGSRGLVTWRCVLADNAMDALDGAELIAEAQTAVDAVLADYASGLARLRRQRFRHDTWLRVSPAAPRCST</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1E2</accession>
    <name>D3Q1E2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ErfK/YbiS/YcfS/YnhG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_6098</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6098"/>
    <dbReference type="EnsemblBacteria" id="ADD45722">
        <property type="protein sequence ID" value="ADD45722"/>
        <property type="gene ID" value="Snas_6098"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6098"/>
    <dbReference type="eggNOG" id="COG1376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056729_1_0_11"/>
    <dbReference type="OMA" id="DGGQAFH"/>
    <dbReference type="OrthoDB" id="975147at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049446" evidence="4">
        <location>
            <begin position="27"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="5">
        <location>
            <begin position="146"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="24"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="264" mass="29089" checksum="25FABFE4F5965A49" modified="2010-04-20" version="1">MRIRRAFVTIVAVSVALTAMTSGAYASSPDKGTETEQVTTTEKATVSPPSFEQAMNERAKPNPNHNCGETGPKQKQVETLLASLGGYGTVYVDGKQSVEDCAAIKKFQKRMGIKPVAGYAGPVTYGVAKRIADSSLSKCKHSTKRETVCIDLTHQTLWILNKSGKRILGPTVVRTGMKGYATTPGTHKINVREYKHWSKPYKVWLYYWQHFHDGEGLHETTTYIHDASIGSHGCANLLPSDAKKAYDLLSYNDYIKVFGKRPGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1N7</accession>
    <name>D3Q1N7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0165</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015456.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0165"/>
    <dbReference type="EnsemblBacteria" id="ADD39885">
        <property type="protein sequence ID" value="ADD39885"/>
        <property type="gene ID" value="Snas_0165"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0165"/>
    <dbReference type="eggNOG" id="COG1141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_6_0_11"/>
    <dbReference type="OMA" id="GAGMCVM"/>
    <dbReference type="OrthoDB" id="1873445at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001080">
        <property type="entry name" value="3Fe4S_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010693">
        <property type="entry name" value="Divergent_4Fe-4S_mono-cluster"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06902">
        <property type="entry name" value="Fer4_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00352">
        <property type="entry name" value="3FE4SFRDOXIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 4" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Fer4_19" evidence="5">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="65" mass="6895" checksum="4F5B06F54B748352" modified="2010-04-20" version="1">MKIKADREVCVGAGMCVLTAAELFDQDDDEGRVLVLQPEPHPDQVAAAREAVELCPSGALSLEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1R8</accession>
    <name>D3Q1R8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015487.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0197"/>
    <dbReference type="EnsemblBacteria" id="ADD39916">
        <property type="protein sequence ID" value="ADD39916"/>
        <property type="gene ID" value="Snas_0197"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0197"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033093_0_0_11"/>
    <dbReference type="OMA" id="VMNEFSY"/>
    <dbReference type="OrthoDB" id="548749at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021889">
        <property type="entry name" value="DUF3500"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37489">
        <property type="entry name" value="PTHR37489"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12006">
        <property type="entry name" value="DUF3500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="308" mass="34539" checksum="3844EE9CEB47C46C" modified="2010-04-20" version="1">MRQAARRLREALTDEQADAAFHPFADADRTRWDYRPRPRPGACIGEFGLTGRKRAHQLLATAMSPHAFAQITTIMGLEEVLDRAESWRRGRHSDDFWIAVFGSPEDEAWAWRFEGHHVSVSMTVVAEEVSPTPVFLGANPASVDYRGTPVVRPLAIEEELARDLLARLPDRQRAQAIVSPVAPSDIRTGNARDITDIDRWPGLRAADLSRGNAEILDRLIDVYLDRLPPSLAAAERAVIEPDAIHFAWEGSAERGGGHYYRLQSPRLLIEYDNTQNDANHVHTVLRRPGDDFGRGLLPSHVASEREPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q206</accession>
    <name>D3Q206_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsP</name>
        <name evidence="5" type="ordered locus">Snas_2181</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017444.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2181"/>
    <dbReference type="EnsemblBacteria" id="ADD41873">
        <property type="protein sequence ID" value="ADD41873"/>
        <property type="gene ID" value="Snas_2181"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2181"/>
    <dbReference type="eggNOG" id="COG0228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100590_1_1_11"/>
    <dbReference type="OMA" id="FDRALYW"/>
    <dbReference type="OrthoDB" id="1937072at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_S16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_S16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="PTHR12919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="SSF54565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="114"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="18713" checksum="0D46F26F04E96B0F" modified="2010-04-20" version="1">MAVKIRLLRMGKIRQPQYRIVVADSRTKRDGRAIEYVGIYHPKEEPSRIEVKSDRVQYWLGVGAQPSDPVRAILSKTGDWQKFKGLPAPEPLKVAAPKRDKNALYEAEAKSIEVEETKTETPKKKSGAKKTETAKSSKSEAKTETKAAEAKDDKVAEAETTTETAKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q243</accession>
    <name>D3Q243_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41910">
        <property type="protein sequence ID" value="ADD41910"/>
        <property type="gene ID" value="Snas_2220"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2220"/>
    <dbReference type="eggNOG" id="ENOG5033G7X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2540948_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="83" mass="9137" checksum="82B1B8DD277941D6" modified="2010-04-20" version="1">MGWIKNNKVAMMRGDAGKARAEGRMVFACKLNYPALKPDLSGEIVDWSMMIEAVESEGWTLVNFAGGSDKQGRPEALCLFRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2G1</accession>
    <name>D3Q2G1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4245"/>
    <dbReference type="EnsemblBacteria" id="ADD43894">
        <property type="protein sequence ID" value="ADD43894"/>
        <property type="gene ID" value="Snas_4245"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4245"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033540_0_1_11"/>
    <dbReference type="OMA" id="QSGHPDW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="397" mass="42454" checksum="67B44BBFEF23F568" modified="2010-04-20" version="1">MADTTPGKVIRGGRQRRRMTQAALAESAGVSIDLVRKLEQGQRNSARIDSLMAIANALDMPVGDLIGKPRGLTVGAENGEVLHLRRAILGITPHSGEPPSLADLRAQLGELWDMYWHGRYAVLARSLPGHITAARALAHSASGTVARHAHTGIAEALQLTASLLTHLAHEDLAQLALTHATAAADAADDPLLVASMQATRTWVLTRQGLWSEAETIAATTADEVEPKLSTGTVDQLAVWGELLRYTALSLTRAGRHTEATDAQQLLDAAAARMGSDRASKYTGIAFGPTVAAMRAVDAAVAADKPRHALDLARRVTTPDAVPPAMHARYLLTVAYAQTLDWRNTDAVNTIRHAESITPELLPHQTLARVLVAELLPRRRTQRLPGLVPLAQRIGVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2S4</accession>
    <name>D3Q2S4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6202</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6202"/>
    <dbReference type="EnsemblBacteria" id="ADD45825">
        <property type="protein sequence ID" value="ADD45825"/>
        <property type="gene ID" value="Snas_6202"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6202"/>
    <dbReference type="HOGENOM" id="CLU_110577_0_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015068">
        <property type="entry name" value="DUF1877"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035944">
        <property type="entry name" value="YfbM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08974">
        <property type="entry name" value="DUF1877"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111069">
        <property type="entry name" value="SSF111069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="161" mass="18265" checksum="642BAC81CE06D180" modified="2010-04-20" version="1">MGMYVTFVRMTPDELDKAENDPDWAEQFLEDFYDYDGTPPPENSEVDIQKSWAGLDHLLDEAMLPFSIQEGGYCIANGNGWYLNLWTVADLADAAKFLAETPFDTLAAHYDAEAMSREEVYPNARCWDADDLQYLRRDYDDLRAFFIAAADSGHGAMMSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2U1</accession>
    <name>D3Q2U1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flavohemoprotein</fullName>
            <ecNumber evidence="6">1.14.12.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Flavohemoglobin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Hemoglobin-like protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Nitric oxide dioxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ordered locus">Snas_6221</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NADH + 2 nitric oxide + 2 O2 = H(+) + NAD(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19469"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>NADPH + 2 nitric oxide + 2 O2 = H(+) + NADP(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the globin family. Two-domain flavohemoproteins subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.14.12.17" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021413.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6221"/>
    <dbReference type="EnsemblBacteria" id="ADD45842">
        <property type="protein sequence ID" value="ADD45842"/>
        <property type="gene ID" value="Snas_6221"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6221"/>
    <dbReference type="eggNOG" id="COG1017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026437_2_1_11"/>
    <dbReference type="OMA" id="EPYPYRA"/>
    <dbReference type="OrthoDB" id="1834577at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008941">
        <property type="term" value="F:nitric oxide dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051409">
        <property type="term" value="P:response to nitrosative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023950">
        <property type="entry name" value="Hmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396:SF3">
        <property type="entry name" value="PTHR43396:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="17" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GLOBIN" evidence="18">
        <location>
            <begin position="7"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="19">
        <location>
            <begin position="137"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00033187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ADD45842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="368" mass="40025" checksum="D407B38166C24E25" modified="2010-04-20" version="1">MVDADRLKANWELVASHGGQVPLFFYSTLFLTHPETRQLFPVSMAGQRDKLVRALGAVVSSVDDLDAVVPYLKQLGRDHRKFGAVRDHYPAVGAALLATLEHFSGPRWDQALAKDWGDAYGLVAQVMADAADAESSPAWWDADVVAHDRRDLETAVLTIKPRQPLPYRAGQSVTVTSPHRPRVWRHYSPANAPRPDGTIDLHVRMAEAGDVSTALVDLTAPGDVLRLGPPVGDGLRLDETSDRRLLLLAGGTGLAPLKAIVDQVASTRPRPVTLYWGARTTAQLYDLDQLRAMAARHDWFELSACVEEPARGLLTGNPVDLSVRHGHVVGSEVYVCGPTAMVVSARKVLVEAGVDTGSIHYETYGSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q358</accession>
    <name>D3Q358_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0310"/>
    <dbReference type="EnsemblBacteria" id="ADD40028">
        <property type="protein sequence ID" value="ADD40028"/>
        <property type="gene ID" value="Snas_0310"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0310"/>
    <dbReference type="HOGENOM" id="CLU_3317348_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049503" evidence="1">
        <location>
            <begin position="31"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="39" mass="3740" checksum="7AD299525837FD5B" modified="2010-04-20" version="1">MKKLTRILGGLAIGAAALTTSLAAASPAQAADTEAKLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q383</accession>
    <name>D3Q383_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015624.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0335"/>
    <dbReference type="EnsemblBacteria" id="ADD40053">
        <property type="protein sequence ID" value="ADD40053"/>
        <property type="gene ID" value="Snas_0335"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0335"/>
    <dbReference type="HOGENOM" id="CLU_1915808_0_0_11"/>
    <dbReference type="OrthoDB" id="972769at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="132" mass="14412" checksum="543E79A1F2F7ABA5" modified="2010-04-20" version="1">MSKRIDPNRMPDQNLVDALFLCTGGLGSQAAVNLLVEHGHFLSRTDFRRDCLDVTEDEGEQFASVDWNRAAEVSFPCSNSERSILLIAASLATSDIKVNLRDVITGLDTFNTRRVLVAIAHAAGKDGLVNQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3B3</accession>
    <name>D3Q3B3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2265</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017525.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2265"/>
    <dbReference type="EnsemblBacteria" id="ADD41954">
        <property type="protein sequence ID" value="ADD41954"/>
        <property type="gene ID" value="Snas_2265"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2265"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_12_4_11"/>
    <dbReference type="OMA" id="IHAENWL"/>
    <dbReference type="OrthoDB" id="1746871at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006061">
        <property type="entry name" value="SBP_1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01037">
        <property type="entry name" value="SBP_BACTERIAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049506" evidence="4">
        <location>
            <begin position="31"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="418" mass="46755" checksum="35C5710D1D1D61DC" modified="2010-04-20" version="1">MRPRKIVIGFMAAISVLTLASCGGSKDDGAKTGTLNFYTNKAAWEPDFDELNSQSKGDVDIKLNTTGYSDAEQYDAFIKQSFRTKKSPGLFTWQTGPSLGELVDDDLVAETTDIWDKAIDEGWIDKSLRDAYTYEGKQYCVPMNIAYWVMYYNKNIFEKHDLSEPTTWAELDEIAKKLSDEGVTPYYQTSTLFTFPWFQQLVAGTDPELYEGLATGKVKYTDPKIVEIMETWRDQQKDGWFSDAGSKVDPAVGLKDGDFAMINFGSFFNGSLDGAGMKSGEDYDMFVIPAVNSDLKKTPVAVESGPLCVAENSSQKTLGLEYSKWWMSPDAQTAWNKARGDVAFNPKAKVADPMLEELGDTVGGKDYETYDRYYEATPTPILTVALEQFGAFIANPGDPKPYLEKIQEEADKYWADQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3D2</accession>
    <name>D3Q3D2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1801 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017544.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2284"/>
    <dbReference type="EnsemblBacteria" id="ADD41973">
        <property type="protein sequence ID" value="ADD41973"/>
        <property type="gene ID" value="Snas_2284"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2284"/>
    <dbReference type="eggNOG" id="COG5649">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131962_0_0_11"/>
    <dbReference type="OMA" id="GVPVWEH"/>
    <dbReference type="OrthoDB" id="1278667at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014922">
        <property type="entry name" value="DUF1801"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08818">
        <property type="entry name" value="DUF1801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1801" evidence="1">
        <location>
            <begin position="20"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="131" mass="14841" checksum="CE31908F76C6C98E" modified="2010-04-20" version="1">MTYETDTRVDDYINGLPQWKQDICRKVRELVHAADPEVEETVKFKVRPYFVLQGNVCALLAAKDHVNVFLYDGAIVPDPEGIITHGHDNKTARQIAIREGEPINEKALVAMFRQIIANNRNGGWRRIKAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3U2</accession>
    <name>D3Q3U2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl hydrolase BNR repeat-containing glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4362</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019580.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4362"/>
    <dbReference type="EnsemblBacteria" id="ADD44009">
        <property type="protein sequence ID" value="ADD44009"/>
        <property type="gene ID" value="Snas_4362"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4362"/>
    <dbReference type="eggNOG" id="COG4447">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058803_2_0_11"/>
    <dbReference type="OMA" id="GQCVHKI"/>
    <dbReference type="OrthoDB" id="1293876at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="366" mass="39796" checksum="14EA1B5F149A96ED" modified="2010-04-20" version="1">MSYLMAIGTKKGLFTATSDDRVNWDVTGPHRLGGDASTVQTGVYAIGIDTRRDTPRLFVGADSSHFGPSVWHSDDAGATWSEPADAPPIALPEDTDTAFARAWQFGFGPEPDVVFASGEPHSLFKSTDGGVTFELNRGLWDHPHRTEWFPGFGGAAIHTIMPHPTDPAKMSVAMSTGGFYQTEDGGASWNPTCQGIRADFFPEPYPEFGQCVHKAVRAAGDPSRFYLQNHGGVYRSDDGGHKWNSIAEGLPCDFGFAMVAHPHRTDSVLSFPVHADANRFLPDNRLQVHRSDDGGSTWREVSQGLPTEPYFGIVLRDAAATDAAEVPGYYFGTRCGDVFVSTEDSENWVQAASHLPDVLCVRAARM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3X9</accession>
    <name>D3Q3X9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SpoOM family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019617.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4400"/>
    <dbReference type="EnsemblBacteria" id="ADD44046">
        <property type="protein sequence ID" value="ADD44046"/>
        <property type="gene ID" value="Snas_4400"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4400"/>
    <dbReference type="eggNOG" id="COG4326">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057336_0_0_11"/>
    <dbReference type="OrthoDB" id="1033384at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009776">
        <property type="entry name" value="Spore_0_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40053">
        <property type="entry name" value="PTHR40053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07070">
        <property type="entry name" value="Spo0M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="254" mass="27191" checksum="273F3887E3442B8C" modified="2010-04-20" version="1">MVFRIIKAVLGKGVGVDTVLNGTEVTPGGSLSGEVKFNGGEVDAKVEGITLEFTAVVEEDAKGEERKATYHFHRAQVSGGFELAAGTSHAVDFDVPVPWETPLSAFAGRPLPGMTLGVATELALDKAFDKGDLDPLTVEPLPVHVAALNAMDALGLVFQTADLEAGTLPGSHMPFYQEIEYWPGGEFKGSFTEVELTFVTSKSSTDILLQANDQGSPLSAGHDKYQRFTVKNDDTSDLTDVIRTQLEQLAQRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Y4</accession>
    <name>D3Q3Y4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4405</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019622.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4405"/>
    <dbReference type="EnsemblBacteria" id="ADD44051">
        <property type="protein sequence ID" value="ADD44051"/>
        <property type="gene ID" value="Snas_4405"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4405"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_3_2_11"/>
    <dbReference type="OMA" id="YMFCAAF"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="215" mass="22520" checksum="B0DF9AC1E4CB3A08" modified="2010-04-20" version="1">MVSLGAIAGVAAIALGMVLTPGPNMFYLVSRTLNQNRRAGLVSLTGMAAGFVIYLLATIAGLTAVFALVPAAFFVLKIAGAAYLLYLAWQAFRPGGASPFSPEPSPAQSYTRLFTMGMVTNLLNPKIAIFYVSLLPQFVDPHAGNLVGQSLALGLTQVAIALTVNGLIVVCASGLAGFLKRRPTWMRAQRAVMGTVLAAFAVRMAFDPTRASATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q468</accession>
    <name>D3Q468_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome P450-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021524.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45953">
        <property type="protein sequence ID" value="ADD45953"/>
        <property type="gene ID" value="Snas_6336"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6336"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_0_11"/>
    <dbReference type="OMA" id="WESEWMI"/>
    <dbReference type="OrthoDB" id="816674at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="381" mass="40721" checksum="08CFED8623473399" modified="2010-04-20" version="1">MRDAPFRADIDPFAATVHRLTEPDPVRAALRAAGPLVQVEAPAGGRVWIITTDELARAALADPHFAKDPAHAPDGWDRFTAGLEPTAAEQPALTTLDGPEHTALRRAHAPLLSAKRIAAQSDRVHAIARELLAGLAETTSTVDLMSDFTVRYPITVLLDLLGVPAEFVSRAVGACRRMICTDPAVQGAAIAEIAEIGAEGLSGTGLAAELRERLGEDASDRDLRYHLFALIFAGQLTTDASLGFLVADALRGDRPEPDVDALVRDTLREHPAAPFSLWRFTNADTEIAGFRLPARAPVLIDIMGINTDPDRAPGPDLTFGGGAHFCVGAQLAQLELRAVATVLRTDYPQARLAVPYEELRQLSPGGIQGIRLAALPILLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q477</accession>
    <name>D3Q477_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6345"/>
    <dbReference type="EnsemblBacteria" id="ADD45962">
        <property type="protein sequence ID" value="ADD45962"/>
        <property type="gene ID" value="Snas_6345"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6345"/>
    <dbReference type="HOGENOM" id="CLU_3205539_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048648" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="45" mass="4565" checksum="8B588F8CD55F8039" modified="2010-04-20" version="1">MTLRRSLVAAALALAGLLTVSAPAIASLSDSGTTMADNCHCRKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q493</accession>
    <name>D3Q493_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transketolase central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6362"/>
    <dbReference type="EnsemblBacteria" id="ADD45978">
        <property type="protein sequence ID" value="ADD45978"/>
        <property type="gene ID" value="Snas_6362"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6362"/>
    <dbReference type="eggNOG" id="COG3958">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009227_1_1_11"/>
    <dbReference type="OMA" id="KVDVCYN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="1">
        <location>
            <begin position="9"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="307" mass="32681" checksum="9338FB884E49A9C9" modified="2010-04-20" version="1">MNATVAEAIAMRDVFISETARLLDDNPRLALVLADISAGEGRFAQAGVDHPDRVINVGIREQLMVGVAGGLALAGLRPIAHSYAPFLVERAFEQVKLDFGHQGTSGILVSVGASYDWSEGGYTHFSPRDVALFDTIPGWTVHVPGHPDEVTGPLRAAADSDESVYIRLSNRRNAEAHASPDGKLTVLKRGGQATVVAVGPMLDNVLAATADLDVTIAYAATVRPFDTQTLRELAGTTADTIALVEPYLAGTSDHIVNAALTDRPHRLLSLGVGREDLHRFGTPDDHDSWHGLDPAGIRASLSKFLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4L9</accession>
    <name>D3Q4L9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TAP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0464</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015750.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0464"/>
    <dbReference type="EnsemblBacteria" id="ADD40179">
        <property type="protein sequence ID" value="ADD40179"/>
        <property type="gene ID" value="Snas_0464"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0464"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_3_1_11"/>
    <dbReference type="OMA" id="QTYYYES"/>
    <dbReference type="OrthoDB" id="665798at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048659" evidence="2">
        <location>
            <begin position="29"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="83"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="499" mass="54329" checksum="E1D85542EF728604" modified="2010-04-20" version="1">MRSRYLWAAAVAVVVASAVTVVSVTANAEDGRGSVDWKPCPDDEKVKCASITVPLDWSNPDGEEIDIALAMQPATEPESRIGSILMNPGGPGGSGVDKVASGLPIVGEEVAKRFDVVGFDPRGVNKSTPIKCDAALAEEANKMAMPTNQDEFDKVADVNRRLAEDCRERTGPLFDHVDNLSVVEDMDAIRSALGEEKLNFLGYSYGTLMGQQYAEKYGDRIRTMVLDSNMDHSLATPGEYMETGTAAFEENFVAFADWCDTTKDCALNGDGTRDVYAKLRESAKAGELTDPKTGDPIDFEALSLIAFAANNPEMWDKLDDQLKALRDHKPSATEKLAEPEEVNEPFQPIWCQDWDYQVKDFEDWRSLNADVAERHPNVESSPYNRNLLSCVGYPGETTNPQRPLEIDDAPSMLMVGSRHDPSTPYPWSTTAARQSGASLVTYEGYGHGLYGFAGDSDCVNKAVESYLIDQTTPADDLTCPADGKSRTTTGLTDGSPGPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4M2</accession>
    <name>D3Q4M2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015753.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0467"/>
    <dbReference type="EnsemblBacteria" id="ADD40182">
        <property type="protein sequence ID" value="ADD40182"/>
        <property type="gene ID" value="Snas_0467"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0467"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_2_3_11"/>
    <dbReference type="OMA" id="QSNIRYQ"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="381" mass="41314" checksum="D9BF2E0C4835207A" modified="2010-04-20" version="1">MADDRYDRIQAALDRVVADGSAPSAVAHLKDGDGTWFGSAGVADLETGRRRDPKDRFQVGSIGKAFTATALLTLEAEGVLNLDDTVDTWLPGVIRGNGNDGTRMTLRQLLSNTSGLGTTGLSPEIVRRYHTRSGFAENRYHVWTVDELIRVQLDIPAVFAPGEGFSYANGGFQIAGAVIEKATGRSYQQEIDRTVIQPLGLPDTYTQDLSESRFRGQHCKAYSKGLFIRDDVDPDILTAENYQSLLEEPAGDPLDITERTYFEGAAGCVVSTTGDLLTVAEALITGSLLPTDQHRAMWTTVATANWLPNARYGLGVSQWRLADGRQLHVMSGMTGGTACLALGTPDGETVLATHVNGDWNWYLAFYQIAEAVFGSPFDVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4R2</accession>
    <name>D3Q4R2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2409</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2409"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42092">
        <property type="protein sequence ID" value="ADD42092"/>
        <property type="gene ID" value="Snas_2409"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2409"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015079_0_0_11"/>
    <dbReference type="OMA" id="AYLINDM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="30"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="219"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="660" mass="71670" checksum="EFC547E25A7B1C5A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4U9</accession>
    <name>D3Q4U9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Cysteine desulfurase</fullName>
            <ecNumber evidence="4 6">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2446</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4 6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017700.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2446"/>
    <dbReference type="EnsemblBacteria" id="ADD42129">
        <property type="protein sequence ID" value="ADD42129"/>
        <property type="gene ID" value="Snas_2446"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2446"/>
    <dbReference type="eggNOG" id="COG0520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_5_11"/>
    <dbReference type="OMA" id="HKLCGPT"/>
    <dbReference type="OrthoDB" id="446447at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01979">
        <property type="entry name" value="sufS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="7">
        <location>
            <begin position="36"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="429" mass="45931" checksum="A2B9AF3CD49810D5" modified="2010-04-20" version="1">MSAVSARPEGVPDLDVDKIRADFPILSRQVNGKPLVYLDSGNTSQKPRAVIDAMSSFAEQHNANIARAVHTLGTESTTAYEGARAKVASFIGAPSVDEVVFAKNSTEAINLVAYSMLAASLERGGDPRFKLGPGDEVVISEMEHHSNIVPWQLLCERTGATLKWFGITDAGRLDESNLEELVTERTKIVSYVHMSNILGTVNPVARISQRAREVGALVMLDCSQSVPHLPVNVADLGVDFIAFTGHKMCGPTGIGVLWGKGELLSVMPPFLGGGSMIGTVTMEKSTFAAPPARFEAGTPPIIEAVGLGAAVDYLSNLDMRAVQWHEKELTAYALPKLETVPGLRIIGPRVPVGRGGCISFHMEGIHPHDVGQVLDSEGVQARVGHHCAKPVCARFGIPAATRVSFYVYTTQDEIDALVAGLEKTRKVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Z3</accession>
    <name>D3Q4Z3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane-flanked domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017744.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42173">
        <property type="protein sequence ID" value="ADD42173"/>
        <property type="gene ID" value="Snas_2490"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2490"/>
    <dbReference type="eggNOG" id="COG3428">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024617_4_2_11"/>
    <dbReference type="OMA" id="FRRTAHI"/>
    <dbReference type="OrthoDB" id="602555at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014529">
        <property type="entry name" value="UCP026631"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026631">
        <property type="entry name" value="UCP026631"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="60"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="247"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="367"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="449" mass="48423" checksum="DA34049E53E3B181" modified="2010-04-20" version="1">MSTGKQRLHPLSPVLNGIKSLGVVMAAISWQGFAQFGVTTGGMIVAAGGVLGLIWAWIAWRFTGFEIADRELRISEGALMRRHRTIPLQRLQSVEVVQPLLARPVGLAQLRCEVVGAAKTEAPLSFLTLKDATELRERLLTLSKQSATASSVATDDATDPDATAEPTVVDTAPVEEATPVLTVPSGLLLRSQLLTPQVFALPFAVAVTVVFFVVNPDATFFGIAALISALLGILLSPVRQAMGNYDFTLTETDTELLIRRGLTERRTQTLPHERVTAVTIQRPLLWRWAGWVTCRVANAGGGSSGSEQLLGGTLLPVGTHEQARTVTTHALSGVDLTAVRLIGVPRRARWRSPIGQPALGAGLGEQVFVCRRGRVIPQLVAVPYARIQSVRVTQGRWQRALRLATVSVDIAGGIGINPRASHRDLDEALDMALRLRERSREAARPQPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q512</accession>
    <name>D3Q512_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4415"/>
    <dbReference type="EnsemblBacteria" id="ADD44061">
        <property type="protein sequence ID" value="ADD44061"/>
        <property type="gene ID" value="Snas_4415"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4415"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055817_1_3_11"/>
    <dbReference type="OMA" id="AKMERGW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043917">
        <property type="entry name" value="DUF5753"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19054">
        <property type="entry name" value="DUF5753"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="18"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="283" mass="31593" checksum="0473BE7C69F0097E" modified="2010-04-20" version="1">MASGRKPTIRAVWLGQELRKMRDEAGLTVRAMGSLVHLNQANVSKLENGIYPASVQHVEAYLRICGIDDPKRRSDVFKICDDVLRKGWWDGFAGELASELMDRIWLESKAVHIDAFEPILVPGLLQTSAYARAVMAADQPDASSERLERWHDVRTTRQLIITKHEPITLRAIIDQSVIRRAISDSEAGLPQLRFLAEVSERPNIELRVLPDSAGFHAGMNGSFEVLSLADPYPEAGLLTTPSGEVCVEGDAIHHLKQKYELLLQSSLDPEPSRKLIKSEVDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q580</accession>
    <name>D3Q580_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BAAT/Acyl-CoA thioester hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019700.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4484"/>
    <dbReference type="EnsemblBacteria" id="ADD44129">
        <property type="protein sequence ID" value="ADD44129"/>
        <property type="gene ID" value="Snas_4484"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4484"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_572249_0_0_11"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="171"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="477" mass="51040" checksum="EEED5184047C152A" modified="2010-04-20" version="1">MTKAKLGWVALLPGQDGLIRINLPADAKQATFDLPARLQFGRELHPVLPFDIEAWRSRVGEYTDGDIKLVVTMNPDSGLAEPFPFYVDLDHDAVVPLTPIAADRLLSEQGEEITFTADGELRIAIEGAEATLRRAEVPVEEEVSFLVSGEATVVAGTLLRPAGEGPFPAAVLVHGSSFHQRDFYRMWAHALVRAGVAALIFDRQGHGASTGEVAETLQDRAAGVEAAMNFLKEHKAVSEVGLWGISNGMWTVPLVAARRPDVAFVAGVSAPGVTAAESEAHRRGTALRQGGVSAEAAGIAEKIWRLLAEVSQTGDASPSQVRKLEPLLKKLRADKTVKAYTPPGYAKTSPKLSPMPPSGSAAEVAKAHAGTPDPSVGYDPANSYREISCPVLLQYGTDDPNLPAAESEKRIRDALTDGGNENFTITSYPNAGHLLERVPSEVDGMTHEEASYGLHGLRFASGAVSEFISWFEARKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5A9</accession>
    <name>D3Q5A9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4513</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019729.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4513"/>
    <dbReference type="EnsemblBacteria" id="ADD44158">
        <property type="protein sequence ID" value="ADD44158"/>
        <property type="gene ID" value="Snas_4513"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4513"/>
    <dbReference type="eggNOG" id="COG1120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_11"/>
    <dbReference type="OMA" id="MVLHDLQ"/>
    <dbReference type="OrthoDB" id="1048863at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="258" mass="27187" checksum="E4912DE3EA401B1A" modified="2010-04-20" version="1">MKLSVKDLCASYPGVKAVSGVDLEVEPGTVVAIVGPNGCGKSTLLRSVARLHKPDSGSVTVDGDEVWSLRPRAAATRLALLPQSPIAPEAITVAGLVAYGRHPHQGLFRQWSRADAEAADRALAATGVAELANRRLETLSGGQRQRCWLAMTLAQETPILLLDEPTSALDLGHAVETLHVIRQVAARGRSVVMVLHDLGAAARYADVLVAIKDGEVVANGDPRVVVTSELVRRLYDVEADILTAPGDGAPVVVPRAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5E3</accession>
    <name>D3Q5E3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase</fullName>
            <ecNumber evidence="9">2.7.8.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_6387</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.6" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6387"/>
    <dbReference type="EnsemblBacteria" id="ADD46003">
        <property type="protein sequence ID" value="ADD46003"/>
        <property type="gene ID" value="Snas_6387"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6387"/>
    <dbReference type="eggNOG" id="COG2148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024920_3_3_11"/>
    <dbReference type="OMA" id="WHRPYTA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047360">
        <property type="term" value="F:undecaprenyl-phosphate galactose phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017475">
        <property type="entry name" value="EPS_sugar_tfrase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03025">
        <property type="entry name" value="EPS_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="8">
        <location>
            <begin position="330"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD46003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="522" mass="57672" checksum="771D21254FF6CD51" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5I7</accession>
    <name>D3Q5I7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin reductase</fullName>
            <ecNumber evidence="3">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_6431</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021618.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6431"/>
    <dbReference type="EnsemblBacteria" id="ADD46047">
        <property type="protein sequence ID" value="ADD46047"/>
        <property type="gene ID" value="Snas_6431"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6431"/>
    <dbReference type="eggNOG" id="COG0492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031864_5_1_11"/>
    <dbReference type="OMA" id="VDNFPGY"/>
    <dbReference type="OrthoDB" id="692968at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="6"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD46047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="32848" checksum="64064698CC1EC08A" modified="2010-04-20" version="1">MSDIRNVIIIGSGPAGYTAALYTARADLKPLVIEGAESGGALMTTTDVENFPGFADGIMGPDLMDTMRKQAERFGAELLTDDVTKVELTGKVKTVWVGDTAYKAHAVILATGSAWRPIGIPGEQELLGHGVSSCATCDGFFFKGQHIAVVGGGDSAMEEATFLTKFAESVTIVHRRDSFRASKIMADRALSNPKIKVEWNTVVDKVVGDQKVTGLEVRDVTTGKTRTLDATGMFVAIGHDPRSALFADQVDTDDEGYVKVDSPSTRTNLAGVFAAGDLVDNTYRQAITASGTGCAAALDAERYVAALETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5P1</accession>
    <name>D3Q5P1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribonuclease P protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_6486</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6486"/>
    <dbReference type="EnsemblBacteria" id="ADD46101">
        <property type="protein sequence ID" value="ADD46101"/>
        <property type="gene ID" value="Snas_6486"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6486"/>
    <dbReference type="eggNOG" id="COG0594">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117179_4_2_11"/>
    <dbReference type="OMA" id="VHFRRET"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000100">
        <property type="entry name" value="RNase_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020539">
        <property type="entry name" value="RNase_P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992">
        <property type="entry name" value="PTHR33992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00825">
        <property type="entry name" value="Ribonuclease_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00188">
        <property type="entry name" value="rnpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00648">
        <property type="entry name" value="RIBONUCLEASE_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD46101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="89" mass="9685" checksum="7359CFBB01DA2F79" modified="2010-04-20" version="1">MVVHLATRDDETARGARAGFIVSKAVGPAVTRNKVKRRLRHLAAPRLAGWPNGTDVVVRALPAAATISFQRLSRDVDEALAILSRSRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5V8</accession>
    <name>D3Q5V8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015828.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0543"/>
    <dbReference type="EnsemblBacteria" id="ADD40257">
        <property type="protein sequence ID" value="ADD40257"/>
        <property type="gene ID" value="Snas_0543"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0543"/>
    <dbReference type="HOGENOM" id="CLU_833965_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="333" mass="34640" checksum="A53C9DDA72A05FDE" modified="2010-04-20" version="1">MSQQPYDPAVTGGFTVADGFSVIPPKRPTAVTLASAIMLAIAGLSGLGALVLIVVEVLDNPDPGSVLQSVRFDLGLWLFLLAVGVAPCALLVRNGSDGGRLATFTLLGIATLSCFGNAMQTLVELSGSIDVAIVAVPLWLLAAALTVTPVVALASPAASRWFWEQRREVSIMDPAVAVPRPTMFTVGVAFVALTALLDIAAKAAYLALMFNTSGIDIATYYLGFFASSAAPLIAVLVATVGLAVRSDLARVLAFGACGFYVYSGLRSQIGLVTNLDMYAIDVWFVVTFALGLLAAVSSTVALVALYRPQVSLWLGQNRFGVEPAGSASGDVHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q669</accession>
    <name>D3Q669_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal_L12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2564"/>
    <dbReference type="EnsemblBacteria" id="ADD42244">
        <property type="protein sequence ID" value="ADD42244"/>
        <property type="gene ID" value="Snas_2564"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2564"/>
    <dbReference type="HOGENOM" id="CLU_167427_0_1_11"/>
    <dbReference type="OMA" id="DPRMERV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal_L12" evidence="1">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="95" mass="10590" checksum="5B8DFAF7A860C391" modified="2010-04-20" version="1">MTMLTILVAITLLTSVLIMNTLSGLVTTNQRHHARVDRKLNQIMEHLGIDTAASELSEVTELALRGKKIQAIKRHRELTGSSLKEAKDAVERMLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6A8</accession>
    <name>D3Q6A8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017854.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2604"/>
    <dbReference type="EnsemblBacteria" id="ADD42283">
        <property type="protein sequence ID" value="ADD42283"/>
        <property type="gene ID" value="Snas_2604"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2604"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1567962_0_0_11"/>
    <dbReference type="OMA" id="LRRWAFQ"/>
    <dbReference type="OrthoDB" id="1467120at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="164" mass="18058" checksum="7A5679962DAE756E" modified="2010-04-20" version="1">MSEFKTPVPNPALDAVAPDVYREIYGMPMFTIVPTADLEASKDFWLDGLGFIDLFSIPGGVTHLRRWAFQDVLLVPGEPPAEAPAQSLNFACVLSQIEEVRQRCEKLVPGCTDGPREMPWNSVELTVITPENARIVMTAARPIDPNSQMAADWRAVGIPIPENP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6M2</accession>
    <name>D3Q6M2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4622</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019836.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4622"/>
    <dbReference type="EnsemblBacteria" id="ADD44265">
        <property type="protein sequence ID" value="ADD44265"/>
        <property type="gene ID" value="Snas_4622"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4622"/>
    <dbReference type="HOGENOM" id="CLU_1757708_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="148" mass="15718" checksum="E3A788A740A03CE3" modified="2010-04-20" version="1">MNDYAGESGGGSSAPQPNIEFEAVEMDTVSLKAFGDALLKDAENLKTAAGDIREQLQNPAGERGDDMIQPVGADPRQETLHGIAITHSQRMQETNVYLAQASIAVNNLGLLCKYIAGSIGDVDTLNSSSIDQVSDVINDVTKPKKEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Z5</accession>
    <name>D3Q6Z5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015965.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40394">
        <property type="protein sequence ID" value="ADD40394"/>
        <property type="gene ID" value="Snas_0681"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0681"/>
    <dbReference type="HOGENOM" id="CLU_2262103_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="103" mass="11350" checksum="8CB93F9501BF5455" modified="2010-04-20" version="1">MSGGVYHISYPAIQQMQNEFNQDAEKVRTEFQNLRNAVQGAAQQGLKGAEGLELESGTLPALDKDWKTLSDELNDISQRLKQTEANARDRASSNAKLLQTSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7A7</accession>
    <name>D3Q7A7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017949.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2701"/>
    <dbReference type="EnsemblBacteria" id="ADD42378">
        <property type="protein sequence ID" value="ADD42378"/>
        <property type="gene ID" value="Snas_2701"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2701"/>
    <dbReference type="eggNOG" id="COG2364">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083843_0_0_11"/>
    <dbReference type="OMA" id="APWDVLH"/>
    <dbReference type="OrthoDB" id="1009891at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038750">
        <property type="entry name" value="YczE/YyaS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40078">
        <property type="entry name" value="PTHR40078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="227" mass="23902" checksum="AD7650D2968BC8C1" modified="2010-04-20" version="1">MTAPAATRRLTTLGPIAQLRAGRLPRRLSQLYIGLVLYGASLALMVRGDLGLSPWDVFHSGLIRHIPLTLGQAVVVMSFVVLLAWIPLREKPGLGTISNAIVIGLAADGVLAILDRPDALYARIGLLVAGVLLNGVATAAYIGSQFGRGPRDGLMIGLHRVTGRSIRLVRTLMEIAVVLAGLALGGVLGVGTVLYALAIGPLSQLMLPWFTVALPGEDATEPEPQRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7J0</accession>
    <name>D3Q7J0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4689</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019903.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4689"/>
    <dbReference type="EnsemblBacteria" id="ADD44332">
        <property type="protein sequence ID" value="ADD44332"/>
        <property type="gene ID" value="Snas_4689"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4689"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_2_3_11"/>
    <dbReference type="OMA" id="HHYANAN"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049625" evidence="1">
        <location>
            <begin position="30"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="41"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="374" mass="40065" checksum="362CE76C7C8A7A6C" modified="2010-04-20" version="1">MRTRTTVAGLVTGAALVAATVFTVGGAHADTVDTDPIQAAMEKLHDAGVHGVIARVDDNDQTWASAVGVADVDSGRPMSPDFEHRIGSITKTVTAVAILRQVEAGNLDLDDPVGDYLPRLLPGERGDKITVRMLLDHTSGINNHVDAMFPDLETSLDTVEKYRYRTWKPEKLARIGLKMEPTGEPGEKKSYSNTNYVIAGLVLEQVTGEDAEEHITREVIDRAGMRDTYFPGRDPSIDGPHSKAYLTIRNGEHGEFSVYNMTWAATAGALVSTADDQAAFAKALMGGRLLGDEQLAAMKDGLGLVSTELGGCEILGTNGAVPGMDSFLAFDETGERSIVIEGNTTDQRPEVADKIGKAYMGLINTAAEETLCDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8A0</accession>
    <name>D3Q8A0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal transduction protein with CBS domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2798</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018045.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2798"/>
    <dbReference type="EnsemblBacteria" id="ADD42474">
        <property type="protein sequence ID" value="ADD42474"/>
        <property type="gene ID" value="Snas_2798"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2798"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040681_12_0_11"/>
    <dbReference type="OMA" id="QWCVEDD"/>
    <dbReference type="OrthoDB" id="2014094at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="74"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="140" mass="14267" checksum="74899E97A142764E" modified="2010-04-20" version="1">MGAQISSVMTPNPVCVPQDASVSATAAIMRDNDIGSVIIMNDGRVSGIVTDRDLVVRGLAEGFNPQEAPVGAVASPSAICLAPDSSTADAVRQMRESSVRRLPVCDSAGHPVGIVSLGDLAEELDPESALADISAATPNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8A5</accession>
    <name>D3Q8A5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">APH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018050.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42479">
        <property type="protein sequence ID" value="ADD42479"/>
        <property type="gene ID" value="Snas_2803"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2803"/>
    <dbReference type="eggNOG" id="COG3173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1260815_0_0_11"/>
    <dbReference type="OMA" id="EAWACRR"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016259">
        <property type="entry name" value="Hygromycin-B_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000707">
        <property type="entry name" value="Hygromycin-B_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="219" mass="23654" checksum="196FC1FF6AF1FDEA" modified="2010-04-20" version="1">MSRLSGTPWRELGADVGRDARVLDQLAEVFAHLHSVRGKGFGPVTDESDDSFGSWAEWLRQGLTVDIGQLLDARVADRGLLELAESALSAVAVELADRPGALVHGDLGDGEVFVDATTGRVTGIADWGAAVIGDPFYDFARFVAGGPVDDARVPRLLPGLRAAYAARTGIDWDDHRRLMDLYDAHNAVNNAAWALREGVDWVASLRAKAERLLQRVVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8G9</accession>
    <name>D3Q8G9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bile acid:sodium symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018114.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2868"/>
    <dbReference type="EnsemblBacteria" id="ADD42543">
        <property type="protein sequence ID" value="ADD42543"/>
        <property type="gene ID" value="Snas_2868"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2868"/>
    <dbReference type="eggNOG" id="COG0385">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034788_0_1_11"/>
    <dbReference type="OMA" id="MEIGIHN"/>
    <dbReference type="OrthoDB" id="1493959at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004710">
        <property type="entry name" value="Bilac:Na_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="PTHR10361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="293" mass="30514" checksum="3CD1C5E22D12534D" modified="2010-04-20" version="1">MDTVLIEVFLPIALAIIMFGLGLGLTTADFARVARYPRAAAAALGCQILLLPAACFGLVLLFELPPVLAVGMMLLAASPGGTTANLYSHLFGGDVALNITLTAINSVVAVVTLPLVTNLALTYFVADGGTLGLQFGKTLQIFAIVLVPVVLGMLVKRRSPGFAARLSRPVKIASAIILVLVIAGAIATEWANLGGYIRSVGAITVLFSVLSLTVGYWVPRLLKVERRQAIASCMEIGIHNSTLAITIALSPALLGNVEMSIPAALYGLVMFFTAAGAGFLARRGVKDEPVKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8K1</accession>
    <name>D3Q8K1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4802</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020014.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4802"/>
    <dbReference type="EnsemblBacteria" id="ADD44443">
        <property type="protein sequence ID" value="ADD44443"/>
        <property type="gene ID" value="Snas_4802"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4802"/>
    <dbReference type="HOGENOM" id="CLU_2289942_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="101" mass="11299" checksum="623259D52ADFA0D0" modified="2010-04-20" version="1">MRFDVSLMRARARNIEKLSETALACARRSEDGLNIENNDGFDTVAEVRTVRGELTELLESISGELKAAAVDLKNFADEVEGVDLDNADELRRFDEEPPMPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8L1</accession>
    <name>D3Q8L1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carboxyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4812</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4812"/>
    <dbReference type="EnsemblBacteria" id="ADD44453">
        <property type="protein sequence ID" value="ADD44453"/>
        <property type="gene ID" value="Snas_4812"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4812"/>
    <dbReference type="eggNOG" id="COG4799">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018822_6_2_11"/>
    <dbReference type="OMA" id="AYDVHPI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="2">
        <location>
            <begin position="224"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="475" mass="49246" checksum="DFC5609B7A9C8B36" modified="2010-04-20" version="1">MSNPTVEAEQEVVDVRDPMPRLTALFDTGTISLLHSGDDSGVVTARGDIAGSPAIAYCSDARVKGGAIGIDGGKHIVDAIDTAVRERIPVIGVWHSGGARLAEGVTALHAIGEIFAAMVRASGRVPQISVVLGPAAGGAAYGPALTDIVIMSNSGRIFVTGPEVVKSVTGEQSDMETLGGPDVHGKKSGVAHITTKDDATAFATARDLASLLGRPGRFEAADADDSTDLGALLPEQANRAYNVKPLVKKLLDSGEGVESPVEMHGKWAASIVTVLGRFAGRTVGVIANNPLKLGGCLNSESAEKSARFVRMCDSLGIPLIVLVDVPGYLPGLGQEWDGVVRRGAKLLHAFAESVVPRVTLVTRKSYGGAYIAMNSRSLGATAVFAWPTAEVAVMGASAAVNVLHRKKLAAVPAEERDALREKLIADHENEAGGVSKAIDIGVVDEVIEPSQTRFRIAQALASAPPARGAHGNIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8N4</accession>
    <name>D3Q8N4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4835</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4835"/>
    <dbReference type="EnsemblBacteria" id="ADD44476">
        <property type="protein sequence ID" value="ADD44476"/>
        <property type="gene ID" value="Snas_4835"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4835"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="RRIPWIT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="213"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="414" mass="44938" checksum="9431589E10FC318D" modified="2010-04-20" version="1">MNRGATLDVGGFCHGDDANALRRWFDRTVETEKRVTVQRALLVAVTVFALGSVIVGFNFHSSTGVQVPQWLRFATLGMVCVALFFRSLAPRVGLLIGTVGFAVDAVIGMSIATMAVYTDNIYSATLRGPRYMPRMLLLFSCLTSVGLSTLVYLAEQFRVAVLVLAVLALIMISPVATGMIVREHRERAELERDRAAKIARLAEVDRRAAVNEERTRMARELHDTIANHLSAIAMRSSAVLAQPNMDAETMRGIVADIRAGSVAGLAEMRGTIELLRRGESEDEVVQHRLSGLEELVTRMKEAGLDVALRVRGNLADLPVAVDFAAYRIIQEALTNVLKHGRDAEVELTFSSTKVSITIDNRLPETASGVPGSGNGLIGMRERATILGGSFSAGPHGAGWRVRAELPSTNDKKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8P4</accession>
    <name>D3Q8P4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4845</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020057.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4845"/>
    <dbReference type="EnsemblBacteria" id="ADD44486">
        <property type="protein sequence ID" value="ADD44486"/>
        <property type="gene ID" value="Snas_4845"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4845"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_873278_0_0_11"/>
    <dbReference type="OMA" id="GEDPNHT"/>
    <dbReference type="OrthoDB" id="1308416at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="3"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="159"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="32646" checksum="A851A36A8F0B584F" modified="2010-04-20" version="1">MLKTTRVSAYGILTDDRGRVLMQRTRANSDVPDSWWLPGGGLDHGEDPADAVVREMREETGLDVEVTALRTVETQLVELGPDWRYHKVSVVYDVKDVGGRLKTEVGELSDDADNVWCDLADLDGKRMIELNAEVLGVRAVPMVRTRPPTRPSPVPDGQVQRVGVYAWVTDPLGRVLMTLIPEGFPMAGLWHLPGGGLDFGERPREALSREIVEETSQDAVLGGLRCVQSIHHAESIGPSGRVEDFHGIHVIYDATVAEPKPLEIQDVGGSTSEVVWLEVDEIRRLPVTPAVEAALALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Q4</accession>
    <name>D3Q8Q4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020067.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4855"/>
    <dbReference type="EnsemblBacteria" id="ADD44496">
        <property type="protein sequence ID" value="ADD44496"/>
        <property type="gene ID" value="Snas_4855"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4855"/>
    <dbReference type="eggNOG" id="ENOG502ZB3I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026633_0_0_11"/>
    <dbReference type="OMA" id="VHWLAPL"/>
    <dbReference type="OrthoDB" id="277707at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="635"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="669" mass="74258" checksum="136D1163D252B3C2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Z7</accession>
    <name>D3Q8Z7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, DeoR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0895</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016177.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0895"/>
    <dbReference type="EnsemblBacteria" id="ADD40606">
        <property type="protein sequence ID" value="ADD40606"/>
        <property type="gene ID" value="Snas_0895"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0895"/>
    <dbReference type="eggNOG" id="COG1349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060699_3_0_11"/>
    <dbReference type="OMA" id="STHEPGF"/>
    <dbReference type="OrthoDB" id="1629121at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="27010" checksum="EFDC85E097B65F67" modified="2010-04-20" version="1">MLAQQRQAVIAERVRSHGAVRVAELVEEFGVSDMTIRRDLETLADRGLVSKVHGGATAVDIGSTDEPGFAAKSVRQKEAKEAIAAAAAKLVTPGQAIALSGGTTTWTLAHHLVGVAGLTVVTNSVPVADVFYRSGRGDQTVILTGGIRTPSDALVGPFAVASLKSINVDTLFLGVHGVNATAGFTTPNLMESETDKALIAAARKLVVVADSTKWEIVGIRTIACPDDADVLVTDAGLPEEARAALREAVGQLIIAGEDNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9H6</accession>
    <name>D3Q9H6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA polymerase-binding protein RbpA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rbpA</name>
        <name evidence="3" type="ordered locus">Snas_2984</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Bind 1 Zn(2+) per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a complex with the RNAP catalytic core and with free principal sigma factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase-binding protein RbpA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018229.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2984"/>
    <dbReference type="EnsemblBacteria" id="ADD42658">
        <property type="protein sequence ID" value="ADD42658"/>
        <property type="gene ID" value="Snas_2984"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2984"/>
    <dbReference type="eggNOG" id="ENOG5032TBE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134276_1_0_11"/>
    <dbReference type="OMA" id="CANGHET"/>
    <dbReference type="OrthoDB" id="1928204at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001000">
        <property type="term" value="F:bacterial-type RNA polymerase core enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01483">
        <property type="entry name" value="RbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038638">
        <property type="entry name" value="RbpA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025182">
        <property type="entry name" value="RNApol-bd_RbpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13397">
        <property type="entry name" value="RbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="114" mass="12552" checksum="F9C6437FFB29F21A" modified="2010-04-20" version="1">MVSGNAIRGTRVGGRPAGCPEHGEPVPRQFVDYWCVNGHHTRPSFSLRADIPETWECRRCGLPAGTDRESPPEPPTSRPFKTHLAYVMERRSPEDGEALLAEALASLRASRGET</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9I9</accession>
    <name>D3Q9I9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aldose 1-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2997</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018242.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2997"/>
    <dbReference type="EnsemblBacteria" id="ADD42671">
        <property type="protein sequence ID" value="ADD42671"/>
        <property type="gene ID" value="Snas_2997"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2997"/>
    <dbReference type="eggNOG" id="COG2017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052486_1_1_11"/>
    <dbReference type="OMA" id="SEHPYGI"/>
    <dbReference type="OrthoDB" id="710313at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09022">
        <property type="entry name" value="Aldose_epim_Ec_YihR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037480">
        <property type="entry name" value="YihR-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="302" mass="32739" checksum="4FCD7D122801F1AC" modified="2010-04-20" version="1">MSLTGEQFPIAAGGYRATVTEAGAGLRELTFQDQPLILSHGADQTAPAAFGQLLIPWPNRVDHGRYSFDGTAYQLDINEPAYDCAIHGLARWATWAPAEHEADRVRLTHRLLGSPGYPFRLDLDVEYTLDAARGLTVRLTATNSGTRPAPYAHGAHPYLTVGQPIDTCVVRVPADDHLPVDGRMIPYGPPQPVKGTDYDLRDGRLLGDQRIDLAFTGLTRGADGRAWVHLSGENRTTSFWLDRTQPWLEIYTADNVPSTLARQGLGVEPMTSPPNAFATGDDLVRLDPGGTITGCWGIAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Q1</accession>
    <name>D3Q9Q1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PSII_BNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4958</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020168.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4958"/>
    <dbReference type="EnsemblBacteria" id="ADD44597">
        <property type="protein sequence ID" value="ADD44597"/>
        <property type="gene ID" value="Snas_4958"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4958"/>
    <dbReference type="eggNOG" id="COG4447">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064269_0_0_11"/>
    <dbReference type="OMA" id="FFDRRHG"/>
    <dbReference type="OrthoDB" id="1293876at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028203">
        <property type="entry name" value="PSII_CF48-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14870">
        <property type="entry name" value="PSII_BNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048791" description="PSII_BNR domain-containing protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="PSII_BNR" evidence="2">
        <location>
            <begin position="37"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="357" mass="37743" checksum="A1281D59EB0F5AB1" modified="2010-04-20" version="1">MNRVLKRHVLPVCVATASLAAITLATPAHAHDGFKASNLSWQLTDTGVDNQFRGLAAVDDDTAWVAGTKGTVLRTTDGGDSWDNVSPAGAEGLEFRDIEAYDDEHAVALSIGEGEASRVYVTDDGGDSWHNSFTNAEPKAFYDCMAFFDAKHGVAMSDPVDGRIRFITTDDGGHSWDMLPPERSPEALAGEFAFAASGQCLVAADKRNGYLVTGGGETARVIHTPDRGQSWEAHDTPVASGPSAGIYAAAFRDTKRAILVGGDYTTPDAVKDAAAYTRKGVENFALSPGEPGQYRSSVAYVAGSIAITVGPTGSDLTVDNGRDWHRFDDGAFDSVECAKFACWASGPKGRIATLELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA01</accession>
    <name>D3QA01_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016284.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1003"/>
    <dbReference type="EnsemblBacteria" id="ADD40713">
        <property type="protein sequence ID" value="ADD40713"/>
        <property type="gene ID" value="Snas_1003"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1003"/>
    <dbReference type="HOGENOM" id="CLU_1833979_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="140" mass="15006" checksum="95BA1CA067E9B714" modified="2010-04-20" version="1">MNDNQDIRFDTTNVRGFAEYMHHLLTTKYEERARTISTKLAGGEGGGGDDRAYSTSGGSMGSSGVEYDGLQVGKTEVTNALVGEKVLKQFMRAWAGMANAAAYAAEEYSGQDGENATDLQGDFTPGEERVATQQGPLPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA07</accession>
    <name>D3QA07_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">4-diphosphocytidyl-2-C-methyl-D-erythritol kinase</fullName>
            <shortName evidence="8">CMK</shortName>
            <ecNumber evidence="2 8">2.7.1.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ispE</name>
        <name evidence="11" type="ordered locus">Snas_1009</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.148"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the GHMP kinase family. IspE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.148" evidence="2 8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1009"/>
    <dbReference type="EnsemblBacteria" id="ADD40719">
        <property type="protein sequence ID" value="ADD40719"/>
        <property type="gene ID" value="Snas_1009"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1009"/>
    <dbReference type="eggNOG" id="COG1947">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053057_1_1_11"/>
    <dbReference type="OMA" id="ACDALWG"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00061">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004424">
        <property type="entry name" value="IspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010376">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00154">
        <property type="entry name" value="ispE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5 8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="9">
        <location>
            <begin position="101"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="10">
        <location>
            <begin position="215"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="21"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD40719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="315" mass="32720" checksum="AE179CA06AAC2FC2" modified="2010-04-20" version="1">MTGALAFDDGSQAVRVRVPAKINLHLGVGDRRADGYHDLTTVYQGISLYDEVTVIAGQQPGVRVEVFGDDAEAVPLGTDNLAVKAVLALGEEFGVAPAVTVRIAKRIPIAGGLAGGSADAAAALVACSRLWGMPFTDRLVKVAAGLGSDVPFCLSGGTALGTGHGERVEEVTANGRYHWVVATADGQLSTPAVYAEVDRLRESGIGSYSSAVTELLEALRTGRAEELAPQLRNDMTEAAMSLRPQLREILTAGADDGALAALLSGSGPTTLFLARDVHHATALAGRLRMRRLAREVHCVHAPAFVSVGLSPAQPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA20</accession>
    <name>D3QA20_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1022"/>
    <dbReference type="EnsemblBacteria" id="ADD40732">
        <property type="protein sequence ID" value="ADD40732"/>
        <property type="gene ID" value="Snas_1022"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1022"/>
    <dbReference type="HOGENOM" id="CLU_972900_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="286" mass="30030" checksum="02648BA2E90E40A8" modified="2010-04-20" version="1">MSAPQQERPIPSPLATTPPPDLYPPTARQLPAAPAPSGPPMLRALSGQLSSPLPVILAGVGLLLLGLAFFLPLGEYTWGGKAGSDPMSEFSLYGGELTRRVSLSVGEQPAIAALPFTVAAAIALAASRRWLTFGRLASAGLGILVIASEFGRAYLWKTDLQDSIDRLGSFDDIDEGFGFSKKALEDVNVDFGVGLWLFIAGAALLVAAVMVIRPANRPGFVTPPHVAPQHPPAYPQVNQVPPQRFQAPPTAAAPAPAAAPTDADRAVEVHDDPPSLSIYKPPKKDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA77</accession>
    <name>D3QA77_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase domain protein TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016360.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1079"/>
    <dbReference type="EnsemblBacteria" id="ADD40789">
        <property type="protein sequence ID" value="ADD40789"/>
        <property type="gene ID" value="Snas_1079"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1079"/>
    <dbReference type="eggNOG" id="COG1082">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058777_0_0_11"/>
    <dbReference type="OMA" id="FQLADWT"/>
    <dbReference type="OrthoDB" id="1478083at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="17"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="266" mass="28660" checksum="CD35BC367EF7DC15" modified="2010-04-20" version="1">MNRFSLNHATTKHWDVFEAVEACARAEIGIGLWREPVADKGLEATAARVRDSGVTVTSLCRGGFLTTGTREALDDNRRAIDEAATLGTSELVMVCGGLPSGSRDLDAARETVAEAIAELAPHAAASGVRLAIEPLHPMFASDRCVISTLDQALDLAERFPATTVGVVVDTYHIWWDPTVWSAIERARGRISSFQVADWSTPLPAGVLTGRAQLGDGVIDLRRFRHAADAAGYDGLVEVEIFNDALWARPGAEVLAETLKRYAEHVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA86</accession>
    <name>D3QA86_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1088</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1088"/>
    <dbReference type="EnsemblBacteria" id="ADD40798">
        <property type="protein sequence ID" value="ADD40798"/>
        <property type="gene ID" value="Snas_1088"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1088"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="PGRANRH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="139"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="207" mass="21910" checksum="4E09E70C6C67070F" modified="2010-04-20" version="1">MRTVLVCVKTPESAQRITASAIRMGLAQAVRTVLTTDEVHMRMATTPADVVLVDVGLARPDPVQFTRTVLARAPRAGVVLVGAVDPRVAAMTVAAGARGVVRGGGEEGEDLVVALTQAIMLICPRAAGLNGGQRRVPTQRGGPVGLTEREMQVLRGMSEGKSNAEIGRDLFVSEDTIKTHARRLFRKLGARDRAHAVAEGFRGGIVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAB3</accession>
    <name>D3QAB3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018267.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3025"/>
    <dbReference type="EnsemblBacteria" id="ADD42696">
        <property type="protein sequence ID" value="ADD42696"/>
        <property type="gene ID" value="Snas_3025"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3025"/>
    <dbReference type="eggNOG" id="COG4993">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1331258_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="22212" checksum="EE6860653BF8D763" modified="2010-04-20" version="1">MTTPTPYSSEFSVPPQPVPGATVTEDMLPPVPPRPKALITGLILLALSGLSFEIGSLLEVIARFQASPSPYGSSPGNGVVMWLIYSVLVCGAIIVLGRLVWLGSPTGLLLLILGTGYATANLLLMNYTLVSDLVFEPSPPGLTDYVLQDPQTVGLRVAVVLALPALIAFCWRSSRRWSRRAGMIRHVRGFIRKGRPVTMLPPAMYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAC8</accession>
    <name>D3QAC8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3040</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018282.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3040"/>
    <dbReference type="EnsemblBacteria" id="ADD42711">
        <property type="protein sequence ID" value="ADD42711"/>
        <property type="gene ID" value="Snas_3040"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3040"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="TAMIREQ"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="4">
        <location>
            <begin position="154"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="147"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="224" mass="23887" checksum="40471F8A136B6452" modified="2010-04-20" version="1">MTTRVLVVDDQTVVRDGLVLILGLLPDIEVVGAAADGAEALRLVDEHHPDVVLMDLRMPRMDGAEATGRIKAAHPEVQIVVLTTYSDDESVFAALKAGARGYLTKDAGGEEIAAAIAAVRDGAAQLAPDVQRRLVDALASGDKTDTSEPAKPPRTDLPDGLTKRESEVLTLIAAGRSNAEIARQLYISEATVKTHINNLFTKAALRDRAQAVTYAYRHGLAPPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAE1</accession>
    <name>D3QAE1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmI</name>
        <name evidence="7" type="ordered locus">Snas_3053</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018295.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3053"/>
    <dbReference type="EnsemblBacteria" id="ADD42724">
        <property type="protein sequence ID" value="ADD42724"/>
        <property type="gene ID" value="Snas_3053"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3053"/>
    <dbReference type="eggNOG" id="COG0291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169643_4_2_11"/>
    <dbReference type="OMA" id="PKIKTHR"/>
    <dbReference type="OrthoDB" id="2046660at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_L35_non-mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_L35_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="SSF143034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00001">
        <property type="entry name" value="rpmI_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="64" mass="7555" checksum="F1CF8D046D8C9B40" modified="2010-04-20" version="1">MPKMKSHSGMRKRVKITGTGKLRRQRANRRHYLEHKSSRLTRRLDGRVDFAKADVKKVKRLLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAF5</accession>
    <name>D3QAF5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Arginine repressor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argR</name>
        <name evidence="13" type="ordered locus">Snas_3067</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Regulates arginine biosynthesis genes.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-arginine biosynthesis [regulation].</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the ArgR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018309.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3067"/>
    <dbReference type="EnsemblBacteria" id="ADD42738">
        <property type="protein sequence ID" value="ADD42738"/>
        <property type="gene ID" value="Snas_3067"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3067"/>
    <dbReference type="eggNOG" id="COG1438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097103_1_1_11"/>
    <dbReference type="OMA" id="IMGTICG"/>
    <dbReference type="OrthoDB" id="1640037at2"/>
    <dbReference type="UniPathway" id="UPA00068"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034618">
        <property type="term" value="F:arginine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00173">
        <property type="entry name" value="Arg_repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001669">
        <property type="entry name" value="Arg_repress"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020899">
        <property type="entry name" value="Arg_repress_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036251">
        <property type="entry name" value="Arg_repress_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020900">
        <property type="entry name" value="Arg_repress_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34471">
        <property type="entry name" value="PTHR34471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01316">
        <property type="entry name" value="Arg_repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02863">
        <property type="entry name" value="Arg_repressor_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01467">
        <property type="entry name" value="ARGREPRESSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55252">
        <property type="entry name" value="SSF55252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01529">
        <property type="entry name" value="argR_whole"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0678">Repressor</keyword>
    <keyword evidence="8 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Arg_repressor" evidence="11">
        <location>
            <begin position="5"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Arg_repressor_C" evidence="12">
        <location>
            <begin position="91"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD42738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="186" mass="19463" checksum="C2423B3DF71BF90A" modified="2010-04-20" version="1">MNAPVTKAARHARIAAIIDANPVQSQTALAGMLADEGISVTQATLSRDLEELGAVKVRGTDAAPATYAIFPEGDGPLRSATRPPERLLRRLRELLTGADHSGNLAVLRTPPGAAQFLASVIDRSGLADIVGTIAGDDTILVVARDGLSGAELAEQLLSWAGKDSETNNAKANRATTPRFDTEKENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAI9</accession>
    <name>D3QAI9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018343.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3101"/>
    <dbReference type="EnsemblBacteria" id="ADD42772">
        <property type="protein sequence ID" value="ADD42772"/>
        <property type="gene ID" value="Snas_3101"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3101"/>
    <dbReference type="HOGENOM" id="CLU_161148_0_0_11"/>
    <dbReference type="OrthoDB" id="2072147at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049694" evidence="1">
        <location>
            <begin position="27"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="127" mass="13438" checksum="EFC936B275D71630" modified="2010-04-20" version="1">MVNRTIALIAGTAAACGLAIAATATAASAHNSGVRTDVGTLTCGDAFADLDHRDYDYTFATDEVVVLHGPHETCEVIEVAKSGQRTDYHCYVMAGGDSYTYLRNVATGNQGWVNDEELTDGGSDYHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAN0</accession>
    <name>D3QAN0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formiminotransferase-cyclodeaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020247.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5039"/>
    <dbReference type="EnsemblBacteria" id="ADD44676">
        <property type="protein sequence ID" value="ADD44676"/>
        <property type="gene ID" value="Snas_5039"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5039"/>
    <dbReference type="eggNOG" id="COG3404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088419_0_1_11"/>
    <dbReference type="OMA" id="VAMVARY"/>
    <dbReference type="OrthoDB" id="1965647at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007044">
        <property type="entry name" value="Cyclodeamin/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036178">
        <property type="entry name" value="Formintransfe-cycloase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04961">
        <property type="entry name" value="FTCD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101262">
        <property type="entry name" value="SSF101262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FTCD_C" evidence="1">
        <location>
            <begin position="6"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="207" mass="21585" checksum="1329A03E14023783" modified="2010-04-20" version="1">MRDQKVGEWLEKLASKASAPGGGAAAALNAATGAALVSMVCNLTIGKPKYVEHELTMTDVLSKANELRNEALVLAEADAEAFSAVMAAYGLPKDSDEDKAQRTEAIQSALVRAAEVPLRIAGLAAEVIALSGRILDGANVNVLSDVAVAADSARSALRSAAINVEINLYSMKDEDLREELAGKLADHLGSLDTADRIVGSVNERITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAR6</accession>
    <name>D3QAR6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5076"/>
    <dbReference type="EnsemblBacteria" id="ADD44712">
        <property type="protein sequence ID" value="ADD44712"/>
        <property type="gene ID" value="Snas_5076"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5076"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_457723_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028208">
        <property type="entry name" value="Effector_pro_NleD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14891">
        <property type="entry name" value="Peptidase_M91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="688"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="736" mass="77953" checksum="BD47B1C4D195F01C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAT5</accession>
    <name>D3QAT5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44731">
        <property type="protein sequence ID" value="ADD44731"/>
        <property type="gene ID" value="Snas_5096"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5096"/>
    <dbReference type="eggNOG" id="ENOG5032YH1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_712959_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048378" evidence="2">
        <location>
            <begin position="31"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="393" mass="43365" checksum="C17C410FC4A56DAD" modified="2010-04-20" version="1">MTSTKRRWWFGVAVSVAAVSATVLTVATSAAEETGDVATTEGAFAVYMAPKGEGGTDGNDGLTPETPVRSLPRVHEILSEERPDADVEVRIKQGTYTSTPFHEWRFYVPGHSVSFMPIDYEPGDDAGDIAGLPTFRNATCDGSYCPGVWLQPRLPQDKDDPLYNGGDSNLRFYYLKVERYSNGGLSIFGNSERDWADENYDPPLHIQPTKGLNNNVVFGMQFRNIGNKWTNGRWGYGGIVLTNSSNNRIVNSHFVNIENTDHAGNIHGLYVTHHSSGNVIERNKFSYISGYPVKFRNQSNGNAVEENVIHRAGLISYYRGEFCDTACAVENNLPQQCASWSNRFYYNRLQGNYAGKQPSLWSLGPEGLENPGGKPCPAADGKKRVATGGNIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB71</accession>
    <name>D3QB71_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1178</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1178"/>
    <dbReference type="EnsemblBacteria" id="ADD40888">
        <property type="protein sequence ID" value="ADD40888"/>
        <property type="gene ID" value="Snas_1178"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1178"/>
    <dbReference type="eggNOG" id="ENOG502ZGRW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2107518_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="115" mass="12161" checksum="84A5F58EDA161E8D" modified="2010-04-20" version="1">MAYMSLSQTDAAARSARHPRDPEPVPSTKAAAAYALSVLALATAPFLGGVIPAIITLRLSAQADADIAASEGFLLGAARNRRARKNAFLAFGITGLAILTLFTWWVFRETVQSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBN0</accession>
    <name>D3QBN0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3242</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018483.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42912">
        <property type="protein sequence ID" value="ADD42912"/>
        <property type="gene ID" value="Snas_3242"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3242"/>
    <dbReference type="HOGENOM" id="CLU_1894910_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="134" mass="14533" checksum="2133EFE60FBB4D8B" modified="2010-04-20" version="1">MTDESTCGTGMAANAVLPTRMAEVVAAMADVLTRHTESLNPDDPAAEAEREAWLAIAAEQRQIARHLTASADRMEAQRELPWADHDMAALTSADATSAFTHFVTAQERLSDLLTEQLVEYRSMLADSRGTDAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBN6</accession>
    <name>D3QBN6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3248</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018489.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3248"/>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42918">
        <property type="protein sequence ID" value="ADD42918"/>
        <property type="gene ID" value="Snas_3248"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3248"/>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_5_1_11"/>
    <dbReference type="OMA" id="VRDYRWG"/>
    <dbReference type="OrthoDB" id="419160at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fn3_like" evidence="4">
        <location>
            <begin position="669"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="769" mass="80638" checksum="1475C61FEA8796C6" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBN7</accession>
    <name>D3QBN7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3249</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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    </organism>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
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        <subcellularLocation>
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            <topology evidence="4">Multi-pass membrane protein</topology>
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    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="MetI-like"/>
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        <property type="entry name" value="MetI-like_sf"/>
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        <property type="entry name" value="BPD_transp_1"/>
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            <end position="32"/>
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        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="237"/>
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    </feature>
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        <location>
            <begin position="71"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
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    </evidence>
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            <dbReference type="PROSITE" id="PS50928"/>
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    </evidence>
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            <dbReference type="EMBL" id="ADD42919.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
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    <sequence length="276" mass="29914" checksum="0CEF6D9D0C750A49" modified="2010-04-20" version="1">MSRVVRNRPNVAGALAGWIWLAVIIGPIYYILVTSLRPQADYFGESPLSWPSHPTLAAYGRVLDNGFAGFFLNSVTVTAATVALTLAVSIMAAYVITHGRGRFGREVFRLALLGIAIPIQAAIIPVYYLIVQLGLYDSLAALILPSVAFAIPITLLILTNFLRDVPRSLFESMRLDGAGEWTILLRLVLPMSRPALAAVGVYNALQVWNGFLFPLVLTQSADTRVLPLSLWSFKGEFAIDVPAVLAAVVLSVLPMLAAYVLTRRQLVSGMTAGFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
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            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
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                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
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            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
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        <property type="protein sequence ID" value="ADD40953"/>
        <property type="gene ID" value="Snas_1243"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1243"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="OMA" id="ITRSFPP"/>
    <dbReference type="OrthoDB" id="626204at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:transmembrane transporter activity"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
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    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
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        <property type="entry name" value="MFS_1"/>
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    </dbReference>
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        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <location>
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            <end position="39"/>
        </location>
    </feature>
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        <location>
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            <end position="68"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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            <end position="126"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="14"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="498"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="504"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="518" mass="53298" checksum="7FFB8306BF0A0D79" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUG0</accession>
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        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ordered locus">Snas_3305</name>
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    <organism evidence="1 2">
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
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                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
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            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="entry name" value="GDHRDH"/>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ADD42973.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="248" mass="25467" checksum="CF33F0192B01026B" modified="2010-04-20" version="1">MDSPGVALVTGASRGLGAAIARRLAADGWAVAVNYRSGAALADGVVDAIRADGGVAAAFGADVTDETAVTVLVDRITRELGPVGVLVTNATGPQPATAVADLTWQAHLDQLLFFVKSPTLLLRAVLPAMREAGRGRVIQIGSDIFERALPGMSAYVAAKGAQLGLTRSWARELGPSGITVNMVAPGWIPVERHADAPAADLEEYRDDVPLGRLGVPDDVAAAVSYLASDAAGFVTGQRITVNGGHTIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUK5</accession>
    <name>D3PUK5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3352</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018589.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43018">
        <property type="protein sequence ID" value="ADD43018"/>
        <property type="gene ID" value="Snas_3352"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3352"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_2_3_11"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048004" evidence="1">
        <location>
            <begin position="25"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="55"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="416" mass="45069" checksum="E6B3C9C0171700C8" modified="2010-04-20" version="1">MRKRLLIVAGLAAVMAAGSAVAIADPFDSERPNSGMDSDLLDSKLKALQEAGAPAVIAEVRDGDGVWEGAAGERVLGENTPPEPTDRVRASSVALSMIATVALQLADEGELDLDAPIDEYLPDVLPYEDTITTRQMLNHTSGVPDYFVHIYGSLHQGDPTDVRDNRLNEYTPEELIAMATEKPLDFEPGSKFAYSNTGYTVIGLLIEDLTGKSIEDAIGERVLDPAGLDDTYMMARDGELVVEGPHPNGYFDAGDGKEMIDVSELHPSQFWAGVAAVSNPRDINRFYKAMSDGTLLSPERLAEARELSPQSEKTYGLGLQAFVKLPDNCAPIPDRIAYGHGGDGMGYLTWTAHSPDANRQVTFTFTLGYELNPTEELNKAWRGLLYAGLCDVDINDPAVSKTLPDQSPMTLESAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUL8</accession>
    <name>D3PUL8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018602.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3367"/>
    <dbReference type="EnsemblBacteria" id="ADD43031">
        <property type="protein sequence ID" value="ADD43031"/>
        <property type="gene ID" value="Snas_3367"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3367"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_2_0_11"/>
    <dbReference type="OMA" id="WGIWVLI"/>
    <dbReference type="OrthoDB" id="2057904at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="2">
        <location>
            <begin position="24"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="133" mass="14813" checksum="50996ECBDC3947E7" modified="2010-04-20" version="1">MSAGAPLRSCEPCGPPSGTDHAQCPLRQALEHVTSRWGTWILIELRDGPLRFHELRDRIPGVSEKMLSQTLRPLQRDGFVWREVEPTIPPKVTYGLTTRGEGAGKPLAELFDHLMDNATDIVDDRAAWDARSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUR5</accession>
    <name>D3PUR5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase with PASTA sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5305</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020510.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5305"/>
    <dbReference type="EnsemblBacteria" id="ADD44939">
        <property type="protein sequence ID" value="ADD44939"/>
        <property type="gene ID" value="Snas_5305"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5305"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0810">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_469211_0_0_11"/>
    <dbReference type="OrthoDB" id="912616at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03793">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00740">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51178">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="3">
        <location>
            <begin position="492"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="581" mass="60151" checksum="948F86958485550B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV45</accession>
    <name>D3PV45_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016669.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1391"/>
    <dbReference type="EnsemblBacteria" id="ADD41098">
        <property type="protein sequence ID" value="ADD41098"/>
        <property type="gene ID" value="Snas_1391"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1391"/>
    <dbReference type="HOGENOM" id="CLU_121293_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="167" mass="18892" checksum="F52AA90FBD9DEA15" modified="2010-04-20" version="1">MGIVADRLASTRIELSTPDGLVTGVLRSLDDVSFEFRDGSVRHYNERGLERQLSNLLARLWTDYRQARFAAVAEATGRPAEPFKPWRANGRRYEAEREETVAEGMSTGHRVFVSTTGLRRWNVVIRDGSLSSVDETAFAAEVGSGYAAMVLDWRRKLRLLRAKHFPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVK6</accession>
    <name>D3PVK6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018691.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3456"/>
    <dbReference type="EnsemblBacteria" id="ADD43120">
        <property type="protein sequence ID" value="ADD43120"/>
        <property type="gene ID" value="Snas_3456"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3456"/>
    <dbReference type="eggNOG" id="ENOG50337IW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1767024_0_0_11"/>
    <dbReference type="OMA" id="EHAVSRM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="47"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="148" mass="15962" checksum="0BC2B8E645E50BEB" modified="2010-04-20" version="1">MALRDFLERFRPAGAPGAAAVRGVPADRVAERAAELEPLLAVLSATEQEAERIRADARAEAARLRAEATRRAEELLHRARTEAAALRAESIAQARATADDDSQVEAAVRDAVSMVDALARARMPDLVHQAEDWARRVLDADRTVTGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVS2</accession>
    <name>D3PVS2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5411"/>
    <dbReference type="EnsemblBacteria" id="ADD45043">
        <property type="protein sequence ID" value="ADD45043"/>
        <property type="gene ID" value="Snas_5411"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5411"/>
    <dbReference type="HOGENOM" id="CLU_1453588_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="186" mass="21666" checksum="0A71EEFD42F0033E" modified="2010-04-20" version="1">MFFSHRSTRHHRLPAMYDELTLPSDYVLYQRVSLLSDIAVMVECGHPIDCAFDGRHFYYHCTGTEPTGADRIEWYCGRHRLGYADDIDRAVWTQTFRLLPKARRARTAYQRRSLLLATHALVKVSLSDPRCPVVEWIGHKRLGDRSFHTDHDRALAHRLKDRRVEAAASRHPLRRAANSLVNPFEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVT0</accession>
    <name>D3PVT0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020622.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5419"/>
    <dbReference type="EnsemblBacteria" id="ADD45051">
        <property type="protein sequence ID" value="ADD45051"/>
        <property type="gene ID" value="Snas_5419"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5419"/>
    <dbReference type="HOGENOM" id="CLU_1969194_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="129" mass="13737" checksum="DD72231311568DE9" modified="2010-04-20" version="1">MSEPTTATEPSAPTPKSDGGQAGDLCRRILAVHDRVSTASTDLNRLFAQTAIELSGLLADGYQLHHKTLTAGFDDAAFQLHHMLVALSNVQIDVSTVTDTAAKLPTLTKAFAHERHIDLNATPPDEPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVT1</accession>
    <name>D3PVT1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020623.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5420"/>
    <dbReference type="EnsemblBacteria" id="ADD45052">
        <property type="protein sequence ID" value="ADD45052"/>
        <property type="gene ID" value="Snas_5420"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5420"/>
    <dbReference type="eggNOG" id="ENOG5031VKH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_993620_0_0_11"/>
    <dbReference type="OMA" id="RMENIAC"/>
    <dbReference type="OrthoDB" id="2002450at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032724">
        <property type="entry name" value="DddA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14428">
        <property type="entry name" value="SCP1201-deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="280" mass="30283" checksum="B660DBD2EED39242" modified="2010-04-20" version="1">MTTFEQLVAAVNNAVAEVGEARTLAAQGIQHVARSSTRMENIACGSSSYRLRDVLAALTAAITAIEHSNTAAASASAQLNTYLAAIGNSTTTVEAQPEAAPPPAAAESLDSTPRLPDGGIDFHALAKRLGLLEARPTEQPPFDPRRFNPACWQGLKPYDQAGTAEGNLFIAPGKRWNTRPMQASKLEVGPQSDLHPQWRSRKAPWHIEGKIAAYMRQKGFTDGCVYLNARPCSGPDGCARNLPDLLPVGSTLHVHARYIDRTGETRFYYREYRGTGKALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVT5</accession>
    <name>D3PVT5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5424"/>
    <dbReference type="EnsemblBacteria" id="ADD45056">
        <property type="protein sequence ID" value="ADD45056"/>
        <property type="gene ID" value="Snas_5424"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5424"/>
    <dbReference type="HOGENOM" id="CLU_1401713_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="194" mass="21078" checksum="78CEE4F6432767D7" modified="2010-04-20" version="1">MTYDDAHHPAAAEALEEYCQHAIETMTTHGGMMPAPTVYMFSGDGEHLDSLQGYVIARPSHSGGDAGDAIRQLGLLPGVLRCDRIVIAWEHRTTATLLGRGGDHQTGIAAVEAARDHRVVTWRPFTVHHGDYGIHGTRSMIATWGRAQELRTRLPVPIADAVRVWTNASCASITSTVAKLEAAGYLVSLFHEGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVX4</accession>
    <name>D3PVX4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helix-turn-helix type 11 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5463</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020666.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5463"/>
    <dbReference type="EnsemblBacteria" id="ADD45095">
        <property type="protein sequence ID" value="ADD45095"/>
        <property type="gene ID" value="Snas_5463"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5463"/>
    <dbReference type="eggNOG" id="COG2378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041141_1_0_11"/>
    <dbReference type="OMA" id="PLHMEYW"/>
    <dbReference type="OrthoDB" id="1654295at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028349">
        <property type="entry name" value="PafC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016838">
        <property type="entry name" value="PafC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="4"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="313" mass="35360" checksum="FACBB87EFA7E4C7D" modified="2010-04-20" version="1">MLPTSARLLKLLSLLQTHREWSGTDLAERLEIDVRTVRRDVSKLRTLGYPVNAAPGVAGGYQLGAGAKMPPLLLDDEEAVAVAMGLRTAASGSISGIEESSVRALTKLEQVLPPRLRTRVNAMQTVTVSTASSNDPVDAEALTIIATAARDRERMRFEYRTHDGSESIRNVEPHRLVHTGRRWYLQAFDIDREDWRSFRVDRMRPRTPTGPSFEAREIPEFGVDRFAIWKGQRYQARYTLHAPVAQMAEQIPERYGMLEAIDDETCTLYTGSNWLDGLAMWLVNLGVDFEIHEPPELVEYLRQMNTRLARALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVY7</accession>
    <name>D3PVY7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminopeptidase N</fullName>
            <ecNumber evidence="4">3.4.11.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Alanine aminopeptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Lysyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Snas_5477</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5477"/>
    <dbReference type="MEROPS" id="M01.012"/>
    <dbReference type="EnsemblBacteria" id="ADD45108">
        <property type="protein sequence ID" value="ADD45108"/>
        <property type="gene ID" value="Snas_5477"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5477"/>
    <dbReference type="eggNOG" id="COG0308">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007335_1_1_11"/>
    <dbReference type="OMA" id="EGMHRFT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012778">
        <property type="entry name" value="Pept_M1_aminopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02412">
        <property type="entry name" value="pepN_strep_liv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M1" evidence="13">
        <location>
            <begin position="223"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1_C" evidence="14">
        <location>
            <begin position="517"/>
            <end position="815"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD45108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="838" mass="93271" checksum="0C75B3F87C060467" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW40</accession>
    <name>D3PW40_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020732.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5530"/>
    <dbReference type="EnsemblBacteria" id="ADD45161">
        <property type="protein sequence ID" value="ADD45161"/>
        <property type="gene ID" value="Snas_5530"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5530"/>
    <dbReference type="eggNOG" id="COG1937">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1348120_0_0_11"/>
    <dbReference type="OMA" id="SKRAWIR"/>
    <dbReference type="OrthoDB" id="1893059at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="209" mass="23258" checksum="45587F712D9C5EEF" modified="2010-04-20" version="1">MSDPIAERVETRYERAERVLAMPVLIAAIASVPGVLLSLWGPGTWATAGSVINLCSGALMWMEFAVLFVLSENKFRWLRRNWWLCLIIVVTLPAVVYSLGPAQLLRIVYSVSTLRILRVRKIIKAGNIVQDKLKLRGWARTLVLAVVILVSMVLIGVLILDPNSDTWVVAELLADSVGLGPALILVGAVTLTGLVLWRKRRRRTARVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW42</accession>
    <name>D3PW42_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LicD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1495"/>
    <dbReference type="EnsemblBacteria" id="ADD41199">
        <property type="protein sequence ID" value="ADD41199"/>
        <property type="gene ID" value="Snas_1495"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1495"/>
    <dbReference type="eggNOG" id="COG4783">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_602555_0_0_11"/>
    <dbReference type="OrthoDB" id="1578335at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="454" mass="51162" checksum="64A8518E2D78D95B" modified="2010-04-20" version="1">MQVRPRAIAARTIARYPVHRVLPPSALKTYAVLKYHGDHSTQDDIAAVMRKLGAIPVRYHSTAIVAARAAFRTGLDEQAESLLERLERRFPESADAAKLRAEFHAYHNRYGEALTAARHARLLDPPAAGSAAQTVKYGYHALDHDAADRNAVEMVRRFPVANSVLWAAAKACISGAQFDQLYRAWREGIAGRDEREALLLSVRQLATAAARGHRVEEGIALFRRAITQLHEGDAAPVHNSTKLAGRGAWNAIADIRQLLDDAGVPFFFAAGTALGFERVGRPLSDDGDIDVGIRAEDFDPERLTALVAAHPRFVVDPHPLSKKVHMRHRGGCPVDFFRYYDEGEYVWHDGVFVRWWNTPFKIERREFQGLSIPLPSNPDLYLTENYADWRTPNPEFDSFTEEAPNCTVHWPEYHRLHFMRRAFKAMIAHDRRSAAGDLRRAEQSDLADLIGRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWG6</accession>
    <name>D3PWG6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3525</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018759.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3525"/>
    <dbReference type="EnsemblBacteria" id="ADD43188">
        <property type="protein sequence ID" value="ADD43188"/>
        <property type="gene ID" value="Snas_3525"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3525"/>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_0_2_11"/>
    <dbReference type="OMA" id="DETWYLG"/>
    <dbReference type="OrthoDB" id="1942521at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048036" evidence="1">
        <location>
            <begin position="30"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="52"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="33547" checksum="97A06128897D7421" modified="2010-04-20" version="1">MRTRTVLTVVAAALALSACGTSDPGSESADGGKTRTIEHAMGSTEIPVKPKKVVVLDTDKIDTVMSLGVKPIAAARPDEAELPKYLGDLSDVKVVGTLTAPDTEAIDKLNPDLILGTKFRQEEFYDELSEIAPTVFTEAVGTTWKENFLLDGDAIGKRDKAKDLLDEYETRAKDFGEKLGDASKTTVSIIRFMPDHIRMYGPDSFSGIVVGDTGLARPELQQLKDAKDKRFAELSSEKLDEADADVLFYCAYGEAAAKAQAESTGGSLWKKMSVVKDGNDHEVDDEIWMTGIGVTAANLILDDLEKHVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWL8</accession>
    <name>D3PWL8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CRISPR-associated protein, Csd2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018811.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3579"/>
    <dbReference type="EnsemblBacteria" id="ADD43240">
        <property type="protein sequence ID" value="ADD43240"/>
        <property type="gene ID" value="Snas_3579"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3579"/>
    <dbReference type="eggNOG" id="COG3649">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071770_2_0_11"/>
    <dbReference type="OMA" id="KWGRSLH"/>
    <dbReference type="OrthoDB" id="598606at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006482">
        <property type="entry name" value="Cas7_Csh2/Csh2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013418">
        <property type="entry name" value="CRISPR-assoc_prot_Csd2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05107">
        <property type="entry name" value="Cas_Cas7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02589">
        <property type="entry name" value="cas_Csd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01595">
        <property type="entry name" value="cas_CT1132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="293" mass="32319" checksum="BEBF3BF5D134FFD2" modified="2010-04-20" version="1">MSEAHLDPTMRHDAVLLFDVTDGNPNGDPDAANQPRMDDETGQGIVTDVAIKRKIRDTVSLLKGDDPRFGIFVEAGHALNTRIAQALKESADDSDNARQWICDHYFDVRMFGAVLSTGDKIPGSKKRGAGQVYGPTQLTFARSIDAISPVEHTITRVTQTKQADIDAGESTELGAKWTVPYGLYRTHLHYSAPKATKTGVTADDLHTLWKAIQFMFEHNHSAARGEMKLCGLYVFSHSSAVGDAPAHQLFNTIAISPLEADKPPRHHTDYRRQFEKASVPSRITSTVLTDLWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWL9</accession>
    <name>D3PWL9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018812.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3580"/>
    <dbReference type="EnsemblBacteria" id="ADD43241">
        <property type="protein sequence ID" value="ADD43241"/>
        <property type="gene ID" value="Snas_3580"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3580"/>
    <dbReference type="eggNOG" id="ENOG502Z7WH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_468353_0_0_11"/>
    <dbReference type="OMA" id="TIRDRFY"/>
    <dbReference type="OrthoDB" id="924061at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010144">
        <property type="entry name" value="CRISPR-assoc_prot_Csd1-typ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09709">
        <property type="entry name" value="Cas_Csd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="618" mass="68487" checksum="470D3F48543AA080" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWS5</accession>
    <name>D3PWS5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3639</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018868.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3639"/>
    <dbReference type="EnsemblBacteria" id="ADD43297">
        <property type="protein sequence ID" value="ADD43297"/>
        <property type="gene ID" value="Snas_3639"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3639"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="VEIAMWA"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="148"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="215" mass="23162" checksum="CBCAAA49521456D0" modified="2010-04-20" version="1">MSIRVLIADDQPIVRTGLTMLLDAQPDIEVVGAAADGREAVRLALQLRPDVGLFDIRMPLMDGIEATRRLAGPDVTDPLPIVVITTFDLDEYVHEALKAGARGFLLKDAGPALLTQAIHAAADGNALIAPSVTVRLIAAFAQTHTSPPPQPIERLTAREEEVLVSVAQGRTNNEIASELYITQSTVKAHLASLMRKLGARNRVEVAMWAHETGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWW0</accession>
    <name>D3PWW0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5553</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020755.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5553"/>
    <dbReference type="EnsemblBacteria" id="ADD45184">
        <property type="protein sequence ID" value="ADD45184"/>
        <property type="gene ID" value="Snas_5553"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5553"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="FARAIMS"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="219"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="258" mass="26795" checksum="5DB809C7BF5F9C69" modified="2010-04-20" version="1">MNETVLSGTGLAKSFGSTLALAGVDFGVQRAEAVAIMGPSGSGKSTLLHCLAGIMRPDAGEVRLLDQRIDTMSEAQRSRLRRTRFGFLFQFGQLLPELTAVENVALPLMLGGTGKSTALREAHQWFPNLGLTGLDKRRPGELSGGQAQRVALARALVSGPAVVFADEPTGALDQATGTETMRTLVASTKGQRASLIVVTHDASVAAHCDRTIEIRDGLVTSDTSRPAPVEALAPSGSGQPASTTSPIPGSVPGRAGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX27</accession>
    <name>D3PX27_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5621</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020822.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5621"/>
    <dbReference type="EnsemblBacteria" id="ADD45251">
        <property type="protein sequence ID" value="ADD45251"/>
        <property type="gene ID" value="Snas_5621"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5621"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_44_3_11"/>
    <dbReference type="OMA" id="IERGWAR"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="195" mass="20819" checksum="45F6381A6498C776" modified="2010-04-20" version="1">MGNREQLLDAAKQCLIQKGYERTTVRDISDLAGVSKAAIGYHFGSKEALLNAALFEVLGGGDSGLSPTAEAADPDATPVQRFTALWTNMMAAYGGEDKTFWAANLESVLVAYRDASVREHLSAGFEEGRSGITSVLTGVEESQVPPETIRTLGSVQMALLSGVMIQYLVNPDTAPSAEELFRGIHALARITPDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX40</accession>
    <name>D3PX40_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exonuclease RNase T and DNA polymerase III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020835.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5634"/>
    <dbReference type="EnsemblBacteria" id="ADD45264">
        <property type="protein sequence ID" value="ADD45264"/>
        <property type="gene ID" value="Snas_5634"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5634"/>
    <dbReference type="eggNOG" id="COG0847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047806_5_0_11"/>
    <dbReference type="OMA" id="RQIEWYA"/>
    <dbReference type="OrthoDB" id="1985371at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="1">
        <location>
            <begin position="10"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="226" mass="24717" checksum="A3773B678871DE89" modified="2010-04-20" version="1">MDDSTWHTGPLLGFDTETTGIDTTTARIVTAAIVNGDDVASWLINPGIDIPAAASNVHGISTEHARANGTEPALALSEIGRALTKAAEEDTPVVVYRAGYDLTLLSHELDRYSLPQVPWERLKVLDPFVLDKKADKFRRGKRTLSAVCTHYDVDLSGAHSADADARAAVSLARAIGQRHKALAAMNITELHTAQIAWHADDAASLEAYFRRQGKQETIDRRWPLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXA5</accession>
    <name>D3PXA5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016939.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1666"/>
    <dbReference type="EnsemblBacteria" id="ADD41368">
        <property type="protein sequence ID" value="ADD41368"/>
        <property type="gene ID" value="Snas_1666"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1666"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063440_10_0_11"/>
    <dbReference type="OMA" id="LAADWED"/>
    <dbReference type="OrthoDB" id="1706427at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="37"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="109" mass="12102" checksum="7C585D8EA7EE6CF9" modified="2010-04-20" version="1">MVAKIKVTNTVAQVLSCFLSDIGAERYGRDMIKETGLPSGTLYPILARLERAEWLSASWEDIDPETEGRPARRFYRLTPDGVVAARDELAALRDQLTRALGPIGKPRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXC0</accession>
    <name>D3PXC0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MMPL domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1683</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016954.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1683"/>
    <dbReference type="EnsemblBacteria" id="ADD41383">
        <property type="protein sequence ID" value="ADD41383"/>
        <property type="gene ID" value="Snas_1683"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1683"/>
    <dbReference type="eggNOG" id="COG2409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005108_5_2_11"/>
    <dbReference type="OMA" id="WPAVLKP"/>
    <dbReference type="OrthoDB" id="149255at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="529"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="555"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="596"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="638"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="674"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="MMPL" evidence="7">
        <location>
            <begin position="57"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="MMPL" evidence="7">
        <location>
            <begin position="398"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="737" mass="78486" checksum="26D505AC39BB95CB" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXG5</accession>
    <name>D3PXG5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1730"/>
    <dbReference type="EnsemblBacteria" id="ADD41428">
        <property type="protein sequence ID" value="ADD41428"/>
        <property type="gene ID" value="Snas_1730"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1730"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_5_1_11"/>
    <dbReference type="OMA" id="THPKRLE"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="113" mass="11994" checksum="0FAEC6C32FC27296" modified="2010-04-20" version="1">MSAEIEAGVPPAAALFHSLSDETRLRIVQYLATGEARVVDLTERLGLAQSTVSKHLACLRDCGLVNSRAEGRQSFYSLTRPELMDLLIAAEGVLTATGHAVAVCPTDATVETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXT7</accession>
    <name>D3PXT7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integral membrane protein TerC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3760</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TerC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018988.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43417">
        <property type="protein sequence ID" value="ADD43417"/>
        <property type="gene ID" value="Snas_3760"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3760"/>
    <dbReference type="eggNOG" id="COG0861">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045644_0_1_11"/>
    <dbReference type="OMA" id="ADHAREY"/>
    <dbReference type="OrthoDB" id="1917125at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022369">
        <property type="entry name" value="Integral_membrane_TerC_rswitch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238:SF0">
        <property type="entry name" value="PTHR30238:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03718">
        <property type="entry name" value="R_switched_Alx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="321"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="399" mass="43085" checksum="B807968604DF1B4E" modified="2010-04-20" version="1">MTVPFWVWALTIVGVLVILTVDLAIIGRRPHEPSTKEATLWVAFYLGLAAAFGAGVWLFSEPRYGGEFFAGWITEYSMSVDNLFVFILIMSSFAVPRKYQQKVLMIGIIMALILRAVFIGIGAGLVNQFVWVFFIFGAFLIFTAIQLLRGDDNDDENYENAVIRWTRRVVPVSKDYDGAKITTKVNGRRVATPMLIVMVAIGSADLLFAVDSIPATFGLTKEAFLVFTVNVFALMGLRQLYFLLGGLLQRLVYLNYGLAAILGFIGVKLVFHALHDNDVPFINGGKPVPGIPDINTWVSLGVIVGILVVATVASLIASRGKELPAPGKPEAGSETEGGSETAQGQVEPGSGEAHPKEGTSHPGGGKAHPATVHHLRLSKPLNVKAPGERPGPFVVGVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXX4</accession>
    <name>D3PXX4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">UDP-N-acetylglucosamine--lysosomal-enzyme N-acetylglucosamine phosphotransferase</fullName>
            <ecNumber evidence="8">2.7.8.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5673</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the stealth family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.17" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020874.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5673"/>
    <dbReference type="EnsemblBacteria" id="ADD45303">
        <property type="protein sequence ID" value="ADD45303"/>
        <property type="gene ID" value="Snas_5673"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5673"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033996_0_0_11"/>
    <dbReference type="OMA" id="DAACKNN"/>
    <dbReference type="OrthoDB" id="623081at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003976">
        <property type="term" value="F:UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031358">
        <property type="entry name" value="Stealth_CR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021520">
        <property type="entry name" value="Stealth_CR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031357">
        <property type="entry name" value="Stealth_CR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031356">
        <property type="entry name" value="Stealth_CR4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17101">
        <property type="entry name" value="Stealth_CR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11380">
        <property type="entry name" value="Stealth_CR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17102">
        <property type="entry name" value="Stealth_CR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17103">
        <property type="entry name" value="Stealth_CR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0270">Exopolysaccharide synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Stealth_CR1" evidence="5">
        <location>
            <begin position="235"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Stealth_CR2" evidence="4">
        <location>
            <begin position="272"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Stealth_CR3" evidence="6">
        <location>
            <begin position="423"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Stealth_CR4" evidence="7">
        <location>
            <begin position="497"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="549" mass="62229" checksum="84E90DCC37143850" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY40</accession>
    <name>D3PY40_STANL</name>
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        <submittedName>
            <fullName evidence="3">YhgE/Pip N-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020940.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5739"/>
    <dbReference type="EnsemblBacteria" id="ADD45369">
        <property type="protein sequence ID" value="ADD45369"/>
        <property type="gene ID" value="Snas_5739"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5739"/>
    <dbReference type="eggNOG" id="COG1511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004534_1_1_11"/>
    <dbReference type="OMA" id="WHPRSWV"/>
    <dbReference type="OrthoDB" id="1240965at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017500">
        <property type="entry name" value="Phage_infect_YhgE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023908">
        <property type="entry name" value="xxxLxxG_rpt"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03061">
        <property type="entry name" value="pip_yhgE_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03057">
        <property type="entry name" value="xxxLxxG_by_4"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="488"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="530"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="560"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="596"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="637"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="683" mass="70090" checksum="35CDAC2DD7668C4D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYK0</accession>
    <name>D3PYK0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
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        <property type="protein sequence ID" value="ADD43433"/>
        <property type="gene ID" value="Snas_3776"/>
    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_1601693_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="166" mass="16863" checksum="4CD99BE0D96ABC24" modified="2010-04-20" version="1">MSFNSPPPSFLPPSPPRKSRAGGIILLLAGILAAVSPFISWVPALGQGKSSLKYFADQFGQVEGVSALSNPQYWFYAILGGAGLAIIFGLIGLAGSKGVNITVGIFGLLAAIAISFPPIWMLTGADSAQSLAKGLGQLGAGYYGAAVAGFLALVGMLFAFIGAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYL3</accession>
    <name>D3PYL3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3789"/>
    <dbReference type="EnsemblBacteria" id="ADD43446">
        <property type="protein sequence ID" value="ADD43446"/>
        <property type="gene ID" value="Snas_3789"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3789"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143479_0_0_11"/>
    <dbReference type="OMA" id="GHINAVP"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="31"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="147" mass="15612" checksum="CA16AB254A723D95" modified="2010-04-20" version="1">MPVTTNSQPPVTSASIIVLTLARRIESELNAGLAPLDLTVSRLGLIGHINAVPGASFSDLARMSSTSVQTVHATVKTLVRSGLVRDRKARAGSASTIELTEQGTRLLAAAKDVIAEVDERLFGAEADPVQREIGRAVLDAFRDQRPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ26</accession>
    <name>D3PZ26_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021026.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5825"/>
    <dbReference type="EnsemblBacteria" id="ADD45455">
        <property type="protein sequence ID" value="ADD45455"/>
        <property type="gene ID" value="Snas_5825"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5825"/>
    <dbReference type="HOGENOM" id="CLU_745792_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="371" mass="39688" checksum="32C762EAB2C04C36" modified="2010-04-20" version="1">MVEVAEIIKKAEGVVERANDLRALELLGIGPGNPGAIPGFTSDWVNEMGDSGAQAWSRWDQNNDLSASGIDASRYGNEFDWIVPHFKTMSLDEGGANIYVDYEVVLGQLKEASLALGPDDEQYVESPMVKSIADLQEGWTGSFPVAFREKFANKLQYITPAQKRVIQELGAALKGHWNIVQGARESLFSIADATEKKLIKTIQDDYAGSYEGSQDGPNGAIGLAIFGCAIAILAIPAAGPAGSVGFTLAILNAVKGAGDVWLASQSTIEVPDAVEKEPVEITGGTVEEIIGSMNDRITELAQKVTSEESGHADAIQASITSIEECMARGDQTASYKDNPAEDPSGKLVPHRLAWADEQPELGSDQFDHTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ78</accession>
    <name>D3PZ78_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NLP/P60 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5879</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021078.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5879"/>
    <dbReference type="MEROPS" id="C40.007"/>
    <dbReference type="EnsemblBacteria" id="ADD45507">
        <property type="protein sequence ID" value="ADD45507"/>
        <property type="gene ID" value="Snas_5879"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5879"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1579">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034085_1_0_11"/>
    <dbReference type="OMA" id="VMVHAST"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048717" evidence="3">
        <location>
            <begin position="41"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="4">
        <location>
            <begin position="218"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="44"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="148"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="333" mass="35664" checksum="9B38F80F800CD9DD" modified="2010-04-20" version="1">MAIRARTTSSSSRSTVVRLTVALAAAALAATLAAPQPAFAEPSIKQLEKKVDKASAELEIIVEDYNELNQELKDLEKQHAETGKELKPLRSRAEQTATEVGDIAASLYRAGPAVTVTPIISGSPDTLIERLSLLEFMSLEQDDLVDELAATTKILESEELEIDDLERERGKLKAKKSKKQRAITRDRDRLRDLRDIAMGQGYRDNPGLKAPPIPGGDAGAAATAVRFVHGALGSPYQWGGVGPHGYDCSGLTSAAWGSAGVSLPHNAAAQYRSIPHVGRGELQPGDLVFYYGDIHHVGMYVGQGKIIHAPSEGQNVRVSGIDELPVSGYGRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZD8</accession>
    <name>D3PZD8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetylornithine transaminase</fullName>
            <ecNumber evidence="3">2.6.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1916</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.11" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017183.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1916"/>
    <dbReference type="EnsemblBacteria" id="ADD41612">
        <property type="protein sequence ID" value="ADD41612"/>
        <property type="gene ID" value="Snas_1916"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1916"/>
    <dbReference type="eggNOG" id="COG0160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_10_0_11"/>
    <dbReference type="OMA" id="MVPNYNP"/>
    <dbReference type="OrthoDB" id="1322538at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003992">
        <property type="term" value="F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="417" mass="44169" checksum="13AB2739C1B45F1B" modified="2010-04-20" version="1">MAQLSPLLKQATPVVVDHGEGVYLFDSDGRRYLDFTAGIGVTSTGHCHPKVVQAAQEQVGKLIHGQYTTVMHQPMLELTRRLGEVLPPGLDSLFYSNSGSEAVEAALRLSRQATGRPNVVVFHGGFHGRTVAASTMTTSGTRFSAGFSPLMSGVHVAPFPNAYRYGWDERTATEFALRELDYLFATLSAPNETAAFFIEPVLGEGGYVPANTAFLQGLRERADEHGILLVIDEIQTGFGRTGKFWGHDHFDVRPDIVLIAKGLASGFPISGIAASKELMSKAWPGSQGGTYGGNAVACAAALATLEVIQEEGLVDNAAARGLQLLEGARQIGDKTPAIGDVRGLGLLVGSEFTTPDGKPDTATAQAAQKEAAARGLLMLTCGAHMNVVRMIPALVVNSEQIDEALGIWADVVADVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZH3</accession>
    <name>D3PZH3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017218.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41647">
        <property type="protein sequence ID" value="ADD41647"/>
        <property type="gene ID" value="Snas_1951"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1951"/>
    <dbReference type="eggNOG" id="ENOG5033AVY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134220_0_0_11"/>
    <dbReference type="OMA" id="ANPGMTI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025363">
        <property type="entry name" value="DUF4267"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14087">
        <property type="entry name" value="DUF4267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="139" mass="14500" checksum="62DA68F5618E109B" modified="2010-04-20" version="1">MIQALNDSNSERKWSRTIRVVNAVLAAGTAAFAVAALIHPPLAVAGTVTDSTTFYVQIYAARAIPLGLAVAVLALSRNRRALPALLLVAGVVQLADVVIGVSQANPGMTITAVIAAAVPLWSAWYLRAERGSRRALGVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZL3</accession>
    <name>D3PZL3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Terpene synthase</fullName>
            <ecNumber evidence="2">4.2.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the terpene synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.-" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017258.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1991"/>
    <dbReference type="EnsemblBacteria" id="ADD41687">
        <property type="protein sequence ID" value="ADD41687"/>
        <property type="gene ID" value="Snas_1991"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1991"/>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047127_0_0_11"/>
    <dbReference type="OMA" id="VDGNHHW"/>
    <dbReference type="OrthoDB" id="1869158at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034686">
        <property type="entry name" value="Terpene_cyclase-like_2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01020">
        <property type="entry name" value="Terpene_Cyclase_Like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="373" mass="41475" checksum="55AF6C90BDA62508" modified="2010-04-20" version="1">MTTQARVLPTGPVGLGTDLARLFSVPPPKAAGSAGKASPTPKGSVTVPELYCPDAVRDDAALGAEVDRRLAVWGREEIGLPDEHVDKLGKCGYGRLIMLTHPDCDDPDRLLAAAKCAVAEWSVDDLYLDGDSAEPEPERLGPRLALAYAAMAPARVPPPPYREPVKERIREDLCLRMIHSAWKNLARYASHTQVFRLRHELAVMFVAYNQEAEWHITERVPPTWEFLLHRWENAFCPCMVLTDVVGGYEVPVFEYADPRVRRVFTTAGVASVLVNDLYSLEKEKEINGFDYSLPGVLVAQDGCTLQEAVDRTAELHDELVRFVESESALLSANHTPMLARFLTGVWNWMGGGKEWHATSRRYHKQESDNSDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZN1</accession>
    <name>D3PZN1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019139.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3913"/>
    <dbReference type="EnsemblBacteria" id="ADD43568">
        <property type="protein sequence ID" value="ADD43568"/>
        <property type="gene ID" value="Snas_3913"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3913"/>
    <dbReference type="eggNOG" id="COG2153">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056607_3_1_11"/>
    <dbReference type="OMA" id="VVEQDCV"/>
    <dbReference type="OrthoDB" id="1777515at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="142" mass="16163" checksum="36DAEB68F2393EE8" modified="2010-04-20" version="1">MFTISSALFIELDLWVLYGVLRLRTDVFVVEQKCPYPELDGRDTEPQTRHVWATENDRVVAYLRITAEPDGFRVGRVCTEAASRGQGLAGKLVETALIHTGETPVWMHAQVSVVPFYERYGFAVQGPQFLEDDIPHVLMRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZQ8</accession>
    <name>D3PZQ8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid/peptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3942</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Membrane</location>
            <topology evidence="1 4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019166.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3942"/>
    <dbReference type="EnsemblBacteria" id="ADD43595">
        <property type="protein sequence ID" value="ADD43595"/>
        <property type="gene ID" value="Snas_3942"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3942"/>
    <dbReference type="eggNOG" id="COG3104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004790_0_2_11"/>
    <dbReference type="OMA" id="QMMGVWF"/>
    <dbReference type="OrthoDB" id="470322at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="term" value="F:peptide transmembrane transporter activity"/>
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        <property type="entry name" value="MFS_DtpA_like"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
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        <property type="entry name" value="MFS_trans_sf"/>
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        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
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    </dbReference>
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        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
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        </location>
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            <begin position="155"/>
            <end position="174"/>
        </location>
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            <begin position="180"/>
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        </location>
    </feature>
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            <end position="246"/>
        </location>
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            <end position="279"/>
        </location>
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    </feature>
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        <location>
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            <end position="358"/>
        </location>
    </feature>
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        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
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        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="466"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ADD43595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="496" mass="52666" checksum="5D2ADC383F61BBD3" modified="2010-04-20" version="1">MTEGTTTASNDRSFFGHPWALATLFSTELWERFSFYGMRAILVLFLTASVANGGWGWAAGDANALYGVYNGFVYLMALPGAWIADRLIGARRSVLWGGVIIALGHYSLALPWQPTFFLGLVLIVCGTGLLKPNMSAMVGELYPRDDPRRDAGFSLFYMGINIGGFVAPLITGYLAGNVGWHMGFAAAGVGMTIAVIWYVVGGRGMGDLGREVVKPLVEGESAKLVRNVLIGGVLSIAACVAAVWVLTDVAGMGSSTAILLVITFVPIIVAVVYFVRMFADPGMTSVERSRVHAYVYLFVFAAAFWLIYDQAGSVINLFTEKDVDLDLPLVGQVSAAMLQSINPILIIIGSPLAAIVWLRLGHRLSTPVKFCFGLIFNGVAFILMSFAAMAAVGGEKVSPLWIVAVYAIQVAGELSLSPVGLSATTKLAPAGYLSQMLGLWFLANAVGDAIGGQVARLQGPLGDPGYFSILGGASLALGLFAVLFARALRSLMRGIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZU3</accession>
    <name>D3PZU3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_3978</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ADD43630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3978"/>
    <dbReference type="EnsemblBacteria" id="ADD43630">
        <property type="protein sequence ID" value="ADD43630"/>
        <property type="gene ID" value="Snas_3978"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="OMA" id="VMVPQDG"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:ABC-type transporter activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
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        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
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        <property type="entry name" value="ABC_transporter-like_CS"/>
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        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ABC_tran"/>
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    </dbReference>
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        <property type="entry name" value="AAA"/>
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    </dbReference>
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        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="30"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="349"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="382"/>
            <end position="389"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="590" mass="62899" checksum="04A1E9EF994B10F9" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZU8</accession>
    <name>D3PZU8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3983</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019206.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3983"/>
    <dbReference type="EnsemblBacteria" id="ADD43635">
        <property type="protein sequence ID" value="ADD43635"/>
        <property type="gene ID" value="Snas_3983"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3983"/>
    <dbReference type="eggNOG" id="COG1126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="APIWVRR"/>
    <dbReference type="OrthoDB" id="1191583at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="12"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="252" mass="27569" checksum="D137452D579B97F3" modified="2010-04-20" version="1">MEKPTDASTPLVRLSGVNKHFGSNHVLKDINLHVDRGEVIVLIGPSGSGKSTLCRTINRLETIDSGTITVDGKPLPAEGRELAKLRSDVGMVFQHFNLFAHLTVLQNITLGPIKVRRQSKAAAEKRGRELLERVGLADKADALPAQLSGGQQQRVAIARGLAMDPKLMMFDEPTSALDPEMINEVLDVMQDLAREGMTMVVVTHEMGFARRASNRVIFLADGAIVEEAPPAEFFDNPQTERAQDFLSKVLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0A5</accession>
    <name>D3Q0A5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SIS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6008</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PGI/PMI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6008"/>
    <dbReference type="EnsemblBacteria" id="ADD45634">
        <property type="protein sequence ID" value="ADD45634"/>
        <property type="gene ID" value="Snas_6008"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6008"/>
    <dbReference type="eggNOG" id="COG1737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059687_2_0_11"/>
    <dbReference type="OMA" id="QAYRRGC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05637">
        <property type="entry name" value="SIS_PGI_PMI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019490">
        <property type="entry name" value="Glu6P/Mann6P_isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10432">
        <property type="entry name" value="bact-PGI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="52"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="399" mass="40930" checksum="EF483EED96972B98" modified="2010-04-20" version="1">MAGVSGDRNADPARIDSEESLARLDPGGSLRAVASAGPQLREVGQLAAEADLAQLSEGGRPRAVVVAGVGTAARTGDILTTVAGPRCPVPVLAHRSAGIPGWVGAADVVIAVSASGRSPEALAAAEAGARRGARLVAIGAPDSPLQAVAERARAPYIPVPRRAPARLSLWALTVPVLLAGRACGMVRIAEADIAEAAARLDADAERCKPLNDSFVNPAKALALDLAGAIPVVWGSSPLAGVAARRFGDMLAANARYPVVSGELGEVGRGRVGLLDGVFGSLAEGERDIFADPDDQATDGGTRLRIVLLRDDGLENDEDNPPPDTRRADAVAELADRRGIRCDTFAAEGGSALERLASLIAVPDFASVYLALAHGLDPHSVPAVSEMKDFTQNFGEVSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0F5</accession>
    <name>D3Q0F5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0098"/>
    <dbReference type="EnsemblBacteria" id="ADD39819">
        <property type="protein sequence ID" value="ADD39819"/>
        <property type="gene ID" value="Snas_0098"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0098"/>
    <dbReference type="HOGENOM" id="CLU_1045499_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="266" mass="29684" checksum="9CBB3A4E9CE6ED95" modified="2010-04-20" version="1">MTLVERDLYANMADAEAETRRAINELRNEVRRAALGGHEPVKAVASATPRPPRELPAYEEQQQDDRRPRPVAQGSADPYSRAREEREPTSGYVAETTAVPRQRWEDDYPVSGYENEGRDRRSNRHGSGQAVEAWRAEAEPTTPSRGTSRRARGVENGWSDEVYNSGSQPRASRGNDADSGAQPRASRTNGSDPAGGRGRHYREPDELDGVIPSRHYREDDDSGEIPSRHTTGSTRRREYASGESRSRGDSRSGGSYMDTYYGDSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0K4</accession>
    <name>D3Q0K4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2045</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017311.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2045"/>
    <dbReference type="EnsemblBacteria" id="ADD41740">
        <property type="protein sequence ID" value="ADD41740"/>
        <property type="gene ID" value="Snas_2045"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2045"/>
    <dbReference type="eggNOG" id="COG1122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_86_7_11"/>
    <dbReference type="OMA" id="CHCVSGP"/>
    <dbReference type="OrthoDB" id="870493at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="250"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="294"/>
            <end position="301"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="482" mass="50530" checksum="A4974714205899EF" modified="2010-04-20" version="1">MAEVALSGFSWRHAGRASFAVRDVDLHIAHGERVLLLGASGAGKSTLLAALAGLLPLDSGEQLGEVRIDGAPAAESRDRVGIVFQDPETQLVMQRAGDDVAFGLENRGVPRSEIWPRVDAALATVGFGYGRDRDTTALSGGEQQRLALAGALASRPGLLLLDEPTANLDPGGAASVRSALRDALDSTDATMILVEHRVTEALPLVDRIVVLAAGGGVLADGAPDEVCRRHGDFLDAQGIWVPGYSPVPRARAANVGEALIAAEGLGIAYPDAVRPAVDGVDLAVHAGQITAVLGDNGSGKSTLAMALGGLTAPTSGRVLATDALTSDSPTSKPPHKWRAKVLSRRIGSVFQNPEHQFVASTVFDELAMGPRAAKLTEAAVRSRVEELLERLRLKHLAQANPFTLSGGEARRLSVATALANAPRLLIMDEPTFGQDRRTWDELVDLLVEQRDEGAGIVAVTHDPHVVACAADRVVHLAAGRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0M8</accession>
    <name>D3Q0M8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017335.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2070"/>
    <dbReference type="EnsemblBacteria" id="ADD41764">
        <property type="protein sequence ID" value="ADD41764"/>
        <property type="gene ID" value="Snas_2070"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2070"/>
    <dbReference type="eggNOG" id="COG2234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024336_2_0_11"/>
    <dbReference type="OrthoDB" id="1465483at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029514">
        <property type="entry name" value="Ape3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF17">
        <property type="entry name" value="PTHR12147:SF17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048141" evidence="1">
        <location>
            <begin position="20"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M28" evidence="2">
        <location>
            <begin position="96"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="309" mass="33296" checksum="D4D61079AD986619" modified="2010-04-20" version="1">MRASRFPLVAVLAVGFVAACSTAEPRPEGPPDIDVKRVAEHLERFDDIAEYNDGNRAAGTSGYAESAEYLATELEEAGFDVERQACEDCTDPEDVNVIAEWGSKAKGDTVMFGAHLDSVAEGPGINDNGSGSAVLLEVALRLADTDPDMSAPVRFAWWAEEEAGMIGSAYYVDNTYTTDLAVYYNLDMVASTNTGYFVTHMDTKYGKAYADYLDSVGVKAEAAEANCDCSDDQPFADDDVSTVYVNTGDEVEMTSAQAKRWDGEAGEVFDPCYHAACDEYPDNIDTDALNHNADATAHVLWAFAATAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0R6</accession>
    <name>D3Q0R6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017373.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2108"/>
    <dbReference type="EnsemblBacteria" id="ADD41802">
        <property type="protein sequence ID" value="ADD41802"/>
        <property type="gene ID" value="Snas_2108"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2108"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063440_1_2_11"/>
    <dbReference type="OMA" id="TPPWDEI"/>
    <dbReference type="OrthoDB" id="1706427at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="2">
        <location>
            <begin position="98"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="251" mass="27167" checksum="89E913278E2B50C6" modified="2010-04-20" version="1">MSREHSWNNPWGADMRETLRGMRRSHAEGDSSHGRGRGRGRGRHHSHHRGYGPPGMGGPWGGMPPMPPMPPFPPGFGGGRGFGHRGRKARRGDVRAAILSLLGEGPMNGYQVMQAIAERSQGGWRPSPGAVYPALQQLTDEGLVQPTGEGRKTLFELTEAGTAYIAEHADEVEAPWEAMTPQIDDDVVELMNLAQQSGTALMQVIQSAGPVGRAKARKLLEDGRRGLYQILAEGEPEPEAADDADEEPTQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0U2</accession>
    <name>D3Q0U2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ThiJ/PfpI domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019263.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4040"/>
    <dbReference type="EnsemblBacteria" id="ADD43692">
        <property type="protein sequence ID" value="ADD43692"/>
        <property type="gene ID" value="Snas_4040"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4040"/>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_5_11"/>
    <dbReference type="OMA" id="DAWYRLF"/>
    <dbReference type="OrthoDB" id="1421548at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="3"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="204" mass="21891" checksum="A526A39FD0E743F1" modified="2010-04-20" version="1">MTKSVHVAIYDTLADWEIGHITAHINNGEFQREPGQYQIVTVGETAEPITTMGGLRVTPDTTLDQVSAADSAMLILPGAATWVPEGNKAFRAKAREFAEAGVPVAAICGATFGMAAEGLLDERAHTSNAPQFLTMSGYKGASNYRDELAVTDGNLITASGIAPVHFAREVFALLGVYEPSVLESWYKLYGQQDPSGYFELMESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1C5</accession>
    <name>D3Q1C5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6081"/>
    <dbReference type="EnsemblBacteria" id="ADD45705">
        <property type="protein sequence ID" value="ADD45705"/>
        <property type="gene ID" value="Snas_6081"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6081"/>
    <dbReference type="HOGENOM" id="CLU_2036609_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049635" evidence="1">
        <location>
            <begin position="31"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="121" mass="12185" checksum="A5F66BA9DFAE2F6A" modified="2010-04-20" version="1">MRILSRIGIVSLFAIGAFLVAGAAAGEAEAAPPLKASVKLPGKVKVGQKIDVDITCLTIDTKAIIHVKGDDLSIGTILSLSGGKASLSVTIPAKAPKGKYDINLICAPSSTKASAVSSVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1I6</accession>
    <name>D3Q1I6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Magnesium transport protein CorA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">corA</name>
        <name evidence="8" type="ordered locus">Snas_0113</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Mediates influx of magnesium ions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015405.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0113"/>
    <dbReference type="EnsemblBacteria" id="ADD39834">
        <property type="protein sequence ID" value="ADD39834"/>
        <property type="gene ID" value="Snas_0113"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0113"/>
    <dbReference type="eggNOG" id="COG0598">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007127_0_2_11"/>
    <dbReference type="OMA" id="MVSVRIF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004488">
        <property type="entry name" value="Mg/Co-transport_prot_CorA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="SSF143865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="SSF144083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00383">
        <property type="entry name" value="corA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD39834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="378" mass="42352" checksum="3644683A85F3DC21" modified="2010-04-20" version="1">MSDFRGLAKRALRKTTGRRAHHEPKPPEAAAVERAPVPGSSLIDAAVYRDGRRVSTPSSLAETYREARSDPETMAWIGLYRPTPGELKSLAIEFDLHPLALEDALEAHQRSKLERYGDTLFVVLRAARYLDDDESVDFGELHIFVGPGFVITVRHGAAPDLAVVRKRMEAEPELLARGHEAVLYAIFDAVVDGYVPVVAGLQNDIDEIETEVFGGDPQVSRRIYELSREVVQFQRAVRPLSGMLRGLISGFEKYGIDEELRRYLRDVADHAVSVMEQVDSFRQALADILTVNATLVAQQQNAKMQEMTETSLAQNDEIKKISSWAAILFAPTLIGTVYGMNFDYMPETHWKVGYPMAIVAMAATCVTLYLIFKRRNWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1K6</accession>
    <name>D3Q1K6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0133"/>
    <dbReference type="EnsemblBacteria" id="ADD39854">
        <property type="protein sequence ID" value="ADD39854"/>
        <property type="gene ID" value="Snas_0133"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0133"/>
    <dbReference type="eggNOG" id="ENOG503287X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2048300_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048160" evidence="1">
        <location>
            <begin position="33"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="119" mass="12136" checksum="C1DC7B4976FEFD92" modified="2010-04-20" version="1">MGEEMRKSIKALTVAAVAAGIGAFALAGTAQAGPTGAEEAGTGKISILSDWCVGNWNGPVITGATANNTDTRDLCSGFGGSDADFKLGSNLCAVNWDWNDAAKVGVINSVKDYQLCHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1L9</accession>
    <name>D3Q1L9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015438.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0147"/>
    <dbReference type="EnsemblBacteria" id="ADD39867">
        <property type="protein sequence ID" value="ADD39867"/>
        <property type="gene ID" value="Snas_0147"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0147"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042432_6_0_11"/>
    <dbReference type="OMA" id="AGEWWRP"/>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="49"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="240" mass="26035" checksum="FF19082C9475E808" modified="2010-04-20" version="1">MVNRNDPRQYDELAEEWWKPNGAFAMLHWLAKSRCALIPEPARADAVLVDIGCGGGLNTKHVSGYRHIGIDLRQPNLRLAADHGLAAVRGDALRLPVADESADVVVAGEILEHVPDWRAAVAEACRILRPGGTLVVDTLADTWLCRFVAVTLAERMPGGPPPGIHDPALFVPPQALLSECAGFGVTLELWGLRPAALSLVRWLVRRRGEVPMITTRSKSILYAGRGVKHAHGSAHGRRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1V3</accession>
    <name>D3Q1V3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2126"/>
    <dbReference type="EnsemblBacteria" id="ADD41820">
        <property type="protein sequence ID" value="ADD41820"/>
        <property type="gene ID" value="Snas_2126"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2126"/>
    <dbReference type="eggNOG" id="COG0510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066396_0_0_11"/>
    <dbReference type="OMA" id="WDLAYAV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="23"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="247" mass="28359" checksum="41817B83F181B8D6" modified="2010-04-20" version="1">MVRLGDTVRRNTGPWTPAVHALLRHLDAAGFTGSPKALGIDEHGREVLSYLEGECGKYPLEPHWTTDEALNTVATMLRMYHDSQYGFRTPPGAVWRSFGPPPPDTEVVCHHDAAPHNVIWRPDGTLALIDFDLASPGARIYDVAYAAWTWVPLFSDRDSITLGWKNPDRPRRLRLFADAYGLSERDRYRFIRVIRKRIVDHIEGIRRMANQGDPAFVRIVRKGHLRRPMRDLKVLDHERYILDHALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1X5</accession>
    <name>D3Q1X5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PASTA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2148</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2148"/>
    <dbReference type="EnsemblBacteria" id="ADD41842">
        <property type="protein sequence ID" value="ADD41842"/>
        <property type="gene ID" value="Snas_2148"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2148"/>
    <dbReference type="HOGENOM" id="CLU_1721234_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51178">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="3">
        <location>
            <begin position="80"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="152" mass="15777" checksum="B02565398CF189DE" modified="2010-04-20" version="1">MSQVTPRPEDRPDRSGRTPLILAVVAVIAVVGAVLVLWSPWDGGGPEPAPSGSTSASKGPETSESEPEPSPSDSGKATDDAEVERVPTVIGMPVQLAYREVKDKFSDVRLVADANGAGEACVVFAQDPESGEHPRSTTVTLTYAGTESECGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q201</accession>
    <name>D3Q201_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Coenzyme PQQ synthesis D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017439.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2176"/>
    <dbReference type="EnsemblBacteria" id="ADD41868">
        <property type="protein sequence ID" value="ADD41868"/>
        <property type="gene ID" value="Snas_2176"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2176"/>
    <dbReference type="HOGENOM" id="CLU_163864_1_0_11"/>
    <dbReference type="OMA" id="KHVRIQY"/>
    <dbReference type="OrthoDB" id="2008640at2"/>
    <dbReference type="UniPathway" id="UPA00539"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018189">
        <property type="term" value="P:pyrroloquinoline quinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008792">
        <property type="entry name" value="PQQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022479">
        <property type="entry name" value="PqqD_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041881">
        <property type="entry name" value="PqqD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05402">
        <property type="entry name" value="PqqD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03859">
        <property type="entry name" value="PQQ_PqqD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0884">PQQ biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="88" mass="9940" checksum="1FDA26DDC1548BD7" modified="2010-04-20" version="1">MRSEHTRPRLRNGVMLSFDPVRDCHVVLFPEGVIVPNETAVEILRLCDGASSVSEITQALRDRFAGVCDSEVTAVIDRFADRRIVEWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q264</accession>
    <name>D3Q264_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2241</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017502.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2241"/>
    <dbReference type="EnsemblBacteria" id="ADD41931">
        <property type="protein sequence ID" value="ADD41931"/>
        <property type="gene ID" value="Snas_2241"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2241"/>
    <dbReference type="eggNOG" id="COG3021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049141_0_0_11"/>
    <dbReference type="OMA" id="YTAHLDY"/>
    <dbReference type="OrthoDB" id="395082at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048808" evidence="2">
        <location>
            <begin position="31"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="3">
        <location>
            <begin position="40"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="315" mass="33876" checksum="16829E92BE986409" modified="2010-04-20" version="1">MSPKLKRVAVATAAVAVAVTGLATASTAHAQDEAAELKVMSFNLWHGGSQVNDYRAKQVEFIKSTGADVITLQESSVTSARELAKALDWDYLQADADRGIISRYEIVDDTQQPSNAGFGVHIELDSGQRVAVWNAHLGYDPYGPYDACFDNMSVDEILEREAESGRTGQITDILADMRDDLANADQTPVLLTGDFNAPSHLDWTAATADSHCGYSDIPWPTSVKPAEAGLTDSFREANPDPAAVPGNTWSPVYPKHDGSTGADEPQDRIDYILYKGGLTVTDSQALVVGEPQPVPDHADNEWTSDHAAVLTTFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2B7</accession>
    <name>D3Q2B7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_4200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019421.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4200"/>
    <dbReference type="EnsemblBacteria" id="ADD43850">
        <property type="protein sequence ID" value="ADD43850"/>
        <property type="gene ID" value="Snas_4200"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4200"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_10_1_11"/>
    <dbReference type="OMA" id="MKVPSPG"/>
    <dbReference type="OrthoDB" id="1626282at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014276">
        <property type="entry name" value="2-oxoglutarate_DH_E2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02927">
        <property type="entry name" value="SucB_Actino"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="136"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="275"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="71"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="213"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="322"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="583" mass="59977" checksum="DAFD6DF25F5FE61B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2J2</accession>
    <name>D3Q2J2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4097 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019496.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4276"/>
    <dbReference type="EnsemblBacteria" id="ADD43925">
        <property type="protein sequence ID" value="ADD43925"/>
        <property type="gene ID" value="Snas_4276"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4276"/>
    <dbReference type="eggNOG" id="COG3595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081211_0_1_11"/>
    <dbReference type="OMA" id="GTTETHI"/>
    <dbReference type="OrthoDB" id="1059710at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4097" evidence="1">
        <location>
            <begin position="13"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="264" mass="26610" checksum="3BE9FBE8551D6F7B" modified="2010-04-20" version="1">MPEFACDGPISVNITLASGSCEVVAEDRANAVVTVTPHKNNSKSKEAAEKTSVDFRDNKLTVRAPDMTSWLLGGNAAIDVVVKVPVGSNVTTKSASASINYQGQLEVVSATTASGSITVEKATEASVNTASGDAHVIECVGAARGNTVSGDLQLDHVGGDVNAKSVSGDVRIGYAGGSLQGNSVSGDINVNSISTGHCRVKSVSGAVSIGIAPGTGVWMDVTSVSGNTSSDLAVGDMPAAAAANLELHVNTISGNIDLFRAQPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2P1</accession>
    <name>D3Q2P1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IIB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6169</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021363.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6169"/>
    <dbReference type="EnsemblBacteria" id="ADD45792">
        <property type="protein sequence ID" value="ADD45792"/>
        <property type="gene ID" value="Snas_6169"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6169"/>
    <dbReference type="eggNOG" id="COG0561">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044146_0_0_11"/>
    <dbReference type="OMA" id="IHEYIET"/>
    <dbReference type="OrthoDB" id="1374424at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="271" mass="28727" checksum="43EE9C359245E44C" modified="2010-04-20" version="1">MTPKLVVVDLDGTVVGYGNHRLAPSPTVVKALADVRAAGVPVAVATGRAIWDALPTIAALDLADGLVSTTHGAITYDLDAGRIVGRTPLDTVEAVRRFTEAEPKVAFAVERDEAGWYHTSNFNRDFESKWAEVVDRETLSAEPAVRLVARLSWVPYRHMAAPCPEADRLAATVGLDPALYQVEPGYNGWIDVGPAGVTKATGLAVIAEHYGVTAADTIVFGDAANDLPMFAWAGHSVALGQAHDVIKAAADEVAPSVTDDGVAHVLRRWFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2V6</accession>
    <name>D3Q2V6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021428.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6236"/>
    <dbReference type="EnsemblBacteria" id="ADD45857">
        <property type="protein sequence ID" value="ADD45857"/>
        <property type="gene ID" value="Snas_6236"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6236"/>
    <dbReference type="HOGENOM" id="CLU_1353940_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="202" mass="22869" checksum="4E6CE4065240EC7D" modified="2010-04-20" version="1">MTNLEVDRIEWMRIYTVTCPVCAAEGPWRLWTREANAGLVCAGCDLDWQHPLVYPAYIKARAERIAAGTDAELPPLEETIGWRPHAQTSAVDIYESDAVAAEYWSPWDRGTRWDVDWPDLWQADGIATKIDEVAAEDAGCDLVTARRLWWVEPEIVATAKEKLAEFTAGTRNRAQFYHGKLFPLIAESQRRHGDLAPDQLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3E8</accession>
    <name>D3Q3E8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017560.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2300"/>
    <dbReference type="EnsemblBacteria" id="ADD41989">
        <property type="protein sequence ID" value="ADD41989"/>
        <property type="gene ID" value="Snas_2300"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2300"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_457723_0_0_11"/>
    <dbReference type="OMA" id="GHSVQRT"/>
    <dbReference type="OrthoDB" id="1560944at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028208">
        <property type="entry name" value="Effector_pro_NleD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14891">
        <property type="entry name" value="Peptidase_M91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="594"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="739" mass="77143" checksum="404D323E5F15A99F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3G6</accession>
    <name>D3Q3G6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2320"/>
    <dbReference type="EnsemblBacteria" id="ADD42007">
        <property type="protein sequence ID" value="ADD42007"/>
        <property type="gene ID" value="Snas_2320"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2320"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077964_0_1_11"/>
    <dbReference type="OMA" id="GRNRYYR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="223" mass="23832" checksum="E95B3DAE904BA6A0" modified="2010-04-20" version="1">MAGIARLIGEPARTAMLDALLTGRALAAGELARVAGVAAATASEHLARMRSAGLVATVAAGRHRYYRLASPEVAQALEALALLAPSRPVTSLRQSRRNAALLTARTCYDHLAGRVGVGIHRWLLASGALTQTAAGLDLTDTGRDRLGELGIDVAAARMRRRVFARSCLDFTERQEHLAGALGAAICARLLSLDWLRHRDPGHRGLRVTDLGRRELAAHFDLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3K3</accession>
    <name>D3Q3K3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2358</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017615.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2358"/>
    <dbReference type="EnsemblBacteria" id="ADD42044">
        <property type="protein sequence ID" value="ADD42044"/>
        <property type="gene ID" value="Snas_2358"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2358"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058006_0_0_11"/>
    <dbReference type="OMA" id="YDYIGRI"/>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048844" evidence="1">
        <location>
            <begin position="31"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="186"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="323" mass="34695" checksum="EE8224E61D40655A" modified="2010-04-20" version="1">MKRGKYRTLLACGTVFALALTGWGASVALADDADVKKAVADALMDAKADQARTAYGLSTEAGLETLVEPKRTSADGEWVFGGGVFLVPKDSHASPVTSLFFARDGGDGWQVALKGTREFAEAARQAPGEILIDEGERKALAATAKPAARPYDQREPTGLALPWAQGQGDWRHWGVHGNSGTSRPYNSIDFYGGDGQVRASAGGYLYRYCGTDTPLIEVEHGNGWTTGYYHTVEQTDVTDGAQVAAYDYIGRIGEQLPCGGSANGDHVHWTLWSGGEPVGVDGKDIGGWTWREEPEAYKGWAERDGEQIYNSDCCLTNHGPSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3V1</accession>
    <name>D3Q3V1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019589.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4371"/>
    <dbReference type="EnsemblBacteria" id="ADD44018">
        <property type="protein sequence ID" value="ADD44018"/>
        <property type="gene ID" value="Snas_4371"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4371"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_59_0_11"/>
    <dbReference type="OMA" id="PWLRYRN"/>
    <dbReference type="OrthoDB" id="871215at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="215"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="307" mass="33649" checksum="A42A17144F7437C6" modified="2010-04-20" version="1">MPRIVFVLVPRLHLLDLAGPAQVFSTAADLGHGWRLHYVAEHTEIHTAQGVPVRAELDWPSLGPADLVMVPGWRSPPLTDGPAVTEATAERLREHHRRGGTIASVCSGAYVLGQAGLLDGRRCTTHHALQDDLAKRFRRAEVVRDVLWVEDARVVTSAGIASGIDLALHLIAVRHGPAVAARVARQLVVFARRNGDAAQESVMLRHRSHLSDVVHRVQDLIDERYSQNLRLEDLAAYGGVSTRTLTRSFAEATGLTPLRYQQSLRTERATHLIASGSSVESAARQVGFADARMLRRLRSRLEAAKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q456</accession>
    <name>D3Q456_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="3">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6323</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6323"/>
    <dbReference type="EnsemblBacteria" id="ADD45941">
        <property type="protein sequence ID" value="ADD45941"/>
        <property type="gene ID" value="Snas_6323"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6323"/>
    <dbReference type="eggNOG" id="COG0212">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066245_1_0_11"/>
    <dbReference type="OMA" id="GIVFDFA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006806">
        <property type="entry name" value="FTHF_cligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02727">
        <property type="entry name" value="MTHFS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="113"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="178" mass="18339" checksum="704AF736222DCEC2" modified="2010-04-20" version="1">MSATDLDIAARTVLAALLAGLRLPAGSTVAAYSPVATEPGGKLTRALSGAGHRVLLPVVLPDLDLDWAEYTGKQHLTAKGLSEPDGPTLGTDAVAQVDALVVPALAVDTDGVRLGKGGGCYDRALTRVGPGVPVVALLHDGEWPRMVPREPHDRPVTAVVTPSGGYVNLGTRTRPRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4C6</accession>
    <name>D3Q4C6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015657.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0369"/>
    <dbReference type="EnsemblBacteria" id="ADD40086">
        <property type="protein sequence ID" value="ADD40086"/>
        <property type="gene ID" value="Snas_0369"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0369"/>
    <dbReference type="eggNOG" id="COG0631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067299_0_0_11"/>
    <dbReference type="OMA" id="HPGRANE"/>
    <dbReference type="OrthoDB" id="1359757at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="270" mass="29158" checksum="7044A4B9848A7535" modified="2010-04-20" version="1">MRVTGVSTPTRPFRDNEDWLGSGPGVVVVLDGCGQPDNIAEDTERGCAHGLPWYVKTLGTAVLRSAGDLATPLDDALATAIAETATAHHGRCDLHHPSTPASTVVILRENRRTVEYLVLGDSTIAIDDGSPEPIVVTDDREIRIPFPSIGSDEEQAKRNTREYMAVVEKLRNQPDGFPIAAADPQAAYRALAGHLGTEQVRRAIVASDGATRLVDRFGILTWTELLDLASSGGPEEVINQTRTAETTDLECKKWPRGRAHDDATLALCVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q529</accession>
    <name>D3Q529_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glyco_trans_4-like_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4433</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019649.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4433"/>
    <dbReference type="EnsemblBacteria" id="ADD44078">
        <property type="protein sequence ID" value="ADD44078"/>
        <property type="gene ID" value="Snas_4433"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4433"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1359707_0_0_11"/>
    <dbReference type="OrthoDB" id="635734at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="3">
        <location>
            <begin position="16"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="201" mass="20745" checksum="2034D3E84E1F5112" modified="2010-04-20" version="1">MAGRRIALVCAGEEVIGEHVATVAKGLKDAGDRVVVVAPSGFAASYGLDEAGVRFATLEIPPAAELVGDAKATWNLRAMLGGGAGRGPDVVHAFGTRAGLAAALSKVNSVPLVVTWWSELAEPGTGWQDRLRDQPTRLIARRGDVALCASTDLVSAVLRLGARDARHVGVPVTETVAAGGSASGTEPVEQLDALYRELTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q573</accession>
    <name>D3Q573_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sodium/hydrogen exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4477</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019693.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4477"/>
    <dbReference type="EnsemblBacteria" id="ADD44122">
        <property type="protein sequence ID" value="ADD44122"/>
        <property type="gene ID" value="Snas_4477"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4477"/>
    <dbReference type="eggNOG" id="COG0475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005126_4_0_11"/>
    <dbReference type="OMA" id="EDKGDMQ"/>
    <dbReference type="OrthoDB" id="941006at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="268"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="15"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="400" mass="41209" checksum="9D8661EF1EFCCA35" modified="2010-04-20" version="1">MGHAETLLAMGGAFVAAAVIARLGRRIGLPTIPLFMVAGILLGPYTPGFVLVDDPHEFEMLSALGLVLLLFYLGLEFHVDDLKKGGRKLFAVGGIYLLLNVGAGLGFGFALGWGTREALVLAGIVGISSSAIVTKLLVDTGRLGNPETRLILGIIVVEDIFLALYLAAIQPILGGAEGAAEMLWQMGKAFGFLLVLAIAARFGTRLIGKVIAVKDDELLVISFLGAAVLIAGISEKLGVADAIGAFMIGLILGGTTSGPRIRELVHPLRDAFGAIFFFVFGLSIDPGDIAVVAGPVAIAVGITIVGNLAAGIAAARMNGFGALPAANIASTLLARGEFALILGTMAAAAGLDERLTPFIAGYVLILAIIGPLSAGITEWLVPRLGLHPGDEAKIPRHAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5L8</accession>
    <name>D3Q5L8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycerophosphoryl diester phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6463"/>
    <dbReference type="EnsemblBacteria" id="ADD46078">
        <property type="protein sequence ID" value="ADD46078"/>
        <property type="gene ID" value="Snas_6463"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6463"/>
    <dbReference type="eggNOG" id="COG0584">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030006_3_0_11"/>
    <dbReference type="OMA" id="ETKHPTR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD46078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="236" mass="25957" checksum="919BFED92F025EB1" modified="2010-04-20" version="1">MVAHRGANVNLPEQSLAAYVEAIDVGADAIECDVRLTKDGHLVCHHDRTINRTSDGKGAIAELTLAELQKFNFARKNAPASEHHQILTFEALLRLISEAPRTITMLIEAKHPSRYGARIEHALHESLAKFPGLDVIVMSFARAAVTRYRTLDAEVPLVWLFEYPVGGPPPGATILGPRIDVLRAKPRLIERAHAAGQRVFVWTVNTPEQVKYVRDAGADAIITDDPAMVLRALGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5M3</accession>
    <name>D3Q5M3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Homogentisate 12-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6468</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the homogentisate dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021654.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6468"/>
    <dbReference type="EnsemblBacteria" id="ADD46083">
        <property type="protein sequence ID" value="ADD46083"/>
        <property type="gene ID" value="Snas_6468"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6468"/>
    <dbReference type="eggNOG" id="COG3508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053101_0_0_11"/>
    <dbReference type="OMA" id="PYNHSNI"/>
    <dbReference type="OrthoDB" id="193687at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004411">
        <property type="term" value="F:homogentisate 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006570">
        <property type="term" value="P:tyrosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005708">
        <property type="entry name" value="Homogentis_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056">
        <property type="entry name" value="PTHR11056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04209">
        <property type="entry name" value="HgmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD46083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="394" mass="44002" checksum="075330D90E9751F2" modified="2010-04-20" version="1">MPYYRAVGELPPKRHTQFRQPDGSLYAEELVGQEGFSSDSSLLYHRHLPTAISASTQHFPTAAAPEPNHPLKPRHLRTHKLDGGGDPILDRQHLLSNADCRISYAMSTQASVLYRNNLGDECLYVEDGAARVETSFGVIDIVSGDYLIMPMSTIYRIVPTGDTPLRTLVVESTGHITPPKRYLSVRGQFLEHSPYCERDIRGPSEPLVVDGENVDVYVQHRGRGAATIWTKFTYAHHPFDVVGWDGHMYPWVFSIHDFEPITGRIHQPPPVHQTFQGPNFVICSFVPRKVDYHPDAIPVPYNHHNVDSDEVLFYTGGNYEARKGSGIEQGSISLHPSGFTHGPQPGAPERAIGADYFDELAVMVDTFRPLELCEGALACEDSGYAWTWNRTPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q617</accession>
    <name>D3Q617_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="7">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">trpB</name>
        <name evidence="9" type="ordered locus">Snas_2510</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TrpB family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017763.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2510"/>
    <dbReference type="EnsemblBacteria" id="ADD42192">
        <property type="protein sequence ID" value="ADD42192"/>
        <property type="gene ID" value="Snas_2510"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2510"/>
    <dbReference type="eggNOG" id="COG0133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016734_3_1_11"/>
    <dbReference type="OMA" id="GPEHAMF"/>
    <dbReference type="OrthoDB" id="912282at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="8">
        <location>
            <begin position="58"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="406" mass="43455" checksum="CF51688F26B6ED56" modified="2010-04-20" version="1">MTEPVTGPDARGHWGQFGGRFVPEALVAALDELDAAYRKAMADETFTAEFDRMLREYANIPSPLYHAERLSREVGVRVLLKREDLNHTGAHKIRNVLGQALLTKRLGKNRIIAETGAGQHGVASATAAAYLGLDCTVYMGAEDCRRQALNVARMKMLGAEVIPVTAGSQTLKDSINEALRDWVSSVDNTHYLLGTAAGPHPFPVLVRDLVSGIGREARAQCLDMIGRLPNAVTACVGGGSNAMGIFHAFVPEESVALYGFEAGGKGLDTGKHAARLVVGNQGVLHGARSYLMQDDDGQIIESYSISAGLDYPSVGPEHAWLKESGRATYEAVTDAEAMDAFQRLCRTEGIIPALESAHALAGALRLAPVLRERHGDDAVVMVNLSGRGDKDMETAATYFGLTEDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q665</accession>
    <name>D3Q665_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017811.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2560"/>
    <dbReference type="EnsemblBacteria" id="ADD42240">
        <property type="protein sequence ID" value="ADD42240"/>
        <property type="gene ID" value="Snas_2560"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2560"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_7_2_11"/>
    <dbReference type="OMA" id="HPQMIAQ"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041478">
        <property type="entry name" value="TetR_C_27"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17935">
        <property type="entry name" value="TetR_C_27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="196" mass="21638" checksum="061605FF1A2C2EC3" modified="2010-04-20" version="1">MKPSGPLTSDRILEAAEDVLRRFGPDKTTVVDVARQLGVSHGSVYRHFPSKVALRDAVAERWLDRISRPLADIAARSGPAADRLREWMLRLATAKRELAGSDPELFATYFRLTSESRGVGAAHEEHLARQLSGIIADGVRAGEFTVDDPERSGWAVFRASARFNHPLHAAEWNRPGFEADLADLCDLLLRGLKTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6A1</accession>
    <name>D3Q6A1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Riboflavin synthase, alpha subunit</fullName>
            <ecNumber evidence="4">2.5.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2597</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.9" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017847.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2597"/>
    <dbReference type="EnsemblBacteria" id="ADD42276">
        <property type="protein sequence ID" value="ADD42276"/>
        <property type="gene ID" value="Snas_2597"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2597"/>
    <dbReference type="eggNOG" id="COG0307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034388_2_0_11"/>
    <dbReference type="OMA" id="HFVTGHV"/>
    <dbReference type="OrthoDB" id="1276859at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004746">
        <property type="term" value="F:riboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="PTHR21098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="93"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="93"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="193" mass="20730" checksum="C1E27CC018A83FC1" modified="2010-04-20" version="1">MFTGIVEELGEIVATAPASLSIRGKLITSDAHHGDSIAVNGVCLTVTAVTDDVFTVDVMGETYKRTALDTLKPGDQVNLERAATLSTRMGGHLVQGHVDAVGEILRREPEAEWETVTFRVPEALTKYIVEKGSITIDGVSLTVVAVKGEEFSVGLIPTTMQLTTLGRKRPGDPVHIETDIIAKHVEKLLEAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6E1</accession>
    <name>D3Q6E1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-aminoacyl-tRNA deacylase</fullName>
            <shortName evidence="1">DTD</shortName>
            <ecNumber evidence="1">3.1.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gly-tRNA(Ala) deacylase</fullName>
            <ecNumber evidence="1">3.1.1.-</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dtd</name>
        <name evidence="2" type="ordered locus">Snas_4539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glycyl-tRNA(Ala) + H2O = glycine + H(+) + tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DTD family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="1"/>
    <dbReference type="EC" id="3.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4539"/>
    <dbReference type="EnsemblBacteria" id="ADD44184">
        <property type="protein sequence ID" value="ADD44184"/>
        <property type="gene ID" value="Snas_4539"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4539"/>
    <dbReference type="eggNOG" id="COG1490">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076901_1_2_11"/>
    <dbReference type="OMA" id="GVFQAHM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051499">
        <property type="term" value="F:D-aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106026">
        <property type="term" value="F:Gly-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043908">
        <property type="term" value="F:Ser(Gly)-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00518">
        <property type="entry name" value="Deacylase_Dtd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="PTHR10472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="SSF69500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00256">
        <property type="entry name" value="TIGR00256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0820">tRNA-binding</keyword>
    <feature type="short sequence motif" description="Gly-cisPro motif, important for rejection of L-amino acids" evidence="1">
        <location>
            <begin position="135"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="15102" checksum="93D7325BBEA6B43A" modified="2010-04-20" version="1">MVGMRAVVQTVSQAAVTVDDETVGEISDGLLVLVGVTHDDTADDAAAMARKIWELRIMDGERSASDLGAPILVVSQFTLYADTRKGRRPSWGAAAPGPVAEPLVEAVIASLRELGAKVETGRFGAMMLVSSINVGPRTIILER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Z2</accession>
    <name>D3Q6Z2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Secretion protein snm4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0678</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EccD/Snm4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0678"/>
    <dbReference type="EnsemblBacteria" id="ADD40391">
        <property type="protein sequence ID" value="ADD40391"/>
        <property type="gene ID" value="Snas_0678"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0678"/>
    <dbReference type="eggNOG" id="ENOG502ZAY5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028325_1_0_11"/>
    <dbReference type="OMA" id="WIRFIPD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044049">
        <property type="entry name" value="EccD_transm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006707">
        <property type="entry name" value="T7SS_EccD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024962">
        <property type="entry name" value="YukD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19053">
        <property type="entry name" value="EccD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08817">
        <property type="entry name" value="YukD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017804">
        <property type="entry name" value="Secretion_EccD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03920">
        <property type="entry name" value="T7SS_EccD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="349"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="438"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="EccD" evidence="5">
        <location>
            <begin position="101"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="465" mass="48103" checksum="3EA4F7C9D9E22173" modified="2010-04-20" version="1">MAPITATGLCRVTVVAPHTRMDVALPVHVPIAEIQADLLLQAAASPNGEFFVNDGVKGGGWTLARLGEPPLNPDLSPAQLKLTDGEELYFRLAADTAPATVFDDVIDAIATAASHRAGKWQPSTSRKVGLVTGTLALAGGLVTAATMAGGLAGSIVLSAGVVALVACWALARAFEQHHAAVLLGLIGVGCGLFGGAILLIPAAEMSDLGAVHLLAGGCVGVVYSALAGLAAERSAPLFHSAAVACTGLILGTALRTWLEVPTQAAAATVAVLALAAIPMLPMLSYRLAQLPMPDIPRTPQQLRADLETLDGELALKRSARADDYLSGLLGACALMIGVSLPWLGAAETVSAFILCALLAFVVLLKARDFSTLRQRLPLIVAGLVGVGCLALAGGLWLEDGWRLGIVGGGLIAFAAFTILFSLVVAGKRISPVWGRTGDIVQIILTLAVLPITLWVWDAYWWIRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q788</accession>
    <name>D3Q788_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017930.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2682"/>
    <dbReference type="EnsemblBacteria" id="ADD42359">
        <property type="protein sequence ID" value="ADD42359"/>
        <property type="gene ID" value="Snas_2682"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2682"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_896903_0_0_11"/>
    <dbReference type="OMA" id="WRYCIAD"/>
    <dbReference type="OrthoDB" id="1540695at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038332">
        <property type="entry name" value="PPE_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="32192" checksum="09BB35D89ABDA5CD" modified="2010-04-20" version="1">MNDHSSDTDSSSRTGDVDTLIAYIEQTLTEIRSGGWSMGLTNGPKAASSEGVVADPIGSLSSSGFGWAAELFAPLQQAMNQLAGDPGKIQGFAQTWNDVGEQFSSQGRALRDTVATDGADWNSQAVSAYRGATDTESSAVEGAGNSFQGIGTAAQQGAQAVDAVRQDVTVLVNEAVTRAIPLLAQAMNPLGLAAAIAGLIELVAEYAPQIAKLLTDLANVMNSLGSLIGQLMPIISQALGLITTIAEAMSSASGGASGTEGTSTDQYQSSENDEYKPSEDEDQDDDEDDEEDEESSESPASQKDRDEVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q794</accession>
    <name>D3Q794_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017936.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2688"/>
    <dbReference type="EnsemblBacteria" id="ADD42365">
        <property type="protein sequence ID" value="ADD42365"/>
        <property type="gene ID" value="Snas_2688"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2688"/>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1085473_0_0_11"/>
    <dbReference type="OMA" id="TYETHER"/>
    <dbReference type="OrthoDB" id="1843667at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_12" evidence="1">
        <location>
            <begin position="50"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="256" mass="27817" checksum="2D0BF8DF531E7CCE" modified="2010-04-20" version="1">METVPDLTVTSDTDPYGAVAGLYDWLHVGPGSTDLVSFFAELAPEGGTGLEIGPGTGRMTLAVAPRLSSLYCLERSAFMRTILLTKLASLPELREKVTVLDEAVPGFSLGRTFDYVYVSAVFEHVPPDARQALFAGLAEHLAPGGIVAMDMVEDEVIPRFAEREIRSVRQGDCRYTLSTAVTPVQPDLGQVRHVYRTYLNDELLTTHTVEREHHMHRPAAVFADLRAVGLEPVAGTALTKTGTPLDDKGTLVAKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7J9</accession>
    <name>D3Q7J9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Intracellular protease, PfpI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C56 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019912.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4698"/>
    <dbReference type="MEROPS" id="C56.001"/>
    <dbReference type="EnsemblBacteria" id="ADD44341">
        <property type="protein sequence ID" value="ADD44341"/>
        <property type="gene ID" value="Snas_4698"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4698"/>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_4_11"/>
    <dbReference type="OMA" id="IGKYGVP"/>
    <dbReference type="OrthoDB" id="1421548at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006286">
        <property type="entry name" value="C56_PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42733">
        <property type="entry name" value="PTHR42733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01382">
        <property type="entry name" value="PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51276">
        <property type="entry name" value="PEPTIDASE_C56_PFPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="8"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="183" mass="19516" checksum="1D72D6CE545234D9" modified="2010-04-20" version="1">MTVTLEGRRVAFLVAPLGAEQVELTDPWQAVAEAGGSPVLVSTVSDNVQAFKHLDKADTFPVDEVVGETSADDYDALVLPGGVANPDFLRTDPLAVLFVSAFFAEDKPVAAICHAPWTLIEADVVRGRRLTSYPSLRTDLSNAGAEWVDEEVVVDGNLITSRKPADLPAFCDAMLRSVSDASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7M9</accession>
    <name>D3Q7M9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019942.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4729"/>
    <dbReference type="EnsemblBacteria" id="ADD44371">
        <property type="protein sequence ID" value="ADD44371"/>
        <property type="gene ID" value="Snas_4729"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4729"/>
    <dbReference type="eggNOG" id="ENOG50342C4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1585467_0_0_11"/>
    <dbReference type="OMA" id="YYLPWGP"/>
    <dbReference type="OrthoDB" id="1997138at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="18031" checksum="26BD0B3B2B14BEEE" modified="2010-04-20" version="1">MSGVYTDIDTLRRSRGLWFAVAVLLSMWLFGNVYEELVTIVAVLAEPRPGAFPDALEPGSPVFYYLPWGPLGVALTVVLRLRFGAAVSAKVRRTWNTALVALAIGVGAKVLLIVTVNPRFRDPSRSEMAVAADAVLWAFGNGLAIVGTATALALFALTRRPQPPAPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q832</accession>
    <name>D3Q832_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ResB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0825</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016108.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0825"/>
    <dbReference type="EnsemblBacteria" id="ADD40537">
        <property type="protein sequence ID" value="ADD40537"/>
        <property type="gene ID" value="Snas_0825"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0825"/>
    <dbReference type="eggNOG" id="COG1333">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023092_0_0_11"/>
    <dbReference type="OMA" id="RWFWRQL"/>
    <dbReference type="OrthoDB" id="1518243at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023494">
        <property type="entry name" value="Cyt_c_bgen_Ccs1/CcsB/ResB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007816">
        <property type="entry name" value="ResB-like_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31566">
        <property type="entry name" value="PTHR31566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05140">
        <property type="entry name" value="ResB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="ResB" evidence="7">
        <location>
            <begin position="27"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="522" mass="57626" checksum="75021D37328325C9" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q843</accession>
    <name>D3Q843_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="5">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP cyclohydrolase I</fullName>
            <shortName evidence="5">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">folE</name>
        <name evidence="7" type="ordered locus">Snas_0836</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0836"/>
    <dbReference type="EnsemblBacteria" id="ADD40548">
        <property type="protein sequence ID" value="ADD40548"/>
        <property type="gene ID" value="Snas_0836"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0836"/>
    <dbReference type="eggNOG" id="COG0302">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049768_3_3_11"/>
    <dbReference type="OMA" id="CEHMCMS"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="6">
        <location>
            <begin position="31"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="214" mass="23687" checksum="76B222E5CAD5C188" modified="2010-04-20" version="1">MNEELDHEAARIVNGRLGGKSVDTQVDLKRIETAVREILYAIGEDPDREGLAKTPGRVARAYAELFAGLRVDPAQVLKTVFSEDHDELIVVRDIEVFSFCEHHLLPFTGVAHIGYIPGAHGRITGLSKLARLVEAYARRPQVQERLTSQIADQLHETLEANGVIVVVECEHMCMSMRGIRKPGARTLTSAVRGILRDNAKSRAEAMSLINVSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q870</accession>
    <name>D3Q870_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2768</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2768"/>
    <dbReference type="EnsemblBacteria" id="ADD42444">
        <property type="protein sequence ID" value="ADD42444"/>
        <property type="gene ID" value="Snas_2768"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2768"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_38_2_11"/>
    <dbReference type="OMA" id="RASTHET"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="192" mass="20054" checksum="42E20889F200F417" modified="2010-04-20" version="1">MVRVNIRSGRRDLLEVAAEVLTTDPTASLGDVAAAAGISRTTLHSRYPKRDDLLLAVSRDAVARISEGIAEVGLPGADGTAAEHADGLRRLIATLVPLGARMHFLLRHSSADLDADLAANVAALDEPIDAFVREAQRAGVVKPELAPWWVISTLYSLTYAAWDGVAAGRLAPLDAPSQVFDTLLGGIGGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8G5</accession>
    <name>D3Q8G5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RTX toxins and related Ca2+-binding protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018110.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2864"/>
    <dbReference type="EnsemblBacteria" id="ADD42539">
        <property type="protein sequence ID" value="ADD42539"/>
        <property type="gene ID" value="Snas_2864"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2864"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_457723_0_0_11"/>
    <dbReference type="OrthoDB" id="676662at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028208">
        <property type="entry name" value="Effector_pro_NleD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14891">
        <property type="entry name" value="Peptidase_M91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="728" mass="76422" checksum="70CFF31BEC8C4A5A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8L0</accession>
    <name>D3Q8L0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="3 10">2.3.1.179</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Snas_4811</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:55040"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14074"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:83989"/>
            <dbReference type="ChEBI" id="CHEBI:138538"/>
            <dbReference type="EC" id="2.3.1.179"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 12">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="3 10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020023.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4811"/>
    <dbReference type="EnsemblBacteria" id="ADD44452">
        <property type="protein sequence ID" value="ADD44452"/>
        <property type="gene ID" value="Snas_4811"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4811"/>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_11"/>
    <dbReference type="OMA" id="QIGHCLG"/>
    <dbReference type="OrthoDB" id="606297at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="13">
        <location>
            <begin position="4"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD44452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="404" mass="41263" checksum="ED0FC2275B4EE52B" modified="2010-04-20" version="1">MTDVVVTGLGATTPLGGDVASTWRALVAGESGVGPLEQEWAAELPVRIAAQLAEDPGEKIPRVRQRRLDRSEQIAIIAATEAYADAGLTDAGLDPERLGVCYGSGIGGAITLLEQDDILEEKGARRVSPHTVPMLMPNGPAAWVGLELGAKAGVHAPTSACATSAEALAWGLDMIRLGRADVVVAGGCEAVVAPLPIAGFASMKALSTRNDDPTRASRPWDKGRDGFVLGEGAGAVVLERAEHAAARGARVYAKLAGAGITSDGFDIVQPDPAGGIRAMRAALRDADVAAADIGHINAHGTSTPVGDMGEIRGIVEAVGKHPIVTSTKSMTGHLLGGAGAVESIAIIKAIGEGIIPPTINLDDPDDDLVVDVAANTARKADISAAMNNSFGFGGHNVSLVFTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8T2</accession>
    <name>D3Q8T2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4883</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4883"/>
    <dbReference type="EnsemblBacteria" id="ADD44524">
        <property type="protein sequence ID" value="ADD44524"/>
        <property type="gene ID" value="Snas_4883"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4883"/>
    <dbReference type="eggNOG" id="COG0488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_0_11"/>
    <dbReference type="OMA" id="FKEYHRV"/>
    <dbReference type="OrthoDB" id="1112046at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="15"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="350"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="302"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="302"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="385"/>
            <end position="392"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="546" mass="59785" checksum="6BAC605BC0DE6760" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Y3</accession>
    <name>D3Q8Y3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016163.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0881"/>
    <dbReference type="ESTHER" id="stanl-d3q8y3">
        <property type="family name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40592">
        <property type="protein sequence ID" value="ADD40592"/>
        <property type="gene ID" value="Snas_0881"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0881"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_3_11"/>
    <dbReference type="OMA" id="YRWMVRS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="38"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="307" mass="33980" checksum="6D3B34BB6B5CAA29" modified="2010-04-20" version="1">MGRRSIDESTVLTDGPWKHRYVDANGVRFHVAEMGHGPLILLLHGFPEFWWAWHRQLPALADAGYRVAAVDLRGYGASDKPPRGYDAYTMASDITGLIRSLGEREAVLVGHDLGGMLAFAAAAFHPGSVRRLVILSAAHPLRQRAALAVDPRGQLSASRHILAFQLPRFEHVLTKNDAAMVGNLMRHWVGPDHADEAEFADYLRVCRDAIQLPQVALRALTAYRWALRSALLPSGRRFVKLLQEPIKAPTLQLHGSADTAVLPRTAQGSGRYVASSYEWRVLEGVGHFPQLEAPETVTGEILRWAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q976</accession>
    <name>D3Q976_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0975"/>
    <dbReference type="EnsemblBacteria" id="ADD40685">
        <property type="protein sequence ID" value="ADD40685"/>
        <property type="gene ID" value="Snas_0975"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0975"/>
    <dbReference type="eggNOG" id="COG3311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140176_13_0_11"/>
    <dbReference type="OMA" id="RIAPACI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="62" mass="7406" checksum="AF2A023E592D2833" modified="2010-04-20" version="1">MSRTRWFTVAEILADLKVPRRTWQQWRESGKTPTCKRLPNGQLRVSETNYNKWLESLEEVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q983</accession>
    <name>D3Q983_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018136.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2890"/>
    <dbReference type="EnsemblBacteria" id="ADD42565">
        <property type="protein sequence ID" value="ADD42565"/>
        <property type="gene ID" value="Snas_2890"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2890"/>
    <dbReference type="eggNOG" id="COG1129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_92_3_11"/>
    <dbReference type="OMA" id="AKREIYQ"/>
    <dbReference type="OrthoDB" id="551294at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="264"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="516" mass="57344" checksum="5822F4576D5FA20F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9A7</accession>
    <name>D3Q9A7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2914</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018160.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2914"/>
    <dbReference type="EnsemblBacteria" id="ADD42589">
        <property type="protein sequence ID" value="ADD42589"/>
        <property type="gene ID" value="Snas_2914"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2914"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_1_11"/>
    <dbReference type="OMA" id="VNVMAHV"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="258" mass="27177" checksum="665181732636CA90" modified="2010-04-20" version="1">MTVRQGAVVVVTGGGNGIGAALARRFAADKATVVVNDLDPDAAAAVAADIDGVAIAADAVHPEHLITEVRQRFGEIDLYCANAGVPAGGSEQAPDEDWDRAWQVNVMAHVRASRVLIGPWLERGRGHLLTTVSAAGLLTMLGAAPYSATKHAALAFAEWMTITYGDKGIRTQAICPLGVRTNMINDIGRYGEVLLEPAAIAPEAVADAVADALDDGPFLILPHPEVAKMYARRATDPDRWQTALRQIQSTIEADPAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9G2</accession>
    <name>D3Q9G2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4190 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2969</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018215.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42644">
        <property type="protein sequence ID" value="ADD42644"/>
        <property type="gene ID" value="Snas_2969"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2969"/>
    <dbReference type="eggNOG" id="ENOG5033A46">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1585463_0_0_11"/>
    <dbReference type="OMA" id="SCITAPI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025241">
        <property type="entry name" value="DUF4190"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13828">
        <property type="entry name" value="DUF4190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4190" evidence="3">
        <location>
            <begin position="83"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="18242" checksum="1F40EA90C979E6DF" modified="2010-04-20" version="1">MTYDPSAQQPDDPYTQYPDSPPPQQPTSGGYYPQQQPGYQQPGYQQPGYQQPGYQQSGYQQPAYQQTPGYMPEQELPQGMPLTSMILGIVSIPLVFCCYIGTITGILAIIFGAIGLSQVNKGEARGKGMAMAGLILGISAFVVLIVFIVLYIAVGASVGYDFNDYNSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9G7</accession>
    <name>D3Q9G7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UvrABC system protein C</fullName>
            <shortName evidence="6">Protein UvrC</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Excinuclease ABC subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">uvrC</name>
        <name evidence="12" type="ordered locus">Snas_2975</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with UvrB in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UvrC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2975"/>
    <dbReference type="EnsemblBacteria" id="ADD42649">
        <property type="protein sequence ID" value="ADD42649"/>
        <property type="gene ID" value="Snas_2975"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2975"/>
    <dbReference type="eggNOG" id="COG0322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014841_1_1_11"/>
    <dbReference type="OMA" id="HIECFDN"/>
    <dbReference type="OrthoDB" id="1036075at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00203">
        <property type="entry name" value="UvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004791">
        <property type="entry name" value="UvrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001162">
        <property type="entry name" value="UvrC_RNase_H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038476">
        <property type="entry name" value="UvrC_RNase_H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08459">
        <property type="entry name" value="UvrC_HhH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00194">
        <property type="entry name" value="uvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50165">
        <property type="entry name" value="UVRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 6" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="GIY-YIG" evidence="10">
        <location>
            <begin position="30"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="9">
        <location>
            <begin position="222"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="UVRC" evidence="11">
        <location>
            <begin position="275"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="638"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="225"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="651"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="671"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD42649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="708" mass="77931" checksum="99AD316B82D38BB4" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9K8</accession>
    <name>D3Q9K8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020125.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4913"/>
    <dbReference type="EnsemblBacteria" id="ADD44554">
        <property type="protein sequence ID" value="ADD44554"/>
        <property type="gene ID" value="Snas_4913"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4913"/>
    <dbReference type="HOGENOM" id="CLU_849700_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="35019" checksum="C3678AEC5CC577F2" modified="2010-04-20" version="1">MGDELQSKVDGILNQIPQYSSGDVESWAEKVKSAAKAKNGTTDYPYPDEYFEWIVPYFERFHQRMPSTAEAMVIELGVVREKILSAAPIIKAGTDKALTNWEGYAANSFTNFYIGAFTASPSCIDAQVAVIDELRAALWVYIGILKSMRSEAVEIAKATIATFESWDEWLWFGSDGQFLAGIAGAVATLFGVITATATAGVSLAIIGGAASASNAFIAKHRADEEASKKTIGGDTVADVLNNMADRLNELDTRCTDAEDAIATDLSSSVEAVGKILASDNATTLMRLVPNEIGDDNPLDAGQPGNTDTTDVTDPKDNPIPEFRPTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA38</accession>
    <name>D3QA38_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase domain protein TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016321.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1040"/>
    <dbReference type="EnsemblBacteria" id="ADD40750">
        <property type="protein sequence ID" value="ADD40750"/>
        <property type="gene ID" value="Snas_1040"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1040"/>
    <dbReference type="eggNOG" id="COG1082">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050006_6_3_11"/>
    <dbReference type="OrthoDB" id="1007505at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="250" mass="26202" checksum="16E93E04BAE206A7" modified="2010-04-20" version="1">MRSFGFSTLGCPGLDVDTVLAMARRHGADLVQLRCAPDEPVNTGLSGAGRADVVAAFATAGVGFGALATYVKLSDPDMLRPLDEHIALAVDLGAPALRLFPGDVAVETGTERLHRAEELAAGTGVVLTVETHDEYLRGAQIAQLLAETEAVKAVWDVLHTWRAGETVANSLAALGPYLAELQIKDVPSAEDRRPLAPGTGVLPLREALEAVAAAGIEVPVIFEHEAKWRADADPFEESLAAAVRLAKASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA57</accession>
    <name>D3QA57_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anion-transporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016340.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1059"/>
    <dbReference type="EnsemblBacteria" id="ADD40769">
        <property type="protein sequence ID" value="ADD40769"/>
        <property type="gene ID" value="Snas_1059"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1059"/>
    <dbReference type="eggNOG" id="COG0003">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058953_0_0_11"/>
    <dbReference type="OMA" id="EMPVQET"/>
    <dbReference type="OrthoDB" id="1148570at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="Anion-transp_ATPase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="PTHR10803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ArsA_ATPase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="322" mass="34124" checksum="1E7B8313A9E4C0CE" modified="2010-04-20" version="1">MPPEPAAERRTSPHVHVVTGKGGVGKTTVAAALAMALAPPGGRTLLVEVEGRQSIAPLFDTAPLPYAERHVATAPGGGEVFALAVDAEDALYDYLSMFYKLGRAGRALRKIGAIDFATTIAPGLRDILLTGKVKEAATRTDRGRRVYDAVVLDAPPTGRISRFLNVTVEASKLAKVGPIRNHSDGVAKLLHSPKKTAVHVVTRLEEMPVQETLDAVAELTALKLPVGHILVNAVSPPLLQGVRVTKAGLKRDLVTAGLPHDAGTVDGLVAEARDHQRRLAVQSELRGELTALDHPVVELPLQADGIDLSGLYTLAELLRSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAA8</accession>
    <name>D3QAA8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3020"/>
    <dbReference type="EnsemblBacteria" id="ADD42691">
        <property type="protein sequence ID" value="ADD42691"/>
        <property type="gene ID" value="Snas_3020"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3020"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_11_1_11"/>
    <dbReference type="OMA" id="GMMHAAG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045823">
        <property type="entry name" value="TetR_C_32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19344">
        <property type="entry name" value="TetR_C_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="27"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="213" mass="23787" checksum="610B0BC5F9627D9D" modified="2010-04-20" version="1">MADGGFVKTGDMDSVDGRKGRWQAHRQARRLELVQAAVRAIHRNGPHINMNDVAAAAKVTKPVLYRHFADQRELYHAVGQYAAEWLVAWLAQHLEPETEPTEVIATVIDAYLGAVETEPVLYRFVIRYAFADEANAVDGYRDIVVRHVDEMLRARLKAAGMDDSACHAWAQGIVGMVQSVGEWWLDRPDAATRPQLTQQLTALIWGGLSQAFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAC5</accession>
    <name>D3QAC5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3037"/>
    <dbReference type="EnsemblBacteria" id="ADD42708">
        <property type="protein sequence ID" value="ADD42708"/>
        <property type="gene ID" value="Snas_3037"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3037"/>
    <dbReference type="eggNOG" id="COG3576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085054_1_0_11"/>
    <dbReference type="OMA" id="CDVSPKG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024029">
        <property type="entry name" value="Pyridox_Oxase_FMN-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04025">
        <property type="entry name" value="PPOX_FMN_DR2398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="46"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="220" mass="24260" checksum="E61FB33A45E49FD9" modified="2010-04-20" version="1">MTETVDSQVTDGIEEVESAEELRQLIGNPNSRAASKERATLAPLDRQFLAASPFCLVATADAEGNCDVSPKGDPAGFTVVLDDSTIAIPERPGNKRADGFHNILSNPHVGLIYLLPGRGDTLRINGRARLVKNAPFFDRMVVKGHRPQFAVLVDIDAIYYHCAKAFMRSKLWRPETWQPDAMPSTAEIVKSVQPYIDESVADLERHYQTEVYSKGLYGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAD1</accession>
    <name>D3QAD1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018285.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3043"/>
    <dbReference type="EnsemblBacteria" id="ADD42714">
        <property type="protein sequence ID" value="ADD42714"/>
        <property type="gene ID" value="Snas_3043"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3043"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153137_1_1_11"/>
    <dbReference type="OMA" id="YHRAWTG"/>
    <dbReference type="OrthoDB" id="1836278at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="15"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="126" mass="13626" checksum="1D0C4E5D6C43F0A1" modified="2010-04-20" version="1">MTTDNASTGLEVALAYYEAWSGGDFDKAMTHLSPDLRALTPAGPISGAEAFREFMEPFTKRVTSIRLLAAYGEGDGALLMYDPATDIRDSAPGAEHHTVADGRIVELHLIFDRLPFELARRAAAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAL6</accession>
    <name>D3QAL6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3128</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018370.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3128"/>
    <dbReference type="EnsemblBacteria" id="ADD42799">
        <property type="protein sequence ID" value="ADD42799"/>
        <property type="gene ID" value="Snas_3128"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3128"/>
    <dbReference type="eggNOG" id="COG1129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="DNMFMGR"/>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="275" mass="29325" checksum="BC9D413024F48593" modified="2010-04-20" version="1">MTDTARMTARGLKKRYGHVTALDGTDFDLRAGEVLAVIGDNGAGKSTLIKALSGAIAPDAGTITLDGEPVRFRTPADARANGIETVYQDLALAPALDIATNMFMGRELRRKGPLGSVFRLLDKKRMRQQAAQHMSELQIGLQSLTHPVEDLSGGQRQGVAVARAAAWAEHVVIMDEPTAALGVKESAQVLDLIGRVRDRGLAVVLISHNMPHVFEIADRIHIQRLGKRVALVGREDHSMSEVVAIMTGALRVSDDDGEATEVVDQAAAAAAGLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAU8</accession>
    <name>D3QAU8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020315.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5109"/>
    <dbReference type="EnsemblBacteria" id="ADD44744">
        <property type="protein sequence ID" value="ADD44744"/>
        <property type="gene ID" value="Snas_5109"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5109"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108054_3_0_11"/>
    <dbReference type="OMA" id="HIPPRIH"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="3"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="110" mass="12132" checksum="7EF25184FC597A1F" modified="2010-04-20" version="1">MVTIGSIVLHVSDNIRAAEFWKGALGYVALPNNPDFLAPADGNGPRLHLDEDDRTHLDLYAADKREQEAEVERLISLGAKRVDWDYPDGADFVVLADPDGNLFCVIDTSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB84</accession>
    <name>D3QB84_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsC</name>
        <name evidence="13" type="ordered locus">Snas_1191</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016472.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1191"/>
    <dbReference type="EnsemblBacteria" id="ADD40901">
        <property type="protein sequence ID" value="ADD40901"/>
        <property type="gene ID" value="Snas_1191"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1191"/>
    <dbReference type="eggNOG" id="COG0092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058591_0_0_11"/>
    <dbReference type="OMA" id="KTNPIGN"/>
    <dbReference type="OrthoDB" id="1132353at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="12">
        <location>
            <begin position="38"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="209"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="209"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD40901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="265" mass="29413" checksum="3E2B4A10B9AF04A0" modified="2010-04-20" version="1">MGQKIHPHGYRLGISSGWTSRWYADKSYAEYVGEDVKIRKLMSQGMERAGIAEVDIERTRDRVRVDIHTARPGIVIGRKGAEADRLRTRLEKLTGKQVQFNIIEVKNPESNAQLVAQAIAEQLASRVNFRRAMRKSIQSALRNPTVKGIKVACSGRLGGAEMSRSEFYLEGQVPLHTLRANIDYGLFEARTSFGRIGVKVWIYRDEERAQARSSQDNVQRRRDDRGGRGERRGRVRSGASGTIGTGTEAGRAASTNAAANTGQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBU4</accession>
    <name>D3QBU4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5198"/>
    <dbReference type="EnsemblBacteria" id="ADD44833">
        <property type="protein sequence ID" value="ADD44833"/>
        <property type="gene ID" value="Snas_5198"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5198"/>
    <dbReference type="eggNOG" id="COG3568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060500_5_0_11"/>
    <dbReference type="OMA" id="YNVHSCI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049861" evidence="1">
        <location>
            <begin position="24"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="33"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="278" mass="30801" checksum="9A891DDEC78778E7" modified="2010-04-20" version="1">MKRLLPTLLLLAAFTFTVTPAQAHDRPTTLRVATYNIHAGAGSDNVFDVDRTAEAIASLDASVISLQEVDVHWHSRSQWRDLATELATTLDMHIFFGPIYSLDPTTPGAPRREFGNAILSSYPIVDAKNHEITRLSTQVPNPVPEPMPGFPEVEIDVNGTPVHVYSTHLDYRPDPAVRQAQVADMRRIMRCDHGEPQLLLGDFNAPPEAPELRPLWRKLSDVWAKSGQPDPGYTYPASAPDRRIDYIAASKRFKVKSAATPTTLASDHLPVVAELTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC29</accession>
    <name>D3QC29_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020489.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5284"/>
    <dbReference type="EnsemblBacteria" id="ADD44918">
        <property type="protein sequence ID" value="ADD44918"/>
        <property type="gene ID" value="Snas_5284"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5284"/>
    <dbReference type="HOGENOM" id="CLU_180396_2_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021375">
        <property type="entry name" value="DUF2997"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11211">
        <property type="entry name" value="DUF2997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="66" mass="7076" checksum="2B1272E49E28EE46" modified="2010-04-20" version="1">MAEETVEVVITPDGKVEVKVAGFAGTECLTATEALLRSLGGQVEEQTLTAEAYQDVEETRQHHTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU84</accession>
    <name>D3PU84_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016601.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1321"/>
    <dbReference type="EnsemblBacteria" id="ADD41030">
        <property type="protein sequence ID" value="ADD41030"/>
        <property type="gene ID" value="Snas_1321"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1321"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_0_11"/>
    <dbReference type="OMA" id="MREPIDL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="308" mass="32630" checksum="4DC768C1F1E1D13F" modified="2010-04-20" version="1">MLSVPALRLLHVLRLRGTVTAAAEQLRLSRSAASHQLASLQRSLGVPLTERVGRGLRLTEAGLRLAEHAGRVLAELEEAESAVERLRGAPAGTVRIGAVQVLAVNLLPGLLSRVRDSHAALRIEARSITTEDAMTAVSSGMLDVAVVPSYDLTPLTLEGGLTEVRLFRDPVRLALPSGHRLAGRESVAVAELAGEQWIGGDEDSYFGRLVPTLCRRAGFAPDVVHHSGDYAVVASFVAAGHGVAVIPASADLSTWPGVTVTVLDADDAGRDIVALLRTGSRDRPAVRAVVRELRRQAVAESLQRSVCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUK6</accession>
    <name>D3PUK6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Propeptide PepSY amd peptidase M4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3353</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018590.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3353"/>
    <dbReference type="EnsemblBacteria" id="ADD43019">
        <property type="protein sequence ID" value="ADD43019"/>
        <property type="gene ID" value="Snas_3353"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3353"/>
    <dbReference type="eggNOG" id="COG3182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031962_3_1_11"/>
    <dbReference type="OMA" id="QHTVYVD"/>
    <dbReference type="OrthoDB" id="1656356at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005625">
        <property type="entry name" value="PepSY-ass_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34219">
        <property type="entry name" value="PTHR34219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03929">
        <property type="entry name" value="PepSY_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="385"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="443"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="493" mass="53169" checksum="7F17508AE520D8DC" modified="2010-04-20" version="1">MSIPASPSPAAPTAPADAPVSPPPSRRAARRSIVPLLTRLHFYAGVLVAPFLAIAALSGLAFVFSPQLDDVVYADELYVDDIGETTQPLADQVAAAREAHPDGDLATVIPPVEPDETTKVVFSLPKLGEKQHTVYVDPYDNKVKGTLTTWFGETPLMTWLDDLHRNLHLGALGRHYSELAASWLWVIVLAGVFLWIRRQWTGRRKLRRTVLPDTNAGKGVRRTRSWHAATGIWLAVGLLALSATGLTWSRYAGGNFDIVQEQLSAQRPVLDTTLPGTDTGGEESGGGHHGSHTGNSGDAAYDPSNVDNVVEVARKAGLTGKIEVTPPTEAGTAWTVAQDDATWPVGYDQIAVDADTATVVSRNDFADWPLLAQLSKLGVAFHMGFLFGLINQILLAALAIGLLCVTVWGYRMWWQRRPTRTDRTAPVGAPPTRGTWRQVHPGAFAVGIGVVVFTCWAMPVLGVSLIAFLLFDAIAGLVRRSTVDAPRHTGDIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUX3</accession>
    <name>D3PUX3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5364"/>
    <dbReference type="EnsemblBacteria" id="ADD44997">
        <property type="protein sequence ID" value="ADD44997"/>
        <property type="gene ID" value="Snas_5364"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5364"/>
    <dbReference type="HOGENOM" id="CLU_518657_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038332">
        <property type="entry name" value="PPE_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="525" mass="55195" checksum="D3D9C0A06A31D31C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUZ9</accession>
    <name>D3PUZ9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5391</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5391"/>
    <dbReference type="EnsemblBacteria" id="ADD45023">
        <property type="protein sequence ID" value="ADD45023"/>
        <property type="gene ID" value="Snas_5391"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5391"/>
    <dbReference type="eggNOG" id="COG2020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065200_7_1_11"/>
    <dbReference type="OMA" id="WRIGVDD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="21738" checksum="C094EED692DB049F" modified="2010-04-20" version="1">MISVLAIVVFAAAFGLLFGVRSIQQTRRTGDVGWRFPSPGADRTQWIARLFMGFGGLTGGIAAPAAALMGMPSVTFMDHTWLRITGLVLAAVAAAAAFAAQQSMGASWRIGVDDTEHTALVTTGQFAYVRNPIFTAMFALMTNLALATPNIVAYIGLASVIAGIELQVRKVEEPHLLNTHPDTYRDYAQQAGRFLPGIGRLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV06</accession>
    <name>D3PV06_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5398</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020601.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45030">
        <property type="protein sequence ID" value="ADD45030"/>
        <property type="gene ID" value="Snas_5398"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5398"/>
    <dbReference type="HOGENOM" id="CLU_2156812_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="111" mass="11820" checksum="41860EB031B1B3A0" modified="2010-04-20" version="1">MKPKTTTVTVTGALAREPIARTTDTGGVVTSLRLVRVNSRALAHGVHITDATSMVDVEFDGELDPFWASFVDVGDPVHVTDATVIRPPAGSKAALLRTDIKSVSYRPSFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV84</accession>
    <name>D3PV84_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1431</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1431"/>
    <dbReference type="EnsemblBacteria" id="ADD41137">
        <property type="protein sequence ID" value="ADD41137"/>
        <property type="gene ID" value="Snas_1431"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1431"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_378082_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="19"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="467"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="482"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="547"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="619"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="654"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="684"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="733" mass="74309" checksum="7B00CF52ABE462E3" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVA7</accession>
    <name>D3PVA7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016731.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1454"/>
    <dbReference type="EnsemblBacteria" id="ADD41160">
        <property type="protein sequence ID" value="ADD41160"/>
        <property type="gene ID" value="Snas_1454"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1454"/>
    <dbReference type="eggNOG" id="ENOG503385K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180677_1_0_11"/>
    <dbReference type="OMA" id="IWQFAAT"/>
    <dbReference type="OrthoDB" id="2084295at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="89" mass="9999" checksum="D5696DC131084231" modified="2010-04-20" version="1">MTAYEWQEVIGVIGMFALLILVVTVTIWQIGATARTKAVLKQAEEHRALAETSFKAHAETREQLSELKDSVGDIQSRMANLERILKEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVH2</accession>
    <name>D3PVH2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018657.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3422"/>
    <dbReference type="EnsemblBacteria" id="ADD43086">
        <property type="protein sequence ID" value="ADD43086"/>
        <property type="gene ID" value="Snas_3422"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3422"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_5_3_11"/>
    <dbReference type="OMA" id="WFRALSD"/>
    <dbReference type="OrthoDB" id="1772343at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="110" mass="11677" checksum="8B0C4F7286E03B5E" modified="2010-04-20" version="1">MKEDDVAPLGKAEADEFAGWFRALSDGTRIQIVSLLAKRREPMKVGAIVEAVGVGQSTVSHHLKILAEVGFVLAQPSGASTLYRINESCVTAFPSAADVVMGRPAPPRIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVI9</accession>
    <name>D3PVI9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosidase PH1107-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3439</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 130 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018674.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3439"/>
    <dbReference type="EnsemblBacteria" id="ADD43103">
        <property type="protein sequence ID" value="ADD43103"/>
        <property type="gene ID" value="Snas_3439"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3439"/>
    <dbReference type="eggNOG" id="COG2152">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046648_0_0_11"/>
    <dbReference type="OMA" id="KYYMIWG"/>
    <dbReference type="OrthoDB" id="1622507at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007184">
        <property type="entry name" value="Mannoside_phosphorylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34106">
        <property type="entry name" value="PTHR34106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04041">
        <property type="entry name" value="Glyco_hydro_130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016202">
        <property type="entry name" value="PH1107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="319" mass="35051" checksum="A51BBCE216FCBBD7" modified="2010-04-20" version="1">MVQSESCLFRRHAEGPVLTASDWPYPINTVFNPGATSHEQETVLLCRVEDRQGVSHLTVARSRNGRTDWSIDPQPLIDADPDDPASCWGAEDPRVTRLEELGCWAITYTVYGPAGPAVALALTEDFRTLTPKGVILPPENKNASLFPRRVDGDFVLLHRPVSAASDTADIWLSRSSSLDSWTIAEPVLRSRRGPAWDAVRIGAGPPPIATSRGWLLVYHGVKAGAGTQVYRAGLALLDLERPERVLRRSTQWVLSPSTRYERQGDVPNVVFPTGMVHRLDTGDLDLYYGAADTSIGLATAKLDEVLDFLWDCEPVDNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVP1</accession>
    <name>D3PVP1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018726.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3492"/>
    <dbReference type="EnsemblBacteria" id="ADD43155">
        <property type="protein sequence ID" value="ADD43155"/>
        <property type="gene ID" value="Snas_3492"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3492"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056342_1_1_11"/>
    <dbReference type="OMA" id="DHWLGNH"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="35"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="315" mass="33910" checksum="6988C0B8D8985A68" modified="2010-04-20" version="1">MTIEPLSHDPVVDTGHAQELARDLVVIPNGGVGLVPNIGVIGGTRAVLVVETGLGPRNAEKVLGFAAEYAKGRELFLTTTHFHPEHAFGARTFADEATYLVNSAQAKNLTDKGQSYLEMFRGLGAPIARQLEGVELASPDVVYDEEYELDLGGRVVRMRATGRGHSLGDQVVTVPDADVLFTGDLAEAGQFAIFPWFPPYDVDVSGLRWIAVMRRLIATGPKVVVPGHGEVSGPRLLADVRDYLELLRDETWIRRDSAMPPDTIVAEVEALMIERYPQWAGQDWIAKGVGCLCAEHAEDDSPATSGVGRGGSVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVR6</accession>
    <name>D3PVR6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3517</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018751.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3517"/>
    <dbReference type="EnsemblBacteria" id="ADD43180">
        <property type="protein sequence ID" value="ADD43180"/>
        <property type="gene ID" value="Snas_3517"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3517"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_0_1_11"/>
    <dbReference type="OMA" id="GHTSFNW"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="10"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="155"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="333" mass="34645" checksum="5362797DA248BDAA" modified="2010-04-20" version="1">MNRSVSGDRALLTGILGAALISTSAVLVKLADLPATTTAALRTGYAVPVLALLAVIAWRRRPLPRDPRQRAWCLVAGVLFAGATLMQNLAVALIGAGIATVICNLQVLVVAVGAWWCFAERPPRRLLLALPPALLGVVMVSGMLGGQATGTDPSLGVLAGLANSLCYGAFLMVMRHAQRFGAAQPVAALRDVTAVAFAVSLLTVLAAGDGGMAPSWPAHGWMLLLALGPQVFGWLLITTNLPRLPLAVSGLLLLLQPMLTMGLAMVLLGENPSIVQLIGCVLLMTAVGFGAGTIVLPRPKGRQWLKSPSTSPRTRRFATTSSPGSPGSRRPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVS7</accession>
    <name>D3PVS7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5416</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5416"/>
    <dbReference type="EnsemblBacteria" id="ADD45048">
        <property type="protein sequence ID" value="ADD45048"/>
        <property type="gene ID" value="Snas_5416"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5416"/>
    <dbReference type="HOGENOM" id="CLU_213404_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027575">
        <property type="entry name" value="LD_lanti_pre"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04363">
        <property type="entry name" value="LD_lanti_pre"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="54" mass="5742" checksum="7A8AF9901DCBE8DD" modified="2010-04-20" version="1">MKPTLEATTDIEAFEDLFKLDVRIEAEGPSLSRCNPTNDGCSNSCTSVGCSANC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVS8</accession>
    <name>D3PVS8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lantibiotic dehydratase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5417</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5417"/>
    <dbReference type="EnsemblBacteria" id="ADD45049">
        <property type="protein sequence ID" value="ADD45049"/>
        <property type="gene ID" value="Snas_5417"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5417"/>
    <dbReference type="eggNOG" id="ENOG502Z81U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010573_0_0_11"/>
    <dbReference type="OMA" id="HLRLRFH"/>
    <dbReference type="OrthoDB" id="1149848at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006827">
        <property type="entry name" value="Lant_deHydtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023809">
        <property type="entry name" value="Thiopep_bacteriocin_synth_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14028">
        <property type="entry name" value="Lant_dehydr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04738">
        <property type="entry name" value="Lant_dehydr_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03891">
        <property type="entry name" value="thiopep_ocin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lant_dehydr_N" evidence="2">
        <location>
            <begin position="63"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="Lant_dehydr_C" evidence="3">
        <location>
            <begin position="727"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="968" mass="106293" checksum="5FD31EE35E2DDA3D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVT2</accession>
    <name>D3PVT2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020624.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5421"/>
    <dbReference type="EnsemblBacteria" id="ADD45053">
        <property type="protein sequence ID" value="ADD45053"/>
        <property type="gene ID" value="Snas_5421"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5421"/>
    <dbReference type="HOGENOM" id="CLU_2604356_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="79" mass="8870" checksum="EF4297E7F3C526AD" modified="2010-04-20" version="1">MTDTYDLHPEPEEFDDIPVTDDPELNRELLRAVLDGTDPAQIMQRVSKAGIVPPEPGRDDWAFAIIHEGNPETGTVIWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW06</accession>
    <name>D3PW06_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020698.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5496"/>
    <dbReference type="EnsemblBacteria" id="ADD45127">
        <property type="protein sequence ID" value="ADD45127"/>
        <property type="gene ID" value="Snas_5496"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5496"/>
    <dbReference type="HOGENOM" id="CLU_1757709_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="148" mass="15414" checksum="BA934B611B3AA1B0" modified="2010-04-20" version="1">MSQAREQDRWTPPESPYVSEGRDLAFDHGDVRQLARAMRTDATAFGGDIGKARAMLFGDMGFDTAPTFGVDPRNPRAAQMMKFHNAAFERAVGAADDHVAVGEAVGGAIGLAGAALSAADETAAEALDSVGGLLRDGLNLFTGDSEGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW66</accession>
    <name>D3PW66_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016794.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1519"/>
    <dbReference type="EnsemblBacteria" id="ADD41223">
        <property type="protein sequence ID" value="ADD41223"/>
        <property type="gene ID" value="Snas_1519"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1519"/>
    <dbReference type="eggNOG" id="COG1335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068979_13_2_11"/>
    <dbReference type="OMA" id="DFVDSWP"/>
    <dbReference type="OrthoDB" id="1442962at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="189" mass="19580" checksum="CB407A2CBAF10C3B" modified="2010-04-20" version="1">MARALIIVDVQNDFCEGGSLAVAGGASVAADISAMVAAEPGRWDRIVATRDRHIDPGRHFSTEPDFVDSWPPHCVVGTDGADFHPDLTVSPEAIFDKGAYSAAYSGFEGSAGEDDLAGWLRGHETTAVDIVGIATDHCVRATALDAAREGFDTTVLLDLTAGVAADTVETALTELRAAGVTLAGTPRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWM4</accession>
    <name>D3PWM4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018817.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43246">
        <property type="protein sequence ID" value="ADD43246"/>
        <property type="gene ID" value="Snas_3585"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3585"/>
    <dbReference type="HOGENOM" id="CLU_1991315_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="125" mass="13839" checksum="D361238C58708B4C" modified="2010-04-20" version="1">MNDATTHSVSVIVSRDHHRWAAEAPSISMWTFGRTLSQIHQHVTDAAALALDIHPEHVAVTLTVVSPELEELTRARAREQAALTAAVRRLRSQKVSWPETARILHVSQHEARAAVATASVEDNQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWP0</accession>
    <name>D3PWP0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lantibiotic dehydratase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3602"/>
    <dbReference type="EnsemblBacteria" id="ADD43262">
        <property type="protein sequence ID" value="ADD43262"/>
        <property type="gene ID" value="Snas_3602"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3602"/>
    <dbReference type="eggNOG" id="ENOG502Z81U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010573_0_0_11"/>
    <dbReference type="OMA" id="ITHVLAQ"/>
    <dbReference type="OrthoDB" id="1149848at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006827">
        <property type="entry name" value="Lant_deHydtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023809">
        <property type="entry name" value="Thiopep_bacteriocin_synth_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14028">
        <property type="entry name" value="Lant_dehydr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04738">
        <property type="entry name" value="Lant_dehydr_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03891">
        <property type="entry name" value="thiopep_ocin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lant_dehydr_N" evidence="1">
        <location>
            <begin position="45"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="Lant_dehydr_C" evidence="2">
        <location>
            <begin position="723"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="964" mass="104996" checksum="68E72F125386A904" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWR7</accession>
    <name>D3PWR7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3629</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43289">
        <property type="protein sequence ID" value="ADD43289"/>
        <property type="gene ID" value="Snas_3629"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3629"/>
    <dbReference type="eggNOG" id="ENOG5032ZA1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_499577_0_0_11"/>
    <dbReference type="OMA" id="CEYRIAW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="545" mass="59708" checksum="6F51582AC78D766E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWW4</accession>
    <name>D3PWW4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020759.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5557"/>
    <dbReference type="EnsemblBacteria" id="ADD45188">
        <property type="protein sequence ID" value="ADD45188"/>
        <property type="gene ID" value="Snas_5557"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5557"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_1_0_11"/>
    <dbReference type="OMA" id="MDLTIAY"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="3"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="371" mass="40827" checksum="F85A14EB130F4C13" modified="2010-04-20" version="1">MNHVLVSGASIAGLTTAHWLRRHGFTVTIVERAATLRPGGQAIDVRGVGLDVIREMGLLDEVRANVTGLRGMTIVDADGNVLTETHEETFSGGTIDNEDVELMRDDLTNILHSAVDEAVEFLFSNSIAELTPTETGVSVVFDSGRTGDFDAVVGADGLHSVTRKLAFGPESDYVRSLDGYVGIWTMPNFLNLDHWQMLQHLGDTTAVIYSGRKTEEMRAIIGFKSEKLDYDYRDAETHKQLLEKHFGGLGWEIPNLLRHMRSASDFYFDEMAQIHMDTWVDGRVGLVGDAGYCASPLSGQGTSLALVGGYVLAGELAASRDDLATGFTNYVGTMRPYVRVNQELAHLNRNGTATEPDRQHAYRALTLRDYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXA2</accession>
    <name>D3PXA2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1663</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016936.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1663"/>
    <dbReference type="EnsemblBacteria" id="ADD41365">
        <property type="protein sequence ID" value="ADD41365"/>
        <property type="gene ID" value="Snas_1663"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1663"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_993619_0_0_11"/>
    <dbReference type="OMA" id="LESCTYR"/>
    <dbReference type="OrthoDB" id="1919329at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="114"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="280" mass="30524" checksum="E19BCD9FC231D06C" modified="2010-04-20" version="1">MPRRTRLSDGDCAIAQSLDVVGEWWTLLVVRDVARGRHRFEELRAELGISRKVLTERLATLVDNGVLRRDRYSEHPPRHEYRLTELGHGLLPVLAALQDFGDRWLLGDGSLTATAEPGSAEAARMHALKGTAVPEVDGIDPIAATGLTVLYFYPATGLPHAASIPGGPGCTVESCTYRDRLDAFTALGATVHGVSTQRPEEQAAFARTNRIQFPLFSDAELRLATALRLPTFRAAGVRRIKRLTLIVDADRRIREVLYPIPDAGGSVADALAACRELVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXD8</accession>
    <name>D3PXD8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1702</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016972.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1702"/>
    <dbReference type="EnsemblBacteria" id="ADD41401">
        <property type="protein sequence ID" value="ADD41401"/>
        <property type="gene ID" value="Snas_1702"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1702"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_11_2_11"/>
    <dbReference type="OMA" id="IAMEYGE"/>
    <dbReference type="OrthoDB" id="1469881at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022324">
        <property type="entry name" value="Bacilysin_exporter_BacE_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01988">
        <property type="entry name" value="EXPORTERBACE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="402"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="42"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="438" mass="45672" checksum="A50B97212BA18B11" modified="2010-04-20" version="1">MSRCRNSVYHFAVPRGLTTEDPPQPSATGPSRAIVSLRASPRFRFLWVSNIFFFGGTWIQTLILGWLVFETTDSELLLAIFTAVRLTPMLLGPIAGVLSDRYDRVRLLTGACLLALGTVVALATLTSLGMAPYWVVLLGGLIIGLAHSPSQPARSSLVAELVGPENLSNANALNSMAMSLPQVVGPAIGGALISALGASWALWISTLWYVVSLLMLLPLRGSGRAAAVAHDGVLAMLTGGVRSILRNRLAATVLGITVVANILLWPIYQSFMPVFAKSTLGLDAAGLGWLLTCNGVGGLVGSIVIAAMGDFRFKGGVFVFGTALWGGLWSLFALSANVPLSFALLAGIGVASSFFGVLQTTLLLLTTEPAVQGRALGIQELAIGVMPIAALGLGAIAEVAGIGATTFVSALLLVAVMLVVAVRVPLLLRFSGTRAVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXL0</accession>
    <name>D3PXL0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3683</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3683"/>
    <dbReference type="EnsemblBacteria" id="ADD43340">
        <property type="protein sequence ID" value="ADD43340"/>
        <property type="gene ID" value="Snas_3683"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3683"/>
    <dbReference type="HOGENOM" id="CLU_752084_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="368" mass="39622" checksum="3882726538745DB0" modified="2010-04-20" version="1">MRTRLRHGLMIGLTLVLAGCGTGFGPIDFPKGQSTDLVDGALSELEKHPFLSFTGEVDDFVDGHDATVTIGISDAGLMYGTAKVGDAKLKLLSVDGKYFVNADTAFWKGYDHDEKQAKVLGGDWSPVDPKEFFDPGSVLATKMYVAALKSTLREVKAADSWRQEPTEKHGDRCYPLEVRDGTMCVTVDKPHRIIHLDDVPVTYKAGKSEHTAALDLELGALDTKAVKSWAKDLRAAVKDLSPVYAYGGVSMAMSSDGFFCSGTTCTFTALMGAEDLPKFQTVANKVKVGFKGVATTDSGQSQSCTATVTVKVGTSELADCSVTFSLRPGESQSVSAEYQSTGLMTFKPDTRDLGKQVKKDVKKILDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXP7</accession>
    <name>D3PXP7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome d ubiquinol oxidase, subunit II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3720</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018948.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3720"/>
    <dbReference type="EnsemblBacteria" id="ADD43377">
        <property type="protein sequence ID" value="ADD43377"/>
        <property type="gene ID" value="Snas_3720"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3720"/>
    <dbReference type="eggNOG" id="COG1294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049294_0_1_11"/>
    <dbReference type="OMA" id="FLWGVAF"/>
    <dbReference type="OrthoDB" id="761975at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000267">
        <property type="entry name" value="Cyt_oxidse_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00203">
        <property type="entry name" value="cydB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="334" mass="35677" checksum="EB0BBF1783CF104A" modified="2010-04-20" version="1">MDLPTVWFVLIAVLWTGYFVLEGFDFGVGTLMGVIGRDNPTRATMMGTIGPVWDGNEVWLIVAGGATFAAFPAWYATLFSGFYLPLLVILIALIVRAVGIEYRHKRDDIAWQRRWDACIIAGSILPSFLWGVAFANLTAGVPINADGNYAGTVFDLLGGYALLGGLTTLALFTTHGAVFLALKTTDPLRTTARRTAVRLGVVTIVAAAAFLTWTAFKHANPASIALSITAAVALVAAVALVAAGREGWSFSATTVTITAVVAALFTALFPDVMPSTIDSAYSLTVAGTASSPYTLKIMTIVAAIFTPVVLLYQGWTYWVFRKRLTAPRQADAHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXQ8</accession>
    <name>D3PXQ8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018959.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3731"/>
    <dbReference type="EnsemblBacteria" id="ADD43388">
        <property type="protein sequence ID" value="ADD43388"/>
        <property type="gene ID" value="Snas_3731"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3731"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098980_1_0_11"/>
    <dbReference type="OMA" id="RPDGWWK"/>
    <dbReference type="OrthoDB" id="1469203at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="132" mass="13923" checksum="B5876A75DAFA4B80" modified="2010-04-20" version="1">MAEDQVTPLIVVDAANVVGSRPDGWWRDRAGATARLRDRLAGLHEQGLRAGPDWARRPPLEIVLVTEGRARGVEASDTVGVVEAPGSGDDAIARLVAETTPHRQCLVVTSDRGLRRRVEAAGGQVTGAGTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXT8</accession>
    <name>D3PXT8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3761"/>
    <dbReference type="EnsemblBacteria" id="ADD43418">
        <property type="protein sequence ID" value="ADD43418"/>
        <property type="gene ID" value="Snas_3761"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3761"/>
    <dbReference type="eggNOG" id="ENOG5032VSD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1634066_0_0_11"/>
    <dbReference type="OMA" id="GHMEITR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007061">
        <property type="entry name" value="DUF664"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04978">
        <property type="entry name" value="DUF664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="165" mass="17928" checksum="6B2A1111A7E94AC8" modified="2010-04-20" version="1">MCSDDAATSSPQLSADDCLFFVDRALDQMVAIVTELGDTTANRSPDLPGANSPYQLLTHCLGVCEYWGGAMIAGRVVERDRAAEFTAEGPVEPLAQRVQAAKAQFRRDLASLRATAPTAAALPKHWNPTKAERTFTQGEALVHVVEELCQHLGHLEITRDILRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXV4</accession>
    <name>D3PXV4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020854.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5653"/>
    <dbReference type="EnsemblBacteria" id="ADD45283">
        <property type="protein sequence ID" value="ADD45283"/>
        <property type="gene ID" value="Snas_5653"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5653"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025711_1_2_11"/>
    <dbReference type="OMA" id="NYTIVHP"/>
    <dbReference type="OrthoDB" id="948454at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="222" mass="23565" checksum="42A95BFC7EB119AB" modified="2010-04-20" version="1">MKIFLIGAAGGIGRRLSPLLAHRGDEITGIHRDSAQTETVESSGATSLLGDLIADSTDELATKMRGHDAVVFSAGAHGTGQELTTLIDGIGLEKAAEAAAQASVPRFVLVSVFPDAGRDRERREGFEHYMKVKKTADVYLTRTDLDWLIVRPGTLRDEPGTGKVTAGPAIEYGDVPRDDVAAFIDAALHEPALTRTIVELTGGEVPISGAIRALLNGRPRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY98</accession>
    <name>D3PY98_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1768</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017036.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1768"/>
    <dbReference type="EnsemblBacteria" id="ADD41465">
        <property type="protein sequence ID" value="ADD41465"/>
        <property type="gene ID" value="Snas_1768"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1768"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="DECRIAR"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="907" mass="99032" checksum="25614047C3C70457" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ48</accession>
    <name>D3PZ48_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA 2',3'-cyclic phosphodiesterase</fullName>
            <shortName evidence="1">RNA 2',3'-CPDase</shortName>
            <ecNumber evidence="1">3.1.4.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 2'-phospho-ribonucleotide-RNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11828"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:17353"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:173113"/>
            <dbReference type="EC" id="3.1.4.58"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 2H phosphoesterase superfamily. ThpR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.58" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5848"/>
    <dbReference type="EnsemblBacteria" id="ADD45477">
        <property type="protein sequence ID" value="ADD45477"/>
        <property type="gene ID" value="Snas_5848"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5848"/>
    <dbReference type="eggNOG" id="COG1514">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081251_1_1_11"/>
    <dbReference type="OMA" id="AVRTSAW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004113">
        <property type="term" value="F:2',3'-cyclic-nucleotide 3'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008664">
        <property type="term" value="F:2'-5'-RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01940">
        <property type="entry name" value="RNA_CPDase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004175">
        <property type="entry name" value="RNA_CPDase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35561">
        <property type="entry name" value="PTHR35561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02258">
        <property type="entry name" value="2_5_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="HXTX 1" evidence="1">
        <location>
            <begin position="34"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 2" evidence="1">
        <location>
            <begin position="119"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="176" mass="18887" checksum="E24F2DB2B2F70CB6" modified="2010-04-20" version="1">MGLRPSDAALADLAGYLPRIGLDGARPTGRQTWHLTLAFIGELDDRRVEDVSAALTALSRTTAGFALRLAGGTVLGRTSTALCVGTDGDTTALTALAERVRTGLRRSGVPFDERPFKPHLTVARPKDLSPAEVQAKVDALGGYNGPSWRAEKLVLYRSHPGPPVRYEALERFPLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ60</accession>
    <name>D3PZ60_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cold-shock DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5860"/>
    <dbReference type="EnsemblBacteria" id="ADD45489">
        <property type="protein sequence ID" value="ADD45489"/>
        <property type="gene ID" value="Snas_5860"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5860"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125944_2_0_11"/>
    <dbReference type="OMA" id="QRVEFGM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="1">
        <location>
            <begin position="12"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="144" mass="16248" checksum="D6354855AB755D3B" modified="2010-04-20" version="1">MFLRFEYEVKAVPTGRVKWYNAEKGFGFVSRDDGGNDVFLHRDALPEGVTELKAGQKLEYGIVDTRRGVQAMSVTLVDTPKRVAKAEPQTPKRSPEEVHGLIEDMIKVLEDQVMPTLRRGRHPDRKHTAKIAEVVHAVARELEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ91</accession>
    <name>D3PZ91_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5892</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021091.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5892"/>
    <dbReference type="EnsemblBacteria" id="ADD45520">
        <property type="protein sequence ID" value="ADD45520"/>
        <property type="gene ID" value="Snas_5892"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5892"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_4_11"/>
    <dbReference type="OMA" id="HSEFVFM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="332" mass="34948" checksum="E37473B0D093CE16" modified="2010-04-20" version="1">MRARLSDIARHAGVSEATVSRVLNDRPGVGSATKQAVLTALDVLGYERPAALRQHSAGLIGLVVPELENPIFPLFAQVISTQLANNGYTPVLCTQSPGGVTEDEYVEMLRERRVAGIVFVSGLHADTTADVGRYQKLADGGLPLVFVNGYMDQLPSPCFSCDDGVAAKLGVEHLLSLGHRRIGLVSGPERFIPVQRKRAGYLAAIEGRAEPLVELTMFGVEGGAAAAARLLDSGATGILCGSDLMALGAIREARARGLSVPGDVSIVGYDDSPLIAHTDPPLTTLRQPVRPMALAAVRALLDEIAGHAAPSTEYLFRPELVVRASTGTAVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZE8</accession>
    <name>D3PZE8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arginase/agmatinase/formimino glutamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1926</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1926"/>
    <dbReference type="EnsemblBacteria" id="ADD41622">
        <property type="protein sequence ID" value="ADD41622"/>
        <property type="gene ID" value="Snas_1926"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1926"/>
    <dbReference type="eggNOG" id="COG0010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_6_2_11"/>
    <dbReference type="OMA" id="VMPAVDS"/>
    <dbReference type="OrthoDB" id="1598732at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782">
        <property type="entry name" value="PTHR43782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="295" mass="31019" checksum="AAD31BEC144041F1" modified="2010-04-20" version="1">MLDAPSNLGLRPPTPTTVPGCAKAPGALRDQGLVARLGARDAGCLTAPRFDTGDWQPGDGVSQAVEIAEYSRKLADRIDGILDEGEFPLVLGGDCSILLGAGVAMRRRAKARGGKCGLVFMDGHSDFRHPGNAPYVGAAAGEDLALVTGRGQPDLTDIDGLRPYFPPASTAVLGIRDGDAHRMELTATGIAHRTVPQLRSAGAIRSAEWAIDRLGDVGGFWLHVDVDILDSSVMPAVDSPDSGGIAHGELQQLIEVFTSYEECLGMELTVFDPDYDPDGEYAAAIVDTLVRGLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZM9</accession>
    <name>D3PZM9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019137.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3911"/>
    <dbReference type="EnsemblBacteria" id="ADD43566">
        <property type="protein sequence ID" value="ADD43566"/>
        <property type="gene ID" value="Snas_3911"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3911"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114564_0_1_11"/>
    <dbReference type="OMA" id="WHYEGEY"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="161" mass="17399" checksum="37C08AF5466E507E" modified="2010-04-20" version="1">MTSTWPKRLHIRPLTTADARDIADWRYGGDWSIYDSRPEDGLLQAADGYWAVTGAEDGSLVGFCCLGFDARVPGLVKAEGVEDLGVGMRPRFTGSGHGPAFAAAVVAFARAHSGKPRLRAVVQSWNTRSLRLFQSLGFVEDGVHVCVEGGREVEYTVLVCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZR0</accession>
    <name>D3PZR0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FxsA cytoplasmic membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3944</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019168.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3944"/>
    <dbReference type="EnsemblBacteria" id="ADD43597">
        <property type="protein sequence ID" value="ADD43597"/>
        <property type="gene ID" value="Snas_3944"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3944"/>
    <dbReference type="eggNOG" id="COG3030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085083_2_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007313">
        <property type="entry name" value="FxsA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35335">
        <property type="entry name" value="PTHR35335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04186">
        <property type="entry name" value="FxsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="205" mass="22094" checksum="1E97F160BCB23F9C" modified="2010-04-20" version="1">MTSPHEVPGQPRRPSYRARLTFAIYAAAELVTLYLLWTSIGPLWTILLFGATTVLGIVSLGAVGTKAARDYREAVSRNEPPGPAAISGTIGVVGAILLILPGFLTDVVGLLCVFPPTRFLWRSLVTRFVSKRMDSPSVSRLFGPRVVNTGWGTPKPDAAHDPDAVIDGEVLDGEVVDVTDDKPRPQQNGPRQLPDSQDPLTTVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q057</accession>
    <name>D3Q057_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase S1 and S6 chymotrypsin/Hap</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5959</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021157.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5959"/>
    <dbReference type="MEROPS" id="S01.121"/>
    <dbReference type="EnsemblBacteria" id="ADD45586">
        <property type="protein sequence ID" value="ADD45586"/>
        <property type="gene ID" value="Snas_5959"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5959"/>
    <dbReference type="eggNOG" id="COG5640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006842_7_5_11"/>
    <dbReference type="OMA" id="EHCSKWN"/>
    <dbReference type="OrthoDB" id="1468733at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049603" evidence="3">
        <location>
            <begin position="31"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="39"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="271" mass="28647" checksum="9605AAFB98BC82A7" modified="2010-04-20" version="1">MKRKTIAVVMAAVAVAAASATALVTGNAFAEDSDPSTKIIGGKPASEDYPFMASLQYEKNGNPDSHRCGTALIDDQWVLTAAHCVVNDDGTVWDPSLLHIKIGSTDNTQGTDVKIEKIVANPDYLAGKENSGDIALLHLAEAPDAPVIKLGGQPEVGSDVREIGWGRTVGDDPNSMPKELQELDTKVLDNEKCVFGDEWDITKGDVCVESPGNQAGACNGDSGSPLLQKVDGEWVTVGVDSRSGGSKCLETDEVYTGVAHYTDWIKSTIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q076</accession>
    <name>D3Q076_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA binding domain protein, excisionase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021176.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5979"/>
    <dbReference type="EnsemblBacteria" id="ADD45605">
        <property type="protein sequence ID" value="ADD45605"/>
        <property type="gene ID" value="Snas_5979"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5979"/>
    <dbReference type="eggNOG" id="COG2452">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_196700_2_0_11"/>
    <dbReference type="OMA" id="LENSGMM"/>
    <dbReference type="OrthoDB" id="2076478at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="11"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="75" mass="8509" checksum="0ABADA102A936B98" modified="2010-04-20" version="1">MTARTHDPEQLLTPAEVASMFRVDPKTVTRWAKAGKLSAIRTLGGHRRYRESEVRDLLHEQIPAPRESVEDLSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0J4</accession>
    <name>D3Q0J4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CapA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2035</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CapA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2035"/>
    <dbReference type="EnsemblBacteria" id="ADD41730">
        <property type="protein sequence ID" value="ADD41730"/>
        <property type="gene ID" value="Snas_2035"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2035"/>
    <dbReference type="eggNOG" id="COG2843">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038823_1_1_11"/>
    <dbReference type="OMA" id="HWGQEYD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07381">
        <property type="entry name" value="MPP_CapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019079">
        <property type="entry name" value="Capsule_synth_CapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09587">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00854">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="PGA_cap" evidence="4">
        <location>
            <begin position="72"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="384" mass="40419" checksum="86F973922A4B9B6C" modified="2010-04-20" version="1">MTGAHSHRDRVPVWRRPVVVAGTALVVLAAVTLTVVWAVSEDKPASAAEDPGSEDTESSAASSPEPDPDAITVTAVGDTIMGNLPDGLPDDGAGYFDKVAEHLKGDIVFGNLDGALSEHDDYKKCKSKKKCFYIRMPPEYASLLKDAGFTVMNGSNNHAFDSGPEGYADTQAALDGAGIDYLGVKGEIVETEVRGVKTAMVGFSTYDRYDSLLDLNLVSQLVSAAAERADVVVVSMHLGAEGVDARHTPEGPETFYGEDRGDSRAATHAAVDAGADLVLGHGPHVLRGMEFYKDRLIAHSLGNFAGYGVLKTSGALGRGAILTVTVDKQGEWVSGKVIPSIMVDGGYPAVDEDNGAHADITELSKDDFPDSGVTLDEKGKISKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Z4</accession>
    <name>D3Q0Z4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease VapC</fullName>
            <shortName evidence="6">RNase VapC</shortName>
            <ecNumber evidence="6">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Toxin VapC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">vapC</name>
        <name evidence="8" type="ordered locus">Snas_4093</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Toxic component of a toxin-antitoxin (TA) system. An RNase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PINc/VapC protein family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019315.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4093"/>
    <dbReference type="EnsemblBacteria" id="ADD43744">
        <property type="protein sequence ID" value="ADD43744"/>
        <property type="gene ID" value="Snas_4093"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4093"/>
    <dbReference type="eggNOG" id="COG1487">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118482_4_0_11"/>
    <dbReference type="OMA" id="SCYPQRA"/>
    <dbReference type="OrthoDB" id="1968541at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00265">
        <property type="entry name" value="VapC_Nob1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022907">
        <property type="entry name" value="VapC_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <keyword evidence="1 6" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="PINc" evidence="7">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="137" mass="15466" checksum="AC08B043EA847EDD" modified="2010-04-20" version="1">MIRYLVDSSALWRILRDGGVRAAWQEAISNGAVGSCQPQRCEFKRSARDRDEFDAMSRMFEDLYPDVAVHKSAWKWMDSVQYRLSAKGKHRGLSVVDLVVAATAAYHGLIVLHDDNDFATVVTEAPDLSERNVNRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q104</accession>
    <name>D3Q104_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4103</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019325.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4103"/>
    <dbReference type="EnsemblBacteria" id="ADD43754">
        <property type="protein sequence ID" value="ADD43754"/>
        <property type="gene ID" value="Snas_4103"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4103"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_3_0_11"/>
    <dbReference type="OMA" id="TLCATPQ"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="28"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="117"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="183" mass="20274" checksum="F92CCDAB8EA9EABB" modified="2010-04-20" version="1">MADSNWPGENLVTAARDGDVASITALVSGSHPHVRRFAHSLCATPEDAEDAAQEALIVLYRKIGTLRASKALASWMFRIVRNECLRRARQLLHRREPIPDDVTTSAEAEVVRRLEAERVAEAVAALPIDQRRVLIMRDIQGYSGRMVATTLGLSTAAMKSRLHRARTTVRESLQYPMTGADDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q108</accession>
    <name>D3Q108_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019329.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4107"/>
    <dbReference type="EnsemblBacteria" id="ADD43758">
        <property type="protein sequence ID" value="ADD43758"/>
        <property type="gene ID" value="Snas_4107"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4107"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_4_3_11"/>
    <dbReference type="OMA" id="YPQDAQV"/>
    <dbReference type="OrthoDB" id="912110at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="5"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="393" mass="40399" checksum="0FC15B07D42A1373" modified="2010-04-20" version="1">MGSVDVVIVGAGVIGAACAEALSAAGQRVLVLDRGSPTGGTTAAGEGNVLVSDKEPGPELELAQESRRYWPLLLASLREELGAKLAEAEWDAKGGLVVALGETDATALAGFAETQRAAGVDARVISVDEVREREPHLTDGIRAAVYYPEDAQLQPVLAASALLSAVRARGGAVRGGVAVTGVGTDASGAVSSVNTSDGAISCRAVVNACGPWAGEFARAAGAPIAVLPRRGMVLVTAPLPDVVRHKVYDADYVGATVSGDADLQTSTVVESTRAGTVLIGSSRQRVGFDETIRVEVLRELARKAVGLFPVLGNVPVMRAYGGFRPYTPDHLPVIGADPRLPGLWHATGHEGAGIGLAAATGRLLADQFLGRESVLDPEPFRVDRPALLEGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q148</accession>
    <name>D3Q148_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycerate kinase</fullName>
            <ecNumber evidence="5">2.7.1.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4147</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycerate kinase type-1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.31" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019369.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4147"/>
    <dbReference type="EnsemblBacteria" id="ADD43798">
        <property type="protein sequence ID" value="ADD43798"/>
        <property type="gene ID" value="Snas_4147"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4147"/>
    <dbReference type="eggNOG" id="COG1929">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028255_0_0_11"/>
    <dbReference type="OMA" id="CRFEVAC"/>
    <dbReference type="OrthoDB" id="1292731at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008887">
        <property type="term" value="F:glycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031388">
        <property type="term" value="P:organic acid phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018193">
        <property type="entry name" value="Glyc_kinase_flavodox-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004381">
        <property type="entry name" value="Glycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018197">
        <property type="entry name" value="Glycerate_kinase_RE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036129">
        <property type="entry name" value="Glycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21599">
        <property type="entry name" value="PTHR21599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02595">
        <property type="entry name" value="Gly_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006078">
        <property type="entry name" value="GlxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110738">
        <property type="entry name" value="SSF110738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00045">
        <property type="entry name" value="TIGR00045"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR006078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="372" mass="37495" checksum="599ED113103BEEEF" modified="2010-04-20" version="1">MRVLICPDKFAGTLSAPEAAAAVAEGWHEVNPDDQLDVLPLSDGGPGMLDALAAALDGRRESFDIVDPLGRKVSGDILLVGDTAYIESAEACGLHLLDPEERDPLRATSFGLGQLMTAAVEAGARTLVIGLGGSATNDAGAGMLTALGLTPLDSLNRALPYGGGVLADCVTLDGAARLRGATIVAATDVDNPLCGINGASAIFGPQKGASDNDVQILDHALSTFGHVLSGIPGSPPNVADLPGAGAAGGLGAALFALGGSRASGADLIGRAVGLREALDSCDLVITGEGSFDHQSLRGKLVSGIAEAATERGLPCVVVAGRVTVGRREALTAGITRTMSLTEHFGSSEEAMAKPAEGLTALGAKLAQKWRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q175</accession>
    <name>D3Q175_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_6030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
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        <property type="protein sequence ID" value="ADD45655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021226.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6030"/>
    <dbReference type="EnsemblBacteria" id="ADD45655">
        <property type="protein sequence ID" value="ADD45655"/>
        <property type="gene ID" value="Snas_6030"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6030"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_2_11"/>
    <dbReference type="OMA" id="NMATWML"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="14"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="128"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="235"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="391" mass="41908" checksum="DCF532C2A636DA79" modified="2010-04-20" version="1">MAANPQFDAYRLPEEHEAIRAATREVCDAEVAPRAAEADANAEFPQKSYDALRSADLHAPHIPEEYGGAGIDALGTAIVIEEVARACASSSLIPAVNKLGTMPLLLAASDELKRKFLPPVASGEAMFSYCLSEPEAGSDVAGMKTKAEKDGDAFVLNGAKRWITNAGVSRYYTVFAVTDPGKGAHGISAFVVDSEDEGVSFGAPEHKLGIKGSPTREVYFDNVRVGADRLVGAENEGFKIAMRTLDHTRVTIAAQAVGIGQGALDYAAGYVKERQQFGRAVADFQGVQFMVADAAMKLSAARQLTYTAAAKSEREDDDLTFYGASAKCFASDVAMEVTTDAVQLLGGYGYTSDYPVERMMRDAKITQIYEGTNQVQRVVMAKQFLKGLVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1E8</accession>
    <name>D3Q1E8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YhgE/Pip N-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021299.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45728">
        <property type="protein sequence ID" value="ADD45728"/>
        <property type="gene ID" value="Snas_6104"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6104"/>
    <dbReference type="eggNOG" id="COG1511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004534_1_1_11"/>
    <dbReference type="OMA" id="MQIGIGK"/>
    <dbReference type="OrthoDB" id="1240965at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017501">
        <property type="entry name" value="Phage_infect_YhgE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017500">
        <property type="entry name" value="Phage_infect_YhgE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023908">
        <property type="entry name" value="xxxLxxG_rpt"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03062">
        <property type="entry name" value="pip_yhgE_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03061">
        <property type="entry name" value="pip_yhgE_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03057">
        <property type="entry name" value="xxxLxxG_by_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="434"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="471"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="496"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="562"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="597" mass="63046" checksum="4D57C9B7E30707A0" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1H0</accession>
    <name>D3Q1H0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">L-asparaginase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021321.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6126"/>
    <dbReference type="EnsemblBacteria" id="ADD45750">
        <property type="protein sequence ID" value="ADD45750"/>
        <property type="gene ID" value="Snas_6126"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6126"/>
    <dbReference type="eggNOG" id="COG4448">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062004_0_0_11"/>
    <dbReference type="OMA" id="DDCGAPT"/>
    <dbReference type="OrthoDB" id="1434447at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010349">
        <property type="entry name" value="Asparaginase_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42110">
        <property type="entry name" value="PTHR42110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06089">
        <property type="entry name" value="Asparaginase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="33728" checksum="A29EB4D2EBEDEC77" modified="2010-04-20" version="1">MTKAYRGGGLLAEIVRSGFVEGFHRGSAVVLDANGGVRDSIGDIDAPIFPRSANKPMQTLGALRSGLPFTAPADLALASASHRGEPFHVDAVRSLLERAELSPEALQCPPAWPIEESARDAAIASGAGKSRLTMNCSGKHAAMLATSRAAGWSTDDYLSPNHPLQQANARATTDLTGYDIAAIGVDGCGAPLVAYPLLGLARAFLHLVHAEPGTPERAVADGMRAHPELVSGTHGFDTRLMRAVPTALAKLGAEGVQALAVPGVGAVAVKIDDGDNRASGPVAVSALRTMDLTNLSLDKSTLDKLATTPLYGGGKRVGSVRPVWPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q261</accession>
    <name>D3Q261_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2238</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017499.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2238"/>
    <dbReference type="EnsemblBacteria" id="ADD41928">
        <property type="protein sequence ID" value="ADD41928"/>
        <property type="gene ID" value="Snas_2238"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2238"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_3_0_11"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="21929" checksum="3649464A530A0207" modified="2010-04-20" version="1">MSWHVILTFVLGLLPITLTPGTTATLVVQYVSLGGRRHGAAVLAGSITGLFAHATFATLGLSALIMASATAFTIVKYAGAAYLVGLGVYLMFTGARRHDDPQQSRIVPSVPKVYRHALIANILNPRAALIVLTLPAQVVTPDFTITQAAYTLVVVDAVMIVLWLGLWTQAIASAKRFGLFKKLAQQFSRFGGLLLIALGIRTAVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q298</accession>
    <name>D3Q298_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019402.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4181"/>
    <dbReference type="EnsemblBacteria" id="ADD43831">
        <property type="protein sequence ID" value="ADD43831"/>
        <property type="gene ID" value="Snas_4181"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4181"/>
    <dbReference type="HOGENOM" id="CLU_1926281_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="131" mass="14288" checksum="5926693045284A59" modified="2010-04-20" version="1">MTTDRPDNNPASIINNHGTVHTASQTGPGYVGAMGENATGYLYLDGKATADTELRQLVTELRDLLQTHAADLSNPDEVADAIDDLEDKVGDNAAPEKLKRTTRIILRLTQPIQAFVDLIGRIHDLIEKLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2H4</accession>
    <name>D3Q2H4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage shock protein A, PspA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4258</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PspA/IM30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019478.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4258"/>
    <dbReference type="EnsemblBacteria" id="ADD43907">
        <property type="protein sequence ID" value="ADD43907"/>
        <property type="gene ID" value="Snas_4258"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4258"/>
    <dbReference type="eggNOG" id="COG1842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048860_0_0_11"/>
    <dbReference type="OMA" id="QNAMVLQ"/>
    <dbReference type="OrthoDB" id="1674247at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007157">
        <property type="entry name" value="PspA_IM30"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04012">
        <property type="entry name" value="PspA_IM30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="238"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="27"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="127"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="260"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="284" mass="30917" checksum="4ECD827AD2F34D37" modified="2010-04-20" version="1">MANPFAKGWNYMMALFGAKIDEHADPKIQIQQAVEEAQRQHQALTRQAAAVIGNQRQLEMKLSRTMSEVEKLQSQARQALVLADKARAEGDEKKATEYENTAQVLAGQLVSSEQSMEDMKSMHDQAISAAEQARQAVENNQMILQQKLAERSKLLSQLEQAKMQETIASSLESMSSLAAPGNVPSLDEVRDKIEKRYATAMGRADLAGNSVEGRMMEIQKATVDMAGASRLEQIRASLQGDKIGGSDKTAIGGAEAEEKPASVSRLDEIRASLSNDKNRDAAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2I8</accession>
    <name>D3Q2I8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribonuclease J</fullName>
            <shortName evidence="9">RNase J</shortName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rnj</name>
        <name evidence="12" type="ordered locus">Snas_4272</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer, may be a subunit of the RNA degradosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019492.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4272"/>
    <dbReference type="EnsemblBacteria" id="ADD43921">
        <property type="protein sequence ID" value="ADD43921"/>
        <property type="gene ID" value="Snas_4272"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4272"/>
    <dbReference type="eggNOG" id="COG0595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008727_3_1_11"/>
    <dbReference type="OMA" id="KNTCVFE"/>
    <dbReference type="OrthoDB" id="580619at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01491">
        <property type="entry name" value="RNase_J_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004613">
        <property type="entry name" value="RNase_J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042173">
        <property type="entry name" value="RNase_J_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030854">
        <property type="entry name" value="RNase_J_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041636">
        <property type="entry name" value="RNase_J_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17770">
        <property type="entry name" value="RNase_J_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004803">
        <property type="entry name" value="RnjA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00649">
        <property type="entry name" value="MG423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="11">
        <location>
            <begin position="31"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9 10">
        <location>
            <begin position="374"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR004803-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD43921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="568" mass="60559" checksum="8551588613642784" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2S7</accession>
    <name>D3Q2S7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021399.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6206"/>
    <dbReference type="EnsemblBacteria" id="ADD45828">
        <property type="protein sequence ID" value="ADD45828"/>
        <property type="gene ID" value="Snas_6206"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6206"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_0_3_11"/>
    <dbReference type="OMA" id="MTLHYPE"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="321" mass="35435" checksum="A1F1EA2C720DEDE1" modified="2010-04-20" version="1">MTSLPETPSNVLVVRDGKVVHQESHGLADPVAGTPLTPDHRFQIASISKQFTAAATLLLADAGKLSVDDPLSKWVSGSPESWKPLTLHHLLSNSSGIGHWNDYPEIDLGEPMPIDDLIATFQQRELFCEPGSQFRYSSAGFCLLAHIVELVSDTPYREFLDQRIFTPLGMTDTFAGNAGDRPNIAVGCAPDGTPREKLFELDLVGRGAGDIWSTTTDMVTWNQAVADGRILSDESRRRSFTPHVFCDSVFDEEHHYGYGWFVGTIKHPVRYHTGGNAGFESFSGWFPELSAHVVFLTNRDGYFSEIGNEGQRELILEHLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2T9</accession>
    <name>D3Q2T9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAD-superfamily subfamily IB hydrolase, TIGR01490</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6219</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily. SerB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021411.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6219"/>
    <dbReference type="EnsemblBacteria" id="ADD45840">
        <property type="protein sequence ID" value="ADD45840"/>
        <property type="gene ID" value="Snas_6219"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6219"/>
    <dbReference type="eggNOG" id="COG0560">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052657_0_1_11"/>
    <dbReference type="OMA" id="FGRGLYK"/>
    <dbReference type="OrthoDB" id="1472357at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006385">
        <property type="entry name" value="HAD_hydro_SerB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01490">
        <property type="entry name" value="HAD-SF-IB-hyp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="289" mass="31351" checksum="1B897B8FA96ECB9F" modified="2010-04-20" version="1">MNDDRSAVEAATVVTDTSHIDERAAAFFDVDNTLVHGASIYWFARGLAARRYFRHRDLLQFVWQQARFRIRGKELGGGSINEIKESALSFVAGRRVADFVALGEEIFDDTIEAKIWSGTQALADAHLAAGQQVWLVTATPVELAEIIARRLGFTGAIGTVGEVHDGVYTGRLVSDIMHGPAKAEAIRELAKREDLDLDLCTAYSDSSNDMPMLKAVGHAVAINPDAALRRQARHHGWQVRDFRTGRKAAKFAVPAVVAGAVVGAIAGGAAWKRRGAARRAMSPNGRPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2W7</accession>
    <name>D3Q2W7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6248</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021439.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6248"/>
    <dbReference type="EnsemblBacteria" id="ADD45868">
        <property type="protein sequence ID" value="ADD45868"/>
        <property type="gene ID" value="Snas_6248"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6248"/>
    <dbReference type="HOGENOM" id="CLU_1642700_0_0_11"/>
    <dbReference type="OrthoDB" id="2076478at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="161" mass="17416" checksum="848E662523768ABD" modified="2010-04-20" version="1">MNASFQAVTGAPDVRPRFFEIPEIVEQLPLSKDGVYREIHAGNLAAIRIGGAHGGKYIVPARLLDLMDAQMRGVGFDTTVSELSGRFLSIAEAASILRISRPVLAKRARGHEFPAARYGGKHIIAGAVIDDMETKALHAMTLIRTDDYVACVRQTAMEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Y0</accession>
    <name>D3Q2Y0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="7">SHMT</shortName>
            <shortName evidence="7">Serine methylase</shortName>
            <ecNumber evidence="7">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glyA</name>
        <name evidence="10" type="ordered locus">Snas_0231</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0231"/>
    <dbReference type="EnsemblBacteria" id="ADD39950">
        <property type="protein sequence ID" value="ADD39950"/>
        <property type="gene ID" value="Snas_0231"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0231"/>
    <dbReference type="eggNOG" id="COG0112">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022477_2_1_11"/>
    <dbReference type="OMA" id="GRRYYEG"/>
    <dbReference type="OrthoDB" id="861782at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="9">
        <location>
            <begin position="12"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="128"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD39950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="423" mass="45171" checksum="3B1C094722797B66" modified="2010-04-20" version="1">MSDSKNLMRRLVEADSEVAQLIDAEGRRQHDKIRLIASENYVSQAVMEATGTLLTNKYSEGYAGKRYYEGQQLIDEVEELAISRAKSLFGVDHANVQPYSGSPANLAVYLAFAQPGDTVMGMSLPMGGHLTHGWSVSATGKWFNAVHYGVRKDTGRVDFDEVAELARQHRPKLIFCGGTAIPRTVDFAAFAKIAQEVDAILVADIAHIAGLVAGGAHPSPVGHAEVVTTTTHKTLRGPRGAMLMSTEERAKALDKAVFPGLQGGPHNHTTAAIAVALREAATPDFADYATRIVANAKALAAALTERGFDLVSGGTDNHLILADLTSKDIGGKPAAKALDRAGVELNFNTVPFDPRKPFDPSGLRIGTAAVTTRGMTEADMPKIAAWMDDAISAAHDGQEDKLDDIAGQIRDFCAAYPIPGWTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Z7</accession>
    <name>D3Q2Z7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015538.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0249"/>
    <dbReference type="EnsemblBacteria" id="ADD39967">
        <property type="protein sequence ID" value="ADD39967"/>
        <property type="gene ID" value="Snas_0249"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0249"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071582_0_0_11"/>
    <dbReference type="OMA" id="NWQMPVM"/>
    <dbReference type="OrthoDB" id="1389691at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="130"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="254" mass="27169" checksum="FB4F92E024B17626" modified="2010-04-20" version="1">MTVDVNSVDQPASLAEAPLRQARNSGAFWAATARSRGHEVLRRPGFVAAVGDERAGTRVLIQEPGLDGDAVAEIVELARGAAGPVDVEDPFSATDLSQLGYRNWQMPVMLRQPGPVEEPHLEVVRAGNAAELRAAERAVIDGFELVRFEPYRGNEMFPEALLDEDGVDVFIVRVDGGEVAGACVTVVDNGYGSHYWVGTPEAFRSRGVGRAAMLGSLAPLADMPVTLTASRLGRPLYESLGFAVAAPATWWASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q311</accession>
    <name>D3Q311_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015552.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0263"/>
    <dbReference type="EnsemblBacteria" id="ADD39981">
        <property type="protein sequence ID" value="ADD39981"/>
        <property type="gene ID" value="Snas_0263"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0263"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_457723_0_0_11"/>
    <dbReference type="OMA" id="DTGPMGV"/>
    <dbReference type="OrthoDB" id="1560944at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028208">
        <property type="entry name" value="Effector_pro_NleD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14891">
        <property type="entry name" value="Peptidase_M91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="684"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="742" mass="78998" checksum="CD84BFEEB0BE8DDB" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q337</accession>
    <name>D3Q337_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative phenylalanine aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pat</name>
        <name evidence="5" type="ordered locus">Snas_0289</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May catalyze the transamination reaction in phenylalanine biosynthesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015578.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0289"/>
    <dbReference type="EnsemblBacteria" id="ADD40007">
        <property type="protein sequence ID" value="ADD40007"/>
        <property type="gene ID" value="Snas_0289"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0289"/>
    <dbReference type="eggNOG" id="COG0079">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_3_3_11"/>
    <dbReference type="OMA" id="NYHVAGF"/>
    <dbReference type="OrthoDB" id="1248286at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01513">
        <property type="entry name" value="Phe_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024892">
        <property type="entry name" value="Pat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="33"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="360" mass="38418" checksum="DEF1D62664EC75E5" modified="2010-04-20" version="1">MSRPLTRADLDALPSYVPGRNPADLARELGLTEAIKLASNEVPFGLLPGVAEAVAEAAAQGHRYPDMGVLALREALAERFKVDVDRVATGCGSVALFEHVVKAAATRGDEVLYSWRSFEAYPIVVAGVGATSVRVPNTPGHGHDLEAMAAAITPKTRIVVVCNPNNPTGTSVGRAAMDAFVDAVPSDVLIVVDEAYREFVTDPDVPDALEEYGDRPNVVVLRTFSKAWGLAGLRAGYLVAAPEVADAVRKVVTPFSTNACVQAAALAALEADVEMRRRAAIMISERDRLTTALRALVPQIPDSQSNFLWLPIGEQTVPFAKHCESRGVIVRPFAGEGVRASFGTPEQNDRFVAVASEFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q391</accession>
    <name>D3Q391_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0343</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015632.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0343"/>
    <dbReference type="EnsemblBacteria" id="ADD40061">
        <property type="protein sequence ID" value="ADD40061"/>
        <property type="gene ID" value="Snas_0343"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0343"/>
    <dbReference type="HOGENOM" id="CLU_2939554_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="60" mass="6581" checksum="D456B5A20CCBAF12" modified="2010-04-20" version="1">MATTKLQLGDVVVHIPTGLKGKVKELDGDDVLVKWNGGTLVSPEGENWLDAADLRFYGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q398</accession>
    <name>D3Q398_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_17 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015639.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0350"/>
    <dbReference type="EnsemblBacteria" id="ADD40068">
        <property type="protein sequence ID" value="ADD40068"/>
        <property type="gene ID" value="Snas_0350"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0350"/>
    <dbReference type="eggNOG" id="COG3311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140176_13_0_11"/>
    <dbReference type="OMA" id="RTVDEKM"/>
    <dbReference type="OrthoDB" id="2076478at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="8"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="67" mass="7725" checksum="2D7169EF4A057C42" modified="2010-04-20" version="1">MTTTTKEWLTVPEFLDEFDIARSTFQDWRAKGTAPPCRKLPNGQLRLKRSEVNEWLESLVDNSEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3E2</accession>
    <name>D3Q3E2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ADP-ribosylation/Crystallin J1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2294</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017554.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2294"/>
    <dbReference type="EnsemblBacteria" id="ADD41983">
        <property type="protein sequence ID" value="ADD41983"/>
        <property type="gene ID" value="Snas_2294"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2294"/>
    <dbReference type="eggNOG" id="COG1397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060257_0_0_11"/>
    <dbReference type="OMA" id="HQSSYGR"/>
    <dbReference type="OrthoDB" id="1661477at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005502">
        <property type="entry name" value="Ribosyl_crysJ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036705">
        <property type="entry name" value="Ribosyl_crysJ1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03747">
        <property type="entry name" value="ADP_ribosyl_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101478">
        <property type="entry name" value="SSF101478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="383" mass="40231" checksum="F50F4858320A642B" modified="2010-04-20" version="1">MDTLVDKATGALTGSAVGDALGGAAEGNPPEAIQERYGGFIEGIVPPFLADWRNARPIAPYHKGDGHITDDTLMTSALVDVYDTVRDHLDAHAIAEHLVPLLIGDKRWIPELETEALLLHRVFLAEKWLVARLHYGHIDPREAGVGNIVNCGATMYVAPIGIVNAGSPEAAYAEAIDVAGAHQSSYGREAAGVFAAAVAEAMRPGATVETVIDRALSLAKDGTKSAIDAVAQAASGVDDWRTGLAELRRAVEPFDTVGPHYRQPAMDARIPSRTKSIEELPIALGMLIAADGDYREAVLGAVNYGRDSDSIAVMAGSLAGALHGIDAVPREWIDGVSEGSRMDITATGPVIAAVARDVWAADAQRAEQAAKTRAALTATEAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3G5</accession>
    <name>D3Q3G5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017577.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42006">
        <property type="protein sequence ID" value="ADD42006"/>
        <property type="gene ID" value="Snas_2319"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2319"/>
    <dbReference type="eggNOG" id="ENOG5032VWP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1694563_0_0_11"/>
    <dbReference type="OMA" id="PHKAIRR"/>
    <dbReference type="OrthoDB" id="1766089at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="167" mass="18959" checksum="8C26553AF0078E81" modified="2010-04-20" version="1">MTRHLTFDPAAPVSRPDVDDSPVTGLVPDSVRYVLERAETWLGWDGTAVLSDGNAWTPHKALRRVGDHLIDHLAEIECRLAGMPTIPDRWHGRKLTLDGDWARFTEADLDEATSRLGRLAVWYEARMSALDDNTLDHRPDPDTWTIREVVHHVANVRYYADQLDEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3H1</accession>
    <name>D3Q3H1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protocatechuate 3,4-dioxygenase, alpha subunit</fullName>
            <ecNumber evidence="5">1.13.11.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2325</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.3" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017583.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2325"/>
    <dbReference type="EnsemblBacteria" id="ADD42012">
        <property type="protein sequence ID" value="ADD42012"/>
        <property type="gene ID" value="Snas_2325"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2325"/>
    <dbReference type="eggNOG" id="COG3485">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027719_7_1_11"/>
    <dbReference type="OMA" id="YRFDIHL"/>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018578">
        <property type="term" value="F:protocatechuate 3,4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019439">
        <property type="term" value="P:aromatic compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012786">
        <property type="entry name" value="Protocat_dOase_a"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="SSF49482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02423">
        <property type="entry name" value="protocat_alph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INTRADIOL_DIOXYGENAS" evidence="4">
        <location>
            <begin position="32"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="182" mass="19690" checksum="DD1CB251B8D6EE99" modified="2010-04-20" version="1">MTTPSQTVGPFFGFALPWPDGPYAAPPDTPGLITVRGVVLDGAGAPVPDALIETWQADPDGRFDHPDDPRGCQTSAARWFARCPTDDNGRYAVHTVKPGPVSDGEERHAPHLNVTVLARGLLRHLVTRMYFPDESEANGTDPVLCGLPEPERAVTLIAVPDGDGLRFDIRLRGDHETVFFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3I2</accession>
    <name>D3Q3I2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2337</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017594.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2337"/>
    <dbReference type="EnsemblBacteria" id="ADD42023">
        <property type="protein sequence ID" value="ADD42023"/>
        <property type="gene ID" value="Snas_2337"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2337"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_3_0_11"/>
    <dbReference type="OMA" id="DYPHLGQ"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003012">
        <property type="entry name" value="Tet_transcr_reg_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00400">
        <property type="entry name" value="TETREPRESSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="6">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="23164" checksum="83FA8F09AF109EBA" modified="2010-04-20" version="1">MARPRRPLLSRDRITAAALAVVDADGLEALSTRRLATELGVSGPSLYNHVATKDELLDDVVDSVLGEVDTTAMAGLSPSRRDWATALAAWARSYRTALAAHPNIVPALASGPGNRPHALRIADAVFGGLVGAGWPRREATRVGALMRYFVTGSALGSFAGGFPADAAVYESGYPHLDQAHLLAERQQRIDDEAFETGLAALLEGLGARYRRLTDAPHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3L5</accession>
    <name>D3Q3L5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017627.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2371"/>
    <dbReference type="EnsemblBacteria" id="ADD42056">
        <property type="protein sequence ID" value="ADD42056"/>
        <property type="gene ID" value="Snas_2371"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2371"/>
    <dbReference type="HOGENOM" id="CLU_1234391_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048213" evidence="2">
        <location>
            <begin position="23"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="224" mass="24266" checksum="8E3E3E78B0DE3BF7" modified="2010-04-20" version="1">MRKTIAIGVAAVLSFALVACSANTEKPKAESTSSESTAKDEGKDWAKEAEKSLVSTDMESLSEHKAEFDKPKSVDDARPFPECEMNESVHGDVRGGVHQRFKGDPDISAYAYAVDGSAADQFEKLVKAFGEKECQEFETKTDEGTFEYKLLDDADTTEDLRKELLFGACFEVTDTKSGDKSGECRMIYVVGENGIAELTSKQDVELNGVSTLMLGLVAAEAMSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q466</accession>
    <name>D3Q466_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_6333</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021522.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6333"/>
    <dbReference type="EnsemblBacteria" id="ADD45951">
        <property type="protein sequence ID" value="ADD45951"/>
        <property type="gene ID" value="Snas_6333"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6333"/>
    <dbReference type="eggNOG" id="COG0303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010186_1_2_11"/>
    <dbReference type="OMA" id="KMPKVAF"/>
    <dbReference type="OrthoDB" id="651103at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="9">
        <location>
            <begin position="170"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD45951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="395" mass="40564" checksum="5A97095024276B9B" modified="2010-04-20" version="1">MATLDWDSARNEVHLAASEAKLIPLRQKPSETDGATLAAPLTALTPLPAFDTSSVDGYAVRGPGPWRLTGRILAGQTASEIETGCAIEVATGAMVPRGLDAIVRLEDATVTGDKVTGTPRDKPEWRRVGEESELDEELLPAGTPVTPAVIGMAATAGYDTIEVRPKPRAAVLVFGDELASEGKPGNGRVRDALGPMMPNLLRRAGAAPVPGFCPRGPIEDNLDSHIAVLRAALDDADIVCTTGGTMHGPVDHLHPALTALGAKYVVNTVAVRPGFPMLVASLPGQRFVAGLPGNPQSAVVALASLVVPLIAGLSGRVLPPLPRVQLAADIPGRGPDTHLALVRQDATGLAHPLPHTGSSMLRGLASAVGFAVVEPGESGKAGQSVRLLPLPGGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4A4</accession>
    <name>D3Q4A4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6373</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021560.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6373"/>
    <dbReference type="EnsemblBacteria" id="ADD45989">
        <property type="protein sequence ID" value="ADD45989"/>
        <property type="gene ID" value="Snas_6373"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6373"/>
    <dbReference type="eggNOG" id="ENOG5033IX6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152505_0_0_11"/>
    <dbReference type="OMA" id="MSWDVLL"/>
    <dbReference type="OrthoDB" id="1801284at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="133" mass="14278" checksum="DF1260590F9D7C0B" modified="2010-04-20" version="1">MSWDVLLLRIPEGVTAIDQIPDDIPATPLGSRDDILAAISRVAPEANLSDPTWGQLNGEDWSMEFNIGSDDPVDSVMLHIRGGGDDMENVMFGVAGALNCQVIDCSGGDVLTPENGSSGWRAFQEYRDQVIGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4E5</accession>
    <name>D3Q4E5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular small neutral protease</fullName>
            <ecNumber evidence="3">3.4.24.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Snapalysin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0388</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes proteins with a preference for Tyr or Phe in the P1' position. Has no action on amino-acid p-nitroanilides.</text>
            <dbReference type="EC" id="3.4.24.77"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M7 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.77" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015676.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0388"/>
    <dbReference type="EnsemblBacteria" id="ADD40105">
        <property type="protein sequence ID" value="ADD40105"/>
        <property type="gene ID" value="Snas_0388"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0388"/>
    <dbReference type="eggNOG" id="COG5640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124996_0_0_11"/>
    <dbReference type="OMA" id="AAIWNDS"/>
    <dbReference type="OrthoDB" id="1649119at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000013">
        <property type="entry name" value="Peptidase_M7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02031">
        <property type="entry name" value="Peptidase_M7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00787">
        <property type="entry name" value="NEUTRALPTASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048656" description="Extracellular small neutral protease" evidence="6">
        <location>
            <begin position="33"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="194" mass="20496" checksum="95C6D09A92500C41" modified="2010-04-20" version="1">MTERSRLLRRGVLAAFGVGALLAIASPALATAQPVADTASETKAVTLTYDTSQAEEFVQDVHDGAKVWNDNVENVTLEPVADGQTADFEVIATDGWPQASVPELGKGTIEFGRQAVDEGHNTTRISAHEIGHILGLPDVKPGPCSSLMSGASAGTDCDNAIPNAEEKAEVESNFGSGMAAKSKTWRDMYFCDKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Q6</accession>
    <name>D3Q4Q6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017657.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2403"/>
    <dbReference type="EnsemblBacteria" id="ADD42086">
        <property type="protein sequence ID" value="ADD42086"/>
        <property type="gene ID" value="Snas_2403"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2403"/>
    <dbReference type="eggNOG" id="ENOG502ZKIK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2556653_0_0_11"/>
    <dbReference type="OMA" id="GVSDYTQ"/>
    <dbReference type="OrthoDB" id="2074305at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="SSF103647"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="82" mass="8798" checksum="C48305EBA7B7B5B8" modified="2010-04-20" version="1">MNDKKTFEMDINGDGKPDTVQVEKNADGSTTYLVDTDGDGKTDLHAIDHDSDGVIDEVRIDRDGDGVADDRLADDTGDGKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q559</accession>
    <name>D3Q559_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4463</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019679.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4463"/>
    <dbReference type="MEROPS" id="U72.001"/>
    <dbReference type="EnsemblBacteria" id="ADD44108">
        <property type="protein sequence ID" value="ADD44108"/>
        <property type="gene ID" value="Snas_4463"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4463"/>
    <dbReference type="eggNOG" id="COG4122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040524_1_0_11"/>
    <dbReference type="OMA" id="YFRGRCL"/>
    <dbReference type="OrthoDB" id="537546at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019941">
        <property type="term" value="P:modification-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022366">
        <property type="entry name" value="Pup_deamidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004347">
        <property type="entry name" value="Pup_ligase/deamidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42307">
        <property type="entry name" value="PTHR42307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03136">
        <property type="entry name" value="Pup_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018077">
        <property type="entry name" value="UCP018077"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03688">
        <property type="entry name" value="pupylate_PafA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR018077-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="506" mass="56139" checksum="831050139EDB1D1B" modified="2010-04-20" version="1">MTVRRIMGTEVEYGISVPGQPGANPMVSSSQIVNAYGARPELTKGGRARWDYEEESPLRDARGFTYTGALYDPAETLADEDTGLANVILTNGARLYVDHAHPEYSTPEVTNPRDIVLWDKAGEVIMAEAAKRAASVPGSPYINLYKNNTDNKGASYGAHENYLMARSTPFADIVTHFTPFLVTRPVVCGAGRVGIGQDGSKDGFQISQRADYFEVEVGLETTLKRPIINTRDEPHADADQYRRLHVIIGDANLSEISTYLKVGTAALILSMIEDEAMDPGLSIAEPVNELKAISHDPTLAHKVRLRDGRKMTAVQIQQEFHDRATAYVERKYGADADEDTKDVLRLWGETLDKLARDPMECARELDWVAKLRLLNGYRDRERLDWGASKLELIDLQYSDVRPGKGLYHRLVAKGAMRTLFTDEQVREAMTNPPTDTRAYFRGRCLAKYPSEVVAASWDSLIFDVGRESLVRVPMMEPGKGTAEHVGALFDRCPSAKDLLDIITGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5L9</accession>
    <name>D3Q5L9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-binding region ATPase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6464"/>
    <dbReference type="EnsemblBacteria" id="ADD46079">
        <property type="protein sequence ID" value="ADD46079"/>
        <property type="gene ID" value="Snas_6464"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6464"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090336_5_1_11"/>
    <dbReference type="OMA" id="ACKHGRP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="19"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD46079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="164" mass="17443" checksum="3379449F1688ABA8" modified="2010-04-20" version="1">MHTMVNTPASWQARVPHHARSAAAVRRWLAGLAGDLHSQHLADLHAVATELICNAVRHATPLPDGDLSVHFQMNGGTIEFAVTDGGASTRPFVRALNTSASDGRGLLIVTALAEQWGVRDESGGRTVWARLTGTDVPPLDEVDTEPLGAPANNRAKTDTTKLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5Z7</accession>
    <name>D3Q5Z7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type Na+ efflux pump permease component-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015867.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0582"/>
    <dbReference type="EnsemblBacteria" id="ADD40296">
        <property type="protein sequence ID" value="ADD40296"/>
        <property type="gene ID" value="Snas_0582"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0582"/>
    <dbReference type="eggNOG" id="COG1668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046841_3_1_11"/>
    <dbReference type="OMA" id="FGYLIMM"/>
    <dbReference type="OrthoDB" id="1155696at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="387" mass="40899" checksum="ADA9B79519048309" modified="2010-04-20" version="1">MKGLWLVARREILVRGKSKSYLIGLLASAVLVVVVSLLPTFLGGDDTYKIAVTGTDAPVLAESVPEVGEAHGMKIEADEVDDAAAAKAAISDDKADIAIVDNKTVIADGEPDQGLLTVVEAVHQRVIAERQLVDAGADPDKVSDAMKVDTLKTEQVNGEDNTARQVIGYFLTIILFFMVMMPTMYVAMGVVEEKSSRIVEILLSSLRTWQLLGGKILGLGVLGFLNLAVPAGVGLIAATATGAIDYLPSGMGVTIVTALGWWVLGFAFYAAMAGSLGSLVSRQEDINSAIGPMTMLMVASYVVTSIYVWDPTATVSKVLSFIPPFSMLMMPVRAAVNDAAPWEQLLSAAVLAAAAVGMLSIGATIYKRSVMRIGSKVKLTEIFTKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q601</accession>
    <name>D3Q601_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NLP/P60 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0586</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0586"/>
    <dbReference type="MEROPS" id="C40.007"/>
    <dbReference type="EnsemblBacteria" id="ADD40300">
        <property type="protein sequence ID" value="ADD40300"/>
        <property type="gene ID" value="Snas_0586"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0586"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_634469_0_0_11"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048894" evidence="4">
        <location>
            <begin position="29"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="5">
        <location>
            <begin position="245"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="29"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="372"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="178"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="432" mass="46542" checksum="1DF5E9BE5BD32044" modified="2010-04-20" version="1">MKTTPSRVVMCLGTAVLLGISTPVPALADPVTVVPDDGSRPEGGAPAGDQEPGEVPISGPGISRGPYADKIAEQTRSLADLGERTTDAEEQLKLRKDETSLSRLNWRDLDGEAKATEELAADMAAAAYQEKAAEIPGLTDKFEDLFEVNPELLNLNQNAIMEEAEDARSDAGVAKATLDAAEATEAIAEGEHKDLSKKLDKKTKSLEKLIERNREAITLEEQQAEANNERETGQISIDIDGAEAAEEAKQAVKFALKQTGKSYVWGDEGPNTYDCSGLTQTSYGQPGVRLPRIAKQQFRDTSQARVPMEKLLPGDLIFYGDVPEDWTSVYHVGMYIGDGQMVHAPRPGDVVRVAPVWFDEFVGAHRVVQAVDTKPAESKEKKDKKEKKRADSPSETPATKPESPPVPGSDEETTSGPGGGDAPTPTPTPWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q626</accession>
    <name>D3Q626_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2519"/>
    <dbReference type="EnsemblBacteria" id="ADD42201">
        <property type="protein sequence ID" value="ADD42201"/>
        <property type="gene ID" value="Snas_2519"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2519"/>
    <dbReference type="eggNOG" id="COG0718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1569737_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="170" mass="18161" checksum="38976B1C6A8F799B" modified="2010-04-20" version="1">MLKTALANLVRRLSESGARLDPDDPRFDSRLAREALAVRAVDVPTVDGLVWVSMNADGTLAGVEVDLGAFYRGEDVMAAHIADAIKNGQRLIDEAIAIVVTRQRNERRHGQTGETATAEPPPDTVNVTLDGSGRLLDLTVKPGSFAVHTPDSFGAAVVEAHNRAKGQRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6B7</accession>
    <name>D3Q6B7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017863.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2613"/>
    <dbReference type="EnsemblBacteria" id="ADD42292">
        <property type="protein sequence ID" value="ADD42292"/>
        <property type="gene ID" value="Snas_2613"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2613"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107911_0_0_11"/>
    <dbReference type="OMA" id="IAWRAYR"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="23445" checksum="A4E59F9322AC7D83" modified="2010-04-20" version="1">MTIGKGKGKRAEKAQRTRAKILTAARDLFVEHGYGTTALQDVADRAEVAVQTIYFTFRNKRTLLKEVVDVAIAGDAEPVATMDRDWFKESLATPTAREQLDIHVDGSRRILERVAPITKVLATAVAMDPEIATMWPQTTDPRYTVQLTAAETLITKPDAQPTLTATRAADLLYCLLSPELFLVFTADRGWPPADWAAWVTTTLRTQLCEPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6M6</accession>
    <name>D3Q6M6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoribonuclease YbeY</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ybeY</name>
        <name evidence="8" type="ordered locus">Snas_4626</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019840.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4626"/>
    <dbReference type="EnsemblBacteria" id="ADD44269">
        <property type="protein sequence ID" value="ADD44269"/>
        <property type="gene ID" value="Snas_4626"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4626"/>
    <dbReference type="eggNOG" id="COG0319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106710_3_2_11"/>
    <dbReference type="OMA" id="RMRIHPL"/>
    <dbReference type="OrthoDB" id="1830156at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00009">
        <property type="entry name" value="Endoribonucl_YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020549">
        <property type="entry name" value="YbeY_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46986">
        <property type="entry name" value="PTHR46986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00043">
        <property type="entry name" value="TIGR00043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01306">
        <property type="entry name" value="UPF0054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="156" mass="16871" checksum="1B63B17C605355F6" modified="2010-04-20" version="1">MPIEVANESGAEVGTESICDVARHALSEMGVHPLADLSILVVDETYMSELNHRWMGAAGPTDVLAFPMDELSVGRGPSNDSEPAAETLLGDVVLCPEVAERQAAKAGHSTADELHMLTVHGVLHILGYDHAEPDEAKQMFGLQQSLLDSWRRERTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Z3</accession>
    <name>D3Q6Z3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell division FtsK/SpoIIIE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0679</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015963.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0679"/>
    <dbReference type="EnsemblBacteria" id="ADD40392">
        <property type="protein sequence ID" value="ADD40392"/>
        <property type="gene ID" value="Snas_0679"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0679"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003134_1_0_11"/>
    <dbReference type="OMA" id="DGIYDPP"/>
    <dbReference type="OrthoDB" id="7548at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023836">
        <property type="entry name" value="EccCa-like_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023837">
        <property type="entry name" value="EccCb-like_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03924">
        <property type="entry name" value="T7SS_EccC_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03925">
        <property type="entry name" value="T7SS_EccC_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="6">
        <location>
            <begin position="463"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="6">
        <location>
            <begin position="831"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="6">
        <location>
            <begin position="1115"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="728"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="740"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="486"/>
            <end position="493"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="849"/>
            <end position="856"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="1132"/>
            <end position="1139"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1335" mass="146440" checksum="0FF7E5A7749CACE2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7A4</accession>
    <name>D3Q7A4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2698</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017946.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2698"/>
    <dbReference type="CAZy" id="GH43">
        <property type="family name" value="Glycoside Hydrolase Family 43"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42375">
        <property type="protein sequence ID" value="ADD42375"/>
        <property type="gene ID" value="Snas_2698"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2698"/>
    <dbReference type="eggNOG" id="COG3507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009397_8_2_11"/>
    <dbReference type="OrthoDB" id="442641at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="3">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="369" mass="39633" checksum="D71BAE62E9BD5ABF" modified="2010-04-20" version="1">MSARDVMWLIIAADCLPAEPEFASLALKPTEEESEPPMFTSALSFVRRRKVLAIGVVVAVAASTVACIGLGAVTQAEDAQTKAAKVQKVIDKNFADPEVIKVGNRYYAYATNNKRNLPVATADKPRGPWKFTGADGMPKLGAWAKPGRTWAPDVSRRPDGSFLLYYTAHHAKSGQQCIGAATASKPEGPFTAVGNAPLVCPTKQGGAIDAGSYSEGGKHWIMYKAENNVIGKPPVIYMHQTGPKGLKLLGKRFAILRNDRAVERGIIEAPVMVKRGGNYILFYAGDHFARNTYFTGYAVAKKITGPFKKADKPLLSMKGLGGAVKGPGGADVVTGPNGVDHIFFHGLVGKARHMYRAELGWVKGRPVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7W0</accession>
    <name>D3Q7W0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0753</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016036.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0753"/>
    <dbReference type="EnsemblBacteria" id="ADD40465">
        <property type="protein sequence ID" value="ADD40465"/>
        <property type="gene ID" value="Snas_0753"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0753"/>
    <dbReference type="eggNOG" id="COG1649">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057304_0_0_11"/>
    <dbReference type="OMA" id="NAYGDRY"/>
    <dbReference type="OrthoDB" id="538762at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="379" mass="40274" checksum="6419B935440671B3" modified="2010-04-20" version="1">MRISGHAYPWDVIGDPSFVDRVAEVDVDGVTLAAAYHSARAATPLHPVRQVVDARYAALYRPVRESVWAGRRLRPAEPDWVDGRDSYGEAAGILTDNGIPVTPWIVLTHATRLGQAFPDLAVTNCFGETYPYALCPAHAEVREYAATLAAEVLRDVPVHEVSLEACGQLGVNHLSHHDKTGGAWSPAAVRWLSVCCCSGCRSGWARHGLDPDTVVAALRDAVRGEAAETARPVPSDMAQTLLSVRHDATDRLRAETLAAVRQAAPGVPVVLHANPDPWATGASPGLTPTAAKDVDALLVPAWPTAPATTETVASAMASGVPVDAYVTVLPPADLDELPSHIGRLAEAGVRGLNLYHLGLAPRHGLRAYTEIRDAMRAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7W9</accession>
    <name>D3Q7W9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator, Crp/Fnr family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0762</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0762"/>
    <dbReference type="EnsemblBacteria" id="ADD40474">
        <property type="protein sequence ID" value="ADD40474"/>
        <property type="gene ID" value="Snas_0762"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0762"/>
    <dbReference type="eggNOG" id="COG2905">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056341_0_0_11"/>
    <dbReference type="OMA" id="QGGTYRV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045641">
        <property type="entry name" value="MmpI-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19307">
        <property type="entry name" value="PCLP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="98"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="471" mass="52806" checksum="B25287040FD752EE" modified="2010-04-20" version="1">MGEEMPDISTMSEQEQQAQSLSTAAARNLATTTKSTPQMQGISDRWLLRVLPWVQTNGGAYRVNRRLTYTVGDGRVTFTNVGSEVRVVPPELRELPPLRTYEDDEVLQTLAGRFVQQEFEPGAVIVEPGRAIDEVYLIAHGKANKVGTGAYGDDTILGVLADGQYFGEESLTEDDAQWGYSVKAVTACTVMMLPRQSFQDLMEQSEDLRDHIDDFREFTHHRHNQHGEAEVAVSAGHSGEVELPGTFVDYELSPREYELSVAQTVLRVHSRVADLYNEPMNQLEQQLRLTIEALKECQENELINNKEFGLLHNADFKQRISTRTGPPTPDDLDELLCRRRRTNVMLAHPQTIAAMGRECNKRGIYPQSIDFHGHMMPTWRGVPVLPCNKIPVTENRMSSIIAMRLGEESQGVIGLHQTGIPDEYEPGLSVRFMNINEKAIMSYLVSAYYSAAVLVPDALGVLENVEIGRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q884</accession>
    <name>D3Q884_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2782</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2782"/>
    <dbReference type="EnsemblBacteria" id="ADD42458">
        <property type="protein sequence ID" value="ADD42458"/>
        <property type="gene ID" value="Snas_2782"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2782"/>
    <dbReference type="HOGENOM" id="CLU_2958563_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="59" mass="6446" checksum="8B48A0269969A38C" modified="2010-04-20" version="1">MLRQRYIEFGETGDMGHVDGSNRARISGIGPGDRDGEVVMRENLTNLERSAVEPAVSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8A8</accession>
    <name>D3Q8A8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018053.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2806"/>
    <dbReference type="ESTHER" id="stanl-d3q8a8">
        <property type="family name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42482">
        <property type="protein sequence ID" value="ADD42482"/>
        <property type="gene ID" value="Snas_2806"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2806"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_13_3_11"/>
    <dbReference type="OMA" id="THETTIH"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="38"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="284" mass="31096" checksum="F984658E585F33E0" modified="2010-04-20" version="1">MRNPETPAVRDWTLSRTYPSDSGTVAWERFGEPDAPPVVLLHGTPFSSFVWRDIAAALAHDHRVYVWDMPGYGQSEKTPDKDLSLPALGRIFAELLQHWSLSSPAVIAHDTGGGVALDAHVTHGARYDRLALVDAVALSPWGSPFFRAIDGHTEVFAGLPGTLHEALMREYLNLASGPGLHPATLDGLLAPWLGTDGQAAFYRQLAHRGADEPYTDRIKDGYPTITIPVRLFWGTEDTWIPVERARELTELIDGSRLRMLPGAGHLSPVDNPAALTAGLVEFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8F7</accession>
    <name>D3Q8F7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2856</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2856"/>
    <dbReference type="EnsemblBacteria" id="ADD42531">
        <property type="protein sequence ID" value="ADD42531"/>
        <property type="gene ID" value="Snas_2856"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2856"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_0_11"/>
    <dbReference type="OMA" id="YKIVYFF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="86"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="35702" checksum="188C8F1B1492D50D" modified="2010-04-20" version="1">MTDSSQAIRRPAKSRKVTKIKQGRFILVFLALPILLYAYLVVFPLAEMFRISFTDWSGLSPDFSYVGFDNYIDMWSDPKGWVVPGFWHTGIMLLVLPVAVIVLALFFAFMLNVGGRGTGKITGVKGASFYKIVYFFPQVLSLIVIAILWRQIYAGPSDGGVLANVLSSLGLPSPESGFINEESMVLPAVIVAMIWASVGFYFVYFSAAMSGIPEELYEAARIDGASRTTTFFKITLPLLWDSVQTAWVYLGIIALDGFVLVYAMTPGAGGGGPNHASEVIGGVIFKFALGDGRNAGMGSALGVIVFLFMSVVTVVFLRATRRDRVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8I5</accession>
    <name>D3Q8I5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2884</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018130.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2884"/>
    <dbReference type="EnsemblBacteria" id="ADD42559">
        <property type="protein sequence ID" value="ADD42559"/>
        <property type="gene ID" value="Snas_2884"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2884"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_11"/>
    <dbReference type="OMA" id="RYMAFEL"/>
    <dbReference type="OrthoDB" id="1821409at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="254" mass="25954" checksum="E4067CB898ED258A" modified="2010-04-20" version="1">MTDLKNKTALVTGASRGIGRAIATRLAADGARVGVHYAGDEAAAHHTVERIERAGGTAFPLRADLGEPDGVDTLIAGLEAGLAGRRLDILVNSAAVPPAGPIQDDTPNSFDTVFAVNVKAPYFTVQKALPLLNDDGRVINLTSAVTRIANPTQTSFAMAKGALATMTLTLASQLGVRGITVNAVAPGVTRTETNTAVIASLGPEAQFAAITALDRLGEAADVADVVAFLASGDARWITGQTIDASGGLYLGLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8M6</accession>
    <name>D3Q8M6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">D-malate dehydrogenase (decarboxylating)</fullName>
            <ecNumber evidence="5">1.1.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_4827</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-malate + NAD(+) = CO2 + NADH + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:18365"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15588"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.83"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.83" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020039.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4827"/>
    <dbReference type="EnsemblBacteria" id="ADD44468">
        <property type="protein sequence ID" value="ADD44468"/>
        <property type="gene ID" value="Snas_4827"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4827"/>
    <dbReference type="eggNOG" id="COG0473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031953_0_1_11"/>
    <dbReference type="OMA" id="GTSMFEP"/>
    <dbReference type="OrthoDB" id="1551125at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046553">
        <property type="term" value="F:D-malate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011829">
        <property type="entry name" value="TTC_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02089">
        <property type="entry name" value="TTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="7">
        <location>
            <begin position="5"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="349" mass="37574" checksum="FAC520D1E2FC9E60" modified="2010-04-20" version="1">MTTHRLAVIPGDGIGTEVTPAAQSVLDAVAARHGFGFDYREFDWSCERYRTEGAMMPADGLDRLRDHDAILLGAVGSPGVPDHVSLWGLLIPIRRTFRQYVNLRPVRCFDGVESPLRNADVDLVVVRENIEGEYSQIGGRINSGFPDEMAVQETVFTRVGVSRIADYAFRLATTRRHRLTSATKSNGIVHTLPFWDEVVAERAQGFPDVDWDAEHIDALCAKVVLDPGRFDVIVGSNLFGDILSDLTAAVAGSIGIAPSANLNPERDFPSMFEPVHGSAPDIAGRGVANPIGAIWSAAMLLDHLGHPEAATEVVDAIAAVLSETPLRTPDLGGTATTSEFTAAIVKRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q908</accession>
    <name>D3Q908_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Integrin alpha beta-propellor repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0906</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0906"/>
    <dbReference type="EnsemblBacteria" id="ADD40617">
        <property type="protein sequence ID" value="ADD40617"/>
        <property type="gene ID" value="Snas_0906"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0906"/>
    <dbReference type="eggNOG" id="COG5555">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044344_0_0_11"/>
    <dbReference type="OMA" id="HWAVEAW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01839">
        <property type="entry name" value="FG-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00191">
        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0401">Integrin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048961" evidence="4">
        <location>
            <begin position="32"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="493" mass="50649" checksum="2BCD679A39B8F4C2" modified="2010-04-20" version="1">MSKKVARRVAASIMIAALPVALVQAAGPASAGEFVADPINDFDCDGQRDALDADSAASVGGHDAAGAVRVQYSGTAAAITIDQSTPGIAGSPETEDQFGTEVTAYDENGDGCDDLVIGASYEDLVDEGGEEQADAGMIWMIPGSAAGLDTQASTSLNLNSPGVPGSIAEYQWFGRTLSSGETQGGEPYLVAASPGYRTGSTQWAAGAVYYLRGDETYRITQDSPGVPGTAESYDYFGERIAVTDRYVAISAPGESIGSKSNAGMVHVFDHNLQGGVLTTVGAFHQDSPGISGTTETGDLFGDGLAVIGYRASASAPVSALVSAGSPGEAIGSSGGYTGMAHLIRVSSVNDLAQVSSVHQDSPGVLDVAEFNDGFGADTALATSKDDGIGSPATTHWAVEAWEFEDDGQGGENDNPQVHVFANLTDPGDGDRLIAGNDYGLPLASTPVIRSLDASDTYLYLTIPTDPTAVYGVPWQNILGGGSEETVIHRVDPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q951</accession>
    <name>D3Q951_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Lipopolysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_0949</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016231.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0949"/>
    <dbReference type="EnsemblBacteria" id="ADD40660">
        <property type="protein sequence ID" value="ADD40660"/>
        <property type="gene ID" value="Snas_0949"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0949"/>
    <dbReference type="eggNOG" id="COG0489">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_475420_0_0_11"/>
    <dbReference type="OMA" id="IQKNIAM"/>
    <dbReference type="OrthoDB" id="537895at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003856">
        <property type="entry name" value="LPS_length_determ_N_term"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02706">
        <property type="entry name" value="Wzz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Wzz" evidence="9">
        <location>
            <begin position="11"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="498"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="145"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="509"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD40660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="561" mass="57962" checksum="F4FF3D3F3921FE7F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q985</accession>
    <name>D3Q985_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2892</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018138.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42567">
        <property type="protein sequence ID" value="ADD42567"/>
        <property type="gene ID" value="Snas_2892"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2892"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="RANEWET"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="5">
        <location>
            <begin position="12"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="340" mass="36040" checksum="9CA818A8034ED077" modified="2010-04-20" version="1">MTTASPAGKRPAVMTDVARLAGVSHQTVSRVLHDSSQVRPETRERVLRAIEELDYRPNAMARGLVSRRSTMIGVITFDTILFGPASTLLGIERAARAKGYGVSIATLEKLDRSSVVEAANTLANQGVSGIVIIAPQTAVSSALHSMPRNLTAVAVECGPDSGLPAVSVDQVGGAAQATAHLLELGHKTVWHVSGPGDWLEARDRIEGWRSILERHGAVEPPVITGDWSARSGYAAGAMLAAQPDVTAVFAANDQMALGMLRAFYEKGLRVPDDVSVVGFDDIPEAPFLSPPLTTIRQDFDEMGRTAIATLLAILDGDSDPRPEPIASTLVVRESTGAPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9B6</accession>
    <name>D3Q9B6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018169.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2923"/>
    <dbReference type="EnsemblBacteria" id="ADD42598">
        <property type="protein sequence ID" value="ADD42598"/>
        <property type="gene ID" value="Snas_2923"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2923"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_11"/>
    <dbReference type="OMA" id="GPRMPRD"/>
    <dbReference type="OrthoDB" id="1180629at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="352" mass="37524" checksum="474FFF37B3DF5855" modified="2010-04-20" version="1">MRVLVTGGAGFIGSRIATALRQAGHDVVIADVLLAAAHGPHPRKDHPHMLCADVRDRGAMRRALRHVDVVCHQAAMVGLGNGFADACDYVDCNDLGTAALLSAMADAGVRRLVLAGSMVVYGEGVYHCAEHGQVRPGPRQVGDLDAGRFEPPCPHCGEALSPGLVEETATIDPRNVYAATKIAQEYLASAWARACAGRVISLRYHNVYGPGMPRDTPYAGVASFFRSALENGEPPKVFEDGAQRRDFVHVRDIASANLAALDAVYANIPEGTLRPYNVASGTPHTVGEMAAELAGFFGGPEPVVTGEYRLGDVRHITASTRRIRSELDWKPRVDFRKGVAEFAAAPLRGAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9E1</accession>
    <name>D3Q9E1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chitin-binding domain 3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2948</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018194.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2948"/>
    <dbReference type="CAZy" id="AA10">
        <property type="family name" value="Auxiliary Activities 10"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42623">
        <property type="protein sequence ID" value="ADD42623"/>
        <property type="gene ID" value="Snas_2948"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2948"/>
    <dbReference type="eggNOG" id="COG3397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039396_1_0_11"/>
    <dbReference type="OMA" id="ADWPITH"/>
    <dbReference type="OrthoDB" id="1005693at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049663" evidence="2">
        <location>
            <begin position="38"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-4" evidence="3">
        <location>
            <begin position="38"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="306" mass="32367" checksum="058A413ECDA822AD" modified="2010-04-20" version="1">MPRSPNPPVLRSLLAAAAAILVATGVTLFATVTPASAHGVTMMPGSRTYLCYLDGLTDTGEIKPDNPACADAVADGGATPLYNWFAVLDSNAAGRNVGYVPDGTICSAGDKSPYDFAAYNQARADWPITHLTSGASIQVRHSNWAAHPGAFHMYITKPGWDPTRPLAWSDLEPFWSATDPPQSGGPGGFNYYHWNVDLPQRSGQHLIFTQWVRSDSAENFFSCADVVFDGGNGEVTGIDAEVDSVTAMSWTASGHDHAGTGDAAAATPTPAQGSLWTSLWPVGAIIAFALIAALVANIRARRHRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9J5</accession>
    <name>D3Q9J5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018248.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3006"/>
    <dbReference type="EnsemblBacteria" id="ADD42677">
        <property type="protein sequence ID" value="ADD42677"/>
        <property type="gene ID" value="Snas_3006"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3006"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_1_0_11"/>
    <dbReference type="OMA" id="PRALEYM"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="6"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="404" mass="43795" checksum="B886FE961A91903B" modified="2010-04-20" version="1">MTNRTALISGASIAGPALAYWLNHFGFDVTVVEAAPAPRPGGYKVDLRGVAVEAVDRMGIGEAVRARDTAIRGGQWVTTKGKTLATLGPDLIGFRDPGDLEIMRGDLSDLLREATERTVEYRYGDVITAIEDTPDAAIVHFRHAASQRFDIVVGADGLHSGTRAVAFGPEDRYSRPIGMSVAVFNAPNRLGLDHWDMACSATGHTTNLYAFGPDQPAYAQLFFPTPAEVPDRHDRAAQERVLREAFGGHGWELPHLLAALPEAPELYFDHLAQIHMDTWTSGRTVLLGDAAYCPSPASGQGTGMALVGAHVLAHALAAEPDHRAGFAVYERRMRHFVDINQKLGRDVAAKLVPNTRFAAMAQRVMMRMLPYMPGKNAVLEGVMKPIREAANAIALDETAPMSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9L6</accession>
    <name>D3Q9L6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4921</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020133.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4921"/>
    <dbReference type="EnsemblBacteria" id="ADD44562">
        <property type="protein sequence ID" value="ADD44562"/>
        <property type="gene ID" value="Snas_4921"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4921"/>
    <dbReference type="eggNOG" id="ENOG5032Z5G">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133135_2_0_11"/>
    <dbReference type="OMA" id="QMERALY"/>
    <dbReference type="OrthoDB" id="2048663at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021401">
        <property type="entry name" value="DUF3040"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11239">
        <property type="entry name" value="DUF3040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="134" mass="14879" checksum="00C728AC9FE9188D" modified="2010-04-20" version="1">MPLSEHEQRVFDEIERSLADDPKFASAVRAHDPRHRGRRRMIIGGLISVVGLIVMVLGVMNNSLWIGAVGAVVAFVGILVALHIQRKGSGELSAVGGKARRRTGKPTKRHPGGGSSWGDRLEERWRRRRDNGWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9R1</accession>
    <name>D3Q9R1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4969</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4969"/>
    <dbReference type="EnsemblBacteria" id="ADD44607">
        <property type="protein sequence ID" value="ADD44607"/>
        <property type="gene ID" value="Snas_4969"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4969"/>
    <dbReference type="HOGENOM" id="CLU_2318748_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="99" mass="9952" checksum="8FCD86D21C6F458A" modified="2010-04-20" version="1">MTTLNCATWTWRNSSALPKRHQADDDTVGSLASAGTGLLKFLGVPVNSPLGAFLGGGGGGGGGGGGWFVDKTVDVVGRNADDFASPYGAATILGKVTPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Y5</accession>
    <name>D3Q9Y5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0987</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EccE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016268.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0987"/>
    <dbReference type="EnsemblBacteria" id="ADD40697">
        <property type="protein sequence ID" value="ADD40697"/>
        <property type="gene ID" value="Snas_0987"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0987"/>
    <dbReference type="eggNOG" id="ENOG50331Q0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043760_0_0_11"/>
    <dbReference type="OrthoDB" id="832050at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021368">
        <property type="entry name" value="T7SS_EccE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11203">
        <property type="entry name" value="EccE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="392" mass="41686" checksum="8BE6A0217B0B58C1" modified="2010-04-20" version="1">MTTIGLATRRSGLGLGPVRMAQLIVCEVAAAVAFLSWMFPTPTPYIVSGVALLVVITVVVLSIRGLGYTLLMSLRNYKLRRGYEATIEGVGALSALAPGLRIVGVVERDTEYGVAFDGTGWFTGIALRHDDPTSPGGLDAGSLGVITSVLNDPGAAVSGIQLVNHLVPAPSAEVAPQSPCTRSYVELLGDDPVVSHQMTWLAVRLDIPTAARTAAARGGRSIGARRAVAAMTMRVAKRLTDAGVKHRILGPDSLRVALTHSVSGESVSAAMVQQAGERWDLWRLGMLAQVNFGVEGRISDIDKLRRLWISMAVLSTSFVTIATTFHPPEDTRGEGVWLRSMLRVAYDEELNADVPTELEDAAAQCGVRVWRCNGRQASATYASAPTGGAFPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA19</accession>
    <name>D3QA19_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40731">
        <property type="protein sequence ID" value="ADD40731"/>
        <property type="gene ID" value="Snas_1021"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1021"/>
    <dbReference type="HOGENOM" id="CLU_1219105_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="227" mass="23493" checksum="06D402382D1C6450" modified="2010-04-20" version="1">MDMTESPQQPGYSAAQQQQAAAYAAQQQQQAYAQQAYAQPAPNVFDKLPMNIVTFGLAAGGAVVLFIGLLIAGSKSDSILDVNSSVLGASVALMVATAIAITTGPKYRNAYRLITLGLAIVALGSTVGALIGDGELSNADGAVVIGRLLFVAALGLFTASTFTMAEPVAANPQQLAAMQAAQAQQAAQQQAAAQQAAAQQQYQATQAIQQQTGEQPTTWQQQQPPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA37</accession>
    <name>D3QA37_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1039</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016320.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1039"/>
    <dbReference type="EnsemblBacteria" id="ADD40749">
        <property type="protein sequence ID" value="ADD40749"/>
        <property type="gene ID" value="Snas_1039"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1039"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_4_11"/>
    <dbReference type="OMA" id="LVICNSY"/>
    <dbReference type="OrthoDB" id="664909at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="335" mass="35111" checksum="DC648A3CD6DBFC34" modified="2010-04-20" version="1">MDHTRPTTLADVAKRAGVSVATASRVLNGSPHKVSAGLAAKVRAIADELRYAPNAQAQGLARSTSRVVALLLHDITDPYFGQIAQGVLAEAAERDVCVVIAETGIDPDNERDQLASLGSLRPRAAIMVGSRTTETDAEQRLSRALEDLRAIGTAVVNVGQPSLPGSCVHPLNREGAKELATHLAGLGHRRFALVTGPASLRVVAERREGFVDGLPVEAGVEIIDAPFSRDGGHDAGMRFAAMSNRASAVFVTSDVMASGFYAALRESGLSIPEDVSVAGFDDVPVAADLYPALTTVRLPLSGMGAQALRLALDGEEEQTVTIEPELIPRASTARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAQ4</accession>
    <name>D3QAQ4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5064</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020271.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5064"/>
    <dbReference type="EnsemblBacteria" id="ADD44700">
        <property type="protein sequence ID" value="ADD44700"/>
        <property type="gene ID" value="Snas_5064"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5064"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112485_0_0_11"/>
    <dbReference type="OMA" id="FREPHDG"/>
    <dbReference type="OrthoDB" id="1551670at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="213" mass="24513" checksum="4BC2BEF0DBF61A85" modified="2010-04-20" version="1">MTETEAPRTNANDLPEAELIAWYGPWEPLTLNEIRAVFDGTPVRWWVAGGRVIDAVTGTAREHGDVDVAIAREDLDIVRERVPDWQLWHAHSGSLQPLFPGDPLMEGREGLWVRRDATQPWILDLLLSPTDGVDWIFKRDHSIRLPLSEAVIRIDDMPYLAPQCVLLYKARHMRDKDRRDFDVTLPHLDTAARAWLATALDKHLPGHEWRQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBQ1</accession>
    <name>D3QBQ1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type III effector Hrp-dependent outers</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_3263</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the four-carbon acid sugar kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018504.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3263"/>
    <dbReference type="EnsemblBacteria" id="ADD42933">
        <property type="protein sequence ID" value="ADD42933"/>
        <property type="gene ID" value="Snas_3263"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3263"/>
    <dbReference type="eggNOG" id="COG3395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029424_0_1_11"/>
    <dbReference type="OMA" id="TIYCPAF"/>
    <dbReference type="OrthoDB" id="771666at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037051">
        <property type="entry name" value="4-carb_acid_sugar_kinase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010737">
        <property type="entry name" value="DUF1537"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031475">
        <property type="entry name" value="NBD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042213">
        <property type="entry name" value="NBD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17042">
        <property type="entry name" value="NBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07005">
        <property type="entry name" value="SBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SBD_N" evidence="7">
        <location>
            <begin position="7"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="NBD_C" evidence="8">
        <location>
            <begin position="256"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="454" mass="46544" checksum="8F44EB785B10A0B1" modified="2010-04-20" version="1">MTPPHAILVIADDLTGANATAAGFARAGLRAVTVGADQPGTVIAEFTNRFDAVVVCTDTRHAPPAEAAARVEAAIAAAPPVRLVCNRVDSTLRGNLGASTAAVLRAVARRTATPTVALFLPAHPAAGRQTVEGNQLLDGVRLENTELARDPRTPLRTSDVADLLTQQAALRIAHIPLSLVTGDPVRLRKAVATRVAAGAQVIIGDALTVEHLRRVTDAAVAAAPEVEWVGVDPGPGAVELARAKGLTGHDDTAPLLAVSGSATALTRQQLARLRETRPVTVVRPVYSGDTVLPDLEPTAKQLAAALAQADSGDTVLLATALDDGDIVDIDPADAARLPQLLAGAVRRALAERAVGGLFVTGGDVTAAMTAELGAAGIEVEQELVPLAVAGSVVGGDWDGLPIVTKGGLVGDPATTVECVDHLRRTVQANRRRVRAAAVGHHDHTTGRTEPGGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBR0</accession>
    <name>D3QBR0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobalamin (Vitamin B12) biosynthesis CbiX protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5164</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020370.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5164"/>
    <dbReference type="EnsemblBacteria" id="ADD44799">
        <property type="protein sequence ID" value="ADD44799"/>
        <property type="gene ID" value="Snas_5164"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5164"/>
    <dbReference type="eggNOG" id="COG2138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056929_3_0_11"/>
    <dbReference type="OMA" id="PCRVSYA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002762">
        <property type="entry name" value="CbiX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01903">
        <property type="entry name" value="CbiX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="301" mass="30431" checksum="3D3B3DAA4245B92B" modified="2010-04-20" version="1">MLVAHGSPDHRSRAVVRDIAAAANATAAFLDFDAPHPVAVLKGLADAGHRRAILVPLLLTHAYHGRVDVPRIAFEAMAQRPHLSVEVTPPVGGPHLLPALRRGLPEAEAFGHGRDPSVIGAADLGLRTVDAVGREGAVGRGSSVGVSGRERLAANAPFAVTSGSGREAADAVVLASAGTRDVATLDSLGKLAAELGRELGLPAAAAYASAAKPTVAEAVAELRGRGARRVAVASYFIAPGVLHDRVASAAAEAGAFAVTPPLGACPELVAAIARRAAAVTQATAEPAPGRCGELLLAFRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBX5</accession>
    <name>D3QBX5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020435.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5230"/>
    <dbReference type="EnsemblBacteria" id="ADD44864">
        <property type="protein sequence ID" value="ADD44864"/>
        <property type="gene ID" value="Snas_5230"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5230"/>
    <dbReference type="eggNOG" id="COG2050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089876_5_0_11"/>
    <dbReference type="OMA" id="KINYVRP"/>
    <dbReference type="OrthoDB" id="1814691at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="49"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="157" mass="16515" checksum="5768F9BD62893DA0" modified="2010-04-20" version="1">MESDELTAFAHSVFNAQPFSRFIGAELVAVSRGTAEIRVKNRPDLQQQHGYLHGGVISYLADNCLTFAGGLALGGDALTSEYKINYASPAKGDVIIARAESLVTTKRQAVCQCSIYSQKDGEEQLVAVAQGTIVKIQSAAREATSLTASTAASGSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBZ7</accession>
    <name>D3QBZ7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_5252</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GtrA family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020457.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5252"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44886">
        <property type="protein sequence ID" value="ADD44886"/>
        <property type="gene ID" value="Snas_5252"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5252"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2246">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_3_0_11"/>
    <dbReference type="OMA" id="FFDTEML"/>
    <dbReference type="OrthoDB" id="1064289at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04188">
        <property type="entry name" value="DPG_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035518">
        <property type="entry name" value="DPG_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="8">
        <location>
            <begin position="27"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="9">
        <location>
            <begin position="289"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD44886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="416" mass="44935" checksum="1884D49C3D8015D8" modified="2010-04-20" version="1">MEDTAIRSQGLPVRAPIPAGHYEPVIDVVIPVYNEQDDVEASVRRLHTHLARTFPYGYRITVADNASTDATPAIAARLAAELAQVEFVRLPEKGRGRALRQVWSHSTVPVLVYMDVDLSTDLNALLPLVAPLISGHSDLAIGTRLARGSRVVRGGKREFISRTYNAILKGGLAAGFSDAQCGFKAIRADVAAELLPLVEDTGWFFDTELLVLAERAGLRIHEVPVDWVDDPDSRVDIVRTAVDDLKGVWRVGRALASGALPLSRLRRPFGDDPRDRETSGGLVRQLLSFCVIGILSTLFYLVLYTVFRDGLGPQVSNMVALLVTAMASTAVNRRFTFGVRGRDGAVRQQAQGLAVFAIGLTLTSGSLAALEIASPTAGQTTELAVLVVANLAASLLKFLLFRGWVFPAARTESEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC32</accession>
    <name>D3QC32_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SMP-30/Gluconolaconase/LRE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0044"/>
    <dbReference type="EnsemblBacteria" id="ADD39766">
        <property type="protein sequence ID" value="ADD39766"/>
        <property type="gene ID" value="Snas_0044"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0044"/>
    <dbReference type="eggNOG" id="COG3386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036110_3_1_11"/>
    <dbReference type="OMA" id="QKIWAFD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005511">
        <property type="entry name" value="SMP-30"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01790">
        <property type="entry name" value="SMP30FAMILY"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGL" evidence="1">
        <location>
            <begin position="22"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="296" mass="31362" checksum="CBB7868F7D67838F" modified="2010-04-20" version="1">MVREDPTVADQPALWTDYACELGEGARWVDGRLIHVDILGGFLFTVDGSRPHTGEPEVLVDAGLPLGAVAPVADRPGTWIAAVGHGIALLTESGTEWLAEFGTPEAMRVNDAVADPGGRFWAGTLSYDNTPGAGALYRVDPDGTVVTALSDLTIPNGPAFSADGTLMYLSNSAHGSVDVYPVDPATGYLGAPDPFARLESGLTPDGLTVDDEGCVWVAVWDGSQVRRYRPDGSLDRTLSLPTSRPTSCCFGGPAMNRLFVTTAAYDLRDDAAGKVYAFDLDVTGRAADTFRPREVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTZ4</accession>
    <name>D3PTZ4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015323.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0030"/>
    <dbReference type="EnsemblBacteria" id="ADD39752">
        <property type="protein sequence ID" value="ADD39752"/>
        <property type="gene ID" value="Snas_0030"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0030"/>
    <dbReference type="eggNOG" id="COG1040">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1711149_0_0_11"/>
    <dbReference type="OrthoDB" id="1216529at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="126" mass="13960" checksum="7058D360EB199701" modified="2010-04-20" version="1">MTVPSSDGRENHPLQEIAGISTIRQLVPTINPAYSAKNRRFQLDAFRPFENDLTGSKVLVIDDTWVSGSTVQSLAHRVKRDGASTVVILTLGRWAVWDKPVWKSLIEQSINSATAFDVETCALNHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU00</accession>
    <name>D3PU00_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF418 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1236</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1236"/>
    <dbReference type="EnsemblBacteria" id="ADD40946">
        <property type="protein sequence ID" value="ADD40946"/>
        <property type="gene ID" value="Snas_1236"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1236"/>
    <dbReference type="eggNOG" id="COG2311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039610_1_0_11"/>
    <dbReference type="OMA" id="MAWMVAR"/>
    <dbReference type="OrthoDB" id="1742337at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04235">
        <property type="entry name" value="DUF418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="DUF418" evidence="3">
        <location>
            <begin position="231"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="399" mass="41760" checksum="B3565E04A988296F" modified="2010-04-20" version="1">MTVSSSPAPGPFRNATKPSQRRLSPDLARGFMLLLIAMAYAPMHLEHKNVGGYGQKPGGGVADQVMSFLATLFLENRAFPLFGIMFGAGLVMLVSRQLKAGTPERDVRRLLRRRSLWLLLFGFVHATLVFSGEILAAYGVGGLVLAWLLFRGMTAVRVAAIVLCVYYGVVVTLAAGAIVTGAAASAEKASGLPGYTSVQDWIERLAAAPFAPLLNTLLFPMFLLVVLGIWFGKRGLLDDPAAHRRTLRWLAGCGISVSVLGALPLALVGAGVLDVSGSTHGLLFAAQILTGVAGGVGYAAAFGLLGARLQRRPGPVTRTLAAAGQRSLSVYLFASVGVAVILHPALLNLGAHTHRAGAMAVAFGVWLVAVLLAGRLAAAGRPGPADALLRGLVYRGSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU64</accession>
    <name>D3PU64_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription termination factor Rho</fullName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ATP-dependent helicase Rho</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rho</name>
        <name evidence="12" type="ordered locus">Snas_1301</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The homohexamer assembles into an open ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1301"/>
    <dbReference type="EnsemblBacteria" id="ADD41010">
        <property type="protein sequence ID" value="ADD41010"/>
        <property type="gene ID" value="Snas_1301"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1301"/>
    <dbReference type="eggNOG" id="COG1158">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016377_3_0_11"/>
    <dbReference type="OMA" id="TTDLMGA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008186">
        <property type="term" value="F:ATP-dependent activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01884">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036269">
        <property type="entry name" value="Rho_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011113">
        <property type="entry name" value="Rho_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004665">
        <property type="entry name" value="Term_rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46425">
        <property type="entry name" value="PTHR46425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07498">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07497">
        <property type="entry name" value="Rho_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00959">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68912">
        <property type="entry name" value="SSF68912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00767">
        <property type="entry name" value="rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51856">
        <property type="entry name" value="RHO_RNA_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 8" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Rho RNA-BD" evidence="11">
        <location>
            <begin position="214"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="30"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="144"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="341"/>
            <end position="346"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="353"/>
            <end position="358"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD41010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="597" mass="65723" checksum="61D9E83E21B7732F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUB5</accession>
    <name>D3PUB5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1353</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1353"/>
    <dbReference type="EnsemblBacteria" id="ADD41061">
        <property type="protein sequence ID" value="ADD41061"/>
        <property type="gene ID" value="Snas_1353"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1353"/>
    <dbReference type="eggNOG" id="COG3845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_92_0_11"/>
    <dbReference type="OMA" id="VGREMSH"/>
    <dbReference type="OrthoDB" id="551294at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="261"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="516" mass="55456" checksum="FB04C79B0270ADD2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUR4</accession>
    <name>D3PUR4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5304</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020509.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5304"/>
    <dbReference type="EnsemblBacteria" id="ADD44938">
        <property type="protein sequence ID" value="ADD44938"/>
        <property type="gene ID" value="Snas_5304"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5304"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_365576_0_0_11"/>
    <dbReference type="OMA" id="MDFGIAV"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="11"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="278"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="763" mass="82114" checksum="B75A8901839BEFD5" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUY8</accession>
    <name>D3PUY8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020583.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5380"/>
    <dbReference type="EnsemblBacteria" id="ADD45012">
        <property type="protein sequence ID" value="ADD45012"/>
        <property type="gene ID" value="Snas_5380"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5380"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_6_3_11"/>
    <dbReference type="OMA" id="EATHEFL"/>
    <dbReference type="OrthoDB" id="1772343at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="117" mass="12478" checksum="675A40C9BAAD9BDC" modified="2010-04-20" version="1">MTTAATSLSSEAQAFLKALASPTRQQIMFAFDGGGELTVGDVAERLELAQSATSTHLAMLRDAGILVARRDWKTVYYRANPAGFLKSLDDLRDYLMACCPPDCAASSQQAGDEAAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV17</accession>
    <name>D3PV17_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020612.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5409"/>
    <dbReference type="EnsemblBacteria" id="ADD45041">
        <property type="protein sequence ID" value="ADD45041"/>
        <property type="gene ID" value="Snas_5409"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5409"/>
    <dbReference type="eggNOG" id="COG2944">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095704_0_0_11"/>
    <dbReference type="OMA" id="KRLVQRW"/>
    <dbReference type="OrthoDB" id="1187580at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027910">
        <property type="entry name" value="YdiL_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="252" mass="27281" checksum="F6112CED8797DE62" modified="2010-04-20" version="1">MTNSTLQAIRKGLLLSQDEFARALREAGQRAGVPNDASKRLVQRWESGESASPRPVYARALESVTGLPITELGFAVPVPAARVTPNGQGGHDVAASGPDFEVIAPVAHAGKNATSTNYSGIWLSRYEYYSSGRGDTFIGVHYVLVLQHGDRLTARSLPGSSDSPLTMDLTVDGSVVTGTWVEQTHKDGYYRGARYHGAIQMIAEPTGRKISGKWLGFGKEMEVNSGPWALIFQDASTNKSTMNKYNKRPPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV39</accession>
    <name>D3PV39_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1385</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016663.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1385"/>
    <dbReference type="EnsemblBacteria" id="ADD41092">
        <property type="protein sequence ID" value="ADD41092"/>
        <property type="gene ID" value="Snas_1385"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1385"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="CDRELHL"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="22382" checksum="7A407550423AD77E" modified="2010-04-20" version="1">MNTSLQVEAVAVQYGHRHALSDVNITVPPGSVLAVTGASGSGKTTLLWVMAGLLAPTSGTVRLGGKDIQVREDAVTEGVHLIPQGNGLASVLTAHENVAVAMLAAGVDAAEATRRADAALDQLGVTAQAAQLAEELSGGQRQRVAIARGLALRAPVLLADEITSDLDVENRDLVLDLLRQEAKRGACVVFATNDTEAAATCDIVVHLADGRVEATPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVB2</accession>
    <name>D3PVB2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF418 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1461</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1461"/>
    <dbReference type="EnsemblBacteria" id="ADD41165">
        <property type="protein sequence ID" value="ADD41165"/>
        <property type="gene ID" value="Snas_1461"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1461"/>
    <dbReference type="eggNOG" id="COG2311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039610_1_0_11"/>
    <dbReference type="OMA" id="FGYGMMQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04235">
        <property type="entry name" value="DUF418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="DUF418" evidence="2">
        <location>
            <begin position="232"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="401" mass="42337" checksum="7C4570353F9832E8" modified="2010-04-20" version="1">MTTQATPVTLRGPTALSERAFAPDFARGMLLLFIVLSNTGLHLYGAGLVSDSTVDSVTRFLMPVFVDVRSYPLFAFLFGYGITQLATRQRGAGVEESRVRRLLRRRGWWLFGFGFVHAALLLGSEVLAAYGLIGLVLVGLFLKRSDRTLLVWAGIGGFILAVLFASSAVALVTTEPPSGSSGGADAPESMFGVDNGSWLVAGAGRLISWLFLLGVNGFGVVMPTAILLGMLAARRRVLEEPGRHLRLLYAMAIGGIGFGLCGSLPVALSGYTASDIHQSGYGLLLFGLQWSSGLAGGLGYVGLFGLLAHWLSSRAARGGPVLAITALGKRSLSGYLTHSVLMAPLLAAWGFGLGGELSRAGMAAFGIGLWLVTVVAAYLFERAGRRGPAEVLLRGLVYGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVC7</accession>
    <name>D3PVC7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016751.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1476"/>
    <dbReference type="EnsemblBacteria" id="ADD41180">
        <property type="protein sequence ID" value="ADD41180"/>
        <property type="gene ID" value="Snas_1476"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1476"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063440_10_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="26"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="109" mass="11937" checksum="DEDD6E1C42577E06" modified="2010-04-20" version="1">MSQKVKVTAAVATVLGSLMESPDADHYGLELMKSTGLPSGTLYPILVRLQRAEWLEACWEDVDASQAGRPARKYYRLTPDGTVAARRELTAMYQRLSRLPGIAQEGSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVK8</accession>
    <name>D3PVK8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">V-type ATP synthase subunit I</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_3458</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018693.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3458"/>
    <dbReference type="EnsemblBacteria" id="ADD43122">
        <property type="protein sequence ID" value="ADD43122"/>
        <property type="gene ID" value="Snas_3458"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3458"/>
    <dbReference type="eggNOG" id="COG1269">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_582544_0_0_11"/>
    <dbReference type="OMA" id="YGEFFGP"/>
    <dbReference type="OrthoDB" id="259071at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="PTHR11629"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01496">
        <property type="entry name" value="V_ATPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049276" description="V-type ATP synthase subunit I" evidence="9">
        <location>
            <begin position="33"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="469" mass="48954" checksum="8D58AE59826FB835" modified="2010-04-20" version="1">MPLSETMRPVRMRRVAIVAGQADLRAALAAVADTGTVQLDSTSWAESSAGPAGRALRAAHATVDSPALSEWEPDLDELVRGGRLDLLAGEAQLETHAAQAVRRGEFAALTGWLAESALPDLTARLSRLGAAVVPLPSPPGVDPPTLLPEGGPWRGSFTELVTTYGTLPYRDVDPTLPAAAAYVFMFGMMFGDAGHGLLLLLVALWLRFRPPRRLLWAVRAWPFVLAAGFTSVGFGVLYGEFFGPTGVLPVLWVAPLEQPMTLLWASVAVGAVLLAAAYAAAVVNRWREGGPRLAVYASSGGAGLTVFVGLGALAAGLLLHGYVLIGVGVCVTAVGLALSGVGFYAASGGGAGGMAQAGVEVFDAILRLGSNLFSFARLAAFGLTHAALAGLVWHGTTGLADGGLPGTIAAVLVFVLGNAVAFALEALVAAIQALRLEFYELFSRMFTGFGEPFHPWRIPIWTDMEEDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVM9</accession>
    <name>D3PVM9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018714.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3480"/>
    <dbReference type="EnsemblBacteria" id="ADD43143">
        <property type="protein sequence ID" value="ADD43143"/>
        <property type="gene ID" value="Snas_3480"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3480"/>
    <dbReference type="eggNOG" id="ENOG5033C4C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_849775_0_0_11"/>
    <dbReference type="OrthoDB" id="2092326at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="316" mass="34161" checksum="6D983D4C7C40D39D" modified="2010-04-20" version="1">MNRHDALERRYRRLLRFYPKEYRTERGKEIVDTYMEATPPERTTPGVADVGDVAKAGLRQRLRDAPEGLPGGLRLAAVVGLCLAVGIGAVFGPAMEILAREGEPATSWFTIPSFGPFLSPFVILWTLWLLVGVGAALLPGRITRRVVAGAVVATVAAELVTFFVGGLATDPLSMAALILFGVISLAWPEHPGPGARIAPLVAACAGIATTLGYAVAPPPFQVFGIVETPLLILLLAAVILFAEREVRSRRGSGQRWWAVAILAVPVSIILLRPVERLPFLDTMPFIPGAFWLLGLGLAIPIVSYLVAVRRHRLTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVS1</accession>
    <name>D3PVS1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3522</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018756.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43185">
        <property type="protein sequence ID" value="ADD43185"/>
        <property type="gene ID" value="Snas_3522"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3522"/>
    <dbReference type="eggNOG" id="ENOG502ZRGX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1517034_0_0_11"/>
    <dbReference type="OrthoDB" id="1950005at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046193">
        <property type="entry name" value="DUF6221"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19730">
        <property type="entry name" value="DUF6221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="177" mass="19744" checksum="AF13D06343E2B3F5" modified="2010-04-20" version="1">MTQLVDFIKARLNEDETWALAASRPPDGLGTQSTDATPDPVPGGVHWQWRHGNEYLSFKVPPSPEPGCVTGPGEVCWLSTVEQFPVPGGYDGETSPGLYSNGILEMDLEAAVHIARHDPAKTIRDVRAERRMLQRCIQVVDGSTKLNSPEVKLALYVIRMMALKHSRHADYQKEWRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVV8</accession>
    <name>D3PVV8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020650.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45079">
        <property type="protein sequence ID" value="ADD45079"/>
        <property type="gene ID" value="Snas_5447"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5447"/>
    <dbReference type="eggNOG" id="COG3797">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106303_2_0_11"/>
    <dbReference type="OMA" id="LHVTYFS"/>
    <dbReference type="OrthoDB" id="1382593at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012545">
        <property type="entry name" value="DUF1697"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36439">
        <property type="entry name" value="PTHR36439"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08002">
        <property type="entry name" value="DUF1697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008502">
        <property type="entry name" value="UCP008502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="174" mass="18969" checksum="5FF18FCA77293BE6" modified="2010-04-20" version="1">MATYVALLRGINVGGHNKLPMAELRDLFATLGHPGARTYIQSGNVVFDAEAEASDLERDIAAGIADRFGYTVAVMVRSREQLDAVLAAHPFGGRDLDPAKVAVVFLSATVDAVTVPEGYPEEAVSVGRELFIHYPDGMGKSKLDRSGFWKQLGDTKTTVRNWRTVTKLREMMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVY8</accession>
    <name>D3PVY8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GTPase Obg</fullName>
            <ecNumber evidence="6">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">obg</name>
        <name evidence="11" type="ordered locus">Snas_5478</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020680.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5478"/>
    <dbReference type="EnsemblBacteria" id="ADD45109">
        <property type="protein sequence ID" value="ADD45109"/>
        <property type="gene ID" value="Snas_5478"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5478"/>
    <dbReference type="eggNOG" id="COG0536">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011747_2_1_11"/>
    <dbReference type="OMA" id="VVFDWEP"/>
    <dbReference type="OrthoDB" id="603226at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036346">
        <property type="entry name" value="GTP-bd_prot_GTP1/OBG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015349">
        <property type="entry name" value="OCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="PTHR11702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09269">
        <property type="entry name" value="DUF1967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102741">
        <property type="entry name" value="SSF102741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03595">
        <property type="entry name" value="Obg_CgtA_exten"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51881">
        <property type="entry name" value="OCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="10">
        <location>
            <begin position="2"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="8">
        <location>
            <begin position="160"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="OCT" evidence="9">
        <location>
            <begin position="348"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="428"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="442"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="166"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="191"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="212"/>
            <end position="215"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="282"/>
            <end position="285"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="311"/>
            <end position="313"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD45109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="480" mass="50248" checksum="6377E3A807382143" modified="2010-04-20" version="1">MSSFVDRVVLHVQAGTGGHGCVSIHREKFKPFGGPDGGNGGHGGDVVLEVDPNVHTLLDFHFHPHAKAGNGKGGQGSNRNGAFGKSLHLKVPDGTVVQSADGEVIADLTGVGTSIVLARGGRGGRGNAALANAARKAPGFAELGEEGEALDAVLELKSVADVGLVGFPSAGKSSLIAALSAARPKIADYPFTTLVPNLGVVSAGETTFTIADVPGLIPGAAHGKGLGLEFLRHIERCAVLAHVVDCATLEPGRDPLSDIDALEHELAEYGGLTDRPRIVVLNKIDVPEAAELAELVRADVETRGWPVYEVSAVARKGLSTLTYALAAAVTAHRESQPRPEPTRIVLRPQGVDDSGFEIKETKDGVFHITGAKPERWVRQTDFSNDEAVGYLADRLAKIGAETALAKAGATPGCLVRIGAVEFEWEPTDPATIAMSGPRGTDPRFETDNRVSAADRLAARKARRATTEEPDSEDDAEEDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW03</accession>
    <name>D3PW03_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020695.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5493"/>
    <dbReference type="EnsemblBacteria" id="ADD45124">
        <property type="protein sequence ID" value="ADD45124"/>
        <property type="gene ID" value="Snas_5493"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5493"/>
    <dbReference type="HOGENOM" id="CLU_1453589_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="186" mass="20369" checksum="6798D7AAB71E88CB" modified="2010-04-20" version="1">MNDSNNETPTCNTNVNDCAPYEAPVYGPRATPSLHAATFVEMESASIYSLGYNLAGRLGDYDRNVELIKGQLTNNTEYDAAQGEVNPIARDKRWVHAVNAANYHTESMKGNAELLKTFRDGMDRLSRLTRIIVNEVGGIDAQNKMTLEDLEAKTGLNKNNATTVDHTYSPGSPTYNTGPGSNRPNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW18</accession>
    <name>D3PW18_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5508</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020710.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5508"/>
    <dbReference type="EnsemblBacteria" id="ADD45139">
        <property type="protein sequence ID" value="ADD45139"/>
        <property type="gene ID" value="Snas_5508"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5508"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="AFGPKVH"/>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="21"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="63"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="355" mass="38764" checksum="71786F6842419CBD" modified="2010-04-20" version="1">MSAMQNPTVATTDASGSAPLMEVSGLTKHFEVRRGLLASKAKVRAVDDVNFVVHKGESLGLVGESGCGKTTTGRMLVRLLEPTAGSLRFEGRDITKLKGQDLRKLRQDLQIIFQDPYASLNPRHTVGKIIATPLVVNNIEPPGGIKARVRELMELVGLNPEHYNRYPHEFSGGQRQRIGIARSLALKPKLVIADEPVSALDVSIQAQVINLLRELQRELDLSFVFIAHDLSVVRHFCDRIAVMYLGKVAEIGDRHQIYDTPSHPYTKALLSAVPDVTRLGAKGETRMKLTGDVPTPLNPPSGCRFRTRCWKAQDICATTEPPLQKVGTGAVAACHFPEVHGPESTNSGTVEGSME</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWU8</accession>
    <name>D3PWU8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020743.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5541"/>
    <dbReference type="EnsemblBacteria" id="ADD45172">
        <property type="protein sequence ID" value="ADD45172"/>
        <property type="gene ID" value="Snas_5541"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5541"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_11"/>
    <dbReference type="OMA" id="WINGASI"/>
    <dbReference type="OrthoDB" id="1821409at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="254" mass="26226" checksum="85172A8E8EB6091C" modified="2010-04-20" version="1">MNRIALVTGGSRGIGRGIAERLAADGVVVGVHYGSNETAAKETVAAIEAAGGRAFTVGARLGVPGDVDALFAAFTEGVKPYADEPHLDILVNNAGTNGPGSVDTATPEGYDAVMDLNLKAPFFTVQKALPLLRDGGRIINISSGASHATWKNDPAYAMTKAALDSFTRSLAAQLGPRDITVNSVGPGVIDTDMNASWLRDSPEGREAGAAWSVFKRVGEVDDVAEVVGFIASDKARWVTGQFIDATGGSLLIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXB9</accession>
    <name>D3PXB9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endonuclease I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016953.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1682"/>
    <dbReference type="EnsemblBacteria" id="ADD41382">
        <property type="protein sequence ID" value="ADD41382"/>
        <property type="gene ID" value="Snas_1682"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1682"/>
    <dbReference type="eggNOG" id="COG2356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019348_0_0_11"/>
    <dbReference type="OrthoDB" id="1114630at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007346">
        <property type="entry name" value="Endonuclease-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33607">
        <property type="entry name" value="PTHR33607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04231">
        <property type="entry name" value="Endonuclease_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048052" evidence="1">
        <location>
            <begin position="38"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="267" mass="29900" checksum="C115D39AB37FA4AD" modified="2010-04-20" version="1">MGKEWMPMRRTRTLAALAGAAVGATALILVPLATAQGHDAYEPPDGYYDAVEGMTGEELKAGLNDIISNNEQLSYDEARDALKETDADPADPSKVVLIYNGTSVPADDYDQWNREHVWAKSHGDFGTDIGPGTDVHHLRPANAVVNSTRNNLDFDMGGEEVADAPGNFYDSDSFEPRDEDKGDVARMILYMAVRYEGEDSYPDLEPNDEVENNEKPLHGRLSVLKQWNEQDPPSDFEKNRNEVIFEKFQKNRNPFIDHPEWVGEVWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXC7</accession>
    <name>D3PXC7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016961.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1690"/>
    <dbReference type="EnsemblBacteria" id="ADD41390">
        <property type="protein sequence ID" value="ADD41390"/>
        <property type="gene ID" value="Snas_1690"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1690"/>
    <dbReference type="eggNOG" id="COG4270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126433_7_0_11"/>
    <dbReference type="OMA" id="VRANWHR"/>
    <dbReference type="OrthoDB" id="2018019at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13564">
        <property type="entry name" value="DoxX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="134" mass="13868" checksum="67CCB8FDBFC8D689" modified="2010-04-20" version="1">MTTNTAPATTARPSRALNITLWTVQSVLAAFYAFAATPKLLGDPTTADMMAQIGFANWVGYFIGAAELAGAIGLLIPRLTSLAATGLALLMVGATVTNTFTMGAGAAAMTLVLAAVFATVAYARRSWITRPGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXF2</accession>
    <name>D3PXF2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1716"/>
    <dbReference type="EnsemblBacteria" id="ADD41415">
        <property type="protein sequence ID" value="ADD41415"/>
        <property type="gene ID" value="Snas_1716"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1716"/>
    <dbReference type="eggNOG" id="ENOG5031AT3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104624_2_0_11"/>
    <dbReference type="OMA" id="NDVWLHA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025492">
        <property type="entry name" value="DUF4383"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14325">
        <property type="entry name" value="DUF4383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="153" mass="16215" checksum="97D59AD23812EBFC" modified="2010-04-20" version="1">MATTTTKKTLTPIQWAAAIVGAVFLLAGIAGFVPGLTTEYHNLETAGHESHALLLGLFQVSILHNVVHLLFGVVGLAVATTNVGSSYWFLVAGGAIYVVLWVYGMLLDPDSTANFVPLNAADNWLHLLLGVGMVGLGLFLRGKSKTDVKKMVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXM9</accession>
    <name>D3PXM9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Autoinducer 2-binding protein LsrB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_3702</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018930.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3702"/>
    <dbReference type="EnsemblBacteria" id="ADD43359">
        <property type="protein sequence ID" value="ADD43359"/>
        <property type="gene ID" value="Snas_3702"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3702"/>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_3_0_11"/>
    <dbReference type="OMA" id="KQVNNPY"/>
    <dbReference type="OrthoDB" id="669710at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015762">
        <property type="term" value="P:rhamnose transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030159">
        <property type="entry name" value="LsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013459">
        <property type="entry name" value="RhaS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46847:SF4">
        <property type="entry name" value="PTHR46847:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02637">
        <property type="entry name" value="RhaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0574">Periplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048059" description="Autoinducer 2-binding protein LsrB" evidence="7">
        <location>
            <begin position="26"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="8">
        <location>
            <begin position="40"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD43359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="343" mass="36055" checksum="D30C0445096F9D55" modified="2010-04-20" version="1">MALLHSRGRRLATIAGLAVTLTVAAAGCSGGSGDDGGYDIAFLPKNLGNPYFEASDKAAEKAVKGFGGSFKEVGPSEATADGQVTYINTLTQQSVGAIVLSANDTSALCDALDEARDAGIKVVTFDSDVDKECRDVYVSASSPKLIARNQIDLIADQVGGKGEIAILSATANATNQNAWIDEMKPYLKSEYPDMKLVDVVYGDDDDQTSYDKTEALLSSHPDLAGIVSPTTVGVAAAARYLSTSEFKGKVALTGLGTPNDMREYVDNGTVTSFALWNPEDLGILASYTAKALLDEDITGKKGDTFSAKGLSSDTTKFTVGSDGVITLGEPFVFDKDNIDDFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY02</accession>
    <name>D3PY02_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bile acid:sodium symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020902.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5701"/>
    <dbReference type="EnsemblBacteria" id="ADD45331">
        <property type="protein sequence ID" value="ADD45331"/>
        <property type="gene ID" value="Snas_5701"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5701"/>
    <dbReference type="eggNOG" id="COG0385">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034788_1_1_11"/>
    <dbReference type="OMA" id="QFTIMPL"/>
    <dbReference type="OrthoDB" id="1493959at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004710">
        <property type="entry name" value="Bilac:Na_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="PTHR10361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="319" mass="32900" checksum="385AC5E669F800B9" modified="2010-04-20" version="1">MSALQRIGAFTGRWFPVIVLAAGAVALAAPSAFAFAAPAVPWLLAVIMLGMGMTLRPADFAIIGKRPIPVLLGVAAQYVVMPLLGYGLAVAFDLPTMLAVGMVLVGAAPGGTASNVMVFLARGDTALSVAMTTLSTLLAPLLTPVLVWLLAGRFLPVDVGDLFFSIVQVVLVPIVIGLLLRRFVPKVVDRCEDALPLVSVAGITVVVMVVVAGSADILLKVGALVVLAVIVHNVCGLALGYGIARVFGMPVTGRRAISIEVGMQNSALAAALAMAHFNPAAALPAVVFSVWHNVSGSLLAGYWSRRTSPDTEPAPEPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY12</accession>
    <name>D3PY12_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5711</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020912.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5711"/>
    <dbReference type="EnsemblBacteria" id="ADD45341">
        <property type="protein sequence ID" value="ADD45341"/>
        <property type="gene ID" value="Snas_5711"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5711"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_465331_0_0_11"/>
    <dbReference type="OMA" id="DHNWRDS"/>
    <dbReference type="OrthoDB" id="343234at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048688" evidence="2">
        <location>
            <begin position="33"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="558" mass="61182" checksum="52FA50DA2DAA59F0" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY50</accession>
    <name>D3PY50_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5749</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020950.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5749"/>
    <dbReference type="EnsemblBacteria" id="ADD45379">
        <property type="protein sequence ID" value="ADD45379"/>
        <property type="gene ID" value="Snas_5749"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5749"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115860_0_0_11"/>
    <dbReference type="OMA" id="FLCMDLG"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="193" mass="19985" checksum="4FA2A87CCF3B03B6" modified="2010-04-20" version="1">MPRPRATTDADILAATGRAIGAHGPAKLTLAHIGAEAGISPATLSQRFGSKRGLLLAFAADAAATASAPFHRARAANDSPLAALHAVAAEFAGHMSTPEVMANHLGMLQLDLSDPEFRVHAAAHTRAVEAALRELITDAVAAGELSPGTDAPRLARAVNITIDGSLLRWALTSDGDPAALLHDDLDHLLRRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY54</accession>
    <name>D3PY54_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5753</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5753"/>
    <dbReference type="EnsemblBacteria" id="ADD45383">
        <property type="protein sequence ID" value="ADD45383"/>
        <property type="gene ID" value="Snas_5753"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5753"/>
    <dbReference type="eggNOG" id="COG4209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_1_11"/>
    <dbReference type="OMA" id="DKWLYLL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="99"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="329" mass="36319" checksum="1A8528CDA22FD66D" modified="2010-04-20" version="1">MAPTPVATPPRSAPPKTATVRTVKARRAPLRDRLRRDWLLLLLLVPGVGYFLVFHYGALFGNLIAFKDYVPFYGVWASEWIGVQKFTDLVGNTEFWQATWNTVSISFLQLLFYFPAPLGLALLLHSLTRDSIRRFVQSVVYLPHFISWVIVVALFQQVLGDVGVLNGLLADGGLSTVDIIGNPDAYKPLVIAQVIWKECGWGTIIFLAALAGVNEQLYEAAAIDGAGWWRRTWHVTLPAIRPVIILLLILRLGDILTVGFEQFFLQRNAVGPEAGEVLDTFVYYMGIQNGDFSLGAAAGLMKGVVGLVLVYTANKIAHRLGESGVYKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYJ2</accession>
    <name>D3PYJ2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1863</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017130.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1863"/>
    <dbReference type="EnsemblBacteria" id="ADD41559">
        <property type="protein sequence ID" value="ADD41559"/>
        <property type="gene ID" value="Snas_1863"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1863"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="PIHAGAN"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="9"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="360"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="363"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="392"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="450" mass="46495" checksum="67B7FBC56B5C1BE2" modified="2010-04-20" version="1">MNQVLADRYRIDTELARGAAGVVHRAHDRITGEDVAIKILHADAASEPAVATAFLDEAEVLTELNHPGIVRPRDLIVNGTLMALVMDLVDGVDLRRVVIDGGPLPSRRAAVVVSEVAEALAAVHAKGIIHGDVKPGNILIPSDGGSVRLVDFGVARRIASPDAPTHATPDYTAPEIVDGGHSTDKSDVYGLGLVLYEALCGVSPYRGGSIDDVLDRHRAMIPLRPETVVAELWSIIESCLALDPADRPGAQAIPSMLRATMPLLSDEAADAVTPRLAPRPPVTPPEPMPFLAPTPVTPAAGDAPPTSVVPASPVAILGESSETKGRNKSKLLIAAAAGIVVIAAAGVLGFAWLAGATVDDSKPYEPQADEQTSEDPDSKDTKDKKNNDDSTPSEEPSSTDEPSSSPTGESGGENGTGGDSGEENGNGGSEGDFPGEGPIGSTFPDKPGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYS8</accession>
    <name>D3PYS8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3855</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019082.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3855"/>
    <dbReference type="EnsemblBacteria" id="ADD43511">
        <property type="protein sequence ID" value="ADD43511"/>
        <property type="gene ID" value="Snas_3855"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3855"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="WARINRH"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="17"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="103"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="172" mass="19805" checksum="69CAD8C0EAC3F279" modified="2010-04-20" version="1">MRAEQEAEFREYVAARAGQLRRCAYLVCGDWHRAEDAVQIAFVKLYGAWNRARRSGLDAYARRIVLNSVIDDHRRAWFRRERSSERLPERPLGDHSQASADRLTIMNALALLPVRQRAVIVLRYWDDQPVEQTALIMRCSTGTVKSQTARGLRTLRGLLTESIHERIEGITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYT1</accession>
    <name>D3PYT1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3858</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019085.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3858"/>
    <dbReference type="EnsemblBacteria" id="ADD43514">
        <property type="protein sequence ID" value="ADD43514"/>
        <property type="gene ID" value="Snas_3858"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3858"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_0_11"/>
    <dbReference type="OMA" id="QEAFTWW"/>
    <dbReference type="OrthoDB" id="1275789at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="252" mass="26917" checksum="9FFFC1A45C025C3E" modified="2010-04-20" version="1">MTDSATIKTDIDGPVARITLMRPQVRNAQTPDMWQELREAGRNLPGDIRCVIVAGQGPAFSAGLDFEILSGPLPRELAEMSDDDAEARLWSFQEAFDWLRRPDLVSIAAVQGHAIGAGLQLALACDLRVIAADARLRVGEPGLGLVPDLGGTKRLVSLVGYSRAMELCLTGRTVTAEESMALGLATVTVPVEELDDAAEDLALAVLSVPRDAAIETKALLLQAAGNDDSTQLAAERAAQLRLLRSRVPVEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYV8</accession>
    <name>D3PYV8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KDPG and KHG aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019112.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3886"/>
    <dbReference type="EnsemblBacteria" id="ADD43541">
        <property type="protein sequence ID" value="ADD43541"/>
        <property type="gene ID" value="Snas_3886"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3886"/>
    <dbReference type="eggNOG" id="COG0800">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077795_2_1_11"/>
    <dbReference type="OMA" id="DMGSASY"/>
    <dbReference type="OrthoDB" id="1497385at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00452">
        <property type="entry name" value="KDPG_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="PTHR30246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="201" mass="19972" checksum="634B209D1049F468" modified="2010-04-20" version="1">MSFEELFGDDRVMVILRGLPPEDTVALAHTAWDAGVNLLEVPIGEPGQEKSLAAAVAAGAERGLDVGAGTVVSRAHVDAAAAAGAAYTVAPGLDPDVAAASFDAGMPHLPGVATASEIQRALAAGCDWVKAFPAAALGTSWFRAMHGPFPHLNIVATGGVSVASAPDFLAAGASVAALGSALADPQAVAGLARLVADTTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYX0</accession>
    <name>D3PYX0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">L-carnitine dehydratase/bile acid-inducible protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019124.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3898"/>
    <dbReference type="EnsemblBacteria" id="ADD43553">
        <property type="protein sequence ID" value="ADD43553"/>
        <property type="gene ID" value="Snas_3898"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3898"/>
    <dbReference type="eggNOG" id="COG1804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033975_5_0_11"/>
    <dbReference type="OMA" id="FHDSPFY"/>
    <dbReference type="OrthoDB" id="969868at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="SSF89796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="380" mass="39627" checksum="38E4D6AA51A2266A" modified="2010-04-20" version="1">MGPLSGIRVIELASLAPAPFTATVLSDLGAEVLRLDRAETVPSTTGSPPPEPLGRGRRSVAVDLKRPGGASLVLDLVGRTDVLLEGFRPGVCERLGIGPDACLARNPRLVYGRLTGWGQTGPLAQRAGHDINYLALSGALYPIGPADGPPTPPINYVADFGGGGMLLAVGVLAALFERERSGAGQVIDAAMTEGAGLLSSLLHGLKARGMWSDERGGNPLDGTAPFYGTYACADGGFVAVGALEPQFYAELVKGLELIDPPTQYDQSGWPEARRRFADAFASRTRDEWAAVFEGTDACVTPVLTLDEAPDHPHNRARASFTEVAGLRQPAPAPRLSRTPGAVAGPAPQPGEHTRAALTDWGISAEDLAGLFATGVLSELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ14</accession>
    <name>D3PZ14_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">L-ectoine synthase</fullName>
            <ecNumber evidence="4 7">4.2.1.108</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">N-acetyldiaminobutyrate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ectC</name>
        <name evidence="8" type="ordered locus">Snas_5813</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(2S)-4-acetamido-2-aminobutanoate = H2O + L-ectoine</text>
            <dbReference type="Rhea" id="RHEA:17281"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58515"/>
            <dbReference type="ChEBI" id="CHEBI:58929"/>
            <dbReference type="EC" id="4.2.1.108"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amine and polyamine biosynthesis; ectoine biosynthesis; L-ectoine from L-aspartate 4-semialdehyde: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the ectoine synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.108" evidence="4 7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021014.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5813"/>
    <dbReference type="EnsemblBacteria" id="ADD45443">
        <property type="protein sequence ID" value="ADD45443"/>
        <property type="gene ID" value="Snas_5813"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5813"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_154525_0_0_11"/>
    <dbReference type="OMA" id="CVFNPPI"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="UniPathway" id="UPA00067">
        <property type="reaction ID" value="UER00123"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033990">
        <property type="term" value="F:ectoine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019491">
        <property type="term" value="P:ectoine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06978">
        <property type="entry name" value="cupin_EctC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01255">
        <property type="entry name" value="Ectoine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010462">
        <property type="entry name" value="Ectoine_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39289">
        <property type="entry name" value="PTHR39289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06339">
        <property type="entry name" value="Ectoine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="139" mass="15711" checksum="9A9A1D32F5BE91BD" modified="2010-04-20" version="1">MIVRRLNEIVGTERDVLGHDRDVAEGTWRSRRLILANDRVGFSMHDTVLYAGTETSMWYANHVEAVYVIEGNGELIDNETGQKHELSPGTMYLLDGHERHTLRAHTDVRTVCVFNPPVTGKEVHDANGVYPLLTEDDPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ28</accession>
    <name>D3PZ28_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Triacylglycerol lipase</fullName>
            <ecNumber evidence="3">3.1.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021028.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5827"/>
    <dbReference type="EnsemblBacteria" id="ADD45457">
        <property type="protein sequence ID" value="ADD45457"/>
        <property type="gene ID" value="Snas_5827"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5827"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038449_3_0_11"/>
    <dbReference type="OMA" id="NIGESYH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triglyceride lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01823">
        <property type="entry name" value="SEST_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037460">
        <property type="entry name" value="SEST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981">
        <property type="entry name" value="PTHR37981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048114" evidence="1">
        <location>
            <begin position="38"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="45"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="266" mass="27636" checksum="614D8BB9330F2D86" modified="2010-04-20" version="1">MSSKSSPSRRLIARLSALALTAAVALGTTLVASPATAAPLVFAGLGDSYASGVGAGDYIGSDDCYRSSHAYPKQVADAYGEYLYFNACSGAKVQDVIDNQIGNISIAEHITIGVGGNDAGFSRVLGACAGTDTALCLSQVEAANTFIRDELPARLDTLYTKVGERTTYADVAVVGNPRLFNGTTCAGTLAITPEEQEALNGTADLLATTTKGVAADHGYRFVDPRDAFASHAICSADPWLLGWTGSQLESFHPNVAGQNAYTDLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZA6</accession>
    <name>D3PZA6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1884</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017151.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1884"/>
    <dbReference type="EnsemblBacteria" id="ADD41580">
        <property type="protein sequence ID" value="ADD41580"/>
        <property type="gene ID" value="Snas_1884"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1884"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="RIAHEMH"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="3">
        <location>
            <begin position="181"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="383" mass="41192" checksum="ED9647EAB96C11C0" modified="2010-04-20" version="1">MTWETATRWWGRARPFVFAAVVFVVGLIPVNDERTPDWLALPTVWRAAIPAALALAAAWLLPRRWPMVALAVVVSPFDTLIAGTCLIVASYVIATGYRGVVELVLSLVAVLCAPLIPTLASAPSVDDLMGWLGGTALFVWLPLTVGLWVRTRRVTLESLRDKASRLEREQAAVAARARAEERGRIAHEMHDVVAHRVSLMVMHAGALEVNAPDAAVAESAELIRATGSEALAQLRDVLGVLRYGETARTTPQPTLADLDTLLAESRRAGVDATATSTGEAQPLSTLVDQTAYRVIRESLTNVHKHAGAVACVVTLDHQPERLLVTVRNDPPRRPPRLPGSGTGLIGLRERLTLLGGELSTRAEPDGGFRLTASIPLRTETAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZF4</accession>
    <name>D3PZF4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017199.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1932"/>
    <dbReference type="EnsemblBacteria" id="ADD41628">
        <property type="protein sequence ID" value="ADD41628"/>
        <property type="gene ID" value="Snas_1932"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1932"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_3_11"/>
    <dbReference type="OMA" id="PRWHRGL"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="18"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="390" mass="40593" checksum="02782C768ABFD929" modified="2010-04-20" version="1">MTRRQTPGVPQLLRVLNDRAALNLLFTNGPQTRAQLAQATSLSKVTASQMVERLESRGLIKAVGTRPGNRGPNAQVYAVVSTYAYVAGVNVGPHSVTVDIADLTGEVVGRVELETRDADDPVAVVHRAVTAASANAKIQLEDVDRVVLATPGIVNPDSNDIDFSWDLPAWHRGLHEALEKDLRRPVVIENDVNLAAVAEHRDGAARGVDDFVYVWFSRGLGVGVVLGGKLHRGARGGAGEIGYLAVPGGSLPEESVTRRAKGSFQKLVGGDAVQELGTEHGFTQDTPEAMVAAALSAGDAGEKFLDELADRMALGVAGVCSVLDPALVVLGGEVGYAGGAGLADRVGAAIQDIAPLSSQVVAGTVSSGPILRGALRVGLDAVREGLFSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZM7</accession>
    <name>D3PZM7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3909"/>
    <dbReference type="EnsemblBacteria" id="ADD43564">
        <property type="protein sequence ID" value="ADD43564"/>
        <property type="gene ID" value="Snas_3909"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3909"/>
    <dbReference type="eggNOG" id="ENOG503469M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1618025_0_0_11"/>
    <dbReference type="OMA" id="SHLWRSH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="164" mass="18329" checksum="99432E925501A63E" modified="2010-04-20" version="1">MSGMLPVRFRPTSRQILGRAMLVGLLTAVVVAIPVVVLWARGELVWWEVLLLPVGCVAGALLAAPLLRRGGIDVDESGVHPVIPGPARREFAPWHHINDIRAERRGARTVPVIYLDGDRSWRLRVPYDGVLLGGDPHFDEKLCTIRNMWETHHTWQRDPVAGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZN2</accession>
    <name>D3PZN2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid permease-associated region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3914</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019140.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3914"/>
    <dbReference type="EnsemblBacteria" id="ADD43569">
        <property type="protein sequence ID" value="ADD43569"/>
        <property type="gene ID" value="Snas_3914"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3914"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_15_12_11"/>
    <dbReference type="OMA" id="HKAFGIH"/>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="472" mass="49793" checksum="77CB0D69AC276D46" modified="2010-04-20" version="1">MANSPVTDVPAEDIPPTELKRAIGPKLLLLFIVGDILGTGIYALTGQVANKVGGALWIPFAVAFIAAFLTAFSYLELVGKYPRAAGAALYTQKAFGIHFLTFMVAFTVMSSGMTSAGSAARAMAADFFPQVFTWLPGTDSSIIILAATMLVIFGVVNLRGVSESVWANVIFTLIELTGLAIIIVVSIAAVMAGGDNIDAGRLLEINTGDSSAFFAVVAGTSLAFFAMVGFEDSVNMAEETTNPRIFPKAMLTGMGIAAVIYISVAVLSSWVAPTDVLIGDDEANPGAGALLRVLEIGAPDFPLWVFGLISIFAVSNSALINMLMASRLVYGMSREKVIPKVFGRVAPTRRTPWVAIIFTSAIAIGLTSYANVGDLGGTTALLLLAVFTIVNIAVLVLRRKPVEHKHFKAPTIVPIIGALISAFLVGPWSGRDPKQYQIAGILLAIGIVLWAITFAFQKMGAKRDDSSPKADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q024</accession>
    <name>D3Q024_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021124.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5925"/>
    <dbReference type="EnsemblBacteria" id="ADD45553">
        <property type="protein sequence ID" value="ADD45553"/>
        <property type="gene ID" value="Snas_5925"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5925"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_27_0_11"/>
    <dbReference type="OMA" id="TEGERYP"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="18"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="211" mass="23678" checksum="4271B7226717059A" modified="2010-04-20" version="1">MANPTSTWQTPSRRRQTEAKRTSILDAAEELFVSSGYELTSVDAIAARASVSKRTVYDHFGDKRSLYRSVLGRVDDALLVTIRAAVQQELTDQRDLREALLAFVQRLTTDVIPSSTYATFRHLIAKTAAAPQLPERSHEEPEKVLEERFAQLAADGRLTISDPRRAVQHFFALTMRLVLDETDQDPTGTVAKTEIEAIITDGVDVFLRAYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q062</accession>
    <name>D3Q062_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplK</name>
        <name evidence="11" type="ordered locus">Snas_5964</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6 8">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021162.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5964"/>
    <dbReference type="EnsemblBacteria" id="ADD45591">
        <property type="protein sequence ID" value="ADD45591"/>
        <property type="gene ID" value="Snas_5964"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5964"/>
    <dbReference type="eggNOG" id="COG0080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074237_2_1_11"/>
    <dbReference type="OMA" id="CKQFNAK"/>
    <dbReference type="OrthoDB" id="1702697at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_L11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_L11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0488">Methylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L11_N" evidence="10">
        <location>
            <begin position="12"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="9">
        <location>
            <begin position="73"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD45591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="15067" checksum="E024FB2A39912DF8" modified="2010-04-20" version="1">MAPKKKLSVVFKLELTAGQATPAPPVGPALGQHGVNIMEFCKAYNAATEGQRGEIVPAEISVYEDRSFTFVLKTPPAAKLLLKAAGVDKGSGEPHRLKVGKVTAAQVREISEKKMPDLNANDLDAADKIIAGTARSMGITVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0R2</accession>
    <name>D3Q0R2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2104</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017369.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2104"/>
    <dbReference type="EnsemblBacteria" id="ADD41798">
        <property type="protein sequence ID" value="ADD41798"/>
        <property type="gene ID" value="Snas_2104"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2104"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_11"/>
    <dbReference type="OMA" id="EMGSDDY"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="225" mass="24731" checksum="8900BEB5C5DF04D4" modified="2010-04-20" version="1">MRLLIVEDEKRLADVVAAGLTAEGYGVDVANDGTTGFSMARQNPYDVIILDIMLPGMNGYQVCRKLREAEVRTPILMLTAKDGEHDEADGLDLGADDYLTKPFSFVVLQARIRALLRRSVSTAPTVWEFGDLVIDPAAKTVRRGEADISLTAKEFAVLEYLASRAGEVVSKTEVLEHVWDFAYDGDVNIVEVYISYLRRKLDAPFGRQAITTLRGAGYRLAADGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0S4</accession>
    <name>D3Q0S4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP-dependent DNA helicase RecG</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2116</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017381.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2116"/>
    <dbReference type="EnsemblBacteria" id="ADD41810">
        <property type="protein sequence ID" value="ADD41810"/>
        <property type="gene ID" value="Snas_2116"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2116"/>
    <dbReference type="eggNOG" id="COG1200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005122_7_1_11"/>
    <dbReference type="OMA" id="DNGFQAC"/>
    <dbReference type="OrthoDB" id="234717at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045562">
        <property type="entry name" value="RecG_dom3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033454">
        <property type="entry name" value="RecG_wedge"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19833">
        <property type="entry name" value="RecG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17191">
        <property type="entry name" value="RecG_wedge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="283"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="482"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="718" mass="77590" checksum="5B70C7CEAB50270F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0X5</accession>
    <name>D3Q0X5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4073</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019296.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4073"/>
    <dbReference type="EnsemblBacteria" id="ADD43725">
        <property type="protein sequence ID" value="ADD43725"/>
        <property type="gene ID" value="Snas_4073"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4073"/>
    <dbReference type="eggNOG" id="COG0637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_13_1_11"/>
    <dbReference type="OMA" id="YCICSNA"/>
    <dbReference type="OrthoDB" id="1167152at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="219" mass="23262" checksum="F4EBD618D9A901FD" modified="2010-04-20" version="1">MGYRGVVFDMDGVIVESEHLWEESWTASCARRGVDWSGEDTTSVQGMSAPEWARYVAEKIGDTSLADVVQAECVDHVVAAVHDGQAPLLDGARELVVKIADLTPIAMASSAARPVIDAVLDRNELADRFGATVSSEEVARGKPSPDVYAEAAQRVQIEPSHGIAVEDSSNGIRSAHAAGLHVVAIPNRSYPPAADALALAEHVADDHHDALDHILSLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0X9</accession>
    <name>D3Q0X9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4077</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019300.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4077"/>
    <dbReference type="EnsemblBacteria" id="ADD43729">
        <property type="protein sequence ID" value="ADD43729"/>
        <property type="gene ID" value="Snas_4077"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4077"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_3_11"/>
    <dbReference type="OMA" id="GASWFYM"/>
    <dbReference type="OrthoDB" id="1619224at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="175"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="91"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="317" mass="35249" checksum="02E2ACD49B52D7AA" modified="2010-04-20" version="1">MSATTSTERQRPSDETPPRPAAPTVSRRRRARRPYLLAVPAVLLCVGILYPFFVGVGYTVYNFSASNPQPDFVGLKNFTDVFSSSQFWDSVTVTGTFAVVATAVETVLGVGVALLLYRSSLLGRIFERVLIVPLMVAPILAAIMWKLLLLPEVGWIRPIVEAFGFTGYSGTDDPFWAFFWSIVVDAWIYTPFVAIIALAGLRSLPNSPFEAAAVDGASWWLTFRRLTLPMLWPYVLVAVIFRLMDSLKMFDIIFGLTNGGPGGATTTIQINAYLESISYARYSKGITYMFVLWAVVYVISMFLVRYLRKVQTRSAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q134</accession>
    <name>D3Q134_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">6-deoxyerythronolide-B synthase</fullName>
            <ecNumber evidence="8">2.3.1.94</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_4133</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="2.3.1.94" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019355.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4133"/>
    <dbReference type="EnsemblBacteria" id="ADD43784">
        <property type="protein sequence ID" value="ADD43784"/>
        <property type="gene ID" value="Snas_4133"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4133"/>
    <dbReference type="eggNOG" id="COG3319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_16_5_11"/>
    <dbReference type="OMA" id="FDAGYWA"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047879">
        <property type="term" value="F:erythronolide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033068">
        <property type="term" value="P:macrolide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020802">
        <property type="entry name" value="PKS_thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015083">
        <property type="entry name" value="Polyketide_synth_docking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08990">
        <property type="entry name" value="Docking"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00824">
        <property type="entry name" value="PKS_TE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="2 6" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="940"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="6">
        <location>
            <position position="975"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1305" mass="139502" checksum="577D9A86555478C4" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1E0</accession>
    <name>D3Q1E0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ErfK/YbiS/YcfS/YnhG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6096</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021291.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6096"/>
    <dbReference type="EnsemblBacteria" id="ADD45720">
        <property type="protein sequence ID" value="ADD45720"/>
        <property type="gene ID" value="Snas_6096"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6096"/>
    <dbReference type="eggNOG" id="COG1376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056729_1_0_11"/>
    <dbReference type="OrthoDB" id="975147at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049639" evidence="3">
        <location>
            <begin position="41"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="4">
        <location>
            <begin position="138"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="254" mass="27686" checksum="C0891BB4BB3A1F76" modified="2010-04-20" version="1">MKGEAVRYLRASLTAAAVLVALAAAGGGTYAFLTGGSAEAAAPDPTPSTVTPTKDHDCGKVGEFQEEVEKSLESLAEYGSVFVDGEQSQEDCDAIEAFQKRFGIKPAKGRADELTRDVAKRIAEQSFDECPTAEHGTTVCVDLTNQTLWVVEDGERIFGPTVVRTGMAGHASTTGTHTINHRADREWSEPYEQWLPYWQHYYAGEGLHETTSYLHDPSLGSHGCTNLLRQDAKKLYEMLDYGDTVEVFGKRSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1G0</accession>
    <name>D3Q1G0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021311.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6116"/>
    <dbReference type="EnsemblBacteria" id="ADD45740">
        <property type="protein sequence ID" value="ADD45740"/>
        <property type="gene ID" value="Snas_6116"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6116"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_711538_0_0_11"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="388" mass="41002" checksum="BC84A083BE228949" modified="2010-04-20" version="1">MTTKQLKDLLTDMADEVQPTRVHERAVAQSKRIGRRNAILASITALLLTGSGLFGFSVLAHGMGNGGTEHQVADGELPTSDVNKLSGTYYQVSDPDGEPESVVSWQAGGDEVAEPLTAIDTEDQYYATGNVSPNGEYFSYMTSPSNDGGDPEVTDRIFVATFADNATGEVAQYSAAEDLCAEPVWAPDSKRLFVDRGSAGDGDRTGFVDVETSEFTSFPVENPCDAQVATNADGEDLVFSTEASGDSVEVYATNGSGERTATGAAKVMMESGRYITELVAVSPDGRFLCVSTESEPGSYTEDMSAGRYGYCDAIIDTGAKEEIEVSDNNGVLPTGSPSVFAIPGRLLLEGDDGKGNGIHLLYDYDGKLIDEASSPMGEESLPSAFVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1H5</accession>
    <name>D3Q1H5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell division protein CrgA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">crgA</name>
        <name evidence="4" type="ordered locus">Snas_6132</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in cell division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CrgA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021326.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6132"/>
    <dbReference type="EnsemblBacteria" id="ADD45755">
        <property type="protein sequence ID" value="ADD45755"/>
        <property type="gene ID" value="Snas_6132"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6132"/>
    <dbReference type="eggNOG" id="ENOG5032F8D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149126_1_0_11"/>
    <dbReference type="OMA" id="WNIVVGF"/>
    <dbReference type="OrthoDB" id="2085550at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00631">
        <property type="entry name" value="CrgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009619">
        <property type="entry name" value="CrgA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06781">
        <property type="entry name" value="CrgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="87" mass="9748" checksum="B0C6C76105CD40EC" modified="2010-04-20" version="1">MPKSRVRKKKVYTAPAELRPKTPESTHQPSPTWVPVLAVILIVLGIGWLVTFYLTEGSFPVAPWGYWNLAVGFASLVASLLVLSRWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1I5</accession>
    <name>D3Q1I5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Abhydrolase_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015404.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0112"/>
    <dbReference type="ESTHER" id="stanl-d3q1i5">
        <property type="family name" value="Est9X"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD39833">
        <property type="protein sequence ID" value="ADD39833"/>
        <property type="gene ID" value="Snas_0112"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0112"/>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_10_1_11"/>
    <dbReference type="OMA" id="GGWPTTF"/>
    <dbReference type="OrthoDB" id="1470522at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="1">
        <location>
            <begin position="41"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="270" mass="29205" checksum="792A565F8ED26CE0" modified="2010-04-20" version="1">MADPREVLTRPAEPGITIAYGDEPDQVVELFQPKGEPKATVVAIHGGFWREAFDRTHLRPFCHGLTAAGFAVVSLEYRRSGGAGGWPQTFEDIEAALELLDDELTEHDVDPDNVILTGHSAGGHLALLAADLPWAEPDLTFTPLLQPGGVMVERGQSRLRGVVALAPVSDLPRCYVEHLGDGAAAALMGGGPADFPAEYAEADPMRRELGVPVMVVHGEADDRVPVQMSRDYVVRRKAELRELPGIGHFEVIDPQSTIWPEVLDALNSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1S3</accession>
    <name>D3Q1S3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha-L-arabinofuranosidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0202</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 51 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015492.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0202"/>
    <dbReference type="CAZy" id="GH51">
        <property type="family name" value="Glycoside Hydrolase Family 51"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD39921">
        <property type="protein sequence ID" value="ADD39921"/>
        <property type="gene ID" value="Snas_0202"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0202"/>
    <dbReference type="eggNOG" id="COG3534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017810_1_1_11"/>
    <dbReference type="OMA" id="EYCNGEA"/>
    <dbReference type="OrthoDB" id="620389at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046373">
        <property type="term" value="P:L-arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010720">
        <property type="entry name" value="Alpha-L-AF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06964">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00813">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-L-AF_C" evidence="3">
        <location>
            <begin position="294"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD39921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="505" mass="55992" checksum="EA914872580F276B" modified="2010-04-20" version="1">MDNRHKASVVLDPAFAVAPVDRRLFGSFVEHMGRCVYGGIYDPGHPSADEHGLRTDVIDLVRELGVSVVRYPGGNFVSSYRWEDGIGPVADRPRRLNLAWRCLETNEFGLGEFMTWARLAVVEPMMTVNLGTRGVAEACDMIEYCNHPGGTALSDLRRKHGSADPYDIKLWCLGNEMDGPWQVGQKTAAEYGRIAAETGKAMRIVDPSIELVAAGSSNSQMPTFGDWEATLLEHAYDQVDYLSLHHYFDPANQDRDSFLASGTVMDRFIDDVVSTCDHIGAKRRSRKKIKLSFDEWNVWYQSRFTEPGDREWIESPPLIEDDYDATDAVVVGDLLITLLRHADRVSIANQAQLVNVIAPIRTAPDGPAWRQSIFHPFALTSRLARGTVLRTETAGPRHETPRHGEVPTLSTTATHDAATGQTVLFAVNRAEHPVELAVDARALSGVRLAEHLTIAEDDPTAINTPADPDRVGPRRLPPSVMDNGRCLVRLPALSWNALRLSEEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1X6</accession>
    <name>D3Q1X6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2149</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2149"/>
    <dbReference type="EnsemblBacteria" id="ADD41843">
        <property type="protein sequence ID" value="ADD41843"/>
        <property type="gene ID" value="Snas_2149"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2149"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="CEGRTIR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03793">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00740">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51178">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="10"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="6">
        <location>
            <begin position="405"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="291"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="357"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="379"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="427"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="480" mass="50837" checksum="EC479404516C0A99" modified="2010-04-20" version="1">MRGSMVAGRYRLDDRIASGGQGEVWRGFDTRLERPVAIKLLHSGLSGNERFRTRFHQEAKAVAALQAPGIVGLYDYGEDQTADGISSYLVMELVNGPSLANLIRERGRLDPREAMRIVAETADALESAHRVGLVHRDIKPANILITSDGHPKIVDFGIARAKGEAGLTETGMVMGTVAYASPEQLCDNNLTGSSDIYSLGIVAHECLSGRQPFHSDSPAAAIQAQLNQPPPPLPGDIPKPVADVVRKALAKDPRDRWASASEFAQACRDAGSGGGTTVLLASAAAATQVMPQNTQVMPRNTGQMGRAVPPRRPEPPMPPPRDPEPEEKKGKAVPILATLAIVAVLAALLVLWSPWSRGEPEPNADNTTSAKKDTATSDEETTEDETTEDEPTSEDEPTSDTPTTGPELVAVPDSTGKLAGQYQDELTSAGLRPSMTEDPTGQGQACSITSVDPEPGTEVAQDSVVTVTFIGTAADCDVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q200</accession>
    <name>D3Q200_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PqqA peptide cyclase</fullName>
            <ecNumber evidence="7">1.21.98.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Coenzyme PQQ synthesis protein E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pqqE</name>
        <name evidence="9" type="ordered locus">Snas_2175</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[PQQ precursor protein] + S-adenosyl-L-methionine = 5'-deoxyadenosine + E-Y cross-linked-[PQQ precursor protein] + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:56836"/>
            <dbReference type="Rhea" id="RHEA-COMP:14800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:141026"/>
            <dbReference type="ChEBI" id="CHEBI:141027"/>
            <dbReference type="EC" id="1.21.98.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with PqqD. The interaction is necessary for activity of PqqE.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the radical SAM superfamily. PqqE family.</text>
    </comment>
    <dbReference type="EC" id="1.21.98.4" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017438.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2175"/>
    <dbReference type="EnsemblBacteria" id="ADD41867">
        <property type="protein sequence ID" value="ADD41867"/>
        <property type="gene ID" value="Snas_2175"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2175"/>
    <dbReference type="eggNOG" id="COG0535">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009273_4_7_11"/>
    <dbReference type="OMA" id="QLMPTRE"/>
    <dbReference type="OrthoDB" id="1172757at2"/>
    <dbReference type="UniPathway" id="UPA00539"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009975">
        <property type="term" value="F:cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018189">
        <property type="term" value="P:pyrroloquinoline quinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00660">
        <property type="entry name" value="PqqE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023885">
        <property type="entry name" value="4Fe4S-binding_SPASM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011843">
        <property type="entry name" value="PQQ_synth_PqqE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017200">
        <property type="entry name" value="PqqE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13186">
        <property type="entry name" value="SPASM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037420">
        <property type="entry name" value="PQQ_syn_pqqE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00280">
        <property type="entry name" value="coenzyme_PQQ_synthesis_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02109">
        <property type="entry name" value="PQQ_syn_pqqE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04085">
        <property type="entry name" value="rSAM_more_4Fe4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 7" id="KW-0884">PQQ biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD41867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="350" mass="38350" checksum="0431D9E9DF800275" modified="2010-04-20" version="1">MLAELTHRCPLHCPYCSNPLELLGRDSELSTKQWISVLDQARELGVLQVHFSGGEPLARKDLPELVAHASGLGQYVNLVTSGLGLTEERLSDLAGRGLNHVQLSVQDAEPESANLLAGTRAHAHKITAARLVNAAGLPLTVNVVLHRGNIDRIGAIIDFAEELGAQRLELANTQYYGWALRNRDALLPSRAQLDAAALVVREASERLSERLDLIYVLADYYADRPKPCMYGWGSRQFTVAPDGDVLPCPAATAITDLRMDNVTTTALADIWYRSDSFNAFRGQEWMREPCRSCDRREIDFGGCRCQAFLFTGDATSTDPVCGLSPDRHLIDAILEADAVAPAFVMRKAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2A7</accession>
    <name>D3Q2A7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4190"/>
    <dbReference type="EnsemblBacteria" id="ADD43840">
        <property type="protein sequence ID" value="ADD43840"/>
        <property type="gene ID" value="Snas_4190"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4190"/>
    <dbReference type="HOGENOM" id="CLU_1969195_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046151">
        <property type="entry name" value="DUF6153"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19650">
        <property type="entry name" value="DUF6153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="127" mass="13547" checksum="16D9C47F5792DBFA" modified="2010-04-20" version="1">MLWRHPAVRLLLLVLAFGVAGMHTLGHHEGHDTSSSMPGHAVHDEAAASDAVTVTPPTGDMNPSQMCLAVLTAGAALALALIAARTRQRVPASRWRPRLRASRRSSRGPPRSIPVSLLTAQVTVLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2C3</accession>
    <name>D3Q2C3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Recombinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019427.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4207"/>
    <dbReference type="EnsemblBacteria" id="ADD43856">
        <property type="protein sequence ID" value="ADD43856"/>
        <property type="gene ID" value="Snas_4207"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4207"/>
    <dbReference type="eggNOG" id="COG1961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010686_18_18_11"/>
    <dbReference type="OMA" id="GVQRQEK"/>
    <dbReference type="OrthoDB" id="1791095at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011109">
        <property type="entry name" value="DNA_bind_recombinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07508">
        <property type="entry name" value="Recombinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51737">
        <property type="entry name" value="RECOMBINASE_DNA_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Recombinase" evidence="1">
        <location>
            <begin position="158"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="506" mass="56709" checksum="E4310D776852DA71" modified="2010-04-20" version="1">MDKWLALYCRASQDKRGFRESVGDQETWGRAYGAKHFPDLPIKVYIDNDLSAADPTVFRPDFERLREDVRMGHVAQIWSVEQYRLVRQEVEWFSFAAELVEADIIRLHTDRDGVILVDDDVAGIKAVLGGGEVRRQKKRLKSRQDAQAAKGWPAGSRPFGYVHARVKGERTYKVVPEQAEALRWAAGAVVDGWSLTNIAAELTARGFEGAHRKHVKDEHGDDVLDEDGNPVTLPTVINAASVKRMVSNPSVAGWRVHRGQISGRGNWEPILTESLWQQVRTKLSAPRTVRTKAGKQYPVKTTRPGGTARRYELSGGTITCGKCEAPLVGSLKQLRNKKGVRSVPYYFCHPMNGGRSCMGIMAKLTEKYVAARLIKELNKPAVKAALAKDNHAEKRDELTAELVRIDGQRPKLAKAWAADALSDAEWLAAREELDEREAAARAELVALPAPTRRVDPALIADGWDEMTLDERREIISMFVENVTILPARPGLQRFDSDRVKIKWREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2G9</accession>
    <name>D3Q2G9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">6-kinase</fullName>
            <ecNumber evidence="1">2.7.1.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.72" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019473.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4253"/>
    <dbReference type="EnsemblBacteria" id="ADD43902">
        <property type="protein sequence ID" value="ADD43902"/>
        <property type="gene ID" value="Snas_4253"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4253"/>
    <dbReference type="eggNOG" id="COG3570">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061172_2_1_11"/>
    <dbReference type="OMA" id="FDFANIF"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050300">
        <property type="term" value="F:aminoglycoside 6-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006748">
        <property type="entry name" value="NH2Glyco/OHUrea_AB-resist_kin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04655">
        <property type="entry name" value="APH_6_hur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="309" mass="33653" checksum="2426E3704808CED3" modified="2010-04-20" version="1">MRTVPEPVAELIRDIFEEAGERWLAALPDLIADRCDAWDLEITGEAFTGGTHSYVAPVRRADGSSAVLKLTVVDEENRAEATALHHYNGEGAVKLYDYDPGTGAMLMELATPGSPLVQQSYEGVVLEGSPENADKIDIASALYRRLWREPVATPGYPSLPLVRDLVAVWESEIPANADGELPAHLVAQAVDLCRELAKPDGPEGIVNRDTHLGNIVAAQREPWLLIDPKPLLGERAFDAGFFIDKQIHHRPEAGFACQVVARTAEGLGVAPERARAWAFLRAMENAAWAVDDELPERVASEVAIAEALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2H2</accession>
    <name>D3Q2H2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019476.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4256"/>
    <dbReference type="EnsemblBacteria" id="ADD43905">
        <property type="protein sequence ID" value="ADD43905"/>
        <property type="gene ID" value="Snas_4256"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4256"/>
    <dbReference type="HOGENOM" id="CLU_1309483_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="210" mass="23828" checksum="EADAF54218B0A98F" modified="2010-04-20" version="1">MNRSRPAQPHPDASWIGLVARDDRTGFVVGAVMIGAMVVVSALMLGSSGGFAEVSERAESGDGYFAFVLGFCVLLALGLYLRLIRPYLKRRRLGFAVDEHGIWWVDRDEASLLAWPDIAGVGCGFVKVPWTRFSLYSPHQRDLHVEVYLHQMTRARHRHLAELWGVEEEAAHPHMPRIRLRFGEVAPVMMEEFANAVREHDARRWLGLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2L7</accession>
    <name>D3Q2L7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="6">6.3.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">GARS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Glycinamide ribonucleotide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosylglycinamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">purD</name>
        <name evidence="9" type="ordered locus">Snas_6145</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17453"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GARS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6145"/>
    <dbReference type="EnsemblBacteria" id="ADD45768">
        <property type="protein sequence ID" value="ADD45768"/>
        <property type="gene ID" value="Snas_6145"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6145"/>
    <dbReference type="eggNOG" id="COG0151">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027420_3_1_11"/>
    <dbReference type="OMA" id="KATVCKY"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00138">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020559">
        <property type="entry name" value="PRibGlycinamide_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PTHR43472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00184">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="102"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="411" mass="41824" checksum="57886F4F05137065" modified="2010-04-20" version="1">MGTGGREHALAVALAHDSKVETLICAPGNPGMAACGELRDVDMGDPDAIAALAVEVEADLVVVGPEAPLVAGAADAVRAKGIACYGPSAKAAAIEGSKTFAKEIMAAAGVPTAKAHTCHTAAEAEAALDEFGPPYVVKDDALAAGKGVVVTSDRDEALAHAAACDTVVIEEFLDGPEVSLFVVTDGTTAVPLLPAQDFKRVGEDDAGPNTGGMGAYTPLPWAPDDLVDTIMTTVAEPTLAELAKRETPFVGTLYCGLALTSKGPKVIEFNCRFGDPEIQAVLALLDAPLSGLLDAAARGKLAEYPKPQWRDGAAVCVVLASEGYPEKPVTGKPITGADMPGVLHAGTALDADGQLVSSGGRVLNVVAPGATLNQARRRAYALAAGVELPDARIRRDIALAASEDRIVAPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2U2</accession>
    <name>D3Q2U2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021414.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6222"/>
    <dbReference type="EnsemblBacteria" id="ADD45843">
        <property type="protein sequence ID" value="ADD45843"/>
        <property type="gene ID" value="Snas_6222"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6222"/>
    <dbReference type="eggNOG" id="COG3599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1413758_0_0_11"/>
    <dbReference type="OMA" id="GEMMISH"/>
    <dbReference type="OrthoDB" id="2036047at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="116"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="197" mass="22298" checksum="2D6C4901205D207E" modified="2010-04-20" version="1">MTDERRIDAATVNAARFELTPLGRRGYQPEEVHELMSRIAGELERRDATEAALRSESERFRLALREWQSRQSQRQNTMTNKPDTNAVLLLSQAQEQAEGYVAQAQDYCRRLIGQARGQAQQVLEQARRQAEEQAERAAAEYREQAGALHSAQAEEQARRLARVQSFLGAVTAAEEQLREARENLAAEVEHLVQEAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q304</accession>
    <name>D3Q304_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0256"/>
    <dbReference type="EnsemblBacteria" id="ADD39974">
        <property type="protein sequence ID" value="ADD39974"/>
        <property type="gene ID" value="Snas_0256"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0256"/>
    <dbReference type="eggNOG" id="ENOG5032T9P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120565_0_0_11"/>
    <dbReference type="OMA" id="HAFNAGW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="163" mass="17847" checksum="C89DDE099BECB9F8" modified="2010-04-20" version="1">MATTPRHWTLPRILVRVVLFFSLFGPALADLAIPDVAAMHLHNPNWPPHAKFHDAQYLVMAALLAAIGLTMLWRRTGNLRLQFHWAAALASVTWLAMFAALLFPGTGIIDPEFVADNVSILGLNPQLFIALVMLVLLAVAVGVERFGRRIPLAPESNRTPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q306</accession>
    <name>D3Q306_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase, WecB/TagA/CpsF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0258</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0258"/>
    <dbReference type="CAZy" id="GT26">
        <property type="family name" value="Glycosyltransferase Family 26"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD39976">
        <property type="protein sequence ID" value="ADD39976"/>
        <property type="gene ID" value="Snas_0258"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0258"/>
    <dbReference type="eggNOG" id="COG1922">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063203_2_0_11"/>
    <dbReference type="OMA" id="PWRWRRM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06533">
        <property type="entry name" value="Glyco_transf_WecG_TagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004629">
        <property type="entry name" value="WecG_TagA_CpsF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34136">
        <property type="entry name" value="PTHR34136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03808">
        <property type="entry name" value="Glyco_tran_WecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00696">
        <property type="entry name" value="wecG_tagA_cpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="268" mass="30048" checksum="5BEAC051BA45E12B" modified="2010-04-20" version="1">MIDQGKRNVLGVYVDAIDYEAATEKVVDAAREQRPLALTALAVHGVMTGVQDRAHEARLNSFDVVTPDGQPVKWALNLLHKAKLSDRTYGPELTIRVIARMAAEGLPIYLYGSTPEVLDTFRAKLSERFPDLVIAGWEPSKFRANEVGEPEQIAKRITESGARLVLVGLGCPRQEIFAHAMRPLLNMPLMAVGAAFDYHAGNLRKPPEWMQKRGLEWLWRLGLEPKRLWRRYLILNPLYLARLTGQATRVWKAKPATATREGADSFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q404</accession>
    <name>D3Q404_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_6269</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = an N(4)-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:16857"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:13674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:137933"/>
            <dbReference type="EC" id="2.1.1.113"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021460.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6269"/>
    <dbReference type="REBASE" id="24812">
        <property type="entry name" value="M2.SnaDORF6268P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45889">
        <property type="protein sequence ID" value="ADD45889"/>
        <property type="gene ID" value="Snas_6269"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6269"/>
    <dbReference type="eggNOG" id="COG0863">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024927_2_0_11"/>
    <dbReference type="OMA" id="DIIWHKP"/>
    <dbReference type="OrthoDB" id="1487464at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015667">
        <property type="term" value="F:site-specific DNA-methyltransferase (cytosine-N4-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017985">
        <property type="entry name" value="MeTrfase_CN4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00093">
        <property type="entry name" value="N4_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="8">
        <location>
            <begin position="20"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="304"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="333" mass="36478" checksum="932FD613DDFF1D07" modified="2010-04-20" version="1">MTAIVMCADARALPLADESVDLIVTSPPYYGLRSYTNGGRHYDGQIGAEPTPAAYIDALIEATRDWLRVLKPVGSLWVNLGDAYVGGGRGGNLGGHLTGGSHTKTASTPHGTSKYPAKTLLGLPWRYAIRCLDDLGLILRAEVIWSKPNAMPESMTDRVRRSHETWLHFVQHQRYFAAIDGIREPASNYSRPNGAGRQARGGQKPRKMLDTCNPLGRLPGSVWEIATQPLHIPAELNITHHAAFPLEWPRRLIIAWCPPSGTVLDPFGGTGTTALVADVLGRTGISVDASADYCRLARWRTTDPNERARARRAPRPPQQLPGQMPLFELEDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4K4</accession>
    <name>D3Q4K4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0449</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015735.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0449"/>
    <dbReference type="EnsemblBacteria" id="ADD40164">
        <property type="protein sequence ID" value="ADD40164"/>
        <property type="gene ID" value="Snas_0449"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0449"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_686782_0_0_11"/>
    <dbReference type="OMA" id="HIERAEC"/>
    <dbReference type="OrthoDB" id="1382732at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="46"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="405" mass="46027" checksum="7309C2FE930300F6" modified="2010-04-20" version="1">MSEAREAVTESPSDITARVDRYTAVGRFAEAERMVRRALVTYPEHINLLNKLSYTLFSQQRYDEDLEVTDKALALDPNEPVLYWRRSWTLWRLDRRDEAIALARRSLELDPHRELRHAVFEDLGRYYNWEGRHPEAFEITERGLTEFPGDTALLEVAGEALRRQSRYYEADVYYRASLEADPHLGINWYGKALNDMMLGRARASLAGFAHSMVLEPDDDWRAERVRYFMGWPISGYAASFRWTLPLASATALLNPSGTGWPRWFGLVLLALTLAHATSWLYRGGKLSWTALPRLLPLEKLSITLPAVLATLGLAAAVSALLTGSAPLGWLGLAAGVLLWPAFGFDNALNPNESRDSSLPRRTLANTQWWIIDDFTGHPKKQWDRLRHNLKRDKSTPAHISPPSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4M3</accession>
    <name>D3Q4M3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015754.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0468"/>
    <dbReference type="EnsemblBacteria" id="ADD40183">
        <property type="protein sequence ID" value="ADD40183"/>
        <property type="gene ID" value="Snas_0468"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0468"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_13_0_11"/>
    <dbReference type="OMA" id="DMGRWMQ"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="455" mass="48913" checksum="A4D95EA822B460A1" modified="2010-04-20" version="1">MSELDTLADRLGARLTELIAECSTPGAVLGVYSKGEFTERGAGVLNTRTGVEVTPDAVFQIGSITKVWTAALVMRLVEAGELDLDAPVRSYLPKFRLAEESAAASITTRQLLSHTAGFEGDIFTDTGPGDDSLAKFVDLLHDAPQVFEPGELFSYNNAGYCVLGLLVETLRGKPYLQCLREDLIQPLELTHAAVDAAEAILHRAAVGHFQPDPDQPPQPAGVWALPRSLAPAGSALTMSARDLLTFARALMSDDGVLGGESIRAMRTEQVRLPVLWGNEDAWGLGLRLTLVDGVTVCGHNGDTIGQHAFLRFVPERDLAVVLLTNGGEVAAMFEELFGETLRELADVEPPALPVPGSGRIDASRYLGSYGNALMTVTVSQDDDEDVWAELVYTGADGIAVPPQRFQLLPYDGDTLVTAQPQRGVHQPRAFVGADEHGRARFLHMGRALARLPETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4S2</accession>
    <name>D3Q4S2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zwf</name>
        <name evidence="9" type="ordered locus">Snas_2419</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017673.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2419"/>
    <dbReference type="EnsemblBacteria" id="ADD42102">
        <property type="protein sequence ID" value="ADD42102"/>
        <property type="gene ID" value="Snas_2419"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2419"/>
    <dbReference type="eggNOG" id="COG0364">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013524_5_0_11"/>
    <dbReference type="OMA" id="VEICVYE"/>
    <dbReference type="OrthoDB" id="1153269at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="7">
        <location>
            <begin position="29"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="8">
        <location>
            <begin position="215"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="511" mass="57002" checksum="D885D943CA9371EC" modified="2010-04-20" version="1">MTATSSIANPLRDPQDRRLPHIPEPCALVIFGVTGDLARKKLIPAVYDLANRGQLPAAFVILGFARRDWDHGEFEELARDAAKAHARTPWREDVWNRLAGNFKFVPGSFDDDAAFDTLSATLDELRDTHAIPGNAAFYFSIPPGAFPTVLRQLERTGAADNSVSGGWRRVVVEKPFGNDLESARELDDVVDDVFTAEDVFRIDHYLGKETVQNIMALRFANALFEPVWNSHYVDSVQLTMAEDVGIGSRAGFYDSAGAARDVLQNHLLQLLALTAMEEPVGYAADEIRTEKLKVLRAITLPEDLETYAVRGQYSEGWVAGEKVRGYLAEDNIADGSTTETFVAVKLGVQNRRWAGVPFYLRTGKRLPRRVTEIAVVFKRAPHLPFHDYDTETLGQNQLVIRVQPDEGITVKFGSKVPGTGMELRDISMDFHYGEAFTESSPEAYERLIRDVLLGDKTLFPDAAEVEASWAVIDPLEEFWAGRKPSPYPAGTWGPQAAENMMDIDDRSWRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4V4</accession>
    <name>D3Q4V4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="5">3.2.1.52</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2451</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.52" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017705.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2451"/>
    <dbReference type="CAZy" id="GH84">
        <property type="family name" value="Glycoside Hydrolase Family 84"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42134">
        <property type="protein sequence ID" value="ADD42134"/>
        <property type="gene ID" value="Snas_2451"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2451"/>
    <dbReference type="eggNOG" id="COG3525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001501_3_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016231">
        <property type="term" value="F:beta-N-acetylglucosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102148">
        <property type="term" value="F:N-acetyl-beta-D-galactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011496">
        <property type="entry name" value="Beta-N-acetylglucosaminidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07555">
        <property type="entry name" value="NAGidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="SSF55545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049546" evidence="3">
        <location>
            <begin position="25"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_20b" evidence="4">
        <location>
            <begin position="64"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="581" mass="63470" checksum="91E0C130C05EFCAE" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q566</accession>
    <name>D3Q566_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019686.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4470"/>
    <dbReference type="EnsemblBacteria" id="ADD44115">
        <property type="protein sequence ID" value="ADD44115"/>
        <property type="gene ID" value="Snas_4470"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4470"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104207_0_0_11"/>
    <dbReference type="OMA" id="RTATCVE"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="19660" checksum="05BB31C351F9FAD6" modified="2010-04-20" version="1">MDPTIRQARDEDLPTLIDRLGQRFYFTERLRRQRQDRGRLFIALVDGRPAGDIYVSLEPADEPELRLHLRAVPLLQHLEVRDGLRNRGIGTRLITAAETFLKGLDFKQVALGVALDNHDAIRLYQQLDYREWIHSPTTTFREHFDSDGNVSRQQEQCRIFVKQLPQIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5C6</accession>
    <name>D3Q5C6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleic acid binding OB-fold tRNA/helicase-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019746.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4530"/>
    <dbReference type="EnsemblBacteria" id="ADD44175">
        <property type="protein sequence ID" value="ADD44175"/>
        <property type="gene ID" value="Snas_4530"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4530"/>
    <dbReference type="eggNOG" id="COG1200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144847_1_0_11"/>
    <dbReference type="OMA" id="TVFNPRY"/>
    <dbReference type="OrthoDB" id="1944256at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="127" mass="14245" checksum="D5EF94773B074B13" modified="2010-04-20" version="1">MPEHNRRRWAEILRRLTASEEDLYADQVRAESAKSGCRSCDSLERGVVAKVSGRITTVTFTPVATMPVLEAELYDGTSTVVLAWLGRRRIVGIEPGRRLIAAGRVAIRDEDRRVIYNPWYEIADTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5H9</accession>
    <name>D3Q5H9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6423</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021610.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6423"/>
    <dbReference type="EnsemblBacteria" id="ADD46039">
        <property type="protein sequence ID" value="ADD46039"/>
        <property type="gene ID" value="Snas_6423"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6423"/>
    <dbReference type="HOGENOM" id="CLU_1081460_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD46039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="257" mass="27769" checksum="256225D80F90D328" modified="2010-04-20" version="1">MTYPPQPGGYDPYGQQQPNYGPQSSGPPYQEPMTSVPSSPAGGYGQPAYPPQPPPGYGMSAPVPEPGERPQKVTVGAMSMVGLAVLWMFSALMGVVFYNQMSSNMEDYCKDLYSDTTYDYSSSCSDSMDTGGFQLFLNFFNFLWLLAFIIVALFALRGFSWARITSFILNGVSLAWNLIVMVCAGIFFAALESVSSSTSSSSSANVDDIIPGWYMPSVLIISILSMAISVVSLIMMANREAGDWFKANTQARAAGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q645</accession>
    <name>D3Q645_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin dehydrogenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2539"/>
    <dbReference type="EnsemblBacteria" id="ADD42220">
        <property type="protein sequence ID" value="ADD42220"/>
        <property type="gene ID" value="Snas_2539"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2539"/>
    <dbReference type="eggNOG" id="COG1319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058050_0_0_11"/>
    <dbReference type="OMA" id="MVEINFD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="SSF55447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="287" mass="30668" checksum="EA74CDC9026B2DB5" modified="2010-04-20" version="1">MTDMDFHRPATLTEALEYKARNPGAVPIAGGTDIMVELNFDVHRPAALLDLNPVTELAEWGNDGDRIRIGACVPYSRVINELGTRLPGLAIAARTVGSPQIRNRGTLGGNLGAASPAGDGHPPLVASGAHIELSSVRGVRRIPAPEFFTGVKRNVLEPDELITAILVPAARGPQQFAKIGTRNAMVIAVCAFALSLDPESRGVGTGIGSAAPTPRRATSAETFLSEALDWEKRSDIDETVSRRFGRLTAEAASPIDDVRGSAAYRRHALSVMARRTLGWAWKEYQCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6D1</accession>
    <name>D3Q6D1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pyridoxal 5'-phosphate synthase subunit PdxT</fullName>
            <ecNumber evidence="4">4.3.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Pdx2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Pyridoxal 5'-phosphate synthase glutaminase subunit</fullName>
            <ecNumber evidence="4">3.5.1.2</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pdxT</name>
        <name evidence="7" type="ordered locus">Snas_2628</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the glutaminase PdxT/SNO family.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="4"/>
    <dbReference type="EC" id="3.5.1.2" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017877.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2628"/>
    <dbReference type="MEROPS" id="C26.A32"/>
    <dbReference type="EnsemblBacteria" id="ADD42306">
        <property type="protein sequence ID" value="ADD42306"/>
        <property type="gene ID" value="Snas_2628"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2628"/>
    <dbReference type="eggNOG" id="COG0311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069674_2_0_11"/>
    <dbReference type="OMA" id="VFIRAPI"/>
    <dbReference type="OrthoDB" id="1628378at2"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006543">
        <property type="term" value="P:glutamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01749">
        <property type="entry name" value="GATase1_PB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01615">
        <property type="entry name" value="PdxT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002161">
        <property type="entry name" value="PdxT/SNO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021196">
        <property type="entry name" value="PdxT/SNO_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559">
        <property type="entry name" value="PTHR31559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01174">
        <property type="entry name" value="SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005639">
        <property type="entry name" value="Glut_amidoT_SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03800">
        <property type="entry name" value="PLP_synth_Pdx2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01236">
        <property type="entry name" value="PDXT_SNO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51130">
        <property type="entry name" value="PDXT_SNO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="L-glutamine binding" evidence="4 6">
        <location>
            <begin position="47"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="4 6">
        <location>
            <begin position="137"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4 5">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4 5">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="210" mass="22389" checksum="85DB1050D1EF8A90" modified="2010-04-20" version="1">MPVIGVLALQGDVPEHLAALERQHVKAVPVRRVEELDAVDALVIPGGESTAISKLLVAFDLLEPIRERLTRGMPALGSCAGMIMLASRVLDGRDDQQSLGALDITVRRNAFGRQVDSFETDVVLDGIDGGPFRTVFIRAPWVEDTGDDVEVIGRVSGGAADGKIVAVRAGTVMATAFHPEVTGDDRIHSAFVDLVRAATATAAEKQKEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6K2</accession>
    <name>D3Q6K2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4601</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4601"/>
    <dbReference type="EnsemblBacteria" id="ADD44245">
        <property type="protein sequence ID" value="ADD44245"/>
        <property type="gene ID" value="Snas_4601"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4601"/>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_5_11"/>
    <dbReference type="OMA" id="ISTAHEK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="5">
        <location>
            <begin position="23"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="262" mass="28827" checksum="F17D6B626FC17B95" modified="2010-04-20" version="1">MAQRTAPRNTPSPGARLEPVFRASTVDMIAERIREAILDGTLPPGAPLGEADMAHQLGVSRGPLREGMQRLAQEGLLGTVRRRGLAVVTMTPEDVSDVYLMRAAVERAAARQLLRSDPRHIKQTVKLLTTEQRKMSRAALRGSARLLSDSYLIFHRTLVDAAGSQRLSRSIRTLLVETRLCTFSIHGSFKVRAGLPESHEQLVQALAERDDPKVAALLETHMLEAVEWLTAPPKSVEDLETFAAPTPDSPQPLDRLELPEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6K7</accession>
    <name>D3Q6K7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4606"/>
    <dbReference type="EnsemblBacteria" id="ADD44250">
        <property type="protein sequence ID" value="ADD44250"/>
        <property type="gene ID" value="Snas_4606"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4606"/>
    <dbReference type="HOGENOM" id="CLU_2025321_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="122" mass="13058" checksum="5E8788BFE0B2CB8F" modified="2010-04-20" version="1">MKDLIAAIVEFPTVLFVVVGVAALVGAGVLVTRRRRVPRPDGERADLVGKTCVIREDGQGTGRAEVTDAEGATRVIRIRPAPEVRPNAETLRSGSSALIYDYDNTGGFFVVAPLAKKPERAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6T3</accession>
    <name>D3Q6T3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015903.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0618"/>
    <dbReference type="EnsemblBacteria" id="ADD40332">
        <property type="protein sequence ID" value="ADD40332"/>
        <property type="gene ID" value="Snas_0618"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0618"/>
    <dbReference type="HOGENOM" id="CLU_2883735_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="63" mass="6751" checksum="C37FB1E5EDDFEEE8" modified="2010-04-20" version="1">MPTQLARMGLVAAVFLISTSALLLVAFLKPGSAEFVITGITCGLGVFLGLFSTVVFYIERRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6U4</accession>
    <name>D3Q6U4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0629</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0629"/>
    <dbReference type="EnsemblBacteria" id="ADD40343">
        <property type="protein sequence ID" value="ADD40343"/>
        <property type="gene ID" value="Snas_0629"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0629"/>
    <dbReference type="eggNOG" id="ENOG5032Y3W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137977_0_0_11"/>
    <dbReference type="OMA" id="MEVTMSE"/>
    <dbReference type="OrthoDB" id="1637631at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="163" mass="18267" checksum="144CAF411B60CF9A" modified="2010-04-20" version="1">MVAFHHHQMKKVDAHMMYHLLKPEVPGEFGDNIDLDTSVHPPRVSVFHLSITDWLGDELLESFPCFAVTTALADKLTDAELTGFALADMEVTMSEEAYELMGDDAETPQLKWLQITGRPGHDDFGQTAKAHLVVSDRALETLRTHTLEHCVIQSWEPPSTESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Y8</accession>
    <name>D3Q6Y8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0674</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015958.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0674"/>
    <dbReference type="EnsemblBacteria" id="ADD40387">
        <property type="protein sequence ID" value="ADD40387"/>
        <property type="gene ID" value="Snas_0674"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0674"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036302_1_1_11"/>
    <dbReference type="OMA" id="WTVCDAV"/>
    <dbReference type="OrthoDB" id="311112at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007795">
        <property type="entry name" value="T7SS_EccB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044857">
        <property type="entry name" value="T7SS_EccB_R1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40765">
        <property type="entry name" value="PTHR40765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05108">
        <property type="entry name" value="T7SS_ESX1_EccB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03919">
        <property type="entry name" value="T7SS_EccB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="464" mass="49713" checksum="0D951F0E54CC4BE4" modified="2010-04-20" version="1">MRTKREQVQAHRFVIRRIVSGMIQGNPEAMEFPMRRTAGSMIGGLAIALLVFAGFWVVGALFNLGDWQEQDEGTIVVDEETGATYVYLKPALYPVENLTSARLFLEDGGEAPLVHVSTSDLHDVPRGDRFGIAGVPVAPPAADELVRLPWQVCSAPKDGNDKKQESHVTLEAPKAKDRLGGKGQLVVADEEYSLIWNDLRFPVPDPKVLPSVGLQAQDAVTVNNAFLQGIRVGPDLKVPEIPGGDDEHELPGNDDARNGDIFKSGKVTYVLTAEGFAEATEVGVLLLKKGNAPIPTDIDSDVVEDNHSDEPAQPEAWPDDANVMRDSPLTGKGVVCAVYDSADDDDVAVATYPADKAPEAITKAPSTTTDNDEDETSTADHVWTPGGRGALVRAVGTADATDGTVYLIADSKRFAVPEAALEPLGYGEVTPTPVPRSLVTLVPEGPSLDPEKVREGFTELPENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q769</accession>
    <name>D3Q769_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase H</fullName>
            <ecNumber evidence="6">2.1.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA m(4)C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytosine-N(4)-)-methyltransferase RsmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmH</name>
        <name evidence="8" type="ordered locus">Snas_2663</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10287"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74506"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.199" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2663"/>
    <dbReference type="EnsemblBacteria" id="ADD42340">
        <property type="protein sequence ID" value="ADD42340"/>
        <property type="gene ID" value="Snas_2663"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2663"/>
    <dbReference type="eggNOG" id="COG0275">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038422_0_0_11"/>
    <dbReference type="OMA" id="NPAKRTF"/>
    <dbReference type="OrthoDB" id="1272633at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="PTHR11265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="SSF81799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00006">
        <property type="entry name" value="TIGR00006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="43"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="290"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="336" mass="36877" checksum="0F6D7A6B3D254980" modified="2010-04-20" version="1">MMTKYGAPDRAHVPVFAERVCQLLAPAFDRPDPVCVDATLGAGGHSLALLEAHPSLTVIGIDRDPDALELAGKRLARFGDRFRPARAVYDELDEVLDETGVDQISGILFDLGVSSMQLDVAERGFAYAQDAPLDMRMDQSQGMTAAEVVNSYAERDLSRILRIYGEERFAPRIAKSIVAQRKRAPIESSRELADLVRDAVPAATRRRGGNPSKRTFQALRIEVNRELDVLRDALPRAIDALAPDGRIVVLSYHSLEDRIVKRELGERTKSSAPAGLPIDVPGTEPTLRWLTKGAQPPSEAEIAANPRAASAKLRAAQKLGGRNQDHDRHSQGEERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7B9</accession>
    <name>D3Q7B9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2714</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2714"/>
    <dbReference type="EnsemblBacteria" id="ADD42390">
        <property type="protein sequence ID" value="ADD42390"/>
        <property type="gene ID" value="Snas_2714"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2714"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_88_2_11"/>
    <dbReference type="OMA" id="GHYPSHW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="190"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="290" mass="32657" checksum="DF1B59DE38870A5D" modified="2010-04-20" version="1">MRAPTLDTERPDPVELHRLCVPDPERVPMAIGSFDSIGPLSRADFPHRHTFYELVLVTAGTGWHVVDFAAHPIRPPHLGFIAPGQVHWWRDAVGLDGQVLLFTDEFLLAHPRDREVWQALGRRPWLNLTGFERREFAALFAQLSAEYRRRDAGFLSVLQSYLHVLLVRACRVADGMALTMATDRPAAVVREFNRLVTHSGWSGYSVRDYATRLGVSVGYLTEVVKQVRGVTPGQLVRRARVLEARRLLGGSDLTIAQVSHALGFSDPAYFCRFFRRETGSTPGSFRRSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7P0</accession>
    <name>D3Q7P0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019953.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4740"/>
    <dbReference type="EnsemblBacteria" id="ADD44382">
        <property type="protein sequence ID" value="ADD44382"/>
        <property type="gene ID" value="Snas_4740"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4740"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_25_3_11"/>
    <dbReference type="OMA" id="AVIHECD"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16859">
        <property type="entry name" value="TetR_C_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="196" mass="21398" checksum="5D785EF829D6DDE0" modified="2010-04-20" version="1">MSESAKSRRRGAELVNAIHEAAIDELNEVGIGRLTMEGIARRSGAAKTSLYRRWPDTHALLIEALRERMPQETPSPGADDLRGDLIAALQLLCDWMMTPAARAVSAIVAGSGAHPEFTKRVFEEVFEAKGSRFTLTVLRHYADRGEIDPERVTPVVADIGEALVFKFSMDRFAMPAESDLAAIVDEAILPALGLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7P5</accession>
    <name>D3Q7P5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional repressor, CopY family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019958.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4745"/>
    <dbReference type="EnsemblBacteria" id="ADD44387">
        <property type="protein sequence ID" value="ADD44387"/>
        <property type="gene ID" value="Snas_4745"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4745"/>
    <dbReference type="eggNOG" id="COG3682">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119090_1_0_11"/>
    <dbReference type="OMA" id="AWATSDN"/>
    <dbReference type="OrthoDB" id="2027769at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019455">
        <property type="entry name" value="CopR_AtkY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="118" mass="13548" checksum="D86F933686A56A8B" modified="2010-04-20" version="1">MMRLGDLETAVMRVLWARGEPATVREVMAELDREPPLAYTTVMTVMDNLHRKELLSRERDGRAYRYRTVRSRAEHDAALMTEVLAASDDRQATLLKFVGSIEPEELDRLRRLMDGGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7R0</accession>
    <name>D3Q7R0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YCII-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019973.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4760"/>
    <dbReference type="EnsemblBacteria" id="ADD44402">
        <property type="protein sequence ID" value="ADD44402"/>
        <property type="gene ID" value="Snas_4760"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4760"/>
    <dbReference type="eggNOG" id="COG3795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130902_1_0_11"/>
    <dbReference type="OMA" id="GPYSETK"/>
    <dbReference type="OrthoDB" id="2051456at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="130" mass="14293" checksum="D9522D66D959DCF0" modified="2010-04-20" version="1">MKYMILVHASQQGYDQMFGDDPSWRDEHQAGLEKAMTDMNADLEKSGEFIDAVGLAAPVHTRQVVLKDGVPVVTDGPYAETQEVLAGYWMVECDSFDRATEIAARLARAPGHDTAVYVRPVLGDEPAPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7U2</accession>
    <name>D3Q7U2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0735</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016018.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0735"/>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40447">
        <property type="protein sequence ID" value="ADD40447"/>
        <property type="gene ID" value="Snas_0735"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0735"/>
    <dbReference type="eggNOG" id="COG3469">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019399_1_0_11"/>
    <dbReference type="OMA" id="CIQLEAG"/>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048727" evidence="5">
        <location>
            <begin position="32"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="6">
        <location>
            <begin position="47"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="341" mass="35641" checksum="D6156A2C8DAF1415" modified="2010-04-20" version="1">MSVTGKRYWRVAAVAAIALAASTGIALTSHADDTSTKDSSTAELPKHTLTGYWHNFDNGSTVKRLSDVPAEYNIVAAAFAEADASKPGAVTFGVSPEVSDALGGYSDDDFKADVKALQDKGQHVILSVGGEKGNVVVDDATKAANFASSVKSLMDEYGFNGVDIDLEHGINAQHMGAALKDLSSQAGDGLTITMAPQTIDMQSTSTEYFKLALDIKDILTVVNMQYYNSGSMNGCDGQVYAQGTVEFLTSLACIQLENGLSPSQVGLGLPATSQAAGGGHVDPAVVNAALDCLAKGENCGSHKPPKTYPDIRGAMTWSINWDATSDYAFAKTVGGHLSEMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Y6</accession>
    <name>D3Q7Y6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyridine nucleotide-disulfide oxidoreductase dimerization region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0779</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="2">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016062.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0779"/>
    <dbReference type="EnsemblBacteria" id="ADD40491">
        <property type="protein sequence ID" value="ADD40491"/>
        <property type="gene ID" value="Snas_0779"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0779"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016755_0_3_11"/>
    <dbReference type="OMA" id="CLMAVGA"/>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="3"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="4">
        <location>
            <begin position="346"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="182"/>
            <end position="189"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="3">
        <location>
            <begin position="39"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="463" mass="48411" checksum="FCE43593A40A77F7" modified="2010-04-20" version="1">MPSIVIIGGGPAGYEAALVAAQLDADVTLIEETGAGGACVLSDCVPSKTFIASSTARTSIDRAERLGVSAKDVTVDAQLVHDRVKMLALQQSGDICNKLVKSGVEYITGRARLTGVTEGFNHKVEILPVDGEAYEVDATVVLLATGATPRVLRDARPDGERVLSWRQVYDLEELPEKLIVVGSGVTGAEFASAYLAMGVDVTLVSSREHVLPHEDTDAAMAIESVFRERGMTIVPNARALKVCAEGDGVVAELADGQRLTGTHALMTVGSVPNTAGLGLAAAGVTCNDWGFVETDRVSRTNVPGVYAAGDVTGVQMLASVAAMQGRIAMWHALGETVKPLQLQTVAANVFTDPELATVGATQADVDSGKVPARSVTLPLEGNPRAKMSGFADGFVKLFCRPASGLVVGGVVVAPKASELILPISLAIQNHLTVEELARTVTIYPSMSGSLAEAARQLMQHEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q821</accession>
    <name>D3Q821_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016097.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0814"/>
    <dbReference type="EnsemblBacteria" id="ADD40526">
        <property type="protein sequence ID" value="ADD40526"/>
        <property type="gene ID" value="Snas_0814"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0814"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_49_0_11"/>
    <dbReference type="OMA" id="YGWIDDA"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="24"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="279" mass="29961" checksum="56477B06A5453034" modified="2010-04-20" version="1">MREIKTRDGRTLAVEEWGVPGGTPLLYAHGTPVSRLARYPYDEAFTERGIRQITFDRPGYGYSTANPGRRVADVAADMAAIADALELERFGVYGVSGGGPHALAFAAAYPERVSRVAVLACTAPRDAEGLDWTADMYQGNRDSATAAAQGREVLTAHLAAASGPNLKDLLPEAEQAVIAEPAVASMMQAAFAEAFRNGQDGWIDDELALYALPWGFDPADITVPVRLWHGERDTLVPPAHSDWLAARIPDATLVREPDAGHAGHFRATPSTLDWLLGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q839</accession>
    <name>D3Q839_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016115.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40544">
        <property type="protein sequence ID" value="ADD40544"/>
        <property type="gene ID" value="Snas_0832"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0832"/>
    <dbReference type="eggNOG" id="ENOG5033W9K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1045029_0_0_11"/>
    <dbReference type="OMA" id="VFSEREG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="279" mass="30663" checksum="AEBB40E863031558" modified="2010-04-20" version="1">MNENTVKIPVPVLVDTARSLWKANRFAEAGALLGSATGAGDDPRLALASAEVTIATDWFAGRATDPESLAEPKRVIDAHGDAETAWDLEFLFVRRGYGERLFSEAGRWRKVEAPDLEEMNALRTRAEALRDNAPDGRRRGWAEFYLGLIGDNVFSEREGSPAHYAQALRAGEEHADDHLLFEALRHLGDHDHDAGDLPLTRQRWERSAHHAARAGLVGSTLAQLMLVAVSARDDGDEGGAVLLATEVARWADAIGYERQRDMAESFVKGVDPTVQEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q841</accession>
    <name>D3Q841_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Hypoxanthine phosphoribosyltransferase</fullName>
            <ecNumber evidence="1 2">2.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0834</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>diphosphate + IMP = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:17973"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="2.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.8" evidence="1 2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016117.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0834"/>
    <dbReference type="EnsemblBacteria" id="ADD40546">
        <property type="protein sequence ID" value="ADD40546"/>
        <property type="gene ID" value="Snas_0834"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0834"/>
    <dbReference type="eggNOG" id="COG0634">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073615_0_0_11"/>
    <dbReference type="OMA" id="TMDWMAV"/>
    <dbReference type="OrthoDB" id="1819460at2"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052657">
        <property type="term" value="F:guanine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005904">
        <property type="entry name" value="Hxn_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01203">
        <property type="entry name" value="HGPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="3">
        <location>
            <begin position="31"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="195" mass="21587" checksum="4F038FC96314E7BB" modified="2010-04-20" version="1">MTPSAEHPGAPAAWYENDIDRVLVSETEIREKTAALAKQIDADYANTDGLLLVGLFKGAVMFMADLARALTIPVEMEFMALSSYGQRVTSSGVVRVLKDLDTDIKDRDVLVVEDVVDSGLTLSWLLKYLPSRGPRSVEMVSMLRKPKALETGINVKYVGFDVPDEFVVGYGLDYSERYRELPFVGVLKPSVYQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8A9</accession>
    <name>D3Q8A9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018054.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2807"/>
    <dbReference type="EnsemblBacteria" id="ADD42483">
        <property type="protein sequence ID" value="ADD42483"/>
        <property type="gene ID" value="Snas_2807"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2807"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119504_0_0_11"/>
    <dbReference type="OMA" id="GCPVECR"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="176" mass="18595" checksum="C6A06A7C4ED47749" modified="2010-04-20" version="1">MHDVDRTANLLGAAALAFTDLALDDATKAAGVSVSGAAALVTLTASPDISVTELGRRVGLSQSAAARMVDSLERSGLVERRPHAFNNRWVTVHPTRSGRQAARQLLVARGTPLTDAVAALDEDDQKALSDVLAKLLTRLYGEVGGSQYLCRLCDRKCCAANEPCPVGEAERNDAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8B9</accession>
    <name>D3Q8B9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2817</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2817"/>
    <dbReference type="EnsemblBacteria" id="ADD42493">
        <property type="protein sequence ID" value="ADD42493"/>
        <property type="gene ID" value="Snas_2817"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2817"/>
    <dbReference type="eggNOG" id="COG4779">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013016_1_1_11"/>
    <dbReference type="OMA" id="ARDAVWC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="336" mass="34753" checksum="7D4FB2571349C1D4" modified="2010-04-20" version="1">MWTLRLGRVSARVDARDAVWCGVFLVLLLAASLVTLTVGTIIVGFDEFTSLLSGTASRGTRIVVLEWRLPRLLFAIVAGAALGLAGMLMQSITRNPLGSPDIMGFDAGAYTGVLVMTLAVGVPTFLAKAIGASAGGLVAAAIVLFLALRGGVTGFRLIILGIGTAAMLTSVNSYLLLTASPEAAAGTAAWNAGSFANLAFEQLLPYLVLIVPLLALVVPVSRRLAQFTLGDDMAGTTGVSVNRTRIAATVLSVVIAAATTAVSGPLTFIALIAPQVAMRLARRDTASLPLIALNGALLLVAADYAAEWLTISTGLLTICVGGAYFVYVLMREGFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8D2</accession>
    <name>D3Q8D2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018077.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2830"/>
    <dbReference type="EnsemblBacteria" id="ADD42506">
        <property type="protein sequence ID" value="ADD42506"/>
        <property type="gene ID" value="Snas_2830"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2830"/>
    <dbReference type="eggNOG" id="COG2345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078469_1_1_11"/>
    <dbReference type="OMA" id="LLNCPFH"/>
    <dbReference type="OrthoDB" id="1288973at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="226" mass="24623" checksum="B9816575FCA00E31" modified="2010-04-20" version="1">MTHLSAVAALDEPTRRRLYDFVVSQPEPVSRDEAAAAEELPRTTAAFHLDRLVEAGLLSVVHERRSGRTGPGAGRPAKLYHRSDRQITVSLPERRYDLAGQLLAAALSEAENSGESPRAILDRRARTLGTDIGLAARSLHPEVSTEDSVVRTLAEQGFEPRVSGDHILLGNCPFHDLARQQPELVCGMNLCLLDGLLNGLGMRGLSPRLNPTRNHCCVRLEPTDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8G8</accession>
    <name>D3Q8G8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Virginiamycin B lyase</fullName>
            <ecNumber evidence="1 2">4.2.99.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1 2">Streptogramin B lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">vgb</name>
        <name evidence="3" type="ordered locus">Snas_2867</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1 2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Vgb family.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.-" evidence="1 2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018113.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2867"/>
    <dbReference type="EnsemblBacteria" id="ADD42542">
        <property type="protein sequence ID" value="ADD42542"/>
        <property type="gene ID" value="Snas_2867"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2867"/>
    <dbReference type="eggNOG" id="COG4257">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054751_1_0_11"/>
    <dbReference type="OMA" id="ALWFTEW"/>
    <dbReference type="OrthoDB" id="966287at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016835">
        <property type="term" value="F:carbon-oxygen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017001">
        <property type="term" value="P:antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01282">
        <property type="entry name" value="VirginiamycinB_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011217">
        <property type="entry name" value="Streptogrm_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026412">
        <property type="entry name" value="Streptogrm_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR026412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="291" mass="29883" checksum="B726620B128904E1" modified="2010-04-20" version="1">MTATITEHVVTDAAGGPYALTSGPDGALWITLVHGGRIARFVPGTEATAHELAPGSGPMIIAPGPDNALWFTQNRAHSIGRLTTDGDLTEYPLPTPDCGPFGIAAGPDGALWFTEMTGDRVGRISVDGKVTEYPLPMTGGMASAITAGRDDGMWFTLNQANAIGRVGMDGDITVHALPTEAAGPVGICAGPDGALWFVEIGAGQIGRITVDGTITEFPLPDRAARPHAITAHDGALWFTEWGANRVGTIDPSGAVTVHDLPTPGSEPHGIATGPDGALWTALETGALARIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8J2</accession>
    <name>D3Q8J2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4793</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020005.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4793"/>
    <dbReference type="EnsemblBacteria" id="ADD44434">
        <property type="protein sequence ID" value="ADD44434"/>
        <property type="gene ID" value="Snas_4793"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4793"/>
    <dbReference type="eggNOG" id="ENOG5032TPU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117223_1_0_11"/>
    <dbReference type="OMA" id="VGKDWSG"/>
    <dbReference type="OrthoDB" id="1912696at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021412">
        <property type="entry name" value="DUF3052"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11253">
        <property type="entry name" value="DUF3052"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="140" mass="14915" checksum="D6115F97B2769B65" modified="2010-04-20" version="1">MSATAGSADGVRTIIDKLGIDTDAVVMEIGFDSDIDSALREAVIARVGELHDEDTDEVVDVVLLWWRDEDGDLVDVLMDARSPLSEEGVVWLLTPKPGRDGHIESAEISEAAPTAGLSSTSSVNAGEDWVATRLVAPRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9B4</accession>
    <name>D3Q9B4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018167.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2921"/>
    <dbReference type="EnsemblBacteria" id="ADD42596">
        <property type="protein sequence ID" value="ADD42596"/>
        <property type="gene ID" value="Snas_2921"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2921"/>
    <dbReference type="eggNOG" id="COG3222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075662_0_0_11"/>
    <dbReference type="OMA" id="CDAWFGP"/>
    <dbReference type="OrthoDB" id="1445278at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018641">
        <property type="entry name" value="Trfase_1_rSAM/selenodom_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36529">
        <property type="entry name" value="PTHR36529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09837">
        <property type="entry name" value="DUF2064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="211" mass="22747" checksum="CC9761ADB8F86E74" modified="2010-04-20" version="1">MTNLLIIAKQPLPGRVKTRLSPRYSPAEAARLAEAALSDTLTVAAGLAAERRVLVLDGEPGDWLPSGFEVIPQHGHGLDERLANAFDDCGGTSLLIGMDTPQVTHEMLAPVVESGDWDCDAWFGPAADGGFWALGLRRPDRRLLLGVPMSQDHTGVVQRQRLVDVGLRVRDLLPLRDVDTPGDVDTVAALAPDSRFAATARRLRHPRKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9H2</accession>
    <name>D3Q9H2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 10">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="2 7 10">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgk</name>
        <name evidence="12" type="ordered locus">Snas_2980</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 10">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7 11">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 10">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="2 7 10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018225.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2980"/>
    <dbReference type="EnsemblBacteria" id="ADD42654">
        <property type="protein sequence ID" value="ADD42654"/>
        <property type="gene ID" value="Snas_2980"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2980"/>
    <dbReference type="eggNOG" id="COG0126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025427_0_2_11"/>
    <dbReference type="OMA" id="DMIFDIG"/>
    <dbReference type="OrthoDB" id="462069at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00318">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="22"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="60"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <begin position="354"/>
            <end position="357"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD42654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="399" mass="41943" checksum="B688016CFCF602A4" modified="2010-04-20" version="1">MRTLETLLEQGVTGRRVLVRADLNVPLDGDRITDDGRIRGVLPTLTALRDAGAKLVVCAHLGRPKGAPDAKYSLAPVAVRLSELLGTTVGFATDTVGTDAERALSALGDGGVVLLENLRFNPGETSKDDAERLDFATKLAEGNDFYVDDAFGAVHRKHASVYDVATLLPHYAGKLITTEVSVLKRLTESPQRPYTVVLGGAKVSDKLAVIANLLDKVDRLLIGGGMMFTFLAAQGHDVGTSLLESDQIDTCKGFLDEAAKRGVELVLPSDTITAAQFSAEAEPETVAVDAIPSDRMGLDIGPETAARFAVEIGKSKTVFWNGPMGVFEFSAFADGTRTVARALVDSDAFTVVGGGDSAAAVRTLGLPEDGFGHISTGGGASLEYLEGKTLPGLSILESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9P1</accession>
    <name>D3Q9P1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4946</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4946"/>
    <dbReference type="EnsemblBacteria" id="ADD44587">
        <property type="protein sequence ID" value="ADD44587"/>
        <property type="gene ID" value="Snas_4946"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4946"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="DVWVPPD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="151"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="224" mass="24207" checksum="FECF2EF5BB5C22DB" modified="2010-04-20" version="1">MSDVIRVLLADDQALVRAGFRALLDSCDDISVVGEANDGEEAFRLIRDMVPDVVLMDIRMPGLDGLAATAKITAEASLTSVRIIILTTFDLDEYVFEALRSGASGFLVKDTEPVELLQAVRVVARGDALLSPGVTRRLVAEFAQRAKEPVSAKKLEQLTEREREVVALAGTGLSNEEIGAKLFLSPATAKTHISRAMIKLGARDRAQLVVFAYESGLVRPGWLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAR0</accession>
    <name>D3QAR0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane-flanked domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020277.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5070"/>
    <dbReference type="EnsemblBacteria" id="ADD44706">
        <property type="protein sequence ID" value="ADD44706"/>
        <property type="gene ID" value="Snas_5070"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5070"/>
    <dbReference type="eggNOG" id="COG3402">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104197_4_0_11"/>
    <dbReference type="OMA" id="WRYEIRE"/>
    <dbReference type="OrthoDB" id="1768296at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="79"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="169" mass="18857" checksum="B22313557F539D2C" modified="2010-04-20" version="1">MNVVAPGEKPRLRPPRNRIDRRAVLWWTLRALIGSVVFVGGGLVAFALFPDARPWVWPPLVLFAVIGLVLTLITPRWRYRVHRWEVTDEAVYTATGWFTKEWRVAPMSRIQTVDTERGPLQQWLGLAKVTVTTASSAGNIEIEGLDAEVAERVSRQLADAAGLTEGDAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAS2</accession>
    <name>D3QAS2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5082"/>
    <dbReference type="EnsemblBacteria" id="ADD44718">
        <property type="protein sequence ID" value="ADD44718"/>
        <property type="gene ID" value="Snas_5082"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5082"/>
    <dbReference type="HOGENOM" id="CLU_1189327_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="233" mass="24698" checksum="BEFE7E747DFC0A14" modified="2010-04-20" version="1">MRVLGIIAAAVVFLPGLVMPVVLFAKGESFVTKSGTRISGGELLVGVLCVMVFIASCAVFGVWLRRKQRQATPEAPVPQRLGIGQAGLWWTAADGATHVGWDAVEGVRIHSVLQSRGGGGGGAAQLISVDLMGAVPPEAAGRAPAFNQGAVFLRIGLPEAFGPTRHFPLRLAMDIGLAVRAFRPELWRGFTLDSGHGYVEFLSWDNAVPPMFPGFQTPTWNNFGGGRQSGPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB06</accession>
    <name>D3QB06_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016394.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1113"/>
    <dbReference type="EnsemblBacteria" id="ADD40823">
        <property type="protein sequence ID" value="ADD40823"/>
        <property type="gene ID" value="Snas_1113"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1113"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_2_11"/>
    <dbReference type="OMA" id="FERYGKR"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="311" mass="35440" checksum="504797FB135DF896" modified="2010-04-20" version="1">MELLALRYFQTVARTENISRAAERLRIAQPSLSRTIARLESELKVPLFDRRGRNISLNRFGVAFLHRVDKALAELDDARRELTESAGLERGGFAIASETLLTVTDTMSEFLTEYPDVEVRLYQATGDEMRQLLQSRQVDMCLASQQLTDPSFTGVEVIREEVLLAVPPHHRLANQTRVTLADIADEPFITTRPGYWLRTLLDRLFADAGLRPVIRCEGDEPGVIQTMISTGLGIGLNPSQARYSDIRTDVAWLHLDAPDCHRVLRLYWNTDAFVSQAARRFRDFTIERLRQQLSTPPALAVARTRRRPWHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB62</accession>
    <name>D3QB62_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Virulence factor Mce family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1169</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016450.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1169"/>
    <dbReference type="EnsemblBacteria" id="ADD40879">
        <property type="protein sequence ID" value="ADD40879"/>
        <property type="gene ID" value="Snas_1169"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1169"/>
    <dbReference type="eggNOG" id="COG1463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026704_1_0_11"/>
    <dbReference type="OMA" id="FQFYLCG"/>
    <dbReference type="OrthoDB" id="807474at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005693">
        <property type="entry name" value="Mce"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024516">
        <property type="entry name" value="Mce_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11887">
        <property type="entry name" value="Mce4_CUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00996">
        <property type="entry name" value="Mtu_fam_mce"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MlaD" evidence="1">
        <location>
            <begin position="45"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Mce4_CUP1" evidence="2">
        <location>
            <begin position="127"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="356" mass="37584" checksum="413B635854B0D2B6" modified="2010-04-20" version="1">MARRSGPTTFGSGLKLGVFAVITSLALVLLTDALGGVSLPGAAGYTAMFEDATGLLPGDEVRIAGAKVGEVDDVELEQGNKPLAKVTFDLDEDRDIPESVHATIRYRNMVGQRYIALTQAADGESPSAKNLEPGDVIGVRQTSPALDLTVLLNGFKPLFAALSPDEVNSLSYEIIQTLQGEGSTVESLLSHTASLTSTLAENDETIGKVITNLNDILSTVADRDEELDTSIGRLQEFVSGLSEDREALGEAVSSIGTLTTQTSQLVTDARPALDADISALDELSTTLLDNSATIEDALHDLPNTYQELTTTASYGSWFNFFLCDFDGELGVTDEVTINPVAIHSPQPRCDATGGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBC0</accession>
    <name>D3QBC0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chorismate dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.151</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Menaquinone biosynthetic enzyme MqnA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mqnA</name>
        <name evidence="4" type="ordered locus">Snas_1227</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>chorismate = 3-[(1-carboxyvinyl)-oxy]benzoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:40051"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:76981"/>
            <dbReference type="EC" id="4.2.1.151"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MqnA/MqnD family. MqnA subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.151" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016508.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1227"/>
    <dbReference type="EnsemblBacteria" id="ADD40937">
        <property type="protein sequence ID" value="ADD40937"/>
        <property type="gene ID" value="Snas_1227"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1227"/>
    <dbReference type="eggNOG" id="COG1427">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059898_0_0_11"/>
    <dbReference type="OMA" id="WGLARTG"/>
    <dbReference type="OrthoDB" id="1062841at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00995">
        <property type="entry name" value="MqnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003773">
        <property type="entry name" value="Menaquinone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030868">
        <property type="entry name" value="MqnA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37690">
        <property type="entry name" value="PTHR37690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02621">
        <property type="entry name" value="VitK2_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="282" mass="30314" checksum="3A93D74B01E3A999" modified="2010-04-20" version="1">MSGLRRPRVGHIEFLNCLPIYWGLMRSGALIDVDLTRDTPVALNDRLVAGELDIAPISLVEYLRHADDLLLLPGPAVGSDGPVLSVNIVHERPLTELDGARVALGSASRTGVLLARMLLADHYGIDATYFSCAPDVPQMLRKADAAVVIGDVALRALYEAPEQGLTVTDLGEQWKAWTGLPMVFAVWAVRREFAAAHPGQVKDVHDALTRSVSLCLDELDIVAASAARWEPFDAATLAGYFRTLDFSLGERQLTGLREFAARAAALGEAPPLAVGGPLLFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBC6</accession>
    <name>D3QBC6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016514.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1233"/>
    <dbReference type="ESTHER" id="stanl-d3qbc6">
        <property type="family name" value="Duf_1023"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40943">
        <property type="protein sequence ID" value="ADD40943"/>
        <property type="gene ID" value="Snas_1233"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1233"/>
    <dbReference type="eggNOG" id="COG4099">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025057_2_1_11"/>
    <dbReference type="OMA" id="RASHEGQ"/>
    <dbReference type="OrthoDB" id="2018813at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010427">
        <property type="entry name" value="DUF1023"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038332">
        <property type="entry name" value="PPE_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06259">
        <property type="entry name" value="Abhydrolase_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="261"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="494"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="508"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="563" mass="60396" checksum="DD00D5D0CD4ED28E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBS4</accession>
    <name>D3QBS4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Substrate-binding region of ABC-type glycine betaine transport system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5178</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020384.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5178"/>
    <dbReference type="EnsemblBacteria" id="ADD44813">
        <property type="protein sequence ID" value="ADD44813"/>
        <property type="gene ID" value="Snas_5178"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5178"/>
    <dbReference type="eggNOG" id="COG1732">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038355_1_0_11"/>
    <dbReference type="OMA" id="APMNNTY"/>
    <dbReference type="OrthoDB" id="770506at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049038" evidence="2">
        <location>
            <begin position="27"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="47"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="337" mass="36834" checksum="F2EF2A64F5E21C0F" modified="2010-04-20" version="1">MRRTKLLLTGALVAVLAACGLEPASQSVPDVQGGPELAEFDNLGEAPIVTTSKDFTEQLILGKMLSLVLKAKGADVADHTNTKGSVNARETILNGSSDIAWEYTGTAWLVYMGHSDVDPKTSEAGGVKISDPEALYEAVKKADLKDNDVVWGDPAPFNNTYAMAIKEDQAKQKDANGKTIDVKSLSDLAKLPPDKQTYCLENEFENRPDGWPGMQQAYDIDVPKDNVTIMDTGVIYSRIGGGSCLAGEVFDTDGRIPANGLRTLEDDKGYFPIYEPAVTIREEIHKKHPQIVQMFNKLGSKLSTETMRRLNAEVDVDGRDPLDVAREWLVDEGFLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBU0</accession>
    <name>D3QBU0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histidinol-phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Histidinol-phosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_5194</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-histidinol phosphate = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020400.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5194"/>
    <dbReference type="EnsemblBacteria" id="ADD44829">
        <property type="protein sequence ID" value="ADD44829"/>
        <property type="gene ID" value="Snas_5194"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5194"/>
    <dbReference type="eggNOG" id="COG0483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044118_4_0_11"/>
    <dbReference type="OMA" id="WRTRAYG"/>
    <dbReference type="OrthoDB" id="1741160at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00013"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011809">
        <property type="entry name" value="His_9_proposed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02067">
        <property type="entry name" value="his_9_HisN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD44829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="266" mass="28762" checksum="FD94E68B3E3E8324" modified="2010-04-20" version="1">MSSYADDLGLAHMLADSADSISAERFRSLDLRVEHKPDMSHVTDADTAIEKALRSTLARARPRDGVVGEEFGEEHGSGGRRWVIDPIDGTANFVRGVPVWATLIALFEGSQPVVGVVSAPVVGRRWWAAKGTGAFAGRHRNRAQRIQVSGVRRLANASISYSSLPSWFEYDRGPQMVDLLRGAWRSRAYGDFYSYVLVAEGAVDVAMEPEVNLWDLAPLSVIVTEAGGTFTDLDGNPGPSGGSAIASNGLLHDAVREALRPTSNEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTW7</accession>
    <name>D3PTW7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Snas_0002</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the beta sliding clamp family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015296.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0002"/>
    <dbReference type="EnsemblBacteria" id="ADD39725">
        <property type="protein sequence ID" value="ADD39725"/>
        <property type="gene ID" value="Snas_0002"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0002"/>
    <dbReference type="eggNOG" id="COG0592">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038149_1_1_11"/>
    <dbReference type="OMA" id="YLIMPVR"/>
    <dbReference type="OrthoDB" id="1040142at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5 9 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="10">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="11">
        <location>
            <begin position="127"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="12">
        <location>
            <begin position="250"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD39725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="380" mass="39515" checksum="E0EC68351AED9A7E" modified="2010-04-20" version="1">MKLRVDRDALADAVAWTAKSLPVRPSVPVLAGALMTVSDGQLTISGFDYEVSSQVTLPVTSDASGSALVSGKLLAEIVKALPAKPVDVAAEGSHVEITCGSARFTLPTMPVEDYPSLPDMPEAVGTIDAAAFAAAVAQTAVAAGKDDTLPTMTGVQLEFTGTGLALLATDRYRMAIRDLPWRPDSNDLNVTTLIPAKALSDTAKALGSRGGEVTIALPDPSNGPIGMVGFAADGRRTTSRVLDGQLPPLRSLIPVTYAAELRVNAAELASVARRVSLVTERNSPLRLNVDGDGLVVEAGGAEDATASEAMDCEYSGDAMKVAFNPQYLLDGLSAISAPVAVFSFTEPGKPVTLKGDKANADDDGDFSGYTHLLQPLRYDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU31</accession>
    <name>D3PU31_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016548.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1268"/>
    <dbReference type="EnsemblBacteria" id="ADD40977">
        <property type="protein sequence ID" value="ADD40977"/>
        <property type="gene ID" value="Snas_1268"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1268"/>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_0_1_11"/>
    <dbReference type="OMA" id="RYSQWKQ"/>
    <dbReference type="OrthoDB" id="1064766at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="PTHR22893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="14"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="371" mass="39328" checksum="1D9B6A1D711C0B12" modified="2010-04-20" version="1">MADNGTRAATILNRPIQLGELSLRNRIAMAPMTRQFSPGGVPDADVAAYYARRAAGGVGLIVTEGTYIGHESAGSSDRVPRFHGEDALAGWAAVADAVHAAGGRVFPQLWHVGMDRAAGTPPVAEAPPMGPSGIPLDDRPAGKTMTPTDLDEVIEAFATAAAAAQAAGFDGVELHGAHGYLIDQFLWEHTNRRTDSYGGDIAGRTRFAAEIVSACRAAVTPGFPISFRMSQWKMGAYQAKLAESPQELDAVLAPLARAGVDAFHCSTRRYWLPEFDGCDLNLAGWVKKLTGKPTITVGAVGLANEFLQSLQGDQTDATSIDGLLDRLEADEFDMVAVGRALLADPAWAAKTLAGRHDQVTPFEPSMLGRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU55</accession>
    <name>D3PU55_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="1">PTH</shortName>
            <ecNumber evidence="1 2">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pth</name>
        <name evidence="4" type="ordered locus">Snas_1292</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PTH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1 2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016572.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1292"/>
    <dbReference type="EnsemblBacteria" id="ADD41001">
        <property type="protein sequence ID" value="ADD41001"/>
        <property type="gene ID" value="Snas_1292"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1292"/>
    <dbReference type="eggNOG" id="COG0193">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062456_2_2_11"/>
    <dbReference type="OMA" id="HVLSKFH"/>
    <dbReference type="OrthoDB" id="1676462at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PTHR17224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="SSF53178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01195">
        <property type="entry name" value="PEPT_TRNA_HYDROL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="213" mass="22908" checksum="B42E7645E3C60BD9" modified="2010-04-20" version="1">MADSPYLIVGLGNPGPKYAGNRHNVGFMVADLLAERVGGSMKRAAKVRAEVCQGRLSIGGPQVILVKPLTYMNVSGQAVAPLAVFFKVPAERIIVVHDELDLPYGVVRLKAGGGENGHNGLKSTSQALGDKGYVRARFGIGRPPGRIDPAAFVLRDFSPAEKKELPLFVDLTADAVSEVVESGLVKAQNKFHALSLYFLIFRGIPVTLGRFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUC2</accession>
    <name>D3PUC2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1361</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016639.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1361"/>
    <dbReference type="EnsemblBacteria" id="ADD41068">
        <property type="protein sequence ID" value="ADD41068"/>
        <property type="gene ID" value="Snas_1361"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1361"/>
    <dbReference type="eggNOG" id="ENOG5031FHG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126433_1_0_11"/>
    <dbReference type="OMA" id="YAHIPFP"/>
    <dbReference type="OrthoDB" id="2025483at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13564">
        <property type="entry name" value="DoxX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="124" mass="12576" checksum="D394D618865190D2" modified="2010-04-20" version="1">MNAAYLTLTLITAAANLFSGGLALAGFAPIYPAMAKAGVPASWVRFPIGTLKTAGALGLLAGLWLPMLGTAAAIGLVLFFVCAIHTHLLARDRSPQLALAVAFLTLAVATLTSGIATGNVSECH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUC8</accession>
    <name>D3PUC8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018512.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3271"/>
    <dbReference type="EnsemblBacteria" id="ADD42941">
        <property type="protein sequence ID" value="ADD42941"/>
        <property type="gene ID" value="Snas_3271"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3271"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_5_2_11"/>
    <dbReference type="OrthoDB" id="1677723at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="127" mass="14440" checksum="EC11B2EC7FF3C61E" modified="2010-04-20" version="1">MTEGDPLTPIRTVSEHFAVPISTLHYWERRGLISPRRQAGQRFYDADQLYRVALIKMWRTTGRIGIPEIARMLGAPGWQDTIAEQLSQLEEQLAALTAAHSYLTRLSNCRQSTPERCPEFRASVDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUE8</accession>
    <name>D3PUE8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018532.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3293"/>
    <dbReference type="EnsemblBacteria" id="ADD42961">
        <property type="protein sequence ID" value="ADD42961"/>
        <property type="gene ID" value="Snas_3293"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3293"/>
    <dbReference type="eggNOG" id="ENOG502ZFB5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037742_0_0_11"/>
    <dbReference type="OMA" id="YWHDYAR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="393" mass="43813" checksum="1973A942CB933F11" modified="2010-04-20" version="1">MRTLFDGEFNVSYGQLYLDGRIDPDEGAEPDLDNCFMGQTVGLMGAAIPGHLFVLTGTHSGSVPLTVEVHETEPSLDADAWEDVVEVSFESDADEVALIEWDGDFQSLDLSPGSYRVRYLCRGMDAASGHDRFDDDPVVDEYLLQFWPAPPQRDRIVKETSRSAAYWRRVAAEVPPPPSPEEVAEAKRIADERAAEKRRRYAERERWGEYSPSDRLRGLGGHVSKVAKRDPALAHATEAAGPDVQRAIACWAARRFCDATGLSDVDWIAEGLSQLERGVPLSPPLDDVEQTWRRFVEDPRVRDIVGPKLDRVPDAARQEMPFPALTEAAHPDPLRAAFDALWAASAGSGWRDVFTEVRERFPRLSAPPLPPEEPSRSQVSMTVVRRRASDEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUM9</accession>
    <name>D3PUM9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3378</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3378"/>
    <dbReference type="ESTHER" id="stanl-d3pum9">
        <property type="family name" value="Carb_B_Bacteria"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43042">
        <property type="protein sequence ID" value="ADD43042"/>
        <property type="gene ID" value="Snas_3378"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3378"/>
    <dbReference type="eggNOG" id="COG2272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_13_0_11"/>
    <dbReference type="OMA" id="IFFYEFQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005126346" description="Carboxylic ester hydrolase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="COesterase" evidence="3">
        <location>
            <begin position="31"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="525" mass="57162" checksum="5DA7F4FD9570264D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUN7</accession>
    <name>D3PUN7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NB-ARC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3386</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3386"/>
    <dbReference type="EnsemblBacteria" id="ADD43050">
        <property type="protein sequence ID" value="ADD43050"/>
        <property type="gene ID" value="Snas_3386"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3386"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="NB-ARC" evidence="2">
        <location>
            <begin position="147"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="740"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="834" mass="92468" checksum="8B3FF69C76DD70B3" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUS8</accession>
    <name>D3PUS8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5318</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020523.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5318"/>
    <dbReference type="EnsemblBacteria" id="ADD44952">
        <property type="protein sequence ID" value="ADD44952"/>
        <property type="gene ID" value="Snas_5318"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5318"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113263_0_0_11"/>
    <dbReference type="OMA" id="EPEFRAD"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="197" mass="21381" checksum="8767D4016D8B6E1F" modified="2010-04-20" version="1">MTEDQAPPRRLPRAQRRDQILAAATSAFARTGFADTSLDDVSAAAGVSKAILYRHFESKTELYRAVLDRICAKLDATVGTDDHDDESIPTLMRAAATDPDGFRLLFRYAAREPEFRSFVDTMSGESTRIALRQLTADIPDPRWAGWAAQLAPVITIEATLAWLDAGQPDPELAAERVKDLIAALITTAAASGENPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV24</accession>
    <name>D3PV24_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="5">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">clpP</name>
        <name evidence="8" type="ordered locus">Snas_1370</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 7">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016648.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1370"/>
    <dbReference type="MEROPS" id="S14.008"/>
    <dbReference type="EnsemblBacteria" id="ADD41077">
        <property type="protein sequence ID" value="ADD41077"/>
        <property type="gene ID" value="Snas_1370"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1370"/>
    <dbReference type="eggNOG" id="COG0740">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058707_3_2_11"/>
    <dbReference type="OMA" id="RDYWMKA"/>
    <dbReference type="OrthoDB" id="1728970at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="207" mass="22510" checksum="217CD718A596CE91" modified="2010-04-20" version="1">MTHPFLPVARGGDDPANGFDDMVFNRLLKERIVFMGTEVNSQVANRVSAQLLLLAADDPERDINLYINSPGGSVYDGMAIYDTMQFISNDVATIAMGMAASMGQLLLCAGTPGKRYALPHARIMMHQPSGGIGGTASDVAILAEQMAYTKKMFQERVSTHTGRTLDEIERDSDRDRWFTAEEAKEYGFIDQVITGAGQVPTGAGTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVA2</accession>
    <name>D3PVA2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016726.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1449"/>
    <dbReference type="EnsemblBacteria" id="ADD41155">
        <property type="protein sequence ID" value="ADD41155"/>
        <property type="gene ID" value="Snas_1449"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1449"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_6_11"/>
    <dbReference type="OMA" id="GEFMENA"/>
    <dbReference type="OrthoDB" id="1616572at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="275" mass="28910" checksum="D2F0235C0739A74F" modified="2010-04-20" version="1">MTILVTGATGNVGRVLVEQLVAAGESVRGLTRDPSRAALPDGAEAVAGDFGDPDSVTAALEGVEAVFLLAMLALETPKVAELFPAAGVRRVVTMTTDAIDEDIDLGQFRAVEAAVEATGLEWTHVRPGEFALNKRDFWGPTIKADGVVCSAYPDAIGAPVHEADIAAVAATALTAEGHNGRIYRLRGPQSSHRQQAAAIAAATGREIRVERVTHNAERAQMIAQGVPAWAADHVLSYPVRWADEPCETTADVELVTGAPARDFGQWAADHAADFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVC1</accession>
    <name>D3PVC1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4190 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1470"/>
    <dbReference type="EnsemblBacteria" id="ADD41174">
        <property type="protein sequence ID" value="ADD41174"/>
        <property type="gene ID" value="Snas_1470"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1470"/>
    <dbReference type="eggNOG" id="ENOG5030J63">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2248461_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025241">
        <property type="entry name" value="DUF4190"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13828">
        <property type="entry name" value="DUF4190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4190" evidence="2">
        <location>
            <begin position="22"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="104" mass="10910" checksum="30A9B4D32537A313" modified="2010-04-20" version="1">MTEPRTDPMSTTPTPAREMNGLAVASFSVAMVGLCSPLGILGLIMGYVARGQIRERNNSGEGLAKASIILGWISIIAFILLLVLGIAGGIFAAISEGEWGKNYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVC9</accession>
    <name>D3PVC9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Adenine phosphoribosyltransferase</fullName>
            <shortName evidence="10">APRT</shortName>
            <ecNumber evidence="5 10">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">apt</name>
        <name evidence="12" type="ordered locus">Snas_1478</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="5 10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016753.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1478"/>
    <dbReference type="EnsemblBacteria" id="ADD41182">
        <property type="protein sequence ID" value="ADD41182"/>
        <property type="gene ID" value="Snas_1478"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1478"/>
    <dbReference type="eggNOG" id="COG0503">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063339_3_0_11"/>
    <dbReference type="OMA" id="KPGIVFR"/>
    <dbReference type="OrthoDB" id="1532478at2"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="11">
        <location>
            <begin position="30"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD41182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="170" mass="18347" checksum="24B517C4AD4C3530" modified="2010-04-20" version="1">MDLNDYVTAVEDFPITGVSFKDITPMLAAPAAFDHSVELLCQTARTLGGDKIAAFDARGFLWAAPMAVRLRLPLVPIRKKGKLPRATSSTSYKGEYGTETVEMHTDAIASGERILLVDDVIATGESMRAGAKLVEELGGTVTACLAVIELTYLGAQDLLKDLRVDSLLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW75</accession>
    <name>D3PW75_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016803.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1528"/>
    <dbReference type="EnsemblBacteria" id="ADD41232">
        <property type="protein sequence ID" value="ADD41232"/>
        <property type="gene ID" value="Snas_1528"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1528"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_25_6_11"/>
    <dbReference type="OMA" id="ERRTNCV"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16859">
        <property type="entry name" value="TetR_C_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="194" mass="21306" checksum="914C0F7E67C1EE89" modified="2010-04-20" version="1">MTSHTRRPGTGPRQAERLYRVVLELLREHGFDELAIETVAQRAGVNKTTIYRWWPSKDALVADALIHSELLDLDVPDTGSLRGDLTALVRQVRLLLSGADTAPIATSVFAAAASRPELAGLTRDFFADRLSRERVVFERAIARGDIHPDTDVTLAVDLALGAVWTRVVLRQQDVGEAFDAEVTDLLLAGLTPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWD5</accession>
    <name>D3PWD5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase associated with various cellular activities AAA_3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1589</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016863.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1589"/>
    <dbReference type="EnsemblBacteria" id="ADD41292">
        <property type="protein sequence ID" value="ADD41292"/>
        <property type="gene ID" value="Snas_1589"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1589"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034716_2_0_11"/>
    <dbReference type="OMA" id="THAATEV"/>
    <dbReference type="OrthoDB" id="895310at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="47"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="241"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="341" mass="37714" checksum="7DD053714586162B" modified="2010-04-20" version="1">MTQQTEPLSLSEVAKHAADVLDAVNTVIVGKREPLELVLAGILAKGHVLFEDYPGLGKTLTARCFAQSLGLEFNRLQFTPDLLPADVTGSFMYNQKSGDFDFRPGPVFTNLLLADEINRTPPKTQAALLEAMQEQQVSVEGSTRRLEPPFCVLATANPIEYEGTYPLPEAQLDRFLARVSFGYPNEDEEWTVLKRRMARQQEESFLDPVVDASTLVRMQRALETVSVEDSIGQYIVRIVAATRDHDDIQVGASPRGSLALLLLGRARAVMAGRDYVIPEDVKTVAPAALSHRVSLRPELWLRHASPERIIAEICESTPVPASEKLPTYSATEAVDRYRGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWJ0</accession>
    <name>D3PWJ0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein 70</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3550</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018783.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3550"/>
    <dbReference type="EnsemblBacteria" id="ADD43212">
        <property type="protein sequence ID" value="ADD43212"/>
        <property type="gene ID" value="Snas_3550"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3550"/>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_457015_0_0_11"/>
    <dbReference type="OMA" id="NCAPITK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="372"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="381"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="632" mass="67589" checksum="92A051D6A8AAB4DA" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWL6</accession>
    <name>D3PWL6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3576</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3576"/>
    <dbReference type="EnsemblBacteria" id="ADD43238">
        <property type="protein sequence ID" value="ADD43238"/>
        <property type="gene ID" value="Snas_3576"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3576"/>
    <dbReference type="eggNOG" id="ENOG5033JSJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2248465_0_0_11"/>
    <dbReference type="OMA" id="FERRAMH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="104" mass="11602" checksum="933588382978CF20" modified="2010-04-20" version="1">MAMPTPSSAIGFHTQAQWITMLEQTLASAQRQRSARAGLDSCGVPEWVAFERRAMHEAVNRARVDRGLSPVTEAHVRWAEERAVGHGDYTRKFALYCADLISSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWV4</accession>
    <name>D3PWV4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Diaminopimelate decarboxylase</fullName>
            <shortName evidence="3">DAP decarboxylase</shortName>
            <shortName evidence="3">DAPDC</shortName>
            <ecNumber evidence="3 4">4.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lysA</name>
        <name evidence="7" type="ordered locus">Snas_5547</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:15101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="4.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.20" evidence="3 4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020749.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5547"/>
    <dbReference type="EnsemblBacteria" id="ADD45178">
        <property type="protein sequence ID" value="ADD45178"/>
        <property type="gene ID" value="Snas_5547"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5547"/>
    <dbReference type="eggNOG" id="COG0019">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026444_0_1_11"/>
    <dbReference type="OMA" id="YCRSMAS"/>
    <dbReference type="OrthoDB" id="861683at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06828">
        <property type="entry name" value="PLPDE_III_DapDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02120">
        <property type="entry name" value="LysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01048">
        <property type="entry name" value="lysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3 4" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="6">
        <location>
            <begin position="84"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="5">
        <location>
            <begin position="334"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="3">
        <location>
            <begin position="321"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="397"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="468" mass="49835" checksum="AED8259FE38B6785" modified="2010-04-20" version="1">MRVHEAGALHEEYTGGHGPAWLRMPVDVNDLIPQLWARTVNRDDAGVLTVGGVDVNKLAAEFGTAAYVVDEADFRSRLRDFRGSFSANFPDGAVYYAGKSFLCKAVARWVAEEGVNLDICTGGELATAVAAGFPGERLAFHGNNKSEAELAAALDAGVGTIVLDSRIEVERLTRLAKQRGVRPGVMVRTKVGVEAHTHEYIATAHEDQKFGLSLEAAVKAAKHILAADVLHLKGLHSHIGSQIFETTAFEVAARRVIGAHEQIQRETGKTLPELGLGGGFGIAYTTQDDPQSPRQLADGLRKIVDHECDNLGIDIPSITVEPGRAISGPTTFTLYEVGTVKSVDLGAGRVRSYVSVDGGMSDNIRTAMYGATYSVTLASRLSDAPPILGRVVGKHCEAGDIIVRDEFLPGDIKPGDLIAVPGTGAYCRSMASNYNHVPRPPVVAVADGTARLIVRGESVDDLLNLDVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWY6</accession>
    <name>D3PWY6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YbaK/prolyl-tRNA synthetase associated region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020781.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5579"/>
    <dbReference type="EnsemblBacteria" id="ADD45210">
        <property type="protein sequence ID" value="ADD45210"/>
        <property type="gene ID" value="Snas_5579"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5579"/>
    <dbReference type="eggNOG" id="COG2606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094875_1_2_11"/>
    <dbReference type="OMA" id="DRQISWP"/>
    <dbReference type="OrthoDB" id="1503081at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="1">
        <location>
            <begin position="30"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="159" mass="16920" checksum="1B86199A1E2B5C3E" modified="2010-04-20" version="1">MNATPLPDAVRAMVADGEAHGVDVEVRVRPAANSLPEAAEILGLTPADLAKTLVVRKTSDSYLFAIVPGDRSIAWPKLRELLGTNRLSMPDAATALAATGYERGTITPIGSHRPWPIYVDSRLRGRRVAMGAGAHGFSAFVDVDRLVDGYDAVLADITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX76</accession>
    <name>D3PX76_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1636</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016910.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1636"/>
    <dbReference type="EnsemblBacteria" id="ADD41339">
        <property type="protein sequence ID" value="ADD41339"/>
        <property type="gene ID" value="Snas_1636"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1636"/>
    <dbReference type="eggNOG" id="COG1141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_6_0_11"/>
    <dbReference type="OMA" id="MGRCAAT"/>
    <dbReference type="OrthoDB" id="1873445at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001080">
        <property type="entry name" value="3Fe4S_ferredoxin"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00352">
        <property type="entry name" value="3FE4SFRDOXIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 4" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="66" mass="7145" checksum="B42EC4AD65C0BC72" modified="2010-04-20" version="1">MRISVDTERCVAAGTCVLAAAEVFDQRDEDGIVVLLDESPPERLRAEVEDAVTVCPAAAITLREEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXP6</accession>
    <name>D3PXP6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerophosphoryl diester phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3719</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018947.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3719"/>
    <dbReference type="EnsemblBacteria" id="ADD43376">
        <property type="protein sequence ID" value="ADD43376"/>
        <property type="gene ID" value="Snas_3719"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3719"/>
    <dbReference type="eggNOG" id="COG0584">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030006_3_1_11"/>
    <dbReference type="OrthoDB" id="1542724at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048453" evidence="1">
        <location>
            <begin position="25"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="2">
        <location>
            <begin position="41"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="293" mass="31382" checksum="E102DE2D421A137E" modified="2010-04-20" version="1">MSWRRRVVGIGCVGAVLVTGSATATVSTQAYTPPKSCLESVTVFADGGKTATAPDMTAAAMSQAVARKGTWLSADVRLTADGVPVLVRDANLRRTTNVAEVFPKRADDNVDTFTLAELERLDAGTWFGDGYRGQKLLTMRDLLDYASVESGIGLSLAPRDLATTPGLAEAVDNEFRADERWEELFDARLVQLRSSEAEAMSDLARWVPEASIQWETASVPGEEELAEAQTWADSIGVDFNEVGGEDAERIHDAGLRLAWHAVDSPTAMADAINGGADEVFTVDPTIADAVCKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY28</accession>
    <name>D3PY28_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5727</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020928.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5727"/>
    <dbReference type="EnsemblBacteria" id="ADD45357">
        <property type="protein sequence ID" value="ADD45357"/>
        <property type="gene ID" value="Snas_5727"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5727"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_0_2_11"/>
    <dbReference type="OMA" id="RGRDAQW"/>
    <dbReference type="OrthoDB" id="1617768at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="111" mass="12265" checksum="DBC139185E4E2C9C" modified="2010-04-20" version="1">MVASDTLDATFAALADPTRRAILARLANGDATVTELAEPLTISQPAVSKHLRVLERAGLVSRGRDAQRRPCRLEAEPLRAATDWLADYRNYWEASYQRLDGLLDELRGGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYG7</accession>
    <name>D3PYG7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1838"/>
    <dbReference type="EnsemblBacteria" id="ADD41534">
        <property type="protein sequence ID" value="ADD41534"/>
        <property type="gene ID" value="Snas_1838"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1838"/>
    <dbReference type="eggNOG" id="ENOG50331I5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122300_1_0_11"/>
    <dbReference type="OMA" id="FDCSLRW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019675">
        <property type="entry name" value="DUF2550"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10739">
        <property type="entry name" value="DUF2550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="146" mass="16063" checksum="F6EFC846CBF89E35" modified="2010-04-20" version="1">MIETISAIAAIPVLAGLALALLFVRRSFLTKGGAIAMAVRIYQRVPGRGWAPGFAKFNSGRLSWYRMFSYAVRPRLTLDRADLKVEQRREPVGAERQVFPSSVVILCCKAPDEQVEIAMTRSALNGFLSWLEAAPPGAASDFFDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYI0</accession>
    <name>D3PYI0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Germane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1851</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017118.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1851"/>
    <dbReference type="EnsemblBacteria" id="ADD41547">
        <property type="protein sequence ID" value="ADD41547"/>
        <property type="gene ID" value="Snas_1851"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1851"/>
    <dbReference type="eggNOG" id="COG5401">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_463000_0_0_11"/>
    <dbReference type="OMA" id="WEVNLDM"/>
    <dbReference type="OrthoDB" id="796522at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019606">
        <property type="entry name" value="GerMN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10646">
        <property type="entry name" value="Germane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0564">Palmitate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049360" description="Germane domain-containing protein" evidence="4">
        <location>
            <begin position="28"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="Germane" evidence="5">
        <location>
            <begin position="184"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="587" mass="63369" checksum="7AB515EA4E092A62" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYL0</accession>
    <name>D3PYL0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3786</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019014.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3786"/>
    <dbReference type="EnsemblBacteria" id="ADD43443">
        <property type="protein sequence ID" value="ADD43443"/>
        <property type="gene ID" value="Snas_3786"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3786"/>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_0_3_11"/>
    <dbReference type="OMA" id="GSWGTNI"/>
    <dbReference type="OrthoDB" id="1942521at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048696" evidence="1">
        <location>
            <begin position="27"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="51"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="34597" checksum="71642DB1F834CFF6" modified="2010-04-20" version="1">MRKNWRLLGAVAIACALVTAGCGSSGDDAAGKTRVVKADNGKITIPENPKRVVATGYAVPALIEADAPLVGISTWKRGVPMMSKSEKATYDKLDKVAGEAAAETNYEAIAEAKPDLIVIGVPKPVLADVDLKRLEEVAPVVAIGPTVPSAWRDLSQRQADAAGALKGFNAAKGDYEDKAKELSEKYGDVLPDVKLAHVGAYGEIDKGTFQREFDDSWGTNVANDIGATYYGEVKEKGGGSKDVSEYPSIEELPEALGDAEAITYSVGPDGEPLKSVKYVLGSKLWKNLPAVKAGKTFPIRYTEAATYGDALLALDALDESLAPLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYW8</accession>
    <name>D3PYW8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019122.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3896"/>
    <dbReference type="EnsemblBacteria" id="ADD43551">
        <property type="protein sequence ID" value="ADD43551"/>
        <property type="gene ID" value="Snas_3896"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3896"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096119_0_0_11"/>
    <dbReference type="OMA" id="RCWLLTS"/>
    <dbReference type="OrthoDB" id="1983082at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="184" mass="20228" checksum="440BAFB1750DAE83" modified="2010-04-20" version="1">MRYDGTAILDIADEISGTYAEIFSQPPWNKAHDSDPDVVMRGFRTRLDKDMERPGFRVVVARSAAGIDGFASGWVTPSPYPDNRAYGKVSDSIGAEAVAELLVGAIEVDELAVRERARGKGLARRLLADLTADAPEGRAWLLTWTGAPEAVEFYERLGWYRVPVVPGRENDIVTFLAPTHPRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ96</accession>
    <name>D3PZ96_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017141.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1874"/>
    <dbReference type="EnsemblBacteria" id="ADD41570">
        <property type="protein sequence ID" value="ADD41570"/>
        <property type="gene ID" value="Snas_1874"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1874"/>
    <dbReference type="eggNOG" id="COG5006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057295_0_0_11"/>
    <dbReference type="OMA" id="GMNVAFY"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="290" mass="29862" checksum="E7EF230EE5EA8042" modified="2010-04-20" version="1">MGLGVEAATRNWTDRVPVPAFLGASAFFHYFGPSIAVLLFAFVDVMGVAWLRIASAAVVLAVWRRPWRLVRVLGARQWVGLVGLGVVLAAMNSTFYLAIERLPLSTVGAIEFLGVIGVAAFGVRDRRNLAALVLAVGGVAALVEVRVVDAPLGFGFAFANCVLFVGYVVVGHRVANAGGIGVADRLAVAMVVAAVVATPFGVGEAVPALLDPGLLGAGVAAGVCSSVIPYLCDQVVMARVSRPSFATMLCLLPASATVVGLVVLVQWPSVVELLGVGLVVVGVALHRPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZA3</accession>
    <name>D3PZA3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017148.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1881"/>
    <dbReference type="EnsemblBacteria" id="ADD41577">
        <property type="protein sequence ID" value="ADD41577"/>
        <property type="gene ID" value="Snas_1881"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1881"/>
    <dbReference type="eggNOG" id="COG2194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068015_0_0_11"/>
    <dbReference type="OrthoDB" id="2054990at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="266" mass="29107" checksum="F1AAFCEA95E5C015" modified="2010-04-20" version="1">MTEPNGRLVKRVLRDRDGIWRQIAEDRGLRTLSGRMLFSSTVSFVAYGAVLGASNGVPQAISSAVKLPLLFLGTMFICLPTLYLFNLIRGVRLSFRQAQALVITAITAIAMLSLAFLPIVLFFLVVAPDYEFYKMLNVIILTVATLVGLRFLVSGMRKLNMIAKERAAEAATVGASSVAESGMDADGTEIAPVRGSPVYLRGKPAPRTGSVSLLYAWIVVFAFVGTQLAWTLRPFIGNPAEPFQVFRTYEGNIYVDIFRTIGQLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZS5</accession>
    <name>D3PZS5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019183.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3960"/>
    <dbReference type="EnsemblBacteria" id="ADD43612">
        <property type="protein sequence ID" value="ADD43612"/>
        <property type="gene ID" value="Snas_3960"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3960"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_2_2_11"/>
    <dbReference type="OMA" id="KNGWVRR"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="18937" checksum="41E96DD3F6519F2D" modified="2010-04-20" version="1">MSGPWLDDVEQSTWRAFLWSTQLFHEALDRQLQRDSGIPHTYYMILAMLSESSQRTRTMTELAAATRFSPSRLSHAVSRLEKNGWIKRKRHPHHGRSIVAELTDEGFAALREAAVGHVAEVRKLLFDPLTSDEQEQLRGLCEKILVGLPNTRGCAAEPETGEGADAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZU6</accession>
    <name>D3PZU6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019204.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3981"/>
    <dbReference type="EnsemblBacteria" id="ADD43633">
        <property type="protein sequence ID" value="ADD43633"/>
        <property type="gene ID" value="Snas_3981"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3981"/>
    <dbReference type="HOGENOM" id="CLU_2958564_0_0_11"/>
    <dbReference type="OrthoDB" id="1920995at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="59" mass="6470" checksum="19E198AA0FFE350C" modified="2010-04-20" version="1">MSNADPQSLRTLCLTCSGSGDLERQAARVKDGKIVAGVVSDECWFCRGEGWLHFARRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q046</accession>
    <name>D3Q046_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021146.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5948"/>
    <dbReference type="EnsemblBacteria" id="ADD45575">
        <property type="protein sequence ID" value="ADD45575"/>
        <property type="gene ID" value="Snas_5948"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5948"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093811_0_0_11"/>
    <dbReference type="OMA" id="QWVRSAR"/>
    <dbReference type="OrthoDB" id="1389691at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="129"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="259" mass="27291" checksum="5E4FE4C64B30F62F" modified="2010-04-20" version="1">MGELEIATVAAADDAWVGAPTGSQIVETAEFRIARLPERFPDPLQVQWVRSARPAATVLTEIVERATGFGLPETVVCVKPSAPADLDEALLARGAELVDTADVLAMPLPAEFRATDLPGLEVRWRTTPKIGRDANTVGIATFGGTRAPDVDVALQAASDRETVAAGFGGAVVAYLDDTPVAVAGLEVADDVARLWGGGVLEAHRGLGVYRALVATRLSYAAEHGATMALTKGRVSTSSPILRRLGFVSYGQERTYRLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0U8</accession>
    <name>D3Q0U8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4046"/>
    <dbReference type="EnsemblBacteria" id="ADD43698">
        <property type="protein sequence ID" value="ADD43698"/>
        <property type="gene ID" value="Snas_4046"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4046"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_59_0_11"/>
    <dbReference type="OMA" id="TTHWKSA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="222"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="36158" checksum="6AF5B30007A630C8" modified="2010-04-20" version="1">MSGFTTQRHRVAVLVRAGVLPMELGIVHELFGGARSATGEPLYEVLTCTREPGVVTTNTEFTINVAHDITILGAADTIVVPAADADHQLSPTVEPWLVEALRRVSPETRIASICTGAFVLAAAGLLDGRRATTHWNCVDCFQRMYPDIDVDPDVLYVDQGRILTAAGEASGIDLCLHMIRCDHGSAVAGEVARRTVVPPHREGGQAQYIRRPVPEPRQSSTKNARDWALRHLHRPLTLRELAARESMSPRNFTRRFRQEMGISPGQWLSNQRLDRARQLLEETDTPVDRIAREAGFGTGTSLRQHFRTVLGVSPRAYRQTFRGTTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0X3</accession>
    <name>D3Q0X3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribose 5-phosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LacAB/RpiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019294.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4071"/>
    <dbReference type="EnsemblBacteria" id="ADD43723">
        <property type="protein sequence ID" value="ADD43723"/>
        <property type="gene ID" value="Snas_4071"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4071"/>
    <dbReference type="eggNOG" id="COG0698">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091396_1_0_11"/>
    <dbReference type="OMA" id="QKMEFKK"/>
    <dbReference type="OrthoDB" id="1346802at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016861">
        <property type="term" value="F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003500">
        <property type="entry name" value="RpiB_LacA_LacB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036569">
        <property type="entry name" value="RpiB_LacA_LacB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02502">
        <property type="entry name" value="LacAB_rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005384">
        <property type="entry name" value="RpiB_LacA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89623">
        <property type="entry name" value="SSF89623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00689">
        <property type="entry name" value="rpiB_lacA_lacB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="156" mass="16626" checksum="082628D1D102C8BF" modified="2010-04-20" version="1">MSSRQWRIAVGADEAGFQYKEAIARDLAEDSRVGSVVDFGVAEGETTPYASVGLTVAEAVARGEVDRAILICGTGIGMAISANKVPGVRATTVSDSYSCERSVLSNDCQIISFGQRVVGLELARRLASEWLGYEFDPASPSNSKVSVISAYERRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q100</accession>
    <name>D3Q100_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">3''-kinase</fullName>
            <ecNumber evidence="7">2.7.1.87</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4099</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the aminoglycoside phosphotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.87" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019321.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4099"/>
    <dbReference type="EnsemblBacteria" id="ADD43750">
        <property type="protein sequence ID" value="ADD43750"/>
        <property type="gene ID" value="Snas_4099"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4099"/>
    <dbReference type="eggNOG" id="COG3231">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073027_0_0_11"/>
    <dbReference type="OMA" id="RYAKCVP"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050299">
        <property type="term" value="F:streptomycin 3''-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05150">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024165">
        <property type="entry name" value="Kan/Strep_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000706">
        <property type="entry name" value="Kanamycin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="6">
        <location>
            <begin position="27"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000706-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000706-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="273" mass="29865" checksum="A993184B76D99055" modified="2010-04-20" version="1">MIDPPEAWTASSVLLGVDEGAWLPITTGQSGAAVFRSADGTRFAKCVPAADAAELQDERDRTTWLNDQGVPGPRVLDWRSGEAGACLVTTAVSGVPADQVSSEDLRRAWGSIADALRQLHELPVSQCPFRWGLDSMVALARDVVARDAVNPEFLPVEQRGTPAAELLERIVAQVPQRREQEAADTVVCHGDLCLPNIILDPETLDVAGFIDLGRLGLADRYIDVALLLTNARENWTDEEQARTADVAFAEKYGIDLDHDRLRFYLHLDPLTWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q159</accession>
    <name>D3Q159_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6014"/>
    <dbReference type="EnsemblBacteria" id="ADD45639">
        <property type="protein sequence ID" value="ADD45639"/>
        <property type="gene ID" value="Snas_6014"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6014"/>
    <dbReference type="eggNOG" id="ENOG5031X7M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1634363_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048151" evidence="2">
        <location>
            <begin position="31"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="162" mass="16971" checksum="9CF98FB0E82C0DDE" modified="2010-04-20" version="1">MTSSVDLSPRFRVRAAAVLLLVTAVFIAVAWSQLFFGAGNDPRDTIGSRAAGFGFTDHAHDTLYSAIPLALPLVAALSTTHGGVRLVAVVEYGVLIVTGALITGAAFVFGLDVAEQQRAGFDTVFVDTRSAVEALLLDLGLLTLVVVAMLGCLRAWLRGRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1B6</accession>
    <name>D3Q1B6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6072"/>
    <dbReference type="EnsemblBacteria" id="ADD45696">
        <property type="protein sequence ID" value="ADD45696"/>
        <property type="gene ID" value="Snas_6072"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6072"/>
    <dbReference type="eggNOG" id="COG5164">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_595673_0_0_11"/>
    <dbReference type="OMA" id="PQCRGDK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="366"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="459" mass="46376" checksum="AC666BE59E823519" modified="2010-04-20" version="1">MTSDPNNPSAPQSGPPAQQSSGDEDNTSVIRPAQESAPPSAEQAHAEAPTAENPAAHQPQSPAPQPEDNGTAKLGQPPAQPQQPEEDPGTSKLGGPPQQQPPAQPQQQQAPQWPQMPPPAHQPPPAPDSDSTQQIPQVAPPQPPPAPPAPPAPSQDNTSVLPTQQPPQPPQAPPQPPQAAPQPPPPAPPQPPVGPDSTAALPAQTPPGQMPPPPPVAPPQPPPMAPPQPPQYQPPPQQYGAPPPPMGSPAAMPGSPSAMPGSPQVSQQPGMPSPPSSAPPANQSGLQPGMPLWGGSQPGATAQQPAAMPGSPVAGSPWQPSDPGAPQPVTGPPAGQPGQPDFGGGFPPGGGVPGMPGGEQPKKKNLGLLIGVGVAAIILIAGLAFGGIMLFGGEKFEQGGCVKQEGSEAVAVSCDDKDAKYKITKQVKKSSECKDQTMPVVKLEDEGIVYCLEAADKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1P6</accession>
    <name>D3Q1P6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015465.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0174"/>
    <dbReference type="EnsemblBacteria" id="ADD39894">
        <property type="protein sequence ID" value="ADD39894"/>
        <property type="gene ID" value="Snas_0174"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0174"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_3_11"/>
    <dbReference type="OMA" id="IGHIRIT"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="406" mass="42977" checksum="C97819C2B2FE3F39" modified="2010-04-20" version="1">MTAMRPSGRFPAQAANTPGHLLNLIRSRDNWTRQQLLTATGLSRTTLFSRLGQLFRSGYAYESGAARSTGGRPSSLVRFEDRGRVVLVIDLGHRHGRIAITTVGGTTLRETRLSIDIAQPPKTLLPTIYDQAQHLLDTGTDEKLVGVGVAVPGPVSPVTGHLTETTIMPGWHHYPLNAEMADRWGVPVLLENDARAYALGESVERPDASPLVAVKYANGIGAGIVLDGQLLCGVGGAAGDIGHIRITDARGRRCRCGRNGCLAAYASGHALLRQLRRPTDTTVDDLATTMATHQPTETAVRAAATLLGRTLASLVATLNPQLIVLGGVLGRTPAVVEEVRSQIHTLAIDRVTTPLSVTASTAHHPVGTGLTALVTGHVYAPDNVDATLTAQPTTADTRSTPPHRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q219</accession>
    <name>D3Q219_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tyrosine recombinase XerC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">xerC</name>
        <name evidence="13" type="ordered locus">Snas_2194</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the 'phage' integrase family. XerC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017457.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2194"/>
    <dbReference type="EnsemblBacteria" id="ADD41886">
        <property type="protein sequence ID" value="ADD41886"/>
        <property type="gene ID" value="Snas_2194"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2194"/>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_9_0_11"/>
    <dbReference type="OMA" id="QAFWYLI"/>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 9" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0229">DNA integration</keyword>
    <keyword evidence="7 9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="12">
        <location>
            <begin position="21"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="11">
        <location>
            <begin position="128"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="9">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD41886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="317" mass="34012" checksum="95D383330B0E5EB5" modified="2010-04-20" version="1">MARSETEAADADDSQYEALPASFKEVLGQFVHHLTHECGRSAHTVRGYRADVTSLLVHLAATGTTRLAGVDIAGLRSWLANRRAQGIARASLARKVSAVRAFTAWAHRQGHLDADAGARLSGPSVPHNPPEILRTDQAETLAAATASDGSATGLRDRAVVELLYATGIRVSELCGLDVASVDRSRNVLRVFGKGAKERTVPFGIPAARAVDDYLQRARPELAADHSGDALLLGVRGGRLHPSTVRRVLRDWLSRTGMPSLTPHGLRHSAATHLLDGGADLRSVQELLGHASIDSTQIYTHVSAERLRGAYRQAHPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2D9</accession>
    <name>D3Q2D9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019443.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4223"/>
    <dbReference type="EnsemblBacteria" id="ADD43872">
        <property type="protein sequence ID" value="ADD43872"/>
        <property type="gene ID" value="Snas_4223"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4223"/>
    <dbReference type="eggNOG" id="ENOG502Z7TR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037838_3_0_11"/>
    <dbReference type="OMA" id="VCPVVRY"/>
    <dbReference type="OrthoDB" id="933146at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021145">
        <property type="entry name" value="Portal_protein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05133">
        <property type="entry name" value="Phage_prot_Gp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="470" mass="50986" checksum="2273A156A6C3C154" modified="2010-04-20" version="1">MPTPTDTAVELLARLSDETERLDRIDKYLRGEHDGPYTPRKASREYKILAQRSVTNLLPLVVNGLAQSLYVDGYRSGDTDEPASAWRHWQHNGLDARQSAIHRAALSYGRAYVVVVPGKDAEGAEAVPTVRGYSPRRMIAAYADDDDEWPEYAVRWASATVEGKSGRRVWFYDDETVHVFTSTSADGGDLAPEDSYEHGAGVTPVVEFRHLPDLEGRALGEVEPLIALQDRANQSTFDLLVAQTFSSFKIRTVSGMAPKFDDDGNPVPLPVDAARLLMATDPDTKFSQLDETDLRPLLDSIDAAVRHMAVVSQTPPSDLLGQLVNLSAEAITAARDGANRRRAETQAVFGECWEKVLRLCELVLGGDADTSAQVSWRDMEGRSLAQIADALGKLAQTLEVPVEALWPRIPGVTQTDIEAWQRMRATDRAADPLSKLADHVNQTAGGDGGLDNVINAADVAASAATGAASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2H6</accession>
    <name>D3Q2H6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CinA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4260"/>
    <dbReference type="EnsemblBacteria" id="ADD43909">
        <property type="protein sequence ID" value="ADD43909"/>
        <property type="gene ID" value="Snas_4260"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4260"/>
    <dbReference type="eggNOG" id="COG1546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030805_1_0_11"/>
    <dbReference type="OMA" id="VEHALNM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036653">
        <property type="entry name" value="CinA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008136">
        <property type="entry name" value="CinA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02464">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142433">
        <property type="entry name" value="SSF142433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00199">
        <property type="entry name" value="PncC_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="CinA" evidence="2">
        <location>
            <begin position="6"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="16831" checksum="90C46E7CBCA14009" modified="2010-04-20" version="1">MTTVTAADIVAALKRRGQHLACAESLTGGLFAAAVTAAPGASAVFTAGIVAYTPRMKTELLGVPAEVIDSAGVVSREVAAALALGARDRTGADWGVGTTGAAGPEAHGGQPPGTVWIAVADPSGEVTARKLALSGGRAEVCRATVEAAKGLLMERLDPRGREFVTPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2N2</accession>
    <name>D3Q2N2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021354.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6160"/>
    <dbReference type="EnsemblBacteria" id="ADD45783">
        <property type="protein sequence ID" value="ADD45783"/>
        <property type="gene ID" value="Snas_6160"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6160"/>
    <dbReference type="eggNOG" id="ENOG5030GT7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150704_0_0_11"/>
    <dbReference type="OMA" id="MLEGYPC"/>
    <dbReference type="OrthoDB" id="1670892at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="15597" checksum="7EA5931BDC930204" modified="2010-04-20" version="1">MSLSHIVLSSGRSIGLTELRMSATYGATLEGYPCQRINNMQVSSLLRQANHAFSFAPVHLVPPSREYPDQTAGAFGPVEVLPSVACIGVFGSTPIDPELDPVLHRSALIVAWFQATPDVPSGEHVDPALRNIRWEELAQDYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2T6</accession>
    <name>D3Q2T6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase</fullName>
            <ecNumber evidence="2">2.7.6.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_6216</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021408.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6216"/>
    <dbReference type="EnsemblBacteria" id="ADD45837">
        <property type="protein sequence ID" value="ADD45837"/>
        <property type="gene ID" value="Snas_6216"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6216"/>
    <dbReference type="eggNOG" id="COG0801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097916_0_0_11"/>
    <dbReference type="OMA" id="QVILRQN"/>
    <dbReference type="OrthoDB" id="1953248at2"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPPK" evidence="8">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="169" mass="18362" checksum="24A27BBABE627364" modified="2010-04-20" version="1">MTTVVLSLGANLGDRRAALASAAEALGPGQLSEVYETPPWGDDDQPTYLNLAMIATDADRSVEDWLALAEDIQAKAGRVRDPKRRYGPRVLDVDIIMAWDADGEPIHCDSPTLTLPHPRAHLRAFVLVPWLSLQPDAALPGRGRLRDLLRDPGLAADARALRRVGKLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2W2</accession>
    <name>D3Q2W2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6242</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021434.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45863">
        <property type="protein sequence ID" value="ADD45863"/>
        <property type="gene ID" value="Snas_6242"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6242"/>
    <dbReference type="eggNOG" id="COG4710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2059990_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="119" mass="13053" checksum="B7EB5C72C55A1F53" modified="2010-04-20" version="1">MTDNERPERLPSTAAETQEVMDRLEFDAPPSTPAEEAELLAQLPPAGSPIMTVRSLRMPIELAERVSKAAEKAGIPKTAWIRQAIEAQLAEEEEDTRVVSLADVRRALSLVRPAQDHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q309</accession>
    <name>D3Q309_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)H quinone oxidoreductase, PIG3 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015550.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0261"/>
    <dbReference type="EnsemblBacteria" id="ADD39979">
        <property type="protein sequence ID" value="ADD39979"/>
        <property type="gene ID" value="Snas_0261"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0261"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_4_11"/>
    <dbReference type="OMA" id="VWSNVFM"/>
    <dbReference type="OrthoDB" id="1027479at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05276">
        <property type="entry name" value="p53_inducible_oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014189">
        <property type="entry name" value="Quinone_OxRdtase_PIG3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02824">
        <property type="entry name" value="quinone_pig3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="324" mass="33539" checksum="40E2F2C91B481B90" modified="2010-04-20" version="1">MRAVEIAEPGGPEALKVIDAPDPIPGSGEVVIEVAAAGINRADAAQRRGKYPPPEGASPYPGLEVSGRIIAIGPGVAGVSVGDEVCALLSGGGYAERVAVDARLLLPIPDGVDLVDAAGLPEVAATVWSNVFQIARLTEGEMLLVHGGSGGIGTFAIQLATARGCGVLTTARSHNADALRGLGAELVIDYRDQDFAEEVATHTDGRGVDVILDHLGASYLDRNVASLNLNGRLAIISMQGGSKTEFNLGALMRRRGSVSATTLRSRPIGERADIIAAVRDNVWPQVASGQVKPVVAQRFPLADVVEAHRVLDAGGYLGKILLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q343</accession>
    <name>D3Q343_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0295</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0295"/>
    <dbReference type="MEROPS" id="S54.A08"/>
    <dbReference type="EnsemblBacteria" id="ADD40013">
        <property type="protein sequence ID" value="ADD40013"/>
        <property type="gene ID" value="Snas_0295"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0295"/>
    <dbReference type="eggNOG" id="COG0705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055068_2_1_11"/>
    <dbReference type="OMA" id="PICPECM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="134"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="317" mass="33749" checksum="0DC288B33CC8C8C0" modified="2010-04-20" version="1">MDDNPNAPVCYRHPQKETYVRCARCDRPICPDCMNQASVGFQCPECVREGQKSVRRPRTALGAVGGSGMVTKTLVGINVAVFLLGLVWAASLGGVGNVLGGDTTPLHYLGSLWAPPYSDIVVEGLGIKVSGVAGGAYYRLLTSMFLHYGVIHLLFNMYVLWVIGQYLERELGPLRYLGLYLLSGLGGNVLTYLLADTGASITNANSWAWTAGASGCIFGLFGAMVLINRKLGRDMSGVYVILGLNLVITFLPGTNISWTGHIGGLLTGLALGAALAYAPRANRAMIQTVAFVGVLVVFVGLIAWRTSTLNTLLSSIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q390</accession>
    <name>D3Q390_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0342"/>
    <dbReference type="EnsemblBacteria" id="ADD40060">
        <property type="protein sequence ID" value="ADD40060"/>
        <property type="gene ID" value="Snas_0342"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0342"/>
    <dbReference type="HOGENOM" id="CLU_2703051_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="73" mass="8596" checksum="9697841918976340" modified="2010-04-20" version="1">MTRINDKGEQHMQRENAAKNARRNLDRAERDNLDTNQRIQLGFAWTLLSIAEEMNRRTQVQAKIHDIDGFDKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3G1</accession>
    <name>D3Q3G1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017573.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2315"/>
    <dbReference type="EnsemblBacteria" id="ADD42002">
        <property type="protein sequence ID" value="ADD42002"/>
        <property type="gene ID" value="Snas_2315"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2315"/>
    <dbReference type="eggNOG" id="ENOG50338IC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149376_1_0_11"/>
    <dbReference type="OMA" id="RILMFIW"/>
    <dbReference type="OrthoDB" id="2089363at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021214">
        <property type="entry name" value="DUF2568"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10823">
        <property type="entry name" value="DUF2568"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="112" mass="11899" checksum="07813BC3E1C467E4" modified="2010-04-20" version="1">MRALENANSLLMFLLELGVLAAVGYWGLTLATSLWLRILVAVGGIAVFVTVWALFGAAADATYPAEGIWRAALEIGWFGGGATALALAGRTTLAVIFAVLFIINAALRLYWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3M0</accession>
    <name>D3Q3M0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017632.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2376"/>
    <dbReference type="EnsemblBacteria" id="ADD42061">
        <property type="protein sequence ID" value="ADD42061"/>
        <property type="gene ID" value="Snas_2376"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2376"/>
    <dbReference type="eggNOG" id="ENOG50318Z2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158543_0_0_11"/>
    <dbReference type="OrthoDB" id="2018772at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="99" mass="11573" checksum="44BDF61583029AB6" modified="2010-04-20" version="1">MFRRWVHVREEDEPETRTYRPYDYPIPPGRGRDGIAFRLDGTVTRYDSGPTDAPVGVTGRWSLRDDDVLQLNFPDRSLATRYRLVAVEPERLRLAPLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3X0</accession>
    <name>D3Q3X0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase III, epsilon subunit</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019608.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4390"/>
    <dbReference type="EnsemblBacteria" id="ADD44037">
        <property type="protein sequence ID" value="ADD44037"/>
        <property type="gene ID" value="Snas_4390"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4390"/>
    <dbReference type="eggNOG" id="COG0322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022933_0_0_11"/>
    <dbReference type="OMA" id="AVDHVEC"/>
    <dbReference type="OrthoDB" id="1985371at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006054">
        <property type="entry name" value="DnaQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00573">
        <property type="entry name" value="dnaq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="226"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="578" mass="62446" checksum="D626951647EFBE9A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3X4</accession>
    <name>D3Q3X4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4394</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019612.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4394"/>
    <dbReference type="EnsemblBacteria" id="ADD44041">
        <property type="protein sequence ID" value="ADD44041"/>
        <property type="gene ID" value="Snas_4394"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4394"/>
    <dbReference type="HOGENOM" id="CLU_876917_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="163"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="317" mass="33025" checksum="4468286EB9F12C49" modified="2010-04-20" version="1">MDDRPIDPFNPYARRYSPPPPTWPEQHPSTPAPDDTQEVPVVPPAHEVPPAPVNPAASASMDDTQEVPVIPPQPAAPPPEWPVTAQPEPTALVPPGQPSPPGQPTAPVSAPAAPFGPELTVPPDLVTRKKPGPRKAPLIAVGASVLGLLVLVTVAIFAFQPGTADGSQDKAEASSDTPDSSGDASSSSPEESKSPSKNPKPETEKSSDAEPGGEPEDDGGEDNAEPELSVPSRPTKFGAWFAGNGTYQAKWGPPSSDGNADILSYVIGDCKGNNLAFVDSNTYKATVQADYLECMSVYAVNNQGMGQDAQHQITNNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q407</accession>
    <name>D3Q407_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6272</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6272"/>
    <dbReference type="EnsemblBacteria" id="ADD45892">
        <property type="protein sequence ID" value="ADD45892"/>
        <property type="gene ID" value="Snas_6272"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6272"/>
    <dbReference type="eggNOG" id="ENOG502Z8JQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072779_0_0_11"/>
    <dbReference type="OMA" id="YWFIDIS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031009">
        <property type="entry name" value="Tcm_partner"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04474">
        <property type="entry name" value="tcm_partner"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="339" mass="39355" checksum="919EA28C86F1E57E" modified="2010-04-20" version="1">MERLWGWWTQHKLEILGEYLQAFATATKNKSKSRIYFDLFAGVPKNRAKLTNEEIVGSAQRALTTDPPFTHVALFELAPKAQLLRNALAQQFPRHTGVRVYDGDCNVQIDRALGDFAHVRWAPAFAFVDQHDNEIRWETLTKLARFRRTMRRVPTKTELWILLGTSFNVRTLLRKDGRANGEYADSLTRMFGDDSWRPIVEARRDELISATMFRAEWVNLMRWRLERVLGYGITYAFTMKETGGKDLYDMVFASDHQAGQKIMAHLYGKAAARHEQMRQHALRIRRDQSLQKKDGTVGLFALTTDMVVVDVPNKELYVHDQPHEPRDLTYYRSHGDQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q410</accession>
    <name>D3Q410_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TAP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021466.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6275"/>
    <dbReference type="EnsemblBacteria" id="ADD45895">
        <property type="protein sequence ID" value="ADD45895"/>
        <property type="gene ID" value="Snas_6275"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6275"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_3_1_11"/>
    <dbReference type="OMA" id="AIMCSDT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049685" evidence="1">
        <location>
            <begin position="28"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="79"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="476" mass="51273" checksum="715350599E053581" modified="2010-04-20" version="1">MKRKLVLISALTAVLAAAVVYSANAGATTSEVNWKPCGDKPGAECGTLEVPRDWDDPDSKTVTLNLSRRVATDPDKRVGVLFYNPGGPGQGAADLVRDYAEQKFSPRLRERFDIVGIDPRGVAGSQAVKCDKPVNDPKVSLFPDNEDEYRKLLAHNKEVADSCDDLIADVGTDNVAQDFDAVRSALGEDSITYFGQSYGSMLGTAYAQRFPQRVRAMSLDGVVDHGMPSEQMVSEASSAVEESFESFADWCAKNEKCALHGRDVGEVWDATVAKAEAEPIPVPGKRALTAEELRFAAYAMLNMVPEFGSELGKAIAAAEKGDGTAFAAIRAEAENPATSAAYRSILCMDIDPGVDGYDELRDRLADARKRSPHMGGTSEFWNMTAGCLNWPVPPSNPQGPIDIDGVPPTLLVGNTGDPATPVEWAESLSQGIEDSRVLTYDGTGHTAYLRSKCVTERVDDYLVDAKLPKPGEVCRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q420</accession>
    <name>D3Q420_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021476.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6285"/>
    <dbReference type="EnsemblBacteria" id="ADD45905">
        <property type="protein sequence ID" value="ADD45905"/>
        <property type="gene ID" value="Snas_6285"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6285"/>
    <dbReference type="eggNOG" id="COG1108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037853_0_0_11"/>
    <dbReference type="OMA" id="GAWTVDH"/>
    <dbReference type="OrthoDB" id="687646at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049521" evidence="2">
        <location>
            <begin position="30"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="379" mass="39883" checksum="1276721ECBBDBF0D" modified="2010-04-20" version="1">MRTPPPLLCAALAVILLGGCASGTDKPSADDKPHGYVEGAEETAEPQRRLVMAEAETGTLSQLDPATEKTAELADVKGVAGLVTDGRYVFAAGKDKTSIIDSGVWTVDHGDHKHYYVAEAKPVDTVDIDEAVSASADAAVSTVNTPDGAHVYDREQLADGKIAPVDTEAALAVPYAGELVTATDGRITVADKESDLDASCPRPTAAATTDRGAVFGCGERVVVVTEKDGTFSADELNAPAGIAAAQRFQHRPGTPVLVTAAKGEVTVFDVAEGDWSVIDAPDPVAVNATGEDMPVLVLDRDGTLRSFDQRTGDPIAERRVIDKMPKDGPAPVITVDTERAYVNDPEAKAVHEIDFQDELRLARSLTLDTRPDLMVETGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4B1</accession>
    <name>D3Q4B1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA methyltransferase, TrmH family, group 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0353</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015642.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0353"/>
    <dbReference type="EnsemblBacteria" id="ADD40071">
        <property type="protein sequence ID" value="ADD40071"/>
        <property type="gene ID" value="Snas_0353"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0353"/>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021322_0_0_11"/>
    <dbReference type="OMA" id="QVPPYEY"/>
    <dbReference type="OrthoDB" id="1422015at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429">
        <property type="entry name" value="PTHR46429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00186">
        <property type="entry name" value="rRNA_methyl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="2">
        <location>
            <begin position="97"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="339" mass="35636" checksum="E8C8618329119968" modified="2010-04-20" version="1">MPGNSQPRNKRVSSKKGATKGSGGQGKKSLAGRGKTLSAADRPWHKAYTGTDVPKKTKWKQEKERRAAAAEGRAPKAGRPKRPSTQSKRRDSDGVDVLVGRNPVVEALRAHVPGTALYVVNGTELDDRIRESIRLAGNRGISILEVSKSELDRLCQGALHQGLGLQVPPFHYEEYADVLAAAGEHPQPPLLVALDGVTDPRNLGATIRSAAAFGAHGVVVPQRRAAGMTATAWRASAGAAARLPIAKATNLTRAIQQAQQAGLLVAGLDADGEIDLFDLPAAVDPLMLVVGSEGRGLSRLVGESCDLRVRIPIASAVESLNAAVAASVALAEVTRRRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Q8</accession>
    <name>D3Q4Q8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Phosphatidylinositol phosphate synthase</fullName>
            <shortName evidence="10">PIP synthase</shortName>
            <ecNumber evidence="10">2.7.8.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">CDP-diacylglycerol--D-myo-inositol-3-phosphate 3-phosphatidyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Snas_2405</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 10">
            <text>1,2-di-(9Z-octadecenoyl)-sn-glycero-3-cytidine-5'-diphosphate + 1D-myo-inositol 3-phosphate = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61216"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:85356"/>
            <dbReference type="ChEBI" id="CHEBI:144472"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 10">
            <text>1D-myo-inositol 3-phosphate + a CDP-1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60504"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58088"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Contains a di-nuclear catalytic Mg(2+) center.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10 11">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.-" evidence="10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017659.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2405"/>
    <dbReference type="EnsemblBacteria" id="ADD42088">
        <property type="protein sequence ID" value="ADD42088"/>
        <property type="gene ID" value="Snas_2405"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2405"/>
    <dbReference type="eggNOG" id="COG0558">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080384_0_1_11"/>
    <dbReference type="OMA" id="DGNMARQ"/>
    <dbReference type="OrthoDB" id="1232102at2"/>
    <dbReference type="UniPathway" id="UPA00220"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02241">
        <property type="entry name" value="PIP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044268">
        <property type="entry name" value="PIP_synthase_PgsA1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="CDP-DAG binding" evidence="10">
        <location>
            <begin position="32"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>a CDP-1,2-diacyl-sn-glycerol</name>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>a CDP-1,2-diacyl-sn-glycerol</name>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD42088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="205" mass="21249" checksum="25E187049A227C7D" modified="2010-04-20" version="1">MAKFLSVSARAGVAKVLDPVGAWLVRHGISANTVTLVGTGAVVAGAAFLVTRGELLWGLVVITVSVFTDLLDGSMARTQGKPNRFGALLDSTMDRVADGAILGCLAYWLAVSGQPVSATACVISLVAAQTISYVKARAEGLGASCEVGVAERAERLIILGVGTLLWLFGVPYALAIALWILAAATVFTVGQRIWHVRGQLNGEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4S8</accession>
    <name>D3Q4S8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_2425</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017679.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2425"/>
    <dbReference type="EnsemblBacteria" id="ADD42108">
        <property type="protein sequence ID" value="ADD42108"/>
        <property type="gene ID" value="Snas_2425"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2425"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043648_0_0_11"/>
    <dbReference type="OMA" id="YCAAFEN"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014305">
        <property type="entry name" value="RNA_pol_sigma-G_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02960">
        <property type="entry name" value="SigX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="7">
        <location>
            <begin position="20"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="8">
        <location>
            <begin position="139"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="332" mass="36137" checksum="62D8493065B8611A" modified="2010-04-20" version="1">MTTDPARAESGPGDAAHRLEPYRRELLAHCYRMVGSADEAEDLVQETFLRAWRSRRDFEGRSSWRTWLYRIATNVCLTALEQRGRRALPSGLGAPAEDATTPPRPAEPGIAWLQPIPDAQVAPRSADPATVVTAREGLRLALIASLQYLPARQRAVLLLREVLAFPAAEVASMLDTTTAAVKSALQRARARLDDVDPKGEPLREPTEPRTRELLEQYITGFENADTAALERALRADAAIELVGTRTWFSGRATCLGYLRTVIGRCGDWRMLPTAANGQPAVAAYVRSADGIHRAFGIGVLTVSQEGISHVHVFGGGADLTATFGLPPVWPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4T8</accession>
    <name>D3Q4T8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GHMP kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2435"/>
    <dbReference type="EnsemblBacteria" id="ADD42118">
        <property type="protein sequence ID" value="ADD42118"/>
        <property type="gene ID" value="Snas_2435"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2435"/>
    <dbReference type="eggNOG" id="COG4542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056896_1_0_11"/>
    <dbReference type="OMA" id="VMFAESV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012363">
        <property type="entry name" value="PduX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF1">
        <property type="entry name" value="PTHR43527:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="1">
        <location>
            <begin position="123"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="332" mass="35261" checksum="7335C8BE452F80F4" modified="2010-04-20" version="1">MTSLMATCDVTDDARRAPFDTFPLHQPLVGRRFGHGQSIGHHGELLQGTFEDSDGLRHRALVTLPLPGLVTHAYFHPGPGAPGRVTVKPAWKRKAAAAAELILSRYLPTASGELVIHGAGAQPGLGLGSSTSDVTAALRAVADCYALPVTAADLARLAVEAEGASDSVMLDSQVVLFAHRCGHVLESFNRLLPHIVVVGCDTDPDRGGVDTLGFRPPEHTAAEIGEFRCLLGLLRHGLSTGSVSLLAKVAEASARINQRYLPTREFDNLSTIARETGGLGIQVSHSGTVAGILFDGSVPGAVSRAEDCQRILRKRGFEDPWVFHSHSVKDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4U0</accession>
    <name>D3Q4U0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Argininosuccinate lyase</fullName>
            <ecNumber evidence="3">4.3.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2437</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017691.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2437"/>
    <dbReference type="EnsemblBacteria" id="ADD42120">
        <property type="protein sequence ID" value="ADD42120"/>
        <property type="gene ID" value="Snas_2437"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2437"/>
    <dbReference type="eggNOG" id="COG0165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027272_3_3_11"/>
    <dbReference type="OMA" id="YTNGVAA"/>
    <dbReference type="OrthoDB" id="751464at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="6">
        <location>
            <begin position="83"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C2" evidence="7">
        <location>
            <begin position="366"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="395"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="477" mass="50854" checksum="0525FDDEAE9B0EBF" modified="2010-04-20" version="1">MHNTGRVTSTLTATARRIVFGETVDADIDAELGPISEVDMAHCVALAERGLIPADRVRALLAHITALRSCDFAPLRGREAPRGLFMLYESHLSDTIGAEAGGSLHTGRSRNDLKVAVLSLRLRERLRQLTGETLRLQAILLSRALRYGGVVMPVYTHYQPAVPVTYGHYLLGIATALDRDLTALSQAAAGLGTSPLGACGVGGTDLPLDTERVAHLLGFDATAPNSIDAVASRDTALRALFAATSLSLTTSRLATDLQLWSTQEFGLLWFPDDQVGISSIMPQKRNVFLLEHIKAKPAVVSAAAQTLVMAAKGTPFTNSIEVGTEGVSGLWTGLTATLDAVVLSRLLVGAGEPVTGRMAQWARDGWTTATAMANRLVRDGVPFRQAHHRIGDLVRAAGTDGPPPTSPSPTDVVEQTEYGGGPGPKSLDRQYESLRTAWTRHAASHLDWGERLRARRTELAEAVAALIETGTHPGGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Z1</accession>
    <name>D3Q4Z1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4111 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017742.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2488"/>
    <dbReference type="EnsemblBacteria" id="ADD42171">
        <property type="protein sequence ID" value="ADD42171"/>
        <property type="gene ID" value="Snas_2488"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2488"/>
    <dbReference type="eggNOG" id="COG1708">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082941_2_0_11"/>
    <dbReference type="OMA" id="VAWTQRY"/>
    <dbReference type="OrthoDB" id="1607767at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025184">
        <property type="entry name" value="DUF4111"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13427">
        <property type="entry name" value="DUF4111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4111" evidence="1">
        <location>
            <begin position="149"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="265" mass="30257" checksum="954A59221F50E2A6" modified="2010-04-20" version="1">MSDNPAGPTRYPELNELLDELTCRVGDVLGDNLVGMYLCGSFAVGDADMHSDCDFLAVVRRALGRVQERRIRALHSEIPTRAGHWTQHLEGSYPVAAELKTLESLGREWLYIDHGWREMQFHTHCNNEVTRWSLREHGVTLTGPDPKSLVDEVPVEALRSRMLHDIPRFLEDLAAWASWDVAWTQRYAVTTYCRMLNTLETGVVVSKRAALAWAMDSLDPSWRPLLRQVLDDRERGWDPYDPPRPGSIESTMAFSDYVLDRAGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q530</accession>
    <name>D3Q530_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4434</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4434"/>
    <dbReference type="EnsemblBacteria" id="ADD44079">
        <property type="protein sequence ID" value="ADD44079"/>
        <property type="gene ID" value="Snas_4434"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4434"/>
    <dbReference type="eggNOG" id="COG0472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078449_0_0_11"/>
    <dbReference type="OMA" id="RPGRCIK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="288" mass="28286" checksum="E260837136E74AD5" modified="2010-04-20" version="1">MNRLPASLRRFLVTGTGAVVTRAVGSWIARSPAAPKLERINHSGTPVSLSEGPAVAVGASAASALGARTPTHAAAALVAGLGSGAVGLYDDTADIAETPPPKGLAGHLRALAAGHATGGSVKLAGLGLVGLAAATLIDSDRDSGGESRARRVTTTLLGAGVIAGTANLINLFDLRPGRALKLVSSIAGPISTKNDTAGGVAAGTLGAAGAALPDDLEERTMLGDCGANALGALVGLSWTARSGVGKRAALLAGVAALTLASEKVSFTKVIAHTPVLREVDELGRRGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5I5</accession>
    <name>D3Q5I5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NIPSNAP family containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021616.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6429"/>
    <dbReference type="EnsemblBacteria" id="ADD46045">
        <property type="protein sequence ID" value="ADD46045"/>
        <property type="gene ID" value="Snas_6429"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6429"/>
    <dbReference type="eggNOG" id="COG5470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149116_1_0_11"/>
    <dbReference type="OMA" id="CFIRYQI"/>
    <dbReference type="OrthoDB" id="1925073at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012577">
        <property type="entry name" value="NIPSNAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07978">
        <property type="entry name" value="NIPSNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIPSNAP" evidence="1">
        <location>
            <begin position="7"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD46045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="106" mass="12080" checksum="65A985FC42E8EFBA" modified="2010-04-20" version="1">MITCVVEYVIDPAKTDAFERFGHRWIELVNRHGGTHHGYFLPSEGASDKALALFSFPSLAAYEEYRKLFGVDPDFVAADRIRDESGCVLRYERTFMRPLLPEPATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5V7</accession>
    <name>D3Q5V7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015827.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0542"/>
    <dbReference type="EnsemblBacteria" id="ADD40256">
        <property type="protein sequence ID" value="ADD40256"/>
        <property type="gene ID" value="Snas_0542"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0542"/>
    <dbReference type="eggNOG" id="COG3787">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136601_0_0_11"/>
    <dbReference type="OMA" id="IAANDRI"/>
    <dbReference type="OrthoDB" id="1804797at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="7"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="158" mass="17482" checksum="E0482A53A306C6E0" modified="2010-04-20" version="1">MEPVETAKHVIDSNKYLTLGSVLDDGNPWTTPVYFTPDGYHRFYWVSNPDSVHSRNIAARSRVRIVVFDSSVRIGGAEAVFMDAEATLVPEAELADASALYSGRFPELREFGVDELTAPNSLRLYRADALNHEILVRGSDPVFGKGTDSRLLVDIPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q623</accession>
    <name>D3Q623_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2516</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017769.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2516"/>
    <dbReference type="EnsemblBacteria" id="ADD42198">
        <property type="protein sequence ID" value="ADD42198"/>
        <property type="gene ID" value="Snas_2516"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2516"/>
    <dbReference type="HOGENOM" id="CLU_1502579_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="179" mass="19359" checksum="7CDDB56065349DDE" modified="2010-04-20" version="1">MNELSVEGGKLDKLAQHFNNTGTDLLEPYLRLLDGSLPEGVSRYRDYGSLIDGEGLSPIGEEPPPSDPTIIPVSQGDSFFAGLREHDAFFGGLGMRRGTFAKASPVEFGGTDGNGFSHTAAPWAAKLAADWNTAIDYRATDMTRVIQEVYKLADVLIAAVEDYDNVDIYNADGIRQATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q634</accession>
    <name>D3Q634_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TetR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2528"/>
    <dbReference type="EnsemblBacteria" id="ADD42209">
        <property type="protein sequence ID" value="ADD42209"/>
        <property type="gene ID" value="Snas_2528"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2528"/>
    <dbReference type="eggNOG" id="COG3226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_21_0_11"/>
    <dbReference type="OMA" id="SNHARTR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041583">
        <property type="entry name" value="TetR_C_31"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17940">
        <property type="entry name" value="TetR_C_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TetR_C_31" evidence="1">
        <location>
            <begin position="78"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="190" mass="21000" checksum="6091559E7CD06435" modified="2010-04-20" version="1">MKSERARIVADASLEVLAAKGMRGLTHRAVDETAGLAYGSTSNLARTREALLELGLTRLMEIEADRFSRFPSGDLGQGPEAFAEFAAQSIHLLINEHRRITQARYEMALEATRSPRLRKIYDEAGVLPRRYTADLLAATGFQDAERRGRVMVSMIDGIIFDAIAGAGGQPSLDELRRTLREILEGMWHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q676</accession>
    <name>D3Q676_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017822.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2571"/>
    <dbReference type="EnsemblBacteria" id="ADD42251">
        <property type="protein sequence ID" value="ADD42251"/>
        <property type="gene ID" value="Snas_2571"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2571"/>
    <dbReference type="eggNOG" id="ENOG5033MCT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1155828_0_0_11"/>
    <dbReference type="OMA" id="PARMLES"/>
    <dbReference type="OrthoDB" id="1909875at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="240" mass="25617" checksum="56ECB80336A7D5D4" modified="2010-04-20" version="1">MTAPTARPVRVTANLLRSQWWVAAIFWGGLYLLFLTIGVIVSATAGMKESVWIGACWWSQYLMLAAGTVVTSQYVRIFVGHGVTRRTLTIGAVLYGLAGSALFGVLMELGFLAERGIAMAQGLPPFPAATEFVASPARMLESTVEFTLLHVAYFFAGWLISVTFYRHGGVAGIAVIVPALLPGLFMDVVKLGDKPLSELFASVDLTGLPQVVAVSADALSVAVLALLCLLLTRTVPIRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q681</accession>
    <name>D3Q681_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fmu (Sun) domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_2576</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017827.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2576"/>
    <dbReference type="EnsemblBacteria" id="ADD42256">
        <property type="protein sequence ID" value="ADD42256"/>
        <property type="gene ID" value="Snas_2576"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2576"/>
    <dbReference type="eggNOG" id="COG0144">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0781">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005316_0_3_11"/>
    <dbReference type="OMA" id="RVNRQHH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="Fmu/NOL1/Nop2p_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="8">
        <location>
            <begin position="240"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="189"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="355"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="473"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="532" mass="56564" checksum="BAAA104DBE689DAA" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6E0</accession>
    <name>D3Q6E0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017886.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2638"/>
    <dbReference type="EnsemblBacteria" id="ADD42315">
        <property type="protein sequence ID" value="ADD42315"/>
        <property type="gene ID" value="Snas_2638"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2638"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093811_0_0_11"/>
    <dbReference type="OMA" id="RISAQWQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="121"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="265" mass="28450" checksum="CD737AB2AC4633E7" modified="2010-04-20" version="1">MARTLTTDDILRISAQWQWTPFDAVVREDEHVKVVVSNGRATVLRAEAEPGGAEALVSRVRELAAEADPDCTVMWPIHAATEPPDLAEVLARVGAKVEEELDVVALRLPDPDSQLDAPTDVDVRRIDDPALLPDAHQVSSAVFGTPLPTAEFQEREAADVRKQVASGPARVIFRYVAYADGEPVGAAGTTLEDGVAKLWGGSVVESHRGRGVYRALLKTRMDEAAALGADLALVKARTGTSGPILRRAGFTVHGREYVYGMPARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6G5</accession>
    <name>D3Q6G5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase HflX</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein HflX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflX</name>
        <name evidence="8" type="ordered locus">Snas_4564</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">May associate with membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019779.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4564"/>
    <dbReference type="EnsemblBacteria" id="ADD44208">
        <property type="protein sequence ID" value="ADD44208"/>
        <property type="gene ID" value="Snas_4564"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4564"/>
    <dbReference type="eggNOG" id="COG2262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019597_7_0_11"/>
    <dbReference type="OMA" id="AEMKTGR"/>
    <dbReference type="OrthoDB" id="1592033at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="PTHR10229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="7">
        <location>
            <begin position="245"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="185"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="466" mass="50454" checksum="1EB39AF40824A7D6" modified="2010-04-20" version="1">MPTNDTELPDTGQLALEERHALRRVAGLSTELTDVTEVEYRQLRLERVVLVGVWTKGTLTEAENSLAELAALAETAGSQVLDGLIQRRKSPDPATFVGRGKVDELTEAVTASGADTVICDGELSPSQLRNLEAEIKVKVIDRTALILDIFAQHATSREGKAQVELAQLEYLVPRLRGWGETLSRQAGGRAGGAGGGVGLRGPGETKLETDRRRIRTRIAKLRRDIAKLRTVRDTKRSSRRRHSVPSVAIAGYTNAGKSSLLNRLTGAGVLVEDALFATLDPTTRRARTGDGRDYTLSDTVGFVSHLPHQLVDAFRSTLEEVADADLIVHVIDGSHPDPGAQVRAVREVLNDVGADAVPEVLVVNKIDRAGSEALLTLRTDWPDAVFVSAHTGEGVDKLRDVIEERLPRPAVPLLVCVPYVRGDLAARVRQRGQVRSIDHRGDGTVMDVLVDEALAAELAPFVIDTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6H6</accession>
    <name>D3Q6H6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019790.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4575"/>
    <dbReference type="EnsemblBacteria" id="ADD44219">
        <property type="protein sequence ID" value="ADD44219"/>
        <property type="gene ID" value="Snas_4575"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4575"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="VILAYDC"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="150"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="224" mass="24207" checksum="79B4D892EC91C138" modified="2010-04-20" version="1">MIKVLLADDQSLLRLGFRAVLDKQPDLEVVGEAADGERAVAMTRALRPDVVLMDVRMPVMDGIEATRRILASGSAARVLVLTTFDLDEYVFAALRAGASGFLVKDATPAELTGGIRVVAAGDAAVAPGVTRRLIERFAEHLPATERVPPGDDRLNSLTEREHDVLVQVARGRSNQEIAELIHVSQATVKVHVGRILAKLGLRDRAQVIVFAYENGVVRPGEPHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6K0</accession>
    <name>D3Q6K0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ectoine/hydroxyectoine ABC transporter, permease protein EhuC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_4599</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019814.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4599"/>
    <dbReference type="EnsemblBacteria" id="ADD44243">
        <property type="protein sequence ID" value="ADD44243"/>
        <property type="gene ID" value="Snas_4599"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4599"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_4_11"/>
    <dbReference type="OMA" id="QLVPMWA"/>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014342">
        <property type="entry name" value="Ectoine_EhuC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03004">
        <property type="entry name" value="ectoine_ehuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="18"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="246" mass="26664" checksum="8FBDBED424429325" modified="2010-04-20" version="1">METLKILQNSWDQLLEGLWITVLVTVLGCLGTLVISFILGLMAGSKNIATRGVARTIIEFFRGTSLVVQLFWFVFAMPIMFKVKFDSVIAVGIVVLALNYGAYGSEIVRGAINAVPKAQWEACVALNFTFWQKLSLVIIPQAWVGMVPPFSNLAIQVLKGSALVSLIGLVDLTLAAQQLRTKASAEGAIVIFAALLVIYFIMSFLIAAGMRYLERRAKASIGQAPPEKQSIFARTPVKAKEAGGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6R0</accession>
    <name>D3Q6R0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019874.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4660"/>
    <dbReference type="EnsemblBacteria" id="ADD44303">
        <property type="protein sequence ID" value="ADD44303"/>
        <property type="gene ID" value="Snas_4660"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4660"/>
    <dbReference type="HOGENOM" id="CLU_1833982_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="140" mass="14575" checksum="F7EB293F19258793" modified="2010-04-20" version="1">MSETAIAEPATRAKATGLARTTRINAILIAVVTLAQPVWIGLLFTGSVFGAVAHGIGAGALVLLSLIHLVLSIVRSRGRGKSEVWGNLAFIGLIVAQSLLGVFQLYPLHFPVGVLMAIGSVHLVQATNKEVRDAGTEAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q725</accession>
    <name>D3Q725_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015995.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0711"/>
    <dbReference type="EnsemblBacteria" id="ADD40424">
        <property type="protein sequence ID" value="ADD40424"/>
        <property type="gene ID" value="Snas_0711"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0711"/>
    <dbReference type="eggNOG" id="ENOG50331GF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128226_0_0_11"/>
    <dbReference type="OMA" id="ALWHVWH"/>
    <dbReference type="OrthoDB" id="1804797at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="173" mass="18601" checksum="E2BA0B5985C32903" modified="2010-04-20" version="1">MTDEVTPNPAPHPLTTEAAKKAQIAWIGVGSAPAACLWCLWIDDALHLVCGPGEQPDPGLDTADECHVTLRGDHNGRIVDFTATVARLDPADDSWSETATALAAKRLNATDGDTVERWRTECALYRLAPKPDEAPLSGAALPSASLAATVVPSPAARPTRKPFRLHRVKRRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q749</accession>
    <name>D3Q749_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2643</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017891.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2643"/>
    <dbReference type="EnsemblBacteria" id="ADD42320">
        <property type="protein sequence ID" value="ADD42320"/>
        <property type="gene ID" value="Snas_2643"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2643"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="PRREEVM"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="12"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="245" mass="26351" checksum="BC44C6FA8DB30A67" modified="2010-04-20" version="1">MDTIGRTDTEVVRVEAVTKDYGTVKALRGVDLDLPGGGFTAVMGPSGSGKSTLLHCAAGLDRPSSGSVWLGATDLATLSETALTELRRTRIGFIFQAYNLIGSLTVEQNITLPLRLAGARADPDWLAEIVTQVGLDQRLTHRPARLSGGQQQQVAIARALITRPAVVFADEPTGALDTRTGQQVLELLRRMVDTFGQRVLMVTHDPVAASWADRVVFLADGKLAGELRRPDPEQVAARLTTLGEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q762</accession>
    <name>D3Q762_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2656</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017904.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2656"/>
    <dbReference type="EnsemblBacteria" id="ADD42333">
        <property type="protein sequence ID" value="ADD42333"/>
        <property type="gene ID" value="Snas_2656"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2656"/>
    <dbReference type="eggNOG" id="ENOG5033AMN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_178406_3_1_11"/>
    <dbReference type="OMA" id="QAEFSGW"/>
    <dbReference type="OrthoDB" id="2084431at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043758">
        <property type="entry name" value="DUF5703"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18963">
        <property type="entry name" value="DUF5703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="72" mass="8009" checksum="9B7C40AF43C649A9" modified="2010-04-20" version="1">MDDESSSPGSYEYAPLRLPTDIDNLSAQAQLSVAAEYGGWELARVRRYADGTRKVTLRRKTSSRTLLPGLCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7D2</accession>
    <name>D3Q7D2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2727</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017974.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2727"/>
    <dbReference type="EnsemblBacteria" id="ADD42403">
        <property type="protein sequence ID" value="ADD42403"/>
        <property type="gene ID" value="Snas_2727"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2727"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="FTCICIN"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="447"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="21"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="480" mass="48237" checksum="314AFEC1D65FB5C5" modified="2010-04-20" version="1">MTVDIEPSRAIPAHSWRRWVGLTGLLLAEAMNLLDATITTVAAPVIRADVHGSASSLQWIAATYTLPFAIALIPGGRLGDIHGRRRILLISLAGFLASSTVCAVAPSMAVLLPARAVQGVCAGLLIPQTIGLIKAMFDGAALGRALSLIGPVMGLTAVAGPVLGGVLTSADIAGLSWRVVFLANLPLGLAVLGSIRFLPEDRADRKPSIDVSGALIATAVAAALLVPAIDATIPPWARLALVAVGLIGAAGLAVHMRKTRARGRDPIVEPSLFRDRGFPAALLSSVLYFAVSTGLVFVVVLYVQEGLGASVLVASLTVLPFSLGLAVASLLAGQVLLARTGPKLMLVGVGLLGLGCAGGVVAANLAPAANLAPVPSLSPWLPVSLGLAGIGGGLVTVPFFTAALARVRPHETGSAAGLLNSVQQLGGTAGVAGLGAVYLHHTGTPGGALAIVFGTCLAIALVLAVSATAMLSSPKDVGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7F8</accession>
    <name>D3Q7F8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, RpiR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018000.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2753"/>
    <dbReference type="EnsemblBacteria" id="ADD42429">
        <property type="protein sequence ID" value="ADD42429"/>
        <property type="gene ID" value="Snas_2753"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2753"/>
    <dbReference type="eggNOG" id="COG1737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055769_0_1_11"/>
    <dbReference type="OMA" id="RYAMLAM"/>
    <dbReference type="OrthoDB" id="992687at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05013">
        <property type="entry name" value="SIS_RpiR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000281">
        <property type="entry name" value="HTH_RpiR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035472">
        <property type="entry name" value="RpiR-like_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01418">
        <property type="entry name" value="HTH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51071">
        <property type="entry name" value="HTH_RPIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH rpiR-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="134"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="304" mass="32940" checksum="FB56C58962FA7272" modified="2010-04-20" version="1">MSGNLAATGLLGRLRTELPTLPDALRRVAELVLRDPVDTTHMSIVDLAERSRTSTATVTRFCRTMGYPGYAALRVAIASETGTAAQQTRWDTDIDSQIEPDHPVGRVLEIIAAADTRAIADTAFQVDTAAIDRIATAIAAASRVELCGMGSSGTAAREMAFRLERIRVPCWFRPDAHTALTNAALLTESDVAIGISHSGRTREIVEVLAEAGSHGALTVAVTSFRRSPLADTADVVLSTQVFETTFRLAALSALHSQLLLLDLIYVAVAQRTYTRTTEAFEVTARAVEAHRMATESRRRRNRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7J5</accession>
    <name>D3Q7J5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4694</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4694"/>
    <dbReference type="EnsemblBacteria" id="ADD44337">
        <property type="protein sequence ID" value="ADD44337"/>
        <property type="gene ID" value="Snas_4694"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4694"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="OMA" id="SRWHRTI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="80"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="306" mass="32979" checksum="CA01A487D41E44F4" modified="2010-04-20" version="1">MPSRAPSRRRSPATWVRGGGLTNLLFLAPLLLVFGAFAWVPIGQAVVMSFQQTNLVTPAQFVGLDNFETVLADPLLWTAIGNTAWFALLALLFGYPIPLVAAVLMSEVRKWRGLYSAIAYLPVVIPPVVAVLLWKFFFDAGPNGVFNTILGFVGLDAVPWLQDATTAMPSLVLEATWAAAGGTMIIYLAALTGVPPELYEAAEIDGASVWGKVWHVTLPQLRGVLLITFILQIIGTAQVFLEPFLFTGGGPANSTTTLLLLIYRYAFADSLGGDYGAATALSLMLAAFLALFSAVYFRLTRSWSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q822</accession>
    <name>D3Q822_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016098.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0815"/>
    <dbReference type="EnsemblBacteria" id="ADD40527">
        <property type="protein sequence ID" value="ADD40527"/>
        <property type="gene ID" value="Snas_0815"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0815"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_46_0_11"/>
    <dbReference type="OMA" id="HRMVPAD"/>
    <dbReference type="OrthoDB" id="1309950at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041669">
        <property type="entry name" value="TetR_C_15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17918">
        <property type="entry name" value="TetR_C_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="20"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="207" mass="22309" checksum="2A9B2F9A85304C39" modified="2010-04-20" version="1">MGAKSGRFQPRKNPSQHRARLTRDRILAAAAQVFASHGYAAGTTDRIAAAARISIGSLYQYFPNKDAVLLALSQAHLEAATDAIRAVLAEAGEDWLDGVIAAVIDGHAANPRLHKVLFDEAPRTPELLDRLRAAESAIAATIAERLRGDGRFDVEDPDEAADLVVATVESLTHHFVARDPDGFDAATTQQRISELLTRHLRPAPPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q856</accession>
    <name>D3Q856_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hyaluronate lyase</fullName>
            <ecNumber evidence="6">4.2.2.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0850</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide lyase 8 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.1" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0850"/>
    <dbReference type="CAZy" id="PL8">
        <property type="family name" value="Polysaccharide Lyase Family 8"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40561">
        <property type="protein sequence ID" value="ADD40561"/>
        <property type="gene ID" value="Snas_0850"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0850"/>
    <dbReference type="eggNOG" id="COG5492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004172_4_1_11"/>
    <dbReference type="OMA" id="RYYQDET"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030340">
        <property type="term" value="F:hyaluronate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038970">
        <property type="entry name" value="Lyase_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011071">
        <property type="entry name" value="Lyase_8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012970">
        <property type="entry name" value="Lyase_8_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004103">
        <property type="entry name" value="Lyase_8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003159">
        <property type="entry name" value="Lyase_8_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38481">
        <property type="entry name" value="PTHR38481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02278">
        <property type="entry name" value="Lyase_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02884">
        <property type="entry name" value="Lyase_8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08124">
        <property type="entry name" value="Lyase_8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="SSF48230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49863">
        <property type="entry name" value="SSF49863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049783" evidence="2">
        <location>
            <begin position="30"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="domain" description="Lyase_8_N" evidence="5">
        <location>
            <begin position="41"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Lyase_8" evidence="3">
        <location>
            <begin position="398"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="Lyase_8_C" evidence="4">
        <location>
            <begin position="680"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="792" mass="83565" checksum="3D901AEA8EEF9DA7" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q874</accession>
    <name>D3Q874_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018019.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2772"/>
    <dbReference type="EnsemblBacteria" id="ADD42448">
        <property type="protein sequence ID" value="ADD42448"/>
        <property type="gene ID" value="Snas_2772"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2772"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_591393_0_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098542">
        <property type="term" value="P:defense response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="141"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="466" mass="51871" checksum="660D1AF2E5B382A6" modified="2010-04-20" version="1">MRQAPAVPDCRTPDEVCAYLQQLRTWAGGVSFRELTLRDNAIRLSRNARQTARQTVNDCFQQGRKRLDRDLVLDIAKALGLPEASLLRLDQVCQVADGRRSIAALADVSDSIPAGSGEFTGREPLLERALTAVEDAWARRSQPVVAFTGPAGMGKTELAVQLAHRLPRKYPDLSRRFFVDLHGFDTRLEPTPPFEVLAAIVKLLGVRDSAILALSTVEQMWDRLLNTLAGQRALLLLDNVSDAAHLGQFTSGAPNLAIVATSQERLPLTEPGHGIEVGPLDYPSCVRLLDGFDRLGRVNREPGVTVRLINELCGGRPFDLVALGGQLSDPAEAAWSLADHADRLAALPRDEASHPILAGSCHRLEPEIRRVFRLLGLYPGFDFSAYDIAVLADRDVDLIDKYLERLYDRHLLVRRHAHRYRLHDVVAAYSRRLLHREESPTNQRQALRRLHTATTLNANNRLGPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q891</accession>
    <name>D3Q891_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2789</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018036.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42465">
        <property type="protein sequence ID" value="ADD42465"/>
        <property type="gene ID" value="Snas_2789"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2789"/>
    <dbReference type="eggNOG" id="COG3214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043035_2_0_11"/>
    <dbReference type="OMA" id="LEMYKPA"/>
    <dbReference type="OrthoDB" id="1594634at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009351">
        <property type="entry name" value="YcaQ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06224">
        <property type="entry name" value="HTH_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="362" mass="41151" checksum="21626982C184281D" modified="2010-04-20" version="1">MTPHRLDRVEARRIAVRAQLLDAPRPTDLLDVARQLTLLQVDPTAAIAPSADLVAWSRLGSSYRPADLTRALEVERTMFEHNAMLRPMEDLRLHLADMAEYPADWEFGRKWLDDNESFRRDILELLKTSGPLLSRDIPDTSKVSWPSSGWTNNRNVTKMLEMLLKSGEVAITARQGRQRVWDLPERVYPADAKALSLEESHRLMNERRVRSLGIVRPNAFGSPGEQLSVADSGEPAVVEGIEGEWRVDPAAIGKPFSGRTALLSPFDRLVHDRDRAMELFDFEYILEMYKPKDKRRWGYFALPILHGDRLVGKLDAKADRKAGKLDVFAIHEDVPFTKAISKGVRDEIQDLAQWLGLDPVWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q897</accession>
    <name>D3Q897_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018042.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2795"/>
    <dbReference type="EnsemblBacteria" id="ADD42471">
        <property type="protein sequence ID" value="ADD42471"/>
        <property type="gene ID" value="Snas_2795"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2795"/>
    <dbReference type="HOGENOM" id="CLU_2411759_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="92" mass="10059" checksum="1D907EB8AF2BBFFD" modified="2010-04-20" version="1">MFDEIHSRHGRDGREARTALPVSPRLKAVTAASGALACLTLAAVLWATGWGPGWLAVVVLVIGVWAVADTGLQWHRYRVRNRDNPTRKGTQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8B4</accession>
    <name>D3Q8B4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018059.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2812"/>
    <dbReference type="EnsemblBacteria" id="ADD42488">
        <property type="protein sequence ID" value="ADD42488"/>
        <property type="gene ID" value="Snas_2812"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2812"/>
    <dbReference type="eggNOG" id="ENOG50331ZU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156547_0_0_11"/>
    <dbReference type="OMA" id="VISVAHE"/>
    <dbReference type="OrthoDB" id="2057744at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="110" mass="11870" checksum="564A0F5E287CB165" modified="2010-04-20" version="1">MSTDNHWATDACTLPSEQQPLREAEFAELFAASLRSVERVAPTRLRLLLDASARAETVRLTEAESSCCSFFTFTIGEAAPGRIGVDIAVPRAQVPVLDGLARQASALVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8E4</accession>
    <name>D3Q8E4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018089.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2843"/>
    <dbReference type="EnsemblBacteria" id="ADD42518">
        <property type="protein sequence ID" value="ADD42518"/>
        <property type="gene ID" value="Snas_2843"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2843"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050691_0_0_11"/>
    <dbReference type="OMA" id="GHEPISI"/>
    <dbReference type="OrthoDB" id="1869225at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="23"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="401" mass="42772" checksum="3AF04C4E783239B7" modified="2010-04-20" version="1">MPGPDPSTATQLDLIAGHFGKRLKYWRLTRQLTQAELARDLNLDGSYVSKLESSRRRPSLDIARQCDDLLDTGGELADLLTLVATDPGPPVATVGAPLPTISPTTARTTALPAAAPAHATVSLNRLAEAYAEVAATMGGHHLGESVERQAQEIIGRHIGSPESLSGGLLRTAARFARLAAAIRLDSLDEAGALYWNDCAGRWALDGGDPALSAEMCARTAIVYAHRDNAPTALTLATRAEQLAPHAPTATVWSLLAQAHAHAASAEPDQTTGALATAHKLLTELDSPLMANPSTYSDNHLWHWHAGLCHLTLARHDIDRTTNANRALDQLRQALSEVSVYHTRELALTRLALAHAYLHADDPVSATAELTEAATLARACTSPRLHTELAQTTTILATTTHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8E7</accession>
    <name>D3Q8E7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular ligand-binding receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2846</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018092.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2846"/>
    <dbReference type="EnsemblBacteria" id="ADD42521">
        <property type="protein sequence ID" value="ADD42521"/>
        <property type="gene ID" value="Snas_2846"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2846"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_1_2_11"/>
    <dbReference type="OMA" id="QTTFHYA"/>
    <dbReference type="OrthoDB" id="538961at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049789" evidence="1">
        <location>
            <begin position="29"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="34"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="400" mass="43150" checksum="A6EDA40950DD2E23" modified="2010-04-20" version="1">MTQRLRRRAFVTAAVAALALTATGCSSGSEDAGTVKIGWEIPKSGTYETLGKDLDAAFNLYLDTHGGKLGGRKVELKTVDETDKPEKALDAANKLIKQDEVVAMAGIQSSGSYEAIAPVAQENGIPLVGAGGRPQLEKNKDLDGLKGLWHTSWINAQTGQSIAPYIKKKIDGPVYAIGPDYEGGYANVEGFTDEFKKIGGKLANEKDGKPTYTPFPKIDDFGPYLTKIANSDAKAVYCFYAGANAIDFVKQYAESDAADIPLYGAFYTEGKVLEAQGKSAKGMYSTMNYSPDLDNEANREYVAEWTKKEQGQPSVYATAAWDAAQVLDLAIGSIPKGEEVTSEAITEAIGKLGKIKSPRGEWHLGEKTHAPIQKWYLREVKEDGGVLSNVRIEDLETLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8K6</accession>
    <name>D3Q8K6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative transcriptional regulator, PucR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4807</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CdaR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020019.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4807"/>
    <dbReference type="EnsemblBacteria" id="ADD44448">
        <property type="protein sequence ID" value="ADD44448"/>
        <property type="gene ID" value="Snas_4807"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4807"/>
    <dbReference type="eggNOG" id="COG2508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037725_0_0_11"/>
    <dbReference type="OMA" id="AFTEWFR"/>
    <dbReference type="OrthoDB" id="1439158at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041522">
        <property type="entry name" value="CdaR_GGDEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17853">
        <property type="entry name" value="GGDEF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF_2" evidence="3">
        <location>
            <begin position="159"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_30" evidence="2">
        <location>
            <begin position="317"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="386" mass="40736" checksum="ADDE0988A34C6C6B" modified="2010-04-20" version="1">MELAATIQKIERAASALATQSVARMDAELPWFRELPAEQRAMVTLVAQAGVGSFVEWLRGDGEAPAVGDEVFDGAPRELARLIRLQHTVALIKVTIDVVEEQVPHLAAPGEEEALHIAVLKFSREVAFGAARVYARTAETRGAWDARLQAMLVDGLLRGDDGDEIAGRAAALGWGDSSPVAVVVGRSPGGEAAVILHAVHRATRRMGIDVVAGVHGERLILVLGGSTEPEEVAGKLVGQFGEGPIVVGPATPSLAEAGASARAALSGHRAAPAWPGAPRPVSAHQLLAERALAGDNEARRILRIDVYNALERAGGSLLSTVDTFIATGGVLEGTARAVFVHPNTIRYRMRRVAEVTGFSPFVPHDAFTLHVALTIGRLDPTSDVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8T1</accession>
    <name>D3Q8T1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TAP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4882"/>
    <dbReference type="EnsemblBacteria" id="ADD44523">
        <property type="protein sequence ID" value="ADD44523"/>
        <property type="gene ID" value="Snas_4882"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4882"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_3_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048318" evidence="1">
        <location>
            <begin position="30"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="104"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="493" mass="53109" checksum="5F1E6BC7AA7E6940" modified="2010-04-20" version="1">MRRRWYPAMAAVAVVAAGLTWTGLPSAQAQSSDLDWSDCGGRAQCATLTVPVDWNDPDGPTTRVNLAKLPARDPGAADRPLLVNLGAGNTTAALEADQVPPGVAALNERFDVIGFDPRGLGKDANDTLIHCAESQAPYPGLVLAEDAKDWRAHAKRNAKYERSCREAAGAEYAGLTSTQIAHDMDALRTALDQPKLKYFGNSYGTSYGQAYAELFGDKVERMYLDGVADHTQPKLSDWLTNYARTTEQQLTEFADWCSTRDGCALNDEDAAKVWDDLVKRAETEPIPAPGAGDGETVNVRELLAGGHFGLTPTSWPRLAVAMDSARDGDASDFLTELVWPPDTGKGGHVQGALLCNDFMPEQLSYRQTLKLEKRLRDIAPRIGWVTARAELSRCVGMDAKPANPPHRLDVDDLPPVLVGIGDLDANTPHHGAENVASQLPDASVLRHGDGHAAFVLGNKCLANHVTAYFADGTLPDEGTRCPGELVDQIPDKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9S6</accession>
    <name>D3Q9S6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HEPN_SAV_6107 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020193.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4985"/>
    <dbReference type="EnsemblBacteria" id="ADD44622">
        <property type="protein sequence ID" value="ADD44622"/>
        <property type="gene ID" value="Snas_4985"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4985"/>
    <dbReference type="eggNOG" id="ENOG5032S47">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096112_0_1_11"/>
    <dbReference type="OMA" id="IRSAWEV"/>
    <dbReference type="OrthoDB" id="2046838at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040891">
        <property type="entry name" value="HEPN_SAV_6107"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18726">
        <property type="entry name" value="HEPN_SAV_6107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN_SAV_6107" evidence="2">
        <location>
            <begin position="65"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="169" mass="18370" checksum="7E44FCA4D0AA3977" modified="2010-04-20" version="1">MLATLTSDTDVASTRPLPQRPSQRLPEIPAQTTTDRDRKAIPARSMPNRSPLELLILARQGLAEAAEEPHDGPRYATAHLAALRAAAAVLAIRARPVAGHRSQVTNVWSLLIQVAPELREWAEFFAATARKRTMAQAGVASVVTAREADDLLRDADHFVSVVTDLIGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA82</accession>
    <name>D3QA82_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1084</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016365.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1084"/>
    <dbReference type="EnsemblBacteria" id="ADD40794">
        <property type="protein sequence ID" value="ADD40794"/>
        <property type="gene ID" value="Snas_1084"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1084"/>
    <dbReference type="eggNOG" id="COG1814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038957_3_0_11"/>
    <dbReference type="OMA" id="SRIGWLR"/>
    <dbReference type="OrthoDB" id="1717935at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:cellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="PTHR31851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="241" mass="24688" checksum="B95662CBC53D10D0" modified="2010-04-20" version="1">MTDTPADQPHPGEPHHERLGDKLNWLRAGVLGANDGIVSTAGIVVGVAGASTSRLAIFTAGLAALVAGALSMAGGEYVSVSSQRDTERAMIRKEKRELKTMPEAEERELAGLYEQRGLSPELAAEVARELTKKDALAAHAEVELGIDPDAPANPWTAAFASFVSFSIGALLPLVAILLPSVSLRVGACAAAVVLALVLTGLISARLGQAGPGPAIARNVGIGVVTMAVTYVVGHLFGVATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-04-07" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAF0</accession>
    <name>D3QAF0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyl-gamma-glutamyl-phosphate reductase</fullName>
            <shortName evidence="1">AGPR</shortName>
            <ecNumber evidence="1">1.2.1.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">N-acetyl-glutamate semialdehyde dehydrogenase</fullName>
            <shortName evidence="1">NAGSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">argC</name>
        <name evidence="3" type="ordered locus">Snas_3062</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.38" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3062"/>
    <dbReference type="EnsemblBacteria" id="ADD42733">
        <property type="protein sequence ID" value="ADD42733"/>
        <property type="gene ID" value="Snas_3062"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3062"/>
    <dbReference type="eggNOG" id="COG0002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006384_0_0_11"/>
    <dbReference type="OMA" id="PHLTPMI"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="2">
        <location>
            <begin position="18"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="352" mass="35897" checksum="799EF6BF266C9610" modified="2010-04-20" version="1">MLCIEIHKPEEVDSMGNRIAVAGASGYAGGEVLRLLAGHPNIEIAAVTAHSKAGQPVTDTHPHLRSLAGRTFAETTVDALAEADLVVITLPHGQSAELAAKLPADAKIVDLGADHRLVDAAAWEAYYDGPHAGAWTYGLPELPGGREAIAASKRVAATGCYAVATTLALAPILASGIGQPDDVVVVAASGTSGAGSAAKPHLMASEVAGSLSPYKVGAHQHVPEIKQATRARSLSFTPVLAPMPRGILSTVTVKPADAGLTTAEVHEVLAAAYADEPFVHVLPNGSWPRTADTLGSNSCHLQATMDSDADRIIVTAAIDNLGKGAAGQVVQCANLMLGLDETAGLNVDGVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAX3</accession>
    <name>D3QAX3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020340.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5134"/>
    <dbReference type="EnsemblBacteria" id="ADD44769">
        <property type="protein sequence ID" value="ADD44769"/>
        <property type="gene ID" value="Snas_5134"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5134"/>
    <dbReference type="eggNOG" id="COG1787">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1276974_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Mrr_cat" evidence="2">
        <location>
            <begin position="77"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="216" mass="23493" checksum="B9F6108D54AEA847" modified="2010-04-20" version="1">MRNLSAPAKAVIALVGLILGFAVVKYVFAWIAANWFTLVVGLTLLVGLTVGAVLFRRHQTQADRLENRELERHLESIDDMDLPQFESWIGQQLLSHGFRKVRYVGRSGDFGSNFVATAPAPDTRRVMVRAKPDDGTLSRRGARHIQALGADAHARWKADTAILVTNADLHPLKTAARHDALAQQLGVVLVDRLELAAWVADRKPPAALTAAPAAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB86</accession>
    <name>D3QB86_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmC</name>
        <name evidence="6" type="ordered locus">Snas_1193</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016474.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1193"/>
    <dbReference type="EnsemblBacteria" id="ADD40903">
        <property type="protein sequence ID" value="ADD40903"/>
        <property type="gene ID" value="Snas_1193"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1193"/>
    <dbReference type="eggNOG" id="COG0255">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158491_3_3_11"/>
    <dbReference type="OMA" id="RFQMATS"/>
    <dbReference type="OrthoDB" id="2063644at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_L29_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="79" mass="8983" checksum="B9CD24E018D15739" modified="2010-04-20" version="1">MAAGIEAAELRELSDDELRTRLRDSKEELFNLRVQSATGQLDNNRHLKTVRRDIARIYTIMRERELGLSAAPTTEVASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBC2</accession>
    <name>D3QBC2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1229"/>
    <dbReference type="EnsemblBacteria" id="ADD40939">
        <property type="protein sequence ID" value="ADD40939"/>
        <property type="gene ID" value="Snas_1229"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1229"/>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_359783_0_0_11"/>
    <dbReference type="OMA" id="EWFAGAD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="748" mass="82293" checksum="6BD2990F143BA48F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBJ0</accession>
    <name>D3QBJ0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018443.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3202"/>
    <dbReference type="EnsemblBacteria" id="ADD42872">
        <property type="protein sequence ID" value="ADD42872"/>
        <property type="gene ID" value="Snas_3202"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3202"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_59_2_11"/>
    <dbReference type="OMA" id="HWASAEH"/>
    <dbReference type="OrthoDB" id="1459004at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="227"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="330" mass="35405" checksum="DB696ACCA7E51031" modified="2010-04-20" version="1">MCKDSAMVLSRHLVAVLALEGVIPFELGIPARLFGMARGPDGQRLYDVVTCTLTPGRLATNADFDIVVDEGPEVLARADTVVIPASYHVDLAIGDNGLPEPLAEALASLKPGTRLASICTASFILAAAGLLDGRRATTHWMHAEALARAFPKVDVDADVLFVDEGDVLTSAGVAAGVDLCLHMVRRDHGSKVANAVARRSVVPPWRDGGQSQYIEQPVPSTAAASTAEVRAWAIAHLDERVSIAGLARRARMSVRTFTRRFHDETGAAPGQWLLRQRVEAARVLLETTDLSADRIAARTGLGTSASLRRHFHAQVGVAPMTYRKTFHANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBK8</accession>
    <name>D3QBK8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Response regulator receiver</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018461.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3220"/>
    <dbReference type="EnsemblBacteria" id="ADD42890">
        <property type="protein sequence ID" value="ADD42890"/>
        <property type="gene ID" value="Snas_3220"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3220"/>
    <dbReference type="eggNOG" id="ENOG503303C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_674275_0_0_11"/>
    <dbReference type="OMA" id="RYCRDND"/>
    <dbReference type="OrthoDB" id="1906961at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="376" mass="39357" checksum="BB71737E48D3622E" modified="2010-04-20" version="1">MKTATTCKRCGTPIPQQQGRGRPRLYCEGSDCQAAAKRTRALRRTTPGLEGALARAEDLYERMEAELAAAIQPLAESLAAELDPAKVEEKIAQASQAADARVAAARAERDDALAKAAQASKAEAGARAEAQAAVAEAEAARSDATEHAEAAAIAEHRAVRAEQSAREAEQAAAEAGEVAAAAERARTVALAERDEAIEERDEAEARAEAAQAAQRVAQEKSAALVVERDIARAGQREAETQRMDAVSAAAVAVAETQRLRGELETVRAEAAAQLDSVRSEAAARIDAAEHQAANARDDAAASAAERDQLNGQLAALRLRLDDFRSTIQQARSESAALRERAVAAELELRALRAAAAPPEEMGSPTGNGEDGPAARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBM8</accession>
    <name>D3QBM8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018481.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3240"/>
    <dbReference type="EnsemblBacteria" id="ADD42910">
        <property type="protein sequence ID" value="ADD42910"/>
        <property type="gene ID" value="Snas_3240"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3240"/>
    <dbReference type="eggNOG" id="COG5563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_782815_0_0_11"/>
    <dbReference type="OMA" id="WIAGTME"/>
    <dbReference type="OrthoDB" id="415763at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049718" evidence="2">
        <location>
            <begin position="30"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="354" mass="36480" checksum="824A3BD22F1BF2F3" modified="2010-04-20" version="1">MNARPKLLLALAGGVAAAAIAVPVVSAVADGSPPAGNSASNSTADCELTELAFPDGYDKDVKARSVSASGEYAAGGALGEDGDNPVLWHDGKAIVPEELKSDTTGASAVNDSGQMVGSRGAGEATVPWLYQDGKVTNLKVPKGQSGNSRDINNAGQVVGYTQDDEGRTFPALWPSPDAEPVLLDNPFEDGGGRAYSINEEGTISGKLIDPQDMTVHLWKWTADGKGEELKRPDPGDMVDQDVKTSISGDHVVSVNIAPIGAFPAYAWNLSEGTDGTEIGLPVVEAVSADGTIVGLSKDDKPAMLIDGAVTELPGVQGPASNTDVAHDINQKGDVIVGGVVDENDKQHPAMWNCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBM9</accession>
    <name>D3QBM9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018482.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42911">
        <property type="protein sequence ID" value="ADD42911"/>
        <property type="gene ID" value="Snas_3241"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3241"/>
    <dbReference type="eggNOG" id="ENOG503395P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1069229_0_0_11"/>
    <dbReference type="OMA" id="CNTSECA"/>
    <dbReference type="OrthoDB" id="1205201at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048417" evidence="1">
        <location>
            <begin position="24"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="26450" checksum="DC0051E0ACDC713B" modified="2010-04-20" version="1">MRRFLIPLSLAFAVIAMPTPAFAAVPGNDEPAGAVDLGSLPAAVTQDTTEATYTPHGGCTSGDAGANVWYTLTVDADQRVVVDTAGSDYNTGLNVFAGDPDTGGFVGCSERNLRFDGFSGVTYYIEIAACCGSSTGGQLALSVSQAPEPPAVSVTVDPNGQFDTAGRATITGTASCAATVQFASVEVFVSQRVGRVIITGQNGANLDCEPGGAEVPWSVTVTGGNGLYRGGQATASVQSVGCNTSECASNFTEAAVRLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBU7</accession>
    <name>D3QBU7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5201</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5201"/>
    <dbReference type="EnsemblBacteria" id="ADD44836">
        <property type="protein sequence ID" value="ADD44836"/>
        <property type="gene ID" value="Snas_5201"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5201"/>
    <dbReference type="eggNOG" id="COG4941">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035311_1_1_11"/>
    <dbReference type="OMA" id="QVGPYQL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="3"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="93"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="50"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="393" mass="42832" checksum="9752F30F797C217E" modified="2010-04-20" version="1">MVRRYGHFDESEDAVQEALLTAATRWPTDGLPDNPRAWLITVASRRLTDQLRSDEARRRREDTVAARQLPEDTQAPAADAPDTNADDTLILLFMCCHPSLTAASQIALTLRAVGGLTTAEIAHAFLVPEATMAQRISRAKQQVKASGLPFQMPPAPERAAKLGAVLHVLYLIFNEGYTATSGPNLRRAELSNEAIRLTRAVHRLLPDDGEVTGLLALMLLTDARRDARNTATGDLVPLADQDRSRWDRRSIAEGVDLISHALATAPPGPYQVQAAIAAIHDEAPSTEATDWPQIVALYAVLDNLAPGPMVTLNQAVAVAMVDGPRAGLELLSRLDDDPRMARHHRLEAVRAHLYEMDGDPAAARAAYLAAATLTTSLPEQDYLRWRADKLPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBV8</accession>
    <name>D3QBV8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrate reductase, beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5212</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020418.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5212"/>
    <dbReference type="EnsemblBacteria" id="ADD44847">
        <property type="protein sequence ID" value="ADD44847"/>
        <property type="gene ID" value="Snas_5212"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5212"/>
    <dbReference type="eggNOG" id="COG1140">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043374_5_2_11"/>
    <dbReference type="OMA" id="VYFNWQT"/>
    <dbReference type="OrthoDB" id="1762646at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009325">
        <property type="term" value="C:nitrate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008940">
        <property type="term" value="F:nitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042126">
        <property type="term" value="P:nitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029263">
        <property type="entry name" value="Nitr_red_bet_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038262">
        <property type="entry name" value="Nitr_red_bet_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006547">
        <property type="entry name" value="NO3_Rdtase_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14711">
        <property type="entry name" value="Nitr_red_bet_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01660">
        <property type="entry name" value="narH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="178"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="211"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="560" mass="62239" checksum="56A7B0ADC52AB570" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBY1</accession>
    <name>D3QBY1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5236"/>
    <dbReference type="EnsemblBacteria" id="ADD44870">
        <property type="protein sequence ID" value="ADD44870"/>
        <property type="gene ID" value="Snas_5236"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5236"/>
    <dbReference type="HOGENOM" id="CLU_905876_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032724">
        <property type="entry name" value="DddA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14428">
        <property type="entry name" value="SCP1201-deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="307" mass="32971" checksum="07DCF38201D77A7C" modified="2010-04-20" version="1">MASIEELIAAVRSALSTVAEGRTLTTQGCSALIEGTAALTGISRGSTNYQLRTALEALTAAIQAAERAESVEATVLEAIDAYVTEISKGSRPFDLPTLLAKLKNQGVVGLEGRTLEQVPDFDPTRTNPACFQGLAPRQDGGPTRGNLFYSDGRRWNTEPLESSGGASAFDLDKVKLEYRDVTPAQGHLEGNVAAWMADNQERETEMAPLPTPGTTEFSKELVTLTETAYNYFAHPVTVDPRVNRTLIAVYNNSEEQEEDLLALLASVGLHPPAVPDGHVVAGLVVTRFGDDLNNPVLAWDVYGPDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTW6</accession>
    <name>D3PTW6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9 10">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dnaA</name>
        <name evidence="15" type="ordered locus">Snas_0001</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 11">Belongs to the DnaA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015295.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="SMR" id="D3PTW6"/>
    <dbReference type="STRING" id="446470.Snas_0001"/>
    <dbReference type="EnsemblBacteria" id="ADD39724">
        <property type="protein sequence ID" value="ADD39724"/>
        <property type="gene ID" value="Snas_0001"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0001"/>
    <dbReference type="eggNOG" id="COG0593">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026910_2_0_11"/>
    <dbReference type="OMA" id="ATHIERN"/>
    <dbReference type="OrthoDB" id="219876at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00377">
        <property type="entry name" value="DnaA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018312">
        <property type="entry name" value="Chromosome_initiator_DnaA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038454">
        <property type="entry name" value="DnaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00362">
        <property type="entry name" value="DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01008">
        <property type="entry name" value="DNAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="13">
        <location>
            <begin position="258"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_DnaA_C" evidence="14">
        <location>
            <begin position="470"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="74"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="130"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="74"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="164"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="266"/>
            <end position="273"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD39724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="566" mass="62509" checksum="72C130FCAA20E959" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU40</accession>
    <name>D3PU40_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-quinone oxidoreductase subunit D</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NADH dehydrogenase I subunit D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nuoD</name>
        <name evidence="8" type="ordered locus">Snas_1277</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016557.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1277"/>
    <dbReference type="EnsemblBacteria" id="ADD40986">
        <property type="protein sequence ID" value="ADD40986"/>
        <property type="gene ID" value="Snas_1277"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1277"/>
    <dbReference type="eggNOG" id="COG0649">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015134_1_2_11"/>
    <dbReference type="OMA" id="IMGTSME"/>
    <dbReference type="OrthoDB" id="473681at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014029">
        <property type="entry name" value="NADH_UbQ_OxRdtase_49kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="PTHR11993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01962">
        <property type="entry name" value="NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00535">
        <property type="entry name" value="COMPLEX1_49K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5" id="KW-0874">Quinone</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 5 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Complex1_49kDa" evidence="7">
        <location>
            <begin position="159"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="444" mass="49125" checksum="D4291F7CA1332C67" modified="2010-04-20" version="1">MTTKEETTDAYADARDTTEGKVFTVTGGDWDSVIGGHDPVSDERLVVNMGPQHPSTHGVLRLVVEMEGETVRELRPVIGYLHTGIEKNTEYRTWTQGTTFVTRADYLAPIFNETAYCLAVEKLLGIEPPQRATTIRVIMMELNRIASHLVGLATTGMELGALSMMIYGFREREYILDIFEAVSGLRMNMAYVRPGGVAQDMPDEAVTKIRDFLKYMPGCINDYEKLLSGNPIWQERTQDIAYLDVSGCLAMGVTGPVLRAAGLPWDLRKTMPYCGYEDYDFEVATHTGADVWGRYLVRLEEMRQSLRIVEQALERLEPGPVMVEDKKIAWPAQLSLGGDGMGNSLAHVRKIMGQSMESLIHHFKLVTEGFRVPPGQVYVPIEAPRGELGIHLVSDGGTRPYRMHMREPSFVNLQAVPALAEGGLLADVIAGGASLDPVMGGCDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUE0</accession>
    <name>D3PUE0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018524.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3284"/>
    <dbReference type="EnsemblBacteria" id="ADD42953">
        <property type="protein sequence ID" value="ADD42953"/>
        <property type="gene ID" value="Snas_3284"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3284"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="GYEVLQY"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="319" mass="34525" checksum="1D231254AB7FD145" modified="2010-04-20" version="1">METYRLAGTDLTVSKLCLGAMALGAVQDERTSFAILDRFVEAGGTFIDTANNYMFWLDGHTGDESELMLGRWLAARGNREDVVVASKVGWRPTTVGGGLDDAEHLTAQRIGAAIDESLARLGTDYLDLYWTHRDDRDVGLAETVAGMAATVTAGKARAIGASNHTAWRVSEARALAPDTVRYVAMQNRYSYLQPRPGVKLAESGHVHATSDTLDFVAATEDMALLTYTALLYGSYTRDDKPLSPQYVHPGTEARLQVLDEVATETGATRNQVVLAWLCGHPGPVIPLVGVSSVSQLDEVIDGVNLKLSAEQWRRLSDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUK3</accession>
    <name>D3PUK3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Hydrogenobyrinate a,c-diamide synthase</fullName>
            <ecNumber evidence="3">6.3.5.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Hydrogenobyrinic acid a,c-diamide synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cobB</name>
        <name evidence="6" type="ordered locus">Snas_3350</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2 ATP + 2 H2O + hydrogenobyrinate + 2 L-glutamine = 2 ADP + 2 H(+) + hydrogenobyrinate a,c-diamide + 2 L-glutamate + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:12544"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:77873"/>
            <dbReference type="ChEBI" id="CHEBI:77874"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from precorrin-2 (aerobic route): step 9/10.</text>
    </comment>
    <comment type="domain">
        <text evidence="3">Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="3">The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CobB/CbiA family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.9" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018587.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3350"/>
    <dbReference type="EnsemblBacteria" id="ADD43016">
        <property type="protein sequence ID" value="ADD43016"/>
        <property type="gene ID" value="Snas_3350"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3350"/>
    <dbReference type="eggNOG" id="COG1797">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022752_2_0_11"/>
    <dbReference type="OMA" id="PANTRMT"/>
    <dbReference type="OrthoDB" id="692368at2"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042242">
        <property type="term" value="F:cobyrinic acid a,c-diamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043802">
        <property type="term" value="F:hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00027">
        <property type="entry name" value="CobB_CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004484">
        <property type="entry name" value="CbiA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873">
        <property type="entry name" value="PTHR43873"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00379">
        <property type="entry name" value="cobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="4">
        <location>
            <begin position="8"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="GATase_3" evidence="5">
        <location>
            <begin position="251"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <feature type="site" description="Increases nucleophilicity of active site Cys" evidence="3">
        <location>
            <position position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="461" mass="49554" checksum="DAEFF8F6E95F3409" modified="2010-04-20" version="1">MPRRAGFVVAASHSGAGKTTVTAIVLRRLCQRGLAVRSFKIGPDFIDPGYHREITGRPSINLDVWMMGVAGVRRAFRRWSQDAEVSVVEAMGGLYDGMNGTGRGSAAHVAKTLGLPVVVVLDVWGMTGTTGAILEGLRSFDRGVRIAGCILNRVGSRTHADMIVDALPRRLKPLVLGAITQDQSLAVQERHLGLVTVDENRASERDRGLAQDEAGAELDIERLLTVTRGGAAVESASVKLGRLRGQPRVRLAVARDAAFCFYYEENLVALREAGFELVSFSPVRGDGLPDGTDAVYLGGGYPERFAVELGANRGLARQLRERAQEGMPVYAECGGMMYLARSLTGFDGVRHRMAGVLPIDVAMDSGYLSIHYVRVRTRVASPFGDGGVEALGQEFHQSRVTAADVEPNLFDVSTSTGASYRAGYLVGNVAASYVHLHLAGRSRMLRQWVRCAEGAGRGVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUU0</accession>
    <name>D3PUU0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative phytochrome sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5330</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CdaR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5330"/>
    <dbReference type="EnsemblBacteria" id="ADD44964">
        <property type="protein sequence ID" value="ADD44964"/>
        <property type="gene ID" value="Snas_5330"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5330"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017436_0_0_11"/>
    <dbReference type="OMA" id="MSPARTK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041522">
        <property type="entry name" value="CdaR_GGDEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17853">
        <property type="entry name" value="GGDEF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="3">
        <location>
            <begin position="76"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="627" mass="66659" checksum="B8E20A0C75E9E0EE" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUU3</accession>
    <name>D3PUU3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020538.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5333"/>
    <dbReference type="EnsemblBacteria" id="ADD44967">
        <property type="protein sequence ID" value="ADD44967"/>
        <property type="gene ID" value="Snas_5333"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5333"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_38_0_11"/>
    <dbReference type="OMA" id="DERQHAP"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="216" mass="22855" checksum="24EA2A6BDAD31C23" modified="2010-04-20" version="1">MTRSPARGRRADAVRSETAILDAAVRLLNVNPDTGLETIAAEAGVTRQTVYAHFPSRDRLLAAVVERITEDVVAAIDATGLEDGSATEALFRLLEASTAAANRYPVLRKALASVAVPTADDERQHAPITERITKVIARGQAAGEFDATLPPHWFATVTIELSHAAAHEVDNGRMPEARMSEALRVTLLRALGAALSQRSVGLHGDAAPPGSPAACR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUV3</accession>
    <name>D3PUV3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5343</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5343"/>
    <dbReference type="EnsemblBacteria" id="ADD44977">
        <property type="protein sequence ID" value="ADD44977"/>
        <property type="gene ID" value="Snas_5343"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5343"/>
    <dbReference type="eggNOG" id="COG2374">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003608_1_0_11"/>
    <dbReference type="OMA" id="HPREAND"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001322">
        <property type="entry name" value="Lamin_tail_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036415">
        <property type="entry name" value="Lamin_tail_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00932">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74853">
        <property type="entry name" value="SSF74853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51841">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048377" evidence="2">
        <location>
            <begin position="34"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="domain" description="LTD" evidence="3">
        <location>
            <begin position="27"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="940" mass="96305" checksum="DF356DC665728768" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV07</accession>
    <name>D3PV07_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5399</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020602.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5399"/>
    <dbReference type="EnsemblBacteria" id="ADD45031">
        <property type="protein sequence ID" value="ADD45031"/>
        <property type="gene ID" value="Snas_5399"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5399"/>
    <dbReference type="eggNOG" id="ENOG5031GJC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030181_0_0_11"/>
    <dbReference type="OMA" id="CARRCEF"/>
    <dbReference type="OrthoDB" id="2064731at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025447">
        <property type="entry name" value="DUF4192"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13830">
        <property type="entry name" value="DUF4192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="328" mass="34600" checksum="5DAF090B1452ADB7" modified="2010-04-20" version="1">MNTTSSADITLSSPADLVAAIPHLVGYRPTDSAVLVGLDEGHIKVTLRADLPLASGCFDVFADVITTMRRNDATAVVLVGFGEAARVTPVVDHLLPRLHGADIEVLDAIRVTGGTFWSYVCPEPTCCPPEGKPVPRDSRIEAAFVGEGMVAAPDRNAVAAQIDPVDFETRNHVALHLCDFKRTARLDRLVNAKRDRAAENTAKLAGAAKGVEAGTMPGLALTAKLGWAIAETSTGYKTALAIVDAGDHAHGLALWIWLARHHTGIYRSRAAAMTAYAAWRRGNGVLAGEAVGVALRLQPTCRLAQAVGLALSNGFPPAKVPPFSEVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV08</accession>
    <name>D3PV08_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Single-strand binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020603.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5400"/>
    <dbReference type="EnsemblBacteria" id="ADD45032">
        <property type="protein sequence ID" value="ADD45032"/>
        <property type="gene ID" value="Snas_5400"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5400"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_0_2_11"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="155" mass="17365" checksum="D05CD4F2A6D5A6E5" modified="2010-04-20" version="1">MIHSHLIEGRLAFPPELRYTPNGNQVATMRLLFNDSYRDKSGNWKNGKTRSLDVTCWRELAERVVELNKGDLVLVELGNDLFARTNGQYTNISASAQNVFVSMRYDGASSHREPKPDSERIVTTADGETYSADKWAQLNEADAETESEAAEPVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV25</accession>
    <name>D3PV25_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="2">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">clpP</name>
        <name evidence="5" type="ordered locus">Snas_1371</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 4">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016649.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1371"/>
    <dbReference type="MEROPS" id="S14.009"/>
    <dbReference type="EnsemblBacteria" id="ADD41078">
        <property type="protein sequence ID" value="ADD41078"/>
        <property type="gene ID" value="Snas_1371"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1371"/>
    <dbReference type="eggNOG" id="COG0740">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058707_3_2_11"/>
    <dbReference type="OMA" id="GFKRQDP"/>
    <dbReference type="OrthoDB" id="1728970at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <feature type="active site" evidence="3">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="210" mass="23691" checksum="4AF23684D2E5FE71" modified="2010-04-20" version="1">MNFDFNARYIVPSYTEKTSYGVKEMNPYNKLFENRTIFLGSPVDDTSANDIMSQLLVLEGDDPERDIEMYINSPGGSLTALMAIYDTMQYVRPDIRTVCMGQAASAAAILLAAGAKGKRLALPNSRVIIHQPATEGTYGQASDMEIQAREIMRMRDQMEKVLARHTGQELDKVRRDIERDKILNADEAKEYGIVDTVMEYRKKNQLPQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV78</accession>
    <name>D3PV78_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exonuclease RNase T and DNA polymerase III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1425"/>
    <dbReference type="EnsemblBacteria" id="ADD41131">
        <property type="protein sequence ID" value="ADD41131"/>
        <property type="gene ID" value="Snas_1425"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1425"/>
    <dbReference type="eggNOG" id="COG1949">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064761_3_0_11"/>
    <dbReference type="OMA" id="AFFHYRN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06135">
        <property type="entry name" value="Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022894">
        <property type="entry name" value="Oligoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11046">
        <property type="entry name" value="PTHR11046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="1">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="191" mass="21271" checksum="9B90EBF82A7CE098" modified="2010-04-20" version="1">MWIDCEMTGLDLQRDALIEIAVLVTDAELRVLDEGLDIVIHTEQSVLDGMVDVVKEMHGSSGLTQEVAAATTTVAEAEKRVLEYVRGHVPQPGTAPLCGNSIATDRGFLARDMPALNNHLHYRMIDVSSVKELTRRWYPRVYFAQPPKCMAHRALADIKESIRELEYYRRAVFVPQPGPDVDEATAIAEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV80</accession>
    <name>D3PV80_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NLP/P60 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1427</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016704.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1427"/>
    <dbReference type="MEROPS" id="C40.007"/>
    <dbReference type="EnsemblBacteria" id="ADD41133">
        <property type="protein sequence ID" value="ADD41133"/>
        <property type="gene ID" value="Snas_1427"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1427"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034085_1_0_11"/>
    <dbReference type="OMA" id="PVHRRSQ"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049488" evidence="3">
        <location>
            <begin position="45"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="4">
        <location>
            <begin position="187"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="301" mass="31417" checksum="E6E2882AAEEB4306" modified="2010-04-20" version="1">MPAVYPESNGDSPSSRKLIRSLVGTGLTAAVIAIAVALPDQAAAKPSLEDKLKTVSSELKDAKSDLADLKERRSDVKGEARTAQAKLDEAPEAVTEAVAAVDDATSPIDRLSVLSGYGSSQTAELAEAVGDRAEAAEQTKRLSGDIDDLEDKVDDLTDKRDKLKNKLAEAASESGSGKSGDDSPSVSSDGAGAVAFAKAQLGDAYVFGSTGPDTWDCSSLTQAAWSAAGKSIGRDTYAQWDNMTHIDRADLSPGDLVFYNSQGHVAMYVGGGKVIHAPQEGETVKYSPIDMMPIDGYTTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVQ6</accession>
    <name>D3PVQ6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, RpiR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3507"/>
    <dbReference type="EnsemblBacteria" id="ADD43170">
        <property type="protein sequence ID" value="ADD43170"/>
        <property type="gene ID" value="Snas_3507"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3507"/>
    <dbReference type="eggNOG" id="COG1737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055769_1_2_11"/>
    <dbReference type="OMA" id="VPFIHRS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05013">
        <property type="entry name" value="SIS_RpiR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000281">
        <property type="entry name" value="HTH_RpiR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035472">
        <property type="entry name" value="RpiR-like_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01418">
        <property type="entry name" value="HTH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51071">
        <property type="entry name" value="HTH_RPIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH rpiR-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="136"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="342" mass="37238" checksum="AF2F29B0D52F9B89" modified="2010-04-20" version="1">MCPTERADPRTVLVRVRAALPGLRPSERRIAEAILDDPHATAGLTVAELAAACDTSTTTVVRFYQRIGYGRYKDLRLDLTREATREQLETANLPAASGDIDRDDTIDDIIAKVAANETLSIADTAEILDRDALARAVDCVLNARRVDSFGVGASGFVGLDLQQKLTRIGRTALSWLDTDAAWSAAVTLDEQCVAIAISHTGTTAATVEFLAMAAAEGATTIAITNHDNTALAETADVVLTTAARETRFRSGALGSRIAQLMVVDCLFTGVARASYDASMSALRKTYAAVHRKGRGQRLYRRIVIRRRRPGSHWVRAYPRWRATDRTHRARGPPQRGEPTRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-04-07" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW35</accession>
    <name>D3PW35_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5525</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5525"/>
    <dbReference type="EnsemblBacteria" id="ADD45156">
        <property type="protein sequence ID" value="ADD45156"/>
        <property type="gene ID" value="Snas_5525"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5525"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_11"/>
    <dbReference type="OMA" id="LAEVWDW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="12"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="138"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="138"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="234" mass="25560" checksum="F6877B6BE824EB92" modified="2010-04-20" version="1">MTANRPSEQGRRILVVEDEPTIAASVAARLRSEGHRVEIAADGPAAVAADAAFLPDLIVLDVMLPGFDGLEVCRRVQARRPVPVLILTARDDETDMLVGLGVGADDYLTKPFSMRELTARVSALLRRVDRLSAPPPAEPVLRFGDLRVDRAARLVHRGDEEVHLTATEFDLLVYLTEHPQAVLSREQLLAQVWKWADGGGTRTVDSHVKALRRKLGAEVIRTVHGVGYAWAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW92</accession>
    <name>D3PW92_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease PH</fullName>
            <shortName evidence="4">RNase PH</shortName>
            <ecNumber evidence="4">2.7.7.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA nucleotidyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rph</name>
        <name evidence="7" type="ordered locus">Snas_1546</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>phosphate + tRNA(n+1) = a ribonucleoside 5'-diphosphate + tRNA(n)</text>
            <dbReference type="Rhea" id="RHEA:10628"/>
            <dbReference type="Rhea" id="RHEA-COMP:17343"/>
            <dbReference type="Rhea" id="RHEA-COMP:17344"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:173114"/>
            <dbReference type="EC" id="2.7.7.56"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homohexameric ring arranged as a trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.56" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016820.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1546"/>
    <dbReference type="EnsemblBacteria" id="ADD41249">
        <property type="protein sequence ID" value="ADD41249"/>
        <property type="gene ID" value="Snas_1546"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1546"/>
    <dbReference type="eggNOG" id="COG0689">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050858_0_0_11"/>
    <dbReference type="OMA" id="KGKGQGW"/>
    <dbReference type="OrthoDB" id="1824064at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009022">
        <property type="term" value="F:tRNA nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11362">
        <property type="entry name" value="RNase_PH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00564">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002381">
        <property type="entry name" value="RNase_PH_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018336">
        <property type="entry name" value="RNase_PH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01966">
        <property type="entry name" value="RNasePH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01277">
        <property type="entry name" value="RIBONUCLEASE_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="RNase_PH" evidence="5">
        <location>
            <begin position="12"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="RNase_PH_C" evidence="6">
        <location>
            <begin position="162"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate (substrate) binding" evidence="4">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <note>substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="241" mass="25809" checksum="8C0CADA8047300AE" modified="2010-04-20" version="1">MSRPDNRAPDALRPVKFQRGWTKHPEGSVLVEFGDTRVLCTASVDTGVPRWRRGSGSGWVTAEYSMLPRATNTRGDREAVKGKIGGRTHEISRLIGRALRSCLDLKALGENTITIDCDVLQADGGTRTAAITGSYVALQDAVTWLTDKKMARKPDKILTRSVAAVSVGVVGGTPVLDLNYVEDSSADVDMNVVCTGDGDFVEVQGTGEEAVFDRSTLDALLDLATKGCKELTGAQVRALLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWF6</accession>
    <name>D3PWF6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016884.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1610"/>
    <dbReference type="EnsemblBacteria" id="ADD41313">
        <property type="protein sequence ID" value="ADD41313"/>
        <property type="gene ID" value="Snas_1610"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1610"/>
    <dbReference type="eggNOG" id="COG3599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017257_1_0_11"/>
    <dbReference type="OMA" id="LHLETQT"/>
    <dbReference type="OrthoDB" id="937807at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019933">
        <property type="entry name" value="DivIVA_domain"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03544">
        <property type="entry name" value="DivI1A_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="346"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="42"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="408" mass="45264" checksum="56C809F26C763693" modified="2010-04-20" version="1">MSQQPSNSFFDKSTTQPEFANVLRGYDRNQVDDFVQRVNAALSQIDNARGEAEARMTDAQRRLRQAEQRVTGLEQKLAEQAQQLEENSRPTLSGLGTRVEQILRLAEEQANEHRAEAKRETEGILSSARLEAREITDAAREEANGLKQAAEREAGNVRTAAEREAAELRVQARREAETLRADAERDTKQLRTSTGHEVAELKASVEREVASLRATADREITQLRAKAAKDAEEKRAEAAKLFADAKEKRDKELQALDLEIAERREKAEREESQRHAEAIAATQKLVSEAESRARTAEERAKEIETAAETRKVESEKYAQQTTEKAKNAADKALSEAKAEATRLVADAKAEAERTTTKARKEVDKLTRERDSVQSTLRNMMANLQGIGLSAGGDAAAAEEKKDSEVSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWK6</accession>
    <name>D3PWK6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3566"/>
    <dbReference type="EnsemblBacteria" id="ADD43228">
        <property type="protein sequence ID" value="ADD43228"/>
        <property type="gene ID" value="Snas_3566"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3566"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063440_4_0_11"/>
    <dbReference type="OMA" id="MHDIKER"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="8"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="109" mass="11758" checksum="EE1366A30EA79448" modified="2010-04-20" version="1">MQEPTFLILASLAEQALHGYGVIQAVAKLSDNRVKLPPGTLYGALERLTGQGLVAADREEVTDGRLRRYYRLTDEGAEVLSHEARRLSSNAEAAMAGLRRGGRTGLAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWN4</accession>
    <name>D3PWN4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3596</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3596"/>
    <dbReference type="EnsemblBacteria" id="ADD43256">
        <property type="protein sequence ID" value="ADD43256"/>
        <property type="gene ID" value="Snas_3596"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3596"/>
    <dbReference type="HOGENOM" id="CLU_2289940_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="101" mass="11105" checksum="00133911D6231890" modified="2010-04-20" version="1">MQLNCGVASPSQTQITCAFRFLAMERGRPDRRQPVDARTGLAKATDDVVDTDKCPVDNVELERLQFEARRGDPDKEFAGGYIAAYGDQVCELKAVAFAALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWU0</accession>
    <name>D3PWU0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45164">
        <property type="protein sequence ID" value="ADD45164"/>
        <property type="gene ID" value="Snas_5533"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5533"/>
    <dbReference type="HOGENOM" id="CLU_1030200_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="270" mass="28809" checksum="F3C5B9A23DDA2F59" modified="2010-04-20" version="1">MGAAQPRPGIDAVAVGQSFSDPLVDRQCVGLASTAVQRHHREVVAAFAQRMGVHEAEQFGQRLTMPSTVQFGGQSRLQRRQPTLHPLGTDPLGGATTDAAQRRAGEPGFRVPQQLDRPVRVSPAAGTAHGVLELGHVHDGVAGKPQRVAAAPQQHLASGPGAVELAAQRRDVGAQRVLGAGRGIVPPHPVDEFVDAEHPAVAEQQRRQHRARPGSAQPQFAVTAPGADRAEHVDAQRLWCGHETLRSRIGFRVNAIQGVRDRLTPGLTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWW3</accession>
    <name>D3PWW3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5556</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020758.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5556"/>
    <dbReference type="EnsemblBacteria" id="ADD45187">
        <property type="protein sequence ID" value="ADD45187"/>
        <property type="gene ID" value="Snas_5556"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5556"/>
    <dbReference type="eggNOG" id="COG1167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_0_0_11"/>
    <dbReference type="OMA" id="AMSPYRH"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="88"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="311" mass="34240" checksum="6BD068D12DD9DAB3" modified="2010-04-20" version="1">MSKSPPYQKIVTEIKRRIEIGELSVGDRVPSTRAIVEEWGVAIATATKALTTLRTEGIVQATPRVGTVVARPPARPSRRRVLDTAEGTPIRQQIVAAAITMADAEGIAALSMRSVAAQTGMATMTLYRYVNGKDDLVFHMIDTVFADVADRDYDGEDWRARLEAIARRLWRLFQRHPWLPHVVSLGRAQPVPGLIGYADRVLDALRDAKLSPLDKLRVHISLYGLIQGLSASLEQEAQNEEETGMGSEEWMSDAEPQLGDLMASGRFPAFREVIADLEFEYDHDLDALFEFGLASMLDGVAAKLTNPVAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWW9</accession>
    <name>D3PWW9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5562</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020764.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45193">
        <property type="protein sequence ID" value="ADD45193"/>
        <property type="gene ID" value="Snas_5562"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5562"/>
    <dbReference type="eggNOG" id="COG1514">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1193085_0_0_11"/>
    <dbReference type="OMA" id="MARSTWH"/>
    <dbReference type="OrthoDB" id="1896426at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="224" mass="24603" checksum="BBF317F64683F6A0" modified="2010-04-20" version="1">MSRNQEHYDRSRAALLAGELHIDTPPYDGGSRYGISAVLRPTGELARELERWGEDIAAIAGPGHWLLGAGAVHTTLRALEPHSTRSFDGDERFVDYVAALDEAVSGFPPVELELRGFGPHPGGVVVYGHCGAETLPALRRRYVEALDARAVVHHEAGMVRDLWYCSLVQFAAPVTDVAALLAWGEANRDRFVGTAVYREVDILRWRLRGGRLVTETLHTAKLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWY2</accession>
    <name>D3PWY2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5575</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020777.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5575"/>
    <dbReference type="EnsemblBacteria" id="ADD45206">
        <property type="protein sequence ID" value="ADD45206"/>
        <property type="gene ID" value="Snas_5575"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5575"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="YLNWRWC"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="17"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="469" mass="47987" checksum="2612C3598A0D7C50" modified="2010-04-20" version="1">MVEANPTTAPPRQRWLTLPVVSAAQLLVVLDGTIVNIALPSAQRALDMTDANRHWVITAYLLAFGGLLLLGGRVSGALGHRRAFLIGLTGFALASALGGMASEPWILFAARALQGAFAALLAPAGLALLATTFTGERERGRAFGVFAAVGAAGAAVGLIAGGLLTQYAGWRWCLYINVPIAALAMLGAVRIPRDRPHGGTVDIPGALLSVAGFSALVYGFSRAEALGWTHPLVLALLGGGIVALAIFVRVELRAPHPLLPMRVLRHRGRAGAFTTIALTHVSMFGFFLFMSYHTQTVLDYSPVQAGLTLIVNALAAILGSTVIAGRLHGRVSPATLIVPSLLAIAAGIFVVTRTPARATDVLLPYLTPALLLTGLGLGGIMAATATLATSGIGGHDAGTASATYNASMQLGAALGTPLFNTVTIGAATSLALTESATVATVHGYRTALTVGLGIVLAATAIAAVTTRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX21</accession>
    <name>D3PX21_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020816.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5615"/>
    <dbReference type="EnsemblBacteria" id="ADD45245">
        <property type="protein sequence ID" value="ADD45245"/>
        <property type="gene ID" value="Snas_5615"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5615"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_27_1_11"/>
    <dbReference type="OMA" id="ERIACKP"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="18"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="22756" checksum="E416BD29E4AF5D3C" modified="2010-04-20" version="1">MESQRRRYESLVRTARADETRQRIAHAARELFVSHGWAHTTVREVARRAEVSVPTVYSAYGNKKGLALAVVDSMDLTADPSALVTELADSPPRQQLAAAIGFDCRLFQHSGDLIRLLREAARTEPELADIHRAGPRRGEEALLALVSSWPRGTLRDGLTPQLAVDTYAAVCTPDTYADLTGPRGWTPDDVQRLWTDLLTRELLAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX92</accession>
    <name>D3PX92_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1653"/>
    <dbReference type="EnsemblBacteria" id="ADD41355">
        <property type="protein sequence ID" value="ADD41355"/>
        <property type="gene ID" value="Snas_1653"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1653"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056342_5_2_11"/>
    <dbReference type="OMA" id="EMAHHQG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="30"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="238" mass="25387" checksum="90D4FD75DBF0CD97" modified="2010-04-20" version="1">MDIGAVHNSSVVDFQRVADDVHVLRYPVLDVNCVLVLGRDRALLVDTLSTAGQARELAAAVRRLTSSPVVVVNTHDHFDHWFGNHTIAEQLGAVDFWAHESAIAVDADHAESRAAARRACVKLAPEIADEVGDLELLTPNRPVTDEATIDLGGRSVRLWHPGRAHSHGDLIAFAGSVTIAGDLVEEGAPPSVGSDADAAHWSRVLERLAPMIEGPVIPGHGAIVDAAFVTRQAQQLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXN2</accession>
    <name>D3PXN2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate kinase FGGY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3705</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018933.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3705"/>
    <dbReference type="EnsemblBacteria" id="ADD43362">
        <property type="protein sequence ID" value="ADD43362"/>
        <property type="gene ID" value="Snas_3705"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3705"/>
    <dbReference type="eggNOG" id="COG1070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039395_0_1_11"/>
    <dbReference type="OMA" id="MPDLFNY"/>
    <dbReference type="OrthoDB" id="1619686at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008993">
        <property type="term" value="F:rhamnulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019301">
        <property type="term" value="P:rhamnose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07771">
        <property type="entry name" value="FGGY_RhuK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013449">
        <property type="entry name" value="Rhamnulokinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0684">Rhamnose metabolism</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="2">
        <location>
            <begin position="97"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="3">
        <location>
            <begin position="247"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="470" mass="50266" checksum="E0FDCA6ABF565DB7" modified="2010-04-20" version="1">MTQTVAAVDLGATSGRVMLGHFASGTVNLETVSRFPNGPVDTVDGLHWNVLELYRCVVDGLRLAARARPGSVGVDSWAVDYALLRGGRVLGFPYHYRDSRNQVAAERAHRIVPPERMYRESGLQFLPFNTVYQLVAEQDGGLLDVADRLLLIPDLIGYLLSGEAVTERTNASTTGLIDIASGKWNRRLLSELSIPERILTDVVDPGTSLGPVRSSLGLDADCELVTVGSHDTASAVVAVPAVHDDVAYISSGTWSLVGLELPQPVVTEASRAANFTNEAGVDGRVRFLRNVSGLWLLDEMLRHRRDAGEDVDLAALLDAAAAVDSRDVVLFDTDDPRFLPPGDHASRIVDWCREHDVRPPEGLAELTRAILESLAEAYARTLRQASELSGKAVTTVHIVGGGSRNRLLCQLTADRTGLPVLAGPVEATALGNVLVQARALGIVSGSLEALRALVAASVTPVGYQPGGERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY65</accession>
    <name>D3PY65_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA binding domain protein, excisionase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020965.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5764"/>
    <dbReference type="EnsemblBacteria" id="ADD45394">
        <property type="protein sequence ID" value="ADD45394"/>
        <property type="gene ID" value="Snas_5764"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5764"/>
    <dbReference type="eggNOG" id="COG3311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140176_4_0_11"/>
    <dbReference type="OMA" id="RYRWVMA"/>
    <dbReference type="OrthoDB" id="2076478at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="12"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="69" mass="7791" checksum="E8E1C0CA86B06BBD" modified="2010-04-20" version="1">MSTHSLLEEVKFLTVAEVAELMRVSKMTVYRLVHAGSLAAVRVGRSFRVPEHAVQEYLATTFRDDKRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYA1</accession>
    <name>D3PYA1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017039.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1771"/>
    <dbReference type="EnsemblBacteria" id="ADD41468">
        <property type="protein sequence ID" value="ADD41468"/>
        <property type="gene ID" value="Snas_1771"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1771"/>
    <dbReference type="eggNOG" id="ENOG5030AP1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117181_1_0_11"/>
    <dbReference type="OMA" id="GPVFIHA"/>
    <dbReference type="OrthoDB" id="1833573at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009593">
        <property type="entry name" value="DUF1203"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06718">
        <property type="entry name" value="DUF1203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF034110">
        <property type="entry name" value="DUF1203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="163" mass="18009" checksum="8E5959A82AFAA700" modified="2010-04-20" version="1">MTSTYTIAAIAPHILERLRELDDAGNPPEEHVDPEQPLRCCLRRSRDGERLFLVSYSPLRHWAAETGAKPGPYLEFGPVFIHAEDCGGPAEPGVPTGMLGQRRVCRAYNAEGRIIGGVYVEDDNPTVTSIEDTLAKQFADPATALVHVRAVEYGCFLYEVRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYH6</accession>
    <name>D3PYH6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4129 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1847</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017114.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1847"/>
    <dbReference type="EnsemblBacteria" id="ADD41543">
        <property type="protein sequence ID" value="ADD41543"/>
        <property type="gene ID" value="Snas_1847"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1847"/>
    <dbReference type="HOGENOM" id="CLU_1376800_0_0_11"/>
    <dbReference type="OrthoDB" id="2025313at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025403">
        <property type="entry name" value="DUF4129"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13559">
        <property type="entry name" value="DUF4129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4129" evidence="2">
        <location>
            <begin position="101"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="190" mass="20835" checksum="DED0FAA9FEDB1555" modified="2010-04-20" version="1">MNWWTHPVADIGDWFPGGLYGLGLTVLLIGLAIGLLLQPFGLYRFSHRFAKKDKPKDATDIVVAEPVADEALPELPSDALLARAQQFMATGDYRNAVREWLRVAVRDLVERAVIEHRPGWTVTELARAAGQALPPIAASLDEAARVFSDIWYGGYEANLEAATRMRDLHMTITATVSANPPVATVTMEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYR9</accession>
    <name>D3PYR9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019073.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3846"/>
    <dbReference type="EnsemblBacteria" id="ADD43502">
        <property type="protein sequence ID" value="ADD43502"/>
        <property type="gene ID" value="Snas_3846"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3846"/>
    <dbReference type="eggNOG" id="COG2050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089876_13_2_11"/>
    <dbReference type="OMA" id="TTQVWQI"/>
    <dbReference type="OrthoDB" id="2060970at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="63"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="151" mass="15616" checksum="C9511A26F9091EFE" modified="2010-04-20" version="1">MTDPAESSIFPAEVIKQFADVGVDLVSLFSAGALGERMGIEVTHAEPGRVVGTMPVKGNTQPYGLLHGGASAVLAETLGSVGAMLHAGPKRLAVGVDLNVTHHRAAREGTVTGVATPVHAGRTTTTYEVVISDEDGKRVCTGRITCLIRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ72</accession>
    <name>D3PZ72_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein TerC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021072.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5872"/>
    <dbReference type="EnsemblBacteria" id="ADD45501">
        <property type="protein sequence ID" value="ADD45501"/>
        <property type="gene ID" value="Snas_5872"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5872"/>
    <dbReference type="eggNOG" id="COG0861">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064910_0_0_11"/>
    <dbReference type="OMA" id="CHIQLKK"/>
    <dbReference type="OrthoDB" id="1917125at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="252" mass="27430" checksum="993C4824E25E0A73" modified="2010-04-20" version="1">MELLTSPEVWVSFFTLLILELILGVDNVVFISILTGRLPEEQRPRARFWGLLMALLTRLALLATLSWMVGATANLFKLFGMGFSWRDIILIVGGLFLLVKSVHEIHVRLEGPEPEQGGNGGGGKTAGFTSVIIQIALLDIVFSLDSVITAVGMVDELVVMAAAIVVAIALTLVFAKPIWGFIDRHPTVKMLALSFLVLIGAALIADGFEQHIPKGYVYGPIAFSLLVELLNIRAKKAAAKPVELREPHAKDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZE5</accession>
    <name>D3PZE5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Transposase, IS605 OrfB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Snas_1923</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the transposase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017190.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1923"/>
    <dbReference type="EnsemblBacteria" id="ADD41619">
        <property type="protein sequence ID" value="ADD41619"/>
        <property type="gene ID" value="Snas_1923"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1923"/>
    <dbReference type="eggNOG" id="COG0675">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032903_0_0_11"/>
    <dbReference type="OMA" id="YGIAYIR"/>
    <dbReference type="OrthoDB" id="222391at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="14">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_IS605" evidence="12">
        <location>
            <begin position="179"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="13">
        <location>
            <begin position="299"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="382"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD41619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="425" mass="47227" checksum="3012FA1F62040CD7" modified="2010-04-20" version="1">MQLRYQYRVYPSPGQRMALAKAFGCARLVWNDALALRKRAYQDGVAISPGDVAKRVTTVAKKTPQRAFLSEVSAVVLQQSLRDLDTAYKNFFESVSGKRKGPKAGPPRFKKRASRQSIRVNRNAFSLTQKRRLYVAKVGDLKVRWSRELPAVPSSVTVIKTAAGRYFASFVIEVAAQPLPVLSEDQDTGIDLGLSSFAVLRGRVIASPRFLRQAERRIRKAQRELARKRNGSANRRKTRVKLAKAHARVANRRRDFIEQETTRIVRENQAVYVEDLYVKGMAVRRGRRGKSVGDQALGAFTRTLEAKCARFGRGFAKVGRWFPSTQLCSACGTVEGPKGLAGLKARTWVCGCGAVHDRDANAEHNIRAEGRRVLAEGRSERLNARGAQVRPVPVPAPRVETGTRRGVDRAKAESPAPDTRKEPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZL9</accession>
    <name>D3PZL9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polyprenyl synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1997</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017264.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1997"/>
    <dbReference type="EnsemblBacteria" id="ADD41693">
        <property type="protein sequence ID" value="ADD41693"/>
        <property type="gene ID" value="Snas_1997"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1997"/>
    <dbReference type="eggNOG" id="COG0142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_2_1_11"/>
    <dbReference type="OMA" id="ISYEHRD"/>
    <dbReference type="OrthoDB" id="1861068at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="368" mass="38777" checksum="363D0FD1A7A31DE1" modified="2010-04-20" version="1">MRETDTVQHREAAGAGPVEEVLRRVRELCVPALRAAVAELEAPARRAAEYHFGWVDEAGRRVEANGGKALRPALTLLCAEAAGGQADEAVPAAVAVELVHNFSLLHDDVIDGDRTRRHRATVWAVFGRPTAILAGDSLLSLAFEVLAESRPAGVGVLAEAVTRLNDGQLRDMDLETRVDVSLAECRDMAARKTGALMAAACRLGAESGGADGERAGRFADFGGALGLAFQAADDLLGIWGDAQVTGKPVGSDLVNRKRSLPVTAALAGRAPYAGRLREWYRDGGTGTTPDAVGRPPSSSETGRSDAPTAAEIAEVTGWVERAGGRRWAVAAARRELDAGLAALERAGPLEPAAGRLRALAHHLTFRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZP9</accession>
    <name>D3PZP9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3932</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019157.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3932"/>
    <dbReference type="CAZy" id="CBM35">
        <property type="family name" value="Carbohydrate-Binding Module Family 35"/>
    </dbReference>
    <dbReference type="CAZy" id="GH43">
        <property type="family name" value="Glycoside Hydrolase Family 43"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43586">
        <property type="protein sequence ID" value="ADD43586"/>
        <property type="gene ID" value="Snas_3932"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3932"/>
    <dbReference type="eggNOG" id="COG3507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009397_8_2_11"/>
    <dbReference type="OMA" id="WKNDGNC"/>
    <dbReference type="OrthoDB" id="386120at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CMB_fam6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16990">
        <property type="entry name" value="CBM_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048500" evidence="5">
        <location>
            <begin position="40"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="6">
        <location>
            <begin position="336"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="3">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="456" mass="48249" checksum="35225BE60860F53B" modified="2010-04-20" version="1">MLTNALSFVRSRKLLTLGIAAAIAVSSAAWITLSPDAKAEGADAKAVAPQIVIGGNFPDPDVSKFGDKYYAYATNGGQNLPVATSDKPGGEWAMTGADGLPKLGAWAQPGRTWAPDVSQRPDGSYLLYYTAHSISPDRQCIGAATSAKPEGPFEPVGDKPIVCPADEGGAIDASSFTDGDKHYLIYKTDANAIGKPPVVYLQETSADGVNFIGDRIEILRNDQDAERGILEAPVMVKQGGNYVLFYAGGEYWNDSYFTSYATSTSLTGPFKKAFRPLITGSSVDGAVNGPGGADVVRGSDGVDHIFFHGHVGDGRSVYLADLGWAGDLPVVRGSRVRYEGENGKVNNCKVRDNAAGASQGKVVAYIDHADSYVDIDVYTPSAGNHTVSVGFANGSQEPSSHKVSVNGTEVGAVTYPITGWDNWQQANVDVDLKAGWNTLRFGKGTAFAELDYIEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZZ0</accession>
    <name>D3PZZ0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4025"/>
    <dbReference type="EnsemblBacteria" id="ADD43677">
        <property type="protein sequence ID" value="ADD43677"/>
        <property type="gene ID" value="Snas_4025"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4025"/>
    <dbReference type="eggNOG" id="ENOG5030QZQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076574_0_0_11"/>
    <dbReference type="OMA" id="GEGWPVM"/>
    <dbReference type="OrthoDB" id="1253790at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041273">
        <property type="entry name" value="DUF5596"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041644">
        <property type="entry name" value="GNAT_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18164">
        <property type="entry name" value="GNAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18082">
        <property type="entry name" value="NAT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAT_N" evidence="1">
        <location>
            <begin position="15"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="GNAT_C" evidence="2">
        <location>
            <begin position="140"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="297" mass="33004" checksum="B4E5103A7C5D856C" modified="2010-04-20" version="1">MPLPSAAELDSLLTGRLGCDPIDAAAVAAARPDPDADPELWWVMERCYRHLLADMGGIEMLLWPQLPDKWGATGRFVHLYALLAAIPETLAYNRSRGIEDEITWATLSNVAEKLRLNRARFGVPGLEVAHWFTLHFRGAIHRLGRLEFAPERAGEGFPDVDAGDLVLGVHIPQDGGPMSPDACAASIAWAREFFPHHFGDRFASRPLFVCSSWLLDPKLAEVLRPDANIVAFQKLFELLPAGEDASELGEKDVLRFVFDQVGDTDLASLPRDSTLRRVLAEGFAEPRGWQVRTGWFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q001</accession>
    <name>D3Q001_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Regulator of SigK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Sigma-K anti-sigma factor RskA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5902</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021101.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5902"/>
    <dbReference type="EnsemblBacteria" id="ADD45530">
        <property type="protein sequence ID" value="ADD45530"/>
        <property type="gene ID" value="Snas_5902"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5902"/>
    <dbReference type="eggNOG" id="COG5343">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075802_1_0_11"/>
    <dbReference type="OMA" id="VYQMWLI"/>
    <dbReference type="OrthoDB" id="1740922at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018764">
        <property type="entry name" value="Anti-sigma_K_RskA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10099">
        <property type="entry name" value="RskA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="zf-HC2" evidence="5">
        <location>
            <begin position="3"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00030803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="242" mass="26068" checksum="8D87C7FCC8327B03" modified="2010-04-20" version="1">MTEQAHTLVGAYVLDAVDDTERERVERHLAECVECEREVRELRATTARLAETTATAPPLRLRGEVLSRIRRTRQDPPPERSPQSTLRPRRIPRWRSVAAAVAMTVVVAVVGVGVTVTIMRQQVDAERAQTEQVESVLTAPDAEVSTKESESGGRVTVVSSTSRNEAVVMVSGLRPIDDDHSYQVWLVNDAGQTSAGVMEAGRRSATMLVSGIAGTDLVGVTEEPAGGSPKPTLPLVADVPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q004</accession>
    <name>D3Q004_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxidoreductase molybdopterin binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5905</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021104.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5905"/>
    <dbReference type="EnsemblBacteria" id="ADD45533">
        <property type="protein sequence ID" value="ADD45533"/>
        <property type="gene ID" value="Snas_5905"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5905"/>
    <dbReference type="eggNOG" id="COG2041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_2_0_11"/>
    <dbReference type="OMA" id="NNEFYRI"/>
    <dbReference type="OrthoDB" id="1345710at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048748" evidence="2">
        <location>
            <begin position="35"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidored_molyb" evidence="3">
        <location>
            <begin position="236"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="508" mass="53954" checksum="AFFA0D878AC0C2EC" modified="2010-04-20" version="1">MSTRGRSAVAGLACAAVAIGVAELAAAVVTPASAPVVAVGAAVITFTPEPVKEFAIAVFGVYDKLALVAGIGLILAIIAAVIGVACARRPWIGYGGLAGFGLLGVVAAVTRPGSSPWWALPSLIGVLAAMLALRLVFRRRVALDGPETARPPVPGRDVDRRGVLIGFGVAGVAGLAGWRVGGTDDIERIRSTIELPRARSVGPSAVGKALDVKGITPYLTDTANDGFYRIDTALTLPRIDPGKYRLRIGGRVAEPLSLSYQELLDLPLVEREITLSCVSNEVGGELAGTARWLGVPLKDLLDMVKPDAGADQIVGRSADGWTCGTPTKVCSDGRDAMLAVGMDGEPLPIRHGFPVRMLVPGLYGYVSATKWLVELELSSFDDFDAYWVRRGWDAEAPIKTFSRIDTPTATKRVKPGRTPVAGIAWAQRRGIGAVEVRVDDGDWREAELAPVISTDTWRQWVLAWDATPGRHRLEVRATDESGDTQPEKRVTPFPNGATGWHSVLVNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q027</accession>
    <name>D3Q027_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MDMPI_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021127.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5928"/>
    <dbReference type="EnsemblBacteria" id="ADD45556">
        <property type="protein sequence ID" value="ADD45556"/>
        <property type="gene ID" value="Snas_5928"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5928"/>
    <dbReference type="eggNOG" id="ENOG50314EV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094601_1_0_11"/>
    <dbReference type="OMA" id="WTTIAAE"/>
    <dbReference type="OrthoDB" id="2054078at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="1">
        <location>
            <begin position="15"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="215" mass="23272" checksum="363B86081C2A01A9" modified="2010-04-20" version="1">MKTSEARTGLWPLVHAERAALAKDLAGLTEADWDTPSRCEELTVREVLAHLTAAANLTPLRWLAGVVRCRFDFDKQVAMRLAEHLGSSGAETLARFDRVVASTRKPPLPVVAMLGEVVVHGEDIRGPLGIHSDRPMETLTRVAEFYAGSDLMLPSRKHTRGLRLVATDGPFDSGSGPRVTGGTLALVMAMTGRTAYLDELDGDGVEVLRQRYAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q029</accession>
    <name>D3Q029_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5931</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021129.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5931"/>
    <dbReference type="EnsemblBacteria" id="ADD45558">
        <property type="protein sequence ID" value="ADD45558"/>
        <property type="gene ID" value="Snas_5931"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5931"/>
    <dbReference type="eggNOG" id="COG0738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035309_1_0_11"/>
    <dbReference type="OMA" id="ATGWLGY"/>
    <dbReference type="OrthoDB" id="1809199at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="393" mass="39366" checksum="2A00EA597778F6FF" modified="2010-04-20" version="1">MAGYYFLTGTGTALWGATLPATDARLDLGSGRLGTVLLVLGLGAAVAMPGAGWLADRWDRQRLLRLAALGSAVALAGPALAGSFGWLVAAAAVLGLAMGALNVALTLQVVHIERRFAVGVMSTMHGMWTLGAVLGGLVTTFALRAGADVRLFLGVAGIVLAVVFLVPGKLLGRFDTVAATETGPSGSGGPGFGLLLALGVIGAAAFLTEGAATDWAGIHVRRVLGAEPATASLVYTIFFAAMTVMRFAGDGLRGRLGPALTLRLACLTASAGYGLVLLAPATGSVRVATAAAGWVFAGAGMALVWPVVSSAMGAGAFSGRRLSTVTTISYTGGLIGPAVMGFIASASSLPTALTIPFVLAVAVAVIAPAVVTATIRGRRVDSGVSRSTYEQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q050</accession>
    <name>D3Q050_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021150.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5952"/>
    <dbReference type="EnsemblBacteria" id="ADD45579">
        <property type="protein sequence ID" value="ADD45579"/>
        <property type="gene ID" value="Snas_5952"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5952"/>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_11"/>
    <dbReference type="OMA" id="WRWMWET"/>
    <dbReference type="OrthoDB" id="1261526at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="250" mass="25968" checksum="95739345A68A28B0" modified="2010-04-20" version="1">MSRGIAVVTGASSGIGAATARRLATEGFTVVAAARRADRLQKLAADIGGVAVACDITRQADVDALAEKVASLPGELELLVNNAGGAFGFDYVAESDIDDWRRMYEVNVIGTVQVTKALLPALTASGAGTIVVVSSTAGLGVYEGGGGYTAAKHAETALTGTLRLELCGDPVRVIEIDPGMVKTDEFSLVRNRGDAEAAAKPYAGVAEPLVAEDIADCVAWVATRPHHVNVDRLVVRPLAQAAQHKVHREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q060</accession>
    <name>D3Q060_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5962"/>
    <dbReference type="EnsemblBacteria" id="ADD45589">
        <property type="protein sequence ID" value="ADD45589"/>
        <property type="gene ID" value="Snas_5962"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5962"/>
    <dbReference type="HOGENOM" id="CLU_2977085_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="58" mass="6144" checksum="004C54EBAAA883AB" modified="2010-04-20" version="1">MFVVMGATSVTSLGGWLLAVPLGLVTLAAIGAGMWFLRRSRGRRMLPADRGDSDPLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q087</accession>
    <name>D3Q087_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cysteine desulfurase</fullName>
            <ecNumber evidence="5">2.8.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5990</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5990"/>
    <dbReference type="EnsemblBacteria" id="ADD45616">
        <property type="protein sequence ID" value="ADD45616"/>
        <property type="gene ID" value="Snas_5990"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5990"/>
    <dbReference type="eggNOG" id="COG0520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_0_11"/>
    <dbReference type="OMA" id="LFCAHPL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="4">
        <location>
            <begin position="55"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="467" mass="48377" checksum="A6AD05956973829D" modified="2010-04-20" version="1">MATSTLINRPAAVIPRPRPLAELLPAAANRARELDVVEAPEVPLVDGTSTRYANFDYAASAPCIRAAADAVAELLPRYTAVHRGAGWLSRECTRSYEEARAAVGRFLGCRPDDSVVFTKHTTESLNLLARAVPEGTRVVVFDSEHHANLLPWTDPIRLPVPDSPATAVRSIVSALEVLGDEAPVLVAITGASNVTGELFPIAEVAVAARRFGARVVLDAAQLAPHRAIDIAALGVDYVAISGHKLYAPFGAGVLAGRSDWLDAADPFLAGGGATATVGDATCDITWKTGPARHEAGSPNVIGAVALGAVCEALSNARRSELVAREDALRSRLADGLSAIPGVNQLHIFGPDSDRVGTVAFTIDGLSAGVAAAALSAEYGIGVRDGLFCAHPLTRRLVGRHRTTAPSGCGGGEPASPQALRASIGLGTTEAEVDRLIAAVAELAAAGPAWNYAEVDGRQTPVPDPRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0C4</accession>
    <name>D3Q0C4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0066"/>
    <dbReference type="EnsemblBacteria" id="ADD39788">
        <property type="protein sequence ID" value="ADD39788"/>
        <property type="gene ID" value="Snas_0066"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0066"/>
    <dbReference type="HOGENOM" id="CLU_1805006_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="15892" checksum="96F4C6FD1F91BFA1" modified="2010-04-20" version="1">MGHLINHRETDEAMSLPDGSKGPVDMRTDNVFALAEALRADAERFRTDANRIMREIQGEEGGSRYYGADPRNVPAAQTMNRHDEVRRAAEKLVADVAAGFTGMSRSTRAVIHAFRNQDGLNAAKVRRVRDVLRLPREHGEGPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0E7</accession>
    <name>D3Q0E7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pantothenate synthetase</fullName>
            <shortName evidence="5">PS</shortName>
            <ecNumber evidence="5">6.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pantoate--beta-alanine ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Pantoate-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">panC</name>
        <name evidence="6" type="ordered locus">Snas_0090</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="5">The reaction proceeds by a bi uni uni bi ping pong mechanism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the pantothenate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015382.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0090"/>
    <dbReference type="EnsemblBacteria" id="ADD39811">
        <property type="protein sequence ID" value="ADD39811"/>
        <property type="gene ID" value="Snas_0090"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0090"/>
    <dbReference type="eggNOG" id="COG0414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047148_0_2_11"/>
    <dbReference type="OMA" id="CNHKLEP"/>
    <dbReference type="OrthoDB" id="1661843at2"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004592">
        <property type="term" value="F:pantoate-beta-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00560">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00158">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003721">
        <property type="entry name" value="Pantoate_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042176">
        <property type="entry name" value="Pantoate_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299:SF1">
        <property type="entry name" value="PTHR21299:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02569">
        <property type="entry name" value="Pantoate_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00018">
        <property type="entry name" value="panC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="29"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="146"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>(R)-pantoate</name>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="183"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="273" mass="29172" checksum="1C7ED9D034295A8A" modified="2010-04-20" version="1">MTVRVVATREELAKARAELSGTVALVPTMGALHDGHVANIRAAKARADTVVVSIFVNPLQFGPNEDFEKYPRPLSADLELCAAEGVDLVFAPNREVVYPHEVSVTVDPGPLGEILEGASRPGFFRGVLTVVSKLFHLVRPDFACFGEKDYQQLTLVRRLVSDLDFPLEIVPVPTVRESDGLARSSRNVYLDTEQRAVSLAISRALKAAADSPDPLAAAREVLDAAPGIALDYLALTDPALGPAPETGAARLLIAAKVGTTRLIDNTPVHIGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0R4</accession>
    <name>D3Q0R4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glyco_hydro_114 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017371.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2106"/>
    <dbReference type="EnsemblBacteria" id="ADD41800">
        <property type="protein sequence ID" value="ADD41800"/>
        <property type="gene ID" value="Snas_2106"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2106"/>
    <dbReference type="eggNOG" id="COG2342">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058176_1_0_11"/>
    <dbReference type="OMA" id="DYRFYWK"/>
    <dbReference type="OrthoDB" id="1327691at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004352">
        <property type="entry name" value="GH114_TIM-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016062">
        <property type="entry name" value="TM1410-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35882:SF1">
        <property type="entry name" value="PTHR35882:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03537">
        <property type="entry name" value="Glyco_hydro_114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01545">
        <property type="entry name" value="THEMAYE10DUF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049430" description="Glyco_hydro_114 domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_114" evidence="2">
        <location>
            <begin position="39"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="302" mass="34119" checksum="928772DE5D143448" modified="2010-04-20" version="1">MRGSLVTVAVAVSLLAGCTSAGSPDTESASKSKNDEPTTWVYQLEGYPDGTLDEIVKAPHEAAVIDLARDGGDDYFSKKEITEVKDSGKTTLSYFSMGSIEKYRPEYDDIAASDLMLNRWDDWPDENFVKYWEDEWWDKVVRPRLDLSMEAGFDGAYLDVPNAYEDIDLDLVPGETRESLGRKMTDLIIKISEYTKKREPDFMVLPQNSPELREFDGYMDAIDGLGVEDLFFLDSDKPCTEEWCEENLNNVRAIREAGKLVLSVDYASEESNIEKACEHYAEEDFAGYVSVVELDRIKPPCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q173</accession>
    <name>D3Q173_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6028</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021224.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6028"/>
    <dbReference type="EnsemblBacteria" id="ADD45653">
        <property type="protein sequence ID" value="ADD45653"/>
        <property type="gene ID" value="Snas_6028"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6028"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_11"/>
    <dbReference type="OMA" id="KRLGEPW"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="227" mass="25027" checksum="F2F22514CA5DAFD4" modified="2010-04-20" version="1">MRVLIVEDEPYLAEAVRDGLRLEAIAADIAGDGDTALELLSVNSYDLAVLDRDIPGPSGDEVARWIVDSGSGIPILMLTAADRIDDKATGFELGADDYLTKPFALRELVLRLRALDRRRARSRPPVREIAGLRLDPFRREVFRDGRYIALTRKQFAVLEVLVAAEGGVISAEELLERAWDENADPFTNAVRITVSALRKRLGEPWLIATVPGVGYRIDTGSESDSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q186</accession>
    <name>D3Q186_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_6042</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021237.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6042"/>
    <dbReference type="EnsemblBacteria" id="ADD45666">
        <property type="protein sequence ID" value="ADD45666"/>
        <property type="gene ID" value="Snas_6042"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6042"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_22_1_11"/>
    <dbReference type="OMA" id="MEDATWQ"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="11"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="111"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="289" mass="31879" checksum="3800986228A68EAF" modified="2010-04-20" version="1">MDEKKLLAERFEAHRDHLRAVAYRILGSLAEAEDAVQETWLKAERADTTQVENLGGWLTTVTGRVCLDMLRSKKSRREDSLDDKPTEPVVRVHRRTDPEEEALLADSVGLALLVVLDTLSPVERLAFVLHDMFAVPFADIAPIVERSPETTQRLASRARQRVRGKSVAEDADRSRRHKAVDAFLRAAREGEFEKLLAMLAPDVKFRADEAAARLGGTALLDGARSVAENFNGQAQLARTVLLDGEAGALVAPRGKLLLVLEVRFDGDLISEITAIADSDRLAQMEVSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1D7</accession>
    <name>D3Q1D7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TAP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6093</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021288.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6093"/>
    <dbReference type="EnsemblBacteria" id="ADD45717">
        <property type="protein sequence ID" value="ADD45717"/>
        <property type="gene ID" value="Snas_6093"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6093"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_3_3_11"/>
    <dbReference type="OMA" id="RENTQCA"/>
    <dbReference type="OrthoDB" id="665798at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048794" evidence="2">
        <location>
            <begin position="31"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="86"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="505" mass="54769" checksum="180701C5B37A755E" modified="2010-04-20" version="1">MRRKRRAVGFAVAAALTVAAAVTVTQTAMADPAAEIDWKPCKDADGDVECGTIEVPVDYAKPDGKKIKIGLAKRAATNPEARVGSLMVDPGGPGGSGVDMVKGSKIGSKQLQEKFDFIGFDPRGINTSTQIKCDEEQLAAARSVGVPTTKKKFAKLAKANKKLADGCRKLTGPLFDHADNLHTVEDIESARKALGDEKLNFLGYSYGTLMGQQYAEKYPKNIRSMVLDGNMDHSIESPWEFASTETAAVERNFNSFAKWCDETKDCALYGEDTTKVYGELRDAARAGKLKDPENGDPIDFYAFSERASLINESPAWPEVAKDLKVLRDGKGQLKLDGKAKAEPVEYVFQSMFCSDWDVSIKNFGEWRDITDRLAEEYPNTQWSSYVGTLTSCIGDPVKTTNPQAPLEIDGAPPLVMIGNLNDYATVYEWSEVAAEQSGATLITYEGYGHTIYGRGVECVDKPVESYLIDLEVPDSGLSCESQETPGGGDSGRRSGAPGTGPWAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1I1</accession>
    <name>D3Q1I1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0108</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015400.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0108"/>
    <dbReference type="EnsemblBacteria" id="ADD39829">
        <property type="protein sequence ID" value="ADD39829"/>
        <property type="gene ID" value="Snas_0108"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0108"/>
    <dbReference type="eggNOG" id="ENOG5032VCE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121293_0_0_11"/>
    <dbReference type="OrthoDB" id="1733975at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="167" mass="18743" checksum="662BA47CDABCA197" modified="2010-04-20" version="1">MGILAERLDSLSIETSSPDGQITGVFRPTSALSVHFRDGGYRGYTERGLERQLAALVASAWARYWRARQAAVAEATGEPAVPHQPWDTAGRRYRAERDRTRCEGMSAGHRVHVSHTGLRDWNVVVRDGTLSTLDEFGFAAELESGFTAAMRDHRHKLMMLRDKHLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1J1</accession>
    <name>D3Q1J1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015410.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0118"/>
    <dbReference type="EnsemblBacteria" id="ADD39839">
        <property type="protein sequence ID" value="ADD39839"/>
        <property type="gene ID" value="Snas_0118"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0118"/>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_8_11"/>
    <dbReference type="OMA" id="IAHPAFF"/>
    <dbReference type="OrthoDB" id="1261526at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="242" mass="26156" checksum="9CB820ABC0F4A0E8" modified="2010-04-20" version="1">MTRLDGFKIVVTAAGRDFGRSLAIGLAERGAELFLSARDVAAAERTRAETGHPDRVHAFGCDLSRPDTIAGFAEAVAQRTDHVDVLINNGARYLDGTELTSASDADIAETIASGATGTVLAAKHFLPLLRRSQRPDIVTMVSACADPGHDRSLAHPAFYAAKSAQAGFTEILSRRLRPEGVRVMSLYPPDFDNPDRLSPEWDATPRTAADPLTAQSLIDCVLFAIGQPRDCFLRSLHFEQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1K4</accession>
    <name>D3Q1K4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015423.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0131"/>
    <dbReference type="EnsemblBacteria" id="ADD39852">
        <property type="protein sequence ID" value="ADD39852"/>
        <property type="gene ID" value="Snas_0131"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0131"/>
    <dbReference type="HOGENOM" id="CLU_739458_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="374" mass="37576" checksum="BB9670AE49108A17" modified="2010-04-20" version="1">MASAGRESRGHDRVASLRWSSVATFAARGFVIAGMAGVAWMLGTTTAQAAPEGQTSPDSLVPATSSVFDDAVSTSEQAARSIRSNQLGSGGSSSIDVAESLVSELSEEAGGTLTDAGHNGRGSHHEDKPSGTGTSGTRQNEGADSVHGLVRDLTRPSSLEETVSETTDPLAELTDEVETPVSKMTRAMVTPISDGVDKADESVSGLLDEATDPVSDRDVASVLAPLADSASLTKLIGTGDNGNRQSIHNTLRSADADAGFKAPNTSGNSAVSGTEATENGTSSDTGSALSGAKGGASAPAQLPLSPRPHIPGVFSGGSTTGNGIATDRGATDAGAACIGYAGQVQTAQVSRVRPNMSTMGRPSELIADPAVSPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Y5</accession>
    <name>D3Q2Y5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prephenate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015526.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0236"/>
    <dbReference type="EnsemblBacteria" id="ADD39955">
        <property type="protein sequence ID" value="ADD39955"/>
        <property type="gene ID" value="Snas_0236"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0236"/>
    <dbReference type="eggNOG" id="COG0287">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055968_1_0_11"/>
    <dbReference type="OMA" id="MWRDICL"/>
    <dbReference type="OrthoDB" id="533829at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02153">
        <property type="entry name" value="PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="312" mass="32503" checksum="8F43FB58525BCB73" modified="2010-04-20" version="1">MDIGVVGLGLIGGSLLRRAHAAGFRVSGFDADAATREAARQAGYEVADALAGLADARLLVLAVPLPALATVLPELSGYGGLLTDVTSVKEPVTRLVARHCPSVRFVAGHPMAGKETSGFAAADADLFEGRVWVACLDEDTDLDDWLRLAETACALGARVVPATVAEHDTAAARISHVPHVLAAALSLLAADPLSRALGAGSFADGTRVAQSSPELAAAMCAGNAGPVAAELRRLVEELAEAGNRLGDHDAFRDWYAGARELRVDWPPEPGDVRRLPVTTEDLLSLGRAGGWVTEVDRGTRSVMVRQPQVSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q332</accession>
    <name>D3Q332_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0284</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015573.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0284"/>
    <dbReference type="CAZy" id="GH16">
        <property type="family name" value="Glycoside Hydrolase Family 16"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40002">
        <property type="protein sequence ID" value="ADD40002"/>
        <property type="gene ID" value="Snas_0284"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0284"/>
    <dbReference type="eggNOG" id="COG2273">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019533_0_3_11"/>
    <dbReference type="OrthoDB" id="1046649at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048199" evidence="1">
        <location>
            <begin position="27"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="30"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="256" mass="27996" checksum="1CA6DC9C0523F2DE" modified="2010-04-20" version="1">MSPKWKLLAVAVTATIAVGGGTLAYADSRASWEEQFGGEAGSPPDASRWVQQTGCEWGNGKEEQCYTDGGRNAELDGEGNLVITAKAEEFNDRHFTSARLRATTINDPGTVEVRAKFSGYVAGAWPAIWTTDEANWPTNGELDLMEIGGGGDWKPQYHSHFGTVDDHQQYGDFYPDDSDDPTWTDWHTYRVDYTNGADGEASFYIDDKLAATVPYQVPDDAPAYVILNIAVGGWAGTPDPRLHNTMTVDYVKVTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3C6</accession>
    <name>D3Q3C6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017538.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2278"/>
    <dbReference type="EnsemblBacteria" id="ADD41967">
        <property type="protein sequence ID" value="ADD41967"/>
        <property type="gene ID" value="Snas_2278"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2278"/>
    <dbReference type="eggNOG" id="ENOG502ZWSB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_852354_0_0_11"/>
    <dbReference type="OrthoDB" id="2190287at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="34073" checksum="8AEAB1CFDAC755DA" modified="2010-04-20" version="1">MEPEISAWRNLMELFRCVGESECAWVEQADSGFGLALVLAVALNIGGVVLTWMTLSVVVDFVSRRRSTTIGAATEDGPDFRGVVTVLLGVAASGLWFYLWLGYALPESAGQNYVVWMVTTPLYTLVLMVGPVGVAAAVCGIVGVVVSTYRPSSDATSWTPAARRGVWSVLIVVVTAILVGWRALYEAVPEVAAGPFGRGPQWLQHALEVWTLHEPVAILWELAKLLSTVPGIVGFAALGLLCLVLPAPRGVSGGARGVVNLASATTGAAVTSVVSLVVGTCVVIVVGVLAIAVLALAFLFFAAYVMTYVLVLAVLGAMVTAAVRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3D3</accession>
    <name>D3Q3D3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017545.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2285"/>
    <dbReference type="EnsemblBacteria" id="ADD41974">
        <property type="protein sequence ID" value="ADD41974"/>
        <property type="gene ID" value="Snas_2285"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2285"/>
    <dbReference type="eggNOG" id="ENOG5033AHR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1987966_0_0_11"/>
    <dbReference type="OMA" id="HDAYAED"/>
    <dbReference type="OrthoDB" id="2087567at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013879">
        <property type="entry name" value="DUF1761"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08570">
        <property type="entry name" value="DUF1761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="130" mass="13776" checksum="5C3710142B6251E2" modified="2010-04-20" version="1">MNDMNFWAVLVAAVAAFVLSGAWYAGFGKQLARLSPAYTGEGRSPAVTAVVEIVRNLVLALVVAGLTMFVDIGGWTDAVLLAGAVWIGFPVMILTGSVFHEKVPAKLAAIHAGDWLIKLLAVTLIVGLWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Q8</accession>
    <name>D3Q3Q8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019546.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4328"/>
    <dbReference type="EnsemblBacteria" id="ADD43975">
        <property type="protein sequence ID" value="ADD43975"/>
        <property type="gene ID" value="Snas_4328"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4328"/>
    <dbReference type="HOGENOM" id="CLU_645436_0_0_11"/>
    <dbReference type="OrthoDB" id="2180778at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="425" mass="47610" checksum="522758F7F79F7F68" modified="2010-04-20" version="1">MNNPEIPQWWKTLTSDDSAERLGVNWRDPADWEPPDESASGGTLRNPTTMELDASIREGKLLVGTGPSVNMRGMGLDVDVHWYLDPGQPDQLWCALGFFYDPRLWIPVEPEPAALAEVLSASHPKPALNTVTLTSFTRGFLGFRDEVMLPNVYDGQLVPFNGLDLDRYTTMISYLEHSSWASSHQEDPLHDDFEAVSPLAMSAFDRERNTKSQLLGRVPSMTWRTLHSRSHLSFEVHSRNVVCVGVRYRPSPVSHHAVVKRINEAFKMGYPLDLPLDVVGALTCFDFLTEDDLEHHLTEPESTGHLASAIRVHAALWHGNLRRSLRLREFAAHPEPSVRNAVLRVAADYNYRFLFEEAALVAASDEPAERLEHFLIVGGDPDNYNAFGDSFAGQQPIMVDKEGNPVNVHTDFIGDSDVDEEDEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3W9</accession>
    <name>D3Q3W9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hydrolase_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019607.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4389"/>
    <dbReference type="EnsemblBacteria" id="ADD44036">
        <property type="protein sequence ID" value="ADD44036"/>
        <property type="gene ID" value="Snas_4389"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4389"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062238_0_0_11"/>
    <dbReference type="OMA" id="PLDHPRM"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="28"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="255" mass="27713" checksum="3CB2C29218158B82" modified="2010-04-20" version="1">MSEMELMALTTADGVRLDAMHLPGDRELAIVVAHGFSGSWRHERTRLVSRRLRRFGGVVGFDFRGHGRSRGVSTVGDLEVFDIAAAVAFARSRGYRKVAVVGFSMGASVAVRHAGLHGGVDAVVSVSAAAHWYYRGTRSMRMLHRAIETPSGRTVSRFALRTRISSGGWETVPLTPEEAAPKIAPVPLLVVHGDADRFFPLRHAYALFDAAAEPKQLWIEHGMGHATSGTGPQLVNRVGDWLSNSTRTPAVRPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Z2</accession>
    <name>D3Q3Z2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4413</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019630.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44059">
        <property type="protein sequence ID" value="ADD44059"/>
        <property type="gene ID" value="Snas_4413"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4413"/>
    <dbReference type="eggNOG" id="ENOG502ZHZ7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1785712_0_0_11"/>
    <dbReference type="OrthoDB" id="2145479at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="145" mass="16574" checksum="B23C665CCB77D54C" modified="2010-04-20" version="1">MPSNQLFRETVKAMALGDGAKARELNEQIPDADREAYAIYVAAMFAGAAGHQFEADQSPEAIKRFVNEMRHDFRKADPPFQPLAMEGLFRVLFGEEHLLDEISPADQMRLQFLAIRKIVDQSDHMKQRLDDYLTDAETLAEQWMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q403</accession>
    <name>D3Q403_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_6268</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021459.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6268"/>
    <dbReference type="REBASE" id="24813">
        <property type="entry name" value="M1.SnaDORF6268P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45888">
        <property type="protein sequence ID" value="ADD45888"/>
        <property type="gene ID" value="Snas_6268"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6268"/>
    <dbReference type="eggNOG" id="COG0270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014695_1_0_11"/>
    <dbReference type="OMA" id="FIVKCNH"/>
    <dbReference type="OrthoDB" id="1178320at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0680">Restriction system</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="552" mass="60302" checksum="4E7F28FDEF1CAFA1" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q430</accession>
    <name>D3Q430_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6295"/>
    <dbReference type="EnsemblBacteria" id="ADD45915">
        <property type="protein sequence ID" value="ADD45915"/>
        <property type="gene ID" value="Snas_6295"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6295"/>
    <dbReference type="eggNOG" id="COG1476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_47_3_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="26"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="93" mass="10392" checksum="C9F91A6B0304C104" modified="2010-04-20" version="1">MMVKPRRLNLSTHERASNLAEVAAAVRLRREELGLRQEELADLAGCATRTVSMLEHAKSTLRVDKLIDILTVLGYELVLRPGKSNGQVRVEVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q440</accession>
    <name>D3Q440_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MEMO1 family protein Snas_6306</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the MEMO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021496.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6306"/>
    <dbReference type="EnsemblBacteria" id="ADD45925">
        <property type="protein sequence ID" value="ADD45925"/>
        <property type="gene ID" value="Snas_6306"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6306"/>
    <dbReference type="eggNOG" id="COG1355">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038085_2_0_11"/>
    <dbReference type="OMA" id="EQEAQYG"/>
    <dbReference type="OrthoDB" id="1070303at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07361">
        <property type="entry name" value="MEMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00055">
        <property type="entry name" value="MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002737">
        <property type="entry name" value="MEMO1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060">
        <property type="entry name" value="PTHR11060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01875">
        <property type="entry name" value="Memo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="254" mass="27030" checksum="866F5B034173F912" modified="2010-04-20" version="1">MSDVRPAAVAGRFYPGAAESLRTMIESMVDSIEVPDSDELARAYVVPHAGYRYSGPTAAHVYARLRHHAARVKRVVLVGPSHFVPLQGLATSPAAGWQTPLGTVTTPAAEGIPAEEAPHEREHSLEVQLPFLQVCVGDVEVTPIVVGKSTIEDAATAINGLVDDQTVLLCSTDLSHYHDEETAKRLDRATADAILAAEPRRIKTSDACGVFALRGTVAWAAHHGLSARELNLSTSADTAGTTERVVGYPAFSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4K2</accession>
    <name>D3Q4K2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015733.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0447"/>
    <dbReference type="EnsemblBacteria" id="ADD40162">
        <property type="protein sequence ID" value="ADD40162"/>
        <property type="gene ID" value="Snas_0447"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0447"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1795296_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="144" mass="15077" checksum="5636EB372245BD96" modified="2010-04-20" version="1">MTWPIIEVHAGLRWSLPPLALAALLCAATDSVGSNALGWTVTAAPLAALAHATHWAIRAGSRGWRAIGRVPRPQRITLTAGLGLGASGLTAVIVSVWTASTVLAASGLVAGLALWPVLAYEWAPPPFKKRLLSPLPRLGRPSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4K5</accession>
    <name>D3Q4K5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Microtubule-severing ATPase</fullName>
            <ecNumber evidence="4">3.6.4.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.3" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0450"/>
    <dbReference type="EnsemblBacteria" id="ADD40165">
        <property type="protein sequence ID" value="ADD40165"/>
        <property type="gene ID" value="Snas_0450"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0450"/>
    <dbReference type="eggNOG" id="COG0464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_21_15_11"/>
    <dbReference type="OMA" id="MWIGNSE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="182"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="430" mass="46768" checksum="48559167ECCF86EC" modified="2010-04-20" version="1">MAFARMFMPSADEVAAAVTEDRYSSSMQSPPPLLASLLAAVRAAPDDVPLRVHVSQVLLDHDRAAEALEHCSVVLAREPGNAEALALLRRATAALSGTPEPITDEPATEPEESTGFDWTRAEREVSAETVNPRTDPVTEDIETSTVTLADVAGMEAVKKRLEIAFLGPMRRPDMAAAFGKSTSGGLLLYGPPGCGKTYIARALAGQLRAKFLAVEITDVLDAYVGDRERHIAEVFATARLNAPCVLFFDELDALGQKRSHLRHDSWLRTVVNTLLNEMDSVNSRNDGVFVLGATNHPWDVDSALRRPGRFDRMVLVLPPDRPARLALLNMQLAGRPLGELDVDALAEATGDYSGADLKHLVDSAAELALSDSMVRGEVRPISMDDFGKVLKEVKPSTGPWLDTARNVTAFGNSDGTYDDLRDYLKRRRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q571</accession>
    <name>D3Q571_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zinc metalloprotease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Snas_4475</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4475"/>
    <dbReference type="EnsemblBacteria" id="ADD44120">
        <property type="protein sequence ID" value="ADD44120"/>
        <property type="gene ID" value="Snas_4475"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4475"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1994">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037123_1_0_11"/>
    <dbReference type="OMA" id="ITWVFGG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016483">
        <property type="entry name" value="UCP006404_Pept_M50_CBS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006404">
        <property type="entry name" value="UCP006404_Pept_M50_CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="12">
        <location>
            <begin position="69"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="12">
        <location>
            <begin position="151"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="375"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006404-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006404-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD44120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="400" mass="41867" checksum="2E6CC44261DC8FDB" modified="2010-04-20" version="1">MRTIYSMNQSDGRPTRPGLRIARVLGVPVYISPTWLILAVLVTLIYSDVVRVAVPGLSGGLVYLVSFGFVVTLCGSVFLHELGHALTSRHYGIGVRGITLEMLGGHTEMATDPKSPKVEAVVALAGPAVSAVLGAIGTAVALILEPFTLAWQFAFQVAACNIIVAIYNVLPGMPLDGGRALRALVWAIKGDKHVASIVAGWAGRVVAVATAAAGILAFATGFVSVIGIVFALMIAAVLWLGATRSIQLGTLGARFHLLDVAKLLRPATCVPSGTPLGEALRQQREADSGGVLVVDAAGHPTAIMHSAATQAVPADRRPWVSVDDVAQGLDGSNTWKPSWRGEEVVAAMRRHPANEYAVVDDGRALGVVNAADIADALDPRKPAPAPPRETATDTEVTERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5G0</accession>
    <name>D3Q5G0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Snas_6404</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6404"/>
    <dbReference type="EnsemblBacteria" id="ADD46020">
        <property type="protein sequence ID" value="ADD46020"/>
        <property type="gene ID" value="Snas_6404"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6404"/>
    <dbReference type="eggNOG" id="COG1253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015237_4_0_11"/>
    <dbReference type="OMA" id="PRNEMVS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="4"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="223"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="288"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD46020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="452" mass="48742" checksum="CD25D1EBA5F3DA95" modified="2010-04-20" version="1">MDATLTETVLPLLAFVLLIGANGFFVAAEYALVTVNRPSIDDAASSGDRRARSVQRALKRLSFQLSGAQLGITITALLTGYLAEPALSRLLAPLLKPFGDAAEGVSIAIGMVLANLLSMLFGELLPKNAALARPFPIARATATPQRVFSSVFGWLIHMLNGSANWLVRRFGVEPQEELATARAPDELQLLAAMSARAGTLPRETAMLLQRTLRFGDKRAAEAMTPRVDMVALPTGATIAELIHTAADTGYSRFPVYQDTTDQVVGVAALTDALGLPPARRSVTSVRSVAREPVFVPEHLDLNGLATRMRAEGADMAIVIDEYGGTDGIVTIEDLVEELVGEIADEHDTEPAEETSTRIEATGNLAHLLPGLLHEDEIAEHTGFRMPDGPYETLAGFIMARLGHIPAVGETVVYEGWEFTVVDVERHRVEQVRVQPPPGWEPAGEYVPKEESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q643</accession>
    <name>D3Q643_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">5-hydroxyisourate hydrolase</fullName>
            <shortName evidence="7">HIU hydrolase</shortName>
            <shortName evidence="7">HIUHase</shortName>
            <ecNumber evidence="7">3.5.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_2537</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23736"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="3.5.2.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.17" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017789.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2537"/>
    <dbReference type="EnsemblBacteria" id="ADD42218">
        <property type="protein sequence ID" value="ADD42218"/>
        <property type="gene ID" value="Snas_2537"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2537"/>
    <dbReference type="eggNOG" id="COG2351">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115536_1_0_11"/>
    <dbReference type="OMA" id="SVDPITC"/>
    <dbReference type="OrthoDB" id="1955791at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033971">
        <property type="term" value="F:hydroxyisourate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05822">
        <property type="entry name" value="TLP_HIUase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014306">
        <property type="entry name" value="Hydroxyisourate_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023418">
        <property type="entry name" value="Thyroxine_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000895">
        <property type="entry name" value="Transthyretin/HIU_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023416">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036817">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395">
        <property type="entry name" value="PTHR10395"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00576">
        <property type="entry name" value="Transthyretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00189">
        <property type="entry name" value="TRNSTHYRETIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00095">
        <property type="entry name" value="TR_THY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49472">
        <property type="entry name" value="SSF49472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02962">
        <property type="entry name" value="hdxy_isourate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00768">
        <property type="entry name" value="TRANSTHYRETIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TR_THY" evidence="8">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600895-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="108" mass="12132" checksum="27925018716C9B42" modified="2010-04-20" version="1">MSLSTHVLDATAGKPAAEMGVELWFESEPGEYEQLHVGATDADGRIGGWTVRQGKHRIVFDTGEWWKRRRTPTFHPEVIVSFTVTDPDAHHHVPLLLSPFAYSTYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q680</accession>
    <name>D3Q680_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="4 8">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fmt</name>
        <name evidence="11" type="ordered locus">Snas_2575</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)</text>
            <dbReference type="Rhea" id="RHEA:24380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9952"/>
            <dbReference type="Rhea" id="RHEA-COMP:9953"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:78844"/>
            <dbReference type="EC" id="2.1.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the Fmt family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="4 8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017826.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2575"/>
    <dbReference type="EnsemblBacteria" id="ADD42255">
        <property type="protein sequence ID" value="ADD42255"/>
        <property type="gene ID" value="Snas_2575"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2575"/>
    <dbReference type="eggNOG" id="COG0223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033347_1_1_11"/>
    <dbReference type="OMA" id="CCPVVAY"/>
    <dbReference type="OrthoDB" id="2009156at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08704">
        <property type="entry name" value="Met_tRNA_FMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00182">
        <property type="entry name" value="Formyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005794">
        <property type="entry name" value="Fmt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044135">
        <property type="entry name" value="Met-tRNA-FMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00460">
        <property type="entry name" value="fmt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="9">
        <location>
            <begin position="2"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl_trans_C" evidence="10">
        <location>
            <begin position="203"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Tetrahydrofolate (THF) binding" evidence="8">
        <location>
            <begin position="109"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD42255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="308" mass="32595" checksum="164422F2B263E0A6" modified="2010-04-20" version="1">MRLVFAGTPEVAVPSLQAIADSGHELLAVVTRPDAPSGRGRKLHRSPAGEWADANGVEVLTPAKPREPEFQHRLAELAPDCVPVVAYGALVPQSALDIPRHGWINLHFSLLPAWRGAAPVQHAVLHGDEVTGACVFQLEAGLDTGPIYGSLTETIGAHDTSGDLLTRLADSGAQLLRDVLDSIESGQARAVPQPEHGISMAPKVSVDDARIRWDDPAFAVDRRVRAVTPAPGAWTTWDGQRVRLGPVTPDPQGPALLPGAVAVSKSTVHVGTGTDPVRLGEIQPPGKKRMAADAWGRGLHTSDEIVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6C7</accession>
    <name>D3Q6C7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017873.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2624"/>
    <dbReference type="EnsemblBacteria" id="ADD42302">
        <property type="protein sequence ID" value="ADD42302"/>
        <property type="gene ID" value="Snas_2624"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2624"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_8_3_11"/>
    <dbReference type="OMA" id="FTGWWNE"/>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023765">
        <property type="entry name" value="SBP_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01040">
        <property type="entry name" value="SBP_BACTERIAL_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048900" evidence="1">
        <location>
            <begin position="29"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="80"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="547" mass="60590" checksum="ABBBBE3720014823" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6F8</accession>
    <name>D3Q6F8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">von Willebrand factor type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019772.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4557"/>
    <dbReference type="EnsemblBacteria" id="ADD44201">
        <property type="protein sequence ID" value="ADD44201"/>
        <property type="gene ID" value="Snas_4557"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4557"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_564765_0_0_11"/>
    <dbReference type="OMA" id="YPTGSWG"/>
    <dbReference type="OrthoDB" id="692608at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041176">
        <property type="entry name" value="VWA_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18571">
        <property type="entry name" value="VWA_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="45"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="425" mass="45585" checksum="2C6E47DA455202E3" modified="2010-04-20" version="1">MTGFSIDIDHNEYLSEGDTIVDAIVTVTSAGNGSGTVTADAADFAQVIMVDCSGSMTGSRIAEAKRATIAAIESLDEGCRFAIVKGTDEAQMVYPDDETTAVVKSSTRSAAVKRVQILRAGGGTAMGTWLAKTSRILSGTDAAVKYGLLLTDGRNQHETEEELREHLDDCEGVFTCDACGIGEDWSATEVRHIADTLLGEANGLPEPREWVERFTQLTNGARAKTLADVNLRVFTPARNRIRFVKQMSPHISDLTSRRRELDDKTGDYPTGSWGAEAREFHISVEVPPIQVGDDRLAARVSAMSGDTELIRHMVTARWTGDQMLSTRINPKVALHTGQAELARAIQEGVAAARSGDTDTATDRLGRAVALAAEAGNDNTARLLAKVVEVDPDTGTVQMKSAVSSVDLEMADVESVKTVTVRKSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6H7</accession>
    <name>D3Q6H7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4576"/>
    <dbReference type="EnsemblBacteria" id="ADD44220">
        <property type="protein sequence ID" value="ADD44220"/>
        <property type="gene ID" value="Snas_4576"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4576"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="LACLRWA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="297"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="394" mass="41541" checksum="4805EE29CD853F6F" modified="2010-04-20" version="1">MRRVREFAGKRPVIADVVVAVVVAVVSLPATVGGDTAAGVLEPGTGVVGFGWLWFVAVHVPLTWRRRAPVVVFWTVLGLVAACALAGMTGVFFVFAPLVALYTVARHRSVRRLWPAVAAVAMALGVAAGREPSQWPAIAGVLAVVVAVAACGIAVRVRRALLDERARRAREELERQAKATVASERERLAREVHDIVAHNLAVMVALADGAALTVDASPAEAGDMMGKSAATGREALGELRRLVRVLRDGDGQHRGGEQADVSTEPQAPELEQLVERVREAGLHVELVRDGEPVEREDVEASVYRIVQESLTNVLKHAGAEARARVQLRYEATGVEVTIVDNGAGQAIQARASGGHGLAGIAERAKAHGGEAEAGPVPGGGWQVRVRLPFADGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6H9</accession>
    <name>D3Q6H9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019793.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4578"/>
    <dbReference type="EnsemblBacteria" id="ADD44222">
        <property type="protein sequence ID" value="ADD44222"/>
        <property type="gene ID" value="Snas_4578"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4578"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057862_1_0_11"/>
    <dbReference type="OMA" id="ALDYIGM"/>
    <dbReference type="OrthoDB" id="922937at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041413">
        <property type="entry name" value="MLTR_LBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17765">
        <property type="entry name" value="MLTR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="39"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="293" mass="32517" checksum="615855D0278FAA46" modified="2010-04-20" version="1">MPQAKDDAATLAAFLRARRARVTPADVGLPPGGARRVPGLRREELALLAGVSVDYYTRLEQGRDTHPSAEVLDALARVLRLNEDSRAHLHSLATAPRRRSQRRAAPSVRPSVQRMLDSMRHVPALIVTPYMDVLAFNRLGSALYPGLAELSGRERNVIRMVFLSEAGQDLFPEWQKVTAEAVAFLRAALAPDPHHPRVTELVGELSIHSDEFRRLWARHEVAQKRGGTKTFRHPQVGELTLEWDVFAHLDDGAMLVTYTAVPNSPDEERLMLLSSLAEPEPARAEPVAAPHET</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6N1</accession>
    <name>D3Q6N1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gluconolactonase</fullName>
            <ecNumber evidence="2">3.1.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.17" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019845.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4631"/>
    <dbReference type="EnsemblBacteria" id="ADD44274">
        <property type="protein sequence ID" value="ADD44274"/>
        <property type="gene ID" value="Snas_4631"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4631"/>
    <dbReference type="eggNOG" id="COG3386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036110_0_0_11"/>
    <dbReference type="OMA" id="PAIWAEG"/>
    <dbReference type="OrthoDB" id="966287at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004341">
        <property type="term" value="F:gluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005511">
        <property type="entry name" value="SMP-30"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01790">
        <property type="entry name" value="SMP30FAMILY"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGL" evidence="1">
        <location>
            <begin position="34"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="302" mass="33744" checksum="6C27DAC95727F761" modified="2010-04-20" version="1">MDERIPVVFDSYDERFAGGHGDDYFERLFSGGRWTEGPVYVPSGKYLLFSDIPNNRVLRWDETDGSVSVFRSPSNYTNGHTLDRHGRLISCEQGGRRVTRTEIDGSITVLAERWNGHRLNSPNDAVVASDGSVWFTDPPYGITSDYEGERAEPEIDGCHVYRVDPVSGAVDIVADDFERPNGLAFSPDESLMYIVDTRRNHIRRFRVEPEGKLSGGEVFAECPEGQFDGIRLDETGRIWAACADVHCFDPDGTHLARLRIPEPNVSNLVFGGRKRNRLFVTATGSVYSVLLNINGAAKLPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6R1</accession>
    <name>D3Q6R1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4661</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019875.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4661"/>
    <dbReference type="EnsemblBacteria" id="ADD44304">
        <property type="protein sequence ID" value="ADD44304"/>
        <property type="gene ID" value="Snas_4661"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4661"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="YERRWIA"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="183"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="148"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="380" mass="40789" checksum="B605DC5F3FDF0725" modified="2010-04-20" version="1">MGEGERHQRRWDVIAAGAATAFALAAVIHEMDKKEFWLPVAAAVPLAILTGLALLARRRYPIPVTLFTGSMTVLFIASDSRAGTVALLIALYSLAKYERRWIAIVAGSVVIVVGTVTAGLSGSWEMASRSAPWLVIFLEAGIIAGDIAGRQQRALESARSRAAEAERSKEELAQRRAAEERVRIARELHDSLTHAISVVNVQSSVALHMLNRQPEQAEASLRNIRAASQDAMRELRATLRALRMTEGDSTPGIDSLPALVERSALTIAMDISPDRQALPETVDRTVYRIVQEALTNSTRHARASAVDISIVVDDESVTTTITDDGIGPAPEGVAEGLGLMGMRERVAALGGDLRPGPGPDGGFQVRAVLPLTETEAKELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q768</accession>
    <name>D3Q768_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 7">Transcriptional regulator MraZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraZ</name>
        <name evidence="10" type="ordered locus">Snas_2662</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Forms oligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MraZ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017910.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2662"/>
    <dbReference type="EnsemblBacteria" id="ADD42339">
        <property type="protein sequence ID" value="ADD42339"/>
        <property type="gene ID" value="Snas_2662"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2662"/>
    <dbReference type="eggNOG" id="COG2001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107907_0_5_11"/>
    <dbReference type="OMA" id="RGQERCL"/>
    <dbReference type="OrthoDB" id="1684767at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16321">
        <property type="entry name" value="MraZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16320">
        <property type="entry name" value="MraZ_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01008">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003444">
        <property type="entry name" value="MraZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035644">
        <property type="entry name" value="MraZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020603">
        <property type="entry name" value="MraZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035642">
        <property type="entry name" value="MraZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038619">
        <property type="entry name" value="MraZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34701">
        <property type="entry name" value="PTHR34701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02381">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00242">
        <property type="entry name" value="TIGR00242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="5"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="76"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD42339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="16086" checksum="3A6A50CB6064B2BC" modified="2010-04-20" version="1">MFLGTHTPRLDDKGRLILPAKFRDELAGGLVITKGQERCLYVFPMPEFQRIADELHKAPMTNKAARAYNRVFFASAHDEIPDKQGRVTIPAHLREYAGLDRELVVIGASSRVEIWDAEAWQTYLSDSEEAFADIEEGELPAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7P3</accession>
    <name>D3Q7P3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4743</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019956.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4743"/>
    <dbReference type="EnsemblBacteria" id="ADD44385">
        <property type="protein sequence ID" value="ADD44385"/>
        <property type="gene ID" value="Snas_4743"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4743"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_0_11"/>
    <dbReference type="OMA" id="EAVHEHN"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="213" mass="23341" checksum="3BCED27FFDB68BB6" modified="2010-04-20" version="1">MTTEAKPLRRDAARNRDKLRAAASEVFTAKGLDASLEEIAKHAKVSIGTLYNHFPTREALFDAIFPERVEATEALAREALTADDAWDGFAGYLEGLFDMLAADRGLRHVMTREYPAAEALTEACHRGFAATEAIVLRARESGSLRTDFEMSDLASVLWAMAHIIDTTADVAPGAWRRFLAFILDGLRSEAAHPIAVEAMRPEQIVEALLGPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7T9</accession>
    <name>D3Q7T9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoprenyl transferase</fullName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0732</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016015.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0732"/>
    <dbReference type="EnsemblBacteria" id="ADD40444">
        <property type="protein sequence ID" value="ADD40444"/>
        <property type="gene ID" value="Snas_0732"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0732"/>
    <dbReference type="eggNOG" id="COG0020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038505_2_0_11"/>
    <dbReference type="OMA" id="TKGQPDP"/>
    <dbReference type="OrthoDB" id="1630604at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="34"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="79"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="211"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="256" mass="29185" checksum="F0D4C9711052838D" modified="2010-04-20" version="1">MVLRDLLYKVYEKRLARQLEGKPLPQHVGVMVDGNRRWAKDMGLLNPNDGHREGAEHIKRLLRWCDEMGVGHVTVWLLSTENLSRPAAELDPLLQIIEDLAVELAEEGQPWGLRIVGALDLLPAKHATVIKDAAERTRDRNDGAIINLAICYGGHREIADAVRSLLQEYARGGKTLDEVADLIEEGHIAKHLYLHGQPAPDLLIRTSGEQRLSGFLLWQSAYSEFYFCDMNWPDFRRVDFLRALRSYATRQRRFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7U4</accession>
    <name>D3Q7U4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ADP-ribosylation/Crystallin J1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0737</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0737"/>
    <dbReference type="EnsemblBacteria" id="ADD40449">
        <property type="protein sequence ID" value="ADD40449"/>
        <property type="gene ID" value="Snas_0737"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0737"/>
    <dbReference type="eggNOG" id="COG1397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024566_5_0_11"/>
    <dbReference type="OMA" id="WYADDPE"/>
    <dbReference type="OrthoDB" id="1661477at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005502">
        <property type="entry name" value="Ribosyl_crysJ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036705">
        <property type="entry name" value="Ribosyl_crysJ1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03747">
        <property type="entry name" value="ADP_ribosyl_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101478">
        <property type="entry name" value="SSF101478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="372" mass="40083" checksum="8A7F76AD84A17D07" modified="2010-04-20" version="1">MSMEEKWDAWSDGTTLRLSRSWTGYEIYRARFAPDGDGWAVTELQVETDPSRHRDTVNHPGQFVMLVNSLLLDEDDTLEQFQRADRGLRARASLEGLSVGDALGAQFFVPDNREHYRSQTVPDGLWQWTDDTQMAAVLTTHLCEHDEVRQDELARGFAAEFDLYRGYGPGAARLLRRVRDGEDWRQLSSELFGGNGSFGNGAAMRVAPLGAWFADRGTHQVVEQAALSAEITHSHAEGIAGAVAVAVAAALAAADEVPPPVELLTQVIAATPPGAVRDGLMDARDLPDSTRPEDAARLLGNGSATTAADTVPICAWLAIHNLSDFPAAFWATASVGGDIDTNCAIVGGIVSGHLGSAAIPTEWRSAREPLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7X2</accession>
    <name>D3Q7X2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc D-Ala-D-Ala carboxypeptidase</fullName>
            <ecNumber evidence="4">3.4.17.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0765</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.17.14" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016048.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0765"/>
    <dbReference type="MEROPS" id="M15.001"/>
    <dbReference type="EnsemblBacteria" id="ADD40477">
        <property type="protein sequence ID" value="ADD40477"/>
        <property type="gene ID" value="Snas_0765"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0765"/>
    <dbReference type="eggNOG" id="COG3108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1119635_0_0_11"/>
    <dbReference type="OMA" id="YWSAPTC"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009046">
        <property type="term" value="F:zinc D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013230">
        <property type="entry name" value="Peptidase_M15A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08291">
        <property type="entry name" value="Peptidase_M15_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048932" evidence="1">
        <location>
            <begin position="34"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="55"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M15_3" evidence="3">
        <location>
            <begin position="124"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="263" mass="28146" checksum="216CA440B16439E2" modified="2010-04-20" version="1">MSRLRAIARPRFRLLLVAVVALASMLTAGVVWAESSAQGDGCYTWNRDLASGATGDDVKQLQIRVFGYPEYGKQLAVDGQFGPATTAAVKRFQQAYGLSQTGKGDAATYAKFYELQDDDCTPIHFTYAELNDCNSDWSGGKVSAAEAKANALRVMWSLEAMRHALGDKPITVTSGFRSVQCNNNAGGASDSQHLYGRSADLGAGPHSLCTLAKEARSHGFMGIFGPGYDGHDDHTHADIRSTQAWSAPDCGVRKMAPGAVKHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q836</accession>
    <name>D3Q836_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <shortName evidence="7">GSA</shortName>
            <ecNumber evidence="7">5.4.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-1-semialdehyde aminotransferase</fullName>
            <shortName evidence="7">GSA-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hemL</name>
        <name evidence="9" type="ordered locus">Snas_0829</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0829"/>
    <dbReference type="EnsemblBacteria" id="ADD40541">
        <property type="protein sequence ID" value="ADD40541"/>
        <property type="gene ID" value="Snas_0829"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0829"/>
    <dbReference type="eggNOG" id="COG0001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_1_5_11"/>
    <dbReference type="OMA" id="WGPLIFG"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00713">
        <property type="entry name" value="hemL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="432" mass="44835" checksum="793AE55C135FD58B" modified="2010-04-20" version="1">MSELYDAEAPASEELFERARRVVPGGVNSPVRAFRGVGGTPRFMVRGKGCHMYDADDRRYIDLVSSWGPLILGHAHPAVINALSDAAVAGTSFGTPTPGEVALAEEIVARTPVESVRLVNSGTEATMSALRLARGATGRDLVVKFAGCYHGHVDGLLASAGSGVATLGLPDSPGVPAATAADTIVLPYNDIEAVRTAFAERGADIACVITEAAAGNMGVIAGADDFNKKLYQLCHANGALLILDEVMTGFRVGPGGVADQADLYTYGKVMGGGLPAAAFGGTAEVMNQLAPQGPVYQAGTLSGNPLACAAGLATLRQCTDEVYAHLDSYAERLSAMASQELTKAGVAHRVSAAGNMFSVFFTDAPVRDYTDAAKQDTAAYAAFFHEMLNRGVYLPPSAYEAWFVSAALDEAAMEHIAAALPFAAEAAARVNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8C3</accession>
    <name>D3Q8C3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane-flanked domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2821</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018068.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2821"/>
    <dbReference type="EnsemblBacteria" id="ADD42497">
        <property type="protein sequence ID" value="ADD42497"/>
        <property type="gene ID" value="Snas_2821"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2821"/>
    <dbReference type="eggNOG" id="COG3428">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024617_1_0_11"/>
    <dbReference type="OMA" id="EVMLHPF"/>
    <dbReference type="OrthoDB" id="602555at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014529">
        <property type="entry name" value="UCP026631"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026631">
        <property type="entry name" value="UCP026631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="72"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="426"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="527" mass="56920" checksum="EDB8468EFCFAAB8B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8F0</accession>
    <name>D3Q8F0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2849</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018095.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2849"/>
    <dbReference type="EnsemblBacteria" id="ADD42524">
        <property type="protein sequence ID" value="ADD42524"/>
        <property type="gene ID" value="Snas_2849"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2849"/>
    <dbReference type="eggNOG" id="COG0411">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="SEYAMSI"/>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="247" mass="26458" checksum="D04CBEB47EAE90FB" modified="2010-04-20" version="1">MTLLSVENLSRSYGKLRALDGVVLTVDEGARHALIGCNGAGKTTLLHLLAGTIRASGGRIHYRGKNITRLNPARRARLGIARSFQTPAVFDSLTAFDNLTVAATPHLAGAPWRLASRAAQARDRAEEQIELLGIADCAPRLAGELSHGQRRLVEIGMALVSRPRLLLLDEPAAGLTDTDMERLLEALRQLPTELAVVLVEHHQDLVTEIADTVTVLHEGQILAEGSPEEIAADPQVAEAYLGTGVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8F9</accession>
    <name>D3Q8F9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018104.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2858"/>
    <dbReference type="EnsemblBacteria" id="ADD42533">
        <property type="protein sequence ID" value="ADD42533"/>
        <property type="gene ID" value="Snas_2858"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2858"/>
    <dbReference type="eggNOG" id="COG5563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_737521_0_0_11"/>
    <dbReference type="OrthoDB" id="415763at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="391" mass="40046" checksum="58727937BC61AA49" modified="2010-04-20" version="1">MTKRFGGRWWLVGAITVAVAGLAATTLTVIGSGDSGNGGDSASLSKLDTKTVPPDAGSCDVELLDWPAEGEPGFDLKMSPNGEYIVTDTPGSSDFVMWHNGKLTVVSDVPGEGDASVSGVNSQGVVIGTRSGSDGSTAYEAWRYEDGEASELRGSGGSAVLDLAAVNDEGTIVAAEPAGSSSGDDLYGNGILTWAPGDTEATTVSLSTTTSGRAPTVRDMSNDGTLVGGQFSEEMMDAAGEGDYQARMWDSSGKATAIPIGEYDALASDVAGDWVIASGESNSYRLTTTAKPVPEKLGGFTATAVDTSGRAYGGVVSPTGEDENGDGIDDDPDQHVPGVFDSKARPLPVVEDVKPLHQDVPYGLDIVTAASEDGAKLAGNWKGNPVMWTCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8I6</accession>
    <name>D3Q8I6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018131.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2885"/>
    <dbReference type="EnsemblBacteria" id="ADD42560">
        <property type="protein sequence ID" value="ADD42560"/>
        <property type="gene ID" value="Snas_2885"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2885"/>
    <dbReference type="eggNOG" id="COG0237">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132654_0_0_11"/>
    <dbReference type="OMA" id="RTVDTDY"/>
    <dbReference type="OrthoDB" id="1392851at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="171" mass="18821" checksum="D8293952C8966846" modified="2010-04-20" version="1">MKRVLVTGLSGTGKSTLLEELSRHGFKCVDTDYDGYCGPADGSPPPTPEARPEWIWRPERIDALLSTEDAEVLVVSGCVENQGRFYPRFDHVVLLTVPAAVMAERLRHRDTNDYGKDPGELAESLGYIETVQPLLRQGATLEVDTSAPLAEVVDAVLTHLGQRPDQPRSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8V7</accession>
    <name>D3Q8V7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GMP synthase-Glutamine amidotransferase domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4908</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4908"/>
    <dbReference type="EnsemblBacteria" id="ADD44549">
        <property type="protein sequence ID" value="ADD44549"/>
        <property type="gene ID" value="Snas_4908"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4908"/>
    <dbReference type="eggNOG" id="COG0518">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054974_3_2_11"/>
    <dbReference type="OMA" id="TSMLHWH"/>
    <dbReference type="OrthoDB" id="1242215at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="224" mass="24223" checksum="76BB3020E8A7CD2B" modified="2010-04-20" version="1">MVIENAPTWHLGRLETWLIDAGLEPEVLRPHTGDAIPERVDHHDALIALGGGRGAAWTPELTALLRTTVADRLPLLAFCSSARSLATSFGATTTPVESFNPGPRLIGRRDAAADDPLFGTAPMAIDVIRWRHETLTDLPPDARLLAATPDGEPEIFRIGDRAWGIQSHVEFDGAMVLGLDGDGELARRVDAVTEHLAETWRPIIDRFAALAQGRTASSPLPLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Y2</accession>
    <name>D3Q8Y2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Na(+)/H(+) antiporter NhaA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Sodium/proton antiporter NhaA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">nhaA</name>
        <name evidence="9" type="ordered locus">Snas_0880</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2 H(+)(out) + Na(+)(in) = 2 H(+)(in) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29251"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016162.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0880"/>
    <dbReference type="EnsemblBacteria" id="ADD40591">
        <property type="protein sequence ID" value="ADD40591"/>
        <property type="gene ID" value="Snas_0880"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0880"/>
    <dbReference type="eggNOG" id="COG3004">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015803_0_0_11"/>
    <dbReference type="OMA" id="CLALTHH"/>
    <dbReference type="OrthoDB" id="1805428at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006885">
        <property type="term" value="P:regulation of pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01844">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023171">
        <property type="entry name" value="Na/H_antiporter_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004670">
        <property type="entry name" value="NhaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30341">
        <property type="entry name" value="PTHR30341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06965">
        <property type="entry name" value="Na_H_antiport_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00773">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0050">Antiport</keyword>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="8" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="401" mass="41726" checksum="B938DF6589BE17AB" modified="2010-04-20" version="1">MARKLVRKVAAVPAEVVRYLRVEATGGLILLVATAAALILANLSVTAEGYRRLTETTVGPEALHLNLTLGAWANDGLLAIFFLVAGLELKRELVSGELSSPRKAMLPLFAAVGGMAVPALVAFGVAFDAPGGGEVWPVPTATDIAFALAVLAVVASNLPSGVRVFLLSLAVVDDLGAITLIAVLYTDGIKLVPLAVSLACVAAYWLLQSRGIRFLPLYIVLGFIAWMTMHEAGVHATIAGVLLAFATRVKPRAGEKHAPALRLEHALQPLSAGVCVPVFAFFAAGISLEEDAMGAFLADRAALAVVAGLVIGKFIGVYGGSRLAVWLGAARLPSGLLWRDIAAVAFLTGCGFTVSLLMAELAFSDPAQQANVKAAVLIGSLLAALIAATVLRIRVKRRAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q939</accession>
    <name>D3Q939_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016219.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0937"/>
    <dbReference type="EnsemblBacteria" id="ADD40648">
        <property type="protein sequence ID" value="ADD40648"/>
        <property type="gene ID" value="Snas_0937"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0937"/>
    <dbReference type="eggNOG" id="COG4447">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054572_0_0_11"/>
    <dbReference type="OMA" id="ETWLIGS"/>
    <dbReference type="OrthoDB" id="1303819at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048772" evidence="1">
        <location>
            <begin position="37"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="376" mass="39893" checksum="963F6B6DCAB211D2" modified="2010-04-20" version="1">MKLSAKQRRRYLLLPIPAVAAVAIGAVFASSAMAEAAALEWTLTKTPDLGEKYSLSDVHAIAENDVWAVGETYHPDKAVALHWNGKEWEDSKAPEGSSLSDVSSVGEDVWAVGAADDKSTLTARWDGKAWEAVPSPQLELPDDSRPRLGSVHGVAADDVWAVGGSTGPMYPEGTTPILQHWDGTEWSFMDVPLPEGAVDAGLSAVRARAADDVWALGATFDAKEVMSPLLLHWNGKEWSTRDLPIAEALPQDIAFTEDGRIWLSGTVLPGSTPFDGKPLMVVGDGKTWNQLEVPAEKQSLPSITPDGTGGVVAVGGDGDKVMVVRSDGETVTREAAPAVEAEFSYLEGVSVVPGTETLWTVGFLDKFAAPVAAHTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q982</accession>
    <name>D3Q982_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xylose ABC transporter, substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2889</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2889"/>
    <dbReference type="EnsemblBacteria" id="ADD42564">
        <property type="protein sequence ID" value="ADD42564"/>
        <property type="gene ID" value="Snas_2889"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2889"/>
    <dbReference type="eggNOG" id="COG4213">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_13_1_11"/>
    <dbReference type="OMA" id="SARWIDD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048330" evidence="1">
        <location>
            <begin position="23"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="34"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="359" mass="38648" checksum="13128B4D9F1ED93C" modified="2010-04-20" version="1">MNLNRRSLLTSAAGLSTLAVLAACGGAGSEKGTVGIAMPTKSSERWIADGDNMVAAFKKAGFDTDLQYAEDVIETQVSQIENMITKGVKALVIAPVDNTSLTGALQQAADAGIKVISYDRLIRETDNVDYYATFDNFKVGELQGGYIEEKLKLADGEGPYNIELFAGSADDNNTAYFFDGAMSKLKPYIKSKKLVVRSGQTDMDDVTTLRWNGETAQSRMENILNANYGDERVDAVLSPYDGISLGIIAALQSDGYGEGDKPLPVVTGQDAEIASVKSILAGEQTQTVYKDTRKLAKLAVEMTSAAIDGKKAKTNDTESYDNGKKVVPAYLLKPVSVDKDNVEEALVETKQYTKKQLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9C2</accession>
    <name>D3Q9C2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome bd ubiquinol oxidase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Snas_2929</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018175.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2929"/>
    <dbReference type="EnsemblBacteria" id="ADD42604">
        <property type="protein sequence ID" value="ADD42604"/>
        <property type="gene ID" value="Snas_2929"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2929"/>
    <dbReference type="eggNOG" id="COG1271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030555_3_3_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="183"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="295"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD42604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="407" mass="45056" checksum="3F98D1A1138A2A42" modified="2010-04-20" version="1">MTAVDVARLQFAVTTSIHWMFVLVTLGLVVVLVTLQTRAALTRNPVKRALHFRMTRYWGLIYVINYSVGIASGIIMEFQFGTNWSGLSHLVGDVFGAPLAVETLVAFVAESTFLALWIFGWGKLPVWIHTLLIWLVAASAYASAFWVLVANGFMQNPTGFELTDDGRANLTSAAALFNNPSTIWAFVHILGAALTAGGVILVVVSAAHLFRRKEKDFFTRSFRLGYLMGLFGMIWAFGTGWAQYGFVNQIQPAKELGKGLGVEPAFHIMMLTAELATPIMLLLSPIVIWKLPAKLWFFMPLFWLALPFPFAAAIAGWVFREMGRQPWIVYGVQKTEDAVSDIGVTTLWTSFWLFTVLLGLLLLTNWWLITRHAVRGPNREIFGIEPDAGYGKPAAAPAPVLEGANRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9H5</accession>
    <name>D3Q9H5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein-export membrane protein SecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_2983</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Involved in protein export. Participates in an early event of protein translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SecG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2983"/>
    <dbReference type="EnsemblBacteria" id="ADD42657">
        <property type="protein sequence ID" value="ADD42657"/>
        <property type="gene ID" value="Snas_2983"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2983"/>
    <dbReference type="eggNOG" id="COG1314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094156_7_1_11"/>
    <dbReference type="OMA" id="WFACIVV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004692">
        <property type="entry name" value="SecG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03840">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01651">
        <property type="entry name" value="SECGEXPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00810">
        <property type="entry name" value="secG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD42657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="80" mass="8079" checksum="7658ED8C16BE258E" modified="2010-04-20" version="1">MYVLVGVLVVTSAALILLVLLHKGKGGGLSSMFGGGVSSNVSGSAVAEKNLDRITVIVGVLWLIGIVGFGILLRQIVSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAJ7</accession>
    <name>D3QAJ7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3109</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018351.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3109"/>
    <dbReference type="EnsemblBacteria" id="ADD42780">
        <property type="protein sequence ID" value="ADD42780"/>
        <property type="gene ID" value="Snas_3109"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3109"/>
    <dbReference type="eggNOG" id="COG1657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_966142_0_0_11"/>
    <dbReference type="OMA" id="MVCRINS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048371" evidence="3">
        <location>
            <begin position="36"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="288" mass="28068" checksum="296165653945C5D2" modified="2010-04-20" version="1">MTRMRFGLRHLAAILGLTVAALPPVVLADAPAAHAAVCSPGSGVSVIVDFGALGSVKSGCASGAPSTGLKALSGAGFSYSYVPGQTGMVCRINSLPDPCPSGGPPVDKYWSYWVAERGGTWKYSSKGAGNRTPPVGSVDGWAFGAGKPPATAPPAKGSSSGGGGDSDGGGDGSGDGGGSGGGGKDDGGSKKSGKPGDPSASDKKKDRDSPSASGSGSQTAPGAEDPAADPGSGSDGYDNASNVGSQMGTVGGIFGAGIVLVLLAALGWRTWQRRRGETEPVEAAEPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAQ5</accession>
    <name>D3QAQ5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Epoxide hydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5065</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020272.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5065"/>
    <dbReference type="EnsemblBacteria" id="ADD44701">
        <property type="protein sequence ID" value="ADD44701"/>
        <property type="gene ID" value="Snas_5065"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5065"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_1_11"/>
    <dbReference type="OMA" id="VGVHVNY"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033961">
        <property type="term" value="F:cis-stilbene-oxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EHN" evidence="3">
        <location>
            <begin position="5"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="362" mass="40163" checksum="5C5F15994DF708E6" modified="2010-04-20" version="1">MTTAITPFRVDIPQADLDDLADRLDRARWPQEPAESGSHYGIPRSRVTALAEYWRTDFDWRAVETALNAHPQFTTEIDGQNIHFIHVRAADPDALPLILTHGWPGSVIEFLDVIEPLSRDFQLVIPSIPGFGFSGPTSQPGWDVARVARAWAELMRRLGYERYGAQGGDWGSAISRVLGDLEPERVVGVHLNYLTMPPPPGGPGELSGEDTRRLDGVREYLANQPVQRTVHSIAPQLVGYGLNDSPIGLLAWLLDRFDAWADPASKLSPDKILADVSLYWLTGTAASAPRIHRDSPPGPLPCPVPLGVAVFAREITLPIRSFAEAVYDIRHWREYDHGGHFAAMEVPELFTADVREFFGSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAR5</accession>
    <name>D3QAR5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyoxalase_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020282.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5075"/>
    <dbReference type="EnsemblBacteria" id="ADD44711">
        <property type="protein sequence ID" value="ADD44711"/>
        <property type="gene ID" value="Snas_5075"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5075"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108054_0_0_11"/>
    <dbReference type="OMA" id="HWKLVID"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase_6" evidence="1">
        <location>
            <begin position="6"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="142" mass="16173" checksum="8B2080E77422C486" modified="2010-04-20" version="1">MAYGFQITIDSQTPHQLADWWAEALGWQVEPSDEEFIRRMVSEGHADEADTTTHNGVLVWKAGQAIRHPDDESYPRFLFQLVPEPKTVKNRMHLDVRVGADKIESELERLTATGATFLHRGNQGPFRWITITDPEGNELCLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAS8</accession>
    <name>D3QAS8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020295.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5088"/>
    <dbReference type="EnsemblBacteria" id="ADD44724">
        <property type="protein sequence ID" value="ADD44724"/>
        <property type="gene ID" value="Snas_5088"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5088"/>
    <dbReference type="eggNOG" id="COG3153">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102144_0_0_11"/>
    <dbReference type="OMA" id="HIEYQND"/>
    <dbReference type="OrthoDB" id="1405551at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="247" mass="26774" checksum="EA81083BE116DE5E" modified="2010-04-20" version="1">MTISRIIELGEPGPDFDAVYRDMLAPNFPAHELEPAEVIAEGIAAGTTSVLVALAEDGHRLGTAIGEWDADHRVQLLTYLAVDGRRRAGGVGGRLLDAARQRWVARYRPLVLLAEVEHPATEAGEAAWGDPRRRFDFYVRRGARVLDLPYFQPALGEGAQRGYGMLLITLYLDDEFREPGADRVPSAPVRGFLEDYLRECEGEVADDAATTALLAACADDRGIGLLDPAATPVERLPRSTPNAAGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAT6</accession>
    <name>D3QAT6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020303.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5097"/>
    <dbReference type="EnsemblBacteria" id="ADD44732">
        <property type="protein sequence ID" value="ADD44732"/>
        <property type="gene ID" value="Snas_5097"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5097"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052806_1_0_11"/>
    <dbReference type="OMA" id="FTDRRVE"/>
    <dbReference type="OrthoDB" id="1467120at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="303" mass="33642" checksum="B599F4563C1EFFDF" modified="2010-04-20" version="1">MSDRNALFTIGELARRTGLAVRTIRFWSDEGVVPETTRSATGYRLYDAEAVARLDLVKTLRELGLDLEKVREVLHRQATVADVAAAHARALDVEIRTLKVRRAVLRSVAHRNSSTEEMRIMHKMAKLSAAERQQLLDEFVEKTFEGVSPQAPGAKIAQGMRTLPAELPDDPSPEQVDAWVELAELVSDKDFQARVRQMAVAGDTDEPQAGPPYDPEQFAEATGIALAENVDPASARGRELLDRLFDAGLAGDERRKLADDLETFTDRRVERYWSLLGVLNGWPGRPSMVQAMEWVIAALRASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB75</accession>
    <name>D3QB75_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elongation factor G</fullName>
            <shortName evidence="6">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fusA</name>
        <name evidence="8" type="ordered locus">Snas_1182</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1182"/>
    <dbReference type="EnsemblBacteria" id="ADD40892">
        <property type="protein sequence ID" value="ADD40892"/>
        <property type="gene ID" value="Snas_1182"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1182"/>
    <dbReference type="eggNOG" id="COG0480">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002794_4_2_11"/>
    <dbReference type="OMA" id="AATTCHW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="9"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="18"/>
            <end position="25"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="82"/>
            <end position="86"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="699" mass="77100" checksum="68AE95C91008AC73" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBA4</accession>
    <name>D3QBA4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phospholipid N-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1211</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1211"/>
    <dbReference type="EnsemblBacteria" id="ADD40921">
        <property type="protein sequence ID" value="ADD40921"/>
        <property type="gene ID" value="Snas_1211"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1211"/>
    <dbReference type="eggNOG" id="COG3963">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085338_2_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="209" mass="22190" checksum="C64E199517042840" modified="2010-04-20" version="1">MTHEPGTPKPPSYLRDVGVFFRHWLKAPGKTGAVWPSSRFLARSLASALDGYSQPAVAELGPGTGPATAQIQARLAGAGTHVAVDLNPQFASMLAARFPDVDVVCDSADRLPAILAERDITVVDAVVSGLPFAAFPAGLQRDILDAVVASLHPGHGVFTTFNYVGAFSLPPARRFRGLLAERFEEISISGPVLRNIPPAYVLTARKPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBE2</accession>
    <name>D3QBE2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Carbamoyl-phosphate synthase large chain</fullName>
            <ecNumber evidence="15">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Carbamoyl-phosphate synthetase ammonia chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">carB</name>
        <name evidence="19" type="ordered locus">Snas_3153</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="15">Binds 4 Mg(2+) or Mn(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="15">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the CarB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="15"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018395.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3153"/>
    <dbReference type="EnsemblBacteria" id="ADD42824">
        <property type="protein sequence ID" value="ADD42824"/>
        <property type="gene ID" value="Snas_3153"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3153"/>
    <dbReference type="eggNOG" id="COG0458">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000513_1_0_11"/>
    <dbReference type="OMA" id="IEPAGIH"/>
    <dbReference type="OrthoDB" id="48855at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01424">
        <property type="entry name" value="MGS_CPS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_B">
        <property type="entry name" value="CPSase_L_chain_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CarbamoylP_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CbamoylP_synth_lsu_CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033937">
        <property type="entry name" value="MGS_CPS_CarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="SSF48108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 15" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="11 15 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 15 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 15" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="17">
        <location>
            <begin position="133"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="17">
        <location>
            <begin position="686"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="18">
        <location>
            <begin position="959"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carboxyphosphate synthetic domain" evidence="15">
        <location>
            <begin position="1"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric domain" evidence="15">
        <location>
            <begin position="959"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="836"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="848"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="850"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ADD42824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1105" mass="117395" checksum="E626BE9B5C5CE78F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBF3</accession>
    <name>D3QBF3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase C60 sortase A and B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3164</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3164"/>
    <dbReference type="EnsemblBacteria" id="ADD42835">
        <property type="protein sequence ID" value="ADD42835"/>
        <property type="gene ID" value="Snas_3164"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3164"/>
    <dbReference type="eggNOG" id="COG3764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062592_5_0_11"/>
    <dbReference type="OMA" id="GPAIFLN"/>
    <dbReference type="OrthoDB" id="1771853at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05829">
        <property type="entry name" value="Sortase_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042001">
        <property type="entry name" value="Sortase_F"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
        <property type="entry name" value="Sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048412" evidence="3">
        <location>
            <begin position="35"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="208" mass="21607" checksum="49C9AF97932E035A" modified="2010-04-20" version="1">MAVCLTLTVIAAAGCGLMLGALTPLPSTSPQPQAVPVPPSVPPVPSLSPGQIAPPGLSRSTPTVVDIAAIGVHSPVTPVGLDRDGTIEAPDLDQPHQTGWYSHGPAPGQIGTAALVGHVDSRRSGAAVFYDLGSLETGDSIVVSRRDGRDVTFTVDLVESYPKKKFPYGAVFTNTGYAALRLITCGGNFDTKRRSYTHNIVVYATMAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBP9</accession>
    <name>D3QBP9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3261</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3261"/>
    <dbReference type="EnsemblBacteria" id="ADD42931">
        <property type="protein sequence ID" value="ADD42931"/>
        <property type="gene ID" value="Snas_3261"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3261"/>
    <dbReference type="eggNOG" id="COG3119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_11_0_11"/>
    <dbReference type="OMA" id="EAYPMVQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="48"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="19"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="785" mass="86007" checksum="4F47704A69B5EE0A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBV9</accession>
    <name>D3QBV9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nitrate reductase (quinone)</fullName>
            <ecNumber evidence="7">1.7.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Snas_5213</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinol + nitrate = a quinone + H2O + nitrite</text>
            <dbReference type="Rhea" id="RHEA:56144"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.7.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.7.5.1" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5213"/>
    <dbReference type="EnsemblBacteria" id="ADD44848">
        <property type="protein sequence ID" value="ADD44848"/>
        <property type="gene ID" value="Snas_5213"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5213"/>
    <dbReference type="eggNOG" id="COG5013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_14_1_11"/>
    <dbReference type="OMA" id="GGHHNSV"/>
    <dbReference type="OrthoDB" id="88184at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009325">
        <property type="term" value="C:nitrate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008940">
        <property type="term" value="F:nitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042126">
        <property type="term" value="P:nitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02776">
        <property type="entry name" value="MopB_CT_Nitrate-R-NarG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037943">
        <property type="entry name" value="MopB_CT_Nitrate-R-NarG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027467">
        <property type="entry name" value="MopterinOxRdtase_cofactor_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006468">
        <property type="entry name" value="NarG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01580">
        <property type="entry name" value="narG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00551">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00490">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="13">
        <location>
            <begin position="49"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD44848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1216" mass="134370" checksum="299E1E12451DC7D8" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBW7</accession>
    <name>D3QBW7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutaredoxin/malate transporter fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020427.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5222"/>
    <dbReference type="EnsemblBacteria" id="ADD44856">
        <property type="protein sequence ID" value="ADD44856"/>
        <property type="gene ID" value="Snas_5222"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5222"/>
    <dbReference type="eggNOG" id="ENOG5032J0V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115719_0_0_11"/>
    <dbReference type="OMA" id="AFPNPVN"/>
    <dbReference type="OrthoDB" id="1006128at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025508">
        <property type="entry name" value="DUF4395"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14340">
        <property type="entry name" value="DUF4395"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4395" evidence="2">
        <location>
            <begin position="20"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="172" mass="18118" checksum="C1E90386EAEBB0FF" modified="2010-04-20" version="1">MNASRSDTVVGRLFAFPNPVNEISARLVAGGVVLMCVAAIAFDQPWLTAVIAYGFVARVLTGPTLSPLGQLVTRFITPRLPVEPVWVAGPPKRFAQGIGVVFSVTAAVLALGLGLHTAAWIVLGALAVAATLESVFAFCLGCKMFAVLMKTGLIPEQVCLECSDLSLRYGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTZ8</accession>
    <name>D3PTZ8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015327.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0034"/>
    <dbReference type="EnsemblBacteria" id="ADD39756">
        <property type="protein sequence ID" value="ADD39756"/>
        <property type="gene ID" value="Snas_0034"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0034"/>
    <dbReference type="HOGENOM" id="CLU_1926278_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="131" mass="14233" checksum="E79F3A56C9DE80B0" modified="2010-04-20" version="1">MTSEIRLDKRALREFISLMDQTAEEMADIQDGTTPRYARSGGGGEAAYRNGVKVTVGSVDFAHPGRVAGELMADRIAETLEFVRSLEEGSRALARIVRSVLDDMGARDSIAASDLARINNSMEGRSRGDQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU58</accession>
    <name>D3PU58_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfate adenylyltransferase subunit 2</fullName>
            <ecNumber evidence="2">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">ATP-sulfurylase small subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sulfate adenylate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1295</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PAPS reductase family. CysD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016575.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1295"/>
    <dbReference type="EnsemblBacteria" id="ADD41004">
        <property type="protein sequence ID" value="ADD41004"/>
        <property type="gene ID" value="Snas_1295"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1295"/>
    <dbReference type="eggNOG" id="COG0175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043026_0_0_11"/>
    <dbReference type="OMA" id="LMIDTGH"/>
    <dbReference type="OrthoDB" id="499077at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019419">
        <property type="term" value="P:sulfate reduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011784">
        <property type="entry name" value="SO4_adenylTrfase_ssu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002936">
        <property type="entry name" value="CysDAde_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02039">
        <property type="entry name" value="CysD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="7">
        <location>
            <begin position="32"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="302" mass="34255" checksum="564C4693B3EEA205" modified="2010-04-20" version="1">MSDCDYRVSHLDALEAESIYIFREVVATCERPVLLFSGGKDSVVMLHLAAKAFAPAPIPFPVMHVDTGHNFAEVLEYRDNRVRDLEIELLVASVPDAIAAGKVVEPPDGMRNRIQTPVLLDAVEKYRFNALFGGARRDEEKARAKERVFSFRDEFGQWDPKNQRPELWSLYNGRTHPGESIRVFPLSNWTELDIWHYIDEQDIPLPSIYYAHDREVVERDGMLYAVNEFIQPKETETTVVKRVRYRTVGDASCTAAVESDAANAADVIAEVAATRITERGATRGDDRVSEAAMEDRKREGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU59</accession>
    <name>D3PU59_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sulfate adenylyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1296</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.4" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016576.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1296"/>
    <dbReference type="EnsemblBacteria" id="ADD41005">
        <property type="protein sequence ID" value="ADD41005"/>
        <property type="gene ID" value="Snas_1296"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1296"/>
    <dbReference type="eggNOG" id="COG2895">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_5_2_11"/>
    <dbReference type="OMA" id="FPVQYVL"/>
    <dbReference type="OrthoDB" id="244339at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04166">
        <property type="entry name" value="CysN_ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03695">
        <property type="entry name" value="CysN_NodQ_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04095">
        <property type="entry name" value="CysN_NoDQ_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041757">
        <property type="entry name" value="CysN_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044138">
        <property type="entry name" value="CysN_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044139">
        <property type="entry name" value="CysN_NoDQ_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011779">
        <property type="entry name" value="SO4_adenylTrfase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02034">
        <property type="entry name" value="CysN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="5"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="421" mass="46436" checksum="2C358F70D96D7EB8" modified="2010-04-20" version="1">MNETTEMLRFATAGSVDDGKSTLIGRLLYDTKTIFEDQLEAVESVSKARGDDYTDLALLTDGLRSEREQGITIDVAYRYFATPRRKFIIADTPGHTQYTRNMVTGASTADLALILVDARKGLVEQSRRHAFLCSLLRVPHLVLCVNKMDLVDYSQEVFEKIASEFTAFATKLDIPDLTIIPVSALAGDNVVSRSDKMPWFEGTSLLHHLESVHIASDRNLVDARFPVQHVIRPHSNSNHDYRGYAGQVASGVLKPGDEVMVLPSGFTTTIAGIDTADGPVEQAFPPMSVTVRLADELDVSRGDLICRPNNAPRVAQDVEAMICWMDEKQPLQPGRKYAIAHTTRAARGLVKDLHYRLDVNTLHRDESADGLTLNEIGRVTLRTTVPLLCDPYRRNRATGGFIVIDEGTNRTVGAGMIVEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU75</accession>
    <name>D3PU75_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit b</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP synthase F(0) sector subunit b</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">ATPase subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit b</fullName>
            <shortName evidence="13">F-ATPase subunit b</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">atpF</name>
        <name evidence="16" type="ordered locus">Snas_1312</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).</text>
    </comment>
    <comment type="function">
        <text evidence="11 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12 13">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cell membrane</location>
            <topology evidence="1 13">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13 14">Belongs to the ATPase B chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016592.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1312"/>
    <dbReference type="EnsemblBacteria" id="ADD41021">
        <property type="protein sequence ID" value="ADD41021"/>
        <property type="gene ID" value="Snas_1312"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1312"/>
    <dbReference type="eggNOG" id="COG0711">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079215_5_1_11"/>
    <dbReference type="OMA" id="FAWKPIL"/>
    <dbReference type="OrthoDB" id="1999641at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01398">
        <property type="entry name" value="ATP_synth_b_bprime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028987">
        <property type="entry name" value="ATP_synth_B-like_membr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002146">
        <property type="entry name" value="ATP_synth_b/b'su_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005864">
        <property type="entry name" value="ATP_synth_F0_bsu_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00430">
        <property type="entry name" value="ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81573">
        <property type="entry name" value="SSF81573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01144">
        <property type="entry name" value="ATP_synt_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 13 14" id="KW-0138">CF(0)</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 13 14" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 13 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="60"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ADD41021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="181" mass="19856" checksum="19FE36EC3483F4E3" modified="2010-04-20" version="1">MKTATQILAESDHNPIVPIWQELVVGTVAFAILCFVLMKFVFPKMEQTFRARVDAIEGGIKRAEETQAKANELLEQYKQQLAEARTEAASIRDEARAEAIAAKEEIVTEARTEAERIINAGKESLAASRQQLLTELRGEVGEIAVELAGRIVGESLADEARRSGTVERFLSELDADSAGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU98</accession>
    <name>D3PU98_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016615.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1335"/>
    <dbReference type="EnsemblBacteria" id="ADD41044">
        <property type="protein sequence ID" value="ADD41044"/>
        <property type="gene ID" value="Snas_1335"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1335"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_15_7_11"/>
    <dbReference type="OMA" id="QRCFRTK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="194" mass="20819" checksum="7A12B67E17017AE7" modified="2010-04-20" version="1">MTGEEDVRGAHLLDAVLSVIAEDGFAAVSMRTVAARAGVSLAQVQYYFKSKDDLIRAGFDHAGRLFLATLSAIRAEEPSVERLRAIVTLWLPLDAAREKRARVWLAYSAAAAVSPELAAEAAGLDAELRDWFAAELRGLVMTGTVRATVDPAATAARLLALIDGVTVQALMLPDDQREPLTRTVIDSFLAELGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUA5</accession>
    <name>D3PUA5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016622.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1343"/>
    <dbReference type="EnsemblBacteria" id="ADD41051">
        <property type="protein sequence ID" value="ADD41051"/>
        <property type="gene ID" value="Snas_1343"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1343"/>
    <dbReference type="HOGENOM" id="CLU_2686053_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="74" mass="8103" checksum="38F78F3E89C39036" modified="2010-04-20" version="1">MDEYDDSLDDTSHDAELEDDSAAYSEDVSYDESSWGDEDEGSSFDPPETPPTRPSWVAASSDAHRCRGTTPVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUH1</accession>
    <name>D3PUH1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018555.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3318"/>
    <dbReference type="EnsemblBacteria" id="ADD42984">
        <property type="protein sequence ID" value="ADD42984"/>
        <property type="gene ID" value="Snas_3318"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3318"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="LMTRWAE"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="36202" checksum="9870233F5822A6FD" modified="2010-04-20" version="1">MEYTKLGRCGLSVSRLCLGTMNFGPHTSVEDSHAIMDRALETGFNYFDTSNSYGGRRGEGVTEQIIGQWFDQRESARDKVVLATKVYTPMSQWPNEGRLSARHIIASCEASLRRLRTDWIDVFQMHHVDRDVTWDEIWQAMETLVAQGKIRYAGSSNFAGWHLAAAQEAANRRHFLGLVSEQCRYNLITRHPELDVIPAATHYGIGIVPWSPLESGLLAGVLAKQAARTSVRGDNDRAELMRQHRDSIDGYEKLCADIGTDPAALGIAWLLSRPGVTAPIIGPRTTEQLDSALSALDVTVDAEVEVRLDELFPPIGSGGPSPEAWAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUL9</accession>
    <name>D3PUL9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucose sorbosone dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018603.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43032">
        <property type="protein sequence ID" value="ADD43032"/>
        <property type="gene ID" value="Snas_3368"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3368"/>
    <dbReference type="eggNOG" id="COG2133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012253_0_0_11"/>
    <dbReference type="OMA" id="RLWRIPL"/>
    <dbReference type="OrthoDB" id="567019at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049470" evidence="1">
        <location>
            <begin position="34"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="GSDH" evidence="2">
        <location>
            <begin position="48"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="353" mass="37500" checksum="4C7E32554F29712A" modified="2010-04-20" version="1">MTTKRRTGTLLGAILAIAALTACAPAPSSNKGAKPSDTGDPDVVADNLEAPWSIAFHGSTPLVSERDSAKILELDKDGDPREVATIDGVAGEGEGGLLGLAVKDDDLFVYSTGAGENRVERYPIKGEAGALELGEPKELLDGIAAASYHNGGRIAFGPDKMLYVTTGDAGEPETAQDRKSLSGKILRMTPDGEVPSDNPDSDSLVYSFGHRNPQGMAWSEDGTMYATEFGQDTWDELNVIEPGGNYGWPEVEGIAEDEDFTDPVQQWEPAEASPSGMAITGDTALIANLRGERLFEVPLDKPSTSAEHFVAEFGRLRDVVVAPDGSLWMLTNNTDGRGDPGADDDRILSFEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUP3</accession>
    <name>D3PUP3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phytanoyl-CoA dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3392</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018627.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3392"/>
    <dbReference type="EnsemblBacteria" id="ADD43056">
        <property type="protein sequence ID" value="ADD43056"/>
        <property type="gene ID" value="Snas_3392"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3392"/>
    <dbReference type="eggNOG" id="COG5285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048953_9_0_11"/>
    <dbReference type="OMA" id="CIVKNVI"/>
    <dbReference type="OrthoDB" id="1070946at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="29088" checksum="19F5F95CBE81116A" modified="2010-04-20" version="1">MVDQATVLEQYHRDGYAIFRDVLDAELVAEASDHVEWLQRKHPDVRPEQLGHQYLRDDPFWIRLVSDDRLVDIAELFVGPDIALFASHYISKPPFSGQPVLWHQDAAFWPLEPMEVVTLWLAVDHSTPENGCVRLIPGSHTTPTAATRDAAEVDNVLGAEIAVEVDEARAVDMVLAPGDVEVHHPNIVHGSNANTSAKRRCGLTIRYIPTSTRITGDEQPFPSALWLRGDRGVNTYQPVPDFDAGRHFRYRGAGEGSSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUQ4</accession>
    <name>D3PUQ4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020499.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5294"/>
    <dbReference type="EnsemblBacteria" id="ADD44928">
        <property type="protein sequence ID" value="ADD44928"/>
        <property type="gene ID" value="Snas_5294"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5294"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085376_2_0_11"/>
    <dbReference type="OMA" id="TGMTKSY"/>
    <dbReference type="OrthoDB" id="1292067at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="18"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="194" mass="21492" checksum="5C081359738F8FCE" modified="2010-04-20" version="1">MVGVEELDEVLTAVGPRLRELRRQRNVTLARLAEATGISESTLSRLESGARRPNLELLLPLAKVYGVPLDELVGAPTTGDPRVHLRPVHRGGMTFIPLTRRAGGIQSYKMVIPGDTSGREPDLKTHEGYEWMYVLNGRLRLLLGDKDLVLNPGEVAEFDTHVPHWLGAAEDAPVELLILFGQQGERAHLRARSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUW7</accession>
    <name>D3PUW7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5358</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5358"/>
    <dbReference type="EnsemblBacteria" id="ADD44991">
        <property type="protein sequence ID" value="ADD44991"/>
        <property type="gene ID" value="Snas_5358"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5358"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_34_4_11"/>
    <dbReference type="OMA" id="RIRAHQF"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="9"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="166" mass="18345" checksum="85A04368B5725661" modified="2010-04-20" version="1">MIEPRMKPPELRLAHTTDAAAVNDLLHQLGYPQDDTATTAARIQTWNDDPASAAYVADANGVLLGLVAVHVCPYFERNGSWGRIVALVVADQARGQGLGGKLVAAAESFAESQGCVRMEVSSSNRREAAHKFYRHRGYINQTDRSSRFQRDLHDTNHREDHPLPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV41</accession>
    <name>D3PV41_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1387</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016665.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1387"/>
    <dbReference type="EnsemblBacteria" id="ADD41094">
        <property type="protein sequence ID" value="ADD41094"/>
        <property type="gene ID" value="Snas_1387"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1387"/>
    <dbReference type="eggNOG" id="ENOG5031VPJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1293546_0_0_11"/>
    <dbReference type="OMA" id="WATMETS"/>
    <dbReference type="OrthoDB" id="2037900at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="205" mass="22370" checksum="AA201E3ACFC179C4" modified="2010-04-20" version="1">MSMTILPVGKPLGACFPPADPPAEQPDFYEVHVANDVEQLTELEWQVYYAAYGEPDQHAEHRVDRDWVIKSLSNDLSTSKVSATVDDLVGRGLLVEANLHGNSAMDVLTGYRLIPTAVGISNAPEDPNLRWIGQHGEGMLGIPQLSFLIWSFSYRTASMWDCCAMFAENPDSVDGATAQDIGAQIADSLPSIVSMELGYLEPSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV48</accession>
    <name>D3PV48_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase PA-phosphatase related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016672.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1394"/>
    <dbReference type="EnsemblBacteria" id="ADD41101">
        <property type="protein sequence ID" value="ADD41101"/>
        <property type="gene ID" value="Snas_1394"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1394"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1276971_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="123"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="216" mass="22433" checksum="61F8C757742454EF" modified="2010-04-20" version="1">MTTEPKTHHRRLAATGLAAVTTSILIGLLLRDVVPPADAWIIDHWYAAPDSLITTIATATSGVGTLLALAAVPAAAITLLIRRRAQGKPHLSLLARGLLLIPICGSVLAIQQLVMRPGPPMQPEASTYPSGHATIATAALFTAAVLFWLADPRWGRLAASTGAVAVLAVSASRVVLAEHWLLDVAGAITATAGIGLLAIAVLRIVPWWQPATAPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVF9</accession>
    <name>D3PVF9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, ArgP, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018644.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3409"/>
    <dbReference type="EnsemblBacteria" id="ADD43073">
        <property type="protein sequence ID" value="ADD43073"/>
        <property type="gene ID" value="Snas_3409"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3409"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063829_0_1_11"/>
    <dbReference type="OMA" id="QQWKLDS"/>
    <dbReference type="OrthoDB" id="951478at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017685">
        <property type="entry name" value="ArgP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03298">
        <property type="entry name" value="argP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="299" mass="32626" checksum="C311DCD571F317EB" modified="2010-04-20" version="1">MMELPFDQVRTLLAVVDEGTFEAAAAALHVTPSAVSQRVKTLEQRTGRVLLMRTKPVRPTESGQVVVRFARQLAAMENDARLALGLASASAPARLPIAVNADSLATWFQQALTRVPQDPPIYFELYREDESHTATLLREGRVMAAVTSSAEPVAGCTVRVLGRARYLPVANPEFAKRHLSSGVLERCLPDAPVIVFDRRDDLQDRFLRDFTPDGRGASQLRHQIPTSEGFCEAVAAGLGWGLVPEPQAEPLLKTGSLVELIPGQPVDVPLYWQQWKLDVPALTLVAETIAVSATEALYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVH3</accession>
    <name>D3PVH3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018658.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3423"/>
    <dbReference type="EnsemblBacteria" id="ADD43087">
        <property type="protein sequence ID" value="ADD43087"/>
        <property type="gene ID" value="Snas_3423"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3423"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052868_1_0_11"/>
    <dbReference type="OrthoDB" id="1518440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026669">
        <property type="entry name" value="Arsenite_MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43675">
        <property type="entry name" value="PTHR43675"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="70"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="241" mass="24706" checksum="388D4D12BB3FD5E5" modified="2010-04-20" version="1">MSHKNIVDKYSSLARSALDGATVSDCEPRAFADGKFGAGGYVTLDDLPEGAARASLGCGDPVAVANLRPGDVVLDLGSGGGIDVLLSARRVLPGGSAYGLDASADMVALARRYAAEAGVDNVEFLQGDIENIPLPDGSVDVVISNCVLCLSSDKSATLTEAFRVLKPLGRFGISDVVAAGEADPLERERIEERIGCSAGTLTTIEYRDMLSAIGFADVAITLTADHGAGVHSAIVQAAKPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVZ9</accession>
    <name>D3PVZ9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5489"/>
    <dbReference type="EnsemblBacteria" id="ADD45120">
        <property type="protein sequence ID" value="ADD45120"/>
        <property type="gene ID" value="Snas_5489"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5489"/>
    <dbReference type="HOGENOM" id="CLU_3048228_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="54" mass="5514" checksum="3FF34A75DE855FCC" modified="2010-04-20" version="1">MTHHSGAAVASAPARFHDAPRFAAPALTPVGERARSQQCDVEAAASVRTTGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW19</accession>
    <name>D3PW19_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5509</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020711.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5509"/>
    <dbReference type="EnsemblBacteria" id="ADD45140">
        <property type="protein sequence ID" value="ADD45140"/>
        <property type="gene ID" value="Snas_5509"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5509"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="GSMPRID"/>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="9"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="347" mass="37859" checksum="97A64C6BED88504C" modified="2010-04-20" version="1">MSNDTNPYLSIEDLKVHFKTEDGIVKAVDGVSYTVSEGETLGVVGESGSGKSVTGMALLGLHDPKRANISGKIFVDGTDILSLNEEKQRRMRGQKVSMIFQDALTALHPYYSIGKQIVEAYRLHHDVSKATAKKRAIEMLDRVGIPQPDKRFSQYPHEFSGGMRQRAMIAMSLVNNPRLIIADEPTTALDVTVQGQILDLLADLQKEFNSAIIMITHDLGVISDIADRIVVMYGGKVVETGTALNVMAQPQHPYTWGLLNSVPTLKGDAGEDLKPIPGNPPSLLNVPSGCAFHPRCVYALGPQTACEVEVPKLLGISGEPEHESACHLPEATRRRIMESEVRKVEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW37</accession>
    <name>D3PW37_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_5527</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5527"/>
    <dbReference type="EnsemblBacteria" id="ADD45158">
        <property type="protein sequence ID" value="ADD45158"/>
        <property type="gene ID" value="Snas_5527"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5527"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_11"/>
    <dbReference type="OMA" id="RYFEVMD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="45"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="363"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="397"/>
            <end position="404"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD45158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="604" mass="64772" checksum="5338669132448B7B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW74</accession>
    <name>D3PW74_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1527"/>
    <dbReference type="EnsemblBacteria" id="ADD41231">
        <property type="protein sequence ID" value="ADD41231"/>
        <property type="gene ID" value="Snas_1527"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1527"/>
    <dbReference type="HOGENOM" id="CLU_1229266_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="225" mass="22865" checksum="E42BBC5CD00CC77A" modified="2010-04-20" version="1">MPRARHDGEIAVAAGRQEPVLVAAQVIALTVDQPHPTRVTGQCGEHVESDQRVEDLGDDVGEQPALAGHVGGLAAEHQSQCLPLPPLPALAADTGQCPVRPDQPGRRHGGAPDRHQPGDPLGMAGGRGDADVPAQRYPRDQRPGVGVDGLGDGVGGGLDAEALPGTGSVAGQIDRDHRTCGGQVLGVGTPHAAAQPDAVDEDDGGGAHDCSFGSKNNATVRCVLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWE3</accession>
    <name>D3PWE3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1597</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016871.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1597"/>
    <dbReference type="EnsemblBacteria" id="ADD41300">
        <property type="protein sequence ID" value="ADD41300"/>
        <property type="gene ID" value="Snas_1597"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1597"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_683172_0_0_11"/>
    <dbReference type="OMA" id="WFATGHA"/>
    <dbReference type="OrthoDB" id="1756441at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="403" mass="42786" checksum="C5349B4F88A52850" modified="2010-04-20" version="1">MTATTTNPTRYRALTWAPVAVLAWTLTYGAIRVYWAAGHMPTFAPMPEDLVIFPGWGAVGLCVAAGLAAVGLRLSSRSRLVLAGAWATVAAIVVASPMFLLDVVGGILAGLGIPVSLVSVASRGGMLLGAGLLAVAAVAYQRRLRGACSRCGRLGRASDGPADARERSAPAWAVWAAYVAVAGCLVRIAAQLAWGFEGFLYDGGAALLVFEVGFVLAGVLLPTALVHRFGLVWPRWVLPLAGRRVPRWLVLGPAFFVGLGLTVYFGMGLAQLVVDTVSGAAFVDDGSGYGAGFMWIAVPSYFVWGVGVGVAALARFRQTRPRCRHCGQLHRAPVNPHLTRKNCRECDKSGAIGVARRTLFGPGFGKNENRVQYKCRGTQGRHHRRDAAGEGRSGRHHRRHGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWW7</accession>
    <name>D3PWW7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase M28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5560</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020762.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5560"/>
    <dbReference type="MEROPS" id="M28.003"/>
    <dbReference type="EnsemblBacteria" id="ADD45191">
        <property type="protein sequence ID" value="ADD45191"/>
        <property type="gene ID" value="Snas_5560"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5560"/>
    <dbReference type="eggNOG" id="COG2234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4935">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024336_2_0_11"/>
    <dbReference type="OrthoDB" id="1465483at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048657" evidence="3">
        <location>
            <begin position="33"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="4">
        <location>
            <begin position="320"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="437" mass="45995" checksum="60DA45F82AEC00B2" modified="2010-04-20" version="1">MPRHRSRFAIALGAMAAAAMALSILSPTPASAEPADEATTAAAPDINVEDVKTHLSQFQSIASSNGGTRVAGSAGYDRSVDYVATALSNAGFQVTRQTCTSCNGSDQNVIADWPGGNTSTTIMFGAHLDSVSAGPGINDNASGSAALLEVALTLAEVKPTVAKHLRFAWWADEESGLRGSNYYVRTSGVSGIQAYVNLDMVGSTNAGYFVDNINGTYSAPFKNYFSSVGRAADEMGECCSDDGPFRNAGVPTSFLSTGASARKTTTQAQKWGGTAGQSFDPCYHQRCDSYPSNINVTAINHMADATAYGLWELAVDDDTQPPEGCANTNDADVAITDLATVTSSLGIAECGRQGGTASTVEVHIDHTWRGDLVLRLLAPDGTSYLLEDFNNNDQTDNVDKTYTVNLSGEAADGSWRLSVQDIARNDVGKIDTWTLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWZ6</accession>
    <name>D3PWZ6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020791.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5590"/>
    <dbReference type="EnsemblBacteria" id="ADD45220">
        <property type="protein sequence ID" value="ADD45220"/>
        <property type="gene ID" value="Snas_5590"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5590"/>
    <dbReference type="eggNOG" id="ENOG50324T6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112893_1_0_11"/>
    <dbReference type="OMA" id="HNGVRQV"/>
    <dbReference type="OrthoDB" id="1647035at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027580">
        <property type="entry name" value="EXLDI"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04342">
        <property type="entry name" value="EXLDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="173" mass="19555" checksum="783C11568C9A2CA6" modified="2010-04-20" version="1">MPNKTIYVSDDDLPLFQRAQELAGGKLSTAITAALRRYVEIAEGRMEGFEEVTVRVGAGVGRKVRFSGILLAEWGHSTSSRVDDYRVYRTRTGKYAVHIERSDEHYWSGQDAANWVEWVRAQFKTEQTWGYKAGEGVLEIAEDLEDLRDKIPAELHDIVASAVEQPPIEDLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXQ7</accession>
    <name>D3PXQ7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018958.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3730"/>
    <dbReference type="EnsemblBacteria" id="ADD43387">
        <property type="protein sequence ID" value="ADD43387"/>
        <property type="gene ID" value="Snas_3730"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3730"/>
    <dbReference type="HOGENOM" id="CLU_1255330_0_0_11"/>
    <dbReference type="OrthoDB" id="2006941at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="220" mass="22932" checksum="F57FA1281523FC3F" modified="2010-04-20" version="1">MNWADDSDSPTGDEAYPEPDPGMDDAAYDESTGDDEVSDFDAEDDTLDPDAEVSEDGDEPVASDEGAEGDADAEAADEGEQPAPDGPDADADVEDEPEPAGGDEPETDPDAEAIEITDDEVVGTDPDADLAADDPAFDAEFPPDIDMDARPEPVDGEPWSDASLLGSTSDAGTDWAAYDYSAPPMDDLFAMDGASSGSWDSLAASDDPAVSSLARWWQPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY16</accession>
    <name>D3PY16_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alkaline phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5715</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020916.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5715"/>
    <dbReference type="EnsemblBacteria" id="ADD45345">
        <property type="protein sequence ID" value="ADD45345"/>
        <property type="gene ID" value="Snas_5715"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5715"/>
    <dbReference type="eggNOG" id="COG3540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_525464_0_0_11"/>
    <dbReference type="OMA" id="DHEVRNN"/>
    <dbReference type="OrthoDB" id="165142at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032093">
        <property type="entry name" value="PhoD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16655">
        <property type="entry name" value="PhoD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049348" evidence="1">
        <location>
            <begin position="23"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD_N" evidence="3">
        <location>
            <begin position="46"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD" evidence="2">
        <location>
            <begin position="149"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="514" mass="56453" checksum="FA0D1AC6E552A2B6" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYT2</accession>
    <name>D3PYT2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3859"/>
    <dbReference type="EnsemblBacteria" id="ADD43515">
        <property type="protein sequence ID" value="ADD43515"/>
        <property type="gene ID" value="Snas_3859"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3859"/>
    <dbReference type="eggNOG" id="ENOG5032ZDA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2669287_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045745">
        <property type="entry name" value="HTH_58_Actinobacteria-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19575">
        <property type="entry name" value="HTH_58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_58" evidence="1">
        <location>
            <begin position="13"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="75" mass="8200" checksum="BB4D816CC1069237" modified="2010-04-20" version="1">MGHNDTRIGDGRSRRINGEERLALIKKLVAGYSEGHSIRSLAASVDRSYGFVHRVLSEAGVKLRKRGGRRGPAVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYT4</accession>
    <name>D3PYT4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019088.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3861"/>
    <dbReference type="EnsemblBacteria" id="ADD43517">
        <property type="protein sequence ID" value="ADD43517"/>
        <property type="gene ID" value="Snas_3861"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3861"/>
    <dbReference type="eggNOG" id="ENOG503303N">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_186986_0_0_11"/>
    <dbReference type="OMA" id="GHPTAFY"/>
    <dbReference type="OrthoDB" id="2076037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="67" mass="7343" checksum="79337D9D1084606A" modified="2010-04-20" version="1">MKFSRRIAGFVLAVAAFMVFEWVMLGFNLQPGHPTAFYVVHGVLIGVNLLIAVALAVVGVRAWRSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYV0</accession>
    <name>D3PYV0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="10">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="10">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">alaS</name>
        <name evidence="13" type="ordered locus">Snas_3878</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019104.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3878"/>
    <dbReference type="EnsemblBacteria" id="ADD43533">
        <property type="protein sequence ID" value="ADD43533"/>
        <property type="gene ID" value="Snas_3878"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3878"/>
    <dbReference type="eggNOG" id="COG0013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004485_1_1_11"/>
    <dbReference type="OMA" id="DTEACCG"/>
    <dbReference type="OrthoDB" id="91428at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="12">
        <location>
            <begin position="1"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="734"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="572"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="576"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="675"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="679"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD43533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="885" mass="95810" checksum="D044A4DC646F43ED" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ23</accession>
    <name>D3PZ23_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ppx/GppA phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021023.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5822"/>
    <dbReference type="EnsemblBacteria" id="ADD45452">
        <property type="protein sequence ID" value="ADD45452"/>
        <property type="gene ID" value="Snas_5822"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5822"/>
    <dbReference type="eggNOG" id="COG0248">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025908_1_2_11"/>
    <dbReference type="OMA" id="IGCVRMT"/>
    <dbReference type="OrthoDB" id="1862004at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx-GppA" evidence="1">
        <location>
            <begin position="38"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="321" mass="33770" checksum="9347ED5BEA1E9492" modified="2010-04-20" version="1">MNADKVSRELDYRSAPTTVAAIDCGTNSIRLLISRQSSDAAKPTDLVRIMRIVRLGEGVDTTGRISPAALDRTAAALREYAALIAEHQPSAVRMVATSASRDADNAAEFRDLVHGILGVMPEVITGDEEARLSFTGAVADLPPAAEPRLVVDIGGGSTEFVLGTDQAGPARSMDIGCVRMTERHLRGDPPSAEQVAAAEADITARVDEALATVDPNRTATELIGLAGSVTTVAALALGLDTYQPERIHHAEISYDDVRKVTMALLGQTREERLAHGVMHPGRADVIGGGALVLRIIMERCGATSVIASEHDILDGIAASLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ39</accession>
    <name>D3PZ39_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heavy metal transport/detoxification protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5838"/>
    <dbReference type="EnsemblBacteria" id="ADD45468">
        <property type="protein sequence ID" value="ADD45468"/>
        <property type="gene ID" value="Snas_5838"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5838"/>
    <dbReference type="eggNOG" id="COG2608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134973_13_1_11"/>
    <dbReference type="OMA" id="QTDTQGS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000428">
        <property type="entry name" value="Cu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00944">
        <property type="entry name" value="CUEXPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="69" mass="6993" checksum="59DBE575F37401F2" modified="2010-04-20" version="1">MTTGYAVTGMTCGHCATSVTNELNRVPGVETVSVDVEGGTVTIGSTTALDDEAVRAAVDEAGYQLTGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ55</accession>
    <name>D3PZ55_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45484">
        <property type="protein sequence ID" value="ADD45484"/>
        <property type="gene ID" value="Snas_5855"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5855"/>
    <dbReference type="HOGENOM" id="CLU_150710_2_0_11"/>
    <dbReference type="OrthoDB" id="2010577at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="65" mass="7132" checksum="59BB0F8F81BE6DFC" modified="2010-04-20" version="1">MTPLAIGGTVLWLVIAGILSLFSEDLAATGRSWWIDCALWGAVLGVPGTVVMVLHDRNQKRRQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ79</accession>
    <name>D3PZ79_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NLP/P60 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5880</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021079.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5880"/>
    <dbReference type="MEROPS" id="C40.007"/>
    <dbReference type="EnsemblBacteria" id="ADD45508">
        <property type="protein sequence ID" value="ADD45508"/>
        <property type="gene ID" value="Snas_5880"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5880"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034085_1_0_11"/>
    <dbReference type="OMA" id="VFFYDDV"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048487" evidence="4">
        <location>
            <begin position="28"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="5">
        <location>
            <begin position="201"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="32"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="315" mass="34044" checksum="377158704D359D0F" modified="2010-04-20" version="1">MKKRYAVIAAVAAAVLCVVITPATASAEPDTLEEVEDELDKKGNEMEKLAEKYNGAREDLKKTEKKIKKIKKQLPKYEKEAEESRKILSDIAYEEYTGGSQLVVAGSALAENPQEAMKRISVLGAINASQGAEISANSSTLKDLLEKKQDLEDLKDEQKKTKSDLKKKKKKLDGQIGELKELREKLGGGGDTGGSGPPPPSGRAGEVVQYAYDQLGDPYGYGQAGPDSFDCSGLTLAAWQQAGVSLYHKASVQREETASVSRSDLAPGDLVFYYSDLHHVALYVGDGKVVHAPQSGDVVKVANMNDMPVHSYGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZF9</accession>
    <name>D3PZF9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH-dependent FMN reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017204.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1937"/>
    <dbReference type="EnsemblBacteria" id="ADD41633">
        <property type="protein sequence ID" value="ADD41633"/>
        <property type="gene ID" value="Snas_1937"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1937"/>
    <dbReference type="eggNOG" id="COG0431">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055322_2_2_11"/>
    <dbReference type="OMA" id="WATTIDS"/>
    <dbReference type="OrthoDB" id="1818437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="3"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="201" mass="21717" checksum="06350922D1ADF2DD" modified="2010-04-20" version="1">MTTRIAVITGSTRPGRRGALVADWVVQAAASHPAVAAGEAAVDLIDLADLNLPLLDEAMPPIMGQYEHTHTKEWAATIDSYDGFLFVVPEYNHSFPGALKNALDYLYAEWNNKAAGFVGYGPGGGIRAVEQLRLVLAELKIAAVRDQVVIGKHDHADLFYQGVWTPTDETHAALELVLTETLEWAEALKTVRAKAKTLAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZH2</accession>
    <name>D3PZH2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017217.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1950"/>
    <dbReference type="EnsemblBacteria" id="ADD41646">
        <property type="protein sequence ID" value="ADD41646"/>
        <property type="gene ID" value="Snas_1950"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1950"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_4_2_11"/>
    <dbReference type="OMA" id="EHTICLL"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="152" mass="16248" checksum="0EA47C99757C9799" modified="2010-04-20" version="1">MAKSKSVALSDTATFQLGTLGAIITERFAAEMTKLDLKPKHVGVLNALSLYQATSQLELARLMGVAPSLLVALADHLEEHGAIERVRDAGDRRRQVLALTESGRALLDRCAEVAAGLETELLSTLTAQDRDALRRGLRAMATGFGLRGPEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZS8</accession>
    <name>D3PZS8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">5 nucleotidase deoxy cytosolic type C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'(3')-deoxyribonucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019186.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3963"/>
    <dbReference type="EnsemblBacteria" id="ADD43615">
        <property type="protein sequence ID" value="ADD43615"/>
        <property type="gene ID" value="Snas_3963"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3963"/>
    <dbReference type="eggNOG" id="COG0546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1352634_0_0_11"/>
    <dbReference type="OMA" id="GVCADFY"/>
    <dbReference type="OrthoDB" id="1822108at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010708">
        <property type="entry name" value="5'(3')-deoxyribonucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06941">
        <property type="entry name" value="NT5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="24139" checksum="F5B6916633513196" modified="2010-04-20" version="1">MNFVLGLDLDGVCADFYGRMREIVAELNEVPIDSLPGQVSFGLAEWGVDGIEEYRRIHRFAVTQRKLFDSMKPIPGAVPALRRLSNEGIHIRIITHRLFIPHFHQIAVTQTTTWLDRHGFLYHDLCFMKDKDLVDADLYVEDAEQNILRLQEQGKPVITFTNSTNVHTAAKRRAGSWQDAEAMIRETYYEYRSRSNLPLPTGPGKEPPSGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZV5</accession>
    <name>D3PZV5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019213.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3990"/>
    <dbReference type="EnsemblBacteria" id="ADD43642">
        <property type="protein sequence ID" value="ADD43642"/>
        <property type="gene ID" value="Snas_3990"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3990"/>
    <dbReference type="eggNOG" id="ENOG5031U0Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086377_1_0_11"/>
    <dbReference type="OMA" id="WASGINL"/>
    <dbReference type="OrthoDB" id="1828070at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025196">
        <property type="entry name" value="DUF4126"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13548">
        <property type="entry name" value="DUF4126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4126" evidence="2">
        <location>
            <begin position="4"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="22595" checksum="82D3859EF0D7AA34" modified="2010-04-20" version="1">MFAVLTGAGLSVSAGLNAYIPLLLVGLISKFTDQISLPPSWDWLSTWWALTVMTVLLIVEFVVDKIAVVDHVNDIIQTLIRPASGGAVLSATTAASELDEATGTAVAAIDNPTVAWIAGIALALAVHITKVVIRPMINAGTLGFGTPVASAAEDTGSFGMSLLSIFAPILAGIALIFVLIAIIFLWRARRRWKKRRADRKVAKIAERYSKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q089</accession>
    <name>D3Q089_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5992</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021189.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5992"/>
    <dbReference type="EnsemblBacteria" id="ADD45618">
        <property type="protein sequence ID" value="ADD45618"/>
        <property type="gene ID" value="Snas_5992"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5992"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_15_10_11"/>
    <dbReference type="OMA" id="MGQVQHY"/>
    <dbReference type="OrthoDB" id="1745184at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="199" mass="21628" checksum="545CC7A398F9DE91" modified="2010-04-20" version="1">MPRLVNHADRKKRLVEAVWSLAVRNGLEGVTLRKVAAEAGVSMGQVQHYYPSMSDLVQDAMRRSVLELNAKIEAGIAAIDTASAEDMLRQCLYAMVRLDEESVRLIRFSLAVVGRAMSDSSMAQMLAPADDQLRDFTAGLITAARVERGVERDADAHIDADICWAVAVSLGVDIALGHRGAESALAVLTYHIDQLLAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0I2</accession>
    <name>D3Q0I2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylhydroperoxidase like protein, AhpD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017289.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2023"/>
    <dbReference type="EnsemblBacteria" id="ADD41718">
        <property type="protein sequence ID" value="ADD41718"/>
        <property type="gene ID" value="Snas_2023"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2023"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_6_1_11"/>
    <dbReference type="OMA" id="CAVCIDM"/>
    <dbReference type="OrthoDB" id="1893149at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="18"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="158" mass="16942" checksum="65ED46A67FFF8D28" modified="2010-04-20" version="1">MDARLNLFANPLGGKMLKHFVSAGKVAMDSTVPRATIELVQLRASQINGCGHCIDIHTKEAVAAGESHDRLHLVAAWREATVFTDAERAALELAEQGTRIADAAGGVSDNAWANARKHYDEDELAVLVFAIAGINAFNRLNVIVQNPGGDYRAGQLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0M3</accession>
    <name>D3Q0M3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2065"/>
    <dbReference type="EnsemblBacteria" id="ADD41759">
        <property type="protein sequence ID" value="ADD41759"/>
        <property type="gene ID" value="Snas_2065"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2065"/>
    <dbReference type="HOGENOM" id="CLU_1626055_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="163" mass="17315" checksum="36D3136A721C09C8" modified="2010-04-20" version="1">MFHNRLPRSASSAAKQGFSVPSHSRPARVAVLTMSSSPMTTTPTGRGRLGGFNSRAATNRRTVAPKVSASRSTSAASSGENGLLPRARNRISPPHEIPLLVSRIRISLPIPALVISRNRTRCRGSGKPAVSTDTRPGSVNELANGYDTPSRASARSSRRMAVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0N3</accession>
    <name>D3Q0N3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017340.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2075"/>
    <dbReference type="EnsemblBacteria" id="ADD41769">
        <property type="protein sequence ID" value="ADD41769"/>
        <property type="gene ID" value="Snas_2075"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2075"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_4_4_11"/>
    <dbReference type="OMA" id="AFVTRQS"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="150" mass="16130" checksum="D8EFE29A8D5FF469" modified="2010-04-20" version="1">MSEPSESPQLEQRMGYVLKQVQAALHGAMDERLRGHGLSVAQYACLELLAETPGLSNAELARGAFVTRQAMNTVLRGLLAAGHVDRPAEAEYGRARPARLTDAGEALLAAARADVVAIEERMVTGLPRRRRRELLAELAAMARNLSGDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0P2</accession>
    <name>D3Q0P2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2084</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017349.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2084"/>
    <dbReference type="EnsemblBacteria" id="ADD41778">
        <property type="protein sequence ID" value="ADD41778"/>
        <property type="gene ID" value="Snas_2084"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2084"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_22_0_11"/>
    <dbReference type="OMA" id="DSISWAM"/>
    <dbReference type="OrthoDB" id="1335404at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="13"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="110"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="290" mass="31631" checksum="2F1415ED89BF7817" modified="2010-04-20" version="1">MTLTGSLAEADWESHRSAVFGAAYRILGTVTDAEDVTQEVWLRADTSDLSGVRDLRAWLVTVAARTSYNLLKSARVRRESYVGPWLPEPLLTGPDAADRVLLDESVSTAMLVVMEKLSPAERVALVLHDVFDFPFGRIAEVLGGTPAASRKLASRARARVAEAKERPRASKAETERVLRAFKAATDAGDLTALVTLLDPDAVYVGDGGDKVRAARRPVVGAEAIARLTIRVAGMMRPDAFRIIEVNGQPALASYRDDRLVWVDTVETSDGRITAFRRLANPEKFAHIGHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0S3</accession>
    <name>D3Q0S3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dak phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017380.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2115"/>
    <dbReference type="EnsemblBacteria" id="ADD41809">
        <property type="protein sequence ID" value="ADD41809"/>
        <property type="gene ID" value="Snas_2115"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2115"/>
    <dbReference type="eggNOG" id="COG1461">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017496_0_1_11"/>
    <dbReference type="OMA" id="TRTIPQG"/>
    <dbReference type="OrthoDB" id="1554133at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019986">
        <property type="entry name" value="DAK2_dom-cont_prot_YloV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033470">
        <property type="entry name" value="UPF_DhaK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13684">
        <property type="entry name" value="Dak1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01121">
        <property type="entry name" value="Dak1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="SSF101473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03599">
        <property type="entry name" value="YloV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DhaL" evidence="1">
        <location>
            <begin position="4"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="545" mass="55553" checksum="77FC5C6E79CEA6DB" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Z8</accession>
    <name>D3Q0Z8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019319.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4097"/>
    <dbReference type="EnsemblBacteria" id="ADD43748">
        <property type="protein sequence ID" value="ADD43748"/>
        <property type="gene ID" value="Snas_4097"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4097"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060131_7_2_11"/>
    <dbReference type="OMA" id="DYPFTRH"/>
    <dbReference type="OrthoDB" id="1972497at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="200" mass="21463" checksum="A015F28DDBDA8B22" modified="2010-04-20" version="1">MTPRIREATPADIEPAVATLSAAFADYPFTRHTLAADDHLTRLADMQRLFITHIGLPHGRVWVSDNAHAVAVWTTPESTAIAEVFTDFAPQLAHIAGDRAAISARTESALAPHRPTTPTWFLGTVGVHPESQGQGLGKAVIEPGLRAADATGTEAFLETSLASNVTLYRKLGFDIVAEIDLPDDGPKTWAMRRKPAPTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1F1</accession>
    <name>D3Q1F1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6107"/>
    <dbReference type="EnsemblBacteria" id="ADD45731">
        <property type="protein sequence ID" value="ADD45731"/>
        <property type="gene ID" value="Snas_6107"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6107"/>
    <dbReference type="eggNOG" id="COG1247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043786_0_0_11"/>
    <dbReference type="OMA" id="WNAESND"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="341" mass="38909" checksum="36D5FA73234EEC97" modified="2010-04-20" version="1">MTDIEITVLDPLEPDDVDGAMETAELSIREDVPDFPALSRAEFIVRMTRRSKSHRKHRLIAKVDGTVVGYASLHIPLLENRHLIEFELEVRPDHRRRGIGSALLAEIERYARADDRTTLLVYIPDTIDGRPQLPHNGQHFAAKQGFEKKSQEIRRAADLTEVDDAALDELLAKSWTKAEGYELIQWINDSPDDVVEALAYLDSRLVTDSPMGDLNFEAPKTDVARIRERESDGRTAGILRIATALRHKESGTVAGWTDIVVDPGDEDNCWQGITIVDPDHRGHRLGTILKIENHRHVLRYRPRMRYVTTWNAEANDFMININEAVGYRARERWLALEKDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1S6</accession>
    <name>D3Q1S6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0205</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015495.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0205"/>
    <dbReference type="EnsemblBacteria" id="ADD39924">
        <property type="protein sequence ID" value="ADD39924"/>
        <property type="gene ID" value="Snas_0205"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0205"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_1_11"/>
    <dbReference type="OMA" id="NAMFPRW"/>
    <dbReference type="OrthoDB" id="1074175at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="75"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="279" mass="30287" checksum="974C7DC638518E40" modified="2010-04-20" version="1">MASSTSKRPGIAWYTMLIGLSLVFVAPLVWMFLTSFKTRNEALAIPPTFLPEEFSTKGYQTILGDDSQAPVLTWFLNSLLAAVGHTVLVLAVASGAAYALARMEFPGKKLIFGVIISTLLIPSFVLLIPNYLIVDSLQWIDTPLALIVPGAAGAFGVFFLRQFFTSLPPDLEEAAVLDGANHFQIFVKIVLPLSKPALATLAVLSFLSNWNDFIWPIYVMFSPENMTLPPGLATLQGAYGIDYHVLMAGAVITAVPVLALFLFTQRYVIEGVSRSGLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1X7</accession>
    <name>D3Q1X7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2150</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017415.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2150"/>
    <dbReference type="EnsemblBacteria" id="ADD41844">
        <property type="protein sequence ID" value="ADD41844"/>
        <property type="gene ID" value="Snas_2150"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2150"/>
    <dbReference type="eggNOG" id="COG3973">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010312_3_1_11"/>
    <dbReference type="OMA" id="LAWLPMT"/>
    <dbReference type="OrthoDB" id="114076at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027785">
        <property type="entry name" value="UvrD-like_helicase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13538">
        <property type="entry name" value="UvrD_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="6">
        <location>
            <begin position="185"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="206"/>
            <end position="213"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="746" mass="81617" checksum="D0ED83016793EAE0" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1Z9</accession>
    <name>D3Q1Z9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Coenzyme PQQ synthesis protein B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Pyrroloquinoline quinone biosynthesis protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pqqB</name>
        <name evidence="8" type="ordered locus">Snas_2174</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">May be involved in the transport of PQQ or its precursor to the periplasm.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PqqB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017437.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2174"/>
    <dbReference type="EnsemblBacteria" id="ADD41866">
        <property type="protein sequence ID" value="ADD41866"/>
        <property type="gene ID" value="Snas_2174"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2174"/>
    <dbReference type="eggNOG" id="COG1235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061120_0_0_11"/>
    <dbReference type="OMA" id="FYIPGCA"/>
    <dbReference type="OrthoDB" id="1712770at2"/>
    <dbReference type="UniPathway" id="UPA00539"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018189">
        <property type="term" value="P:pyrroloquinoline quinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00653">
        <property type="entry name" value="PQQ_syn_PqqB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011842">
        <property type="entry name" value="PQQ_synth_PqqB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0884">PQQ biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Lactamase_B" evidence="7">
        <location>
            <begin position="50"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="294" mass="32128" checksum="C9079908D847473F" modified="2010-04-20" version="1">MKAILLGTAAGGGFPQWNCACPQCVKCRSGDPRVPSRTQDGLAISTDGERWLLVNASPDLRYQITRTKALAPGPGRRETPIEGVLLTDGELDHTLGLLTLREHAGLKVWAPATVLSALQNDFPIQDVIHRYNAWEWRELESTICGFTVETFGLGRKRPKYAVGSFAEGDWVVAYRFIDAESGGVLVYAPCLSQWPPGFDTWLDSAGCVIVDGTFYSPAEMAPSGVDTAKQAAMGHLPIDGEDGSLVRARAHRGSHWIYTHLNNTNPVLDKNSAEYRRVRHSGADVPVDGTVLEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q235</accession>
    <name>D3Q235_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cation diffusion facilitator family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2211</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017473.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2211"/>
    <dbReference type="EnsemblBacteria" id="ADD41902">
        <property type="protein sequence ID" value="ADD41902"/>
        <property type="gene ID" value="Snas_2211"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2211"/>
    <dbReference type="eggNOG" id="COG1230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013430_0_0_11"/>
    <dbReference type="OMA" id="GHEKMLH"/>
    <dbReference type="OrthoDB" id="948593at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="302" mass="31957" checksum="F3B5F34C94CF715E" modified="2010-04-20" version="1">MGAGHDHGAKSLGEKHRYRLWIALAITVTYMLVQIVAGLMTNSLALLSDAAHMGTDALGTGMALAAIIAVGRAAAHPLRTFGLYRLEVLAALANTVLLFGVAIWVGYESIQRFSEPPEVASIPLLIVASFGLIANLVSLSLLRSGAKESLNVRGAYFEVMGDLLGSIGVIAAAIVIATTGWYYADPIIAMAMAAFILPRAAKLGRDALRILLQTAPAHLDLKAVTRSLADVDGVEDVHDLHVWTLTSGMDVASAHLSISADAVLGEVLAAARQRLETDYDIKHATLQVEPSASDKACEQPSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2H8</accession>
    <name>D3Q2H8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S12 methylthiotransferase RimO</fullName>
            <shortName evidence="7">S12 MTTase</shortName>
            <shortName evidence="7">S12 methylthiotransferase</shortName>
            <ecNumber evidence="7">2.8.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ribosome maturation factor RimO</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rimO</name>
        <name evidence="10" type="ordered locus">Snas_4262</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 2 S-adenosyl-L-methionine = 3-methylsulfanyl-L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37087"/>
            <dbReference type="Rhea" id="RHEA-COMP:10460"/>
            <dbReference type="Rhea" id="RHEA-COMP:10461"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:29961"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:73599"/>
            <dbReference type="EC" id="2.8.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methylthiotransferase family. RimO subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.4" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019482.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4262"/>
    <dbReference type="EnsemblBacteria" id="ADD43911">
        <property type="protein sequence ID" value="ADD43911"/>
        <property type="gene ID" value="Snas_4262"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4262"/>
    <dbReference type="eggNOG" id="COG0621">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018697_0_1_11"/>
    <dbReference type="OMA" id="YLQPAEM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103039">
        <property type="term" value="F:protein methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018339">
        <property type="term" value="P:peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01865">
        <property type="entry name" value="MTTase_RimO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005840">
        <property type="entry name" value="Ribosomal_S12_MeSTrfase_RimO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041582">
        <property type="entry name" value="RimO_TRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43837">
        <property type="entry name" value="PTHR43837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18693">
        <property type="entry name" value="TRAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00274">
        <property type="entry name" value="ribosomal_protein_S12_methylth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01125">
        <property type="entry name" value="TIGR01125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="8">
        <location>
            <begin position="11"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="9">
        <location>
            <begin position="176"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="479" mass="50970" checksum="9D11336710D7C403" modified="2010-04-20" version="1">MSETPPVPSSRRVAVVTLGCARNDVDSEELAARLANGGWEVTDDGSDADVVMVNTCGFIETAKQDSIDMLLEASDTGAKVVATGCLAERYGTQLADSLPEADAVLGFDHYPDIAARLDAIARGEKIASHTPTDRRTLLPISPVKRREATAVIPGHAAPDTDDTAMPAHLKVMRRRLTSGPVANLKIASGCDRRCAFCAIPSFRGAFVSRDPGEILAEAQWLAEQGVVEVTLVSENTTSYGKDLSDAAALEKLLPQLAAVDGIERVRVSYLQPAELRPSLVETIATTPGVAPYFDLSFQHSSRDLLRRMRRFGSTEGFLELLETIRGLSPLAGVRTNVIVGFPGETDADAAELERFLSQARLDAVGVFSYSDEDGTEAADLDGHVDEDVIVKRHDHISVLAEEVTAQRAAERIGETVSVVVDSADDSGVDGRAAHQAPEVDGSTALIGEVDGLRPGDIVSATVVDSIGVDLVAEYRAAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2I9</accession>
    <name>D3Q2I9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <shortName evidence="9">HTPA synthase</shortName>
            <ecNumber evidence="4 9">4.3.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapA</name>
        <name evidence="11" type="ordered locus">Snas_4273</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:34171"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="4.3.3.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="4 9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019493.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4273"/>
    <dbReference type="EnsemblBacteria" id="ADD43922">
        <property type="protein sequence ID" value="ADD43922"/>
        <property type="gene ID" value="Snas_4273"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4273"/>
    <dbReference type="eggNOG" id="COG0329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_7_1_11"/>
    <dbReference type="OMA" id="GMDACVP"/>
    <dbReference type="OrthoDB" id="1438588at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00950">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00418">
        <property type="entry name" value="DapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005263">
        <property type="entry name" value="DapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020624">
        <property type="entry name" value="Schiff_base-form_aldolases_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00674">
        <property type="entry name" value="dapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00665">
        <property type="entry name" value="DHDPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD43922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="299" mass="32052" checksum="6E4594813C34C4C5" modified="2010-04-20" version="1">MTRQDANRPFGRLLTAMITPFHADGSLDVDGAKRLATYLVDEQRCDGLVVNGTTGESPTTTDEEKAAVVKAVVEAVGDRASVVAGAGTYDTAHSVKLIKRMEDAGAHGLLLVTPYYSRPLQDMLYRHFTTLADAASTPIMLYDIPPRSARELERDTIVKLAAHPRVVAVKDATQRLYDAQRKRVESGLPYYNGVDDINLAAYASGQVGAVSVIAHLVGKQLTEMFDAHDSGDVARARQISDDLLPAVWALQDSTQGLCAVKSALAARGLPAGPPRAPLYAAEPETSALIESLLKEAKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2N8</accession>
    <name>D3Q2N8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">o-succinylbenzoate synthase</fullName>
            <shortName evidence="3">OSB synthase</shortName>
            <shortName evidence="3">OSBS</shortName>
            <ecNumber evidence="2 3">4.2.1.113</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">4-(2'-carboxyphenyl)-4-oxybutyric acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">o-succinylbenzoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">menC</name>
        <name evidence="5" type="ordered locus">Snas_6166</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate = 2-succinylbenzoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10196"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18325"/>
            <dbReference type="ChEBI" id="CHEBI:58689"/>
            <dbReference type="EC" id="4.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 4/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.113" evidence="2 3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021360.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6166"/>
    <dbReference type="EnsemblBacteria" id="ADD45789">
        <property type="protein sequence ID" value="ADD45789"/>
        <property type="gene ID" value="Snas_6166"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6166"/>
    <dbReference type="eggNOG" id="COG4948">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030273_4_4_11"/>
    <dbReference type="OMA" id="GRQDEWF"/>
    <dbReference type="OrthoDB" id="951991at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043748">
        <property type="term" value="F:O-succinylbenzoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03317">
        <property type="entry name" value="NAAAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01933">
        <property type="entry name" value="MenC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010197">
        <property type="entry name" value="OSB_synthase_MenC_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48073:SF5">
        <property type="entry name" value="PTHR48073:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01928">
        <property type="entry name" value="menC_lowGC/arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="4">
        <location>
            <begin position="142"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="371" mass="40256" checksum="CD32E2D183AF8950" modified="2010-04-20" version="1">MRIEGLELHRVTLELITPFDSAYGRETHRELVLLRLVTSEGEGWGECVADTTPWFSSEYHDGAIDMIANHFLPALCAAPLPSAHAVAPRLARFKGNYMAKAAIEMAVLDTELRALGMPLGRYLGAVHETVPAGVSVGMADTVDELVDDVAGYLEQGYHRIKLKIKPGWDVAPVRAARERFGDELELQVDGNTSYRLSDAEHLARLDDFGLRLIEQPLPDEDLLGHARLAKRLRTPICLDESIVSAKSAADAITLGAASIVNIKPGRVGGYLEARRVHDMCAAHGVPVWCGGMLETGIGQSANIALAALPNFTLPGDTSASDRYFTRDLVDVRLEPGGMVRVPTGPGIGVIPDPDALTDLTTWRKWIDAPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2P4</accession>
    <name>D3Q2P4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_6172</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021366.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6172"/>
    <dbReference type="EnsemblBacteria" id="ADD45795">
        <property type="protein sequence ID" value="ADD45795"/>
        <property type="gene ID" value="Snas_6172"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6172"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_3_2_11"/>
    <dbReference type="OMA" id="HSLACAF"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="211" mass="21947" checksum="5B0B32E902F1B598" modified="2010-04-20" version="1">MMSTAQLLAFTAMAFVVIVVPGPSVLFIVGKALAHGRRYAMASLAGNTLGAFVLVLLVAFGVGTVVEKSIVALMVLKLAGAAYLIFLGVKAWRARGATTSFDSGGRQRGAFRTSVDGFVVGVTNPKTLVFFTAALPQFVDPHSGWVPLQMLLLGLIFLGIAAISDATWGMAAAAARNWFGRSPRRMRTVGGAGGISMITLGVTLAVTGNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2R5</accession>
    <name>D3Q2R5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6193</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021387.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6193"/>
    <dbReference type="CAZy" id="GH43">
        <property type="family name" value="Glycoside Hydrolase Family 43"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45816">
        <property type="protein sequence ID" value="ADD45816"/>
        <property type="gene ID" value="Snas_6193"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6193"/>
    <dbReference type="eggNOG" id="COG3940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009397_2_2_11"/>
    <dbReference type="OMA" id="YSTCDTG"/>
    <dbReference type="OrthoDB" id="386120at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048820" evidence="4">
        <location>
            <begin position="43"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="340"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="502" mass="54784" checksum="36520A4DF9C37055" modified="2010-04-20" version="1">MTSLKARIAPRRWLSAVKRRWRTATIVGVAALALTTTAVVWAQPGTEGEKDKDSQATGEFRNPLNGGADPTVVYHNENYYLSTTQGDRISIWKAKSLADLITAPKKDVYTESDPSRNQQMWAPALKRYETADGPRWYLYYTASDGVDANHRMHVLESEGDDPEGPYHYKAKIADFGAYGIDGEPFELNGKSYFIWTGPGRGQGGPAQLYISPMTDPWTTTGDRVAIPADGGCSEVREGPTPLRGNGKTFLTYSTCDTGKPDYQLWMKSIADGADPMNPDSWVQHPGPVFSRNDAAGVFGPGHHFFFKSPDGKEDWIAYHGKNTSDYTYSFRTTRAQKIGWNDDGTPNLGAPLPAGETQKLPSGDPGPGTRAINDGDIGDGDFQVKYAGNWKSGNGCASQCFKGDDHFSQEKGATVTFTFTGSQIALFSVRDVGNGYATFSIDGGPESDKIDYHSGERVGEHPNYISPKLDPGKHTLRVTVTGEKNPDSGAAYVSIDRAEVWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2S1</accession>
    <name>D3Q2S1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6199"/>
    <dbReference type="ESTHER" id="stanl-d3q2s1">
        <property type="family name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45822">
        <property type="protein sequence ID" value="ADD45822"/>
        <property type="gene ID" value="Snas_6199"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6199"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_3_11"/>
    <dbReference type="OMA" id="WEHQVAV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="46"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="296" mass="32051" checksum="27F9DF6E63EA53AF" modified="2010-04-20" version="1">MTGTVVSATESDITAMTTLPSPQRTRVTTSAGTFDAIAAGPSEGQPVLFLHGFPELSTEWAHYVALFGSLGYRAVAVDQRGYSPDARPPDPKDYHLDYLAKDVVDIADSLGWNDFHLVGHDWGAAVAWVVAARYADRIKTLCAVSVPHLGAFAKALRTDPEQQKASAYMQLLRQPGKAETVLLGEDAAALRGAYVGVPDSNVEVYVEHLSQPGALTAALNWYRVDGFDGRDEKVAVPTLFIWGTKDSAVAVSGVDDTVNWTTGEYRLEKIEGARHFTPEECPEIVGPMIQAHLESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q351</accession>
    <name>D3Q351_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trmB</name>
        <name evidence="2" type="ordered locus">Snas_0303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0303"/>
    <dbReference type="EnsemblBacteria" id="ADD40021">
        <property type="protein sequence ID" value="ADD40021"/>
        <property type="gene ID" value="Snas_0303"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0303"/>
    <dbReference type="eggNOG" id="COG0220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050910_0_1_11"/>
    <dbReference type="OMA" id="PDPWHKS"/>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01057">
        <property type="entry name" value="tRNA_methyltr_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="PTHR23417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00091">
        <property type="entry name" value="TIGR00091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="204"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="306" mass="34458" checksum="62FEF2FBCCC2432D" modified="2010-04-20" version="1">MSTIEPSSSIRSFYRRRGKVRPSKLDAYDRLYPVLGVDRQQPPPLPEIFGRTAPVVLEIGSGMGDATVAMAAADPDRDYLAVEVHVPGIANLMMRAEEHELTNLRVFEGDAVSLARSCLPADTLDAIHVFFPDPWPKARHHKRRLISPENVALLRSRLRRGGAFHLATDWEHYAESMLEVLDADPGLSNAHDGFAPRPDWRPVTKFERRGIAEGRQIFDLEFVRPEQPLSLGILAHGPQTLVPSRCRRRAARDLRVLCDHSQLGGDRRHGQARDDRTGARHRRQLLQRHGQGLQLLRGFVDAVGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q368</accession>
    <name>D3Q368_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40038">
        <property type="protein sequence ID" value="ADD40038"/>
        <property type="gene ID" value="Snas_0320"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0320"/>
    <dbReference type="HOGENOM" id="CLU_905649_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="280" mass="30551" checksum="3EA16FF383AEE6D7" modified="2010-04-20" version="1">MFASLLPGLRQLRAPLASGAAWLAVVWLWWGRHLPSRDEATGLLSDVYELTEHVGIAAVTAAMAFCAYIVGEVWEAIRGSHPAFRTTQIAEKAVSFPAFSLAPSRISKTWSAHGLLGFFTDSKAIFGDLFPNLGVKRPDSLNDEQKNELLEAMWRDINRAVSLTLDRDPELMAIYERASAEYWFRRLLAFPLGLAVGSATAASTSTWQMTVVGILVGAALWFTLNTQAQQKNGESVIAFLGAMYHEKLPCPALTEAGLRLFGPDEAGQSRTSNTGSVGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3E4</accession>
    <name>D3Q3E4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Ribokinase</fullName>
            <shortName evidence="10">RK</shortName>
            <ecNumber evidence="3 10">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rbsK</name>
        <name evidence="13" type="ordered locus">Snas_2296</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + D-ribose = ADP + D-ribose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carbohydrate kinase pfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="3 10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017556.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2296"/>
    <dbReference type="EnsemblBacteria" id="ADD41985">
        <property type="protein sequence ID" value="ADD41985"/>
        <property type="gene ID" value="Snas_2296"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2296"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_2_0_11"/>
    <dbReference type="OMA" id="AMDSIPF"/>
    <dbReference type="OrthoDB" id="1030724at2"/>
    <dbReference type="UniPathway" id="UPA00916">
        <property type="reaction ID" value="UER00889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="D_ribokin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="12">
        <location>
            <begin position="2"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="10"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="38"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="212"/>
            <end position="217"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="244"/>
            <end position="245"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD41985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="306" mass="30693" checksum="F7231093916A3ADC" modified="2010-04-20" version="1">MSVVVLGSANLDLVYDVDRIPAPGETVLSRSFESFPGGKGLNQAIAAARSGAEVHFLVALGKDAAGDRLAAEARDAGIDLRDRRVDAPTGTAVIYVDRDGENSIVVNSGANATLVDLTEAEVAAIAAANLLVLQMETPPTTVRAAARVAKANGTTVILNAAPSGSVPAALLGEVDILIVNEHEAADLAGQTADAPDQSLSALTTHGCAVIVTLGAAGSLVGAPGQPTAKIPAITVTPIDTTGAGDAFVGAFAAALDNSGRATNPDLRTLIGATEFATTAAGIAVQRKGAVPSIPTLEEVRLHSAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3W5</accession>
    <name>D3Q3W5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019603.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4385"/>
    <dbReference type="EnsemblBacteria" id="ADD44032">
        <property type="protein sequence ID" value="ADD44032"/>
        <property type="gene ID" value="Snas_4385"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4385"/>
    <dbReference type="HOGENOM" id="CLU_2208434_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="107" mass="11410" checksum="84795CD3E174CC02" modified="2010-04-20" version="1">MKINKNWYRGEASFQPIAVSTFRSRGMAGSAFAVVSRVANACPANAMHQGTSLSTAERIVLLGHDSVQTTTANTALKSRTDKPAGIVQRDGMGAPRGIPPRSKPKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q412</accession>
    <name>D3Q412_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021468.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6277"/>
    <dbReference type="EnsemblBacteria" id="ADD45897">
        <property type="protein sequence ID" value="ADD45897"/>
        <property type="gene ID" value="Snas_6277"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6277"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076095_0_1_11"/>
    <dbReference type="OMA" id="RRMPRQQ"/>
    <dbReference type="OrthoDB" id="1919329at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="23602" checksum="9A88ECB7BF24D637" modified="2010-04-20" version="1">MDNVKHPPGRSYGQFCGLARALDTVGDRWNLLIVRDLLVGPMRFNELVAALHGIATNLLSQRLRTLETAGIVERRLGDAGVLYALTPWGAGLREPIEALARWGTPLMMTGRDDDAFEPRWLGVALPGLLRGVTATPALEIGFEVDGVLTVVHIDEDGPRAEARPDRRPDTVFTAAAEIIIGLAAGGITVDQALAAGHLEGDPRVLRRAMPPLRRTRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q424</accession>
    <name>D3Q424_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_6289</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021480.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6289"/>
    <dbReference type="EnsemblBacteria" id="ADD45909">
        <property type="protein sequence ID" value="ADD45909"/>
        <property type="gene ID" value="Snas_6289"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6289"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_4_11"/>
    <dbReference type="OMA" id="MSVMMAT"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="26"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="343"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="375"/>
            <end position="382"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD45909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="584" mass="61848" checksum="4FBB15E8F1E6B2D8" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4L3</accession>
    <name>D3Q4L3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40173">
        <property type="protein sequence ID" value="ADD40173"/>
        <property type="gene ID" value="Snas_0458"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0458"/>
    <dbReference type="HOGENOM" id="CLU_1106580_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="251" mass="27413" checksum="7513019C14C4513B" modified="2010-04-20" version="1">MIDGELLAIAQQKIANLHTVDPDRVPVDAVMALWELHSGGSQLGNVESCYVMSECFGLLGVQTEFVPVALTIARWRTEEIVACYGKISPTDPRAESWHFLLRVRKLSALCDPSSPALPELAGVAGARHVAQFPVGDWDRVGGIVVARGETMLVYQPVNAAPHDVWQQSATTIDRLHCANLGSCLAAEVLDALRWNSQVARLDSQRWARVRSMIAAIGDAPLRITDGMHRAFQMPGGEMITVKDLARSDYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Y9</accession>
    <name>D3Q4Y9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2486"/>
    <dbReference type="EnsemblBacteria" id="ADD42169">
        <property type="protein sequence ID" value="ADD42169"/>
        <property type="gene ID" value="Snas_2486"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2486"/>
    <dbReference type="eggNOG" id="COG2852">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052626_3_3_11"/>
    <dbReference type="OMA" id="WTDIRVT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="309" mass="34654" checksum="DAA833CD022DCEB3" modified="2010-04-20" version="1">MFSLPGQSLGAGLSERVGELAAELPLAAVFGLRTAAWLHGLDVLPRSVSNDCWPVEVVVPKGVELASRRGLRVYRWGLGTDVEQIGDVLVTTKARTALDCARVLPRLDAVSAVDQFLRGGLELAELRRRAAIVGDRGSARLMGAVLDVADTRAESPLESWARCLIVDAGLPRPVAQLPVGLRDGSIVHLDLGYRRFRVGIECNGLRYHATDDMREHDRQRRKRLESEGWLMFTLYGSDVVVSPDDMLAEIRWRLRHRGWKPSELQLERVEKRVRYLAMALRLEREDWNAAWGLGLSRRMPRSRYITSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q578</accession>
    <name>D3Q578_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4482</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4482"/>
    <dbReference type="EnsemblBacteria" id="ADD44127">
        <property type="protein sequence ID" value="ADD44127"/>
        <property type="gene ID" value="Snas_4482"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4482"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="PGCLTIV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="851"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="941" mass="103717" checksum="66EA299C45A5508A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q586</accession>
    <name>D3Q586_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nicotinamide mononucleotide transporter PnuC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4490</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019706.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4490"/>
    <dbReference type="EnsemblBacteria" id="ADD44135">
        <property type="protein sequence ID" value="ADD44135"/>
        <property type="gene ID" value="Snas_4490"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4490"/>
    <dbReference type="eggNOG" id="COG3201">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076589_2_0_11"/>
    <dbReference type="OMA" id="WPIGIAN"/>
    <dbReference type="OrthoDB" id="1301128at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034257">
        <property type="term" value="F:nicotinamide riboside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006419">
        <property type="entry name" value="NMN_transpt_PnuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36122">
        <property type="entry name" value="PTHR36122"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04973">
        <property type="entry name" value="NMN_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01528">
        <property type="entry name" value="NMN_trans_PnuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="214" mass="23620" checksum="62798BBB0554FA03" modified="2010-04-20" version="1">MNIADLVAALQQPLFTVLATPVSWTEVLGFGSGALCVWLVARQHIANWPTGIANNLFFILLFTQAGLYADAGLQLVFITLAVYGWWNWARRGSGAVTVVVRRTTRVEWYVLGVAGVAGLVGLTWLLDSATDSTVPFWDALTTVLSLLATYGQCRKRLESWWLWIAADVVYIPLYAYKGLYLTAILYVGFMALCVMGLRGWRRDLVAARPAEAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5M6</accession>
    <name>D3Q5M6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_6471</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021657.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6471"/>
    <dbReference type="EnsemblBacteria" id="ADD46086">
        <property type="protein sequence ID" value="ADD46086"/>
        <property type="gene ID" value="Snas_6471"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6471"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_135_2_11"/>
    <dbReference type="OMA" id="RKSSSWV"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03793">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00740">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51178">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="12"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="10">
        <location>
            <begin position="348"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="10">
        <location>
            <begin position="415"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="10">
        <location>
            <begin position="481"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="10">
        <location>
            <begin position="551"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="573"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD46086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="613" mass="65685" checksum="BCDC019D5389C6D8" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5X2</accession>
    <name>D3Q5X2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphoserine transaminase</fullName>
            <ecNumber evidence="6">2.6.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phosphohydroxythreonine aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_0557</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16573"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015842.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0557"/>
    <dbReference type="EnsemblBacteria" id="ADD40271">
        <property type="protein sequence ID" value="ADD40271"/>
        <property type="gene ID" value="Snas_0557"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0557"/>
    <dbReference type="eggNOG" id="COG1932">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061974_0_0_11"/>
    <dbReference type="OMA" id="TAFWDIA"/>
    <dbReference type="OrthoDB" id="996960at2"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00197"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006272">
        <property type="entry name" value="Pser_aminoTfrase_mycobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01366">
        <property type="entry name" value="serC_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0718">Serine biosynthesis</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="9">
        <location>
            <begin position="138"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD40271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="369" mass="39120" checksum="100C08E0FF09801B" modified="2010-04-20" version="1">MADIRIPTNLLPADGRFGSGPSKVPAAAITALAQAAPDFLGTSHRQARVRDQVARLRRGLSDFFRLPDGYEVVLGNGGTTAFWEAAVFGLVRETAQVASFGEFGAKFAKAIKTAPFVGDPTVITAEPGTAAYLSQQDGVDVYATPHNETSTGVAIDVKRVPGDGLMLHDATSAAGGLNFDVTETDVYYLAPQKGLASDGGLWIALMSPAALTRVEQIAASGRYIPEFLNLSTAVDNSRKEQTYNTPALATIFLAAEQVDTMNAAGGLDAAAARCADSADRLYTWAEKSPVASPFVTDPNLRSNVVATIDFADSVDAKELAKVLRANGVLDTEPYRKLGRNQLRIAMYPAIDPDDISALTACVDHVIDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5X8</accession>
    <name>D3Q5X8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">[Ribosomal protein S18]-alanine N-acetyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.266</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acetylates the N-terminal alanine of ribosomal protein S18.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + N-terminal L-alanyl-[ribosomal protein bS18] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-alanyl-[ribosomal protein bS18]</text>
            <dbReference type="Rhea" id="RHEA:43756"/>
            <dbReference type="Rhea" id="RHEA-COMP:10676"/>
            <dbReference type="Rhea" id="RHEA-COMP:10677"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64718"/>
            <dbReference type="ChEBI" id="CHEBI:83683"/>
            <dbReference type="EC" id="2.3.1.266"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyltransferase family. RimI subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.266" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0563"/>
    <dbReference type="EnsemblBacteria" id="ADD40277">
        <property type="protein sequence ID" value="ADD40277"/>
        <property type="gene ID" value="Snas_0563"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0563"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_23_3_11"/>
    <dbReference type="OMA" id="FEPIGFR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006474">
        <property type="term" value="P:N-terminal protein amino acid acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006464">
        <property type="entry name" value="AcTrfase_RimI/Ard1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01575">
        <property type="entry name" value="rimI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="149" mass="16734" checksum="618A358BCA971288" modified="2010-04-20" version="1">MPDWDIAPLRWWHIEQLLPIEDELFGAEAWNAAMFWSELAAGHYYRVVLDDERVLGYAGLALSGDDGWVNNIAVRKAAQRRGVARALLNDLIGRAEGQGVRRLALEVAVDNAAAQRLYDAFGFEGVAIRKGYYQPSNTDAVVMMKELRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q646</accession>
    <name>D3Q646_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">(2Fe-2S)-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017792.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2540"/>
    <dbReference type="EnsemblBacteria" id="ADD42221">
        <property type="protein sequence ID" value="ADD42221"/>
        <property type="gene ID" value="Snas_2540"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2540"/>
    <dbReference type="eggNOG" id="COG2080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052511_3_1_11"/>
    <dbReference type="OMA" id="QEADDVW"/>
    <dbReference type="OrthoDB" id="1843415at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="157" mass="16673" checksum="210D359A5064AD71" modified="2010-04-20" version="1">MRVKFTVNGSPVTVDDVWPGESLLYVLRERAGYPGAKNACEQGECGSCTVYLDDEPVCSCLVAAPQAEGREVRTVEGLAEKADTDLAEIQKAFVEAGAVQCGFCTPGLLVSADDLLNKSAEPSDAEIREALAGNLCRCTGYEKILDAVRLAATRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6H0</accession>
    <name>D3Q6H0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019784.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4569"/>
    <dbReference type="EnsemblBacteria" id="ADD44213">
        <property type="protein sequence ID" value="ADD44213"/>
        <property type="gene ID" value="Snas_4569"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4569"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_18_2_11"/>
    <dbReference type="OMA" id="WGERQAV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="3"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="124" mass="13476" checksum="BD5734563290FD7B" modified="2010-04-20" version="1">MITEAFPMLTTPDLKRALGFYRDLLGGEVYYQFPAEGEPMYVTLRCGSSSLGIGEDTETAGRNRDSGVFSLCVYVDDVDAALKRLGDAHAVILSPAVDQPWGERMAEVADPDGTRIVLMSKLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6J7</accession>
    <name>D3Q6J7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4596</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019811.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4596"/>
    <dbReference type="EnsemblBacteria" id="ADD44240">
        <property type="protein sequence ID" value="ADD44240"/>
        <property type="gene ID" value="Snas_4596"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4596"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_9_2_11"/>
    <dbReference type="OMA" id="CGDRGTA"/>
    <dbReference type="OrthoDB" id="1992113at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="19"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="120"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="186" mass="20606" checksum="35577403379425D4" modified="2010-04-20" version="1">MTSVTVSRIGSDPDALEEFYREHVGSIQGFIARRVDDSHLVADLTAEVFLAAIDSAHKYRPGKGTPAGWLYGIARNVVADERRRLVRAMTANQRISGRALVEPDDLSALDDRIDAEAQSRRLYEAMDRLSEAERAVLELVALDGLSVRDAAAALRIRPTTARVRLHRARKTMRDHLDPRVPAIVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6N8</accession>
    <name>D3Q6N8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4638"/>
    <dbReference type="EnsemblBacteria" id="ADD44281">
        <property type="protein sequence ID" value="ADD44281"/>
        <property type="gene ID" value="Snas_4638"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4638"/>
    <dbReference type="eggNOG" id="ENOG5033P1U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120923_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019660">
        <property type="entry name" value="Put_sensory_transdc_reg_YbjN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10722">
        <property type="entry name" value="YbjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="24155" checksum="A8DCBB1D5194DADF" modified="2010-04-20" version="1">MAWWRKRPETRASGYDDAKRREPQPAAIPAPREEMTTPSNPDDRWDIIKQDLIALDPDFFNDLEQLTDEVPTQKSAELTDERLIASLRRLNIRYLVDEAGALLAMWERHVVQIRREGPAGEILVLRARAYSTLPAEWNDRAFRAVNEWNRTRRFLKAYVGEPTESGSVPLYGETQVPLRPGVPDDLLDEFVDCAAAVSGAYIDWLHGEAGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6P6</accession>
    <name>D3Q6P6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4646</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019860.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4646"/>
    <dbReference type="EnsemblBacteria" id="ADD44289">
        <property type="protein sequence ID" value="ADD44289"/>
        <property type="gene ID" value="Snas_4646"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4646"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_11"/>
    <dbReference type="OMA" id="AWDEFLY"/>
    <dbReference type="OrthoDB" id="1510342at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="65"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="273" mass="29603" checksum="4683131260C07768" modified="2010-04-20" version="1">MVAKKFQWSLLNTVVVAFALIPVLWLVSLSLKHPSTYTDGNFFPVKPTFDNYVNVFSSGGFFQPLINSIGISLIATGIALLVGTFAAYAIARLNFPGRNLMLGAALLVAMFPQVSLVTPLFEIERNLGLFNTWLGLILPYVTFALPLTIYTMQSFFREIPWELEKAAKMDGATPFQAFRKVIVPLATPGVVTASVLAFIQVWNDFLFAISLTSTDNARTAPAAISFFTGASQFENPVGSIAAAAVIITIPIVIFVLIFQRRIVSGLTAGAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6U3</accession>
    <name>D3Q6U3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0628</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015913.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0628"/>
    <dbReference type="EnsemblBacteria" id="ADD40342">
        <property type="protein sequence ID" value="ADD40342"/>
        <property type="gene ID" value="Snas_0628"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0628"/>
    <dbReference type="eggNOG" id="COG4683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107454_1_1_11"/>
    <dbReference type="OMA" id="EFGPQLG"/>
    <dbReference type="OrthoDB" id="1733128at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="127" mass="14721" checksum="7F6C7EFBF8527F35" modified="2010-04-20" version="1">MAGNYQLRFFKDVIEWIQQLQKEDPDSFEHVIAALERLQEHGPALRRPTVGAIEGSAYRHMRELRARNGSRVSIRLLFAFDPERRAIFLVAGNKAGQRQWTVWYDKAVKEADARYAAYLDALNAEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q700</accession>
    <name>D3Q700_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anthranilate synthase</fullName>
            <ecNumber evidence="1">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0686</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate + L-glutamine = anthranilate + H(+) + L-glutamate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:21732"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="4.1.3.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015970.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0686"/>
    <dbReference type="MEROPS" id="C26.960"/>
    <dbReference type="EnsemblBacteria" id="ADD40399">
        <property type="protein sequence ID" value="ADD40399"/>
        <property type="gene ID" value="Snas_0686"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0686"/>
    <dbReference type="eggNOG" id="COG0147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0512">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006493_3_0_11"/>
    <dbReference type="OMA" id="AYRSFMN"/>
    <dbReference type="OrthoDB" id="1786019at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010112">
        <property type="entry name" value="TrpE-G_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036934">
        <property type="entry name" value="TrpE-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01815">
        <property type="entry name" value="TrpE-clade3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Chorismate_bind" evidence="4">
        <location>
            <begin position="232"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="GATase" evidence="3">
        <location>
            <begin position="520"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR036934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="706" mass="76713" checksum="C24890C736F154B5" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q730</accession>
    <name>D3Q730_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane-flanked domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0717</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016000.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0717"/>
    <dbReference type="EnsemblBacteria" id="ADD40429">
        <property type="protein sequence ID" value="ADD40429"/>
        <property type="gene ID" value="Snas_0717"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0717"/>
    <dbReference type="eggNOG" id="COG3428">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082134_0_0_11"/>
    <dbReference type="OMA" id="TDMKYEQ"/>
    <dbReference type="OrthoDB" id="1750498at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="3">
        <location>
            <begin position="144"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="255" mass="28398" checksum="73CC751119AC4300" modified="2010-04-20" version="1">MNDGKHAGDGGPAEYAEGRVTEPLDPPSQRRPSEGAAPDIAEDDLKGFRFDASGMPLGPSDMPVPDVPSPLAARYLFPTEKYRGEWRRHWIHLMPVIVIGVLATFVGGYITGVFGKGGNSTLVTGVIVVYLCILLWGAWRVFDWYFDRFILTNKRVMVINGIITRKVAMMPLLRVTDMKYEQSPLGRMMNYGSFVMESAGQDQALREVKHLPDPNELYLQICEEMYEPEAVDARDTVDESLDEPLTADNKQGGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7G8</accession>
    <name>D3Q7G8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4667</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4667"/>
    <dbReference type="EnsemblBacteria" id="ADD44310">
        <property type="protein sequence ID" value="ADD44310"/>
        <property type="gene ID" value="Snas_4667"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4667"/>
    <dbReference type="eggNOG" id="COG0572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087906_0_0_11"/>
    <dbReference type="OMA" id="HEELFGW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="204" mass="22788" checksum="B4628262BDA2EEC2" modified="2010-04-20" version="1">MRIMSFKELGGLIMDRPPRLGDVRVVAVDGRAGSGKSTFAGRLARERAQVGADVALVHTDDLLDGWGHPSNFTPYLRQWILGPLTAGGRAKYRAYDWIAKRFGTDWRDIGHPELLILEGVTTAAEQWRPTLSYSVLVDTDPGEAKRRGLERDGEAMRPEWDKWTAHEDAHFPADRTDSHVDIIVDGNPGEPHDPETEFVLVKAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7U0</accession>
    <name>D3Q7U0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0733</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016016.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0733"/>
    <dbReference type="EnsemblBacteria" id="ADD40445">
        <property type="protein sequence ID" value="ADD40445"/>
        <property type="gene ID" value="Snas_0733"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0733"/>
    <dbReference type="eggNOG" id="COG0741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059319_2_0_11"/>
    <dbReference type="OMA" id="GAMTHAK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="220" mass="23484" checksum="FFC354F512251DE4" modified="2010-04-20" version="1">MNDAPEENVEPTRKTSRGQRLRGWVTSQPRLRLGLVGVVALALVAGAWTGVSYASNGSEPAAAKPSATADAGDSQSLSPEPHPSTAPEKEKTEKEKKPKPKATEEEEKPKTEAPAPGCDGFSGNQLTACKMLDDHGFGTDQMDCLSQLWDHESGWNHQASNGSSGAYGIPQALPGDKMASAGSDWSSNPATQIEWGLGYIADRYGNPCGAWGFWQSNNYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7V7</accession>
    <name>D3Q7V7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016033.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0750"/>
    <dbReference type="EnsemblBacteria" id="ADD40462">
        <property type="protein sequence ID" value="ADD40462"/>
        <property type="gene ID" value="Snas_0750"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0750"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_20_1_11"/>
    <dbReference type="OMA" id="FHSDERQ"/>
    <dbReference type="OrthoDB" id="867226at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="7"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="485" mass="52371" checksum="05AD5C52748AAE23" modified="2010-04-20" version="1">MNRLDNDVIIVGAGPTGLLLAGDLAAAGVSVSILEKRDTESNLTRAFAVHARTLETLDMRGLADPLTQEGSKEGELLLVGRARLRLSDLDSRFPYVLITPQYRTEQLLRDRALANGARIESGVKVTELTQDGDGVELIVETAAGTQTRTAAYVVGTDGVHSVIRERLGLPFPGQLAAGSIMLADVRLSEPPPETLTVRGAREGFVFIAPFGDGWYRIVARHSRDTTPDDVPVDFEDLRSLVRHVFGTDFGMTEPRWTSRFHSDERQAPRYRVGRVFLAGDAAHVHSPAGGQGMNTGLQDAANLGWKLAAAVRGHAPEGLLDSYETERHPIGAAVLKGSGALLRLVQLRNGLVRAVRDAVMRLALRTKRIRTKAAGAVSGIAIRYPAGHGSGDAVGTRMPDIPLATVKGQSNRLYETLRGGRFVLVTGSEGPEVPENLTDLVDVVNPEDDDHTATLVRPDGYIAWRGAASETPNWSAWLRDSERVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q878</accession>
    <name>D3Q878_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemerythrin HHE cation binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018023.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2776"/>
    <dbReference type="EnsemblBacteria" id="ADD42452">
        <property type="protein sequence ID" value="ADD42452"/>
        <property type="gene ID" value="Snas_2776"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2776"/>
    <dbReference type="eggNOG" id="COG5592">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079417_2_2_11"/>
    <dbReference type="OMA" id="ERFDAKV"/>
    <dbReference type="OrthoDB" id="1701106at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="1">
        <location>
            <begin position="7"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="184" mass="20361" checksum="8E8C2434E1C26836" modified="2010-04-20" version="1">MHDNNLINVITADHRAVEAAFSELEANLTTPKQRRDLVDHVIAELVRHSVAEEQFMYPAVRKYVPGGDEMADHEIEEHAEAERVMKDLDEMDVSDPGFEIKLQELMHDIRHHVQEEETTLLPTLAAACSASELEDLGEKVLAAKKVAPTRPHPSAPDTPPANLIVAPGAGLIDRIRDALSGRQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8E5</accession>
    <name>D3Q8E5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_2844</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2844"/>
    <dbReference type="EnsemblBacteria" id="ADD42519">
        <property type="protein sequence ID" value="ADD42519"/>
        <property type="gene ID" value="Snas_2844"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2844"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002554_3_1_11"/>
    <dbReference type="OMA" id="DNLATRM"/>
    <dbReference type="OrthoDB" id="811938at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013587">
        <property type="entry name" value="Nitrate/nitrite_sensing"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08376">
        <property type="entry name" value="NIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048750" description="Histidine kinase" evidence="7">
        <location>
            <begin position="27"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="526"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="634"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="719"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="638"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="772"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="794" mass="85470" checksum="AC7383A405D0C6AA" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8M9</accession>
    <name>D3Q8M9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020042.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4830"/>
    <dbReference type="ESTHER" id="stanl-d3q8m9">
        <property type="family name" value="Monoglyceridelipase_lysophospholip"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44471">
        <property type="protein sequence ID" value="ADD44471"/>
        <property type="gene ID" value="Snas_4830"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4830"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051796_0_0_11"/>
    <dbReference type="OMA" id="HGFVDYF"/>
    <dbReference type="OrthoDB" id="1694750at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="44"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="316" mass="35763" checksum="1FCCE4D58F7F840C" modified="2010-04-20" version="1">MKPDKLGELYKHRTLYLGEDGEGEVVATLVRRVDSPNTGRAALYIHGFSDYFFHPHVADFFVERGFAFYALDLRKAGRSILPHQTPHFIRHIPEYFSELDVASKILTEEHRHDSIVVYAHSTGALTAALWAHRMRKHPWLSGMIFNSPFFEINIAELVQRLGVAPLDIAGLFAPMRVLPKLGASLNVESLHRDHKGEWDFDLAWKPLAGTPIRLGWLRAVDRAQRQLRRGLEIKVPVLVAAAADTYREAQWSDAVHTSDAVLDADDIVRWAPKLGPDVDVVRITGGRHDLALSREPARSLFFGELDSWLRSRSLMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8S9</accession>
    <name>D3Q8S9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ANTAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020092.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4880"/>
    <dbReference type="EnsemblBacteria" id="ADD44521">
        <property type="protein sequence ID" value="ADD44521"/>
        <property type="gene ID" value="Snas_4880"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4880"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074354_3_1_11"/>
    <dbReference type="OMA" id="GVIAHTH"/>
    <dbReference type="OrthoDB" id="1958442at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005561">
        <property type="entry name" value="ANTAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012074">
        <property type="entry name" value="GAF_ANTAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03861">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036625">
        <property type="entry name" value="GAF_ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01012">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50921">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ANTAR" evidence="3">
        <location>
            <begin position="169"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="252" mass="28077" checksum="B67B7F8988E9718C" modified="2010-04-20" version="1">MNAIREHRLAETFVELADTLVANFDVVDFTHVLANRCVELLDAAAVGLMLIDQHSQLRVIASSDEQSRVLELFELEADHGPCLECFRTGHQVADPDLRDADTRWPRFAAKAVEAGYLAVQAIPMRLRGETIGVLNLFRQQPGALDETLLRTGQALADVATIGLLHERAVRHHQILAEQLQGALNSRVVIEQAKGLLSERFNVDMPTAFVVMRKFARRTNRKLSDVAQDVVSGRLETRELVVPMDKATEPEPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q914</accession>
    <name>D3Q914_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycine oxidase ThiO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0912</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016194.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0912"/>
    <dbReference type="EnsemblBacteria" id="ADD40623">
        <property type="protein sequence ID" value="ADD40623"/>
        <property type="gene ID" value="Snas_0912"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0912"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_4_5_11"/>
    <dbReference type="OMA" id="CRRLEPM"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012727">
        <property type="entry name" value="Gly_oxidase_ThiO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02352">
        <property type="entry name" value="thiamin_ThiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="2">
        <location>
            <begin position="5"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="349" mass="36460" checksum="B1F97D81C3DE9C34" modified="2010-04-20" version="1">MTATDIAIAGAGIIGLSIARELTARGMTVTVHDPEPGSGASTVAAGMLAPVTESQFGEEPLSRLSLASAKLWPEFAAGLGITDAYRDTGTIFVGVDAADAAELDRQLKLYRDYGLACQPLSAAEARQHIPLLSPSVSKGLLAATDHQVDTRRVHAALLEACRAAGVNFVPRRVTDPSTVDAGLLVVAAGSWSAKLLGLPVRPVRGQVVRLRGPDELGYTVRARVRGRTVYVVPRASGEVVIGATQDDRGFDTAATAGDTNALLRDTLEVLPELAEYELAEVNVGLRPGTPDNAPLLGRTADPRVVAATGHFRQGILLAPITAALIGDLIATGTVPEALKPFDPLRFDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9H4</accession>
    <name>D3Q9H4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2982</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2982"/>
    <dbReference type="EnsemblBacteria" id="ADD42656">
        <property type="protein sequence ID" value="ADD42656"/>
        <property type="gene ID" value="Snas_2982"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2982"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_9_0_11"/>
    <dbReference type="OMA" id="WQPDFPS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048970" evidence="2">
        <location>
            <begin position="28"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="3">
        <location>
            <begin position="91"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="573" mass="63023" checksum="AFBE556E03D5CBE4" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9V1</accession>
    <name>D3Q9V1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020218.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5010"/>
    <dbReference type="EnsemblBacteria" id="ADD44647">
        <property type="protein sequence ID" value="ADD44647"/>
        <property type="gene ID" value="Snas_5010"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5010"/>
    <dbReference type="eggNOG" id="COG1359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131496_7_0_11"/>
    <dbReference type="OMA" id="GNLWFDW"/>
    <dbReference type="OrthoDB" id="1909149at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="2"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="108" mass="12314" checksum="F83A75EB08B5DD51" modified="2010-04-20" version="1">MIFITAKFRVLPQHAERWAEIAAEFTQATRSEPGCLWFDWSRSLDDSNEYVLVEAFRDQDAGAAHVQSAHFAQAQQTLPQYLAETPRIVSTSVDQEDWSELGELAVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9V7</accession>
    <name>D3Q9V7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020224.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5016"/>
    <dbReference type="EnsemblBacteria" id="ADD44653">
        <property type="protein sequence ID" value="ADD44653"/>
        <property type="gene ID" value="Snas_5016"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5016"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_28_1_11"/>
    <dbReference type="OMA" id="SWIEGAY"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16925">
        <property type="entry name" value="TetR_C_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="191" mass="20243" checksum="EDEDD809ECCF7A2B" modified="2010-04-20" version="1">MAAKGLQTRARFIEAARTLVEAKGYHGTGLNEVLALAGAPRGSFYHHFPRGKDQLIGEALAAAGQELDDMVNALAETATSSRELVAAFLEVLAERMTEADYAKGCPIATVALEVASSNPQLQAVCGGIYSAWQERLTSALLAEGRDPVEAEDLGATVLALIEGALVLARANRSRVPIERSARQIARLLGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Z0</accession>
    <name>D3Q9Z0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0992</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016273.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0992"/>
    <dbReference type="EnsemblBacteria" id="ADD40702">
        <property type="protein sequence ID" value="ADD40702"/>
        <property type="gene ID" value="Snas_0992"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0992"/>
    <dbReference type="HOGENOM" id="CLU_2304301_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="100" mass="10432" checksum="6ADCC173C42E1FEF" modified="2010-04-20" version="1">MNDLLAEVSSIQSTASSIDDAASQAMSLAGQVLGIAESTVWQGTANAAYVDAVETFREQKDKLGQLLSQISGDVDLAGVDHQTNEDEQQAGMQAKAGMMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAD0</accession>
    <name>D3QAD0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_3042</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018284.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3042"/>
    <dbReference type="EnsemblBacteria" id="ADD42713">
        <property type="protein sequence ID" value="ADD42713"/>
        <property type="gene ID" value="Snas_3042"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3042"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043648_0_0_11"/>
    <dbReference type="OMA" id="MPPLPFE"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014305">
        <property type="entry name" value="RNA_pol_sigma-G_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02960">
        <property type="entry name" value="SigX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="8">
        <location>
            <begin position="21"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="9">
        <location>
            <begin position="133"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="10">
        <location>
            <begin position="203"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD42713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="36216" checksum="1E817B0563F83B2F" modified="2010-04-20" version="1">MTSTLEAARAGDEAAFEELTRPYLRELHVHCYRMLGSFDDAEDLTQETLLSAWRGLARFAERSSLRAWLYRIATNRCLNAIRDGKRRPPPQPVAPFEPPEPNGTVEVPWLQPYPDERLDPASRYQSRETVELAFITALQTLPPRQTAALLLCDVLGYGLAEAAGMLDTSPTALKGVLQRARAAMPGPVPPEPVRADAGQARLARRFASAFEADDVDAVIALLTDDAWLTMPPAPHEYRGLAAIAQFLRIRRRWRGDRPLSLVDTRANGQPAFGCYLPDPDGRVARPTGIVVLTMRGDRIGGITRFLGSRLHRHFGLPDSFDVAERSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAD4</accession>
    <name>D3QAD4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018288.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3046"/>
    <dbReference type="EnsemblBacteria" id="ADD42717">
        <property type="protein sequence ID" value="ADD42717"/>
        <property type="gene ID" value="Snas_3046"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3046"/>
    <dbReference type="HOGENOM" id="CLU_857678_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="324" mass="35743" checksum="D817F725602984AB" modified="2010-04-20" version="1">MNEDIKTELDAELPHGRVPFALDTDKAVDLGRRTRKRRKLLATGGSVLSAVAVTGLVVTLLTPGQPSDDQAADDKTNNQDGDFPELNPKFHYQWAGGAYQNNKPPKPIDDYTAAFWKHLDSEYPDAKLSWFGGDSGNHAEGEDAVYFHREEQMLIGLEDPTDPESMPDKSIHYDRDTYSMLQWDDTPESGGASDPTFAFTEDRGTDDTLTILVFPAGTYKKDSGDVYDPAGCNNDDSFTQFESCDAEKAEGPDGQDLRQVSMKTEDDGQPPVEAERSVVYYRADGSAVVVSDEVSRTKESDPAPYLSYEQLAEFAFALPDTPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAE0</accession>
    <name>D3QAE0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translation initiation factor IF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">infC</name>
        <name evidence="8" type="ordered locus">Snas_3052</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the IF-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018294.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3052"/>
    <dbReference type="EnsemblBacteria" id="ADD42723">
        <property type="protein sequence ID" value="ADD42723"/>
        <property type="gene ID" value="Snas_3052"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3052"/>
    <dbReference type="eggNOG" id="COG0290">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054919_3_2_11"/>
    <dbReference type="OMA" id="RNMIMFL"/>
    <dbReference type="OrthoDB" id="1760144at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00080">
        <property type="entry name" value="IF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="PTHR10938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="SSF54364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="SSF55200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IF3_N" evidence="7">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="IF3_C" evidence="6">
        <location>
            <begin position="78"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="182" mass="20465" checksum="74348DB58EF3BFA1" modified="2010-04-20" version="1">MNEQIRAREVRLVGPQGEQVGIVSLDKALQLAADVDLDLVEVAPNARPPVCKLMDYGKHKYETALKAREARRNQQQTVIKEMKLRPKIDDHDYETKKGHVIRFLKAGDKVKITIMFRGREQSRPELGLRLLNKLGEEVSDLGVVEAAPKQDGRNMIMVLAPHRTKQPVATKAAKKPAEGDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAK6</accession>
    <name>D3QAK6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018360.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3118"/>
    <dbReference type="EnsemblBacteria" id="ADD42789">
        <property type="protein sequence ID" value="ADD42789"/>
        <property type="gene ID" value="Snas_3118"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3118"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_0_11"/>
    <dbReference type="OMA" id="FATDDYP"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="309" mass="32736" checksum="2F53BA694BB1D457" modified="2010-04-20" version="1">MFDENRLRVFVAVAREGSVTAAAAKLHYAQPSVSHHLARLEEEIGAPLVSRLGRGIRLTEAGRLFAERAEEILGRIDAARTELASHAGLVNGHVRLAAFPTALAALVPSAAGAFADAYPGVDVDLTEAEPPQAIAALRRGEVDICLAFHYGATPPADWEALSVAPLFDEPVYLVTSPGSSPSGPRDELASYADRRWIAGCAQCRAHLLSACEASGFTPSVAFETDDYVAVQALVAQGMGVSTLPGLALRAHRDERVRLDLLPDDRRTVVALTYGAPVAAPARAFLDILETGPAETRQWPDSSLDTASAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAM5</accession>
    <name>D3QAM5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">UvrABC system protein A</fullName>
            <shortName evidence="13">UvrA protein</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">uvrA</name>
        <name evidence="17" type="ordered locus">Snas_3137</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Forms a heterotetramer with UvrB during the search for lesions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the ABC transporter superfamily. UvrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3137"/>
    <dbReference type="EnsemblBacteria" id="ADD42808">
        <property type="protein sequence ID" value="ADD42808"/>
        <property type="gene ID" value="Snas_3137"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3137"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="1 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0742">SOS response</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="16">
        <location>
            <begin position="619"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="760"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <begin position="661"/>
            <end position="668"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023204"/>
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    </evidence>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ADD42808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="961" mass="105445" checksum="3B3FECB0D622AD05" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAN4</accession>
    <name>D3QAN4_STANL</name>
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        <submittedName>
            <fullName evidence="5">Alpha-N-acetylglucosaminidase</fullName>
            <ecNumber evidence="5">3.2.1.50</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5043</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="89"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="domain" description="NAGLU_C" evidence="4">
        <location>
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            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF05089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="696" mass="77238" checksum="432818513C46C50D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAQ8</accession>
    <name>D3QAQ8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5068</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
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            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="Snas_5068"/>
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    <dbReference type="KEGG" id="sna:Snas_5068"/>
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    <dbReference type="OMA" id="SEQHVIT"/>
    <dbReference type="Proteomes" id="UP000000844">
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    </dbReference>
    <dbReference type="GO" id="GO:0003677">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
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        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="154"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="220" mass="23239" checksum="5AEE4476E79D6F6C" modified="2010-04-20" version="1">MTSPVKVLLVDDDALVRTGLRLMFGGASGIEIVGEIGDGRDVLDTVARLRPDVVLMDIRMPHVDGIAATRALSARDTETPRVIVLTTFDADGTVVEALRAGAAGFLLKHSKPEQIVAAVHAAAAGEPVLSAEVTRTLIARVAGDGADRNRRGRARERLAVLSDKERDVARAVAKGLSNSEIGQSLYLSSGTVKAYVSSALSKLDLTNRIQLALLAHDAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAY1</accession>
    <name>D3QAY1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PDZ/DHR/GLGF domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020348.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5142"/>
    <dbReference type="EnsemblBacteria" id="ADD44777">
        <property type="protein sequence ID" value="ADD44777"/>
        <property type="gene ID" value="Snas_5142"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5142"/>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020120_3_7_11"/>
    <dbReference type="OMA" id="EIWTHKP"/>
    <dbReference type="OrthoDB" id="741829at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="517"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="598"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="614" mass="58443" checksum="140F3005C0446E8F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB04</accession>
    <name>D3QB04_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome d ubiquinol oxidase, subunit II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1111</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016392.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1111"/>
    <dbReference type="EnsemblBacteria" id="ADD40821">
        <property type="protein sequence ID" value="ADD40821"/>
        <property type="gene ID" value="Snas_1111"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1111"/>
    <dbReference type="eggNOG" id="COG1294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049294_0_1_11"/>
    <dbReference type="OMA" id="MELAWYA"/>
    <dbReference type="OrthoDB" id="761975at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00203">
        <property type="entry name" value="cydB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="338" mass="34867" checksum="67DDABFC9CA271A8" modified="2010-04-20" version="1">MILESLWLALLGVLLGGYFVLGGLDYGAQVLRLWLGGDESARRSTLGALGPFFFGNEVWLVGFAGVLFGAFPFLEGKLLSGMYPLFLAILIGLVVGKTAVQLRGRADTVRGRRVWDVLAFAGGLVPAWSWGMLVALLLRGVPIGADGHFTLTGAQLGEPFVLACGAASTALFVTHGAAFLAARVRGAAAGAARALLPRLGVVTVVASLGAGGIGVASAVDDGFAAPAAAVAVGALLPIAVVAAMVASRRGWAKTAVTATGVAALVPALLPGVAHYPRLLVSTVSERYSVTVSHAAADVETLKLLSAFGIVVVPVILLYQGWSWWAFRERVDSGSPTYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB47</accession>
    <name>D3QB47_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016435.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1154"/>
    <dbReference type="EnsemblBacteria" id="ADD40864">
        <property type="protein sequence ID" value="ADD40864"/>
        <property type="gene ID" value="Snas_1154"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1154"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_851606_0_0_11"/>
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    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="293"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="386" mass="39874" checksum="4BB44D693CD034E7" modified="2010-04-20" version="1">MSTFPARAAQLDAITGAWAKLDGAPRTVVLTGPAGAGKSRLAAEALGLLDPVPGAVILGHARAGAPSPYDWLATALAGRPLSGLPASREALAWLTQSSDAPRLRLEPTALLKVAVAVVRHLLGDDPGVVVVEDVHALDPASLALIAELSRGEQPVLLLVLSRPADAERFPKAAAKLLKGLSETGRSQLITVEPLSDADVPPGEAAWARYAHALGLTTEAAPAALRGAARLLADGDAAAARRLVDACLGGHDDPGDDDVRLVLARSLLHLGRIESAASAARRAEGEAAAGLAATLKTITELTAREKEVLSCLAAGMSNRQVAKSLGISVRTVTVHVSNLLRKTGTGSRTEAALWAVEHGLSQDGHGDHAALPAPFCVTLTFKRYFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBJ1</accession>
    <name>D3QBJ1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3203</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3203"/>
    <dbReference type="EnsemblBacteria" id="ADD42873">
        <property type="protein sequence ID" value="ADD42873"/>
        <property type="gene ID" value="Snas_3203"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3203"/>
    <dbReference type="eggNOG" id="COG2271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_59_9_11"/>
    <dbReference type="OMA" id="WVLASHQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="405" mass="42426" checksum="C0F4901BE9CF31B1" modified="2010-04-20" version="1">MAAVAFVAIIGAAGMRATPGILIDPLHRAFGWSRGTISLAVTINLILYGLTSPFAAALMDRFGMRRVVASALGLVALGSGLTLFMRSSWELIIYWGLLVGLGTGAMAMAFAGTVTTRWFATRRGLVTGILTAAGATGQLIFLPLLAILVENYHWQAASATVAGCALAVVPLVWWLLRDRPEDVGLRPYGATGPTPAPVASGNAVARTFTVLARAAKTRTFWLLAGGFAICGASTNGLVSTHFVPAAHDHGMPTTMAASLLAVIGLFDIAGTVASGWLTDRFDPRKLLGIYYGLRGLSLLFLPMLLDDSLKPPILFFVIFYGLDWIATVPPTLGLCRTHFGDADAPLVFGWVLASHQIGAGAIAVTAGLIRDHHGTYTPAWLIAGGLCAAAAVMSLAITKPTATQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBN1</accession>
    <name>D3QBN1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3243</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3243"/>
    <dbReference type="EnsemblBacteria" id="ADD42913">
        <property type="protein sequence ID" value="ADD42913"/>
        <property type="gene ID" value="Snas_3243"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3243"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033532_1_1_11"/>
    <dbReference type="OMA" id="MPTWLLL"/>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="260"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="388" mass="38939" checksum="739AF4503AC777B3" modified="2010-04-20" version="1">MTPLLGIALLGRAAITADAIALTMYVVLALDLSYAAAGVVVAVLTAGVAVGGPVLGRMIDRRGLRAVLLATIGAQLLFWLSVPILSYVVLLPATLAAGLLMIPVQPVTRQAIAAMTTAEQRRAAFALESVMGELSYIVGPAVVIVFAAQASAGTAAWGLGAAIVAGGVGLMLLNPPLRSAHEAAASPAARPTRREWLGAPMIAVLVMAFGITMLLGGIDLAIVATLEHAGQVSWAALVIGVLGAASVVGGLVYGALPRPMPTWLLLGLLGLLTIPAGLARDWPWLCVAVLGAGLLTAPTLSTVADAVSRLAPASVRGEATGLQSSALSTGFALGAPIVGVAIDAISPAAGFATAGLAGLIAALVGRVLMRRSTLTPRPSEPDQARAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBR7</accession>
    <name>D3QBR7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine N-alpha-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.44</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Histidine trimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">egtD</name>
        <name evidence="5" type="ordered locus">Snas_5171</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-histidine + 3 S-adenosyl-L-methionine = 3 H(+) + hercynine + 3 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:38471"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15781"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; ergothioneine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyltransferase superfamily. EgtD family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.44" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020377.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5171"/>
    <dbReference type="EnsemblBacteria" id="ADD44806">
        <property type="protein sequence ID" value="ADD44806"/>
        <property type="gene ID" value="Snas_5171"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5171"/>
    <dbReference type="eggNOG" id="COG4301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049766_1_0_11"/>
    <dbReference type="OMA" id="RVEMHLV"/>
    <dbReference type="OrthoDB" id="775492at2"/>
    <dbReference type="UniPathway" id="UPA01014"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030745">
        <property type="term" value="F:dimethylhistidine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052699">
        <property type="term" value="P:ergothioneine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02037">
        <property type="entry name" value="EgtD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035094">
        <property type="entry name" value="EgtD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032888">
        <property type="entry name" value="EgtD_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017804">
        <property type="entry name" value="MeTrfase_EgtD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018005">
        <property type="entry name" value="UCP018005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03438">
        <property type="entry name" value="egtD_ergothio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_33" evidence="4">
        <location>
            <begin position="15"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="3">
        <location>
            <begin position="138"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-histidine binding" evidence="3">
        <location>
            <begin position="279"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="319" mass="34279" checksum="E1B72B5BE4ADA446" modified="2010-04-20" version="1">MLESHISEGDLDAALRADVVAGLTATPKRLPPKWFYDAHGSDLFEEITRLPEYYPTRAEAAALESGADRVAERTGATSLVELGSGSSRKTLLLIDALRRKGTLDSFVGFDVSSDALAAATAALSLRYPELSVSGIVGDFTEHLRHLPSGTSRLVAFLGGTIGNLLPAARADFLASLRTQLAPGEWLLLGTDLVKDPATLVAAYDDAAGVTARFNRNVLTVLNRRLDANFDVEAFTHVALWDAEAEWIEMRLRADRPMRVELPAVGLSVDFAAGEELRTEISAKFHLSGLAAELGTAGFAVSDWWTDPKGRFGLSLAEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTY5</accession>
    <name>D3PTY5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015314.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD39743">
        <property type="protein sequence ID" value="ADD39743"/>
        <property type="gene ID" value="Snas_0021"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0021"/>
    <dbReference type="HOGENOM" id="CLU_1081459_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049457" evidence="2">
        <location>
            <begin position="29"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="257" mass="24483" checksum="FF5FA94EA0A59835" modified="2010-04-20" version="1">MNKWLQRTVGTASIACGIALAASGIAQANQPIEIGDPLGSVSSLSSVADPGSVTGLAGGVPTDGLPAGGLPTDNPVGMVPDATQLTGQVGGVTKDLPGKKVVGSVSKLGKTGTQAADTAAPKTEGLPVGDGVPVVGGVTHGGLPVVGGNPITGGSAGQDLVNGVPVVGNMVGSAMNPNTVPAAAAKPAKAEKFGMGSDLVGSTMLGKGAVGGLHGDVTRPAEDLPLVGQLPVVDGLTQGGLPGATPLGADAPAPKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUC6</accession>
    <name>D3PUC6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_3269</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3269"/>
    <dbReference type="EnsemblBacteria" id="ADD42939">
        <property type="protein sequence ID" value="ADD42939"/>
        <property type="gene ID" value="Snas_3269"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3269"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_9_11"/>
    <dbReference type="OMA" id="GAYLEGQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="29"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="345"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="378"/>
            <end position="385"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD42939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="588" mass="62992" checksum="218FC8194972A074" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUE6</accession>
    <name>D3PUE6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction protein with EFhand domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3291"/>
    <dbReference type="EnsemblBacteria" id="ADD42959">
        <property type="protein sequence ID" value="ADD42959"/>
        <property type="gene ID" value="Snas_3291"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3291"/>
    <dbReference type="eggNOG" id="COG5126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096804_2_0_11"/>
    <dbReference type="OMA" id="EQFNHIA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="11"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="62"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="104"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="187" mass="20134" checksum="09EAFE7D48595DCE" modified="2010-04-20" version="1">MTVTSSQIPDLQRRKLERRFTLIDTNGDGAIRHDDCVRMMERLCAAFGETLESPKGGALAAAYDRMFATLIAELDNDADGAISRDEFVTGMFTVVGDPAGFDATLRGAAEAVMSLADTDGNGTLGPAEYARLVGAFGVGSDEAAEAFARLDRDGNGQLQLREIIEAEKEFFTSTDPDAPGNYFFGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUQ3</accession>
    <name>D3PUQ3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020498.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5293"/>
    <dbReference type="EnsemblBacteria" id="ADD44927">
        <property type="protein sequence ID" value="ADD44927"/>
        <property type="gene ID" value="Snas_5293"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5293"/>
    <dbReference type="eggNOG" id="COG2813">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056435_0_0_11"/>
    <dbReference type="OMA" id="ICAHYLH"/>
    <dbReference type="OrthoDB" id="2049098at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="48"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="214" mass="23356" checksum="0A18B902F1491B1C" modified="2010-04-20" version="1">MHTHDSTEQPPSPEAFWEERYRSRDRVWSGRPNPVLVDTVADVEPGTVLDLGCGEGGDAVWLASKGWRVTSVDISGTAIARTLDNAKAAGVGDRVRGERHDLAETFPDGAFDLISAQFLQSPLEFPRELVLRRAAHALNPGGLLLIVDHGAAPPWSDHKDHYFPSATEVHEGLDLDPDEWRAERVGSAERDATGPDGQTGVLIDNVIAIRRRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUT2</accession>
    <name>D3PUT2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fatty acid alpha hydroxylase, cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020527.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5322"/>
    <dbReference type="EnsemblBacteria" id="ADD44956">
        <property type="protein sequence ID" value="ADD44956"/>
        <property type="gene ID" value="Snas_5322"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5322"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037319_0_0_11"/>
    <dbReference type="OMA" id="GPRHWRA"/>
    <dbReference type="OrthoDB" id="520970at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="437" mass="49654" checksum="D678A3C19ABBE445" modified="2010-04-20" version="1">MTDHTRHVHPTPTDADAIPRVSGDQTLGLLRHGYGYLSGRMRELGADAFEGRMFGSRTVFMAGHDAARLFYDDDKLKRAGAVPSLIRLTLFGKRTVHALDDSEHQHRKAMFNRITAPARVAELADLTDRLWREAIADWTRRSQVRLFRESVRVLGTAVCRWAGIPTRDRELEPHLRDLAAMVDNFGAVGFGQLRGRLARRRANRWAANYIEAVRGELLRPGEKTALHVIAHHRDGDGHLLDTRTAAEELINVLRPTVAVSWFVCFAAHASHTHPQWRHRLASSDDDTVRAFVDEVRRFYPFAPLLAAKARRDFSWRGHEFPSGRWVILDLYGTDHDPDRWRDPDAFDPHRFLESPPDAYDFVPHGGGDSQTGHRCPGEDLTAVLLTRTVRRLAEIDYHVPTQDLGYSANRFPSRIRSGFVMTNVVKPRDALTPPETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV11</accession>
    <name>D3PV11_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">P22_AR_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5403</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45035">
        <property type="protein sequence ID" value="ADD45035"/>
        <property type="gene ID" value="Snas_5403"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5403"/>
    <dbReference type="eggNOG" id="COG3645">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096376_0_0_11"/>
    <dbReference type="OMA" id="PRHICEV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018875">
        <property type="entry name" value="Antirepressor_Ant_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10547">
        <property type="entry name" value="P22_AR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01994">
        <property type="entry name" value="ANTIREPRESSR"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="P22_AR_N" evidence="2">
        <location>
            <begin position="20"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="273" mass="30849" checksum="0D856556D4AC4089" modified="2010-04-20" version="1">MSYDAPGPYQPRNNPHEIVHIPFHGRVIHTALSADGEPVVILKPTVEEIGLDFSAQLEKLKTRSWAVVTETLISGADGKIYPMVSVNLETWSMLLANVDENKVILAARPIVIAYQRESAKALRDYWTRGVAANPRYSPREKAEMLAALKGIVDSGFLEAKGRQLVGRTLGEVPEFDEQTKPLTVAMYLNSLGLKSSAIRRVQSQFGKQLKARYRDQYGCEPPQMEDLVNRHMIKVAQYQEQHRPLFDAVWRSMNRDDGGTTRPKNRPDKNRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV27</accession>
    <name>D3PV27_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Erythromycin esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1373</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1373"/>
    <dbReference type="EnsemblBacteria" id="ADD41080">
        <property type="protein sequence ID" value="ADD41080"/>
        <property type="gene ID" value="Snas_1373"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1373"/>
    <dbReference type="eggNOG" id="COG2312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026490_2_1_11"/>
    <dbReference type="OMA" id="GFWTWRT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14728">
        <property type="entry name" value="Ere-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007815">
        <property type="entry name" value="Emycin_Estase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05139">
        <property type="entry name" value="Erythro_esteras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="303" mass="33755" checksum="0D0DF84782370A78" modified="2010-04-20" version="1">MKAILANAFIAVRVTEMVDIVEWIRSHNRDHADDPVRLFGLEPAAVRLSDYDDVIEQVRLAAPALADAVATRYEVIRTAHRTPEHVQIARGMHPGTPFAELGRAAYDLIAALDGFPALDTARRIAEHHEHTVAAGFDFDEQFRRVAQGIIDWHQSTGHKILFWEGLAHVANAEAMGFKGFSDQSGFTHTTGYRLRKHFGDGYVTLTVGFDHGTIHAGTQVPMPPSDFVDAVLGSAEPERYLLDLRAPRPEAVTRWLSGPHKLRIIAGIYKPEEDADNYVSGGPLDEWFDAVIRIREISPTTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV93</accession>
    <name>D3PV93_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Potassium-transporting ATPase potassium-binding subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP phosphohydrolase [potassium-transporting] A chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Potassium-binding and translocating subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Potassium-translocating ATPase A chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">kdpA</name>
        <name evidence="10" type="ordered locus">Snas_1440</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the KdpA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016717.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1440"/>
    <dbReference type="EnsemblBacteria" id="ADD41146">
        <property type="protein sequence ID" value="ADD41146"/>
        <property type="gene ID" value="Snas_1440"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1440"/>
    <dbReference type="eggNOG" id="COG2060">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018614_3_0_11"/>
    <dbReference type="OMA" id="RQGWAIL"/>
    <dbReference type="OrthoDB" id="296671at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00275">
        <property type="entry name" value="KdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004623">
        <property type="entry name" value="KdpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30607">
        <property type="entry name" value="PTHR30607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03814">
        <property type="entry name" value="KdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001294">
        <property type="entry name" value="K_ATPaseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00680">
        <property type="entry name" value="kdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0630">Potassium</keyword>
    <keyword evidence="3 9" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="522"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD41146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="553" mass="58010" checksum="6877F723916AE218" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV95</accession>
    <name>D3PV95_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1442</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016719.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1442"/>
    <dbReference type="EnsemblBacteria" id="ADD41148">
        <property type="protein sequence ID" value="ADD41148"/>
        <property type="gene ID" value="Snas_1442"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1442"/>
    <dbReference type="eggNOG" id="COG2223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046685_5_0_11"/>
    <dbReference type="OMA" id="VELFWGF"/>
    <dbReference type="OrthoDB" id="1345431at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="437" mass="44532" checksum="D1D209E8E87B0D47" modified="2010-04-20" version="1">MHTLDATALRRRYFLITLLTWLPLGMGAAGLVLLVTERGFDLATVGVLFLVQGLVVSGLELPTGGLADVIGRRGVLIASAVVGLVAMLWTAVATGWWELVLVAVLRGVSRALSSGPAEAWYVDSVHALSPDADIRRGLGLGNTATSIGLAVGTLAGGFIPLAVPLPDDGLVIPLSIPMFIGAALFALLLLVVGFGMPEPARTGARPRLGEVLRGVPATVTGGIRLGLRDRGLLRLLSLAVFAGMALNAVELLTPGRMETLAGSAEAGASVYGVVAMIGFAASGLGSSLSHTLTRLVGGRVRLAAVIGVLVSVLGLVVLFGTGAWSGTVGIVGACAGYAVMYVGIGLRMPVTSELIHRRVASGERATVVSIQSLLLQGGGSLATLGLPVLAAVWSVPGAWLVSGALLAVSALLYRRTRADRAAEDPARLSPAGMTTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVI0</accession>
    <name>D3PVI0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arsenical-resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3430</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018665.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3430"/>
    <dbReference type="EnsemblBacteria" id="ADD43094">
        <property type="protein sequence ID" value="ADD43094"/>
        <property type="gene ID" value="Snas_3430"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3430"/>
    <dbReference type="eggNOG" id="COG0798">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022869_0_0_11"/>
    <dbReference type="OMA" id="CTAMVLM"/>
    <dbReference type="OrthoDB" id="1493959at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015103">
        <property type="term" value="F:inorganic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="PTHR43057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="329"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR005508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="369" mass="39652" checksum="D783801215F185A3" modified="2010-04-20" version="1">MPVTTAPEATAETGSRSPVKLSMLDKLLPVWIGLAMVAGLLLGRTIPAFGPALDAMSIGGISVPIALGLLIMMYPVLAKVRYDRLDTVTSDRRLLASSLVLNWLLGPAIMFALAWTFLPDLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAAAVLVALNSVFQVLAFGLLGWFYLDLLPGWLGLTQSGLDVSVWTIVVNVLLFLGIPLAAGFLTRKLGERAKGRTWYEDRFLPKIGPIALYGLLFTIVILFALQGDAIIGQPLDVARIALPLLVYFALMWAGSFALGKTIGMGYERTTTLAFTAAGNNFELAIAVAIATFGVTSGQALAGVVGPLIEVPVLVALVYVSLWARRFFTAKQLSSRQATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVV2</accession>
    <name>D3PVV2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5441</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5441"/>
    <dbReference type="EnsemblBacteria" id="ADD45073">
        <property type="protein sequence ID" value="ADD45073"/>
        <property type="gene ID" value="Snas_5441"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5441"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_739419_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="13"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="374" mass="41819" checksum="BC0C41375AA1DF79" modified="2010-04-20" version="1">MPIVGDYLQRPTYEVLHTIGEGNVGICRLARHDIFDCNVVQKTISLLGIPDGVAREPHLLKEAQHKYLIKVWDAQWEPSPQFKGMEAVTFICDYYPGKSVYDALMDLHVFGLAGAMRICGQMLDALAYLHGDRAYVHRDIKPANILLDESRENAVLADLGSAGKIDPHGGTAPNYGGTPLYLAPEVHARNQVTAKSDLYAIGMVTIEMLAGRFPYEDIARSKVDARLASGKPALPDRYFVLPPYVPPNVKSFIRSLIRVDPSKRPATARAALQKLNGLRYVDWRRTLGTGLVGEWIGSWPPDKVPEKRRIYRVQSSTVKRKGHVEQIKLTAAWRRPAGTWRKVSKLERYVDREDAKALSVFFRDVEDAAHAAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW27</accession>
    <name>D3PW27_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020719.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5517"/>
    <dbReference type="EnsemblBacteria" id="ADD45148">
        <property type="protein sequence ID" value="ADD45148"/>
        <property type="gene ID" value="Snas_5517"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5517"/>
    <dbReference type="eggNOG" id="ENOG502Z8CG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1000864_0_0_11"/>
    <dbReference type="OMA" id="DRWWLAP"/>
    <dbReference type="OrthoDB" id="1582133at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="270" mass="30600" checksum="4152B8B1AEBB6102" modified="2010-04-20" version="1">MTSTIETPGKARAAISKRHLRTDNWWLTPLLTFLGLAGFLIYATVRLFVDGYYWSPEQSYLAPFYSPCLATTCTEGSSHFLGQPFDLSALPSWVSPAMIILILPGGFRATCYYYRKSYYRSFWVSPPACAVPDGHKKYTGETRFPLIFQNVHRYFFYAAVLVGAVLTYDAGIAFFDQAGDFRVGVGTVILVLNAIAIWAYTLGCHSCRNIVGGRLTHFSKHPIRYWLWTQVSKLNKRHQFWAWVSMFSVVIADAYVWMVSAGVFTDLTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW95</accession>
    <name>D3PW95_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1549</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1549"/>
    <dbReference type="EnsemblBacteria" id="ADD41252">
        <property type="protein sequence ID" value="ADD41252"/>
        <property type="gene ID" value="Snas_1549"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1549"/>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_3_11"/>
    <dbReference type="OMA" id="LEHTGMV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="9"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="25197" checksum="B92C0E4E30817C45" modified="2010-04-20" version="1">MAEAQVARQPLADQMYEVLLDRFMNGVHAAGEPLNIGALSRELNVSQTPLREALARLEHTGLVRREAMKGYRVSPSMTKSEIGKLMDARVVLESAMTYETALRTTPEFLDELRQTVEDLAQSAERADTETEYFRRYWSSDDRFHALIAERCDNPFLEAAYRALGGQIQRFRLFSKLGHTGAQFAAREHRAVYEALADRDPERAAELMREHIESAKNRNLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWE2</accession>
    <name>D3PWE2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1596</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016870.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1596"/>
    <dbReference type="EnsemblBacteria" id="ADD41299">
        <property type="protein sequence ID" value="ADD41299"/>
        <property type="gene ID" value="Snas_1596"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1596"/>
    <dbReference type="eggNOG" id="COG0553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009519_0_0_11"/>
    <dbReference type="OMA" id="RYERVCF"/>
    <dbReference type="OrthoDB" id="291634at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024975">
        <property type="entry name" value="NOV_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13020">
        <property type="entry name" value="DUF3883"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="114"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="479"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1137" mass="127515" checksum="4AB22D805C5520E3" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWE6</accession>
    <name>D3PWE6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016874.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1600"/>
    <dbReference type="EnsemblBacteria" id="ADD41303">
        <property type="protein sequence ID" value="ADD41303"/>
        <property type="gene ID" value="Snas_1600"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1600"/>
    <dbReference type="eggNOG" id="ENOG5031Z3V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1219106_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="227" mass="24164" checksum="19E011193C216EAF" modified="2010-04-20" version="1">MSTDNLMETYRLACERYTKAVVSATRTRDEAADRYRREAAEVKETAQQAVAERDTAMRDAVAAKKLVTEVDDTCADIWRRLGSYIGPKYTVITPPPGTAEDVSGVTDVKAMVERTRRTIALVQRGEVPFEPPKRAVPVAAVIGVVIGVLAAIGAGMLLSDSKDGHTQALSQAGALVVVFIGAFAGIPVLSGWLATRHRIGPRPIHIGACIVGAVVAMCAMAPFTFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWJ5</accession>
    <name>D3PWJ5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3555"/>
    <dbReference type="EnsemblBacteria" id="ADD43217">
        <property type="protein sequence ID" value="ADD43217"/>
        <property type="gene ID" value="Snas_3555"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3555"/>
    <dbReference type="eggNOG" id="ENOG50348RK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068054_0_0_11"/>
    <dbReference type="OrthoDB" id="2061312at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="341" mass="37235" checksum="B31EB9DF24D09B1F" modified="2010-04-20" version="1">MLERRFRRLLRVYPAWYRRVRGEEMLTTLMDAAQGRHRPSASERLDVVFGGMRKQLSSGSVSAAVAGVFVALFVATLGAIGGAVAGWHTAADLPDDAAADRIARQTIPDMDDVKTYKDRSLFGWVEEHGDLYDTRYITNRENDEFAGHMVYQMEHKANDYARLHGVKERLEAAGWNVRLVRKDSTSVEFTATRDGIDLWGYTSHGPSHPRISTIDITRATPTPVPVLTVTGLIIGALLGWTVTNRLARRISHGPTGRRVVTSALLGIGSCLLALPTAINVYFVAASLALPREPVPIWLAYTTAPESQVALLGTAALALALLCAALPIPTHRLTQSNPTTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWT7</accession>
    <name>D3PWT7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3651"/>
    <dbReference type="EnsemblBacteria" id="ADD43309">
        <property type="protein sequence ID" value="ADD43309"/>
        <property type="gene ID" value="Snas_3651"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3651"/>
    <dbReference type="eggNOG" id="ENOG50336G7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145448_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039470">
        <property type="entry name" value="Nuc_deoxyri_tr2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15891">
        <property type="entry name" value="Nuc_deoxyri_tr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="180" mass="20252" checksum="46E98D3765C7EF86" modified="2010-04-20" version="1">MVVRYVEAPHQADQRGDSFRWPAVFLGGGITGVDDWQASAVGMLEASGVDVTVYNPRRANFDVTDPAAHEQQVRWEYRHLHIADIVMFWFPACDPAVTVQPIALAELYAAMERRHQYRLIGAAPGYPRRRDIALQLRSAQTANHVPNSVVLQSSLRHTVNLVVEVIRSHPYQTPRAEFPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWZ9</accession>
    <name>D3PWZ9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5593</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020794.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5593"/>
    <dbReference type="EnsemblBacteria" id="ADD45223">
        <property type="protein sequence ID" value="ADD45223"/>
        <property type="gene ID" value="Snas_5593"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5593"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_4_1_11"/>
    <dbReference type="OMA" id="YTNTNYH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048433" evidence="2">
        <location>
            <begin position="23"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="444"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="3">
        <location>
            <begin position="33"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="480" mass="51498" checksum="AAC667167DF5E2B7" modified="2010-04-20" version="1">MKRIVIAVAAAALLVTPGVAAAKPHSGLDERSVDAFVGEYLENAGVKGVTVAVTKGTDVVVAKGYGTDSTGAELTGEAPMPIASLSKSFTALAVMRLSEQGKVDLDAPVREYLSEFTMDDPRAKRITVRQLLNQTSGMSDGTFSEKVEAQPSDLAGSVSRLADAELATAPGKSWNYHNPNFHVAARLVEKVSGEPFGEYLDTEVFAPLGMTKTSTVDVTDDAKLPRGHFAAYGQRAAAEPHRFVNGSDGIISTAEDMANWLAVNNGDGGELVSAKGFAELHEPSDPRGRYALGWNVGKRDGATVLDHGGVWFTYTARQLVIPETGYGFAVMANTGMSMAADVPYDLTEGLMALSEGDQPSTTDSPQSTNDLVLGLLTLAAIGWAAWRWYRSGVWARRRVDRPLWRNVLAGSRALFPALVLLSYPWLAGLVAAGRTATWTEHLYVWFPMLVWLSIATLGGLLVTGVRAVRLVRLRRSRATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX38</accession>
    <name>D3PX38_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5632</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020833.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5632"/>
    <dbReference type="EnsemblBacteria" id="ADD45262">
        <property type="protein sequence ID" value="ADD45262"/>
        <property type="gene ID" value="Snas_5632"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5632"/>
    <dbReference type="eggNOG" id="ENOG5032R9R">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174618_0_0_11"/>
    <dbReference type="OMA" id="LEGIDYW"/>
    <dbReference type="OrthoDB" id="1812905at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="102" mass="11745" checksum="68A029CC6F0EA444" modified="2010-04-20" version="1">MTGKLSHGTSGALRRFAGWVARGSVGNPLLEDIDYWDELRESPSQMESLFAVFANVLELDDDGEPVNEKYAERRAALWIYRYFTGTWPEGERPLEDWEAKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX70</accession>
    <name>D3PX70_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016904.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1630"/>
    <dbReference type="EnsemblBacteria" id="ADD41333">
        <property type="protein sequence ID" value="ADD41333"/>
        <property type="gene ID" value="Snas_1630"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1630"/>
    <dbReference type="HOGENOM" id="CLU_129331_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048049" evidence="2">
        <location>
            <begin position="23"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="17977" checksum="03C015F18765BB2A" modified="2010-04-20" version="1">MTRILRVCVAALGLAAVLGATACDDKPDDKASESASASASESPSDKEEKTTESAPEPDSKEAGIARFEEYMHSVGSGDAKGACEMAAKMFASQKECVSAYGFMFAQMPDNEAKALTKATVDASQVEESKPGELFIPESAIELGITFSEPFGDYPLYFEDGSWYIRDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXW4</accession>
    <name>D3PXW4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron-containing alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5663</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020864.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5663"/>
    <dbReference type="EnsemblBacteria" id="ADD45293">
        <property type="protein sequence ID" value="ADD45293"/>
        <property type="gene ID" value="Snas_5663"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5663"/>
    <dbReference type="eggNOG" id="COG1454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007207_0_0_11"/>
    <dbReference type="OMA" id="FHVAHGE"/>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08182">
        <property type="entry name" value="HEPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035873">
        <property type="entry name" value="PhpC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="8"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="386" mass="40602" checksum="EC65D250050B761C" modified="2010-04-20" version="1">MTLPDDRDVRFGDDAILDTWQLVSKLDGKRAVLICGQHAFDASGANRCLDELTKVAEVRRWSEFHPNTDAADLIHGLRVVEEFKPDLVLGVGGGSAMDMAKLLCAYQGITDAEQLHAAIRTGAAITERRLKLVLAPTTSGSGSEATHFAVVYIGNDKYSIAGPAMLPDTVILDPKLTLTASPYQRATSGIDALAQATESLWASGASDASRGFARAAIDLLVPALPEFVNNPSSEVAGRMAQGSHLAGRAIDVSKTTAAHALSYGFTKSYGVSHGHAVALTLGAFIEAHAKATPDNLQPSVDPATHAEGMRTLLAAFGAADAADARARFDAIAEECGLPLKLAEHGITTREQVADLASRVNVERLGNNPVVFTKEQLTELVAAGLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXW6</accession>
    <name>D3PXW6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoenolpyruvate mutase</fullName>
            <ecNumber evidence="2">5.4.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.4.2.9" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5665"/>
    <dbReference type="EnsemblBacteria" id="ADD45295">
        <property type="protein sequence ID" value="ADD45295"/>
        <property type="gene ID" value="Snas_5665"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5665"/>
    <dbReference type="eggNOG" id="COG0615">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027389_0_1_11"/>
    <dbReference type="OMA" id="IIHGDDW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050188">
        <property type="term" value="F:phosphoenolpyruvate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012698">
        <property type="entry name" value="PEnolPyrv_PMutase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02320">
        <property type="entry name" value="PEP_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="3">
        <location>
            <begin position="12"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="437" mass="48380" checksum="C6275CA2BBC00358" modified="2010-04-20" version="1">MSSKPTVYVGMSADLVHPGHINILQRAAELGDVTIGLLTDAAIASYKRLPHMTYEQRKAVVENIKGVAAVVPQETLDYVENLEKLKPNFVVHGDDWKTGVQQQTRQRVIDALAQWNGELVEVGYTEGISSTQLNESVKEVGTTPNVRLSRLRRLIENKPIVRIMESHSPLTGLIIETTTAEHNGRKVEFDGMWSSSLTDSTARGKPDIELVDPASRMQGINDLFDVTTKPLIYDGDTGGKPEHFSYTVRSLERLGVSAIIIEDKEGLKRNSLFGTGAQQTQCSIEDMVHKIQVGKKAQVTKDFMVIARIESLILEQGMDDAVKRARAYIDEGGVDGIMIHSRQKTPDEVFEFCELFQKFPKRVPLVVVPTSYNTVVEDEFAKRGVNVVIYANQLMRASYKAMASVATSILENGRSAEVDSQIANIKEALAIIPENLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY34</accession>
    <name>D3PY34_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020934.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5733"/>
    <dbReference type="EnsemblBacteria" id="ADD45363">
        <property type="protein sequence ID" value="ADD45363"/>
        <property type="gene ID" value="Snas_5733"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5733"/>
    <dbReference type="eggNOG" id="ENOG502ZTWD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190776_0_0_11"/>
    <dbReference type="OMA" id="TEAVWHH"/>
    <dbReference type="OrthoDB" id="2084627at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="82" mass="8817" checksum="E5ABCEA4A332F4AA" modified="2010-04-20" version="1">MATDHPDRDGWQSTRWVIGLVLFVQGFGSAITESLWHTSFGAAALLRSAGLPQWTDLLVGAVGVGLLVWAAARARSRRKANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYB9</accession>
    <name>D3PYB9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Necrosis inducing</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1789</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1789"/>
    <dbReference type="EnsemblBacteria" id="ADD41486">
        <property type="protein sequence ID" value="ADD41486"/>
        <property type="gene ID" value="Snas_1789"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1789"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_398967_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="PTHR33657"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="17"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="690" mass="72032" checksum="5E7E6BA960CC2A7C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYE9</accession>
    <name>D3PYE9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Formate--tetrahydrofolate ligase</fullName>
            <ecNumber evidence="6">6.3.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Formyltetrahydrofolate synthetase</fullName>
            <shortName evidence="6">FHS</shortName>
            <shortName evidence="6">FTHFS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fhs</name>
        <name evidence="7" type="ordered locus">Snas_1820</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6S)-10-formyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20221"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.3" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1820"/>
    <dbReference type="EnsemblBacteria" id="ADD41516">
        <property type="protein sequence ID" value="ADD41516"/>
        <property type="gene ID" value="Snas_1820"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1820"/>
    <dbReference type="eggNOG" id="COG2759">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003601_3_3_11"/>
    <dbReference type="OMA" id="CGEIMTM"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00722">
        <property type="entry name" value="FTHFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="67"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="565" mass="59000" checksum="6208E8A5D22B69F9" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ08</accession>
    <name>D3PZ08_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane-bound metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5807"/>
    <dbReference type="EnsemblBacteria" id="ADD45437">
        <property type="protein sequence ID" value="ADD45437"/>
        <property type="gene ID" value="Snas_5807"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5807"/>
    <dbReference type="eggNOG" id="COG1988">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071993_0_0_11"/>
    <dbReference type="OMA" id="PGQEYLW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007404">
        <property type="entry name" value="YdjM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04307">
        <property type="entry name" value="YdjM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="277" mass="29200" checksum="A3D9B9AEEA5F3BEC" modified="2010-04-20" version="1">MVMGPTHAVSGAAAWLVASAVAETAFNFHQGPTTLALGTVACTGAALLPDLDCSGRVLKNKGGATVARTFGVASLFLAECVEKFSLGVYKITRSKKDGKKSNGHRTFTHTWLFAALLGVGVGALAYNFGRPAVAAMMFLLTGLAIRGVMNDWAKKQGWWIITLISLAVAVGLHQELPDHRPYVVLGAAVGIGCVVHTFGDMITKMGCPVLFPVPIQKRRWKDIGVPDKIAIRAGSKVEEKVLMPLFVTIAVAALLFTSAEVRGTVGGWMVAAGNLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ43</accession>
    <name>D3PZ43_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5843</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45472">
        <property type="protein sequence ID" value="ADD45472"/>
        <property type="gene ID" value="Snas_5843"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5843"/>
    <dbReference type="HOGENOM" id="CLU_1383430_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="197" mass="20754" checksum="A7F19C130CB1A8C8" modified="2010-04-20" version="1">MYEDNAWPDTAPIQTFIPERKRPQRVFIAGMATLTAAGAALLAGLLHLAVAETRGGSFLVDIPGVVMVVLGLAVAAWLGLVAQAVLKGRKWIPKPAMYSGGGLLVFFGLIGLLAKPGPAVGDGAFGLWLYAILAFLAAVAGVTTAVCLLGRNVAEYFDPPAQPSPFQQNNNQAPMGGYDSDWIPPQQRGRPQPPFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ62</accession>
    <name>D3PZ62_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021062.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5862"/>
    <dbReference type="EnsemblBacteria" id="ADD45491">
        <property type="protein sequence ID" value="ADD45491"/>
        <property type="gene ID" value="Snas_5862"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5862"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_5_11"/>
    <dbReference type="OMA" id="HRFPRID"/>
    <dbReference type="OrthoDB" id="1377545at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="288" mass="30862" checksum="300BAC24F45E131F" modified="2010-04-20" version="1">MDGKTVLITGSTGGIGKETARGLATLGATTFLLGRDPTRAEAAARELRADTGNPRITALTADVSRPTDLRRLATELADRVERLDVLVNNAGTSRPRREVTADGVEAMFATNVLAPFMLGGELLPLLRGGGRIVNLTGGIPKGRIDPGNLLAERKFVGFTFSQYNHTKLAVMAMSLGFADRVAEHGVTVNVAYPGHASTPGNRDLPMSAFPVVYRPAAPLLRWFGPRLLGGDAVAKASRSSVYLASSPEVEGVTGAYFDKHCRRAKWPPSVLDQANQDTVWRLCERLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ75</accession>
    <name>D3PZ75_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vesicular transport-associated repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021075.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5876"/>
    <dbReference type="EnsemblBacteria" id="ADD45504">
        <property type="protein sequence ID" value="ADD45504"/>
        <property type="gene ID" value="Snas_5876"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5876"/>
    <dbReference type="eggNOG" id="COG3599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017257_1_0_11"/>
    <dbReference type="OMA" id="IYEHARI"/>
    <dbReference type="OrthoDB" id="937807at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="404" mass="44630" checksum="9E97524432A307DF" modified="2010-04-20" version="1">MRGYDRGQVETYARRMSAAVKNAEASRTEAETKLSEVRTSLRRTEDRLGSLERRMADTAAQIAENEQPTLAGLGARVEKDLRASERDADEQREEARRQALAIREDAKAEAARTSEVARAEATAVTTSARREAEELAAAARTESTEVRESARRDVELLRADTIRDVEQKRASASQEAAELKASAEREIAVNRATVDRESTQLRAAAARDSDEQRAAAATLLAEAAETRQSKLQELSLAEAERREQAEREHSKRHSDAVTQAQRIVAEAEQRWALADQRARETRQKAEDRESEADRKSEELAAQTEAAVAQILSEARAEADRLRTEAETAAEEMLKPLRDEVAELKRRELSVSSNLDDLRRQLGTVAGEQAAAVLDNLAVNASLPINAPRSGYEVETPTQQIPAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZB1</accession>
    <name>D3PZB1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chloramphenicol phosphotransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1889</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017156.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1889"/>
    <dbReference type="EnsemblBacteria" id="ADD41585">
        <property type="protein sequence ID" value="ADD41585"/>
        <property type="gene ID" value="Snas_1889"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1889"/>
    <dbReference type="eggNOG" id="COG3896">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101381_0_0_11"/>
    <dbReference type="OMA" id="MIILNGG"/>
    <dbReference type="OrthoDB" id="1869017at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012853">
        <property type="entry name" value="CPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007531">
        <property type="entry name" value="CPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="6"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR007531-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR007531-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="173" mass="18623" checksum="0120A831DC562160" modified="2010-04-20" version="1">MILLNGGSSSGKSSIARCLQDILPRPWLALSVDDFVDALPEAMRSSDEGIEFADDGAVNVGDQFRKLEVAWMAGVATMVREGAPVVMDDVFLGGADSQRRWREALDGLDVLWVGVRCDGAEAARRESARGDRTTGMAEQQAELVHRGVTYDLEVDSTHLSARECAEAIAAKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZS1</accession>
    <name>D3PZS1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43608">
        <property type="protein sequence ID" value="ADD43608"/>
        <property type="gene ID" value="Snas_3956"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3956"/>
    <dbReference type="HOGENOM" id="CLU_1748531_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="149" mass="15891" checksum="1D7CDABABE6F5DDD" modified="2010-04-20" version="1">MTPKTRAAVVTVETLTETVTVSLDGANPVPGILDIYPDPAASAFGLAIQWTITVNGTIGATFQVPPQHVQMRITYGKGQKAGGGGIIRAGSHQNGTTVIYGEGPLSGCLHERFDDVEFTAPGTGRVRRLRVCQSCDLFVDRTKIPIRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q007</accession>
    <name>D3Q007_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5908</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021107.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5908"/>
    <dbReference type="EnsemblBacteria" id="ADD45536">
        <property type="protein sequence ID" value="ADD45536"/>
        <property type="gene ID" value="Snas_5908"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5908"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_11"/>
    <dbReference type="OMA" id="YACDIRI"/>
    <dbReference type="OrthoDB" id="1498685at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="243" mass="26237" checksum="21924085982169F5" modified="2010-04-20" version="1">MSFSTLLVEERSDRLVVRLNRAAKRNAIDQDMVDELHAVCASLEDRPRLALFTGGADGIFAAGADIAQLRDRTSLDALRAINSALFRRIRALPLPTVAAIDGPALGGGAELAYACDIRVCTDRAVFGQPEVRLGIMAGAGATWRLPELVGESLAKELLFTGRRMDATEALGARLVSRVVAPEALFDTAHELLDQIAKASPLALRLTKLAVDAEGAHPAVDLAAQSLLFDDEDKHRRMTKFLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q026</accession>
    <name>D3Q026_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5927"/>
    <dbReference type="EnsemblBacteria" id="ADD45555">
        <property type="protein sequence ID" value="ADD45555"/>
        <property type="gene ID" value="Snas_5927"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5927"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_1_0_11"/>
    <dbReference type="OMA" id="IVSTNCW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="9"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="400" mass="43091" checksum="0742DE7E84846DD3" modified="2010-04-20" version="1">MDTTSTRGTVLVSGASIAGPAVAYWLRHYGFAVTVVEKAGAVRGGGYPIDVRGTALEVVRRMGILPELRRAHVESRRLTFVEGDGDTVASLDPQAVTGGVDGRDVEVRRGDLATVLYRAVAEDVEFVFDDSIDTLTEDAHGVDVTFRSGMKRGFDLVIGADGLHSRTRELVFGPEQRFHHYLGYCFAGFTMPNRSGLSHEGVIWNDPGRGAVQYAVRDSDELHGLLVFARPQPPYEAFRDPRAQQDLVAETFADVGWEVPDMVAAMRRADDLFFDVVSQIRQPRWSSGRVALVGDAASAPSFLTGQGSSLALVGAYMLAGSLATHRDHAAAFAAYERDTRGFVELNQAQIGEGGAALFPVTAEALAHRNQRLRGLANPPSRAASTGRPAHTALELPAFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0A7</accession>
    <name>D3Q0A7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phosphomannomutase</fullName>
            <ecNumber evidence="9">5.4.2.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_6010</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.8" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021207.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6010"/>
    <dbReference type="EnsemblBacteria" id="ADD45636">
        <property type="protein sequence ID" value="ADD45636"/>
        <property type="gene ID" value="Snas_6010"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6010"/>
    <dbReference type="eggNOG" id="COG1109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016950_9_2_11"/>
    <dbReference type="OMA" id="KCSQVMY"/>
    <dbReference type="OrthoDB" id="256504at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004615">
        <property type="term" value="F:phosphomannomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="6">
        <location>
            <begin position="8"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="7">
        <location>
            <begin position="156"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="8">
        <location>
            <begin position="262"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="5">
        <location>
            <begin position="375"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="454" mass="48020" checksum="47297E3E6B48CF7C" modified="2010-04-20" version="1">MPDLGGIVKAYDIRGLVPEQWDEDVAAAFGAAFVSVTGVDTVVIARDMRESGVGLSAAFARAAAAAGADVLDAGLCSTDELYYVSGSRDIAGAMFTASHNPAVYNGIKLCLPGARPISMDTGLAAIRDKAQAILDGHPAPAADKPGTVTAQDFLEGYAAHLRGLVDLSGIRDLNVVIDAGNGMAGHTVPAVLGPVDALSVVPMYFELDGNFPNHEANPLEPANLVDLQKAVVERGADLGLAFDGDADRCFVVDERGEPVSPSAITALVAEAELARHPGSTVIHNLITSRAVPEVITENGGKAVRTRVGHSFIKAEMAKADAVFGGEHSAHYYFRDFWFADTGMLAAMFVLRALGNASVPLSDLVASYDRYVSSGEINSTVADQSAKLSEVEEYYADRAGTSVDHLDGLTITFADGAWLNLRPSNTEPLLRLNAEAPTVERMRELRDEVLAQVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0E2</accession>
    <name>D3Q0E2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0084"/>
    <dbReference type="EnsemblBacteria" id="ADD39806">
        <property type="protein sequence ID" value="ADD39806"/>
        <property type="gene ID" value="Snas_0084"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0084"/>
    <dbReference type="eggNOG" id="COG1476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055817_1_3_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043917">
        <property type="entry name" value="DUF5753"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19054">
        <property type="entry name" value="DUF5753"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="33"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="290" mass="32380" checksum="A78202D876CB2600" modified="2010-04-20" version="1">MCGPPDSREEVLTMTNDPSARPTLARRQLGAELRKLREAAGMTHAEAGAAVELHRNTIAAIEKGKQGTKSYIVKNLCSPEVYDAPPEVMSYLTGLVVKGKQRGLYEKHEPGMKPGIRWFASAEVEYGYIMTWEHLNMPGLLQVPEYYDAQRQTRPPQEAPDEPATKNFRFKRQEVVFGRDPLPRMEFVIGEGALHVMDGLPDVKDAQIARLLEVAKLPGVDIRVLGGFHPAMSGAFTILSPTDPDDELSFVYVDALDACRYLEDPDVVSRFVGTFRTIYSMAIPIKEFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q193</accession>
    <name>D3Q193_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6049</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6049"/>
    <dbReference type="EnsemblBacteria" id="ADD45673">
        <property type="protein sequence ID" value="ADD45673"/>
        <property type="gene ID" value="Snas_6049"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6049"/>
    <dbReference type="HOGENOM" id="CLU_1947517_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="129" mass="14166" checksum="487A5BB71C8633FD" modified="2010-04-20" version="1">MTEVVVNRETMRRFYRWCQTEAANLTGWREDACLPEQDMTPDANTGRVHAGMPVPIPDGPGVGEAGGRFATQLVDSAVQHRAILEGLNALGAIAEQALSEMDNTDVISAERLGEITRDYLPEGWLPWAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1A9</accession>
    <name>D3Q1A9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_6065</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021260.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6065"/>
    <dbReference type="EnsemblBacteria" id="ADD45689">
        <property type="protein sequence ID" value="ADD45689"/>
        <property type="gene ID" value="Snas_6065"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6065"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_9_11"/>
    <dbReference type="OMA" id="RWVATIT"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="29"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="343"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="376"/>
            <end position="383"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD45689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="578" mass="61594" checksum="236C13B1044D84D3" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1B1</accession>
    <name>D3Q1B1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6067"/>
    <dbReference type="EnsemblBacteria" id="ADD45691">
        <property type="protein sequence ID" value="ADD45691"/>
        <property type="gene ID" value="Snas_6067"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6067"/>
    <dbReference type="HOGENOM" id="CLU_1420681_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="191" mass="20831" checksum="70CF053FE264CAE1" modified="2010-04-20" version="1">MRFFANDDHRHASAIWSWRNTTVVMSLALVTSLAVGIAAAGGLSVLDEPRGYGGAETLPPPQADPKPPALLPDDPGPPPAPNPAEPVETEEFRDNAPAAHDTFDTRQVEAETAPDAVDEVEQAGSGVWNQVEDTVDELPIEWPEPSTHVFTWENLDCPDGETEYFASSGGYDLPSWDTGYSDPWMYERLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2N5</accession>
    <name>D3Q2N5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CoA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021357.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6163"/>
    <dbReference type="EnsemblBacteria" id="ADD45786">
        <property type="protein sequence ID" value="ADD45786"/>
        <property type="gene ID" value="Snas_6163"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6163"/>
    <dbReference type="eggNOG" id="COG1042">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007415_2_3_11"/>
    <dbReference type="OMA" id="CVPPIFI"/>
    <dbReference type="OrthoDB" id="445933at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043758">
        <property type="term" value="F:acetate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043938">
        <property type="entry name" value="Ligase_CoA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032875">
        <property type="entry name" value="Succ_CoA_lig_flav_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19045">
        <property type="entry name" value="Ligase_CoA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13607">
        <property type="entry name" value="Succ_CoA_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA_binding" evidence="1">
        <location>
            <begin position="8"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="442" mass="44234" checksum="54A805E46FEC837F" modified="2010-04-20" version="1">MSSSISALWNARSIAVYGASDREGSAGGRVLDYLRAYGYTGRVIPVHPGADTVRGLQARPSLAGAEAELALLLVGAARIPAALDDCLDAGVTTVIVGASGFAETGAVAAQDALVARAAEAGARLLGPNCIGAANLHNGLIASFSPYFEAEPATPGGLALVSHSGGLGFGITSLAAERGLAPGRVVTTGNEADLSAGEVMCALAEEPDCTGVLAYLESTPDPKWLKQLHATGKPIAALYASATTASSTNAGGSEARVLPQFGIELADDVDELLDFASGFDTPPPAGPRLAIVTTSGGAGHLATKAVAGSGLKLPEPSAATLKTLTESLPPYATIGNPVDVTATVTSDPGLLSRTLATVAADDGFDAVLVCLCVLAGPQAEQAAAAVIDAASSSGKPILVSRTGSRELAPGFAARLAAAGIGVYPTPARAVAALCARRMTFRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q310</accession>
    <name>D3Q310_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemolysin-type calcium-binding region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015551.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0262"/>
    <dbReference type="EnsemblBacteria" id="ADD39980">
        <property type="protein sequence ID" value="ADD39980"/>
        <property type="gene ID" value="Snas_0262"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0262"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_457723_0_0_11"/>
    <dbReference type="OrthoDB" id="1560944at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028208">
        <property type="entry name" value="Effector_pro_NleD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14891">
        <property type="entry name" value="Peptidase_M91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="665"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="692"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="729" mass="77244" checksum="E5FDC76FDF8004F6" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q333</accession>
    <name>D3Q333_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015574.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0285"/>
    <dbReference type="EnsemblBacteria" id="ADD40003">
        <property type="protein sequence ID" value="ADD40003"/>
        <property type="gene ID" value="Snas_0285"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0285"/>
    <dbReference type="eggNOG" id="COG0006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017266_4_1_11"/>
    <dbReference type="OMA" id="IHEWPYL"/>
    <dbReference type="OrthoDB" id="415910at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="2">
        <location>
            <begin position="12"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="1">
        <location>
            <begin position="153"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="374" mass="39940" checksum="22A04425C3D4B1B1" modified="2010-04-20" version="1">MTIFTKVELTDRLAKARSATEASGIDAVLISPGADLHYLTGYDAKPLERLTCLVLRPGAEPLLVVPVLERAAAQASPAGDLGLELVSWHETEDPYALVAALLPPGTRRIAYDNHMWAEKLLAFRSALPGTEQELAGEILRELRMRKSGNEIEALRRAGAAIDRVHARMAEWLRPGRTEREVGADIAEAIAAEGHATVDFVIVGSGPNGASPHHDLSDRVIQPGDPVVVDIGGTTADGYCSDSTRTYVAGGEAPEEFAAYYEVLLRAQIAACEHVRPGVTAASVDAAARDVIAAAGYGERFIHRTGHGIGMQGHEDPYIVAGNERVLEPGMAFSIEPGIYVDGAHGARIEDIVVVTDDGVERLNLTPRELVVIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3C8</accession>
    <name>D3Q3C8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2280</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017540.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2280"/>
    <dbReference type="EnsemblBacteria" id="ADD41969">
        <property type="protein sequence ID" value="ADD41969"/>
        <property type="gene ID" value="Snas_2280"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2280"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_59_0_11"/>
    <dbReference type="OMA" id="MRLSLYD"/>
    <dbReference type="OrthoDB" id="1594866at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="6"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="405" mass="41877" checksum="02FC75BB6555DDA7" modified="2010-04-20" version="1">MSATETSAAVPTAQAIAGRRRGLVALCVTEITSWGILYYAFPVLLVAITADTGWSTTVVMGAFSVGLGVSALAGIPVGRLLDRYGPRPVMTVGSVVGVVAIAGIALAPNPWWFTAAWAVSGLAQACVFYKPAFAAITGWYGPDRVKALTTVTLVAGLSSTVFAPVAAFLVDRVDWRTTYLILGAFLAVVTIPVHARFLKVPWNPQHDQPGSRTTGNRAIMRSPAFLTLVLVMTTATFALFAATVNLVPMLTDRGASTSFAAWTLGLCGAGQLLGRIGYARLTARTSIRFRTVAVLVAAAVTIVLTAVTAHQAAALIAAAIAFGATRGIFTLLEATAVSDRWGTRNFGVLYGAYSAPSTIAMAAAPWAGALLVNALGGYQALFIAMAVLAAAAGVAATATIPRQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3K2</accession>
    <name>D3Q3K2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017614.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2357"/>
    <dbReference type="EnsemblBacteria" id="ADD42043">
        <property type="protein sequence ID" value="ADD42043"/>
        <property type="gene ID" value="Snas_2357"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2357"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4991">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058006_0_0_11"/>
    <dbReference type="OMA" id="CERNGSA"/>
    <dbReference type="OrthoDB" id="401539at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048212" evidence="1">
        <location>
            <begin position="31"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="182"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="402" mass="42969" checksum="02E143DA79A2CE07" modified="2010-04-20" version="1">MERFNLPKTIAAVIAAITITVVGGGSTAVAAPPNLKDTVAATLVAEKADEARDSYGVSTSANLSTLVETKRTSADGLWAFGGAVLKVPSSSHASPVTALFFAQRTMNGWEVALKGTEEFAEAARQAPDDILRDEGERDVLAATAKPRTALAPTGLALPWANGQGGWRHWGVHGNSGTSRPYNSIDFYGGDGQVRAAAGGYLYRYCGTSTPLIEIEHDNGWTTGYYHTWNQTTVADGTKVGAYAYIGRIGEQLPCGGRANGDHVHWTLWQGNTAVTVNNKEIGGWTWHEQSQAYRGWASRNGVNIYNSDCCLTNYGPGSGTTTGRAHNPDGVVNVRTEPKANATVLRTIAHDTEVELECYVRGDTMTGPWDNTSDVWDRLPGGGYVSDAWLDTGSDEPIVDPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3L6</accession>
    <name>D3Q3L6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2372"/>
    <dbReference type="EnsemblBacteria" id="ADD42057">
        <property type="protein sequence ID" value="ADD42057"/>
        <property type="gene ID" value="Snas_2372"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2372"/>
    <dbReference type="HOGENOM" id="CLU_997171_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="279" mass="28926" checksum="8322E2DD90E67A78" modified="2010-04-20" version="1">MFHTRLSLAHGSYNEGSGTALQCGGRAVSMGKSFSSCWLAVLGVVAVVGFGVAGCSSGGGKADSKKPEASGSPSTTKELDYAAIAEEALVSPDLEALSDYMLNGTNVVADPWGPCVEDAPQAVDERDRAQRTFQGKRMAMVTSTGLALAGSVDDAMGELRELWLSKECESFEGSRVGLPGSEEVFDYERVKKLKAPKGVDDDSWVGVCVDGRGKTAADSPTGQQLTGQCLVVYVSGKHSISEVSADFIPGLSAGVKVPSFTLAECAKTVTRVAAAAVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3U6</accession>
    <name>D3Q3U6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4366</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019584.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4366"/>
    <dbReference type="EnsemblBacteria" id="ADD44013">
        <property type="protein sequence ID" value="ADD44013"/>
        <property type="gene ID" value="Snas_4366"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4366"/>
    <dbReference type="eggNOG" id="COG1408">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037730_0_0_11"/>
    <dbReference type="OMA" id="DIHLNPA"/>
    <dbReference type="OrthoDB" id="764005at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049681" evidence="3">
        <location>
            <begin position="31"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="4">
        <location>
            <begin position="223"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="489" mass="51899" checksum="F4ACE38554D54C59" modified="2010-04-20" version="1">MRRTGKAIVFTAIALFAAGLGVRFLGTATADIGPFHTTMSMEPATDGESEVELPPLGSLIFNSHSGPIKMTVRIDSLDEFRTERLIDNPKEIRMVGQEVPADVRAGFTNAGLSGLGGATLAGLILGGLAFRTMRRAAICGSLSLVLTATALGISAGSMRPESVAEPRYEGLLVNAPAFVGGAQQVADSYEKYRSQLEGMIVNLSQFYTLGRTLPSFVEDKDTIRVLHVSDLHLNPSAWNVIDSVAKQFSANAVLDTGDITDWGSTQEAAVYTKGIKRLDTPYVYIRGNHDSTKVTKEVAKQKNATVVDDEVVEIAGLRIAGIGDPRYAPDATSAPSDIREEQVLLDSGNDLRDTIAESGGADLAMVHDPVCAGPLAEEVPVVLAGHKHQRLVSKLDDDTVQMVQGSTGGAGLSGIDKDNPHPLTLSVLYFDKSDARLKAVDDIAVGGTGETQVSLQRRIFSKGMPDDNTDLVPNPDEVEDGASGDPEGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3V9</accession>
    <name>D3Q3V9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4379"/>
    <dbReference type="EnsemblBacteria" id="ADD44026">
        <property type="protein sequence ID" value="ADD44026"/>
        <property type="gene ID" value="Snas_4379"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4379"/>
    <dbReference type="eggNOG" id="COG5282">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031872_1_1_11"/>
    <dbReference type="OMA" id="LFAHVPW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018766">
        <property type="entry name" value="Zinicin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042271">
        <property type="entry name" value="Zinicin_2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39420">
        <property type="entry name" value="PTHR39420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10103">
        <property type="entry name" value="Zincin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03624">
        <property type="entry name" value="TIGR03624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="414" mass="45061" checksum="55562AB431F97226" modified="2010-04-20" version="1">MPDPNDPRVQQMMAQLQHMMSQQSSGPVNWDLARQLANQQVGEDPMVDSRSRTAGDESLRLADLWLENATTLPSGTSTTVAWTRKDWIAHTVDTWKELAEPLAAHMADALQELVPEDMRAMLGPMSSLMKGLGSTLFGAQLGQAMASLSTQVMTSTEVGLPLGPAGTAALIPANLAEYAEGLEDIDIDEVRLYVSLRETAHHRLYGHVPWLRAHILGGVEAYSRGIHIDTSAIESLTGDLDFSDQEAMRNVDLGELLRTSDTPQQQAAVARLEHMLALVGGWVSHVAAQAAGDRLPSLSKLTESARRRRATGGPAERTFEALVGMKLSPKKLREATALWEKLTEERGVDGRDAVWSHPDLMPSPEDLDDPDAFAAREPGLGDLDMSIFDQLAVNDPKPPREDDDSDGDQGKNPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3X2</accession>
    <name>D3Q3X2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4392</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019610.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4392"/>
    <dbReference type="EnsemblBacteria" id="ADD44039">
        <property type="protein sequence ID" value="ADD44039"/>
        <property type="gene ID" value="Snas_4392"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4392"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1359706_0_0_11"/>
    <dbReference type="OrthoDB" id="1755232at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="201" mass="20273" checksum="BC5DAAB62FC05195" modified="2010-04-20" version="1">MRPEKPPRTGLHRWGGEKPALMVLGGVVGLALVLGLIVLVVSGDPEPTPDTASDTGSTSTTASASPSPSAKSPGAASSKSESKKYTPGKNPHGAKEVCGGGFKPIDKLTVKSGSTTLGTVNLLFNAGNGANCVVTLKAVDIGKKTPMTASLSLKSGKSGDESGSFGYYAGPVKREAARTCVKWSGSIDGVAVDSGDWSHCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q448</accession>
    <name>D3Q448_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6315"/>
    <dbReference type="EnsemblBacteria" id="ADD45933">
        <property type="protein sequence ID" value="ADD45933"/>
        <property type="gene ID" value="Snas_6315"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6315"/>
    <dbReference type="HOGENOM" id="CLU_3333262_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="38" mass="3942" checksum="C5287F94F39538AB" modified="2010-04-20" version="1">MSASPANRTVVRRGVHIGGSMPDPATRLRVSFDSGSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q452</accession>
    <name>D3Q452_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021508.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6319"/>
    <dbReference type="EnsemblBacteria" id="ADD45937">
        <property type="protein sequence ID" value="ADD45937"/>
        <property type="gene ID" value="Snas_6319"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6319"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_40_0_11"/>
    <dbReference type="OMA" id="AACIPDN"/>
    <dbReference type="OrthoDB" id="1501005at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="30"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="23225" checksum="549603437BCC9E55" modified="2010-04-20" version="1">MMNNPGWPATLVHDRVSLRPYQRSDATEWSAVRVRNEGWLAHWEPVSGVAWQESNSPSAFRLLLRDLRKSAKTGITWPFAICFDGKIVGGMTVGNIVRRAFCSAHVGYWIDEGVAGRGIMPTALALVCDHAFTTGQLHRIEVNIQPHNTPSRRVVEKLGFREEAQFKSYLYINGEWRDHVGYAMTVEDVTDGGVLARYLKRRTQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q464</accession>
    <name>D3Q464_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Cyclic pyranopterin monophosphate synthase</fullName>
            <ecNumber evidence="3 5">4.6.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor biosynthesis protein C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">moaC</name>
        <name evidence="7" type="ordered locus">Snas_6331</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer; trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MoaC family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.17" evidence="3 5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6331"/>
    <dbReference type="EnsemblBacteria" id="ADD45949">
        <property type="protein sequence ID" value="ADD45949"/>
        <property type="gene ID" value="Snas_6331"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6331"/>
    <dbReference type="eggNOG" id="COG0315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074693_1_1_11"/>
    <dbReference type="OMA" id="IWDMVKS"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01224_B">
        <property type="entry name" value="MoaC_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="Mo_CF_biosynth-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="SSF55040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaC" evidence="6">
        <location>
            <begin position="16"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="76"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="112"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="157" mass="16343" checksum="CBDC84E53DEADE53" modified="2010-04-20" version="1">MSKSLTHVDETGAAHMVDVAAKDVTARIATAAARLNTTAEVIEALRGDTLPKGDATAAARLAGIMGAKKTPDLIPLCHPIALHGVKVELEFGDTFVDITTRTKTADRTGVEMEALTAAAVAGLTLIDMVKALDPAASLTDVRVLSKEGGKTGSWRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4L8</accession>
    <name>D3Q4L8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0463</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40178">
        <property type="protein sequence ID" value="ADD40178"/>
        <property type="gene ID" value="Snas_0463"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0463"/>
    <dbReference type="HOGENOM" id="CLU_1229265_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="225" mass="25603" checksum="1E67508CF151874C" modified="2010-04-20" version="1">MYDIPESERQRIRGAQAGPFVPLVDWEANPFADPPRSQPYDAELPLRGFASEKALADRVLARLEPWFVIDREVRGTHCCGKHLRVDAMLRPRNAQVWADPDVAFGVEFKQPPLQAGENAYTKWLAQAVDYTHVDWDNYGHRLIFTCPGAAAWLDTAPAPNPHADPNRRRDVHIAKRLAGQLNLGELVLRWSSGLTFLLNGENIWSERFDVSNGRSWKLRRKIGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4M1</accession>
    <name>D3Q4M1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0466</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0466"/>
    <dbReference type="EnsemblBacteria" id="ADD40181">
        <property type="protein sequence ID" value="ADD40181"/>
        <property type="gene ID" value="Snas_0466"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0466"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_1_3_11"/>
    <dbReference type="OMA" id="HEFASAA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1028" mass="109563" checksum="E26F5929F4BC31C4" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q505</accession>
    <name>D3Q505_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017756.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2503"/>
    <dbReference type="EnsemblBacteria" id="ADD42185">
        <property type="protein sequence ID" value="ADD42185"/>
        <property type="gene ID" value="Snas_2503"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2503"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087580_2_0_11"/>
    <dbReference type="OMA" id="SNGRERW"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="182" mass="20527" checksum="E66BB32F48AA1B4A" modified="2010-04-20" version="1">MPSEPIPHTSATLKALASPLRRAILRHLATNGPANSTSIGEVFGHNTGTTSYHLRQLAQAGLITEIPERAKGRERWWRTEPGNRVMPDRDTMSAQDKVIAADLERSRLTEDMDALSGVLDNRAELGDWFQGSRSLRFMTKAELKEFHDDYLRLLDRHGHKPEDAPDTARPIALRWYGYPATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q587</accession>
    <name>D3Q587_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytidyltransferase-related domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019707.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4491"/>
    <dbReference type="EnsemblBacteria" id="ADD44136">
        <property type="protein sequence ID" value="ADD44136"/>
        <property type="gene ID" value="Snas_4491"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4491"/>
    <dbReference type="eggNOG" id="COG3172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052648_0_0_11"/>
    <dbReference type="OMA" id="QDPFRYW"/>
    <dbReference type="OrthoDB" id="693749at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038727">
        <property type="entry name" value="NadR/Ttd14_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13521">
        <property type="entry name" value="AAA_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA_28" evidence="1">
        <location>
            <begin position="156"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="359" mass="40166" checksum="8F8CD8E18C3E6222" modified="2010-04-20" version="1">MSRFRHGLVLGKFYPPHAGHHHVIRTGLAACERLTVLVCAASVESIPLARRVEWLREAHPLTTVVGAVDDVEVDVHDPAVWDAHMAIFRAAVPGRVDAVFTSEDYGAELARRFGAEHVAVDVDRGLFPVSGRRVRADPVGHWGFLEAPVRAGLARRVVVLGAESSGTTTLARGLAEHYAGRGGVWADTRWVPEFGREYSEAKLAALLVERPDAGWSEVRFDGDEFPFIARRQDEMEEAAARRGSPVLFCDTDSFATAIWHERYLGRGNAEVARIAERVERHLWILTDHDGVAFEDDGLRDGESLRGWMTRRFRDALRRTRRPFVEVSGSREQRLKQAVAAVDELLATGWRFADPLPERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5A6</accession>
    <name>D3Q5A6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4510</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4510"/>
    <dbReference type="EnsemblBacteria" id="ADD44155">
        <property type="protein sequence ID" value="ADD44155"/>
        <property type="gene ID" value="Snas_4510"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4510"/>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_0_2_11"/>
    <dbReference type="OMA" id="NNSAFMV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049555" evidence="2">
        <location>
            <begin position="25"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="3">
        <location>
            <begin position="57"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="317" mass="34111" checksum="614725B4C7E3A03A" modified="2010-04-20" version="1">MRISTSVRLAGVLLASLLAVSACASPEGNADTGEEKETRSVTDATGAKIKVPKEPERIVALSEQDLDSLLALDITPVGTVNGRGQKTPPAYLGDKAADIEVVGDVGKPTVDKIVELDPDLVLFGGAQDEKQLEKLRELVPATVVTYKLDDEWTEAFTKIADVVGAKKDGETWLTEYESKVEEAQGKLGDNAKSTVSIVRWNPDGPGIMQNEAFASLVIQDLGLKRPKDQQEPGFAHTDPLSLENLPRIDADWLFVGTLQPGAEKALKEAKKDSAFSELDAVKKDHFVEVDGTLWTSRGGPLASLQVIDDVVKNLGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5G1</accession>
    <name>D3Q5G1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit PurL</fullName>
            <shortName evidence="5">FGAM synthase</shortName>
            <ecNumber evidence="5">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Formylglycinamide ribonucleotide amidotransferase subunit II</fullName>
            <shortName evidence="5">FGAR amidotransferase II</shortName>
            <shortName evidence="5">FGAR-AT II</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glutamine amidotransferase PurL</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purL</name>
        <name evidence="9" type="ordered locus">Snas_6405</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FGAMS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6405"/>
    <dbReference type="EnsemblBacteria" id="ADD46021">
        <property type="protein sequence ID" value="ADD46021"/>
        <property type="gene ID" value="Snas_6405"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6405"/>
    <dbReference type="eggNOG" id="COG0046">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003100_0_1_11"/>
    <dbReference type="OMA" id="FIEPYQG"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00420">
        <property type="entry name" value="PurL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010074">
        <property type="entry name" value="PRibForGlyAmidine_synth_PurL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43555">
        <property type="entry name" value="PTHR43555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001587">
        <property type="entry name" value="FGAM_synthase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01736">
        <property type="entry name" value="FGAM_synth_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGAR-AT_linker" evidence="8">
        <location>
            <begin position="22"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS" evidence="6">
        <location>
            <begin position="103"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="7">
        <location>
            <begin position="218"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS" evidence="6">
        <location>
            <begin position="461"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="7">
        <location>
            <begin position="593"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="110"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="329"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="517"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="554"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="557"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD46021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="758" mass="80408" checksum="4FF58902E6D6EC17" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5H8</accession>
    <name>D3Q5H8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6422</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6422"/>
    <dbReference type="EnsemblBacteria" id="ADD46038">
        <property type="protein sequence ID" value="ADD46038"/>
        <property type="gene ID" value="Snas_6422"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6422"/>
    <dbReference type="HOGENOM" id="CLU_1081460_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD46038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="226" mass="23353" checksum="C0D33E92082B2091" modified="2010-04-20" version="1">MTYPPQPGGQDPYGQQQPGYGQQPGYSPQQPVTGVPSSPAGGYGQPAYPPQQPPGYGMGTPVPEPGDRPGMVTTAAMLMVAMTVISLLMGALGIYFSIEDANSSISEDAASVGRTVSIVVGVLYLVVGIGVIVLALGVLRGYNWARITTWVVYGLFALCGLCGLLGSFGILSETSTTSTDTTGGIIVMLGLVLMLVIEGITVGLLAAPVSNQWFREVSLAKRAGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5I9</accession>
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        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
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        <name evidence="8" type="ordered locus">Snas_6433</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="ADD46049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6433"/>
    <dbReference type="EnsemblBacteria" id="ADD46049">
        <property type="protein sequence ID" value="ADD46049"/>
        <property type="gene ID" value="Snas_6433"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6433"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_3_0_11"/>
    <dbReference type="OMA" id="LVDMQGY"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
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    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="28"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="123"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="181"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD46049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="22677" checksum="90FD7DC57F832686" modified="2010-04-20" version="1">MADLSGCDDKELLRRHATGGDRDAFGELFRRHRDRLWAVALRTLSDPEEAADALQDAMVNAYRAAARFRGDSAVTTWLHRIVVNACLDRVRRKQARPAVPMSDQLPEPAMPGADPADAAGVLAVRQALAELPFDQRAVVVYIDMLGYPVADVAAILEIPAGTVKSRASRARSQLATLLSEIGNRAPAGDVGPIAGPDAGDPATTTSGKEEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5J4</accession>
    <name>D3Q5J4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6438</name>
    </gene>
    <organism evidence="3 4">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6438"/>
    <dbReference type="EnsemblBacteria" id="ADD46054">
        <property type="protein sequence ID" value="ADD46054"/>
        <property type="gene ID" value="Snas_6438"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6438"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_439974_0_0_11"/>
    <dbReference type="OrthoDB" id="1907192at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028208">
        <property type="entry name" value="Effector_pro_NleD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14891">
        <property type="entry name" value="Peptidase_M91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="332"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="417"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="624"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="83"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="419"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="649"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD46054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="680" mass="72322" checksum="05FAC9D9CD74D2C2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5K9</accession>
    <name>D3Q5K9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021640.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6454"/>
    <dbReference type="EnsemblBacteria" id="ADD46069">
        <property type="protein sequence ID" value="ADD46069"/>
        <property type="gene ID" value="Snas_6454"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6454"/>
    <dbReference type="eggNOG" id="COG0365">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_10_11"/>
    <dbReference type="OMA" id="GPVGCRY"/>
    <dbReference type="OrthoDB" id="326708at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="56"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="447"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD46069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="529" mass="58160" checksum="D99CAF6746DF84BC" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5M1</accession>
    <name>D3Q5M1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_6466</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 87 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6466"/>
    <dbReference type="EnsemblBacteria" id="ADD46081">
        <property type="protein sequence ID" value="ADD46081"/>
        <property type="gene ID" value="Snas_6466"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6466"/>
    <dbReference type="eggNOG" id="ENOG5031JHI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041277_0_0_11"/>
    <dbReference type="OMA" id="APILITH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="410"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD46081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="425" mass="44309" checksum="9D3C8453483B566B" modified="2010-04-20" version="1">MERTTKGGLYLDFALYGVSAVFAIATALWSTLEPHRVWGGMATGGYLPAALLTLMLLFRYAVPVVTRMWITVAAAVAVTLMPLVGEAAQRAAGVAAMAQEEVLVVESGGVRLLETGSPYLSLAEIAKLPDALLGYNPYQPGMSVFGLPRALFGQNFLTDARIWFAVATLAATLAALTMLRRAGLTRGAWVRGLQAVGVLPICALTLATGGDDLPVVALCLLAFACVATGRFTGAGFAIGGAAALKLLAWPVLIVVLVLAFKRGRLLPLALPALALPLGTLAPILITHPAEYFANVIQFPLGNGLVASPAASPLPGHLIAAHLPSGRVFAIALLVLAGAAVGWLVLARPPATAFRAAGLSAVGLLAAILLLPATRFGYLLYPAVFGVWWWVLKQIEAPASQWGPHTDPASEGTEGTETAGDTRWSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5P9</accession>
    <name>D3Q5P9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015769.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0483"/>
    <dbReference type="EnsemblBacteria" id="ADD40198">
        <property type="protein sequence ID" value="ADD40198"/>
        <property type="gene ID" value="Snas_0483"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0483"/>
    <dbReference type="eggNOG" id="ENOG5032XQY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2044677_0_0_11"/>
    <dbReference type="OMA" id="ARYVAWG"/>
    <dbReference type="OrthoDB" id="1868844at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="120" mass="14264" checksum="A80896FEF1183A30" modified="2010-04-20" version="1">MKLRTDDDIYRARLLYLGPPGYTFPVHLPYAQYGVFAALLALYMFIHWLISFEVEIFPAWEIALAMVSTSLIFRYVDPDRPARAVIRTVLTDWRRTREPVAEQRDRRYSASRIRIRQELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5T2</accession>
    <name>D3Q5T2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0516</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0516"/>
    <dbReference type="EnsemblBacteria" id="ADD40231">
        <property type="protein sequence ID" value="ADD40231"/>
        <property type="gene ID" value="Snas_0516"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0516"/>
    <dbReference type="HOGENOM" id="CLU_956172_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="291" mass="31053" checksum="09814F145D267D90" modified="2010-04-20" version="1">MTDPLAPYNAGSDPLAPPPATPPASAVPVPEPKSVMEPRPAAPLEDAKPRVARPGTSRPDGPPASPGASVHEANVVDLPPLPRKRSLLWRIVSFSWELTIGVTIALVILVAGGVFYVVDWAKSLGPTYSAAELYEDGRYSMTVKDGDKVILDTYLDQVGAWDHDGCDSIATDKAVQSAVVEAGCEFGIEGVYERADLHYTIYQRILEFPDAGAAKRGGQALGDAEELPGKVSFSVEMPEDGKTGAVVDVEGRFVIFTVAAIEPEGEKNLAEAEEAIDALHTEHLNVLVWQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6A2</accession>
    <name>D3Q6A2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Riboflavin biosynthesis protein RibBA</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="13">3,4-dihydroxy-2-butanone 4-phosphate synthase</fullName>
                <shortName evidence="13">DHBP synthase</shortName>
                <ecNumber evidence="13">4.1.99.12</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="13">GTP cyclohydrolase-2</fullName>
                <ecNumber evidence="13">3.5.4.25</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="13">GTP cyclohydrolase II</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="13" type="primary">ribBA</name>
        <name evidence="15" type="ordered locus">Snas_2598</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18457"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="4.1.99.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 3 H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:23704"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">Binds 2 divalent metal cations per subunit. Magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 13">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">In the C-terminal section; belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 13">In the N-terminal section; belongs to the DHBP synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="13"/>
    <dbReference type="EC" id="3.5.4.25" evidence="13"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2598"/>
    <dbReference type="EnsemblBacteria" id="ADD42277">
        <property type="protein sequence ID" value="ADD42277"/>
        <property type="gene ID" value="Snas_2598"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2598"/>
    <dbReference type="eggNOG" id="COG0108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020273_1_2_11"/>
    <dbReference type="OMA" id="ECRGLIC"/>
    <dbReference type="OrthoDB" id="900513at2"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00179">
        <property type="entry name" value="RibA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00180">
        <property type="entry name" value="RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01283">
        <property type="entry name" value="RibBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016299">
        <property type="entry name" value="Riboflavin_synth_RibBA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="SSF142695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00505">
        <property type="entry name" value="ribA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydro2" evidence="14">
        <location>
            <begin position="209"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="DHBP synthase" evidence="13">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="13">
        <location>
            <begin position="28"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="13">
        <location>
            <begin position="141"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="GTP cyclohydrolase II" evidence="13">
        <location>
            <begin position="203"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for GTP cyclohydrolase activity" evidence="13">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GTP cyclohydrolase activity" evidence="13">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="253"/>
            <end position="257"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="297"/>
            <end position="299"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="site" description="Essential for DHBP synthase activity" evidence="13">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="site" description="Essential for DHBP synthase activity" evidence="13">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD42277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="405" mass="43585" checksum="62F08CEC2510B90E" modified="2010-04-20" version="1">MSMLDSVPDAIADIAAGRPVVVVDDEDRENEGDLIFAAEKATPELLAFMVRYTSGYICAPLTEADADRLELPPAHTVNQDPRGTAYTVTVDAGSGITTGISAADRARTIRLLADPETKPTDLRRPGHMVPLRAKDGGVLRRPGHTEAAIDLAVLAGLRPAGVLCEMVNDDGTMKRLPDLRAFADEHDLRVISIADLVAHRRRTEKQITRVAETRLPTEHGQFTAVGYRADLDGSEHVALVCGDIGDGTDVLVRVHSECLTGDAFGSLRCDCGPQLHSAMRAVATEGRGIVLYMRGHEGRGIGLLHKLRAYELQDQGRDTVDANLDLGLPADSRDYGTGAEILADLGVKSMRLLTNNPAKRAGIEGFGLSVTGRVPLAGAVRPENLAYLRTKRDRMGHLLDDLESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6A5</accession>
    <name>D3Q6A5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">ATP phosphoribosyltransferase</fullName>
            <shortName evidence="11">ATP-PRT</shortName>
            <shortName evidence="11">ATP-PRTase</shortName>
            <ecNumber evidence="4 11">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hisG</name>
        <name evidence="14" type="ordered locus">Snas_2601</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Feedback inhibited by histidine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ATP phosphoribosyltransferase family. Long subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="4 11"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017851.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2601"/>
    <dbReference type="EnsemblBacteria" id="ADD42280">
        <property type="protein sequence ID" value="ADD42280"/>
        <property type="gene ID" value="Snas_2601"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2601"/>
    <dbReference type="eggNOG" id="COG0040">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038115_1_1_11"/>
    <dbReference type="OMA" id="YVMMDYD"/>
    <dbReference type="OrthoDB" id="1419568at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP_PRibTrfase_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisG" evidence="12">
        <location>
            <begin position="49"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="HisG_C" evidence="13">
        <location>
            <begin position="206"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD42280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="281" mass="29994" checksum="2506090314890A58" modified="2010-04-20" version="1">MLRIAVPNKGSLSEAATQMLVEAGYRQRRAARDLTATDTANDVQFFYLRPRDIATYVASGDLDLGITGRDLLVDSAAEAEETMALGFGGSTFRYACRPGTASTVTDLEGKRIATSFTGVVRANLAANGVSATVVHLDGAVENAVGLGVADAVADVVSTGATLRQAGLEIFGEPLMESEAILIRRRGGSSNGAQDQLLRRLHGVMVARSYVMLAYDVLAEDLERACALTPGIESPTISPLHREGWVAVQSMTERAEVHRIMDDLYELGARGILVTDIHACRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6B4</accession>
    <name>D3Q6B4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2610</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017860.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2610"/>
    <dbReference type="EnsemblBacteria" id="ADD42289">
        <property type="protein sequence ID" value="ADD42289"/>
        <property type="gene ID" value="Snas_2610"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2610"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078424_1_0_11"/>
    <dbReference type="OMA" id="FIHEQVN"/>
    <dbReference type="OrthoDB" id="1377768at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="6">
        <location>
            <begin position="39"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="273" mass="28959" checksum="583E57642D049B94" modified="2010-04-20" version="1">MSIVYSTRPRLLGGFGNEIGKGLADLVAGWRGLAVQMITFPLFYLLIVLFMGRGQLRAELLLPVGIGMVALTFIHEQVNRMFWSYQGDIQSGVLEQTYLTPLPSWVLILGRQIASIVAALPTALSVGATGYVAIVANGGSVHFDPRVVVPLAAIAVGTCGLALVLCGLTLVYKRIQIITQVSVAVYAIAGGTLVPLTDMPGWTAVVARLAVPIAPGIEAMRDILLDGDSLAGLSTGWGPGWLLLQPLLIAGAGVLVFSRLERIAKRRGTLGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q727</accession>
    <name>D3Q727_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative thiol-disulfide oxidoreductase DCC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015997.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0714"/>
    <dbReference type="EnsemblBacteria" id="ADD40426">
        <property type="protein sequence ID" value="ADD40426"/>
        <property type="gene ID" value="Snas_0714"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0714"/>
    <dbReference type="eggNOG" id="COG3011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086500_5_1_11"/>
    <dbReference type="OMA" id="GDCAFCT"/>
    <dbReference type="OrthoDB" id="2019103at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007263">
        <property type="entry name" value="DCC1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04134">
        <property type="entry name" value="DCC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="126" mass="13759" checksum="64FEB4D41C57B286" modified="2010-04-20" version="1">MAEPVFLYDGDCAFCTRCVEFYRRHAATEVPILPWQAADLDALGLTAAECDTAVQWARPGAEPKAGPDAIARLLRASTGHLGAWKLAGLVLSFPPVRWLAWPGYRWVARNRHRMPGGTAACSLPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7A8</accession>
    <name>D3Q7A8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2702"/>
    <dbReference type="EnsemblBacteria" id="ADD42379">
        <property type="protein sequence ID" value="ADD42379"/>
        <property type="gene ID" value="Snas_2702"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2702"/>
    <dbReference type="eggNOG" id="ENOG5030RUJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_590390_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048292" evidence="1">
        <location>
            <begin position="30"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="463" mass="48127" checksum="3EA90233ABB0E739" modified="2010-04-20" version="1">MSKRKRPKKLVIGVATALALAIGGGGAWAGTSYLGTDGTDPESRLPASTAAFASFNLDVSKEQQQELLELVAKFPSAAVDSDLPQEAVSRFLEMLEKKDGDFADGRFSEWVGPNASVALWEYKGEPYGLASVSSIDDSKAEDGLAAVKQAGGNDQVGYQVKDGYATIAFGEKGAQKAAKTAVSEAEKAPLSESDRFAKADSFLGDDKVLSAWADLEQSYELLEKKLPEDGGGLPFDALKVLKNNMNGQIAVGAQARDYGIEAVSSTFGAKDVIEGKKGMIDDLSQLPESDIGAALALPQDVKESILMVLVNSGFGEIGEGLDNVIMDKVSELLSGASGTLSVNGVKTSTPSGMAVIETTSPDKARALKALADLAGGALKTSVEGSTITGSTVGYSGDGKISDNKYYKDAVGGAVDKLNGAVFVDVTKMPLGNAEQALEAVKAIGITHGTKGGEYVGNYRLIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7N0</accession>
    <name>D3Q7N0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mn2+dependent serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019943.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4730"/>
    <dbReference type="EnsemblBacteria" id="ADD44372">
        <property type="protein sequence ID" value="ADD44372"/>
        <property type="gene ID" value="Snas_4730"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4730"/>
    <dbReference type="eggNOG" id="COG3642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083624_0_0_11"/>
    <dbReference type="OMA" id="VVIDWTN"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="4"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="108"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="216" mass="23835" checksum="92F0BEB25A794445" modified="2010-04-20" version="1">MELLAQGRDADVYALDDERVLRRCRHGEPSQTEIRIQSHVRQAGYPVPEIFDVSGRDIVMERLHGPSLMETMLDGAEDGVATLAEVHNRLHELSAPDWLRGHDSGGDRIAHLDLHPANVIVTESGPVVIDWTNAVAAHPGLDVADTIVVLSVAIPDGVDLAVLDAGRRRLTEEFAAKVDHDPNPWLPTAIRQRMVNPNLKPAEGQLLRDWLSELES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q804</accession>
    <name>D3Q804_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0797</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016080.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0797"/>
    <dbReference type="EnsemblBacteria" id="ADD40509">
        <property type="protein sequence ID" value="ADD40509"/>
        <property type="gene ID" value="Snas_0797"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0797"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="VHELVAF"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1001" mass="109172" checksum="AF61CA972A10FA7D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q862</accession>
    <name>D3Q862_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016138.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0856"/>
    <dbReference type="EnsemblBacteria" id="ADD40567">
        <property type="protein sequence ID" value="ADD40567"/>
        <property type="gene ID" value="Snas_0856"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0856"/>
    <dbReference type="eggNOG" id="COG0767">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045686_2_0_11"/>
    <dbReference type="OMA" id="NYLVFPK"/>
    <dbReference type="OrthoDB" id="1253502at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="253" mass="26296" checksum="BF0D869FD307A053" modified="2010-04-20" version="1">MGRMFAGVGRFTGFTIDTFKAVPRRPFQWSEAIKQAWFIASVSILPTALVAIPFGAVIALQLGSLSKQIGAESFAGAASVLAVVREAGPIVTALLISGAGGSAMCADLGARKIREELDAMETLGVDPIQRLVVPRMFAGAVVAFFLNGVVSAVGIAGGYIFNVYMQDGTPGSYLASFAALGQVADVVSAQLRAIVFGMVAALIACYLGMNAKGGPKGVGQAVNVSVVVNFMVLFAFNFVMVALYFQLVPQKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q868</accession>
    <name>D3Q868_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucose sorbosone dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018013.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2766"/>
    <dbReference type="EnsemblBacteria" id="ADD42442">
        <property type="protein sequence ID" value="ADD42442"/>
        <property type="gene ID" value="Snas_2766"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2766"/>
    <dbReference type="eggNOG" id="COG2133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012253_0_0_11"/>
    <dbReference type="OMA" id="KRMFATD"/>
    <dbReference type="OrthoDB" id="567019at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048306" evidence="1">
        <location>
            <begin position="30"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="GSDH" evidence="2">
        <location>
            <begin position="56"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="357" mass="38411" checksum="5747EAD9E4BD3ACA" modified="2010-04-20" version="1">MNRRTILSLTVAVATVGIAATGGIAVAHAETEPDAKTGVESEFDFSKPEVMAEGLKVTWGMAYLPNGEVLFTQREKAEIYRMKPGHKPKLVTKIKECTPGSSLEAGLTGIAVSPDYKDDGEIFIYYTAADGNRIASLSLKDPEPESIVTGIPTGTMHDGGRLRFGPDDMLYATTGDTGKGELAQDPDSLAGKILRMEPDGDVPDDNPFEDSLVYSLGHRNVQGLDFDSHGQPYASELGLDTADEVNKIEAGGNYGWPKYEGPGGDPDYIDPIATWTPAEASPAGMAIADETLYVGALRGQRLWMVSQDGETQDALVGDEGYGRLRAVEYGPDGYLWVATSDREQPNGDMIVRFPPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8B6</accession>
    <name>D3Q8B6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA ligase (ATP)</fullName>
            <ecNumber evidence="1">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2814</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.5.1.1" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018061.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2814"/>
    <dbReference type="EnsemblBacteria" id="ADD42490">
        <property type="protein sequence ID" value="ADD42490"/>
        <property type="gene ID" value="Snas_2814"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2814"/>
    <dbReference type="eggNOG" id="COG1793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008325_4_0_11"/>
    <dbReference type="OMA" id="RWAYETK"/>
    <dbReference type="OrthoDB" id="1073940at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="4">
        <location>
            <begin position="97"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="286"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="358" mass="37936" checksum="77E5A3A3F7237275" modified="2010-04-20" version="1">MLPTPGTLPEGPGWGFEFKWDGMRTLIATADGRARMIARGGGDYASAFPDLADIADQLPEGVIDAEIIALDASARPSFSRVAKRFSNRHPPPDLVRSVPVNLMIFDLLRLGDAEVVGQPYWRRREVLDALELVGERWLVPPWHDDGAGTLAAALDAGLEGVVAKRLDSRYVAGRSRDWVKVKAVDTGDVVVGGWRTAIRSLLVGTPNAAGTLTYRGRVGSGLTDAELGRFRAELAPSDACPFDPPPPGDHARDAIWTAPVAVVEVAFSHLTRSGLMRHPRYVRARPDKTAADIDPAAMDPGASDSGPIDPRAIDPGASDSSTIAPAAIDRSSTDAIASDPDAIGSGLIEPDGDETGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8F5</accession>
    <name>D3Q8F5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SIS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018100.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2854"/>
    <dbReference type="EnsemblBacteria" id="ADD42529">
        <property type="protein sequence ID" value="ADD42529"/>
        <property type="gene ID" value="Snas_2854"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2854"/>
    <dbReference type="eggNOG" id="COG4821">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089975_0_0_11"/>
    <dbReference type="OMA" id="FHPIVEL"/>
    <dbReference type="OrthoDB" id="1605411at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05013">
        <property type="entry name" value="SIS_RpiR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035472">
        <property type="entry name" value="RpiR-like_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13580">
        <property type="entry name" value="SIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="1">
        <location>
            <begin position="34"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="250" mass="25819" checksum="581CE2661D670BC8" modified="2010-04-20" version="1">MSVSAAAYAAAITEVCDRAVATQTDAVNAAADLIAGSLKRGGILQAFGTGHSEALCMELAGRAGGLVPSNRIALRDLVLRGGEDAELLSSDKLERDPQVARRLFALSEAAPEDVFVIASQSGINGSIVEFASAVKEAGHDLIAFTSTQHSGQTPSRHPSGRKLAELADVVIDNCAPYGDALLDLPEGGSVCAASSISAALLANMVVAEVVRRQLDVGETPPVYLSANVPGGDTHNNTLESRYAGRIRRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Q7</accession>
    <name>D3Q8Q7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MgtC/SapB transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_4858</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MgtC/SapB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4858"/>
    <dbReference type="EnsemblBacteria" id="ADD44499">
        <property type="protein sequence ID" value="ADD44499"/>
        <property type="gene ID" value="Snas_4858"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4858"/>
    <dbReference type="eggNOG" id="COG1285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079292_0_1_11"/>
    <dbReference type="OMA" id="LTCAIGM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33778">
        <property type="entry name" value="PTHR33778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01837">
        <property type="entry name" value="MGTCSAPBPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="23009" checksum="A2FE84F616ADA1C3" modified="2010-04-20" version="1">MFWTQLGLLALAVLLGTLIGAEREFEGKPAGMRTHAIIAVGAALFTLASKYGFPGADGEVTDTSRIAAQIVSGIGFLGAGVIFFHRNLVFGMTTAASIWSTTAIAMVCTAGMPLIAVGATVVHLGIVSGLQPLERFIGRYAKHSGRLRLTYTTGKALEDALKLCTSRGFTVTEVSTERTGEDDVRKTTLTVRGRGNIGKLTSALSDAEHVRGVSLHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8S5</accession>
    <name>D3Q8S5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4876"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44517">
        <property type="protein sequence ID" value="ADD44517"/>
        <property type="gene ID" value="Snas_4876"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4876"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_5_11"/>
    <dbReference type="OMA" id="FDAEQPF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="178"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="370" mass="39299" checksum="DC3AE9FF3748AD46" modified="2010-04-20" version="1">MLVTNDFPPRQGGIQSFVHGMATRLPVEHLVVYCSTSPGAAAFDAEQPFPVVRARTSMLLPTPGAARAAARVAVEHDCDAVWFGAAAPLGLLAAGLKRRTAIRRAVALTHGHEVGWAKLPVARTALRRIARGCDVVTYLAEYSRARLAPAIDALTSLEQLTFGVDTGEFSPTVDRAAIRRRFGLGDRPVIGCVSRLVPRKGQDSLVEALPLVRERVPDAALLLVGGGPYEKALRRRIAAAGMGDHVVLTGPVPGSELPACYAAMDVFAMPCRTRRRGLDVEGLGVVYLEAAATGLPVIAGDSGGAPDTVRHGETGFVVDGRDIPALADRLSTVLGDRELAARMGAAGRDWMCRAWTWPTVAERLAKLLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8T3</accession>
    <name>D3Q8T3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chitinase</fullName>
            <ecNumber evidence="5">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4884</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.14" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020096.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4884"/>
    <dbReference type="CAZy" id="GH19">
        <property type="family name" value="Glycoside Hydrolase Family 19"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44525">
        <property type="protein sequence ID" value="ADD44525"/>
        <property type="gene ID" value="Snas_4884"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4884"/>
    <dbReference type="eggNOG" id="COG3179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045506_4_1_11"/>
    <dbReference type="OMA" id="TISTWYW"/>
    <dbReference type="OrthoDB" id="1584918at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016283">
        <property type="entry name" value="Glyco_hydro_19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000726">
        <property type="entry name" value="Glyco_hydro_19_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00182">
        <property type="entry name" value="Glyco_hydro_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001060">
        <property type="entry name" value="Endochitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048761" evidence="3">
        <location>
            <begin position="31"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_19_cat" evidence="4">
        <location>
            <begin position="44"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="117"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="213"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001060-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001060-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="245" mass="26321" checksum="B2E7313571269203" modified="2010-04-20" version="1">MRRRPALLTIAAAAIISALALVFPTATAQADDDSTPDTEAAFVVSEAQFNQMFPNRNPFYTYEGLTTAMNSYPEFANSGGDTVMKQEAAAALANFSHETGGLVHIVEQDQSNYPHYCDTTQPYGCPAGNDAYYGRGPIQLSWNFNYKAAGDNLGIDLLNNPWQVEQNAAVAWQTGLWYWMTQNGPGSMTAHNAMVNGAGFGETIRAINGSLECNGGNPGQVQSRVDKYKAFTAILGVDPGGNLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8X3</accession>
    <name>D3Q8X3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase S41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016153.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0871"/>
    <dbReference type="MEROPS" id="S41.952"/>
    <dbReference type="EnsemblBacteria" id="ADD40582">
        <property type="protein sequence ID" value="ADD40582"/>
        <property type="gene ID" value="Snas_0871"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0871"/>
    <dbReference type="eggNOG" id="COG0793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044498_0_0_11"/>
    <dbReference type="OMA" id="SGTNWEG"/>
    <dbReference type="OrthoDB" id="1646508at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TSPc" evidence="1">
        <location>
            <begin position="80"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="300" mass="32444" checksum="0F4B9C85830302F2" modified="2010-04-20" version="1">MDNPEIINRTRELLVDHYVFPDVASRVVAVLTEAEAAGRYRDATEPATLGKIVTEDLQSINQDKHLRLKFHAEEQPDLPSEELMAAEARRDAQRGMHGIGRVERLEGNIAVVDVDRLHPTSISGEVFAAVMTLIADADGLVIDLRKCSGGHPGTVALVCSYLFGDEPVHLNGMYERHSDRTTQSWTLPFVPGKRYGPDKPICVLTSAVTFSGGEELAYDLQQLGRATIVGESTGGGAHPRVGFRLHPHLELTVPVARSIHPVTGTNWEGVGVAPDVAVPAEDALETATGLLRERLAEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q905</accession>
    <name>D3Q905_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016185.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0903"/>
    <dbReference type="EnsemblBacteria" id="ADD40614">
        <property type="protein sequence ID" value="ADD40614"/>
        <property type="gene ID" value="Snas_0903"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0903"/>
    <dbReference type="eggNOG" id="ENOG502ZBR0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1266249_0_0_11"/>
    <dbReference type="OrthoDB" id="1491938at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="23488" checksum="85D619F1FE7167AC" modified="2010-04-20" version="1">MLRLLTALLAGIFVGGVGLDLLTDAEGIAWIWPTTLPFLIIGLTLALVGNSLRGVLPLKDEQVRALLDQNLGALARITGIKRTGTSINDAPLCELDLVVAPFDRGAYATTVRALVDPVEIPRFQPGSVVVVARLRADRPEVSLIREPDAEWRRRANTESDRIPRRNRVSVWEADHRDAPGPRSLVGVGPEGRGQRLTAYAVLFVVGVAIVLGPNASAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q907</accession>
    <name>D3Q907_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016187.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0905"/>
    <dbReference type="EnsemblBacteria" id="ADD40616">
        <property type="protein sequence ID" value="ADD40616"/>
        <property type="gene ID" value="Snas_0905"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0905"/>
    <dbReference type="eggNOG" id="COG3568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060500_5_0_11"/>
    <dbReference type="OMA" id="PGWNRRQ"/>
    <dbReference type="OrthoDB" id="1387978at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048328" evidence="1">
        <location>
            <begin position="35"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="44"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="278" mass="29813" checksum="5508E0DD294196A2" modified="2010-04-20" version="1">MRQRQFAVSRRSLLGGLAIGAIGVTLGAPGTASARRAEARFGCFNIHHGASPDDVMDLERIARRIEALNCDVIGLQEVDRFWKRSGFVDEPAWLAERLGLEVAFGANLDLAPEEPGRPRRQYGTAVLSRWPIAESENTLLPKSGDDEQRGLLRTVLDAPGGAFVFANTHLQHGTDESVRVAQAELIIEILGDAPQRTVLVGDFNAEPGAESIDVIANRLPDAWAAAGDGDGLTYPSDNPHARIDFVFAAPDVKPAAMAVDAEDPSASDHLPLSGTFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9B7</accession>
    <name>D3Q9B7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Purine nucleoside phosphorylase</fullName>
            <shortName evidence="1">PNP</shortName>
            <ecNumber evidence="1">2.4.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2924</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Purine nucleoside phosphorylase involved in purine salvage.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19805"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer. Dimer of a homotrimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018170.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2924"/>
    <dbReference type="EnsemblBacteria" id="ADD42599">
        <property type="protein sequence ID" value="ADD42599"/>
        <property type="gene ID" value="Snas_2924"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2924"/>
    <dbReference type="eggNOG" id="COG0005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054456_0_2_11"/>
    <dbReference type="OMA" id="ADPFCPE"/>
    <dbReference type="OrthoDB" id="1364220at2"/>
    <dbReference type="UniPathway" id="UPA00606"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09010">
        <property type="entry name" value="MTAP_SsMTAPII_like_MTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01963">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010044">
        <property type="entry name" value="MTAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42679">
        <property type="entry name" value="PTHR42679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01694">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="2">
        <location>
            <begin position="7"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="1">
        <location>
            <begin position="54"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="1">
        <location>
            <begin position="87"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="209"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="1">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="1">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="263" mass="27963" checksum="C8F6DCE78ABB6CF0" modified="2010-04-20" version="1">MSASVTRLGIIGGSGLYELLDDPRYVEPETPYGPASAPIALGRLSGREVAFLPRHGASHEHPPHRVNYRANLWALDSLGVTRVIGVSAVGSLDPAIEPGTLVVPDQVVDRTHGRDGTYFDGPRVAHASFADPYCVAGRELAVDTVRSQGWPMRDAGTLVVIGGPRFSSRAESLWYQAQGWSIVGMTAMPEVALARELGLCYVPLCLVTDVDAGVAVGEGVTQEEVFAAFAANIARIRELLRDLVAKVGDGPDRACAALKPQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9D6</accession>
    <name>D3Q9D6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exonuclease RNase T and DNA polymerase III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2943"/>
    <dbReference type="EnsemblBacteria" id="ADD42618">
        <property type="protein sequence ID" value="ADD42618"/>
        <property type="gene ID" value="Snas_2943"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2943"/>
    <dbReference type="eggNOG" id="COG0272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029910_2_1_11"/>
    <dbReference type="OMA" id="CTMRLAG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="1">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="410" mass="45099" checksum="9C1938E31A049A1B" modified="2010-04-20" version="1">MYAVFDTETTGIIPGMHHRIIEIAVVLADDEGSIENTWSTLLNPDRDLGPQHIHGIKARQVIDAPKFGDIAGQLIQMLSGRTLVAHNLPFDLRFLSAEFERLGHQLTYNHHLGVCTMNWSTTFLEGASRSLPECCKAAGVQLTGWHSALSDAEATAALLKHYINAARGGVPWHDRLPLSRSCTWPTVPVTNAHVRQRESVPHKPSHGDPFISALVDYLPRVQSSEVSDPYLAVLDEALSDRYLSADETAALRALATSLQISDVQTRQLHHDYLEALARVALADHHLSAEEEEDLRQVAGILDLPLEAIDLAIKAAQALSKDSDTTPLPIAPGDMVVFTGTMPESREEWEQRAIEHGFVPHRAVTKKVKLVIAADSDSLSGKAKKARGYNIPIMDVDRFREVLGYPAPAAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9I2</accession>
    <name>D3Q9I2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018235.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2990"/>
    <dbReference type="EnsemblBacteria" id="ADD42664">
        <property type="protein sequence ID" value="ADD42664"/>
        <property type="gene ID" value="Snas_2990"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2990"/>
    <dbReference type="eggNOG" id="COG2220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070266_1_0_11"/>
    <dbReference type="OMA" id="FDGYTVE"/>
    <dbReference type="OrthoDB" id="767622at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048340" evidence="1">
        <location>
            <begin position="36"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="53"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="318" mass="34955" checksum="4A3B44D172FA8303" modified="2010-04-20" version="1">MTDRNHRSFALSRRSLVKWGGAAALAASIPVTIAAATAGAEPTGKSVRLRWLGTNSWEFTTEETTVLIDPWVSRFPTGAYTEAGANPETKIEVHEDVIDEHLPKADTILVTHGHWDHIADVPYIAKKTGATVIGTETHLNLLRAMDAPEEQLGQVVGGEFYQFKGCTVEVFKSTHSAKGDHKKIEFAGTRTSVPKRPMKIKHLVEGGSLTYLLDFGGVSFFNAGSANFHQHQTEGLTPTVLFIQPGGGHTPDYVERLLKATGYPRYVVPTHWDDFDKPLTEPAVPGGDIETLQKRVAKASPDSEFVRIDHLEHHDFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9J2</accession>
    <name>D3Q9J2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Deoxyribose-phosphate aldolase</fullName>
            <shortName evidence="3">DERA</shortName>
            <ecNumber evidence="3">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphodeoxyriboaldolase</fullName>
            <shortName evidence="3">Deoxyriboaldolase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">deoC</name>
        <name evidence="4" type="ordered locus">Snas_3002</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018245.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3002"/>
    <dbReference type="EnsemblBacteria" id="ADD42674">
        <property type="protein sequence ID" value="ADD42674"/>
        <property type="gene ID" value="Snas_3002"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3002"/>
    <dbReference type="eggNOG" id="COG0274">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053595_0_2_11"/>
    <dbReference type="OMA" id="MNACIPP"/>
    <dbReference type="OrthoDB" id="1227369at2"/>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00114">
        <property type="entry name" value="DeoC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028581">
        <property type="entry name" value="DeoC_typeI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="PTHR10889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="PTHR10889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="3">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="231" mass="24218" checksum="65126E0C37362BBC" modified="2010-04-20" version="1">MRTVAEVARMIDHSLLRPELTTGDIETGCALAARYRVASVCVRPADVPLAATALAGTGVLVGTVVGFPHGGNATAVKEAETRLAIEQGATEIDMVLNIGRLRSGQLDDVEADIRAVVTAAASAPVKVILENAYLTDEQKIAGCRAAERAGTRFVKTSTGFADGGATMADLRLMRATVSDTVEVKAAGGVRSLDTLLAMADLGVTRFGATVTDRILDDLDHRLRDRDGWTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9J4</accession>
    <name>D3Q9J4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42676">
        <property type="protein sequence ID" value="ADD42676"/>
        <property type="gene ID" value="Snas_3005"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3005"/>
    <dbReference type="HOGENOM" id="CLU_2525937_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="84" mass="8984" checksum="F4609782CA9EC63F" modified="2010-04-20" version="1">MANTSTTDMPSESTGQRTETRGATTEAKPDDVQPTQSDAEESQLTKVSHTVIEQLPDKRHLAYYAGLAGLAAFGVMSWPTARGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9M1</accession>
    <name>D3Q9M1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4926"/>
    <dbReference type="EnsemblBacteria" id="ADD44567">
        <property type="protein sequence ID" value="ADD44567"/>
        <property type="gene ID" value="Snas_4926"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4926"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061533_2_0_11"/>
    <dbReference type="OMA" id="CHGVLEY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="38"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="252" mass="25788" checksum="FE6582CD4E3ECF95" modified="2010-04-20" version="1">MDALKAVPSSRLAVVWSVVTGELARPMDCDTVEGPCRVVDVGGGTGGFAVPLAQAGYEVTVVDPSPNALAGLTRRAADAGVAERVTAVQGDTDALTGLVEPGSVRLVLCHSVLEMVDSPQLSMDAIASVLAPGGAASILGANRVGAVLSRALIGNLSAAMALLNDPDGRVGERDTLCRRFDPEELVTLVASGGLTVEQRHGVQVLADMTPGGRDTEPGAAQALREFEAATAALAPYRDIATHIHVLARKPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9S1</accession>
    <name>D3Q9S1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4979"/>
    <dbReference type="EnsemblBacteria" id="ADD44617">
        <property type="protein sequence ID" value="ADD44617"/>
        <property type="gene ID" value="Snas_4979"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4979"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_27_5_11"/>
    <dbReference type="OMA" id="EIVTPIW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="33"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="23259" checksum="B2B071D641A2FF05" modified="2010-04-20" version="1">MTDSYPLDQHAALPAEDIAAAWTRERPGAPVGSIRVITPLWRIAKRLADHRRALLTRAGADAATLDLLSTLRRSGTPYTMTTRQLAEATLVTAGAISQRVARAEREGLVTRARSTTRARSVEVTLTEAGHALVESLVDDILVSEDDLLDGLDEPQREQLAALLATWWESLRQRDLPSYQPFGFVRLASRPGPSPVTLSSDTRHRPVSEGDFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Z2</accession>
    <name>D3Q9Z2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0994</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0994"/>
    <dbReference type="EnsemblBacteria" id="ADD40704">
        <property type="protein sequence ID" value="ADD40704"/>
        <property type="gene ID" value="Snas_0994"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0994"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="995" mass="108964" checksum="2962CA8CB10A1C58" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA12</accession>
    <name>D3QA12_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Holo-[acyl-carrier-protein] synthase</fullName>
            <shortName evidence="8">Holo-ACP synthase</shortName>
            <ecNumber evidence="8">2.7.8.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">4'-phosphopantetheinyl transferase AcpS</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">acpS</name>
        <name evidence="10" type="ordered locus">Snas_1014</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>apo-[ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="EC" id="2.7.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the P-Pant transferase superfamily. AcpS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016295.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1014"/>
    <dbReference type="EnsemblBacteria" id="ADD40724">
        <property type="protein sequence ID" value="ADD40724"/>
        <property type="gene ID" value="Snas_1014"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1014"/>
    <dbReference type="eggNOG" id="COG0736">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089696_0_0_11"/>
    <dbReference type="OMA" id="LGVRSWH"/>
    <dbReference type="OrthoDB" id="1893660at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00516">
        <property type="entry name" value="acpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="9">
        <location>
            <begin position="5"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD40724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="122" mass="12887" checksum="03EA92A83227B29B" modified="2010-04-20" version="1">MIVAVGIDVVLVERFAKAVQRTPLLASRLFTESEQLTAAGNPRSYESLAARFAAKEAVAKALGAPGGLHWHDCEIVADPDGRPWLTVSGSVAEAATERGVERWHLSLSHDGGIASAIVVAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA15</accession>
    <name>D3QA15_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Transposase, IS605 OrfB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Snas_1017</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the transposase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1017"/>
    <dbReference type="EnsemblBacteria" id="ADD40727">
        <property type="protein sequence ID" value="ADD40727"/>
        <property type="gene ID" value="Snas_1017"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1017"/>
    <dbReference type="eggNOG" id="COG0675">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032903_0_0_11"/>
    <dbReference type="OMA" id="DYTGGRM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="15">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_IS605" evidence="13">
        <location>
            <begin position="167"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="14">
        <location>
            <begin position="292"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="379"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="207"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ADD40727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="406" mass="46334" checksum="ABDB8C3A8D2D4B95" modified="2010-04-20" version="1">MRTAYKCRAYPDSEQAAMLSRTFGCVRLVWNKTLAERHHRYHSEGRRTSYRETDATLTAWKKTRELAFLSEVSSVPLQQTLRHQHAAFANFFAGGAKYPRFKNRNWRQSAHYTRAAFRMRDGQLWLAKASAPLRFVWSWDNIDLVALKPTTVIISREPDGRWYVAFAVDIDAPAPLEETKHAVGIDVGIKNFAVTSDGERIRNPCHLERKSRNLARYQRRMARCQRGSMNRRKAKAKVARTHRKVRNARQDFLHRTSANLVRKADIVVVEDLGVRNMVRNRRLARAISDAGWSEFRRQLEYKCQRAGRRLVVIDRHYPSSKTCNACGHLLAKLNLGTRAWTCPSCRARHDRDHNAAKNILAAGLAVAAAESRSDACGADIRRQGPALPRSAANQETHPVRGVTPHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAJ3</accession>
    <name>D3QAJ3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018347.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3105"/>
    <dbReference type="EnsemblBacteria" id="ADD42776">
        <property type="protein sequence ID" value="ADD42776"/>
        <property type="gene ID" value="Snas_3105"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3105"/>
    <dbReference type="eggNOG" id="ENOG502ZIJG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1045545_0_0_11"/>
    <dbReference type="OMA" id="LYRREND"/>
    <dbReference type="OrthoDB" id="1036432at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046105">
        <property type="entry name" value="DUF6042"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19508">
        <property type="entry name" value="DUF6042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="275" mass="31541" checksum="4DB7690CC11708DA" modified="2010-04-20" version="1">MSFEYLQPTLRSDWDRTGWSRFLPFEGEVLWHVFCDATQWGIDGDIAVLFDWQESMHPVLSPGAGEREWLPEPRRRRPPRRVIARLLADSGEEYPTTVGEVAELGVSLGLYRRENDGTTVRWRVPAALPLPTEVLPMTLRQRRVEDEYRWLLGGAEIARDLAEYLVDCGEAPESVTSVRHLADSLHCEPDSVRHGLEYLCAPLAGGAFIRVYLGNGSRRRRQVSPERLDVDDPCVIVPQWRKLWKRFGLVWHLEGRGEFLLLGHPVQPLPDEGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAJ9</accession>
    <name>D3QAJ9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3111</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018353.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3111"/>
    <dbReference type="EnsemblBacteria" id="ADD42782">
        <property type="protein sequence ID" value="ADD42782"/>
        <property type="gene ID" value="Snas_3111"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3111"/>
    <dbReference type="eggNOG" id="COG3845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_86_7_11"/>
    <dbReference type="OMA" id="LAYGMEQ"/>
    <dbReference type="OrthoDB" id="870493at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="290"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="322"/>
            <end position="329"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="540" mass="57459" checksum="760E16323F58C9F7" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAM2</accession>
    <name>D3QAM2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018376.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3134"/>
    <dbReference type="EnsemblBacteria" id="ADD42805">
        <property type="protein sequence ID" value="ADD42805"/>
        <property type="gene ID" value="Snas_3134"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3134"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_5_4_11"/>
    <dbReference type="OMA" id="ETWVYPG"/>
    <dbReference type="OrthoDB" id="1581636at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="32"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="216" mass="23099" checksum="1DB7BBD47ECE415F" modified="2010-04-20" version="1">MEYTGDVYPGGPAAIRELETLTITKFSVSMMDNNVYLLRCRATGQQLLIDAADEPERIMEFVGDAGLSTVVTTHRHWDHIRATAAIVERTGAASLAHPADAGDVPAVTGTVDDGGTISCGDVTIEAIHLAGHTPGGLALLYRDPGGHPHLFTGDSLFPGGVGKTQTAADFDSLYTDVETKVFGRLPDDTWVYPGHGDDTTLGAERPKLPEWRARGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAP5</accession>
    <name>D3QAP5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">5-carboxymethyl-2-hydroxymuconateDelta-isomerase</fullName>
            <ecNumber evidence="2">5.3.3.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.3.3.10" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020262.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5055"/>
    <dbReference type="EnsemblBacteria" id="ADD44691">
        <property type="protein sequence ID" value="ADD44691"/>
        <property type="gene ID" value="Snas_5055"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5055"/>
    <dbReference type="eggNOG" id="COG0179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028458_3_1_11"/>
    <dbReference type="OMA" id="AKHIDYG"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008704">
        <property type="term" value="F:5-carboxymethyl-2-hydroxymuconate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="78"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="288" mass="30548" checksum="5243B4C96A6174A5" modified="2010-04-20" version="1">MRFVSYLHDGAETLGVAVGDRVVPTAALSADLPTTMAGLIATPDAVAAVERLAAEVPSGTGTPIIELSLLAPLPRPGNIVCIGQNYREHAEEQDKEAPAEPAIFLKHTASVTNPNATIAWDPAYATQVDYEAELAVVIGRTARNVTEADALSHVFGYTCLNDVTARDLQFGDLQWARGKSLDTFCPMGPVLVTPDEIGDPQSLTVKCLLNGTVVQEASTAVMYHSVARIIAHCSRAFTLRPGDVIATGTPGGVGIFRDPPLLLGDGDEVVVEIEKIGRLSNRCHTRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAP9</accession>
    <name>D3QAP9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, IclR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5059</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020266.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5059"/>
    <dbReference type="EnsemblBacteria" id="ADD44695">
        <property type="protein sequence ID" value="ADD44695"/>
        <property type="gene ID" value="Snas_5059"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5059"/>
    <dbReference type="eggNOG" id="COG1414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_6_3_11"/>
    <dbReference type="OMA" id="SRISATC"/>
    <dbReference type="OrthoDB" id="370329at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="15"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="77"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="263" mass="27513" checksum="B8053442738694D5" modified="2010-04-20" version="1">MNETAARNWDSAKPAPAVLRAGAVLRALAASGGRALSAAELATAADIPRSSAMNVCVALTQIGLVRAVSGGFALGPGLTELSQAYLDALDPVREFGTRTRAMNQIDETLQLGTLEGTDVVYLALHGGRMPLRITSRVGSRISATCTALGKAMLAAQTDTRVRALLESRQPFVSHTENSITDIDTLLADLDATRQRGYAVDAEETTWGITCLAVAVPGLPDGAQPFAVSTSLLTSQAKPERVDSLVRLIRELVTEIGAGSGSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB49</accession>
    <name>D3QB49_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016437.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1156"/>
    <dbReference type="EnsemblBacteria" id="ADD40866">
        <property type="protein sequence ID" value="ADD40866"/>
        <property type="gene ID" value="Snas_1156"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1156"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_45_3_11"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="227" mass="24984" checksum="E894ADA3AED67EAF" modified="2010-04-20" version="1">MARTVDETAHGLKRDAYLDAMERLLQSKGFTAVTIADILKETGSSKGAFYHYFDSKTALLEGVQLRLLDRVAAIVDPVIAAEASALEKLANFSAVVVRWKNANRKLLLESARAWYGPDNALPRERMRGLGRDWLAGQLAQVIRQGNAEGVFDSPRPDVDARLAVVTLQDLQETLVGWIIGRHPDAAERAAIHDTIDGYHHALERLLGAAPGSIHIVPKGVVDDWFQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB79</accession>
    <name>D3QB79_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplD</name>
        <name evidence="7" type="ordered locus">Snas_1186</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016467.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1186"/>
    <dbReference type="EnsemblBacteria" id="ADD40896">
        <property type="protein sequence ID" value="ADD40896"/>
        <property type="gene ID" value="Snas_1186"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1186"/>
    <dbReference type="eggNOG" id="COG0088">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041575_5_0_11"/>
    <dbReference type="OMA" id="PQVHILE"/>
    <dbReference type="OrthoDB" id="1572673at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_L4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4/L1e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="PTHR10746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="45"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="217" mass="23341" checksum="1D4F4FD92FF08327" modified="2010-04-20" version="1">MSLEVNVTDATGKKTGTVTLPAELFEREVNIHLMHQVVTAQLAAKRQGTHATKTRGAVSGGGAKPYRQKGTGRARQGSTRAPQFAGGGTVHGPQPRDYSQRTPKKMKAAALASALSDRAASEVVHVVTGLLDGDTPKTKDALKALRATTEAKKVLMVLDREDELTWKSLRNDPNVHLLFHDQLNTYDVLVNDALVFSKAAFDDFVAARTGEKQEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBA2</accession>
    <name>D3QBA2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016490.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1209"/>
    <dbReference type="EnsemblBacteria" id="ADD40919">
        <property type="protein sequence ID" value="ADD40919"/>
        <property type="gene ID" value="Snas_1209"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1209"/>
    <dbReference type="eggNOG" id="COG4758">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102484_4_1_11"/>
    <dbReference type="OrthoDB" id="1687355at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012551">
        <property type="entry name" value="DUF1707"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08044">
        <property type="entry name" value="DUF1707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="162" mass="18349" checksum="7E7DB67B3D03254B" modified="2010-04-20" version="1">MPSQEPSIPAVPERDKRAGDTDRQRVADRLRAALDEGRLELSEYDERLQQTYAAKTYADLDTLLADIPGVAPVSASQVEPVADKNPHRYDDREHRRRKRRNRDKSIKQTWSGVGGATIFFTGLWAIQWIATGGSAPYFWPIWIFGFWALGAACATWAKLMKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBQ2</accession>
    <name>D3QBQ2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4-hydroxythreonine-4-phosphate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.262</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3264</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.262" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018505.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3264"/>
    <dbReference type="EnsemblBacteria" id="ADD42934">
        <property type="protein sequence ID" value="ADD42934"/>
        <property type="gene ID" value="Snas_3264"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3264"/>
    <dbReference type="eggNOG" id="COG1995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040168_1_0_11"/>
    <dbReference type="OMA" id="TAQVVMM"/>
    <dbReference type="OrthoDB" id="1414545at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050570">
        <property type="term" value="F:4-hydroxythreonine-4-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005255">
        <property type="entry name" value="PdxA_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30004">
        <property type="entry name" value="PTHR30004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04166">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00557">
        <property type="entry name" value="pdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="347" mass="36122" checksum="08E5978511789CE2" modified="2010-04-20" version="1">MNRPVLAVTLGDPVGIGPEITARTLAEVAGEDGHHGIAVGDAGALRRGAAAAGLDVDVRVVNDFSVAPAGPGTIDVYDIGVLGDAAPEWGTVDPRAGKAAVVAIEVATKAAMDQQVAGIVTGPINKEAIWASGSTHLGHTEMLGELTGVTRQDTMFVVRDPAADGHHLRIFFTTRHVALRKALDQLTRDRVGASIREALTALTVFGTEKPRLAVAAVNPHGGENGAFGDEEIVHIGPACEDARAEGLDVTGPVPADSVFHQGLSGRFDGVLSHYHDQGHIAAKTFDFNGTISVTVGLPILRTSVDHGTAFDIAGSGKADHGTMLSAYRAGVDYSPYVPRIRSTYGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU53</accession>
    <name>D3PU53_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribose-phosphate pyrophosphokinase</fullName>
            <shortName evidence="6">RPPK</shortName>
            <ecNumber evidence="6">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">5-phospho-D-ribosyl alpha-1-diphosphate</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl pyrophosphate synthase</fullName>
            <shortName evidence="6">P-Rib-PP synthase</shortName>
            <shortName evidence="6">PRPP synthase</shortName>
            <shortName evidence="6">PRPPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prs</name>
        <name evidence="8" type="ordered locus">Snas_1290</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 2 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016570.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1290"/>
    <dbReference type="EnsemblBacteria" id="ADD40999">
        <property type="protein sequence ID" value="ADD40999"/>
        <property type="gene ID" value="Snas_1290"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1290"/>
    <dbReference type="eggNOG" id="COG0462">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033546_2_0_11"/>
    <dbReference type="OMA" id="FGWARQD"/>
    <dbReference type="OrthoDB" id="1011035at2"/>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00583_B">
        <property type="entry name" value="RibP_PPkinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037515">
        <property type="entry name" value="Rib-P_diPkinase_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="7">
        <location>
            <begin position="12"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ribose-5-phosphate binding" evidence="6">
        <location>
            <begin position="234"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="45"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="104"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="35047" checksum="83C5DFFBA21068DD" modified="2010-04-20" version="1">MASISAANPKSLMLFSGRAFPELAEEIGEHLGVAPTPTDAYAFANGELFVRYRESVRGCDAFVVQSMSAPINRWLMETLIMVDALKRGSAKRITVVLPFYPYARQDKKHRGREPISARLVADLLKTAGADRILTVDLHTAQIQGFFDGPVDHLFAMETLASYMEQKYAGRPLAVVAPDAGRVRVAERWADRMGGVPLAFVHKSRDPLRPNEVVANRVVGDIEGRVCLLVDDMIDTGGTICRAAELLDSAGAADVVIGATHPIFSEPALERLDKAPASEVVVTNTLPLPPGASLEKLTVLSIAPLVAKAISEVFVDGSVTTLFGGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU65</accession>
    <name>D3PU65_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1302</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1302"/>
    <dbReference type="EnsemblBacteria" id="ADD41011">
        <property type="protein sequence ID" value="ADD41011"/>
        <property type="gene ID" value="Snas_1302"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1302"/>
    <dbReference type="eggNOG" id="COG1409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_459201_0_0_11"/>
    <dbReference type="OMA" id="FYLAETR"/>
    <dbReference type="OrthoDB" id="1242748at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="336"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="594" mass="62691" checksum="9C87EC104D0C411B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUD5</accession>
    <name>D3PUD5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3279</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the arylamine N-acetyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018519.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3279"/>
    <dbReference type="EnsemblBacteria" id="ADD42948">
        <property type="protein sequence ID" value="ADD42948"/>
        <property type="gene ID" value="Snas_3279"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3279"/>
    <dbReference type="eggNOG" id="COG2162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049918_1_0_11"/>
    <dbReference type="OMA" id="CKYSNTM"/>
    <dbReference type="OrthoDB" id="1687886at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001447">
        <property type="entry name" value="Arylamine_N-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11786">
        <property type="entry name" value="PTHR11786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00797">
        <property type="entry name" value="Acetyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01543">
        <property type="entry name" value="ANATRNSFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="283" mass="31587" checksum="5E155737E5BBBD59" modified="2010-04-20" version="1">MFEERQLDGYLRRIGVSGPLRADAESLRRIHRAHLATIPYENLDIQLGRTISLEPEALYRKVVESRRGGFCYEQNGTLALALRASGFTLTIVEGGVHREERGESAWGNHMLLLVEADGQRWIADAGLGDGFLEPLPLAEGEHRQGAFTHRLKRLDAETWRCFPDAHGSVGSFDFRLTPRKIEDFAGRCLELSTSPESSFVKVLTVQQPGEPCLARIRSRTFSTSGPTLSGGKTERFVTDRAEFETLLFDDFGLGRQTLNPSEVDTLWANATGQHETWLSTRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUU6</accession>
    <name>D3PUU6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5336</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5336"/>
    <dbReference type="EnsemblBacteria" id="ADD44970">
        <property type="protein sequence ID" value="ADD44970"/>
        <property type="gene ID" value="Snas_5336"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5336"/>
    <dbReference type="eggNOG" id="COG0609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013016_1_0_11"/>
    <dbReference type="OMA" id="FGCISIA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="347" mass="35213" checksum="A426C283E350B091" modified="2010-04-20" version="1">MSVTTSPKAAAAAPARSPVSRGTWLLALTGVLAVLCLLSIMLGSRAIGAGTVLDALAGDGDAQTVAIVWDVRIPRTAMALLVAAGLGMAGVLMQALTRNPLADPGLLGVTAGAAFAIVISVAFFGIASMLGFIWTGFGGALVAGLVVYLLGGVGRGGATPVKLAVAGVAVSALLSALTSGIVLTDTNALNRYRYWAAGSLAGQDTEVLLQIAPFLLVGMVVALSLASSLNSLALGDRVAKSLGRRVGLIRLTGAVVVTLLTGACVAVCGPIVFVGLIVPHVARAITGPDYRWMLGYTLVLAPILMLAADITGRVIARPTEVNVGVVLAFIGGPFFIALVRRRRLAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVE4</accession>
    <name>D3PVE4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016768.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1493"/>
    <dbReference type="EnsemblBacteria" id="ADD41197">
        <property type="protein sequence ID" value="ADD41197"/>
        <property type="gene ID" value="Snas_1493"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1493"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1106582_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="96"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="187"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="251" mass="27286" checksum="6663969E53759753" modified="2010-04-20" version="1">MNSAGIVAGGCYPDDPLGTKFPQPVDVEVDCGVWDLRASPELLTRAARSWREHGDSTSGAAEEIHRSCRELLDSEHLKGELAERFDTFQSELIAKLDQYEGVAERVAEQLDDASARLRTHQETLDGLRADILAKVPGHETNRGDSPPGPRPPVMSSGPVAPQVTGCVAPPPTHIVFQASSFEDLRAIEDAKAEAKQVRAEVDRVNDEVHKKLDEIARDLGMMGRDLVPQYGCGTAEVNNRDRRLPGGFTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVH1</accession>
    <name>D3PVH1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018656.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3421"/>
    <dbReference type="EnsemblBacteria" id="ADD43085">
        <property type="protein sequence ID" value="ADD43085"/>
        <property type="gene ID" value="Snas_3421"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3421"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_20_0_11"/>
    <dbReference type="OMA" id="YMAARVW"/>
    <dbReference type="OrthoDB" id="867226at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="7"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="388" mass="42271" checksum="3E9BCEADB706C488" modified="2010-04-20" version="1">MPTLPTETDVLIVGAGPVGLTLATALAQNGVQATLVDKLTDGANTSRAAVVHARTLEVLRDINISDDLVSRGVIVPHFEVRDRDRALLSVGFDKLPTPFPYTLMVPQNITEELLLTRLHTVGGEVHRPHEVTDITTRPDHVTATLTDGHQIRARYLIGCDGMHSTVREHSGIPFTGDTYAASFILADVHMTWSEPDDHVYLFFDPAGVMVVAPLPDGRHRIVATLDPAPEHPDTHDVQSLLDTRGPKAHPATIKDVVWSSRFRVHHRLADHYRADRILLAGDAAHVHSPAGGQGMNTGIQDAINLAEKLTAVLRDAAPSHTLDAYESERRPVAADVVAFTHRMTRIATLGNGPLRGLRNSALRALDFLPGVHHTLAMNLSELATTDRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVL5</accession>
    <name>D3PVL5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018700.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3465"/>
    <dbReference type="EnsemblBacteria" id="ADD43129">
        <property type="protein sequence ID" value="ADD43129"/>
        <property type="gene ID" value="Snas_3465"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3465"/>
    <dbReference type="eggNOG" id="COG0365">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_10_11"/>
    <dbReference type="OMA" id="TTFYDGP"/>
    <dbReference type="OrthoDB" id="141801at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="73"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="496"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="598" mass="65914" checksum="B47E1C667192AB59" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVN5</accession>
    <name>D3PVN5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lanthionine synthetase C family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3486"/>
    <dbReference type="EnsemblBacteria" id="ADD43149">
        <property type="protein sequence ID" value="ADD43149"/>
        <property type="gene ID" value="Snas_3486"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3486"/>
    <dbReference type="eggNOG" id="COG4403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009398_1_1_11"/>
    <dbReference type="OMA" id="HENLIAC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04792">
        <property type="entry name" value="LanM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025410">
        <property type="entry name" value="Lant_dehyd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017146">
        <property type="entry name" value="Lanti_2_LanM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13575">
        <property type="entry name" value="DUF4135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037228">
        <property type="entry name" value="Lant_mod_RumM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03897">
        <property type="entry name" value="lanti_2_LanM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4135" evidence="1">
        <location>
            <begin position="233"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1093" mass="119570" checksum="AA5B836619C8C2EA" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVU0</accession>
    <name>D3PVU0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5429</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5429"/>
    <dbReference type="EnsemblBacteria" id="ADD45061">
        <property type="protein sequence ID" value="ADD45061"/>
        <property type="gene ID" value="Snas_5429"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5429"/>
    <dbReference type="eggNOG" id="COG1896">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2525942_0_0_11"/>
    <dbReference type="OrthoDB" id="1877942at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="84" mass="9231" checksum="A123D9830A491E4D" modified="2010-04-20" version="1">MTVRLPPTRHGVWIATDVADHLVVTAVATPTCLLHDLAHVILGHTITHSEIPQTITYTSYQEKAATHLADHLAQTYPRLTAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVW1</accession>
    <name>D3PVW1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RHH_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5450"/>
    <dbReference type="EnsemblBacteria" id="ADD45082">
        <property type="protein sequence ID" value="ADD45082"/>
        <property type="gene ID" value="Snas_5450"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5450"/>
    <dbReference type="HOGENOM" id="CLU_2604357_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038733">
        <property type="entry name" value="Predicted_DNA_bind_prot_RHH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12651">
        <property type="entry name" value="RHH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_3" evidence="1">
        <location>
            <begin position="2"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="79" mass="8517" checksum="113A399896C5C6CB" modified="2010-04-20" version="1">MKRTTVYLPEADAQLLKQVARRTGKSEAQLIREGVAHVLQAAPTRARGLRMVVNSGDPQWANRVDGELASGFGADGLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW49</accession>
    <name>D3PW49_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FMN-dependent alpha-hydroxy acid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1502</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016777.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1502"/>
    <dbReference type="EnsemblBacteria" id="ADD41206">
        <property type="protein sequence ID" value="ADD41206"/>
        <property type="gene ID" value="Snas_1502"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1502"/>
    <dbReference type="eggNOG" id="COG1304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020639_6_1_11"/>
    <dbReference type="OMA" id="ENLSVPM"/>
    <dbReference type="OrthoDB" id="1186741at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02809">
        <property type="entry name" value="alpha_hydroxyacid_oxid_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="272"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="295"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="342" mass="35562" checksum="A552C4FE9AAB7368" modified="2010-04-20" version="1">MRWIDELPDRARELLPPPVTEYFGQGAAAGMSTAEAAAAWDALRLRPRVLRDVSTVSTATTVLGQPVDTPVLVAPTTLQRLAHDEGESATARGAASAGSLLEVSTNAGTRFEVLGRQGAPWWVQAYIVRDRGFSVEVLKRAKAAGAGAVVLTVDTPEVGHKLQAGDSVWDLVTGDQLQANLDTDGLPDGALDKARDLTFADIGWLRETVGLPVVVKGVLRGDDARECVAAGAAAVQVSNHGGRQLDGAVSTARALPEIVRALDGTGAEVYVDGGLRRGSHILAALALGATAVFVGRPVLWALTVDGADGVRRLLADLTGELRHAMTLAGAASLDDLAPDLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWI2</accession>
    <name>D3PWI2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MDMPI_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018775.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3542"/>
    <dbReference type="EnsemblBacteria" id="ADD43204">
        <property type="protein sequence ID" value="ADD43204"/>
        <property type="gene ID" value="Snas_3542"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3542"/>
    <dbReference type="eggNOG" id="COG1576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051661_1_1_11"/>
    <dbReference type="OMA" id="DGHFGRT"/>
    <dbReference type="OrthoDB" id="1805421at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="1">
        <location>
            <begin position="9"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="157" mass="17225" checksum="59485B2E5DA6CA7D" modified="2010-04-20" version="1">MDHAEAFKRASDGFAARIRAVRPDRWHSPSPCAPWTARDVVAHVINEQRRMLSTVRGVDPEPVHGVGIAEMGTIPELAADADLAAAWDQVGSGHTWDLARATGGDERLDPDVVRQVHEALKPLEEFFRQPWAFGPKVDAPPGADAQTEFLCFVGRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWL0</accession>
    <name>D3PWL0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018803.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3570"/>
    <dbReference type="EnsemblBacteria" id="ADD43232">
        <property type="protein sequence ID" value="ADD43232"/>
        <property type="gene ID" value="Snas_3570"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3570"/>
    <dbReference type="eggNOG" id="ENOG5033Z0Q">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_394267_0_0_11"/>
    <dbReference type="OrthoDB" id="2076761at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="403"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="465"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="502"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="535"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="559"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="592"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="638"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="673" mass="70379" checksum="FBC0E6B4CB6E9D9F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWX4</accession>
    <name>D3PWX4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Abortive infection protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020769.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5567"/>
    <dbReference type="EnsemblBacteria" id="ADD45198">
        <property type="protein sequence ID" value="ADD45198"/>
        <property type="gene ID" value="Snas_5567"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5567"/>
    <dbReference type="eggNOG" id="COG1266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086373_0_0_11"/>
    <dbReference type="OrthoDB" id="922757at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="262" mass="28998" checksum="BC1F1DB13A519120" modified="2010-04-20" version="1">MSRTETPRSAGVVNRLLSSRHSLPLTIALHLLPGVPIVAAYLGIASPVVDMLGLPPYLGWVIAMCLGLAPVQLGLLVFLGRRRTGRFSLREVVLYRDRPTKRGRLIGLVLALFVGVFVASFLLAPIDTAVHETLFFWIPFENTGGGGGFVTGYPRQTVIVTLAVCVVLTGVLLPIVEELYFRGFLLPRISHLGRWAPVLNATLFSLYHFWTPWQLVSRIGYFLPTVWATWRKKDLRISIWVHCAANSVLQLAVLTAIILGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX57</accession>
    <name>D3PX57_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5651</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020852.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5651"/>
    <dbReference type="EnsemblBacteria" id="ADD45281">
        <property type="protein sequence ID" value="ADD45281"/>
        <property type="gene ID" value="Snas_5651"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5651"/>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_5_11"/>
    <dbReference type="OMA" id="DNHELYI"/>
    <dbReference type="OrthoDB" id="1911275at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="14"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="219" mass="24220" checksum="3DB82E2C86195A9D" modified="2010-04-20" version="1">MSEVGDRVAPARRRGLADEVADRVREAIFVGRYPPGAQLREVELSAALEVSRGPVREALLRLEREGLVRSSWHRGATVTDLSADDIAELDSLRGALEDLAVAEVIARADDAELAAIGKLADAMERAVDEHELVRRDIEFHDAVFAATGHGRLLEAWRSIRCQVHLFLLTRVNRSVEGYLSGVPAEHRELVAVLRARDGQRALELFAAHRRRAVEVLTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXA1</accession>
    <name>D3PXA1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenazine biosynthesis protein PhzF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016935.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41364">
        <property type="protein sequence ID" value="ADD41364"/>
        <property type="gene ID" value="Snas_1662"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1662"/>
    <dbReference type="eggNOG" id="COG0384">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048756_0_2_11"/>
    <dbReference type="OMA" id="FHVRDPF"/>
    <dbReference type="OrthoDB" id="1468060at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="278" mass="29300" checksum="F870ECCFA3EA7AD0" modified="2010-04-20" version="1">MEILRYTAFSTDPAGGNRAGVVLDATGADDAAMLATAAEIGYSETAFVFPRPDGELDVKYFSPLAEVPFCGHATIATAVAYAERHGVGELTLHTRAGVITVSTDRDTDGSIVATLVSAPPSSEELPSDNLDQILSALGWDASDLDPQLPPRVAYAGARHPIIAAATRQRLSDLDYDFEALSKLMEREDWTTVDLVWRESDTVFHARNPFPPGGIVEDPVTGAAAAAFGGYLRELKLVDTPASLTVYQGQDLGRPGTITVTVPAEPDTGIGVTGTAVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXF0</accession>
    <name>D3PXF0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016984.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1714"/>
    <dbReference type="EnsemblBacteria" id="ADD41413">
        <property type="protein sequence ID" value="ADD41413"/>
        <property type="gene ID" value="Snas_1714"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1714"/>
    <dbReference type="eggNOG" id="COG3878">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092069_0_0_11"/>
    <dbReference type="OMA" id="ALYWLID"/>
    <dbReference type="OrthoDB" id="1878535at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015315">
        <property type="entry name" value="DUF1963"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035948">
        <property type="entry name" value="YwqG-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09234">
        <property type="entry name" value="DUF1963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103032">
        <property type="entry name" value="SSF103032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="261" mass="27957" checksum="AFB1313CE1DBF61D" modified="2010-04-20" version="1">MTDNLVDIGRSLLPAPIADRWLSLLRPGIRLKHATGADPVVGWLGGDPALPPDEPWPTDAAGAPLHHLMSLDLAILLRIDFDLPGDGLLEFFCDGPSGSLGRVRYFPAASAAVPRAAPAGTEQPFTRVALTSVIELTSPDYDHSYLHAIEADLGDDDTGVLDNDAFWDLVDKTPIPSHRVGGYGRDIQYAADFAPSSTPVEVPGPDGPRTDTTLPLLLAQIDTDSAAGIGWGDVGTSLWTITREDLAARRFDDVDFHWSCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXF6</accession>
    <name>D3PXF6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2,5-didehydrogluconate reductase</fullName>
            <ecNumber evidence="5">1.1.1.274</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1721</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.274" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016990.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1721"/>
    <dbReference type="EnsemblBacteria" id="ADD41419">
        <property type="protein sequence ID" value="ADD41419"/>
        <property type="gene ID" value="Snas_1721"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1721"/>
    <dbReference type="eggNOG" id="COG0656">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_0_1_11"/>
    <dbReference type="OMA" id="WRHPDEP"/>
    <dbReference type="OrthoDB" id="1035565at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050580">
        <property type="term" value="F:2,5-didehydrogluconate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="PTHR43827"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="4">
        <location>
            <begin position="19"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="3">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="276" mass="30369" checksum="714761A17C1BA9A5" modified="2010-04-20" version="1">MTSAPNITLNNGVEMPQLGLGVWRASDDEARRSCVVAIDNGYRSIDTASLYKNEEGVGRAVAESGVPRGDLFITTKLWNNDQGFDAALKAFDASLDRLGMDYVDLYLIHWPAPGQDLYVETWKALERVYADKRARAIGVSNFHVSHLERLAAECEIVPALNQIELHPYLPQAELRGYHAAHGIHTEAWRPIGQGGELLVEPGLMRVAAKHGKSVAQVVLRWHIQLGNVVIPKSVTPSRIVENIDVFDFSLDEADMAAVAALESGRRMGMDPDEFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXJ6</accession>
    <name>D3PXJ6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sodium/hydrogen exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3668</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018897.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3668"/>
    <dbReference type="EnsemblBacteria" id="ADD43326">
        <property type="protein sequence ID" value="ADD43326"/>
        <property type="gene ID" value="Snas_3668"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3668"/>
    <dbReference type="eggNOG" id="COG0025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008635_6_2_11"/>
    <dbReference type="OMA" id="FARDGWF"/>
    <dbReference type="OrthoDB" id="1194802at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="221"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="9"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="408" mass="43170" checksum="3F4D13C0E22CB2EF" modified="2010-04-20" version="1">MPLLLSFALLLLAAVLLSSLAHRTILSTAVLFLAGGFVLGDGVLGVISLTPADDSVKILAELALFAVLFTDGMKVGWPQLRRAWRLPGRALGWGMPLTLAVTAVAAHFIVGLDWPESLLLGAVLAPTDPVFASALVGNEKVPHRLRHLLNVESGVNDGIALPFVMVFLAVCAGSGDLGVGELGLELLLGLVIGVAVPWLALRLERLRFFAASTQYEPLNAVAIGIVVLAVSQAVHGNLFIAAFTAGITVATFGPRQRHAFEHFGELGAELLKLAALLVFGALISPVFLAEIGVAGWVFVVVAIVVARPVALWVSFLRAGLNLREQAAAMWFGPKGFASVVYGLIVLESGIAAADVLFHLIAGAIVVSILLHSSTDVVVARWFDDSDETPAWHRHVRRLRGRKGANGET</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXR2</accession>
    <name>D3PXR2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Orn/DAP/Arg decarboxylase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Orn/Lys/Arg decarboxylase class-II family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018963.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3735"/>
    <dbReference type="EnsemblBacteria" id="ADD43392">
        <property type="protein sequence ID" value="ADD43392"/>
        <property type="gene ID" value="Snas_3735"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3735"/>
    <dbReference type="eggNOG" id="COG0019">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026444_0_3_11"/>
    <dbReference type="OMA" id="NISHHDF"/>
    <dbReference type="OrthoDB" id="861683at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006596">
        <property type="term" value="P:polyamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002433">
        <property type="entry name" value="Orn_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01182">
        <property type="entry name" value="ORNDCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="2">
        <location>
            <begin position="23"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="3">
        <location>
            <begin position="28"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="388" mass="41662" checksum="F465DE15281B24AC" modified="2010-04-20" version="1">MTPAIPTRVAAAIDTLSHPVCAYVYDLAALSERIAAVKAALPPQTRLFYAMKANSRPELVARAAQYCDGIEIASPGELATAIAAGARHLIYGGPSKTDAALTAALSCGTPVTVNVEGLHELRRLDRLARQHGTVAEIALRVNRATETPGGTHRMTGTPTPFGIDAAHLDDAVDLARRLPGVRLTGLHLHAVSNNLDAAAHARFVAEALEYAADTATRHGLTWETVNLGGGIGVDPAGGSEFDLADFAARLTRPAVTTIFELGRYLAAETGWYATEVTDIKTTHGRTFAVVRGGTHHFRLPAAWGYDHPAAVHPVDEWPYPWQRPEARDTTVDVTGELCTPRDVLCRDLPVSRLRVGDVLVFGRTGAYGWDISHHDFLSHPHPDTVVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY62</accession>
    <name>D3PY62_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45391">
        <property type="protein sequence ID" value="ADD45391"/>
        <property type="gene ID" value="Snas_5761"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5761"/>
    <dbReference type="HOGENOM" id="CLU_131550_3_3_11"/>
    <dbReference type="OMA" id="GSACHAN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="1">
        <location>
            <begin position="10"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="71" mass="7947" checksum="82A238A193DA4CC3" modified="2010-04-20" version="1">MYRTEFRHPVWRKAARSFANNECVEVAQLSARTVGLRDSKLSARRDCPVLLADAAGWEGFTEQIKSGTFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYJ0</accession>
    <name>D3PYJ0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="3">1.2.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_1861</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + L-glutamate + NADH</text>
            <dbReference type="Rhea" id="RHEA:30235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="1.2.1.88"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.88" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017128.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1861"/>
    <dbReference type="EnsemblBacteria" id="ADD41557">
        <property type="protein sequence ID" value="ADD41557"/>
        <property type="gene ID" value="Snas_1861"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1861"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_4_1_11"/>
    <dbReference type="OMA" id="WKPSPFA"/>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="UniPathway" id="UPA00261">
        <property type="reaction ID" value="UER00374"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:1-pyrroline-5-carboxylate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:proline catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005931">
        <property type="entry name" value="P5CDH/ALDH4A1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01236">
        <property type="entry name" value="D1pyr5carbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="54"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD41557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="542" mass="58114" checksum="0A724EA8BC6F8332" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYQ2</accession>
    <name>D3PYQ2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019056.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3829"/>
    <dbReference type="EnsemblBacteria" id="ADD43485">
        <property type="protein sequence ID" value="ADD43485"/>
        <property type="gene ID" value="Snas_3829"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3829"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090621_0_0_11"/>
    <dbReference type="OMA" id="EATHRIY"/>
    <dbReference type="OrthoDB" id="1270792at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013653">
        <property type="entry name" value="FR47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08445">
        <property type="entry name" value="FR47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="115"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="249" mass="27284" checksum="7687881C019F5F20" modified="2010-04-20" version="1">MSSFPVLKGREAILAAYRAEPFVSCFLADNAEGVVRDDAVAWFREFNGRSVLMGDGPVRATARLVAELAPHWRPDRLTVPQEVFEQLPGELRSAKPGRWHWFFTRSAPPTHPAESRVRWCTESDFDAITALLDVAFPDASSRPDPAVPHRRWFGATDANGSIVACGIAQVGDGIGPMLGSIAVHPDARRQGLGSAITSWVTRRLLDEGNAMVALGSYAGEEATHRIYRRLGYRDTRVLASGRLEPSPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYX2</accession>
    <name>D3PYX2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_3900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3900"/>
    <dbReference type="EnsemblBacteria" id="ADD43555">
        <property type="protein sequence ID" value="ADD43555"/>
        <property type="gene ID" value="Snas_3900"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3900"/>
    <dbReference type="eggNOG" id="COG0180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029244_0_1_11"/>
    <dbReference type="OMA" id="LGHYFGT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD43555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="343" mass="37417" checksum="F01C7DFF263434D1" modified="2010-04-20" version="1">MTTIATNQLTVPDEIRSRPGTARMLTGDRPTGKLHIGHYFGSLRNRVRLQNQGVDSLVVIADYQVLTDRDIAADLSGHIHEIVLDYLAAGISPQRSTIFTHSAVPALNQLLLPFLSLVSTAELDRNPTVKEEIAAARRASVSGLIYTYPAHQAADILFCDATVVPVGDDQLPHLELTRTIARRFNDRYGKVFTVPKPLLSPAPRLLGVDGRTKMSKSRGNAIALSATADETARLIKSAVTDADRHINYDPANRPGVSNLLLLIGLCTGQEPEQVAESLSGAADLKRTCTEAVNEFFAPLRRRRRELAADPAQVGRIITEGNTRARTIADDTLDRVRRAMGTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZC5</accession>
    <name>D3PZC5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1903</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017170.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1903"/>
    <dbReference type="EnsemblBacteria" id="ADD41599">
        <property type="protein sequence ID" value="ADD41599"/>
        <property type="gene ID" value="Snas_1903"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1903"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="THRETEV"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="151"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="225" mass="24141" checksum="2F5467184BDF4479" modified="2010-04-20" version="1">MSQPIRVLVADDHLVVRTGFAELLGTQPDFSVVGIASDGAEAVMACRTATPDVVLMDVRMPNMDGIEATRRIAATSEATPRVIILTTFDLDEYVYDALRAGASGFLLKDVTAERLFDAVRVVAAGEALLAPTVTRRLIGEFVQSKQPRPVADARLASLTPRETEVLRLVAEGLSNPELAARLTVSEETVKTHVSRVLHKLGLRDRTQAVVAAYESGLVVPGGRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZG0</accession>
    <name>D3PZG0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017205.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1938"/>
    <dbReference type="EnsemblBacteria" id="ADD41634">
        <property type="protein sequence ID" value="ADD41634"/>
        <property type="gene ID" value="Snas_1938"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1938"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_27_0_11"/>
    <dbReference type="OMA" id="AAEHFFC"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="226" mass="24446" checksum="73A3B0C9E24F3EA7" modified="2010-04-20" version="1">MATETAPSSRPVGGRADKRESIIRGAMAVFAEEGYTRASIDAIAKRAGVSTRTIYNHFRDKPELFHVTIMTSTNGVGDAISALIERHFHKVTDVEADLNAFGFDLVTSKGEFSAHFAMMQQVKTEWAHVPAEAARLWREAGPRRVNNELAAKLSELDAKGLLRVENPQQAAKHLQTLVWGSLPIDFDLAATPESEIAAHVASGVRVFLYGYAAPSELPVASGSASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZN7</accession>
    <name>D3PZN7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019145.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3919"/>
    <dbReference type="EnsemblBacteria" id="ADD43574">
        <property type="protein sequence ID" value="ADD43574"/>
        <property type="gene ID" value="Snas_3919"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3919"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_2_0_11"/>
    <dbReference type="OMA" id="CPSRGTL"/>
    <dbReference type="OrthoDB" id="2057904at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="22"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="131" mass="14535" checksum="12EA6335F79F34A9" modified="2010-04-20" version="1">MSASPDTGPSDELVADVFDRKCPSRGVMEHVGSKWGILSLTALDQRPMRFNALRRTVTGVSEKMLSQTLHTLERDGFVHREVHTSIPPHVEYSVTPLGHRVAVKLAELIDLLEDTLDESVAAQEAYDKRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZS7</accession>
    <name>D3PZS7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43614">
        <property type="protein sequence ID" value="ADD43614"/>
        <property type="gene ID" value="Snas_3962"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3962"/>
    <dbReference type="HOGENOM" id="CLU_2994513_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="57" mass="6418" checksum="FC36C0E82E366370" modified="2010-04-20" version="1">MSCEYPVVDSMMRIVDSGQSVSIDEMATEVRTHGADSRPSRRDDFPRDLRELTTEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q012</accession>
    <name>D3Q012_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_C39_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5913</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021112.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5913"/>
    <dbReference type="EnsemblBacteria" id="ADD45541">
        <property type="protein sequence ID" value="ADD45541"/>
        <property type="gene ID" value="Snas_5913"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5913"/>
    <dbReference type="eggNOG" id="COG3179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099864_0_0_11"/>
    <dbReference type="OMA" id="IEMPNDP"/>
    <dbReference type="OrthoDB" id="1441395at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039564">
        <property type="entry name" value="Peptidase_C39-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13529">
        <property type="entry name" value="Peptidase_C39_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049410" description="Peptidase_C39_2 domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_C39_2" evidence="2">
        <location>
            <begin position="78"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="243" mass="25919" checksum="83D0F497C596E633" modified="2010-04-20" version="1">MKRRTMLTGAIGLTVAGGLMTAGTALASTPTTNGVSPVKPAPAGSNGVQVATKVVSGRNSKFPVLRTERVDTKVEKVLEVDYQVQETGYWCGPAATRIALSARVEVPNQATLAAELGTHEGGTDHISQVTTVMNNRIDTGTYYTIEMPNDPPTQGQVDKLWADVTADIDNGFAIVANIVAPPGNQPPGYPPDQTIYHYFSVIGYNSDQNTVLIGDSASFSGYQIYWLTFHQLSTLIPPKGYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q056</accession>
    <name>D3Q056_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5958"/>
    <dbReference type="EnsemblBacteria" id="ADD45585">
        <property type="protein sequence ID" value="ADD45585"/>
        <property type="gene ID" value="Snas_5958"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5958"/>
    <dbReference type="eggNOG" id="COG5395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078522_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018750">
        <property type="entry name" value="DUF2306_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10067">
        <property type="entry name" value="DUF2306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="238" mass="26941" checksum="768277717A511DE9" modified="2010-04-20" version="1">MDQPTVTETPTAPATAKVPWWRRPWIVPLWAISALFLVWRVPDYVGYKDPGALVEMSDYQHFLIVSGHIMLGGVSLICCCMQLWPWLRTNHPKVHRVTGRVYVLVVLPASVLAFFTSFMSITTPPSGQVGNGILATLWLLTTLIGFRHVRNGRYADHRRWMIRSFALCFSIVVNRLFIGVYAVGFSPLLDSFYGGSVDRLATDAAVASIWSSWVATLVFAEWWMTRRRKPRKRVATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0B3</accession>
    <name>D3Q0B3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015348.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0055"/>
    <dbReference type="EnsemblBacteria" id="ADD39777">
        <property type="protein sequence ID" value="ADD39777"/>
        <property type="gene ID" value="Snas_0055"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0055"/>
    <dbReference type="eggNOG" id="ENOG50321GG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_816167_0_0_11"/>
    <dbReference type="OMA" id="DACAPRI"/>
    <dbReference type="OrthoDB" id="1418965at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="331" mass="35350" checksum="F090BCEBEF40DF96" modified="2010-04-20" version="1">MNRREGRRTRWLAVLLLLVLSPVCAEYIQAYDDSTGNPVALLGALLVFVPLYGAPAVLIRELARRFDVRWPGILALTTGFGILQAGVIDQSMFDTGYRGIDYWDDMIMPTWIEPLGISVNASLAFVLGHAIWSFGVPIALSEAISGRYSRTPWLRWPGLSVLVVLYLAAAALIMVGEDSGGASSGQLVGALAVTAALALFAFTLGRRRRDRRDRRVPAPLLVFAVAAPVSFGFNMLGYSISDTVIVVGLLVAVAAAVTYLSGSRAWTGRHVAALASGTLLGRVGIGFLTDPLGDVSAVAHAGHSVFFLLMALGLWLLADRRSRATPATDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0B8</accession>
    <name>D3Q0B8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclase/dehydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015353.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0060"/>
    <dbReference type="EnsemblBacteria" id="ADD39782">
        <property type="protein sequence ID" value="ADD39782"/>
        <property type="gene ID" value="Snas_0060"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0060"/>
    <dbReference type="eggNOG" id="COG4891">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069867_4_0_11"/>
    <dbReference type="OMA" id="RYPEWNP"/>
    <dbReference type="OrthoDB" id="1719670at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="20273" checksum="DE9C28A3565994F1" modified="2010-04-20" version="1">MPPSDPPDPPPKPRKLRNRILIGLSVLVVLLAGYTAWANLHVYTLTASIDIDAPPDKVWEVLVDRESYPDWNPFLVSSKGGLKEGGTITNLMRGADGTETEFTPTVLVVEPGKELRWIGKLSPGLLFDGEHSFRLIKRGSGTRLIQSEDFTGALVPPMQSWLDGDTLPQFKAMNKALKKRAEAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0C9</accession>
    <name>D3Q0C9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0071</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015364.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0071"/>
    <dbReference type="EnsemblBacteria" id="ADD39793">
        <property type="protein sequence ID" value="ADD39793"/>
        <property type="gene ID" value="Snas_0071"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0071"/>
    <dbReference type="eggNOG" id="COG0247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005304_1_0_11"/>
    <dbReference type="OMA" id="EMHRHKE"/>
    <dbReference type="OrthoDB" id="1951488at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="311"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="394"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD39793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="727" mass="79681" checksum="C693285D27F18D65" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0D4</accession>
    <name>D3Q0D4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015369.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0076"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD39798">
        <property type="protein sequence ID" value="ADD39798"/>
        <property type="gene ID" value="Snas_0076"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0076"/>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_9_0_11"/>
    <dbReference type="OMA" id="MVNTDAV"/>
    <dbReference type="OrthoDB" id="1064289at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04188">
        <property type="entry name" value="DPG_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035518">
        <property type="entry name" value="DPG_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="33"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="271" mass="29624" checksum="55C38223F83B6DC0" modified="2010-04-20" version="1">MNAVNQPRPSALATLARSTAAPARTAPAVVDQSVIIPVYNESDRLAATLAEVRAHLNGAGGAWELIVVDDGSRDDSAAIAARFAAGEPRIRLLRTPRNRGKGHAVRHGVLASRGRRVLYCDADLATPIGELDRLHAKLDAGFAGAIGSRVGPHADIRQRQPLPRVLLGRLGNRLIRLAAVPGVGDTQCGFKLFDGDKARRAFTLTRVDGWAFDVEVLYLFARGDWPVAEVPVRWSHRAGSKVRMRDYPATLAELLRMRWRHRGAPPRVRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0E0</accession>
    <name>D3Q0E0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nicotinate-nucleotide diphosphorylase (carboxylating)</fullName>
            <ecNumber evidence="4">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Snas_0082</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the NadC/ModD family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015375.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0082"/>
    <dbReference type="EnsemblBacteria" id="ADD39804">
        <property type="protein sequence ID" value="ADD39804"/>
        <property type="gene ID" value="Snas_0082"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0082"/>
    <dbReference type="eggNOG" id="COG0157">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039622_0_1_11"/>
    <dbReference type="OMA" id="DMIMLKD"/>
    <dbReference type="OrthoDB" id="1718114at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="11">
        <location>
            <begin position="34"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="10">
        <location>
            <begin position="123"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD39804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="291" mass="30976" checksum="742348BE7728BD17" modified="2010-04-20" version="1">MTTVDERLTAQGLDPDEVNAIIDRALAEDLGPNRSDPTSEAIFPLTVTGTADLVARESGVVAGLAVAEAVFKHFDPNVAFTHLVDDGARVYAGDRLATVAGPVRYLLMAERTVLNLLCRMSGIATHTREWTRVLDGTKVTVLDTRKTTPGLRTLDKYAVRAAGGGNKRMGLYDVAMIKDNHKFAAGSVTAAFEAVRAARPDIAIQVEVDTLDEAREAVAAGATFLLCDNMSPAQLREVVAAVGPDVQLEATGNITLTIAEKYADTGVDYISSGALTHSSPILDIALDIRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0G2</accession>
    <name>D3Q0G2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2002</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017269.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2002"/>
    <dbReference type="EnsemblBacteria" id="ADD41698">
        <property type="protein sequence ID" value="ADD41698"/>
        <property type="gene ID" value="Snas_2002"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2002"/>
    <dbReference type="eggNOG" id="COG0122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1037271_0_0_11"/>
    <dbReference type="OMA" id="RIGPWTA"/>
    <dbReference type="OrthoDB" id="1781735at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="277" mass="30410" checksum="54A794C528A1AF20" modified="2010-04-20" version="1">MTAQCHEIVRHADLVMTEHPAWRATSDGYVRIFDLIDSGRIMVIVSDGHAKAQRQLPGEANLVCDLYTLQADTCQDASELARALTSQGTVGRFRTTNLWEALGTAVCFRQDVPVPTHAYHFLCLMYGEQVPLPRGGYYLMFPTPDIIVELSPSHLASCGIGAVADVLIAAADVYARCSESWNASSPGVLVSALQTITGVDSEVAATAIADWSGDFAFYTYANTRMRTLAATAAPKTTWPRTQTEFSRRWRHLANGELSTLTALMLAWGWRQHRSAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0H5</accession>
    <name>D3Q0H5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GH18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2016</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017282.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2016"/>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41711">
        <property type="protein sequence ID" value="ADD41711"/>
        <property type="gene ID" value="Snas_2016"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2016"/>
    <dbReference type="eggNOG" id="COG3469">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060983_1_0_11"/>
    <dbReference type="OMA" id="IAWYNAQ"/>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048521" description="GH18 domain-containing protein" evidence="5">
        <location>
            <begin position="30"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="6">
        <location>
            <begin position="37"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="313" mass="33765" checksum="08B895DC087C1567" modified="2010-04-20" version="1">MRLRRRTIAVGSVVAILGAVGLTAATAQAEPTESAGQRLVVYYQTQYHGDAQEYVSPIPLADNGATDIMVAAIHLNDASSQNPVTLNDHAPEDPRYDRMWEELKTVQDKGKNVLGMVGGAAPGTFQRLDTDFDTYYPLLRDTIKKYGLDGVDLDVEEDMSLAGIERVIDALKADFGADFLITLAPVATALSGGGNISGFNYDDLYASRGEDIDWFNAQFYCGWGLLDDTGDYDAVIDHGVVPANKVVAGTITNPANCGSGYVELDTLKSTIGTLKQKYPDFGGIMGWEYFNSLPGDTAEPWLWAKEVSAALSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0L8</accession>
    <name>D3Q0L8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="10">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Snas_2060</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 10">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:54452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:23624"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the dus family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2060"/>
    <dbReference type="EnsemblBacteria" id="ADD41754">
        <property type="protein sequence ID" value="ADD41754"/>
        <property type="gene ID" value="Snas_2060"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2060"/>
    <dbReference type="eggNOG" id="COG0042">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013299_0_0_11"/>
    <dbReference type="OMA" id="RPWLFAD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024036">
        <property type="entry name" value="tRNA-dHydroUridine_Synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004652">
        <property type="entry name" value="tRNA_dU_NifR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00737">
        <property type="entry name" value="nifR3_yhdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 10" id="KW-0288">FMN</keyword>
    <keyword evidence="9 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Dus" evidence="13">
        <location>
            <begin position="18"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="352"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD41754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="394" mass="42447" checksum="5FEC978CD5451525" modified="2010-04-20" version="1">MSTSLTLGGHVVDPPVVLAPMAGITNVAFRRLCAEQGAGIYTCEMVMTRALLERNPKTTRMIAFGPGERPRSLQLYGVDPVTVRKAVEMIVDEDLADHIDMNFGCSVPKVTRKGGGSAIPYKRNLFGQIVRSAVEAAGDIPVTVKMRKGIDDELLTFVDAGRVAQDAGAAWVALHARTAAQRYSGTADWDAITELKRALDIPVLGNGDIWEATDALRMVEETGCDGVVVGRGCLGRPWLFADLAAAFAGSSHRVMPSLGEVAAIMRRHAALLVDWYSSAGAPVEEGKSLRPEKRRKISAEEHGVTDFRKHVAWYLKGFSVGGELRRSLAMSSSLDELAELLSHLDADQPFPAEVLGRPRGRTNSPAKVQLPEGWLDDPDDGTVPTEADVEHSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0R1</accession>
    <name>D3Q0R1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Propeptide PepSY amd peptidase M4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2103</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017368.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2103"/>
    <dbReference type="EnsemblBacteria" id="ADD41797">
        <property type="protein sequence ID" value="ADD41797"/>
        <property type="gene ID" value="Snas_2103"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2103"/>
    <dbReference type="eggNOG" id="COG3212">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1093764_0_0_11"/>
    <dbReference type="OMA" id="GTWHSVR"/>
    <dbReference type="OrthoDB" id="1593449at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025711">
        <property type="entry name" value="PepSY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03413">
        <property type="entry name" value="PepSY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048532" evidence="2">
        <location>
            <begin position="36"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="PepSY" evidence="3">
        <location>
            <begin position="74"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="PepSY" evidence="3">
        <location>
            <begin position="159"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="254" mass="26766" checksum="9782292675E0B792" modified="2010-04-20" version="1">MSEKLLNRRNRWIIAGATGVLLVGGSAALATTAFADDGDANETGAQVADDDDNDGDDDGTDDDGDDATPSTKPKISLADATATASDEVSKGILTSIELEGTNDAPFWRVDFITSDGTEHEVTIDAAKGDVTDHNKETDDDGDKEDWTEAKAANDQVKTTPEDAATAALDKAGKGNVTSIELDDDANNPQWEVDVTTDDGKHKDVTVDAVTGKATDVYTDDDDNDSDDANDDDSDQDDDNDQGDDDANDNDGDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Y8</accession>
    <name>D3Q0Y8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019309.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43738">
        <property type="protein sequence ID" value="ADD43738"/>
        <property type="gene ID" value="Snas_4086"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4086"/>
    <dbReference type="eggNOG" id="COG3021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1022253_0_0_11"/>
    <dbReference type="OMA" id="INTHYIA"/>
    <dbReference type="OrthoDB" id="1364512at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049435" evidence="1">
        <location>
            <begin position="32"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="273" mass="30711" checksum="D46355D2DEC56A44" modified="2010-04-20" version="1">MSRMFSRRNVLILGAGAAAAGALGVTGYAQADVAATASEWIRLPIITANIGRKRLSKREAAIRAVRSGDRGHRPLVGWQEIGEGDSGEKAMIAKHFDEHYKNPFLRDGRAYRVPFSIPNHWTVVSTKRNFVHRGIEGWSPERWINEVVLRHVKYTGIEFALINSHYIANAYNGDRKPSLQDEWRKHRKLHGNRVLAHHAAGRPVIWTGDVNRPDYTTASGRSAEKKAFSKGIDRINWLPAGDKIQIQLQGTRTVDMDVDSHNARVAIFRIRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q109</accession>
    <name>D3Q109_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019330.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4108"/>
    <dbReference type="EnsemblBacteria" id="ADD43759">
        <property type="protein sequence ID" value="ADD43759"/>
        <property type="gene ID" value="Snas_4108"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4108"/>
    <dbReference type="eggNOG" id="COG3383">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153062_2_0_11"/>
    <dbReference type="OMA" id="RPNQRAC"/>
    <dbReference type="OrthoDB" id="1885467at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042204">
        <property type="entry name" value="2Fe-2S-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="85" mass="9012" checksum="7093BB12650F22D9" modified="2010-04-20" version="1">MRVTVDGVEVEAASGQTVAAVLLRLGRVSWRTTREAGRPRGIFCGIGVCHDCLVVVNGVPDVRACQRLVGDGDDVRTQHGAELPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q167</accession>
    <name>D3Q167_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021218.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6022"/>
    <dbReference type="TCDB" id="1.E.34.1.6">
        <property type="family name" value="the putative actinobacterial holin-x (hol-x) family"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45647">
        <property type="protein sequence ID" value="ADD45647"/>
        <property type="gene ID" value="Snas_6022"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6022"/>
    <dbReference type="eggNOG" id="ENOG5032TF3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106273_5_1_11"/>
    <dbReference type="OMA" id="THVPPVH"/>
    <dbReference type="OrthoDB" id="1962250at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009937">
        <property type="entry name" value="Phage_holin_3_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07332">
        <property type="entry name" value="Phage_holin_3_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="156" mass="16786" checksum="57813BC6DFC6DE8F" modified="2010-04-20" version="1">MSSYRIDTTADTRPHAEPDGKQPSIGSLVRDISQDMSRLMRQEVELAKAELRQEAGKAGKAAKMFGAAGFAGYMVAVLLTAAAVVGLSYLMAAIWAVLIMTGVWALIGLLAFLNGRKQLRTMSPVPRQTVDTLKEDAQWLRHPTGSEATSSRPGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q174</accession>
    <name>D3Q174_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_6029</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021225.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6029"/>
    <dbReference type="EnsemblBacteria" id="ADD45654">
        <property type="protein sequence ID" value="ADD45654"/>
        <property type="gene ID" value="Snas_6029"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6029"/>
    <dbReference type="eggNOG" id="COG4251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_3_11"/>
    <dbReference type="OMA" id="FDTMLAQ"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="88"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="149"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="367" mass="40192" checksum="38C7323BB3321AF9" modified="2010-04-20" version="1">MRRRLGLSVRLKLTLSYAGLLMLAGIFLLVLVWVFLLRYVPDRMIGPDEWIQPGPSRLELWEAFAPRAAQGFAFLMVFGLVGGWILAGRMLAPLTRITRATRLAGTGSLSHRIEMEGRKDEFRELADAFDTMLARLEAHVAEQQRFAANVSHELRTPLAVTQTILDVARNDRDGDNDELVDRLHAVNSRAIDLTEALLLLSRADRRSFNREPVDLSLVAEEATETLLPLAEKRGLAIETSGEATPAVGSHALLLQLTTNLVHNAIVHNLPADGTVWVTTRRGPEFVELTVDNTGRDLTPQLVSTLAEPFQRGSQRIRTDHAGVGLGLAIVKSIAEAHDGTLTLAPRPEGGLHVSVRLPAAPTPAPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1A4</accession>
    <name>D3Q1A4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrolase or acyltransferase (Alpha/beta hydrolase superfamily)-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021255.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6060"/>
    <dbReference type="EnsemblBacteria" id="ADD45684">
        <property type="protein sequence ID" value="ADD45684"/>
        <property type="gene ID" value="Snas_6060"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6060"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1084970_0_0_11"/>
    <dbReference type="OMA" id="RHITYDE"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="32"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="268" mass="29396" checksum="12CB0A14105703A0" modified="2010-04-20" version="1">MTNSNSKKSPWTGFVTVDDTALAVTDTGGDAPAVVYLNGAYSSQPAWRRVIAELGSGWRHITYDERARGKSRRSHDYSFEGTIRDLDAVLEARSVQRPLLVCWSFGAATAVHWAARNPSRVRGVVLVDGGFPHDWIDDAAKERTRQQFRKMRWALPLLAPFGMAARMSADQHAEINIEINEVFGALGAQYDQVTCPVRFVVATGASMGGTAEEMATMRASLDPVLARRPNIRVGATVPSNHVTVLRKDYRAVAEVVRETAAAAAKRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1G1</accession>
    <name>D3Q1G1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_6117</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021312.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6117"/>
    <dbReference type="EnsemblBacteria" id="ADD45741">
        <property type="protein sequence ID" value="ADD45741"/>
        <property type="gene ID" value="Snas_6117"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6117"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="EETWEVI"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="17"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="102"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="170" mass="19406" checksum="74FDA4AFBC8CA5AE" modified="2010-04-20" version="1">MTRHRSDFEEFAIACTPALLRSAYLLTGDQHLAEDLVQSALARTHRAWKRLEHSGNAHAYTRKIMYHLQVSWWRRRKVAESFTETPVETAFADSTHDVDLRLSLRAALFQLAPRQRAVIVLRYFEDRSVTQTAEILGCAEGTVKTQAFRALNKLRSVLPDLVELTNGELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1H7</accession>
    <name>D3Q1H7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0104</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0104"/>
    <dbReference type="EnsemblBacteria" id="ADD39825">
        <property type="protein sequence ID" value="ADD39825"/>
        <property type="gene ID" value="Snas_0104"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0104"/>
    <dbReference type="eggNOG" id="ENOG502ZTYE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_952867_0_0_11"/>
    <dbReference type="OMA" id="NQWRINA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="292" mass="32398" checksum="B2B2A47EAD1E0B59" modified="2010-04-20" version="1">MSRESHPLHPSFRLPETFTALVEFIMDGLDPADPDVWHYASWADKGGDLFSGDLSAGLLGKPVGDDPAELCGELLYTFQPLEILPFCWNGGDGLHYGWAVLAPELEGDDHPCVSFAPVDDHAVWLGDDTKQALENLLAGSMASWRERGREQGLDAPDTDERWGAVCRALDLRPDLDSGLISPGARSKRVLEPRVPEGWRYEATSDGIGVLAPQSAFAPETVQVDQPWDFEQWRVVARVYLDEGRPGSALAVLKSLSYYDRGTVELMGEAYRRLGRETHAERAELWLRLHATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1K5</accession>
    <name>D3Q1K5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015424.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD39853">
        <property type="protein sequence ID" value="ADD39853"/>
        <property type="gene ID" value="Snas_0132"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0132"/>
    <dbReference type="eggNOG" id="ENOG503287X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2048300_0_0_11"/>
    <dbReference type="OrthoDB" id="2203671at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049451" evidence="1">
        <location>
            <begin position="29"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="120" mass="12142" checksum="3514702A5A0BAE7D" modified="2010-04-20" version="1">MRKSIKALAVAAVAAGFGALALAGTAQAGPTGAEEMGMNPTGGGVSILSDICAGNWNGPVITGATANNTDTRDLCSGYNGSDDAQLKLGSNLCALNWDWNDAAKVGVINSVKDYRLCHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1M1</accession>
    <name>D3Q1M1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015440.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0149"/>
    <dbReference type="EnsemblBacteria" id="ADD39869">
        <property type="protein sequence ID" value="ADD39869"/>
        <property type="gene ID" value="Snas_0149"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0149"/>
    <dbReference type="eggNOG" id="COG2847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1085471_0_0_11"/>
    <dbReference type="OMA" id="NPREHAG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036182">
        <property type="entry name" value="PCuAC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110087">
        <property type="entry name" value="SSF110087"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049453" evidence="2">
        <location>
            <begin position="35"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="256" mass="25694" checksum="F44A4270A3D213EF" modified="2010-04-20" version="1">MPHAIPSKPLTRAALGVALAAASAFALTGCGAGQVTQTQDMVAAVPGTSATISKPSEGIKIALRDAYIEFAEDGYAAGEAAPLSIRIFNSGKKSDTLTKVEFPDSEAAGVTVAGESSGDASESPSDSESPSGDTSPSGDESPSGDESPSGDESPSGDSSASPSGDESPSGSESPSETASSKVDLKLPVNGKLLLAPDGDQYLELTGLKQELNAGDVVTITFVFAEAGEVEMDIPVAPPAEAAEREEPSEHGGEEGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1P2</accession>
    <name>D3Q1P2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0170</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015461.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0170"/>
    <dbReference type="EnsemblBacteria" id="ADD39890">
        <property type="protein sequence ID" value="ADD39890"/>
        <property type="gene ID" value="Snas_0170"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0170"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_11"/>
    <dbReference type="OMA" id="CEYTGAV"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03301">
        <property type="entry name" value="ABC_MalK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015855">
        <property type="entry name" value="ABC_transpr_MalK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="360" mass="38575" checksum="33A2F71001ED1E44" modified="2010-04-20" version="1">MADISIRNLSRTYSGQKAPATDDVSLDVADGEFMVFLGPSGCGKTTLLRMIAGLELPDAGSVAIGGKDVTYLAPRNRNLSMVFQSYAVFPHRRVRANIGFGLKMRGVAADEIARRVDRAADLLQLTDYLDRYPAQLSGGQRQRVAVARAIVVDADVLLMDEPLSNLDALLRLSFRAELKKIVAELGTTTVYVTHDQAEALSLGDRVAVMRSGRIVQQGGPIDVYDSPADTFVGGFLGSPPMNFLDGEVADGPKLRVGEQSLAVPSALASFAGQPVKLGVRAENITVSQSRDESAVPATVDVVEPVGASVLLTVTVDGQELKVQAPPTFRIDPGATAWLTFPADRLRFYDPESAMALETDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1X0</accession>
    <name>D3Q1X0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein-N(pi)-phosphohistidine--D-mannitol phosphotransferase</fullName>
            <ecNumber evidence="3">2.7.1.197</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Snas_2143</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-mannitol(out) + N(pros)-phospho-L-histidyl-[protein] = D-mannitol 1-phosphate(in) + L-histidyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:33363"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:16899"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:61381"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.1.197"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.1.197" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017408.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2143"/>
    <dbReference type="EnsemblBacteria" id="ADD41837">
        <property type="protein sequence ID" value="ADD41837"/>
        <property type="gene ID" value="Snas_2143"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2143"/>
    <dbReference type="eggNOG" id="COG2213">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028721_2_0_11"/>
    <dbReference type="OMA" id="GWAIKRF"/>
    <dbReference type="OrthoDB" id="554815at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022872">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05567">
        <property type="entry name" value="PTS_IIB_mannitol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036095">
        <property type="entry name" value="PTS_EIIB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013011">
        <property type="entry name" value="PTS_EIIB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003501">
        <property type="entry name" value="PTS_EIIB_2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029503">
        <property type="entry name" value="PTS_EIIB_mannitol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013014">
        <property type="entry name" value="PTS_EIIC_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02302">
        <property type="entry name" value="PTS_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52794">
        <property type="entry name" value="SSF52794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51099">
        <property type="entry name" value="PTS_EIIB_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51104">
        <property type="entry name" value="PTS_EIIC_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-2" evidence="15">
        <location>
            <begin position="20"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-2" evidence="14">
        <location>
            <begin position="398"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ADD41837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="490" mass="50802" checksum="42F4B490C2D53A56" modified="2010-04-20" version="1">MSNKIPAATDTSIKARIQRVGGHMAGMVMPNIGAFIAWGLITALFIPKGWIPNETMAALVDPMVKMLLPLLIAYTGGRMVHGHRGGVIGAVATVGIVVGADVPMFLGAMIMGPLAAYLMKLIDKPLESRIKPGFEMLVNNFSAGILGAGLAMLGLWGIGPVISKVTVFLGDQVKWLVEHNLLPLASLIVEPAKVLFLNNAINHGAFTPLGTVESKETGQSILFMIESNPGPGLGLLLAFLFFGPRKLRGSTPAAIAIQFLGGIHEIYFPYVLMKPRLILAVMAGGVTGVATFMITGVGLTSAPAPGSIFAFWLTSPPGNLVGMMTGVVLAAAASFAVAGLLLGFGRKADPADEAVAAVETAPTADTGAAVAIPAPATSPETDADRTEIAAELRVEDISKIVVACDAGMGSSVMLASQLRKQLKDHDVTVEHTPVDAIPADADVIICHEGLAERARSTAPGKPVIPIQVFLGDPAVTSLIATIKKGGVLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q237</accession>
    <name>D3Q237_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017475.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2213"/>
    <dbReference type="EnsemblBacteria" id="ADD41904">
        <property type="protein sequence ID" value="ADD41904"/>
        <property type="gene ID" value="Snas_2213"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2213"/>
    <dbReference type="eggNOG" id="COG1950">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120441_0_0_11"/>
    <dbReference type="OMA" id="TLGLFHI"/>
    <dbReference type="OrthoDB" id="1925503at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007165">
        <property type="entry name" value="Phage_holin_4_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37309">
        <property type="entry name" value="PTHR37309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04020">
        <property type="entry name" value="Phage_holin_4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="129" mass="14130" checksum="988A6E01553708BA" modified="2010-04-20" version="1">MQFLLRVLIYAVALWVTSLVVSGIHITAVTKLRDLGTLLLVALIFSLVNGFIKPIVQMLGCALYILTLGLFALVANALLFLLTEWFAELLHLPFRIDGFWAAFWGAIVMSIVSWVLSLVLPGGGKKSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2A3</accession>
    <name>D3Q2A3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, GntR family with aminotransferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019407.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4186"/>
    <dbReference type="EnsemblBacteria" id="ADD43836">
        <property type="protein sequence ID" value="ADD43836"/>
        <property type="gene ID" value="Snas_4186"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4186"/>
    <dbReference type="eggNOG" id="COG1167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_2_0_11"/>
    <dbReference type="OMA" id="VEDPGWA"/>
    <dbReference type="OrthoDB" id="1024978at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="436" mass="45880" checksum="5AA0464EE5D070FB" modified="2010-04-20" version="1">MVEQYQITGAGAAEIVASVETGVRTSRLAPGSALPPVRALAAELGLATATVAAAYRTLRQRGIVDTAGRHGTRVRQRPAIEHRGRTALPAGVLDLTTGEPDPALLPDLAVALRQVPTTPASYRDAGASPRLLAAARQRLAADGLSGTPTVTGGALDGIYRALSAHLRPGDRVAVEDPCWSNVRDLLASLGMHAVPVAVDDEGPTPEALEQALRSGASACVLTSRAHNPTGAVITAERARRLRAVLARHPGVLAIEDDHWAELSDDPLHPVADAAARWLFLRSVSKPYGPDLRLAIGCGDEATVARLHGQLRLSSGWVSTVLQHLVLGVWDDPLTTPALHRARDTYRDRRQALLTALAAHGVTARGHTGLNVWIPVPDETAAVTTLRDAGYAVAPGTPYRIASASGIRVSTSDLPLDHVEPLATVIAEAMHTPYPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2E9</accession>
    <name>D3Q2E9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019453.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4233"/>
    <dbReference type="EnsemblBacteria" id="ADD43882">
        <property type="protein sequence ID" value="ADD43882"/>
        <property type="gene ID" value="Snas_4233"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4233"/>
    <dbReference type="eggNOG" id="ENOG50348HA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1863939_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="137" mass="14671" checksum="9F78B28AE0D88CA8" modified="2010-04-20" version="1">MSDVDAVAAEATTDPNSPVLETDMHGRRWVFYRPDIRPAALRRYARLADKVTGGGEVADADAIELAAVAEDMLRSGLPDAETREAFDEAPFNGTDITALSEEYFEALGATVGESSASPAPSPTTVARSRPTSKRRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3F5</accession>
    <name>D3Q3F5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017567.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2307"/>
    <dbReference type="EnsemblBacteria" id="ADD41996">
        <property type="protein sequence ID" value="ADD41996"/>
        <property type="gene ID" value="Snas_2307"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2307"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027938_4_4_11"/>
    <dbReference type="OMA" id="QRAYPVR"/>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="37"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="246" mass="27086" checksum="0BFCFEEADB83515F" modified="2010-04-20" version="1">MELVYPPVILAAKAMFKTLGLRINVQGAEHIPDRGGAVIACTHHSYLDFIFCGFGAQPAKRLVRFMAKKQVFDHRVSGPLMRGMRHIPVDRSAGKAAYEEAVRQLRRGEVVGVFPEATISRSFTVKELKSGTVRMAAEAGVPILPMAVWGTHRLWTKGRPRNLTKRGIAISIRVGSPFAADEDASLDTSTKQLRGRMQQLLDGIQADYPSKPADGEDPWWVPGHLGGTAPTPEEAAELDNRHREDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3F8</accession>
    <name>D3Q3F8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ADD41999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ADD41999">
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        <property type="gene ID" value="Snas_2312"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2312"/>
    <dbReference type="eggNOG" id="COG1680">
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    </dbReference>
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    <dbReference type="OMA" id="HGYTNER"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
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        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048208" evidence="1">
        <location>
            <begin position="31"/>
            <end position="406"/>
        </location>
    </feature>
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        <location>
            <begin position="50"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
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    </evidence>
    <sequence length="406" mass="43163" checksum="1813EBC73BC413E5" modified="2010-04-20" version="1">MRMPRRRYQIGALLGITGLAVAIVTANAVADPTKTDGQAQADAIRDAAKSTGTVVVVDDGESVKHYGSGTTTFGKDDVPDADDQFRVASNTKMFVSTVLLQLAEEDKLDLDAPIGDYLPGLVKGEGIDETKITVRHLLQHTSGLADNLTADVIADPRLQWNPPTPEDMVKLGLRHGSKSEPGAKFSYSNTGYTILGILIEKLTGQRVGEAIDERIVKPLDLKETSYAYAGDKEMKGPHFRGYLGVPPALFEVSGHEPGIWAAAGALVSSGSDLTTFLDALLNGDLLTDPSLEQMKESFPDAHYGLGLQEAELPCGAAWGHTGHVIGYVSYSFTTGDGRSIFIGVNTSSTGLTNPAEEMSKALTSALCGEDTPPSDSVTKMISDDLDEAASQAEAVSDKKSKIYDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2332</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
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        <lineage>
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            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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    </organism>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
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                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ADD42019">
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        <property type="gene ID" value="Snas_2332"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="MetI-like"/>
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        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
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        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
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        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
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        <location>
            <begin position="74"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="276" mass="30727" checksum="481896ACBA6D77DA" modified="2010-04-20" version="1">MTTQTKPPGRLTVAWRPIRTLLWRLLLWFGLPVALLTIWWLASDGSRDFYWPSLRDILHTFTQLWTLDRWRADILPSLARLAAGYAAASALGIALGVLIGLNWRIRALCEPVLEFFRAVPPPVLVPVIMLFTGVGDTMKAVVIVSGCVWPILLNTVTGVRGIDPVQRDTCAVFALRPLTRLRRLVLPAAAPHIATGMRQALSIGIILMVVSEMFAAHSGLGFAIVQFQRGFQIPEMWSGIILLGLIGVTLSLLFTVVERRVLAWYHGMRRTEGTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Q4</accession>
    <name>D3Q3Q4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
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        <lineage>
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            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
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            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ADD43971">
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        <property type="gene ID" value="Snas_4324"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4324"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="OMA" id="VGMYANS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF103473"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="46"/>
        </location>
    </feature>
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        <location>
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            <end position="78"/>
        </location>
    </feature>
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        </location>
    </feature>
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    </feature>
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            <end position="171"/>
        </location>
    </feature>
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        <location>
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            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="24"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="516" mass="53578" checksum="8504D0C87A41D7DB" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4D2</accession>
    <name>D3Q4D2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015663.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0375"/>
    <dbReference type="EnsemblBacteria" id="ADD40092">
        <property type="protein sequence ID" value="ADD40092"/>
        <property type="gene ID" value="Snas_0375"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0375"/>
    <dbReference type="HOGENOM" id="CLU_2902061_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="62" mass="7170" checksum="6046449CE0E8CC95" modified="2010-04-20" version="1">MISENPKTWGTYGTFTLDGQSLTYHVAHGHYWRDDIDGGTRLFQDRLDGRDLLILIAEMRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Q5</accession>
    <name>D3Q4Q5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017656.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2402"/>
    <dbReference type="EnsemblBacteria" id="ADD42085">
        <property type="protein sequence ID" value="ADD42085"/>
        <property type="gene ID" value="Snas_2402"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2402"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_1_11"/>
    <dbReference type="OMA" id="PARYCGA"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="19"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="259" mass="27938" checksum="1932BA34E1961854" modified="2010-04-20" version="1">MSEQTVPTVAGGLSRADARRNRAKVLAAAQRAFAEEGFSVSLGEIANRAGVGAGTVYRHFPSKDDLLEAVLSQRIERLTRLADEYGDSADPGAGFFAFVDEVLSSTTGNKDMCDLFERQDGWPRALLLTSGRRFNDALERLLAAAQRHGAVRADIDSADIQELFTGLVAMRRYRDGAELPGRMTLILIDTLRATPASVMKSDTAAHNRDEINRDTEKHNATAPACPVCGGPVRASAAGRPARYCGAACRQKAYRQRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4S9</accession>
    <name>D3Q4S9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha/beta hydrolase fold-3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2426</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017680.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2426"/>
    <dbReference type="EnsemblBacteria" id="ADD42109">
        <property type="protein sequence ID" value="ADD42109"/>
        <property type="gene ID" value="Snas_2426"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2426"/>
    <dbReference type="eggNOG" id="COG0657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_13_1_11"/>
    <dbReference type="OMA" id="KAWIIAP"/>
    <dbReference type="OrthoDB" id="1587940at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002168">
        <property type="entry name" value="Lipase_GDXG_HIS_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01173">
        <property type="entry name" value="LIPASE_GDXG_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="4">
        <location>
            <begin position="69"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="308" mass="33549" checksum="BACE194CAFAD91D3" modified="2010-04-20" version="1">MPSQESETIKRHWQSVRKAWDEPRGPQPDNESWGNLTAEPREVDYLEIEAAGLPAMWAIPKNSAADRVLLCLHGGGFVGGSIYSHRKLFGHLAKAAGVRALLLGYHLAPKHVFPSQVDEAVAGYRWLLEQGFDAGHIAFTGDSAGGGLSITAQLRAREQGLPVPAATLPFSPWVDMEVGGKSYETNRPREPYFHKETVEMLAGVYLGPDGDLRDPHANPLHADLSGLGPMYIQAGGDEGLLDDARLLADHARRAGVDVRLDVFDDMLHTFQMGAGRVPEADDAIRRMADWVRSKLDLTDGRDQAGSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4V3</accession>
    <name>D3Q4V3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017704.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2450"/>
    <dbReference type="EnsemblBacteria" id="ADD42133">
        <property type="protein sequence ID" value="ADD42133"/>
        <property type="gene ID" value="Snas_2450"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2450"/>
    <dbReference type="HOGENOM" id="CLU_2829148_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="66" mass="7132" checksum="767477AF6D06ED5E" modified="2010-04-20" version="1">MPDDLTEPYVADDTTTYDGMDVDGSDSGGYEPLPDDTTTYDGMDVDGSDDSSELEGYEQPSDTTTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q504</accession>
    <name>D3Q504_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2502</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017755.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2502"/>
    <dbReference type="EnsemblBacteria" id="ADD42184">
        <property type="protein sequence ID" value="ADD42184"/>
        <property type="gene ID" value="Snas_2502"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2502"/>
    <dbReference type="eggNOG" id="ENOG5032UAS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109394_0_0_11"/>
    <dbReference type="OMA" id="TIHRYEM"/>
    <dbReference type="OrthoDB" id="1336167at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="182" mass="20110" checksum="316A6F8427AABE0F" modified="2010-04-20" version="1">MRPEPGQVLHFSEDPTITRFTPRPSPRLAAAYVWAVGSRRCPDYWFPRECPRAMAWIEPHTTDADRDRILGPGGGHRVHAVEFGWLEAMRTVELYGYRLPANAFRPLDESDSAANGSPALVAVEAVTPLGPPERVGDLFALHAEAGIQLRVLDNLRTFWDAVIDSSLGFSGIRLRNAKPAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q576</accession>
    <name>D3Q576_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4480</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019696.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4480"/>
    <dbReference type="EnsemblBacteria" id="ADD44125">
        <property type="protein sequence ID" value="ADD44125"/>
        <property type="gene ID" value="Snas_4480"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4480"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="PKYLFCD"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="256" mass="27910" checksum="C66F0C5ECA959277" modified="2010-04-20" version="1">MTTTTTAAARAHNVWKVYGTGEAQVIALHGVSAEFGAGQFTAIMGPSGSGKSTLMHCLAGLDHTNRGEVHIGDTKVTGLSDRGLTKLRRQKVGFIFQQFNLLPTLTAQENILLPLSIAKQKPDAAWFDRVIDTVGLRDRLSHRPSQLSGGQQQRVACARALVQRPEVIFADEPTGNLDSRSGTEVLKFLRDSVDQFGQTIVMVTHDPVAASYADRVLFLADGRVVDEMLEPTADRVLDELKRFEEIVDSVKAGEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q590</accession>
    <name>D3Q590_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4494</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019710.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4494"/>
    <dbReference type="EnsemblBacteria" id="ADD44139">
        <property type="protein sequence ID" value="ADD44139"/>
        <property type="gene ID" value="Snas_4494"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4494"/>
    <dbReference type="eggNOG" id="COG1764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106355_1_0_11"/>
    <dbReference type="OMA" id="ANCPVSQ"/>
    <dbReference type="OrthoDB" id="1655733at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019904">
        <property type="entry name" value="Peroxiredoxin_OsmC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03562">
        <property type="entry name" value="osmo_induc_OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="14470" checksum="65E4F9B664E757B1" modified="2010-04-20" version="1">MATVRTARTNWEGDLTGGAGVVHFESSGRPDAEVTWAARSQDANGKTSPEELIAAAHSSCFSMALSAGLAKAGTPPQSLDTSAEVTFDPAAGGITKIRLTVRGDVPGISAEEFNAAAADAKANCPVSKALGAVQDITVDAALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5C0</accession>
    <name>D3Q5C0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenosine deaminase</fullName>
            <ecNumber evidence="4">3.5.4.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4524</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.4" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4524"/>
    <dbReference type="EnsemblBacteria" id="ADD44169">
        <property type="protein sequence ID" value="ADD44169"/>
        <property type="gene ID" value="Snas_4524"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4524"/>
    <dbReference type="eggNOG" id="COG1816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_803888_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="PTHR11409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A_deaminase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="345" mass="37297" checksum="64545B644768D54E" modified="2010-04-20" version="1">MLLKADLHLHQEWSPRLDRVLARRHSRVPFDWKTWRETLTTQVPPGVARLQRLSRVFPAPAEADTDDAFVERVTDALEESAAAGSCYTELRFGHDTVMRPVFMPLFRQAEEKVAAKYPGFRAEAVASLLLWQEPERLDAAIAECRRAAAEGLAGVDLLNVPYSSEADWQTGRKVVDAATDAGLGVTVHAGEFSSANIAAVACMDGVTRIGHATHAPTDPWLLELLAARGITIEVCLTANLILGAVPTLADHPLRRFLDANIPVALGTDNPIQFGTTIDHEYTLASRLGLSESDLSRLTRNAIDAAFTTPDRKTALRADVDAAPASVLTPHVAATVESGDLCSPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5G6</accession>
    <name>D3Q5G6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6458 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021597.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6410"/>
    <dbReference type="EnsemblBacteria" id="ADD46026">
        <property type="protein sequence ID" value="ADD46026"/>
        <property type="gene ID" value="Snas_6410"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6410"/>
    <dbReference type="HOGENOM" id="CLU_173182_0_0_11"/>
    <dbReference type="OrthoDB" id="2031661at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045597">
        <property type="entry name" value="DUF6458"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20059">
        <property type="entry name" value="DUF6458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6458" evidence="3">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD46026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="97" mass="10926" checksum="7E9EAA5C49C91F1D" modified="2010-04-20" version="1">MGLGGSIFFLVLGAILTFAVRDSPEWIDLQTTGWIFMIAGVVGIVLTSWYAKHQKRVHKEVHDRYQANRIARRQAIKRNDARRAAESEQSNPGSSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5I3</accession>
    <name>D3Q5I3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021614.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6427"/>
    <dbReference type="EnsemblBacteria" id="ADD46043">
        <property type="protein sequence ID" value="ADD46043"/>
        <property type="gene ID" value="Snas_6427"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6427"/>
    <dbReference type="eggNOG" id="COG1167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_6_11"/>
    <dbReference type="OMA" id="MRLNFTY"/>
    <dbReference type="OrthoDB" id="1024978at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="61"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD46043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="414" mass="44621" checksum="A7846AD5EAAAA95F" modified="2010-04-20" version="1">MSTKTTQDDYSDRYAARVHGMAQSEIRALFSVASRPEVVSLAGGNPFTAALDMDELGEMFARLLAEDGAKSLLYCPGQGDVALREQICEVMALTGIDVTAGASPDDVVVTVGAQQGLDLLCRVFLDPGDVVLAEGPTYVGALGVFQAAQARVRHVAMDDEGLIPAALETAIAEAPTRPKFLYTVPTYQNPTGVTLSESRRQEVLEICDRHGLLIVEDDPYGMLSFDGNTATPLRARRSENVFYVGTFSKIFAAGLRVGWVLAPPAVRDKLVMASEAAVLCPSTFTQAAATRYLTTMPWQQQVKTFSTLYCERRDTMLAAMSDHFPAAMTWTHPGGGLFVWANLPEGLDSKAMLPQALAARVAYVPGTGFYADGSGAGQMRLNFSFPPGDEIREGIRRLSGVINSAARLRDTFTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5X3</accession>
    <name>D3Q5X3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0558</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015843.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0558"/>
    <dbReference type="ESTHER" id="stanl-d3q5x3">
        <property type="family name" value="Duf_1023"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40272">
        <property type="protein sequence ID" value="ADD40272"/>
        <property type="gene ID" value="Snas_0558"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0558"/>
    <dbReference type="eggNOG" id="COG4099">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025057_0_0_11"/>
    <dbReference type="OMA" id="VIAWADY"/>
    <dbReference type="OrthoDB" id="2018813at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010427">
        <property type="entry name" value="DUF1023"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06259">
        <property type="entry name" value="Abhydrolase_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="368" mass="39397" checksum="A0A7E373FE446FF0" modified="2010-04-20" version="1">MAAISVPPLGEKPLLVKSWWEALGNGERLGLLADRPERIGGMDGIPVEVRDRANRADLTAILEAIEVWGKKAEQLPFGQLASEVGERMARILQKRASRQSLRILSDWIERPSPVDGLAYFLIDFDVSGDGKAVVALGNPDISDNVAVFVPGAFAAVDEALDDYARMDAMAGDAASRDGGKKTAVVRWLGYDAPDSIVPDAASPRFAENAAVSLDRFIAGLRVTRDGPRTRITMVGHSYGSTVIGIADRERRLSVDGMVFVGAPGVGVVQADKLSVGAEKVWATVAPGDLIIKTPPGLLGIPPCKPGFGAKIFTCADTGRQPWFLSMFGIPRDAIKAHNGYWNPGNVARDNIAAIVLGHRDKVKLKKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q684</accession>
    <name>D3Q684_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2579</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017830.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2579"/>
    <dbReference type="EnsemblBacteria" id="ADD42259">
        <property type="protein sequence ID" value="ADD42259"/>
        <property type="gene ID" value="Snas_2579"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2579"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="GTQPDFE"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="142"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="213" mass="22279" checksum="C84A6C2812A7D985" modified="2010-04-20" version="1">MTIALLIVDDHPVVRDGLRGMLSTQSDFTVVGEAAGGEEALAMLSDHDVDVMLTDLRMPAPSGAALIRLIAKRHPRVRVLVLTTYDTDADVLPAMEAGAVGYLLKDTPRQDLYRAVRSAADGETALSPSVAARLVDRLRSPGPARSSALSAREIEVLSLVAAGNSNKAIAAALFISEATVKTHLLHIYGKLGVNDRAAAVAAGYDSGLLGPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6M3</accession>
    <name>D3Q6M3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GTPase Era</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">era</name>
        <name evidence="12" type="ordered locus">Snas_4623</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019837.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4623"/>
    <dbReference type="EnsemblBacteria" id="ADD44266">
        <property type="protein sequence ID" value="ADD44266"/>
        <property type="gene ID" value="Snas_4623"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4623"/>
    <dbReference type="eggNOG" id="COG1159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038009_0_2_11"/>
    <dbReference type="OMA" id="WAEVDVI"/>
    <dbReference type="OrthoDB" id="984717at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04163">
        <property type="entry name" value="Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00367">
        <property type="entry name" value="GTPase_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030388">
        <property type="entry name" value="G_ERA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTP-bd_Era"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="PTHR42698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00436">
        <property type="entry name" value="era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51713">
        <property type="entry name" value="G_ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Era-type G" evidence="11">
        <location>
            <begin position="6"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="KH type-2" evidence="10">
        <location>
            <begin position="204"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="G1" evidence="8">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="G2" evidence="8">
        <location>
            <begin position="40"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="G3" evidence="8">
        <location>
            <begin position="61"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="G4" evidence="8">
        <location>
            <begin position="123"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="G5" evidence="8">
        <location>
            <begin position="152"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="61"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="123"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD44266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="33135" checksum="F6BBC18ECD532D46" modified="2010-04-20" version="1">MTDDYRAGFACFVGRPNAGKSTLTNAIIGSKIAITSNRPQTTRHVVRGILHRPDSQLILVDTPGYHKPKNVLGKRLNEEVRETWSEVDVIGLCIPANEKIGPGDRYITREITAQKAKVVAVVTKIDLVSKTDVAKQLMAVNDMADFADIVPCSAVSGEQVDVLVDVLSKYLPTSPQLYPDDMITDEPERVMIAELVREAALEGVRDELPHSIAVVIEDVEIEDLEDGPRTKIYAEIYVERSSQKAIVIGKAGSRLRTVGTHARKEIAKLLNQRVYLDLHVRVAKDWQTNPKYLQRLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Q2</accession>
    <name>D3Q6Q2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase domain protein TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4652</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019866.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4652"/>
    <dbReference type="EnsemblBacteria" id="ADD44295">
        <property type="protein sequence ID" value="ADD44295"/>
        <property type="gene ID" value="Snas_4652"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4652"/>
    <dbReference type="eggNOG" id="COG1082">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050006_8_2_11"/>
    <dbReference type="OMA" id="GLAMESF"/>
    <dbReference type="OrthoDB" id="1007505at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="28"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="290" mass="31231" checksum="1B08ACB7F2A85B11" modified="2010-04-20" version="1">MNHPVGVNTWVWTSPLTDAALAELAPRIRDWGFDAVELPVENPGDFDPGRAAELLSELDLKPSVVLVMGPGRELVAAPDPVIESTQAYLRHVADVAARVGSPVIAGPAYTSVGRTWRLSDAERRDCYALLRDNLRPVLDHAARRGVRLAVEPLNRYETSLLNTVEQTLDALAGLPEDQCGIALDVYHQNIEERDIPAAIRAASGRIAHVQVCGNDRGAPGADHLDWPGILAALADSGYTGPLIIESFTADNATIATAASIWRPLATTQDDLAREGLAFLRAAQTEQKDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6R6</accession>
    <name>D3Q6R6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015886.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0601"/>
    <dbReference type="EnsemblBacteria" id="ADD40315">
        <property type="protein sequence ID" value="ADD40315"/>
        <property type="gene ID" value="Snas_0601"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0601"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="DLLACCH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTAD" evidence="1">
        <location>
            <begin position="99"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="928" mass="100176" checksum="C8920907FE8C8BD4" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q786</accession>
    <name>D3Q786_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2680"/>
    <dbReference type="EnsemblBacteria" id="ADD42357">
        <property type="protein sequence ID" value="ADD42357"/>
        <property type="gene ID" value="Snas_2680"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2680"/>
    <dbReference type="HOGENOM" id="CLU_1894911_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="149" mass="15960" checksum="B51E13ACE8ED2584" modified="2010-04-20" version="1">MNDRPTASSGDSGSDRPDIPADAVSLDRKDMFGLAEALRSDSEQFLERAREIAAVIGSGNTGHREDRPWGADPRNLPAQPIVEFHNELADRAQRLLDSVGTGMSNLSGITDAIVARFSDQDALNSATVPQISSVTRLDVPSQESSPSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q787</accession>
    <name>D3Q787_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017929.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2681"/>
    <dbReference type="EnsemblBacteria" id="ADD42358">
        <property type="protein sequence ID" value="ADD42358"/>
        <property type="gene ID" value="Snas_2681"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2681"/>
    <dbReference type="HOGENOM" id="CLU_711537_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038332">
        <property type="entry name" value="PPE_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="383" mass="42228" checksum="51D6D0152E29631F" modified="2010-04-20" version="1">MATFNSYTVDEIREIVDPDHPETLLEQAKGWAEMADLLSEYGVLLEQRLELVEDSWTGDAARLYFDEVKRMQEYIEESAERATTNAGLWFLIGTLAGIAKHDVSYIHKLWKDLDNVTDAVGLGFILEAIGVDKAVEDFKRMPYDVASRQIMEATATAAEESYSQMRDFEEFKPPPDVDGSGPTLQSVSAVAPPGGAVSLPSTTIVSNAAMPPLGPVAMRPVVPGVIGSRPGMTSMPRPMMGPGHTVRPVIGQRTGESQQTKTPGRLIGRYGVVSATPDVDMRDPKASRIHYGGDDVNRGVIKNNDPQRAAEEARFKLEEEVLRLRERAFAHRADDLTPAHTQHVLPGIVGDDSGWDRKTHDPGPVAFEMRRRPDRDDDAWTVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7C9</accession>
    <name>D3Q7C9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Molybdopterin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2724</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2724"/>
    <dbReference type="EnsemblBacteria" id="ADD42400">
        <property type="protein sequence ID" value="ADD42400"/>
        <property type="gene ID" value="Snas_2724"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2724"/>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_13_4_11"/>
    <dbReference type="OMA" id="DGPPCCY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="5">
        <location>
            <begin position="31"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="542"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="741" mass="78818" checksum="8124922199C2A422" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7E6</accession>
    <name>D3Q7E6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2741</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017988.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2741"/>
    <dbReference type="EnsemblBacteria" id="ADD42417">
        <property type="protein sequence ID" value="ADD42417"/>
        <property type="gene ID" value="Snas_2741"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2741"/>
    <dbReference type="eggNOG" id="COG1510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078983_0_0_11"/>
    <dbReference type="OMA" id="HGYVRRE"/>
    <dbReference type="OrthoDB" id="1265289at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_38" evidence="3">
        <location>
            <begin position="5"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="102"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="232" mass="26174" checksum="8FFF00FD2E4E3B6B" modified="2010-04-20" version="1">MASGHLTHEERRRIAHGLAEGLGYAEIARHLDRPTSTVSREVARNGGARDYRPNRAHQAARQRARRRGPRPAPTAPADAAGRDSRAVLDFEERFAEMMIHTGLQPMPSRVLARLFTSDTGSLTAAELVTRLRVSPASVSKAVGYLEQLHMITRERDNRRERYLINDDVWYESWKSSMRSIGIWADTARQGAEILGATTPAGARLTLASQFYDFLRHDMEEAAELWRRITTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7H7</accession>
    <name>D3Q7H7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Radical SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_4676</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the radical SAM superfamily. NifB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44319">
        <property type="protein sequence ID" value="ADD44319"/>
        <property type="gene ID" value="Snas_4676"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4676"/>
    <dbReference type="eggNOG" id="COG0641">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009273_3_1_11"/>
    <dbReference type="OMA" id="PYKGTMK"/>
    <dbReference type="OrthoDB" id="1172757at2"/>
    <dbReference type="UniPathway" id="UPA00782"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023885">
        <property type="entry name" value="4Fe4S-binding_SPASM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005980">
        <property type="entry name" value="Nase_CF_NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43787:SF3">
        <property type="entry name" value="PTHR43787:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04085">
        <property type="entry name" value="rSAM_more_4Fe4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="9">
        <location>
            <begin position="67"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD44319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="434" mass="48676" checksum="348D1D6FEE1E8446" modified="2010-04-20" version="1">MTLHSARTGAIGVVPPDDVDAARTALKPRTETPGPLKGIHADLLKGGFLVPKGTNEAYLVNDSYQTRYLERGLHLIVMPTEQCNFRCVYCYESFKRGEMSPEVEASVRKLVDGQPDLDHLTLSWFGGEPLMAREVVFRLTDYLRASCARRGATFLCHATTNGYYLDPDYVDRVVPAGLQHFQITLDGVQEEHDKRRISADGEPTFDKIWGNLRYLRKSDHEFTASIRHNYDPDNFARFDEFIEMLRAEFAGDSRFAVELSPIGKWGGANDDNLNVCEGRDLVTSLFEAKRKLSAMGFRDSLAMSMMEPNGSTCYAANPRSFVIGPTAELYKCTVELDYHDRNVVGRLLPDGTLDLDWKKMALWTETDGMDEGKKCTTCYFRPSCHGAVCPKEWMDEPECGCPPVKLGIGQQLNLIRTESLFQKPVNAGPTCPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7I9</accession>
    <name>D3Q7I9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019902.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4688"/>
    <dbReference type="EnsemblBacteria" id="ADD44331">
        <property type="protein sequence ID" value="ADD44331"/>
        <property type="gene ID" value="Snas_4688"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4688"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_13_0_11"/>
    <dbReference type="OMA" id="IPDPYMF"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="462" mass="50549" checksum="84D9771D4D51FCE1" modified="2010-04-20" version="1">MTQGIDVARLRSTMAALLAEYQIPSAALGVVADGEVTTVAVGDARLSPPRPATTETVYQCGSLTKTFTALAFMRLVDEGKVDLDRPVRTYLPDFAVADADTTARLTPRQLLNHTNGIEEAFGDPGEDTDVYRRMVDNIADAPQVQPLGHTHGYSAALGYAILARVMEVVEDKPWDAIMAERLFAPMGLTSTNTWREQVDPERAATGYILRSIEEGPIETPIDHLPRSYGPGGNITSTIGEVLTLARVILDGGTAPNGNRIVSATAVKEMMESRVPIPDPYMFGPYWGLGLITCDWDGHTVYAHDGSTIGQNARLRILPEQRLAIALLTNGGPRESFYKRLFNEILPEFGAPTVPELPQPDPDLVLDPSRYEGVYERPGARFEVRARDGGLGLTVFVDPEQAAFLGQPERITYPLLPVSPTHFLMPSDNPLEDTQTVAIHDFADGRARYLHTNCRLTPRTGDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7P1</accession>
    <name>D3Q7P1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF418 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4741</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019954.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4741"/>
    <dbReference type="EnsemblBacteria" id="ADD44383">
        <property type="protein sequence ID" value="ADD44383"/>
        <property type="gene ID" value="Snas_4741"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4741"/>
    <dbReference type="eggNOG" id="COG2311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039610_1_0_11"/>
    <dbReference type="OMA" id="RTELYIW"/>
    <dbReference type="OrthoDB" id="1742337at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04235">
        <property type="entry name" value="DUF418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="DUF418" evidence="2">
        <location>
            <begin position="217"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="392" mass="42203" checksum="742D2EA348638E17" modified="2010-04-20" version="1">MSETSPTPVPAAVPVARRSLAPDLARGVMLLVIAAAHGRIMAEMFGGGHATSTLDAVTELLLPMLVDARGYPMFAALFGYGLCQIYLRRQAQSWPWPPIRSLVRRRGRWLLLFGLAHVVLLFFGDILSVYGLVALAFAGVLRFSDAKLLRHAAVWLIVGSGLYAVLLTLGSGDTTEGATVMGADPITDLIGRLTMWPVFTPFMFVTTVFPFLIGVWAARRRILEEPTRHLALLRRVAFVGIPMGIVGGLPLGLHNMGAWHGGTAAIYGVEWLTTVAGYMGGLGYAALIGLIAARIGDRPGRIATALAATGQRSMTSYLLQSVAWMILFPPYLVGWGPQLSAASAVAVGAGVWLATVLIAELMRRKGWRGPAERALRNRTYRVRAPKPLAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Y4</accession>
    <name>D3Q7Y4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminopeptidase N</fullName>
            <ecNumber evidence="4">3.4.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Snas_0777</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016060.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0777"/>
    <dbReference type="MEROPS" id="M01.032"/>
    <dbReference type="EnsemblBacteria" id="ADD40489">
        <property type="protein sequence ID" value="ADD40489"/>
        <property type="gene ID" value="Snas_0777"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0777"/>
    <dbReference type="eggNOG" id="COG0308">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014298_2_0_11"/>
    <dbReference type="OMA" id="VSHYDLR"/>
    <dbReference type="OrthoDB" id="771837at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048301" description="Aminopeptidase N" evidence="11">
        <location>
            <begin position="30"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1_N" evidence="13">
        <location>
            <begin position="55"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="12">
        <location>
            <begin position="322"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD40489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="503" mass="55037" checksum="5629F42B1F9F6BA1" modified="2010-04-20" version="1">MTMWTKARVGFGALAAGLATVMLATTAAAAPTPGAPGVGDPYYPGAGNGGYNVGHYDIRLTYQPKTDELSGQTTIKATATQDLSRFNLDFGLTVSAITVNDAAAEFATDPADPSELIVTPSSPVAKGQSLRVLVKYSGIPSTVVIEGRYTAWTRTATGGFAVSQPRVAEWWFPSSDHPSDKATFAVSAEVPDGTSALSNGVLAGKDDERPGWTRWNWKSKYPMATYLAFIALGEYEVHQSTWRGKPYITAYDESLKPEWLATAKEQIGTTPEVTDFLSDKFGPYPFEAIGGVAVNGIGYAIENQTRPAYGTSFWDLPEPGWVIAHEQAHQWFGDSVSVADWSHMWLNEGFATYAEWLWSEERGLGTADQLAQAFYEKYPADDPFWQVVVADPKKIFESAVYERGAMALHALRGEVGDRKFFEILRSWHKLKKGGNATTAEFIARAERVAGEQLDELFETWIYAKGKPATSPNGADVQVKGEPKSFDGMVKLHKHFVEHGHGQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q820</accession>
    <name>D3Q820_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0813</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0813"/>
    <dbReference type="EnsemblBacteria" id="ADD40525">
        <property type="protein sequence ID" value="ADD40525"/>
        <property type="gene ID" value="Snas_0813"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0813"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_135_4_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="34"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="523"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="244"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="669" mass="68478" checksum="958D8011FBDA0178" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q842</accession>
    <name>D3Q842_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsH</name>
        <name evidence="9" type="ordered locus">Snas_0835</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the central section; belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016118.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0835"/>
    <dbReference type="MEROPS" id="M41.015"/>
    <dbReference type="EnsemblBacteria" id="ADD40547">
        <property type="protein sequence ID" value="ADD40547"/>
        <property type="gene ID" value="Snas_0835"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0835"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_16_1_11"/>
    <dbReference type="OMA" id="QYGMTER"/>
    <dbReference type="OrthoDB" id="190468at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="8">
        <location>
            <begin position="212"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="626"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="220"/>
            <end position="227"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="518"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="671" mass="72665" checksum="A8549F27F4FDE19F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8L7</accession>
    <name>D3Q8L7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4818"/>
    <dbReference type="EnsemblBacteria" id="ADD44459">
        <property type="protein sequence ID" value="ADD44459"/>
        <property type="gene ID" value="Snas_4818"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4818"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_236932_0_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="746"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="804"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="756"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1849" mass="201627" checksum="977F6E0B9DF26FFA" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9N1</accession>
    <name>D3Q9N1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020148.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4936"/>
    <dbReference type="EnsemblBacteria" id="ADD44577">
        <property type="protein sequence ID" value="ADD44577"/>
        <property type="gene ID" value="Snas_4936"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4936"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027938_4_0_11"/>
    <dbReference type="OMA" id="PFKWVSK"/>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="35"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="245" mass="26848" checksum="46390B39E666BFB8" modified="2010-04-20" version="1">MLYSVLKWVVVGPWLWLIYRPKVEGGANIPKEGAAIIASNHVSFSDSIFLPLVVRRKIIFVAKSDYFTGKGFKGWFSRFFFSGVGCIPLDRTGGSAAQAALDTGLRVLREGELFGIYPEGTRSPDGKLYKGKTGVGRMVMQSGAPVIPVAMINTGELQPIGKRLPKIGRVRIKIGEPIDFSRYAGLAGERAVERAITDEIMYALMELSGQDYVDEYATKVKALKDKADASAAEAEAVRIERQRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9P2</accession>
    <name>D3Q9P2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4947"/>
    <dbReference type="EnsemblBacteria" id="ADD44588">
        <property type="protein sequence ID" value="ADD44588"/>
        <property type="gene ID" value="Snas_4947"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4947"/>
    <dbReference type="eggNOG" id="COG3462">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159099_1_3_11"/>
    <dbReference type="OMA" id="PGPWILF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="93" mass="10734" checksum="953B31C9AF5D385F" modified="2010-04-20" version="1">MNTYHEAVMTVASQDGPWNHDGPWHHGGGGPWFLLVPLFWIAVVVAIVAIVRRRNGHWTRNHGAEGVLRERFARGEIPEEEYRQRLEVLRAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9V8</accession>
    <name>D3Q9V8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycoside hydrolase family 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5017</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020225.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5017"/>
    <dbReference type="CAZy" id="GH30">
        <property type="family name" value="Glycoside Hydrolase Family 30"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44654">
        <property type="protein sequence ID" value="ADD44654"/>
        <property type="gene ID" value="Snas_5017"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5017"/>
    <dbReference type="eggNOG" id="COG5520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014379_3_1_11"/>
    <dbReference type="OMA" id="FGGIAWH"/>
    <dbReference type="OrthoDB" id="447059at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004348">
        <property type="term" value="F:glucosylceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033452">
        <property type="entry name" value="GH30_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001139">
        <property type="entry name" value="Glyco_hydro_30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033453">
        <property type="entry name" value="Glyco_hydro_30_TIM-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069">
        <property type="entry name" value="PTHR11069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02055">
        <property type="entry name" value="Glyco_hydro_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17189">
        <property type="entry name" value="Glyco_hydro_30C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00843">
        <property type="entry name" value="GLHYDRLASE30"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048983" evidence="5">
        <location>
            <begin position="30"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_30" evidence="6">
        <location>
            <begin position="87"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_30C" evidence="7">
        <location>
            <begin position="422"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="484" mass="53579" checksum="19747FB86DB7AA07" modified="2010-04-20" version="1">MPRFELRRAQVLTAVSVLGLVMLVVPGSAPVSGPRVDVWLTTTSDADGRVVDKGLEPQPSTRFGESDPAAGQLIEVDQGTTYQEFEGGGASFTDTAAWLMRGSGALDEADRDKVMEKLFDRREGIGLGFLRNPMGASDLARYAYSYDRTCCDLSDFSMDKDADVMALTKQAASINPGITVKAVPWSSPAWMKDNNDIEHRGWLRHEYYDEYAQYFVKYIQAYAKAGVDIDYVSPQNEPGCCYGTDYPSMNWNADALRAFTKDHLWPAFRKAGIDTKTLVFDWNWKNFPEMGAEQLADAELVDDPLFGGIAWHGYAGDPSTQSEVHKQYPGVKSFNTENSGGGWVDDQQREDMLNLIDYTRNWGRSWVKWSLAMDQNNGPTSGGCGTCTGLITVHNGGKRHGQVDYTVEYYTMGHLTKFVEPGAVRVASTDGAVRNVAWRNPDGSTALIAYNDTDKPRTIRIKADGHYASYRLPARASATFTWGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9W3</accession>
    <name>D3Q9W3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020230.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5022"/>
    <dbReference type="EnsemblBacteria" id="ADD44659">
        <property type="protein sequence ID" value="ADD44659"/>
        <property type="gene ID" value="Snas_5022"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5022"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="HEHTLAK"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="299" mass="33214" checksum="517D4DB6AE159BC5" modified="2010-04-20" version="1">MDVDIRLLRYFVAVAEEGNLTYAARRLFVSQPALTKQIKQLEHLLGVALFTRSKSGMTLTEAGRAFAERVPGVLADWDRTVRQTKNTGSREQRVLRVGYLASAANEATQRIIADFAEVRPDWRADMRQSTWSDPSAGLASGEVDVALVRLPFPGQEALRLEVLSIEDRMAVLPATHPLAERERLAFRELWDEPFVAAPAETGAWRDYWLGADERDDRPVRIGAVVDQPDDWLSAIANGYGIALAPESAARFYARPGIVYRPVSGVAPSRIAVAWAPEDDGNPVVRDFVRCCVANRPESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Y0</accession>
    <name>D3Q9Y0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016263.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0982"/>
    <dbReference type="EnsemblBacteria" id="ADD40692">
        <property type="protein sequence ID" value="ADD40692"/>
        <property type="gene ID" value="Snas_0982"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0982"/>
    <dbReference type="HOGENOM" id="CLU_2048302_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="120" mass="13162" checksum="0A37D2483A07A6DF" modified="2010-04-20" version="1">MVTYLVIFGIGVAILWGVGWSWLGRTERSRWWVDTLSGRQVVLGIAPGLGGLVTSGGILAIVKTAAAPLFDMTALLLALPMLASILVELAGIVGFLPKWWGPKWYREKIKTERKPPRYGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Z3</accession>
    <name>D3Q9Z3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Snas_0995</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016276.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0995"/>
    <dbReference type="EnsemblBacteria" id="ADD40705">
        <property type="protein sequence ID" value="ADD40705"/>
        <property type="gene ID" value="Snas_0995"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0995"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_13_3_11"/>
    <dbReference type="OMA" id="KFRRAHR"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023834">
        <property type="entry name" value="T7SS_pept_S8A_mycosin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03921">
        <property type="entry name" value="T7SS_mycosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049821" evidence="12">
        <location>
            <begin position="28"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="13">
        <location>
            <begin position="60"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD40705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="398" mass="41015" checksum="6F1988DCB0D7D31F" modified="2010-04-20" version="1">MPRLSTLLVAALLGGGIVVAQPTAAVAADCNPVSQEGNLDHTPWGQARMNAERVWPLTRGKGVKVAVIDSGVSDAHPVLDGKVDFGTDYVEPEEGQSKVGADCDLVGHGTSIAGIIAGREDKKSPFAGMAPDAELMSIRILPDLQGGGRELPGNLADAIREAADAGADVINLSVQVVHASVLEKAVKYAAKKGAVLVAAAGNMGGKDGTNEPQYPAAYDVDAVLAVSSMGPEGIKTDSSNTGKYVDLAAPGEEIIGPGPEGKGFTGGESATGTSFAAAFVSGTAALVKARHPDLSPKEIAGRMRATAQSPPHIRDEQVGFGTVDPYRAVTTNMDKTKPSKDMAGPGVDLKADTQIRPRTAAAIILGIAVALGIAFGCARFVMPIAWRKRKRRKALKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAA0</accession>
    <name>D3QAA0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="4">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Snas_1102</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1102"/>
    <dbReference type="EnsemblBacteria" id="ADD40812">
        <property type="protein sequence ID" value="ADD40812"/>
        <property type="gene ID" value="Snas_1102"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1102"/>
    <dbReference type="eggNOG" id="COG1194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012862_2_0_11"/>
    <dbReference type="OMA" id="WNNAIME"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004035">
        <property type="entry name" value="Endouclease-III_FeS-bd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="PTHR42944"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10576">
        <property type="entry name" value="EndIII_4Fe-2S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00525">
        <property type="entry name" value="FES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00764">
        <property type="entry name" value="ENDONUCLEASE_III_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="14">
        <location>
            <begin position="48"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD40812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="300" mass="32570" checksum="A7FF64D1CAA3B99B" modified="2010-04-20" version="1">MSDGALKVSGMNAVLASVMGHWFAENGRELPWRTPETTAWGVLVSEVMSQQTPVARVAPIWTEWMGRWPTPADFADAPAADVLRAWGRLGYPRRALRLHECAKAVVERHGGVIPDDVDALLALPGIGTYTARAVAVFAYRQRHPVVDTNVRRVVARWAHAKPDAGHATTTADLRDAEALLPSEPEEAARLSVALMELGALVCTARSPRCGDCPIARDCGFLASGESLPEGPSRKPQRYHGTTRYVRGQIMALLREAEHPVARVAIDGVWHETARREEALSGLISDGLVDALPGDRFALPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAG4</accession>
    <name>D3QAG4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018318.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3076"/>
    <dbReference type="EnsemblBacteria" id="ADD42747">
        <property type="protein sequence ID" value="ADD42747"/>
        <property type="gene ID" value="Snas_3076"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3076"/>
    <dbReference type="eggNOG" id="COG1570">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_737520_0_0_11"/>
    <dbReference type="OrthoDB" id="1647498at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="375" mass="41194" checksum="C08BBAB89B155D25" modified="2010-04-20" version="1">MDFKQLRDADVASLEKLVEPWSKATGKLETGSDTATNHVGNRIRSGAWTGQAAQTATTRVGFLEAQTEAGQTEGEAIHGILKQAVTAFNGSKKRLNDIIADVKDYDKLNLDDSGHVSVDKPDWKDMLGGGGLFGTHYIQLRVIASRFNDDIKDTLADARQLDGLVATALRAAANLDEPKNLDFNPNAKTDGTITLPDNGKVDWPDTFLSGAGDWYLKLGSIMSAEPFIDGTPAEQSAAIGDFVKTEVERAGGECKIVNGMMACVGAPDYMYERGGTTFGDTFVSRHKTWSDLENDPNQNLNDLMNHEKHHRDEQWRKHGVSFGRKYIEEEFHAWRLDYTNRYEADAEQHGGHTGYPVKPPPTPNPRPGPAPTPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAL2</accession>
    <name>D3QAL2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3124</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018366.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3124"/>
    <dbReference type="EnsemblBacteria" id="ADD42795">
        <property type="protein sequence ID" value="ADD42795"/>
        <property type="gene ID" value="Snas_3124"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3124"/>
    <dbReference type="eggNOG" id="COG4733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039495_0_0_11"/>
    <dbReference type="OMA" id="NGWWGEG"/>
    <dbReference type="OrthoDB" id="687243at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021345">
        <property type="entry name" value="DUF2961"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11175">
        <property type="entry name" value="DUF2961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="361" mass="40988" checksum="CFF922DD710E0426" modified="2010-04-20" version="1">MRESAYGQFGSSLRDLPRLRNSRRGRASSWDTTGGNDDRVTVEPGETVTLADLRGPGAITHIWCTTMLETPDGPWAVETDFLRRLVLKITWDDADHPSVLVPLGDFFGVGHGRTANFSSAPLQMSPQDGKGFNSWFAMPYAQGAKVELISELEQQKVFFYYYVDYESYARAEDDLGYFHAQWHRENPTDGQPRGESTVPQHLFEGPNLTGEGNYVILDATGRGHYVGCVFNVHNLSDSTDWDWYGEGDDMIFIDGEPWPPRLHGTGTEDYFNTSWCPTQTYHAPYHGITLPGRDNWKGQISMYRFHIEDPVLFNESIKVTIEHGHANKRCDDISSVAYWYQTLPHRPFDLAPVAQRLPRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAZ1</accession>
    <name>D3QAZ1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5152</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020358.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5152"/>
    <dbReference type="EnsemblBacteria" id="ADD44787">
        <property type="protein sequence ID" value="ADD44787"/>
        <property type="gene ID" value="Snas_5152"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5152"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="CGDRHHG"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="10"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="98"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="19476" checksum="4846AD240A0B0BA3" modified="2010-04-20" version="1">MENFDDYVRARGDALMRFAYLLCGDRHRAEDFVQEALIRCHRRWRAIERDGDPEPYVRKAVLRQFLSWRRRKVASEHVADEMAKTASGTDTAQAIAERDAMWRVLATLPRRQRAVLVLRYYEDLPDAQVAELLGCSAATVRVHVSRALAKLREHPGLPNFTIKTEERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB82</accession>
    <name>D3QB82_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsS</name>
        <name evidence="7" type="ordered locus">Snas_1189</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016470.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1189"/>
    <dbReference type="EnsemblBacteria" id="ADD40899">
        <property type="protein sequence ID" value="ADD40899"/>
        <property type="gene ID" value="Snas_1189"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1189"/>
    <dbReference type="eggNOG" id="COG0185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144911_0_1_11"/>
    <dbReference type="OMA" id="FPEMVGH"/>
    <dbReference type="OrthoDB" id="1893906at2"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="UniProt"/>
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        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="93" mass="10793" checksum="8930910F82B9A203" modified="2010-04-20" version="1">MPRSLKKGPFVDDHLLKKVEKAVESKSRNVIKTWSRRSTITPEMIGLTIAVHDGRKHVPVFISENMVGHKLGEFALTRTFRSHDKDDRKSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBB9</accession>
    <name>D3QBB9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1226</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016507.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1226"/>
    <dbReference type="EnsemblBacteria" id="ADD40936">
        <property type="protein sequence ID" value="ADD40936"/>
        <property type="gene ID" value="Snas_1226"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1226"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_15_2_11"/>
    <dbReference type="OMA" id="AINVFEV"/>
    <dbReference type="OrthoDB" id="1733296at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="423" mass="43222" checksum="A72BB8A94DE7D5BC" modified="2010-04-20" version="1">MALLADPPQTVATSRWRDVYLDAGARLLAQTGMFGAVTALLLLMQSSGAGGLAVSALTIATMLPMVVLAPVTGRLADRVDSRLLLIAAGLIRAVASLALAFTADTVTIIGLVVVLSIGTALLQPTLGALIPAMVTRDDLPKASAISQTAGTIGIMAGPALAGLLVGGFGTDAAMFLNAGCALATVAAAFAIKTRRGGVHTVPSPDSTTPGTRRVWRMADDGVVRMLILGIALVIGLVSAVNVVEVFFVRESFGATETQFGIISGAWALGMAGGAWLIAGPLRRNNNDGVVLIWMFASLALTCVVIGGMSGIYGSAWWLVPAFIVGGSLNGAENTINGVLMGRRVPAETRGQAQATFQGWVQGLALVGYVAGGVGVEFLSPRLMVLLCGAAGLVVVLALLPQVLRVARGVTTARTTRTPATEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBC5</accession>
    <name>D3QBC5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, Crp/Fnr family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1232</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016513.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1232"/>
    <dbReference type="EnsemblBacteria" id="ADD40942">
        <property type="protein sequence ID" value="ADD40942"/>
        <property type="gene ID" value="Snas_1232"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1232"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075053_3_0_11"/>
    <dbReference type="OMA" id="AEPTVHK"/>
    <dbReference type="OrthoDB" id="1596937at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="16"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="150"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="235" mass="25808" checksum="BC3DB72757550DD3" modified="2010-04-20" version="1">MRDSRLDGTIWPHGTLLRRLSSDDREDLLDLGTRRRVDAGTVLLRVGERGHNAILILRSFIKIAVPTVSGRETLLSIRLPGDMIGEASVLNDRPRTATATACGPGLVSVIGRSTLRDFLSTRPAVTMQLAGIVADRLRWANDRRVDAATYPVASRLARILSEMAMAYGVRSREGIEIGVELTQTEMSTLIGVSDVTLQRALRRLRDAGLVSTGYRRTIVTDAEGLRTFGERLDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBE6</accession>
    <name>D3QBE6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Guanylate kinase</fullName>
            <ecNumber evidence="2 9">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gmk</name>
        <name evidence="11" type="ordered locus">Snas_3157</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential for recycling GMP and indirectly, cGMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + GMP = ADP + GDP</text>
            <dbReference type="Rhea" id="RHEA:20780"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2 9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3157"/>
    <dbReference type="EnsemblBacteria" id="ADD42828">
        <property type="protein sequence ID" value="ADD42828"/>
        <property type="gene ID" value="Snas_3157"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3157"/>
    <dbReference type="eggNOG" id="COG0194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001715_1_1_11"/>
    <dbReference type="OMA" id="EWAVVHG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:guanylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="10">
        <location>
            <begin position="11"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="18"/>
            <end position="25"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD42828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="209" mass="23205" checksum="2299F354F43B6B81" modified="2010-04-20" version="1">MSFDDHRPVAARLTVLSGPSGVGKGSVKALIRERYPWVWFSVSATTRAPRPDEIPGFHYHYYDRAHFEKLAADGMFLEWAQYANNLYGTPRGPIEERLDAGLPAVTEADLQGARQIRQAMPQARLVFLAPPSWDELVRRLTGRGTEDAETIKRRLALAEAELSAESEFDYTITNYSVEQATEELVGLLGSPTQPTEACPVGKTLAATHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBI1</accession>
    <name>D3QBI1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018434.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3193"/>
    <dbReference type="EnsemblBacteria" id="ADD42863">
        <property type="protein sequence ID" value="ADD42863"/>
        <property type="gene ID" value="Snas_3193"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3193"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_36_3_11"/>
    <dbReference type="OMA" id="WIACATS"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="156" mass="17337" checksum="68D6E680223CFE78" modified="2010-04-20" version="1">MNDIIVRPARLSDLDGWIACATSLFREDGGTRDSSMNLDWPRDHGPDSFRAGLDDDTRLQLVAVDGHDVVGYLAGAVAEPTVMRSVRIATLRSLYVLPQHRDSGVGAVLVDRFRQWARQREADRVAVTAYASNEGALRFYQRQGLVPFHVTLEADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBL1</accession>
    <name>D3QBL1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018464.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3223"/>
    <dbReference type="EnsemblBacteria" id="ADD42893">
        <property type="protein sequence ID" value="ADD42893"/>
        <property type="gene ID" value="Snas_3223"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3223"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_2_11"/>
    <dbReference type="OMA" id="QESIRHF"/>
    <dbReference type="OrthoDB" id="1377545at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="31711" checksum="83B7AA67093B416B" modified="2010-04-20" version="1">MTTFNASSIGSQAGRTFVVTGANSGIGRIAAKVLAERDARVVLAVRDEAKGRAAAATMTGQVEVKRLDLADLASVRAFAEDFTDPIDVLVNNAGVMIPPLTRTADGFELQFGTNHLGHFALTNLLLPQVRDRVVTVASMAHHGGAIDFDDLNWQRKPYRAMRAYGQSKLANLLFTTELQRRLSQAGSSVIATAAHPGFAATNLLRPGRSRLLHTVSKAVTRVVAQSEAAGALPTLYAAVTDVPGDSYAGPKGLFETRGAPKLVGRSAAAKDAEVAKRLWEVSQELTAVVFPRQSLPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBT8</accession>
    <name>D3QBT8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
            <shortName evidence="7">EPSP synthase</shortName>
            <shortName evidence="7">EPSPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aroA</name>
        <name evidence="9" type="ordered locus">Snas_5192</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020398.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5192"/>
    <dbReference type="EnsemblBacteria" id="ADD44827">
        <property type="protein sequence ID" value="ADD44827"/>
        <property type="gene ID" value="Snas_5192"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5192"/>
    <dbReference type="eggNOG" id="COG0128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024321_0_0_11"/>
    <dbReference type="OMA" id="YEDHRMA"/>
    <dbReference type="OrthoDB" id="533829at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00104">
        <property type="entry name" value="EPSP_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="16"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="31"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate" evidence="7">
        <location>
            <begin position="98"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="173"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="431" mass="44952" checksum="6801AE346E06630B" modified="2010-04-20" version="1">MNDTRAPEELRWPAPQAPGAVRGRVSIPGSKSMMSRVLVLTAASHGASSVAAPLLARDSALMVAGLQAMGIRVVTTDDALWMVHPRAPQGPAAVDCGLAGTVMRFLPPLAAVAHGPITFDGDPYARKRPMAPLLRALTALGVSVDAASESLPFTIQGTGRISGGEITIDASSSSQFLSGLLLSAPRYDRGIVLRHQGPPVPSRPHVRMTVDMLRAAGAAVDDSRPNVWEVEPGQLGGRAWHVEPDLSNAAPFLAAALVTGGEVTVPDWPATTSQPGDLLRDLFTQLGGRAVLSHDGLTITGSGSVRGIDADLSEAGELTPVVAAVCALADSPSTLRGIGHLRGHETDRLAALTAELNRLGGDVTETDDGLRIRPRPLHGSVVDTYDDHRMAQAAAVLGLAVPDVVLSDVACTSKTLPQFPQLWTELVGARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTZ3</accession>
    <name>D3PTZ3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015322.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0029"/>
    <dbReference type="EnsemblBacteria" id="ADD39751">
        <property type="protein sequence ID" value="ADD39751"/>
        <property type="gene ID" value="Snas_0029"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0029"/>
    <dbReference type="eggNOG" id="COG1357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029034_1_0_11"/>
    <dbReference type="OMA" id="QHILERH"/>
    <dbReference type="OrthoDB" id="1101927at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13576">
        <property type="entry name" value="Pentapeptide_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="300" mass="33783" checksum="CE0E7D0D782647B1" modified="2010-04-20" version="1">MNELKPRAFWWAAAVGVLLTTVVATTLSTIALASGNTETAQLWIDIVTRSLTVTAGLGGAFALWLAFRRQRHTERDAVNRRTTELRIQAIEQLGSDKPIVRIGGLHNLEALAQGNSGLQEIVLEEICTYLRMPFYEPHDTENYDIKELWGVTQEREARRTAQHILERHLKPDGPYEYWDHDQLNLRQAALNDLNLRGCRLNNADFAAAELGGITDFRDAAFRGDTTSFTMTEFDAAWFDNALFTAVARFHDTIFTQPPNFTGAAATRDDSVEHVWPNGWHLDPNSDSTGFHQITKDELAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU87</accession>
    <name>D3PU87_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1324</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016604.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1324"/>
    <dbReference type="EnsemblBacteria" id="ADD41033">
        <property type="protein sequence ID" value="ADD41033"/>
        <property type="gene ID" value="Snas_1324"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1324"/>
    <dbReference type="eggNOG" id="COG3207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_308997_0_0_11"/>
    <dbReference type="OMA" id="RRWCEAT"/>
    <dbReference type="OrthoDB" id="143206at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007817">
        <property type="entry name" value="Isocyanide_synthase_DIT1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05141">
        <property type="entry name" value="DIT1_PvcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="853" mass="93371" checksum="99FEAFF9A5F415B6" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUA1</accession>
    <name>D3PUA1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016618.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1339"/>
    <dbReference type="EnsemblBacteria" id="ADD41047">
        <property type="protein sequence ID" value="ADD41047"/>
        <property type="gene ID" value="Snas_1339"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1339"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_6_11"/>
    <dbReference type="OMA" id="GLHLITF"/>
    <dbReference type="OrthoDB" id="1616572at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="274" mass="29253" checksum="9F7A771676EDAB82" modified="2010-04-20" version="1">MTFLVTGATGNVGRHIVEQLVAAGAPTRALTRNPAKANLPAEAEVIAGDLTRTDTLAAAFEGVTAAHFINFGGDNYELLSNGQEIVDLALKAGVKRVTLLGAWDNGSLEDAVDASTLQWTRVGPGEFMSNALGWAEAIRTTGVVEEPFPDGHSPMSHEADIAAVAVKALLEEGHHGKTIQVAGPSAVSLRDKIRIIGEAIGKDIKLVELTPEQTREREAANGISQELIDFKINVFGSLPTEPYPLEGAAEFEKFTGKKPRDFKQWAAENADAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUJ2</accession>
    <name>D3PUJ2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD linked oxidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3339</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018576.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3339"/>
    <dbReference type="EnsemblBacteria" id="ADD43005">
        <property type="protein sequence ID" value="ADD43005"/>
        <property type="gene ID" value="Snas_3339"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3339"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_10_0_11"/>
    <dbReference type="OMA" id="FPQRSSH"/>
    <dbReference type="OrthoDB" id="330793at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="33"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="448" mass="48172" checksum="4892AACCD043B626" modified="2010-04-20" version="1">MTNSTRTELSDGDLIKPGDAAYDEARTVWNAMVDRRPRAIVRCRDAAEVAAAVRYAREHDLEIGVRCGGHSIVGHAVPDGGLMIDLRSMSAVSVDPSRRIAHVQGGAMLGALDAAAQRHGLATTAGNVSHTGVGGLTLGGGMGWLARKYGLTCDNVESYELVTATGALIRASRDENPELFWGLRGGGGNFGIVTRFEFRLHPVGTRALLADFTFPLSSAGRVLRAWRDLSLDAPREATFTAAVADSADGPRVTAGLVWVGDPDRARGFLPTMRALGKPSSHRVEELSYLRLQSMDDSVEGHAVRRYWKGHYFADFTDAAVEALWRRGTQDGHGQHLPSVSLQSYGGAIADVADADSAFSHRDARFEFVGASRWLDPSEDTSRIAAARRCGAALDQFASGAYVNTLGDDGAAGVRRAFPADKLARLTALKDTYDPDNVFHLNQNIRPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUK7</accession>
    <name>D3PUK7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3355</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018591.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3355"/>
    <dbReference type="EnsemblBacteria" id="ADD43020">
        <property type="protein sequence ID" value="ADD43020"/>
        <property type="gene ID" value="Snas_3355"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3355"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_23_0_11"/>
    <dbReference type="OMA" id="VQTTVAY"/>
    <dbReference type="OrthoDB" id="1210653at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="1"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="394"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="409" mass="42498" checksum="28A1146C4A157571" modified="2010-04-20" version="1">MTTGLTTRRRVLLAIVCAVAVSTIYGIQPVLEAAGRDLGMNPAALGWLVASGQIGYLAGLVLLVPLGDLLNRRRLITTHLVLIALGAAITAIAPTAAIAIAGLALAGLFAVVVQTTVAYVAAVSPPRQRGRDIGAVTSGVVIGILGVRVAAGSLADLADWRAVYLVLTGLSVLLAFATATILDADHPRPQTRYPRLLASLAHLAATDRLLRNRGLVAFFLFASFGTLWSGLALPLTEAPWHLTTSHIGLFGLAGLTGALGAARAGRWADRGLTTRVTIWSLGLLIASWLLIAQTGSSLWPLIVGIIALDFAVQAVHVSNQHLLTTAHPERSSTVIGAYMAFYSLGSALGAITTTWAYSLAGWPAASLLGAAYAALALLVAAALHQTPTRPHAKPADGNHTRAETARCSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUP2</accession>
    <name>D3PUP2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018626.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43055">
        <property type="protein sequence ID" value="ADD43055"/>
        <property type="gene ID" value="Snas_3391"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3391"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_2_3_11"/>
    <dbReference type="OMA" id="YTYAFTT"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048369" evidence="1">
        <location>
            <begin position="25"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="45"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="420" mass="45503" checksum="6D6CAA9036C193A6" modified="2010-04-20" version="1">MRKQVFIAAAVAAVLVTGSAVALADPFDAGSGSDKSTLNNDLLNQKIEALHEAGAPGVIAEVRDGDGVWEGSAGERVIGDNKKPDPTDRVRVASLTKSMIATVTLQLADEGEVDLDAPIDEYLPDVLRYEETITVRQLLNHTSGLRDYFVHIYGSLHNGDPSDVRTNRLNKYTPKEIIGMATEEPLLFEPGTKFSYANTGYTVIGLLIEKLTGKSIQDAVDERVLEPAGMNDSYLAKEGQLIVDGPHPNGYFDNGDGTEMIDVSDIDPSQFWSGVAAVSSPRDINRFYRAMSDGTLLTPERLAEARDLTPQSDKTYGLGLDSFKVPDNCAPVPSKAAYGHTGDGLGYITFSGSSPDGERQVTFAFTLGYELNPTVTEKLRKAWRGLFYAGLCDIDTDKPTVAKTLPDEDPLSLQATFRQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUT4</accession>
    <name>D3PUT4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribonuclease BN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5324</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020529.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5324"/>
    <dbReference type="EnsemblBacteria" id="ADD44958">
        <property type="protein sequence ID" value="ADD44958"/>
        <property type="gene ID" value="Snas_5324"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5324"/>
    <dbReference type="eggNOG" id="COG1295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045539_3_1_11"/>
    <dbReference type="OMA" id="KQPKFRW"/>
    <dbReference type="OrthoDB" id="1421045at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035875">
        <property type="entry name" value="RNase_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00765">
        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="301" mass="31380" checksum="5EDBA06556B11D1C" modified="2010-04-20" version="1">MSGITPHSGTLKRTIKEFNADNLTDAAAALTYYGVLSIFPGLLVLASLMGLFGQSATTSMKDVTAVAPGPVRDILTDATTGVAAQPATAGVMAIVGLLAALWAASGYIGAFMRASNVVYDVPEGRPIWKTLPLRLAVTICVGVLLVASALIVVLTGQLAGTVGELLGVGATAVTVWDIAKWPVLVVLVALIFSILYWASPNAKVGGPLRQAPGGLVAVGLWLVASAGFAFYVANFASYNKTYGTLGGIIVFFIWLWVSNLAILFGAELNAELERGRAIKAGVPETAEPYVELRDTRSVPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV01</accession>
    <name>D3PV01_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5393"/>
    <dbReference type="EnsemblBacteria" id="ADD45025">
        <property type="protein sequence ID" value="ADD45025"/>
        <property type="gene ID" value="Snas_5393"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5393"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_5_3_11"/>
    <dbReference type="OMA" id="EHMAKLC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="120" mass="12431" checksum="0564E73ED3808475" modified="2010-04-20" version="1">MTAEIEAGIAPAAALFHSLSDETRLRIVQYLAAGEARVVDLTEQLGLAQSTVSKHLACLRDCGLVASRAEGRQAFYSLSRPELMDLLSAAEGVLAATGHAVAVCPTHGIKASGDATVEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVD5</accession>
    <name>D3PVD5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase, WecB/TagA/CpsF family</fullName>
            <ecNumber evidence="2">2.4.1.187</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.187" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016759.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1484"/>
    <dbReference type="CAZy" id="GT26">
        <property type="family name" value="Glycosyltransferase Family 26"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41188">
        <property type="protein sequence ID" value="ADD41188"/>
        <property type="gene ID" value="Snas_1484"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1484"/>
    <dbReference type="eggNOG" id="COG1922">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063203_0_1_11"/>
    <dbReference type="OMA" id="NMNGTDF"/>
    <dbReference type="OrthoDB" id="1759731at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047244">
        <property type="term" value="F:N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06533">
        <property type="entry name" value="Glyco_transf_WecG_TagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004629">
        <property type="entry name" value="WecG_TagA_CpsF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34136">
        <property type="entry name" value="PTHR34136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03808">
        <property type="entry name" value="Glyco_tran_WecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00696">
        <property type="entry name" value="wecG_tagA_cpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="251" mass="27252" checksum="A7329A31230DA2DC" modified="2010-04-20" version="1">MDVGGIRFDALTSGEVIDLVGEAWLAGRGGRIVTPNVDIVRQTRRVPEARAHVRGADLVVADGAPLIWASRLSGRPLPERVAGSDLVWSLSQAAAGHGRRVFLLGGDPVRDTAGQAAARLRERYPDLTVAGACSPPMGFDRDEAAMRSLVAELCEAKPDIVFVGLGFPKQERLIARLAPYLPAAWFLGCGAGIDFVAGAKRRAPHWMRRSGLEWLHRLGSEPRRLFVRYVLHDIPAACGLLLRSGATRLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVE8</accession>
    <name>D3PVE8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018633.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3398"/>
    <dbReference type="ESTHER" id="stanl-d3pve8">
        <property type="family name" value="Haloacetate_dehalogenase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43062">
        <property type="protein sequence ID" value="ADD43062"/>
        <property type="gene ID" value="Snas_3398"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3398"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_1_11"/>
    <dbReference type="OMA" id="LPTLDMW"/>
    <dbReference type="OrthoDB" id="1439833at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="30"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="292" mass="31321" checksum="53A3169F1843A58D" modified="2010-04-20" version="1">MTITIPGFDTKAIDVADGVSLNAAVGGDGPAIILLHGFPQTHLMWRHVAPVLAEHHTVIAPDLRGYGASAKPAALDPDTYSKRTMAADIVGLADALGIDRFTLVGHDRGAHVAFRAGLDHPNRVSQLGILDILPTLDTWNVLQGVNAAVAFHLYLMAQPVGLPEQMIANSSDAFFGFFLDAWNTGPDAIPADVRAEYLNASRQAVDSIVADVRATATIDIEHDQADLDAGNRLAMPVTVIQQDWGQQLGFDAAATWRPWAADLEHFTTRAGHFMAETAPDDIATLILNLAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW99</accession>
    <name>D3PW99_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class II aldolase/adducin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016827.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1553"/>
    <dbReference type="EnsemblBacteria" id="ADD41256">
        <property type="protein sequence ID" value="ADD41256"/>
        <property type="gene ID" value="Snas_1553"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1553"/>
    <dbReference type="eggNOG" id="COG0235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006033_3_2_11"/>
    <dbReference type="OMA" id="ACNAIEE"/>
    <dbReference type="OrthoDB" id="599627at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="5"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="204" mass="21471" checksum="DB22B58DF7693E76" modified="2010-04-20" version="1">MSPHDELVAVARSIFDRGLTHARTGNVSIRHGGDILVTPTGVSLGAVTADSLSLIDARGRHLDGPKPTKEAFLHAALLRARPDAGAVVHTHSTHAAAVSCLDGLDSADALPPLTAYFAMRVGRLPLLPYFAPGDTGLEPAAETAARDHAALLLRNHGPNVAGKDPATTLDALEELEETAKLFLLLRGSRTRPLTPQQRDALTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWA3</accession>
    <name>D3PWA3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydroxypyruvate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1557</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the hyi family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.22" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016831.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1557"/>
    <dbReference type="EnsemblBacteria" id="ADD41260">
        <property type="protein sequence ID" value="ADD41260"/>
        <property type="gene ID" value="Snas_1557"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1557"/>
    <dbReference type="eggNOG" id="COG3622">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050006_1_2_11"/>
    <dbReference type="OMA" id="YVQYDIY"/>
    <dbReference type="OrthoDB" id="1007505at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008903">
        <property type="term" value="F:hydroxypyruvate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026040">
        <property type="entry name" value="HyI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006241">
        <property type="entry name" value="HyI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="3">
        <location>
            <begin position="25"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="264" mass="28552" checksum="D2F50C6E38C76BB2" modified="2010-04-20" version="1">MTEPAFRFDANLKWLFTELPFEERFDAAAAAGFEGVEYASPYDHEPAVLSKLLTDAGLTQVLINTPMGPPGSATRSGLACLPDAVAEFRDGVERGLEYATALNAAFLHVVGGLRPEGVSRDRAFARYVANIGWAAERARSAGVRLLLEAQNKRDAPRFILDTQEQAAAVAEAVGAETVGVLFDFYHAQIDEGDLITTLDRVRPWVSHLQIADPPSRHEPGTGEIGWPAIFAHLAATGYDGWIGCEYAPATTTVAGLGWMKEYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWB7</accession>
    <name>D3PWB7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cobalt ABC transporter, inner membrane subunit CbiQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1571</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016845.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1571"/>
    <dbReference type="EnsemblBacteria" id="ADD41274">
        <property type="protein sequence ID" value="ADD41274"/>
        <property type="gene ID" value="Snas_1571"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1571"/>
    <dbReference type="eggNOG" id="COG0619">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056469_1_2_11"/>
    <dbReference type="OMA" id="IASFMIR"/>
    <dbReference type="OrthoDB" id="1479665at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006824">
        <property type="term" value="P:cobalt ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012809">
        <property type="entry name" value="ECF_CbiQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02454">
        <property type="entry name" value="ECF_T_CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="252" mass="27044" checksum="0E80AF61AB6FCD7F" modified="2010-04-20" version="1">MGAGHALYRPGTTPVHRLPGEVKIAASVTFTIAVVATPRQAVWAFGCYALLLLAVMAVARITPLWLAKRSLIEVPFVALAVLLPFMEGGPYTTWLGLEVSVPGSWGAWNILAKATLGVWASLTLAATTDVTALLAGLNRLRCPAVITQLATFMVRYTHVLASEARRMRVARISRGDNPRFLWQLKGFATGVGVLFLRSFERGERVYVAMLSRGYNGQMPLGSELRAAAVTDWARAALLPVAAGAIAATAIML</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWG8</accession>
    <name>D3PWG8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_3528</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018761.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3528"/>
    <dbReference type="EnsemblBacteria" id="ADD43190">
        <property type="protein sequence ID" value="ADD43190"/>
        <property type="gene ID" value="Snas_3528"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3528"/>
    <dbReference type="eggNOG" id="COG0609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013016_1_0_11"/>
    <dbReference type="OMA" id="MDQFRFW"/>
    <dbReference type="OrthoDB" id="1283908at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048421" evidence="8">
        <location>
            <begin position="31"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD43190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="336" mass="33972" checksum="2363065CC71341BD" modified="2010-04-20" version="1">MPRPARRRATVTVVAVVALVCVTILSLSVGARDLSPSEVVGALLWPDDSVEATVVIEKRLPRTLVGLLVGAGLAAAGVIMQALTRNPLADPRIFGVSAGASLGVVVAIAGFGLASLSQYVWFGIAGALAAGLVGFMIAHTVSRGREGSSPVTLALVGTALDASLSAVIYGVLTTSAQSFDQYRFWVVGSLAGRDAAVAWQVSPFLVAGLVVAAVIARGLDALVLGEEMASGLGHRTGIVRFAGAVAVALLTGAAVAAAGPVGFIGLAIPHLVRLLVGHDHRPVLLVSMLLGPVLLLAADVLGRRITAGEMPAGIVTALVGAPVLILLVRRAKAVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWH4</accession>
    <name>D3PWH4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3534"/>
    <dbReference type="EnsemblBacteria" id="ADD43196">
        <property type="protein sequence ID" value="ADD43196"/>
        <property type="gene ID" value="Snas_3534"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3534"/>
    <dbReference type="HOGENOM" id="CLU_1000797_0_0_11"/>
    <dbReference type="OMA" id="GAYWSAY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="278" mass="28840" checksum="A9E92603E3C2D73D" modified="2010-04-20" version="1">MLSSATRQWLRGTGSRGPLSGAQWAGALGLAAATALAAYWLMFVELTPIPPNFKIQQGFGPFQTVGAVAWLAWLVTGATAAALPKATRAMTVVSLALTIAAAPAAAWYGNTPPKLTVLLPQVALGVVALAFSTAPGRFARLLPAAGGTVALIAGVVTAAWLNPTFYNYIESDRSVLQAVGLLLLAVGLGFTLLDFASRRGSRGLWTLLLLTAPALLCATRQLETAASIDLRTGAVDYSGMWLPIVTTASAVTGVSIGILLVAVLMHVRADRARAKFDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWL7</accession>
    <name>D3PWL7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3577</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018810.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3577"/>
    <dbReference type="EnsemblBacteria" id="ADD43239">
        <property type="protein sequence ID" value="ADD43239"/>
        <property type="gene ID" value="Snas_3577"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3577"/>
    <dbReference type="HOGENOM" id="CLU_2169525_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="110" mass="12535" checksum="48ABDBB4E90C61EC" modified="2010-04-20" version="1">MTVHALHRAADLIEQRGWTRGGYCYPDAEGYCMDKALLAVCGLCTACENKHDLTDEYRDALAALRAALNVATCWDLWWWNDNSRRTKSDVVRLLRRAADHAPARRKSLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWU3</accession>
    <name>D3PWU3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5536</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in DNA recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RmuC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020738.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5536"/>
    <dbReference type="EnsemblBacteria" id="ADD45167">
        <property type="protein sequence ID" value="ADD45167"/>
        <property type="gene ID" value="Snas_5536"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5536"/>
    <dbReference type="eggNOG" id="COG1322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024057_1_1_11"/>
    <dbReference type="OMA" id="GDSKMQG"/>
    <dbReference type="OrthoDB" id="1309809at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003798">
        <property type="entry name" value="DNA_recombination_RmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30563">
        <property type="entry name" value="PTHR30563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02646">
        <property type="entry name" value="RmuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="378" mass="41539" checksum="2F8CC617FEC5CD7E" modified="2010-04-20" version="1">MDYVLIAIVCLAAGAAAGWFAARARSATENAALSARLDAARDNETRLEQSLRAVTADATAQSKTALNELLHPLRESLHRYEQHVGEVERARLAAYTELRTQVSRMSDTSDALRTQTGQLLSALRTPQVRGRWGEHQLRRIVEASGMLEHCDFTEQTTASIEDQTVRPDLVVKLAGGKHVVVDAKAPFNAYLDALETADETVRDGQLDMHAKQLRAHVNQLSKKEYWRAFDSTPEFVVLFVPADTFLDAALKRDPNLLEYAFARDIVLATPATLIALLRTIAYSWRQEALAKGAAQVHALGKEMYSRLATMGGHLSKLGTSLSGAVTAYNATLGSLESRVMVSARKFAELGISSEELPEMDQIEVTARQVQHEALRSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWW1</accession>
    <name>D3PWW1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020756.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5554"/>
    <dbReference type="EnsemblBacteria" id="ADD45185">
        <property type="protein sequence ID" value="ADD45185"/>
        <property type="gene ID" value="Snas_5554"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5554"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019122_0_1_11"/>
    <dbReference type="OMA" id="LDRRQTY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="542"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="594"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="625"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="663" mass="69010" checksum="EC84F7050E13C9A6" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX12</accession>
    <name>D3PX12_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5606</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020807.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5606"/>
    <dbReference type="EnsemblBacteria" id="ADD45236">
        <property type="protein sequence ID" value="ADD45236"/>
        <property type="gene ID" value="Snas_5606"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5606"/>
    <dbReference type="eggNOG" id="COG1116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="AMTREYM"/>
    <dbReference type="OrthoDB" id="1832232at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="264" mass="28890" checksum="144F230C62AAB613" modified="2010-04-20" version="1">MIEIRGLTKSFTGQDGGVVEALRDVDLDVAENEFLTVLGPSGCGKTTLLKIVAGLITPDGGRISIHGEPVRGPGEDRAMVFQNFALLPWATVLDNVAFGLKMRGTGKAEREERARELIATVGLSGFETKRPGELSGGMQQRVGIARALAVRPRVLLMDEPFGAVDEQTRRLLQEELLSIWEESRLTVVFITHSMEEAVLLGDRVVLMSARPGQVSEIVPVPLERPRSSDVGGLERSPEYAELSAYLWDRLRGMHAEHRPAKVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX85</accession>
    <name>D3PX85_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1992 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016919.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1645"/>
    <dbReference type="EnsemblBacteria" id="ADD41348">
        <property type="protein sequence ID" value="ADD41348"/>
        <property type="gene ID" value="Snas_1645"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1645"/>
    <dbReference type="eggNOG" id="ENOG50318KY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109304_1_0_11"/>
    <dbReference type="OMA" id="MTERKPP"/>
    <dbReference type="OrthoDB" id="1950808at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018961">
        <property type="entry name" value="DnaJ_homolog_subfam-C_membr-28"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09350">
        <property type="entry name" value="DUF1992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1992" evidence="2">
        <location>
            <begin position="9"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="128" mass="14291" checksum="953A853324D9DDD4" modified="2010-04-20" version="1">MDGRIEQRIEREIRQATERGDFENLPGAGKPLPGAGEHLPEDWWLREKMRRESAGASVLPTTLRLRKEAQGIGETVAKLRTEAEVRQAVAELNDQIRKAQLGPVDGPPVPLRTVDVGAVLRDWHSKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX86</accession>
    <name>D3PX86_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1646</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016920.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1646"/>
    <dbReference type="EnsemblBacteria" id="ADD41349">
        <property type="protein sequence ID" value="ADD41349"/>
        <property type="gene ID" value="Snas_1646"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1646"/>
    <dbReference type="eggNOG" id="ENOG502ZS7I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1862915_0_0_11"/>
    <dbReference type="OMA" id="GAWVYPG"/>
    <dbReference type="OrthoDB" id="1705294at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="144" mass="15823" checksum="ECC15FF94EC75EED" modified="2010-04-20" version="1">MNEQTIPPPDAELHALDRLVGIWRISGGAEGTTSFRWMEGGRFLIQEGELSRDGREFKVLEIIGREKPWGAKEPGSQIKSRAYTDLGDTLDYVYEVDGEVVTVWAGAKGSPTFCKITVSPDGQTMTSGWEWPGGGYKAEATRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXB8</accession>
    <name>D3PXB8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell envelope-related transcriptional attenuator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1681</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1681"/>
    <dbReference type="EnsemblBacteria" id="ADD41381">
        <property type="protein sequence ID" value="ADD41381"/>
        <property type="gene ID" value="Snas_1681"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1681"/>
    <dbReference type="eggNOG" id="COG1316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016455_0_2_11"/>
    <dbReference type="OMA" id="IMIMHIN"/>
    <dbReference type="OrthoDB" id="491753at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="3">
        <location>
            <begin position="90"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="357" mass="39065" checksum="CFC00C1FC7E88325" modified="2010-04-20" version="1">MAGRRRSSTAKRGNKAPLWAKFMVGIGAILLVTSIGGVTFGIDMISRINSIGSADTGIAQDEDGKITEGPLNILLVGADLRVKKNNTPLADTIMIMHINKSLTKANIVSIPRDLKVPMEGGGNCTTGECMDKINSSYTLGFNKRNKPEDGLTNLRKVLTDYTGIKFQANGLVNFEGFLDVVKTFGGIELCLDHDLDTAHGGFYKKGCRQYKPDDALAIVRERYAWPDGDYGRQRMQQHFVKQLLKEAMKRGYAKNPGKLGDLIDQIGSQMRMDLGGVKPVDYAIALRGIKADKMKTVKLPSGTSEEIVNGTKISYVVVGEDQQQDAQGLFEAIKGDTLDDWIESNPDYLNQDPKDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXG7</accession>
    <name>D3PXG7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1732</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1732"/>
    <dbReference type="EnsemblBacteria" id="ADD41430">
        <property type="protein sequence ID" value="ADD41430"/>
        <property type="gene ID" value="Snas_1732"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1732"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049869_0_0_11"/>
    <dbReference type="OMA" id="RWATWTA"/>
    <dbReference type="OrthoDB" id="1397635at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="362" mass="38890" checksum="CBBE918AA53D00BB" modified="2010-04-20" version="1">MAVPAVGPEAWGMRRNWPQWIGYLTALVSFGYGVLGLYWSLGGAGFPFGVGDPTMVESGRDAIAGNLLGFATPEPTGAVFAVAGLLGAILALLLTRGVGRGPARIAFITAALVIAFALTIVIQDYRPLIVVAYTPILTVSKLLFGWPEGVGFGDLYQWPSLNLLILQLLGIAWILTALAYKRRTADACGNCGRDGHGTGSRLVQWGKPAVVVAVVTPLIYCTTRWLWALGFTLGIDAEWYREGQENGLWLAGAALASLGALGAVLTLGLIQRWGEVFPRWMIGLRGKRVPPMLAVVPATVVAMLVTSAGSMYIRMAFVMGVEDKWVTNMPETLWPVWGAALFVAALSYHRRRRLACGVCGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXP8</accession>
    <name>D3PXP8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome bd ubiquinol oxidase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Snas_3721</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018949.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3721"/>
    <dbReference type="EnsemblBacteria" id="ADD43378">
        <property type="protein sequence ID" value="ADD43378"/>
        <property type="gene ID" value="Snas_3721"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3721"/>
    <dbReference type="eggNOG" id="COG1271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030555_3_3_11"/>
    <dbReference type="OMA" id="FLINIAM"/>
    <dbReference type="OrthoDB" id="271551at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="426"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD43378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="463" mass="50765" checksum="F56230E276597034" modified="2010-04-20" version="1">MDVLDASRWQFAITTVYHFLFVPLTIGLSFLVAGMQSAWVRTNDERWLKLTKLFGKLFLINFAMGVVTGIVQEFQFGMNWSAYSTYVGDVFGAPLAIEGLAAFFLESTFLGLWIFGWDKLPRRVHLACIWIAAFGTALSAYFILVANSFMQWPTGHTLNNDRVELVDFAALLGNKVALITLPHTLAAVFLTSGAFMLAVAMWHLMRHHRGDDTQSPTDTDPTAEKAWRSAAKIGAVTVLVASVAVVVTGDIQGKIMTETQPMKMAAAEALYETEQPAAFSILTIGSLDGTEEVWSITVPGLLSFLGTGSFDGEVLGINDVNASYQDKYGPGDYRPNIPLTYWSFRAMIGLGIAATGVALLALWTLRRGRTPSNRWLRRLMVVSPLLPLAATAFGWIFTETGRQPWIVFTLLKTEDGVSPSVSFAEIMTSLIGFTTLYAVLAVVEIGLLLRYAKAGLPTEPATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXQ6</accession>
    <name>D3PXQ6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dynamin_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3729</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018957.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3729"/>
    <dbReference type="EnsemblBacteria" id="ADD43386">
        <property type="protein sequence ID" value="ADD43386"/>
        <property type="gene ID" value="Snas_3729"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3729"/>
    <dbReference type="eggNOG" id="COG0699">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028675_0_0_11"/>
    <dbReference type="OMA" id="LATAQCD"/>
    <dbReference type="OrthoDB" id="152800at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="495"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Dynamin_N" evidence="2">
        <location>
            <begin position="60"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="626" mass="68354" checksum="AC005C3617A504D6" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXX3</accession>
    <name>D3PXX3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">UDP-N-acetylglucosamine--lysosomal-enzyme N-acetylglucosamine phosphotransferase</fullName>
            <ecNumber evidence="8">2.7.8.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5672</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the stealth family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.17" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5672"/>
    <dbReference type="EnsemblBacteria" id="ADD45302">
        <property type="protein sequence ID" value="ADD45302"/>
        <property type="gene ID" value="Snas_5672"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5672"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033996_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003976">
        <property type="term" value="F:UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031358">
        <property type="entry name" value="Stealth_CR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021520">
        <property type="entry name" value="Stealth_CR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031357">
        <property type="entry name" value="Stealth_CR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031356">
        <property type="entry name" value="Stealth_CR4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17101">
        <property type="entry name" value="Stealth_CR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11380">
        <property type="entry name" value="Stealth_CR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17102">
        <property type="entry name" value="Stealth_CR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17103">
        <property type="entry name" value="Stealth_CR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0270">Exopolysaccharide synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Stealth_CR1" evidence="5">
        <location>
            <begin position="281"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Stealth_CR2" evidence="4">
        <location>
            <begin position="322"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Stealth_CR3" evidence="6">
        <location>
            <begin position="473"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="Stealth_CR4" evidence="7">
        <location>
            <begin position="548"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="593" mass="66741" checksum="1A712A47EFEE380C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY08</accession>
    <name>D3PY08_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aminotransferase class IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020908.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5707"/>
    <dbReference type="EnsemblBacteria" id="ADD45337">
        <property type="protein sequence ID" value="ADD45337"/>
        <property type="gene ID" value="Snas_5707"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5707"/>
    <dbReference type="eggNOG" id="COG0115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020844_1_0_11"/>
    <dbReference type="OMA" id="RCHIKST"/>
    <dbReference type="OrthoDB" id="1275805at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="281" mass="30218" checksum="F36EC7C837633918" modified="2010-04-20" version="1">MAQVVAVLGKGVVDPSQPILLADDLGPVRGDGLFETINVRQGVAWQLEPHLERMARSAAKMDIELPSLASIRELCEQALTAFGTESEGALRLICTRGLETGSAPTLWATLNPVPDSQRNARRDGLKLLELSLGYPADARARSPWLLGGAKTTSYAVTMSAIRYAQSKGYDDALWTSEDGYLLEGPTSTLVWLNGETLYTVPSDTGILIGTTAAFLFENAHELGLKVGEERIRPADLTAVDGAWMTSSVRGVAPVRSLDNVELNQSPRTAELQKLAGFPTPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY11</accession>
    <name>D3PY11_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020911.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5710"/>
    <dbReference type="EnsemblBacteria" id="ADD45340">
        <property type="protein sequence ID" value="ADD45340"/>
        <property type="gene ID" value="Snas_5710"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5710"/>
    <dbReference type="eggNOG" id="COG1502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_705777_0_0_11"/>
    <dbReference type="OrthoDB" id="1881748at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048071" evidence="1">
        <location>
            <begin position="39"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="322"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="391" mass="42414" checksum="042107FE657A002D" modified="2010-04-20" version="1">MRLRRLNHSSRTKRTLIYASALAVVAAGTVGATTYAQADASTRAGGCTASGAYEVCFNDPAGGSDPLIETRLRELTRSAESGDSIRVSLYTWTRAELANDLVAAKKRGVDVKVVLDGHNKTDGNAGYTVLRDGGVPVTSCSDNGCIGSNVNHNKLYLFNIDGVKQSVLSSANLSTAQTGWYNNLIRITDSGLYDYYQGYWNRMNAQSWTYDGVTWHDDDKVGYGSSTATKAYVYPRGTDNVLGVLGNVTKCSTDGNGDGNSDRKIWVAQSLFTQARESVRNKLADLQDMGCDVRIVVADGTTEKWVQSSNSGGNLSDAKVGTVTNTHNKLILIDAYYAGKWQDVVFTGSHNLTGTSLDTNDEALVRVTDYFVFKEYRVYFDKLFGLASGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY25</accession>
    <name>D3PY25_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5724</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5724"/>
    <dbReference type="ESTHER" id="stanl-d3py25">
        <property type="family name" value="A85-Feruloyl-Esterase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45354">
        <property type="protein sequence ID" value="ADD45354"/>
        <property type="gene ID" value="Snas_5724"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5724"/>
    <dbReference type="eggNOG" id="COG2382">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037618_0_1_11"/>
    <dbReference type="OMA" id="YFEYCYL"/>
    <dbReference type="OrthoDB" id="1828423at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="342" mass="38309" checksum="C01CD15366A93D2D" modified="2010-04-20" version="1">MASLKLAGRMNEHVVESELLRDNVLGDPAERPLWVYTPPGYDDGDETYPVCYLLLGYAGTLPMWRNRTPFRKPVPELFDAMVASGEAPPMILVFVDAWTSYGGSQFVDSVGTGRYHSYLCEEVVAWVDRHYRTRADREYRAIAGKSSGGLGAAISAMLRPDLFGAFATHSGDSLSEAQYIPHFLHAARQLRPYGGDIFAWWADFGSRVAFTKDEDLRLLELLGVSACFSPDPDGKPLLPFDPVTGALVEDVWRRWLEWDPVRMARGYAEALRSQKGIWIDAGTRDEWFLDLGATAFRRVLGDIGVADDVVEFELFDAGHVGIEYRHPLALSWLARRLTDQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY68</accession>
    <name>D3PY68_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5767"/>
    <dbReference type="EnsemblBacteria" id="ADD45397">
        <property type="protein sequence ID" value="ADD45397"/>
        <property type="gene ID" value="Snas_5767"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5767"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042900_1_1_11"/>
    <dbReference type="OMA" id="PIPTDGY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016676">
        <property type="entry name" value="P_lipid/glycerol_AcTrfase_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016753">
        <property type="entry name" value="P_lipid/glycerol_ac_tran_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="69"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="281" mass="30909" checksum="72AC048BE8E02DC0" modified="2010-04-20" version="1">MDADRVAEALEELANLFTKRMTGDYEVDEFGFDAELTEQVAFRALRPLYRKWFRVETSGLDNVPDKGAALLVGNHSGTIAMDAMMVQLALFDEHPAQRHLRLLAADFVFKSPVLGEYARKLGATLASNTDAERLLGAGEVVGVFPEGTKGIGKPYWDRYKLQRFGRGGFVSTALRTGTPIIPVSIVGAEEIYPIIGDVPVLARLLKLPYFPITPTFPLLGPLGAVPLPSKWMIDFGEPIPTEGMAHLADDPLEVFNLADRVKETIAGTLRELLKRRGPAFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYB7</accession>
    <name>D3PYB7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the arylamine N-acetyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017055.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1787"/>
    <dbReference type="EnsemblBacteria" id="ADD41484">
        <property type="protein sequence ID" value="ADD41484"/>
        <property type="gene ID" value="Snas_1787"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1787"/>
    <dbReference type="eggNOG" id="COG2162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049918_1_0_11"/>
    <dbReference type="OMA" id="WGNHIAL"/>
    <dbReference type="OrthoDB" id="1687886at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001447">
        <property type="entry name" value="Arylamine_N-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11786">
        <property type="entry name" value="PTHR11786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00797">
        <property type="entry name" value="Acetyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01543">
        <property type="entry name" value="ANATRNSFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="274" mass="31084" checksum="A5242994F58165FF" modified="2010-04-20" version="1">MNITPILDRLEQPFPTRADLKTLRGLYRAWRTHVPYENFDLQLGRDTPLDSEFLVDKFGIRRRGGTCFQMNGTLALLLRGVGFDVDIVESGVQREKRGEDVWGNHIALLVHVDGKRWLADVGIGDSFLEPLPLTEGTHRQGTLDYRLERLSDGVWRARHHAGGSVSSWDFRTVPRELSEFAENARHSTPVMHKVLVAQHHRDGHELALRSRVLTDTGPAGKTRRVLEDLADFTEALKGLAISVDDLGPDNVRLLWNKTAEQYQAWLDIEKRIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYG2</accession>
    <name>D3PYG2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017100.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1833"/>
    <dbReference type="EnsemblBacteria" id="ADD41529">
        <property type="protein sequence ID" value="ADD41529"/>
        <property type="gene ID" value="Snas_1833"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1833"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_19_3_11"/>
    <dbReference type="OMA" id="LYLYSMW"/>
    <dbReference type="OrthoDB" id="1809950at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="158" mass="17445" checksum="7F7DBFB0AD4CB6D8" modified="2010-04-20" version="1">MSDDNRVSVRGLGPEDWRIKRELRLAALKADEQWFGGNYADSAARTEQQWRDWPDGAVFAAYLDEEPVGLVAGVRPEHLDGQAELISMWVGSAGRGHGLAGLLVDAVAAWAREQGCTDLYLEVMPHNESACRAYRRSGFAEVAAPVRNAGDIAMRYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYP9</accession>
    <name>D3PYP9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Holliday junction ATP-dependent DNA helicase RuvB</fullName>
            <ecNumber evidence="6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ruvB</name>
        <name evidence="8" type="ordered locus">Snas_3826</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Forms a complex with RuvA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RuvB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019053.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3826"/>
    <dbReference type="EnsemblBacteria" id="ADD43482">
        <property type="protein sequence ID" value="ADD43482"/>
        <property type="gene ID" value="Snas_3826"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3826"/>
    <dbReference type="eggNOG" id="COG2255">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055599_1_0_11"/>
    <dbReference type="OMA" id="IHRMSRP"/>
    <dbReference type="OrthoDB" id="874197at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00016">
        <property type="entry name" value="DNA_helic_RuvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041445">
        <property type="entry name" value="AAA_lid_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004605">
        <property type="entry name" value="DNA_helicase_Holl-junc_RuvB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008824">
        <property type="entry name" value="RuvB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008823">
        <property type="entry name" value="RuvB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42848">
        <property type="entry name" value="PTHR42848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17864">
        <property type="entry name" value="AAA_lid_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05491">
        <property type="entry name" value="RuvB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05496">
        <property type="entry name" value="RuvB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00635">
        <property type="entry name" value="ruvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 6 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="61"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="69"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="359" mass="38380" checksum="649E725D52563262" modified="2010-04-20" version="1">MDEFGEEDFYEPDIVSAQAMPAEARAEAGVRPAKLEELIGQARVREQLELLLSGAQQRSAAPDHILLSGPPGLGKTTLAMIVAAELGVSLRQTSGPAIERSGDLAAVLTSLGPGDVLFIDEIHRIARPAEELLYTAMEDFRVDVMVGKGPGATAIPLDLEPFTLVGATTRSGLLTGPLRDRFGFVGQLDFYDPPELESIVHRTARILSVDITDSGAREIAGRSRGTPRIANRLLRRVRDFAQVRADGHVTQEVASAALALYDVDDIGLDRLDRAVLTALIESFGGGPVGLTTLAVAVGEEPDTVEEVCEPYLVRSGLLARTPRGRVATVHGWRHLGRTPPRASAAGAVQAALFDEDETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYR8</accession>
    <name>D3PYR8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019072.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3845"/>
    <dbReference type="EnsemblBacteria" id="ADD43501">
        <property type="protein sequence ID" value="ADD43501"/>
        <property type="gene ID" value="Snas_3845"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3845"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089258_0_1_11"/>
    <dbReference type="OMA" id="HDRPLHY"/>
    <dbReference type="OrthoDB" id="1629615at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="7"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="174" mass="19767" checksum="E1834E9AC3E764C3" modified="2010-04-20" version="1">MSVGHTLLGLLEQQPRHGYDLKRAYDERFGGDHPLHYGQVYSTLQRLLKNGLVEVDGVEAGGGPERKRYAVTDAGITDVATWLRQPEKPEPYLQNTLYTKVVMAILTGRDAAELLDVQRSEHLRLMRELTKRKTQGDFADQLICDHALFHLEADLRWLELTSDRLDKLTAEVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYX3</accession>
    <name>D3PYX3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43556">
        <property type="protein sequence ID" value="ADD43556"/>
        <property type="gene ID" value="Snas_3901"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3901"/>
    <dbReference type="HOGENOM" id="CLU_1194306_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="232" mass="24568" checksum="65EF1FE82F8853DC" modified="2010-04-20" version="1">MAGIARGSASCQLRNAIDALAAALAGLDRMAEAETTVHEHVAAYLASIGASQSAPAQESEKTGLKKPTGPADLKAVGERLGLNAYAAMMGSDYWAPLDDDAAVAALFVSLKSTVGQDGHRCVATIGPETDDGIQPHLEVATDGANTYLRSDGNIATEPGRTVPEFHAVHHPDGEPTIHHTHTFETRTGLEDIPVNHTRVSPNWAVDTVKRYIDTGERPDRVKWIDPSAGTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYY7</accession>
    <name>D3PYY7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Abortive infection protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5786"/>
    <dbReference type="EnsemblBacteria" id="ADD45416">
        <property type="protein sequence ID" value="ADD45416"/>
        <property type="gene ID" value="Snas_5786"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5786"/>
    <dbReference type="eggNOG" id="COG1266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1034092_0_0_11"/>
    <dbReference type="OMA" id="GARQENS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="269" mass="28610" checksum="2FB55580FFF1B3B1" modified="2010-04-20" version="1">METIAAVENQPRLRPGWRIPLTVVGMFAFVGAGIATSALLSLLPVPGPAVRIATLTAMAAAAIGVVYCLRRFVDRRPWRDLGLTWRPADVLPLLLGGALAALVVLTAHLGAIALGLSDWRPTFEDGLPLIPGLLLGYLMILLGQAFPEELLWRGYLLTSLSADWRRWAAVGATALGFGAMHVISNPGTDASLGWRLLYAVMACGLGFAAASCRLRGGTIWLAVGFHAGHNLTGKVLNTGAYDWSLLVSFAVFLGFGLVMLRTAPRRSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZH8</accession>
    <name>D3PZH8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017223.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1956"/>
    <dbReference type="EnsemblBacteria" id="ADD41652">
        <property type="protein sequence ID" value="ADD41652"/>
        <property type="gene ID" value="Snas_1956"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1956"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_13_1_11"/>
    <dbReference type="OMA" id="FEADWYV"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="138" mass="15605" checksum="49E6AF02636A313B" modified="2010-04-20" version="1">MRLNSFYPVIGTERIAESTAFYTQHFGFEITFQADWYVSLNRPGDRSYELALLDPSHETVPAAYRRPVAGLLLNFEVDDVDAEYDRLVTTAGLKPELDIRSEDFGQRHFIVADPNGVLIDVITNIEPVGEYAEQYVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZK9</accession>
    <name>D3PZK9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cysteine dioxygenase type I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1987</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cysteine dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017254.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1987"/>
    <dbReference type="EnsemblBacteria" id="ADD41683">
        <property type="protein sequence ID" value="ADD41683"/>
        <property type="gene ID" value="Snas_1987"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1987"/>
    <dbReference type="eggNOG" id="COG5553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118472_0_0_11"/>
    <dbReference type="OMA" id="DHRVWGL"/>
    <dbReference type="OrthoDB" id="1571420at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010300">
        <property type="entry name" value="CDO_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918">
        <property type="entry name" value="PTHR12918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05995">
        <property type="entry name" value="CDO_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0883">Thioether bond</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="cross-link" description="3'-(S-cysteinyl)-tyrosine (Cys-Tyr)" evidence="2">
        <location>
            <begin position="101"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="181" mass="19625" checksum="033268847A1E7C0E" modified="2010-04-20" version="1">MSTTTAFRAPEVTARLAHLVGRVREAVSRGLPPQQTAELVADRLAPHMGAPGLLTDEQCVGDPSCYRQHLLHAEHDGSFSLLALVWLPGHQTPVHDHVSWCVTGVHRGQESERRYRLVPGSPARLVATADVVNPQGTVCGFAPPGDIHKVRNATAHKAISLHVYGADISRIGSSVRRTYQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q040</accession>
    <name>D3Q040_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5942</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021140.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5942"/>
    <dbReference type="EnsemblBacteria" id="ADD45569">
        <property type="protein sequence ID" value="ADD45569"/>
        <property type="gene ID" value="Snas_5942"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5942"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="ATMLKPN"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="227" mass="24179" checksum="C29416BEF2FA637C" modified="2010-04-20" version="1">MIRLTKVTKTYPGDVTALDEVSLDVDPGELVAIAGPSGSGKSTMLNVIGTLDRCSSGDVRIAGHDVSGLSDAQLSALRARHIGFVFQHFHLASGVMALDNVADGLLYSGHSLSRRRELAETALRRVGLGHRLDHEPHELSGGEKQRVAIARAVAGNPPLLLADEPTGALDSVSGTQVMELLRELNDSGTTVVIITHDREIAASLPRQVRMRDGRIETPSLSGRVMTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q081</accession>
    <name>D3Q081_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5984</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021181.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45610">
        <property type="protein sequence ID" value="ADD45610"/>
        <property type="gene ID" value="Snas_5984"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5984"/>
    <dbReference type="eggNOG" id="ENOG503334W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183126_0_0_11"/>
    <dbReference type="OMA" id="WHELTGH"/>
    <dbReference type="OrthoDB" id="1831235at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="96" mass="10682" checksum="F7C72BFA5B7F303A" modified="2010-04-20" version="1">MLGAMAESTLDELSTEQLRERAFARARQRHDLGFFWDVVRHLPHAPEAEEVDGSLGSVGAAIDSVVALWHELTGHDTDYGSSEPLLRAKFIDYLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0F2</accession>
    <name>D3Q0F2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-quinone oxidoreductase subunit D</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NADH dehydrogenase I subunit D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nuoD</name>
        <name evidence="9" type="ordered locus">Snas_0095</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015387.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0095"/>
    <dbReference type="EnsemblBacteria" id="ADD39816">
        <property type="protein sequence ID" value="ADD39816"/>
        <property type="gene ID" value="Snas_0095"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0095"/>
    <dbReference type="eggNOG" id="COG0649">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015134_1_2_11"/>
    <dbReference type="OMA" id="GGRMHYM"/>
    <dbReference type="OrthoDB" id="473681at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014029">
        <property type="entry name" value="NADH_UbQ_OxRdtase_49kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="PTHR11993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00535">
        <property type="entry name" value="COMPLEX1_49K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5" id="KW-0874">Quinone</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-1278">Translocase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 5 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Complex1_49kDa" evidence="8">
        <location>
            <begin position="132"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Complex1_49kDa" evidence="8">
        <location>
            <begin position="304"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD39816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="378" mass="41486" checksum="B36D9DDA73C8D08A" modified="2010-04-20" version="1">MTEMTVGVGSGVGEFADMVLNIGPQHPSTHGVLRLKLTLDGERVTGCEPVVGYMHRGAEKLFEVRDYRQILMLANRHDWLSAFCSELGVALAVERLMGIEVPERAVWLRTALAELNRVLNHLMFLGSYPLEIGAITPMFYAFRERETLQAVFEEASGGRMHYMFNRIGGLKEEVPSGWTSRARQAIGEVRRGMSDVDDIIRTNEIFAARTKGVGVLSAETAAAYGVSGPVARASGLDFDLRRDEPYLAYGELDVPVVTRTAGDCHARFGCLLDQVYVSLDLAEKCLNRVDAIGGPVNVRLPKVVKAPEGATYAWTENPLGVNGYYLVSRGEKTPWRLKLRTASYANVQALSTLLVGCLVPDLVAILGSMFFVVGDIDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0L1</accession>
    <name>D3Q0L1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">AzlC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_2053</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AzlC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2053"/>
    <dbReference type="EnsemblBacteria" id="ADD41747">
        <property type="protein sequence ID" value="ADD41747"/>
        <property type="gene ID" value="Snas_2053"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2053"/>
    <dbReference type="eggNOG" id="COG1296">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065777_0_1_11"/>
    <dbReference type="OMA" id="DFAFPAV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011606">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34979">
        <property type="entry name" value="PTHR34979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03591">
        <property type="entry name" value="AzlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD41747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="225" mass="22682" checksum="AE6B3E70D9F0B6BA" modified="2010-04-20" version="1">MERTNYREQLRDVAPLAGSAAILGASFGAIAVAAGLPLWMACAMSVLVFAGGSQFLVVGVIAAGGGAIAAVAGGLILNARHLPFGLAVGDALDGGWLKRLVGSHLLVDESTAFYLAAPDPHRARAAYWASGVSLFVTWNLGTLAGAFAGQAISDPKMFGLDAAFPAALLALVLPRLKEAPVLRASVLGAVIAVATTPFLPGGVPVLLALLGLVAALPVPKREAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q196</accession>
    <name>D3Q196_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021247.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6052"/>
    <dbReference type="EnsemblBacteria" id="ADD45676">
        <property type="protein sequence ID" value="ADD45676"/>
        <property type="gene ID" value="Snas_6052"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6052"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_905895_0_0_11"/>
    <dbReference type="OMA" id="RLEWRPG"/>
    <dbReference type="OrthoDB" id="1581296at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="178"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="315" mass="35460" checksum="0358E98CB2FABE9A" modified="2010-04-20" version="1">MPRDDLTIRPLADAGELDLFQRLDYVLDDELADDLATNRRRPRWLWIATRDDRVLARAGWWGGPDDEVPASFDFFDVDDSLPVDEAVAVGVELVATALRHVVPSGATPPEYGRFIPPDWREDPAARQAVETRFAVLERLGARQLVERLRLEWRVGTPLPKRSTRLRFRAVADREELITLMTPVQQGTLDAHSQSDLASLSPEAAAAKHFDEEFAHFESPRDWWRVATLDDGEPVGFVIAARNTYNPIIAYLGVLPQHRGHGYVDDLLAEGTHILAAQDVPRIRAATDLANVPTARAFERAGYVNFARAVNFTWEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1H6</accession>
    <name>D3Q1H6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylhydroperoxidase like protein, AhpD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015395.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0103"/>
    <dbReference type="EnsemblBacteria" id="ADD39824">
        <property type="protein sequence ID" value="ADD39824"/>
        <property type="gene ID" value="Snas_0103"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0103"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_6_1_11"/>
    <dbReference type="OMA" id="SETHAPD"/>
    <dbReference type="OrthoDB" id="1893149at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="18"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="157" mass="16864" checksum="3D65173047222584" modified="2010-04-20" version="1">MNARLNAFENPVLGKVFKHLIAANKSLADTGLPHTTQELVKIRASQINSCGFCTDMHTKDALAAGETQQRLNLVAAWREATVFTDAERAALELAEEGTRIADAAGGVSEDVWANAAKHYDENQLGALVSLIALINAFNRGNVIIQQPAGDYQPGMFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1I9</accession>
    <name>D3Q1I9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH_hydro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0116"/>
    <dbReference type="EnsemblBacteria" id="ADD39837">
        <property type="protein sequence ID" value="ADD39837"/>
        <property type="gene ID" value="Snas_0116"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0116"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038449_4_1_11"/>
    <dbReference type="OMA" id="CLRSTAN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01823">
        <property type="entry name" value="SEST_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037460">
        <property type="entry name" value="SEST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981">
        <property type="entry name" value="PTHR37981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049450" description="SGNH_hydro domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="36"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="287" mass="30110" checksum="233EA96F9362B538" modified="2010-04-20" version="1">MRRRTPLTAAACLAVLAVSAPAPAFAHSAPIDEYVALGDSSVAGPLIPDWDTGEPGCLRSTNNWAVEVADELGVANLTDVSCSAATAEHMANPQSLPLGGSAPPQFDALSDTTDLVTTTIGGNDVGLVGEALKCVNLLPEPAGQSCKDRLTSGGVDQLAAKIDAFEPAFGEMLDGIREHAPNARVVVVGYGTYIQPGGCYPETPVWSRDADYLQDTIGRLDDMMARQSAEHGVEFIDIREATKGRNLCAPTGTRWYESLIPTSPATPLHPNRIGMTGIGEAVAAELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1T8</accession>
    <name>D3Q1T8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lanthionine synthetase C family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015507.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0217"/>
    <dbReference type="EnsemblBacteria" id="ADD39936">
        <property type="protein sequence ID" value="ADD39936"/>
        <property type="gene ID" value="Snas_0217"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0217"/>
    <dbReference type="eggNOG" id="COG4403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049722_0_0_11"/>
    <dbReference type="OMA" id="LADRCWH"/>
    <dbReference type="OrthoDB" id="393144at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="411" mass="44394" checksum="595E777C0AF08FDE" modified="2010-04-20" version="1">MNETRTPEELGRGGLDWLLTTARQTDDGLAWPVQPSADNVDHMLYWGTPGIVVAMLEGQRHFGDDRYGDAAARGATAMAAAITDCEGSSLYTGTTGLAVTLHAVGEQLGDDEYTAAATRALKLTRSRFDGTRWGELFELLLGNAGIALGAKYCGDLDLAVDALEPYLRTAEPTEHGVQWEHRPGAESRMHHFSHGTLGIAHALAEIGAAANRPDFTELALAGVADVVARDEAGPDGFLVPHSDPWDDTRQASRYNYGWCHGPAGDAHVFRLLRDLTGDPQWTALADRCWHTITHSGLPRRTRPGFWDNNGRCCGTASVLALANDRLVERDDDPAFAQVLVDDLAQRATVTDTGVCWSNVEHSADPSELEPQTGWAMGNAGIVRELLRYSRIRSGGQSGYAVGLPDQPAART</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1U7</accession>
    <name>D3Q1U7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SMP-30/Gluconolaconase/LRE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015516.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0226"/>
    <dbReference type="EnsemblBacteria" id="ADD39945">
        <property type="protein sequence ID" value="ADD39945"/>
        <property type="gene ID" value="Snas_0226"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0226"/>
    <dbReference type="eggNOG" id="COG3386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036110_4_0_11"/>
    <dbReference type="OMA" id="VTQFRAN"/>
    <dbReference type="OrthoDB" id="852341at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005511">
        <property type="entry name" value="SMP-30"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01790">
        <property type="entry name" value="SMP30FAMILY"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGL" evidence="1">
        <location>
            <begin position="13"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="294" mass="31732" checksum="113AC7CEDF8AB8E4" modified="2010-04-20" version="1">MDEPKVVLSDLVVGESPRWHEGRLWFCNWGAHEIIAVDPDGNAEVVLRDAEVDPHSIDWLPDGRMLIVPKNTERGRLLRREPNGDIVSHADLSGLPSGFNEIVVDGRGNVYVNGADFDFLSFISTLDHTDQRPLHLRPGFVPGFIALITPDGRSRIVAEDIAFPNGMLVTPDNATLIISESFAGRLSAFDVAADGGLSGRRVWAEGLGPDGICRDADGAVWTSSGETDCVRVAEGGEILDRVDFDRSPFACMLGGPERRTLYVVAATWNPENPFGGRTGQLLAVPAPAAGVGWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q242</accession>
    <name>D3Q242_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2218</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PhoU family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017480.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2218"/>
    <dbReference type="EnsemblBacteria" id="ADD41909">
        <property type="protein sequence ID" value="ADD41909"/>
        <property type="gene ID" value="Snas_2218"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2218"/>
    <dbReference type="eggNOG" id="COG0704">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078518_1_0_11"/>
    <dbReference type="OMA" id="ENDHQIN"/>
    <dbReference type="OrthoDB" id="1648549at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="4">
        <location>
            <begin position="16"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="4">
        <location>
            <begin position="122"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="216" mass="24131" checksum="F216D3D55092BC05" modified="2010-04-20" version="1">MRDTFHADLDTLNDQLIEMSRSVAEAMRGASRVLVESDTARASEVIAGDTDINELQYTVDDRVTEIMTQRQAVATDLRFILSSIRIATDLERMGDMARHVAKLAQRLDPDGALTQTRPIFEAMATAAARIADKTTRVLETRDRLDATQLDLDDDEMDALYSRLLGQLSSQWTHGAEAAVDVAMIGRSYERYGDHAVRIGHQVVYLVTGEIHLDRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q269</accession>
    <name>D3Q269_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_2246</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2246"/>
    <dbReference type="EnsemblBacteria" id="ADD41936">
        <property type="protein sequence ID" value="ADD41936"/>
        <property type="gene ID" value="Snas_2246"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2246"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012341_2_0_11"/>
    <dbReference type="OMA" id="IRAMMRR"/>
    <dbReference type="OrthoDB" id="856767at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038766">
        <property type="entry name" value="Membrane_comp_ABC_pdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30287">
        <property type="entry name" value="PTHR30287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049655" evidence="7">
        <location>
            <begin position="37"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="483"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="711"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="764"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="798"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="25"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="291"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="740"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD41936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="838" mass="85309" checksum="E9F2EADF00F22683" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q338</accession>
    <name>D3Q338_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015579.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0290"/>
    <dbReference type="EnsemblBacteria" id="ADD40008">
        <property type="protein sequence ID" value="ADD40008"/>
        <property type="gene ID" value="Snas_0290"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0290"/>
    <dbReference type="eggNOG" id="ENOG5032KA1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099329_0_0_11"/>
    <dbReference type="OMA" id="GWEITVY"/>
    <dbReference type="OrthoDB" id="1531419at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048615" evidence="1">
        <location>
            <begin position="23"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="22524" checksum="603ADD3261FC3186" modified="2010-04-20" version="1">MTARAVLAVAALALLGGCGDKAEPKSTAESGWEITVYYTAVESFHDGETVEVTGCSELDCENGDDPLGEYPRDFVKAVKDEGTGRITSGDHEGEYLNWSHGVGYWLDEEARNSHGDALRPYVSAATDADVLPKGTRVEIVACGDADVPDKVCDKLMKPTWTIDDEFTPGLGGEKHLDVYLGEEDREDFTESQWYTTLENAELRIHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q379</accession>
    <name>D3Q379_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015620.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0331"/>
    <dbReference type="EnsemblBacteria" id="ADD40049">
        <property type="protein sequence ID" value="ADD40049"/>
        <property type="gene ID" value="Snas_0331"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0331"/>
    <dbReference type="HOGENOM" id="CLU_2525936_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="84" mass="9164" checksum="14F611C19898EBC4" modified="2010-04-20" version="1">MPFSQSHNEFDRLAAAAHALHDAVHEFMAEFHGAGAEITDDDRSRKVFDNLAAVDTDAVLVLDRLTRTGHHQQASELAVPSAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3H6</accession>
    <name>D3Q3H6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NMT1/THI5 like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017588.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2330"/>
    <dbReference type="EnsemblBacteria" id="ADD42017">
        <property type="protein sequence ID" value="ADD42017"/>
        <property type="gene ID" value="Snas_2330"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2330"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028871_5_1_11"/>
    <dbReference type="OMA" id="TSLMIAQ"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049510" evidence="1">
        <location>
            <begin position="26"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="2">
        <location>
            <begin position="41"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="314" mass="32988" checksum="CAA3B91E31088F7F" modified="2010-04-20" version="1">MRNQLAPLAILLALGTTACSPSESADDGGENVTVGVIPIVDVAPIYLGEKQGFFADRDIDLKLEAGQGGAAIVPGVSSGDFQFGFSNLTSLMSAQTEGLKVQAVAPGVASTGKAGDDFGAVVVPKGSSIKSAKDLPGHTVAVNTLNNIGDTTIRESIRVDGGKPDDVEFTEFGFPDMPAQLDDGNVDAAWVVEPFLSIAKESGARPIAWNYVDIADDLTVAAYFTTTEFVDKDPDLVKRFTAAMTESLEYAAKHPDEVRDILSEYADIDAAIAEKITLPAWPSAINEKSTARLAELGVSDGVLKSEPDLKSLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3X6</accession>
    <name>D3Q3X6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrolase transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019614.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4397"/>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44043">
        <property type="protein sequence ID" value="ADD44043"/>
        <property type="gene ID" value="Snas_4397"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4397"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019399_0_1_11"/>
    <dbReference type="OMA" id="NLVNIMT"/>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048851" evidence="1">
        <location>
            <begin position="29"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="324" mass="34198" checksum="1F916D3B0EDBD0FC" modified="2010-04-20" version="1">MPPKRLALAVPALILGLVVALTASPAQARQPAPEPDTRAVAIKTAPYIDITRPSPTLPEVAAATGQKYFTLAFVLGSHAGCAPAWGGTIDLDEPSIINQINQLRGMGGDVIIASGGALGPYLEHSCGSATALYDAYVKVLNATGSNHLDVDVEASIPHSMVNQALKRLVDERGTTISYTLRVQGQDYGLDPYSVQILQDAKAKGLRPIVNPMLMNFGYSGDWGQAMISAAQAVIGQMNQIWTGGGNAVYLGITPMIGRNDTGMTTTQSHARALLSWARSNSIAFIGFWSIGRDNGRCSGGGVRPDCSGISQSTYEFTNIFKGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q425</accession>
    <name>D3Q425_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_6290</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021481.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6290"/>
    <dbReference type="EnsemblBacteria" id="ADD45910">
        <property type="protein sequence ID" value="ADD45910"/>
        <property type="gene ID" value="Snas_6290"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6290"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_11"/>
    <dbReference type="OMA" id="AFVQYIW"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="34"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="354"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="387"/>
            <end position="394"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD45910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="598" mass="64136" checksum="444FF31A9FCD02B3" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q446</accession>
    <name>D3Q446_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphatidylserine decarboxylase</fullName>
            <ecNumber evidence="5">4.1.1.65</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6313</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.1.65" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021502.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6313"/>
    <dbReference type="EnsemblBacteria" id="ADD45931">
        <property type="protein sequence ID" value="ADD45931"/>
        <property type="gene ID" value="Snas_6313"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6313"/>
    <dbReference type="eggNOG" id="COG0688">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_658706_0_0_11"/>
    <dbReference type="OMA" id="EHNVAAY"/>
    <dbReference type="OrthoDB" id="891720at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033175">
        <property type="entry name" value="PSD-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35809">
        <property type="entry name" value="PTHR35809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0865">Zymogen</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="404" mass="42620" checksum="AF3E22D691949280" modified="2010-04-20" version="1">MSNSTSLGRRAARVLADEFIRHPGPKTGLVIGARPHDPVLAAAIDALLPDDRLTVVATDAERGGMEAYLAEQGSWVTERVTLVPSLSEAKAADVVMLAAPVTAELDSHAEYLRELTAPGGVLCLSAPLTAAAAEEIADLVGEHGIGSDLVLRNRPPVRIHRLRFSEADAALAERAAPATRSSSVPLTSRMHIDSNGLAAGAILLGVAGLTKKIRPNSKLWLLPAVAAAPAAAFFRDPQRNIDPDPKTVVASGDGKVLSVERVVDERFGAVSGAAGTEWLRIAVFLSILDVHVNRAPVAGRVVDIFREAGSNAPAMKPAAEHNVACYTVVDTPRGRVVTAQRTGMIARRIVNRTQVGAVLAKGERYGLIRFGSRTDVYLPADAADALVSPNDKVIGGETAIARWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q469</accession>
    <name>D3Q469_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021525.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6337"/>
    <dbReference type="EnsemblBacteria" id="ADD45954">
        <property type="protein sequence ID" value="ADD45954"/>
        <property type="gene ID" value="Snas_6337"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6337"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_10_0_11"/>
    <dbReference type="OMA" id="VGFEGMR"/>
    <dbReference type="OrthoDB" id="1900922at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="136" mass="14945" checksum="AA20E861E72F71CD" modified="2010-04-20" version="1">MNIELSTTFIAVDDHDKAIAFYRDVLGLEVRNDVGFENMRWVTVGAPTQPDVAIVLEPPIGDPNASEADKKAAAELLAKGLLRGVIFETDDVDATFERIRAAGGDVLQEPVDQPFGVRDCAFRDPAGNMLRFNQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4D3</accession>
    <name>D3Q4D3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015664.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0376"/>
    <dbReference type="EnsemblBacteria" id="ADD40093">
        <property type="protein sequence ID" value="ADD40093"/>
        <property type="gene ID" value="Snas_0376"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0376"/>
    <dbReference type="HOGENOM" id="CLU_2636316_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="77" mass="8942" checksum="079733BB68DF2494" modified="2010-04-20" version="1">MSFTDSETLARNANYTMKCHSKVDTEGYCTGCRNYHGKLERPGPEGCYFYRLAFEVYRKHALSHSIQGDDNVYIRHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4R3</accession>
    <name>D3Q4R3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyridoxal 5'-phosphate synthase subunit PdxS</fullName>
            <shortName evidence="3">PLP synthase subunit PdxS</shortName>
            <ecNumber evidence="3">4.3.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Pdx1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pdxS</name>
        <name evidence="6" type="ordered locus">Snas_2410</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">In the presence of PdxT, forms a dodecamer of heterodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the PdxS/SNZ family.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017664.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2410"/>
    <dbReference type="EnsemblBacteria" id="ADD42093">
        <property type="protein sequence ID" value="ADD42093"/>
        <property type="gene ID" value="Snas_2410"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2410"/>
    <dbReference type="eggNOG" id="COG0214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055352_1_0_11"/>
    <dbReference type="OMA" id="RYANRGW"/>
    <dbReference type="OrthoDB" id="784095at2"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04727">
        <property type="entry name" value="pdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01824">
        <property type="entry name" value="PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001852">
        <property type="entry name" value="PdxS/SNZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033755">
        <property type="entry name" value="PdxS/SNZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829">
        <property type="entry name" value="PTHR31829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01680">
        <property type="entry name" value="SOR_SNZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029271">
        <property type="entry name" value="Pdx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00343">
        <property type="entry name" value="TIGR00343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01235">
        <property type="entry name" value="PDXS_SNZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51129">
        <property type="entry name" value="PDXS_SNZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <feature type="domain" description="SOR_SNZ" evidence="5">
        <location>
            <begin position="15"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribose 5-phosphate binding" evidence="3">
        <location>
            <begin position="243"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with D-ribose 5-phosphate" evidence="3">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="302" mass="31712" checksum="47CCA37429F313DB" modified="2010-04-20" version="1">MSSEQTSQAKATGTARVKRGMADMLKGGVIMDVVTPDQAKIAEDAGAVAVMALERVPADIRVQGGVARMSDPDMIDGIISAVSIPVMAKARIGHFAEAQVLQSLGVDYIDESEVLTPADEANHIDKWPYTVPFVCGATNLGEALRRIGEGAAMIRSKGEAGTGNVVEATRHMRQIRADIKRLTTLDSTELYAAAKELRAPVELVAEVAEAGKLPVVLFTAGGIATPADAAMMMQLGAEGVFVGSGIFKSGDPAKRAEAIVKATAFHDDPSVIAKVSRGLGEAMVGLNVDTLPAEQQYAKRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Z9</accession>
    <name>D3Q4Z9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">Enoyl-[acyl-carrier-protein] reductase [NADH]</fullName>
            <ecNumber evidence="9">1.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Snas_2497</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 2,3-saturated acyl-CoA + NAD(+) = a (2E)-enoyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:18177"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="2">
            <dbReference type="Rhea" id="RHEA:18179"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10240"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.9"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="1">
            <dbReference type="Rhea" id="RHEA:10242"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; mycolic acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017750.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2497"/>
    <dbReference type="EnsemblBacteria" id="ADD42179">
        <property type="protein sequence ID" value="ADD42179"/>
        <property type="gene ID" value="Snas_2497"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2497"/>
    <dbReference type="eggNOG" id="COG0623">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_10_1_11"/>
    <dbReference type="OMA" id="GILDMIH"/>
    <dbReference type="OrthoDB" id="762291at2"/>
    <dbReference type="UniPathway" id="UPA00915"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016631">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050343">
        <property type="term" value="F:trans-2-enoyl-CoA reductase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05372">
        <property type="entry name" value="ENR_SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="PTHR43159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000094">
        <property type="entry name" value="Enoyl-ACP_rdct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 9 11" id="KW-0520">NAD</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="64"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="190"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD42179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="27514" checksum="2D129FCA49376A18" modified="2010-04-20" version="1">MTGLLDGKRLLITGLITDQSLAFGVAKLAQEQGAEVVLTGFGRMSLVNRIAARLPKPAPVVELDVTDQEQLDSLAERVREHVPALDGVLHSIANAPQSCLGGGFMTAPWEDVAKALHVSTFSFKSLAVACLPLMESGGAIVGMDFDASQAWPVYDWMGVSKAGLESVTRYMARDLGPKGIRVNLVAAGPVRTMAAKSIPGFEQFETAWAERAPLGWSLTDSTPVAKAVTMLLSDWFPATTGEIVHVDGGFHAVGVKAAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q533</accession>
    <name>D3Q533_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">DNA repair protein RecN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombination protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_4437</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">May be involved in recombinational repair of damaged DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the RecN family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019653.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4437"/>
    <dbReference type="EnsemblBacteria" id="ADD44082">
        <property type="protein sequence ID" value="ADD44082"/>
        <property type="gene ID" value="Snas_4437"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4437"/>
    <dbReference type="eggNOG" id="COG0497">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018297_3_0_11"/>
    <dbReference type="OMA" id="QVICVTH"/>
    <dbReference type="OrthoDB" id="1074831at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004604">
        <property type="entry name" value="DNA_recomb/repair_RecN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11059">
        <property type="entry name" value="PTHR11059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003128">
        <property type="entry name" value="RecN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00634">
        <property type="entry name" value="recN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC_N" evidence="9">
        <location>
            <begin position="2"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="345"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR003128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD44082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="583" mass="60804" checksum="0EAB4DD3B2692ECD" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q550</accession>
    <name>D3Q550_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019670.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4454"/>
    <dbReference type="EnsemblBacteria" id="ADD44099">
        <property type="protein sequence ID" value="ADD44099"/>
        <property type="gene ID" value="Snas_4454"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4454"/>
    <dbReference type="HOGENOM" id="CLU_2720405_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="72" mass="8024" checksum="83EACA3A7D04FCC2" modified="2010-04-20" version="1">MQWWLILLIGLGFGVLVVAVAGLAVRSRMTDLQMALTTLDEHKLAGERLGQRAEKLQADIERLQARIPQQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5D1</accession>
    <name>D3Q5D1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LytR_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4535"/>
    <dbReference type="EnsemblBacteria" id="ADD44180">
        <property type="protein sequence ID" value="ADD44180"/>
        <property type="gene ID" value="Snas_4535"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4535"/>
    <dbReference type="eggNOG" id="ENOG5032WRF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126943_0_0_11"/>
    <dbReference type="OMA" id="RAYFLNN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027381">
        <property type="entry name" value="LytR/CpsA/Psr_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13399">
        <property type="entry name" value="LytR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048674" description="LytR_C domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_C" evidence="2">
        <location>
            <begin position="56"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="172" mass="18425" checksum="AB6F22BCE0973D05" modified="2010-04-20" version="1">MRITQVRALIVVGVLILIAVSTSWYAIANDSQTAAGRENCEPGDIPVDVTLPEPHQVSVKVLNATNTSDLAGSAAGSLKEYGFKIEDTGESKKDEGKSSVEIHYGPKALGGGHLLRSYFADDTAVFDLKNENDFVEIILFDGFQQVNTESDARNEVGIIGRPEAPEGTCAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5D7</accession>
    <name>D3Q5D7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021568.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6381"/>
    <dbReference type="EnsemblBacteria" id="ADD45997">
        <property type="protein sequence ID" value="ADD45997"/>
        <property type="gene ID" value="Snas_6381"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6381"/>
    <dbReference type="HOGENOM" id="CLU_1314754_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="209" mass="21110" checksum="11EE66B09FEB839F" modified="2010-04-20" version="1">MPTTSQSASDLPATRPISTVASVAAAVVGVAAFFGAGWWLFLSFGAAFFADDTSSSVFLAHAAVLFIALGAAAIGIARGRYFAWLAAVSGCAATVGAGLTQLVEDLRVEPPVDATDAFLEGAMIIPAAVAAAAVILLWLRGVRDWCSSRSGVVWLIPVLGLVIAGGVGVPLVFGSSFKFVVGVGAAAAVVAGLISFAATRRQPSDSKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5E6</accession>
    <name>D3Q5E6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021577.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6390"/>
    <dbReference type="EnsemblBacteria" id="ADD46006">
        <property type="protein sequence ID" value="ADD46006"/>
        <property type="gene ID" value="Snas_6390"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6390"/>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038929_0_0_11"/>
    <dbReference type="OrthoDB" id="1757114at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD46006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="422" mass="44445" checksum="6575F1A73FEB02E4" modified="2010-04-20" version="1">MTIGRRLSWGLADQAVIAAANAGNGLLATVFLPPAEAGIVLVCLATVYVAMGLNRAFIGDVLLAQASRFEGTSRRRMHTDAIATACCSGTAVAVVLALLWLLWPGRLLDPLIYLVPFIPALFAHDTARYSYQSQLRQRSAFVIDIAWVLVQGGLVGIGAALGALSGPWLLVAWGLGACIGAIVYLLRGGIVPWRGRPVRWLAHTRKLSVWFTGSAVIGQAQIQLIALLIPSLLGAAAFAGLRLAHLVILQPIQNLVLASMGLLVPRTSTLTEAGNIEGLRNQTKKVVVIALGLAVVLLAVVTLAAEPVLSWYQGGAYAEVAPLAWPVGIQAGIYLLQIPFTATVRGMRQGKLVFLQYALFTVTSLLGVGIGATTFGLTGAAWGLTVGSAVGLAVMIYLAMYAMRQLTTPPVRQSLVPAESSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5L3</accession>
    <name>D3Q5L3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chaperone protein ClpB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">clpB</name>
        <name evidence="13" type="ordered locus">Snas_6458</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homohexamer; The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021644.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6458"/>
    <dbReference type="EnsemblBacteria" id="ADD46073">
        <property type="protein sequence ID" value="ADD46073"/>
        <property type="gene ID" value="Snas_6458"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6458"/>
    <dbReference type="eggNOG" id="COG0542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005070_4_0_11"/>
    <dbReference type="OMA" id="SKMMQGE"/>
    <dbReference type="OrthoDB" id="44062at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017730">
        <property type="entry name" value="Chaperonin_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03346">
        <property type="entry name" value="chaperone_ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 11" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="12">
        <location>
            <begin position="3"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="414"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD46073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="864" mass="93954" checksum="991B08E0EF757873" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5S5</accession>
    <name>D3Q5S5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0509</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015795.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40224">
        <property type="protein sequence ID" value="ADD40224"/>
        <property type="gene ID" value="Snas_0509"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0509"/>
    <dbReference type="HOGENOM" id="CLU_2939555_0_0_11"/>
    <dbReference type="OrthoDB" id="1963656at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="60" mass="6675" checksum="20A827185B01F71F" modified="2010-04-20" version="1">MTETRRSRIKPVKDGYLPITELTSPVSAAGSPFGEDGEVFPLPVDQLNYEHSEPVPPREH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q611</accession>
    <name>D3Q611_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0596</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0596"/>
    <dbReference type="EnsemblBacteria" id="ADD40310">
        <property type="protein sequence ID" value="ADD40310"/>
        <property type="gene ID" value="Snas_0596"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0596"/>
    <dbReference type="HOGENOM" id="CLU_962810_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="263"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="289" mass="32091" checksum="221CFB85B2D7C0D7" modified="2010-04-20" version="1">MTTPSEIRQIAQQIYELAQEKRMIEWVRDHPDSTDTKEDLGLAEKYAYIEGEFERFTEPNLTPFDDISKQLEDAYDKIAGKDASYLSSDSSLKIAEWRGTAKTSFDDNYITPWETYREFHKELIRALKSAADSHRDLYSRMRGRAYSIGEATVEGLKGIDGWPPFLSEKEGKDILFKVAGLLSIAASASPMGAVAKAVAVIQIADASRTVTEAAGSIEAKFVNEILDQMKKKLDELEDDSQAEEKTISKGLKKNIDAIEKKLDDIVPPSPELADVNPDDPGGKLKPPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6A9</accession>
    <name>D3Q6A9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2605</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017855.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2605"/>
    <dbReference type="EnsemblBacteria" id="ADD42284">
        <property type="protein sequence ID" value="ADD42284"/>
        <property type="gene ID" value="Snas_2605"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2605"/>
    <dbReference type="HOGENOM" id="CLU_126433_5_0_11"/>
    <dbReference type="OrthoDB" id="2025483at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13564">
        <property type="entry name" value="DoxX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="119" mass="12178" checksum="AE1F8A06D707840F" modified="2010-04-20" version="1">MTIASTILSIALIAFFGSLGGAKLVLAPSVVEHVTALGFSMRACRIIGGLEIAACLGLIVGFFWEPVSLVASLGLFTLMIGALRAQLWAGIDIRTALPAVWLGAVALAATVITAVNLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6C5</accession>
    <name>D3Q6C5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2622</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017871.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2622"/>
    <dbReference type="EnsemblBacteria" id="ADD42300">
        <property type="protein sequence ID" value="ADD42300"/>
        <property type="gene ID" value="Snas_2622"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2622"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_1_0_11"/>
    <dbReference type="OMA" id="AKDYPLM"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="100"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="35863" checksum="BA4FDF30FC3D4481" modified="2010-04-20" version="1">MRFLLRRAGFYLLTAWAAITLNFFIPRMLPGDPVQSLLNRYQGQLTSEATRSLYVLFGLDEQTSLWQQYLEYWGNIFTGDFGLSFTFFPTPVSEIVAQSLPWTLGLVGVSTVISFALGTLAGVIAGWRRGSWADTLLPVTNFFSAIPYFWIGLIAIAVFAEAWQLFPASGGWDTALVPSFSGEFIGSLITHSVLPGLTIVISSVAGWILSMRNMMVTVSSEDFVTVAHAKGLKERTVMFGYAARNAVLPNVSGFALSLGFIVSGTLLTEMVFSYPGIGYILFKAVDAKDYPLMQGVFLIITMSVLVANMLADLIYAFLDPRTRREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6D9</accession>
    <name>D3Q6D9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017885.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2637"/>
    <dbReference type="EnsemblBacteria" id="ADD42314">
        <property type="protein sequence ID" value="ADD42314"/>
        <property type="gene ID" value="Snas_2637"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2637"/>
    <dbReference type="HOGENOM" id="CLU_833968_0_0_11"/>
    <dbReference type="OMA" id="IPRFNAY"/>
    <dbReference type="OrthoDB" id="2149530at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="333" mass="35627" checksum="71C377B9C4C01512" modified="2010-04-20" version="1">MIKPKRPRLRRLLYAVLAIVVAATGVLVAQVATADSSRVDVKPATYRSPAYNAPMLHVKVASLTVNVSAGQAAYVNSNLRFGNATTRILVDSQLECFNSKGTSVRKLLRAQNVYAAGSGSLSKVSLTTRFLLPSKTAASFRCDLSLWTRSLGDAGRVSLTSGFVELAGKYRGTTQAATTSRALVSAGKPAWTPSVKGSASVPGESGLWQAPSGTKSLSVFGDFQLTTCYGKDKPPCPETANDKKGSSVRTTLVATQFKKDGSVCKTSTVSDDTRIQQYVHHQPVYLHNAKVPVVTGSGCVPVFSIYAKHQLRAYHPYYIHGRSEDALISVIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6J5</accession>
    <name>D3Q6J5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4594</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019809.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4594"/>
    <dbReference type="EnsemblBacteria" id="ADD44238">
        <property type="protein sequence ID" value="ADD44238"/>
        <property type="gene ID" value="Snas_4594"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4594"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_9_2_11"/>
    <dbReference type="OMA" id="CETDARH"/>
    <dbReference type="OrthoDB" id="1992113at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="19"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="120"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="191" mass="20912" checksum="DB3F938180821E2B" modified="2010-04-20" version="1">MTSVTVSRIGTVWDAFEEFYREHVGSIQGFIARRVDDPHLAADLTAEVFLAAMNSAHRYRPGKGTSAGWLFGIARNVVANDRRRRARAAQIDRRISGRALVDAEDLAALDDRIDAEAQSRQLYAAMDRLSDAERAVLELVALDGLSVADAAAALRIRPTAARKRLHRARKNMRDHLAPSAPALVAASTEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6R9</accession>
    <name>D3Q6R9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate--CoA ligase [ADP-forming] subunit beta</fullName>
            <ecNumber evidence="6">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Succinyl-CoA synthetase subunit beta</fullName>
            <shortName evidence="6">SCS-beta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sucC</name>
        <name evidence="9" type="ordered locus">Snas_0604</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015889.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0604"/>
    <dbReference type="EnsemblBacteria" id="ADD40318">
        <property type="protein sequence ID" value="ADD40318"/>
        <property type="gene ID" value="Snas_0604"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0604"/>
    <dbReference type="eggNOG" id="COG0045">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037430_0_2_11"/>
    <dbReference type="OMA" id="ITACDEV"/>
    <dbReference type="OrthoDB" id="316012at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_synthase_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="PTHR11815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="9"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding; shared with subunit alpha" evidence="6">
        <location>
            <begin position="318"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="52"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="392" mass="41245" checksum="75809E7B4A26F53F" modified="2010-04-20" version="1">MDLYEYQGRALFARHGVPVLDGGVAETVEEAVELAGKLDGRVVVKAQVKVGGRGKAGGVKLADNVDEAREHATNILGMDIKGHTVHKVMLTVTADIDTEFYFSFLLDRANRTFLCIASTEGGVEIEQVAAETPDKVLKLPINALTGVDATVAGEIADKAGFPADLRPQLVDMFVKLWETFVSEDATLVEVNPLVRTPEGRALALDAKVTLDENAAFRHLDHAELEDKAAVDPLEQRAKEADLNYVKLDGEVGIIGNGAGLVMSTLDVVAYAGEKHDNVKPANFLDIGGGASAAVMASGLEVVLSDPAVKSVFVNVFGGITACDEVANGIVGALTMLAERGETVDKPLVVRLDGNNAELGRSILDGANHPLVTRVDTMDGAADKAAELAAQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6V2</accession>
    <name>D3Q6V2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015922.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0638"/>
    <dbReference type="EnsemblBacteria" id="ADD40351">
        <property type="protein sequence ID" value="ADD40351"/>
        <property type="gene ID" value="Snas_0638"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0638"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086503_7_0_11"/>
    <dbReference type="OMA" id="WYFHIAD"/>
    <dbReference type="OrthoDB" id="1389691at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004343">
        <property type="term" value="F:glucosamine 6-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="PTHR13355"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="139" mass="14948" checksum="94613764C346F81F" modified="2010-04-20" version="1">MEDTYELREGVPSVADFRRLRTDAGLSDRSPEAVTLALPNTWYGVVIHHEGTPIGMGRIIGDGGTAFQIVDMCVNPAHQGKGLGKRIMAALTAELDRRAPATAYISLIADGPARHLYQQFGFIETTGYGSIGMSRVIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q706</accession>
    <name>D3Q706_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0692</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015976.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0692"/>
    <dbReference type="EnsemblBacteria" id="ADD40405">
        <property type="protein sequence ID" value="ADD40405"/>
        <property type="gene ID" value="Snas_0692"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0692"/>
    <dbReference type="HOGENOM" id="CLU_2195322_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="108" mass="11362" checksum="D15F088ADA49A6ED" modified="2010-04-20" version="1">MALEADYAALKDGSTKARTGGENIASAAQQMFAGLGEQQNALIGQAGSAFQRVQTVMQEQLVIIDRNLDQVAEGIDQSSLTFDSQDVDGSAEIDKAVDGTVDDLLKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7C5</accession>
    <name>D3Q7C5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uroporphyrinogen III synthase HEM4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017967.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2720"/>
    <dbReference type="EnsemblBacteria" id="ADD42396">
        <property type="protein sequence ID" value="ADD42396"/>
        <property type="gene ID" value="Snas_2720"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2720"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1587">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011276_9_1_11"/>
    <dbReference type="OMA" id="DAVCFTT"/>
    <dbReference type="OrthoDB" id="1185397at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006780">
        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40082">
        <property type="entry name" value="PTHR40082"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="274"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="274"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="368" mass="39194" checksum="86E8D79CC8161B99" modified="2010-04-20" version="1">MTGPLTGYTVAVTAQRRGEELAALLGRRGAKTVLAPVLRMVSLPDDQALRAATVELINDPPDVTIATTGIGFRGWLAAAEGWGLGEALHAALGSGRVWCRGPKALGAVRAAGLREEWSAPSECGWEVSERLRGEPLSGQRVAVQLHGDPSDDFTDTIRSGGGHAVPIPVYRWMLPTDITPVRRLVDQVCLRRIDAVTFTSAPAVNALLRIAGDQRTELLAALRAPADDGGVMAAVVGPVTAAPLTRDEVPVVMPERARLGSLARLVTAELPGRASRLTLASGHTVELRGHLVMVDGQVQPLPPAPMAILRALSAAKGRVLTRTELLRCLPRGCDRHAVEMAVTRLRDGLGLRSCVQTVIKRGYRLNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7P2</accession>
    <name>D3Q7P2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019955.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4742"/>
    <dbReference type="EnsemblBacteria" id="ADD44384">
        <property type="protein sequence ID" value="ADD44384"/>
        <property type="gene ID" value="Snas_4742"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4742"/>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_17_0_11"/>
    <dbReference type="OMA" id="GYSCQVK"/>
    <dbReference type="OrthoDB" id="1261526at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="242" mass="25618" checksum="00AB8329C8F7ACF0" modified="2010-04-20" version="1">MTTTPSALVIGAGPGLGMSIAHRFGAGGHRVALVSRSEKRHQGYLDALAAAGVDATAHAADIRDPQQLNAALDAIALEHPRIEVLYYGPGGVDDVFRPVPIAETTSDNVRSAFTWVYPAIDIVQKVLPGMRERGTGSVLIAGGLSGQIPMPALGNLALSAAALRNYALTLNAGLSDMGIYAGTLTIGGLVERGDIYEMVSNDEEMSKMAAGRTLNPDDLADVAWDMHRKRDRPEETFNVLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7P6</accession>
    <name>D3Q7P6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4746</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019959.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4746"/>
    <dbReference type="EnsemblBacteria" id="ADD44388">
        <property type="protein sequence ID" value="ADD44388"/>
        <property type="gene ID" value="Snas_4746"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4746"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069355_0_0_11"/>
    <dbReference type="OrthoDB" id="1267844at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021454">
        <property type="entry name" value="DUF3105"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11303">
        <property type="entry name" value="DUF3105"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="24227" checksum="8BA46F302494AE3D" modified="2010-04-20" version="1">MAKTSSRKNHKGKGKPKRKPTAAKRGIPWWTVSVVALVLVAVGVFGYGIWSQPSAPEDADIDGLVNYKAQKAKWFDDRDHKSGPLKYATTPPAGGNHNATWQTCTGIVYDKPIPNEHAVHSLEHGAIWITYDPGLPQSQIEQLTKKVNGRDYTLMSPYKGQDSPISLQAWGYQLKLSKADDDRIDEFIATYRVEASQEPGATCSGGVTATGDKPVDQPDEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7P9</accession>
    <name>D3Q7P9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1989 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019962.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44391">
        <property type="protein sequence ID" value="ADD44391"/>
        <property type="gene ID" value="Snas_4749"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4749"/>
    <dbReference type="eggNOG" id="COG3665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079904_1_2_11"/>
    <dbReference type="OMA" id="HNINFFM"/>
    <dbReference type="OrthoDB" id="969451at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018959">
        <property type="entry name" value="DUF1989"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09347">
        <property type="entry name" value="DUF1989"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1989" evidence="1">
        <location>
            <begin position="9"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="200" mass="21601" checksum="B3E89841FA8E5B12" modified="2010-04-20" version="1">MTRNWQSHTVEAKSVKAWRLNSGDLLRITDIEGGQTGDLFAVAADDLGDGQSNGRSFDYGGTIRLTTGSTIYSRRSRPLLKIIDDKVGVHDFLYAPCSQEMFEIQYGADGPVPNCFENLSTALAEFGVPASTITIAFNYFMNVDVSTAGKLDIRTPVAVEPGKSMTFAAERDLFVAVTSCPAATCNDGKFQPVVVDIGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7T0</accession>
    <name>D3Q7T0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019993.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4781"/>
    <dbReference type="EnsemblBacteria" id="ADD44422">
        <property type="protein sequence ID" value="ADD44422"/>
        <property type="gene ID" value="Snas_4781"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4781"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_0_2_11"/>
    <dbReference type="OMA" id="MGNPILC"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="228" mass="24818" checksum="7C8A00DE96EFA4B4" modified="2010-04-20" version="1">MPRNTLTSDQIVRAAIELLDAEGLDGLNMRALGARLDSAATAVYWHVKSKDNLVRLAGDRVWGEIKLPDVDENNWRPAALALANSLHAMLTDHAWLGPAFGSYLFYGPGKARFDDRSLAVFEAAGFTPDEADQAAGTVMLFVLASSLSTSMELSLTRRISRAGGDPTEQMRETIAKQSEIAMDYPYLRARLDSTAATDYTAAPDNSFNFGLESILDGFEARLKAKGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Y0</accession>
    <name>D3Q7Y0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glucose-1,6-bisphosphate synthase</fullName>
            <ecNumber evidence="11">2.7.1.106</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_0773</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.106" evidence="11"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016056.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0773"/>
    <dbReference type="EnsemblBacteria" id="ADD40485">
        <property type="protein sequence ID" value="ADD40485"/>
        <property type="gene ID" value="Snas_0773"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0773"/>
    <dbReference type="eggNOG" id="COG1109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016950_0_2_11"/>
    <dbReference type="OMA" id="PQDNGYK"/>
    <dbReference type="OrthoDB" id="637615at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047933">
        <property type="term" value="F:glucose-1,6-bisphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="55"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="220"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="331"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="453"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD40485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="553" mass="58378" checksum="395E0D33856C0264" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q835</accession>
    <name>D3Q835_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0828</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016111.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0828"/>
    <dbReference type="EnsemblBacteria" id="ADD40540">
        <property type="protein sequence ID" value="ADD40540"/>
        <property type="gene ID" value="Snas_0828"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0828"/>
    <dbReference type="eggNOG" id="COG0406">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_5_1_11"/>
    <dbReference type="OMA" id="DPRKRQC"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="215" mass="23493" checksum="46713CA5B0E153AC" modified="2010-04-20" version="1">MSVERTVVHVLRHGEVHNPEKILYGRIPGFHLSALGVQMAEVAAKSLDGLDVTHVVASPLERAQETAAPFAGLFGTGIATDARLIESTNHFEGKRVSVGDGALRDPRNWWVLRDPLKPSWGEPYLHIARRMTTAVMAARRAAAGHQAVCVSHQLPIWTLRCFLTGRRLWHDPRKRECGLASLTSLHFKGAKLVDVTYSEPAASLVTDAAAKIKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q894</accession>
    <name>D3Q894_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamate synthase (NADPH)</fullName>
            <ecNumber evidence="4">1.4.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2792</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.13" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018039.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2792"/>
    <dbReference type="EnsemblBacteria" id="ADD42468">
        <property type="protein sequence ID" value="ADD42468"/>
        <property type="gene ID" value="Snas_2792"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2792"/>
    <dbReference type="eggNOG" id="COG0069">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026563_1_0_11"/>
    <dbReference type="OMA" id="EDHVGMP"/>
    <dbReference type="OrthoDB" id="151647at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004355">
        <property type="term" value="F:glutamate synthase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024188">
        <property type="entry name" value="GltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027283">
        <property type="entry name" value="YerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006429">
        <property type="entry name" value="GOGAT_lg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500060">
        <property type="entry name" value="UCP500060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glu_synthase" evidence="3">
        <location>
            <begin position="155"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="526" mass="56442" checksum="74D62A658D0DA746" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8I2</accession>
    <name>D3Q8I2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2881</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2881"/>
    <dbReference type="EnsemblBacteria" id="ADD42556">
        <property type="protein sequence ID" value="ADD42556"/>
        <property type="gene ID" value="Snas_2881"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2881"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_754217_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="4">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="279"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="367" mass="40355" checksum="5F381077D5058234" modified="2010-04-20" version="1">MPKIVDPTERRTEVVDAVLRIAERDGLEQATLRNIATEAGLAIGSVRHYFTDHAEVMEVAMKELVDRLGARILAKAERVTRPGVDRREAVQSILEEFLPFDAQRRLESAAWLSFVSASRTEPRLRPFAIKMQDGTRTIVGRIVKRIKESGRVPEDFDTDVESDRLTVLIDGLTLRAVLQPDTLDESAARAVLRRHLDSLLESLGRIRFQAEHRLAVVLGDDGLGGVGAVLGGLHLGGDDIVAALRVGAVYGPRVGTVLFGATVDRELLGGVSRVGALPARRDGSEGLHGDDDGQDRHDDRADEQAVAQRRASRPGFGCGRGCQHERRWLVRPLRGGRFGGLRHGRILAVATDTARVTPSRRSRRRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q958</accession>
    <name>D3Q958_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acetyl-CoA acetyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0957</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016238.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0957"/>
    <dbReference type="EnsemblBacteria" id="ADD40667">
        <property type="protein sequence ID" value="ADD40667"/>
        <property type="gene ID" value="Snas_0957"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0957"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_0_0_11"/>
    <dbReference type="OMA" id="DYYWGMG"/>
    <dbReference type="OrthoDB" id="330994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="4">
        <location>
            <begin position="5"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="5">
        <location>
            <begin position="292"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="2">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="414" mass="42877" checksum="DEFC8143B1F4B0C8" modified="2010-04-20" version="1">MTEAVIVATARTPIGRAVKGSLKDLRPDDLAATAVRAALDKVPDLDPAIIDDLYLGCGLPGGEAGFNMGRVVSVLLGYDHLPAATLTRYCASSLQTTRMAAHAIKAGEGDVFISAGVEAVSRYGRGNSDGLPEPVQAQVGGGWQNPVFDAARERSAHRAENGAVGWDDPRESGEVPDIYLAMGQTAENLALARGVTRAEMDAFGVRSQNLAEKAIADGFWAEEITPVTLPDGTVVATDDGPRAGVTLEAVSGLKPVFRPDGRVTAGNCCPLNDGAAAVIVMSDTKAAELGITPLARIVSTGVTAMSPEIMGIGPVEASWQALARAGLGIDDMDLVEINEAFAAQVIPSYQDLGVPLEKLNVHGGAIAVGHPFGMTGARITGTLLHGLQRTGGRYGLETMCVGGGQGMAMVIERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q971</accession>
    <name>D3Q971_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016251.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0970"/>
    <dbReference type="EnsemblBacteria" id="ADD40680">
        <property type="protein sequence ID" value="ADD40680"/>
        <property type="gene ID" value="Snas_0970"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0970"/>
    <dbReference type="HOGENOM" id="CLU_2371413_0_0_11"/>
    <dbReference type="OrthoDB" id="219793at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="95" mass="10722" checksum="1751E1FB0250EB8A" modified="2010-04-20" version="1">MSIRIERDRIEATRAGQWAERVDADSWRVSWLDGDWNRNHAIAALNIAELVAIGPPLGHPYWMNVENFLTELGVDPAVLDNLIDPEPDDEGEDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q999</accession>
    <name>D3Q999_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl-CoA hydratase 2</fullName>
            <ecNumber evidence="1">4.2.1.119</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Enoyl-CoA hydratase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2906</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26526"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57319"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="EC" id="4.2.1.119"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.1.119" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018152.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2906"/>
    <dbReference type="EnsemblBacteria" id="ADD42581">
        <property type="protein sequence ID" value="ADD42581"/>
        <property type="gene ID" value="Snas_2906"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2906"/>
    <dbReference type="eggNOG" id="COG2030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108911_0_0_11"/>
    <dbReference type="OMA" id="TVDQTMI"/>
    <dbReference type="OrthoDB" id="1380653at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03450">
        <property type="entry name" value="NodN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039375">
        <property type="entry name" value="NodN-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC-like" evidence="5">
        <location>
            <begin position="21"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="158" mass="16897" checksum="D42001D32BDC01E9" modified="2010-04-20" version="1">MDFSSLPARPATFDELTALIGVELGPTGWHHVTQEAVNAFARVTGDHQWIHTDPERAADSPLGGTIAHGLYSLSLGPAFSAELLRFDGFAHGLNYGYDKVRFPTPVPVGSRLRMRATVTDATRVPGGVQVTFQQLFDSDAAAKPAVVAVAVARLVEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9A6</accession>
    <name>D3Q9A6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2913</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018159.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2913"/>
    <dbReference type="EnsemblBacteria" id="ADD42588">
        <property type="protein sequence ID" value="ADD42588"/>
        <property type="gene ID" value="Snas_2913"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2913"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_11"/>
    <dbReference type="OMA" id="FPQWGAY"/>
    <dbReference type="OrthoDB" id="1294334at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="247" mass="25174" checksum="CD9C8E0890868479" modified="2010-04-20" version="1">MTRTAIITGASRGIGLGIAQALVDRGDRVCVTARDPETLAEAVETLGGPKSAIGVAGKAHDPAHQDEAIARTVDAFGGIDLLVNNTGTNPVFGPLLDLDLDVARKMVDINLLTVLAWTKKAHAASMGERGGAIVNIASVAGLKPAPGLGFYGVTKAAMIQLTAQLAVELSPGIRVNAVAPAVVKTKFAAALYSGREEQAAAPYPLERLGVPADVAGAAAFLLSEEASWMTGQTLVVDGGLTLMGGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9G4</accession>
    <name>D3Q9G4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2972</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2972"/>
    <dbReference type="EnsemblBacteria" id="ADD42646">
        <property type="protein sequence ID" value="ADD42646"/>
        <property type="gene ID" value="Snas_2972"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2972"/>
    <dbReference type="eggNOG" id="COG2270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017518_3_0_11"/>
    <dbReference type="OMA" id="WAFYDWA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="248"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="442" mass="47837" checksum="0605DABB1F75B8CB" modified="2010-04-20" version="1">MTTTDIVSTPRERAGWYAYDWANSAFPTTVVTAFLGPYLTAIAKVGADGNGDIDVYGLSISAKELWPYVTSLSVILQVVVMPVVGAIADRTSRKKRLLSIMAYTGAASTCGLVFLTGDRYMLGAWLFLIANVSFGASVVVYNSFLPQIAAEPDRDKVSSRGWAIGYLGGGTLLLFNVIAVVLGGSENQADMARWSLVSAGVWWAGFTTLTVAWLRDRPALEGEYRGFVLTAGFKQFWRTLKDMRNYPLSIFFLIAFLVYNDGIQTVFNMAGTYGAEELGFELDALMPVILLVQFVAFGGAMVMGWLAKLYGAKATVLGSLLVWVAIVVFAYFVPAENFAMLLIMGVGIGLVLGGSQALSRSMFSQLIPKGKEGEYFGLYEISDRGTSWMGPLLFGLAIAMTDSYRIAILSLIVFFALGFVLLLLVPVRKAIIAAGNTPPAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9H3</accession>
    <name>D3Q9H3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Triosephosphate isomerase</fullName>
            <shortName evidence="3">TIM</shortName>
            <shortName evidence="3">TPI</shortName>
            <ecNumber evidence="3 4">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tpiA</name>
        <name evidence="5" type="ordered locus">Snas_2981</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="3 4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018226.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2981"/>
    <dbReference type="EnsemblBacteria" id="ADD42655">
        <property type="protein sequence ID" value="ADD42655"/>
        <property type="gene ID" value="Snas_2981"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2981"/>
    <dbReference type="eggNOG" id="COG0149">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024251_2_3_11"/>
    <dbReference type="OMA" id="QEVCGAI"/>
    <dbReference type="OrthoDB" id="1266295at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="11"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="239"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="3">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="27643" checksum="9B8F10C5641837C3" modified="2010-04-20" version="1">MSDRKPLIAGNWKMNLNHFEAIALVQKLAFSLDEKQLSDVEVVVLPPFVDIRSVQTVIDGDNLLLGFGAQDVSAHASGAYTGEISAAMLAKLGCTYVTVGHSERRQYHGEDDKLVGAKAKAALANEITPILCVGEPLPVRESGEHVEHSVGQLLAAIEGLSSEQVDKLVVAYEPVWAIGTGKTCAPDDAQEVIGALRAALAKDHPEAAEKVRILYGGSVKAGNVAQIMKKPDIDGALVGGASIDADEFVKICRFPEHNNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9M6</accession>
    <name>D3Q9M6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020143.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4931"/>
    <dbReference type="EnsemblBacteria" id="ADD44572">
        <property type="protein sequence ID" value="ADD44572"/>
        <property type="gene ID" value="Snas_4931"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4931"/>
    <dbReference type="HOGENOM" id="CLU_737522_0_0_11"/>
    <dbReference type="OrthoDB" id="1576962at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="389" mass="41531" checksum="B869C533CFF02F78" modified="2010-04-20" version="1">MDTETDSPRVDEPETGPSAPVVVDDDRVPLRVKIGWFAGIAAGLVGLGTFQVVSSEANSPEGVVTGFFEALTAGDVDTALTYVEPSAVPIGEEARFLTPAAINRDWKVTAIGDAEANEYQTEFEVEVTIGGPRGTASGSFTVAGDKEDGWLLQDPFAPVIFPRSPLRYPQVNGYIPKPQASREISKGTGYRLFPGMYTFYEDIPETLSVKGVKTLAAFPTGERADYTEGTFHPGRVTAKSKTLASANNRIKTLVDSCAEQSVAEPSGCPFGVGDFVNTSDGKHVEELRSLSWKVEEYPKAGLVDARFDADGDTYENTGFRVLTKTAGAVTLKGTGIDTDDKTTKFSVRCRIDLDSLAATVDPKGVVTLSPLANTETDRGSGSCAKETSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9R4</accession>
    <name>D3Q9R4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4972</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020181.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4972"/>
    <dbReference type="EnsemblBacteria" id="ADD44610">
        <property type="protein sequence ID" value="ADD44610"/>
        <property type="gene ID" value="Snas_4972"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4972"/>
    <dbReference type="eggNOG" id="ENOG5033CGM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1694451_0_0_11"/>
    <dbReference type="OrthoDB" id="1933033at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="155" mass="16806" checksum="52ADC06F85CD083B" modified="2010-04-20" version="1">MTTVRHRLTGSIEVALPPAQAFRLFTPRGEQDWVDGWVPHFPDNPDDDTQPGTVFETNAHGEHTVWVVLDREPGRAISYARTTVGNRAGTVAVLLREAPGGSTVTVSYDLTALSESGRAELDAFAAGYPAFLKSWHDTIRAKITGPQPDNPNIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9R5</accession>
    <name>D3Q9R5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020182.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4973"/>
    <dbReference type="EnsemblBacteria" id="ADD44611">
        <property type="protein sequence ID" value="ADD44611"/>
        <property type="gene ID" value="Snas_4973"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4973"/>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_2_0_11"/>
    <dbReference type="OMA" id="NQRRDQY"/>
    <dbReference type="OrthoDB" id="1033671at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="PTHR43303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="3"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="365" mass="39379" checksum="85F071645CDD0FA8" modified="2010-04-20" version="1">MSSLFTPYTLRSLTIPNRAWMASMCQYSAEPEAAPGVASDWHFAHLAARAVGGTGLILTEATAVSPEGRISPYDLGIWNDTQVAAFQRVTGFLKAQGTVPGIQLAHAGRKASTERTWVDRGRPIGPDEPLGWIPLGPSPIPFSDGYTTPVELTIEAIGEIVGQFADAARRALAAGFEVAEIHGAHGYLVHQFLSPYSNHRTDAYGGSFEGRIRFALDVVDAVRAVWPEELPVLFRLSATDWLAEDPEDDREGWTADDTVRFAKELQAHGVDLLDVSTGGNVPDAKIVTGPGYQVPFAERIRAETGLPVAAVGLITEAHQAEDIVASGKADAVLLGRELLRDPYWVRHAAKELGAEVSAPIQYHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA06</accession>
    <name>D3QA06_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="6">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmA</name>
        <name evidence="6" type="synonym">ksgA</name>
        <name evidence="9" type="ordered locus">Snas_1008</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016289.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1008"/>
    <dbReference type="EnsemblBacteria" id="ADD40718">
        <property type="protein sequence ID" value="ADD40718"/>
        <property type="gene ID" value="Snas_1008"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1008"/>
    <dbReference type="eggNOG" id="COG0030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041220_1_1_11"/>
    <dbReference type="OMA" id="KEEEPYF"/>
    <dbReference type="OrthoDB" id="2030110at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="8">
        <location>
            <begin position="35"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="281" mass="30062" checksum="FFA146BFD7939AC1" modified="2010-04-20" version="1">MTELLGAADIRRIAEALTVRPAKALGQNFVIDGNTVRRIAEAAKLSPDDIVIEVGPGLGSLTLALLPKAKRVHAVEIDARLASALTATVNSRAGDDAAKLRVHHADAMTVAEDGFDEPPTALVANLPYNVAVPVVLHLLASLPSLRQGLVMVQSEVAERLTAKPGTKIYGIPSLKLAWYASARRAGTVPRGVFWPVPNVDSGLVAFERREPPPGDRREVFAAVDAAFAQRRKTLRIALSDWAGGPDRAEAILRAADVDPRTRGEALDITTFARIARERTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAQ2</accession>
    <name>D3QAQ2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyruvate phosphate dikinase PEP/pyruvate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5062</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020269.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5062"/>
    <dbReference type="EnsemblBacteria" id="ADD44698">
        <property type="protein sequence ID" value="ADD44698"/>
        <property type="gene ID" value="Snas_5062"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5062"/>
    <dbReference type="eggNOG" id="COG0574">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3848">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005950_0_0_11"/>
    <dbReference type="OMA" id="EVPEMAY"/>
    <dbReference type="OrthoDB" id="997616at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="2">
        <location>
            <begin position="23"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="1">
        <location>
            <begin position="750"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="840" mass="91186" checksum="E4FE5FFD06F3A0D1" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAZ4</accession>
    <name>D3QAZ4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020361.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5155"/>
    <dbReference type="EnsemblBacteria" id="ADD44790">
        <property type="protein sequence ID" value="ADD44790"/>
        <property type="gene ID" value="Snas_5155"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5155"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_4_11"/>
    <dbReference type="OMA" id="LNHHDLW"/>
    <dbReference type="OrthoDB" id="884088at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="2">
        <location>
            <begin position="13"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="321" mass="33416" checksum="DDB8989FAAA51E81" modified="2010-04-20" version="1">MFAAYASTTDSKAPLSALATGERPEPDRREGWTRVRVEAAALNHHDLWSLRGVGLSAEQCPMILGCDAAGVDEDGNDVIVHAVVADAAAGAGDETLDPKRTLLSEKYDGTLAEYVTVPSGNLIPKPAGLSFAEAACLPTAYLTAYRMLTTKGRLASGDAVLVQGAGGGVSTAAILLAKALGARVYASSRDADRRDSAEALGAIAIEPGGRLPERVDVVIESVGAATIEHSLKCAKPGGRIVVCGTTSGHLANVDLRRLFFLQLELLGSTMGTRGELEALVGLCAERELRPLIDSVYQLTDAAEAFARLESGAAFGKIVLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBE8</accession>
    <name>D3QBE8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Coenzyme A biosynthesis bifunctional protein CoaBC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">DNA/pantothenate metabolism flavoprotein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphopantothenoylcysteine synthetase/decarboxylase</fullName>
            <shortName evidence="3">PPCS-PPCDC</shortName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenoylcysteine decarboxylase</fullName>
                <shortName evidence="3">PPC decarboxylase</shortName>
                <shortName evidence="3">PPC-DC</shortName>
                <ecNumber evidence="3">4.1.1.36</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaC</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenate--cysteine ligase</fullName>
                <ecNumber evidence="3">6.3.2.5</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaB</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="3">Phosphopantothenoylcysteine synthetase</fullName>
                <shortName evidence="3">PPC synthetase</shortName>
                <shortName evidence="3">PPC-S</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="3" type="primary">coaBC</name>
        <name evidence="7" type="ordered locus">Snas_3159</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(R)-4'-phosphopantothenate + CTP + L-cysteine = CMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:19397"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="6.3.2.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine = (R)-4'-phosphopantetheine + CO2</text>
            <dbReference type="Rhea" id="RHEA:16793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="4.1.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="3">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 2/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the C-terminal section; belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.36" evidence="3"/>
    <dbReference type="EC" id="6.3.2.5" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018401.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3159"/>
    <dbReference type="EnsemblBacteria" id="ADD42830">
        <property type="protein sequence ID" value="ADD42830"/>
        <property type="gene ID" value="Snas_3159"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3159"/>
    <dbReference type="eggNOG" id="COG0452">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033319_0_3_11"/>
    <dbReference type="OMA" id="LDMIVAN"/>
    <dbReference type="OrthoDB" id="1346419at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00353"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004632">
        <property type="term" value="F:phosphopantothenate--cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015941">
        <property type="term" value="P:pantothenate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02225">
        <property type="entry name" value="CoaBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005252">
        <property type="entry name" value="CoaBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="SSF102645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00521">
        <property type="entry name" value="coaBC_dfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 4" id="KW-0288">FMN</keyword>
    <keyword evidence="3 4 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="5">
        <location>
            <begin position="10"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="DFP" evidence="6">
        <location>
            <begin position="190"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenoylcysteine decarboxylase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenate--cysteine ligase" evidence="3">
        <location>
            <begin position="195"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="406" mass="41951" checksum="1D761E8AE1E87249" modified="2010-04-20" version="1">MCADAPVRPEVILGVSGGIAAYKACELLRLFTESGHAVTVIPTEAALRFVGEPTWAALSGRPVATGVFDDAHDVPHVQLGRKAELVVVAPATADVMARAVSGRADDLLTATLLTARCPVLFAPAMHTEMWEHPATVDNVATLRRRGAIVAEPASGRLTGADTGKGRLPDPAEIFAFARHLLAGASVGENLRGRHILVTAGGTREAIDPVRYLANRSSGKQGFALARAAAARGAKVTIVAANVSLPVPLGAEVITVESAAQLRSATVEAAAGADAVIMAAAPADFRPASYSDAKIKKDAETTTWSLDLETTVDIAAELGRAKRPGQVLVTFAAETHDAVAHAKAKLAAKNADLMVLNDVSGGKAFGRDDNAVTLLWPDGTSREVALSSKDAIAGAVVDAVAAELRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBP6</accession>
    <name>D3QBP6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3258</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3258"/>
    <dbReference type="EnsemblBacteria" id="ADD42928">
        <property type="protein sequence ID" value="ADD42928"/>
        <property type="gene ID" value="Snas_3258"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3258"/>
    <dbReference type="eggNOG" id="COG4733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014112_0_0_11"/>
    <dbReference type="OMA" id="VGWDTYR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021345">
        <property type="entry name" value="DUF2961"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11175">
        <property type="entry name" value="DUF2961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048845" evidence="3">
        <location>
            <begin position="50"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="228"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="545"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="733"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="930" mass="99085" checksum="7D5496CE9E76302C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBR5</accession>
    <name>D3QBR5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hercynine oxygenase</fullName>
            <ecNumber evidence="1">1.14.99.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gamma-glutamyl hercynylcysteine S-oxide synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">egtB</name>
        <name evidence="4" type="ordered locus">Snas_5169</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>gamma-L-glutamyl-L-cysteine + hercynine + O2 = gamma-L-glutamyl-hercynylcysteine S-oxide + H2O</text>
            <dbReference type="Rhea" id="RHEA:42672"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15781"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:82703"/>
            <dbReference type="EC" id="1.14.99.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; ergothioneine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the EgtB family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.50" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020375.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5169"/>
    <dbReference type="EnsemblBacteria" id="ADD44804">
        <property type="protein sequence ID" value="ADD44804"/>
        <property type="gene ID" value="Snas_5169"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5169"/>
    <dbReference type="eggNOG" id="COG1262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012431_9_2_11"/>
    <dbReference type="OMA" id="CRGTFRN"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="UniPathway" id="UPA01014"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044875">
        <property type="term" value="F:gamma-glutamyl hercynylcysteine sulfoxide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02035">
        <property type="entry name" value="EgtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017806">
        <property type="entry name" value="EgtB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032890">
        <property type="entry name" value="EgtB_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03440">
        <property type="entry name" value="egtB_TIGR03440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="3">
        <location>
            <begin position="15"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="2">
        <location>
            <begin position="171"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Gamma-glutamylcysteine binding" evidence="1">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>gamma-L-glutamyl-L-cysteine</name>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="418"/>
        </location>
        <ligand>
            <name>gamma-L-glutamyl-L-cysteine</name>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="437" mass="49027" checksum="A8FE90479528B752" modified="2010-04-20" version="1">MTDTETLRAHIATVLARARDRTHTLTDAVDETDLIAQHSPLMSPLVWDFAHIGNQEELWLVRDVGGREPVRADIDGMYDAFQNPRRDRPQLPLLRPDEARDYTRVVRDKVFDVLEANALKGHRLVDEGFAFGMIAQHEQQHDETMLATHQLRAGAAVLTAPPPPASRAPVAAEVLIPGGPFTMGTSTEPWALDNERPAHAVHVDAFVIDAAPVTNGQYLGFIEDGGYDDPRWWSDAGWRHRRTENLTAPAHWHPDPGGWLYTRFGVTRPLIPDEPVVHVCFHEARAYARWAGKRLPTEAEWEKSARFDPATGRSRRFPWGDDEPDETRANLGQRHLAPAPVGAYPRGASALGVHQLIGDVWEWTDTDFHGYPGFTAFPYREYSEVFFGDKYKVLRGGSFGTDAVACRGSFRNWDLPVRRQIFAGLRCARDPRPGEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBY9</accession>
    <name>D3QBY9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_5244</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020449.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5244"/>
    <dbReference type="EnsemblBacteria" id="ADD44878">
        <property type="protein sequence ID" value="ADD44878"/>
        <property type="gene ID" value="Snas_5244"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5244"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_454076_0_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="13"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="295"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="406"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="329"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="406"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="421"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD44878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="601" mass="63641" checksum="F70F69950F382F48" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC14</accession>
    <name>D3QC14_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5269</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020474.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5269"/>
    <dbReference type="EnsemblBacteria" id="ADD44903">
        <property type="protein sequence ID" value="ADD44903"/>
        <property type="gene ID" value="Snas_5269"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5269"/>
    <dbReference type="eggNOG" id="COG2229">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077970_1_0_11"/>
    <dbReference type="OMA" id="YPHAADE"/>
    <dbReference type="OrthoDB" id="1438064at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="197" mass="21604" checksum="D15E0DC769F6558B" modified="2010-04-20" version="1">MADRPTNGRVTSAKIVIAGGFGVGKTTLVGSVSEITPLTTEAIMTSAAEKVDDNQLVSDKNTTTVAMDFGRITIDNDLILYLFGTPGQTRFWFMWDELVRGAIGAIVLVDTRRLADSFAAIDFFEHRRLPYLIAVNQFDGKLFHDIEDVREALAVAPQTPIVPCDARQRESTKSVLINLVEYVLSMHRSRTAGAAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU67</accession>
    <name>D3PU67_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor 1</fullName>
            <shortName evidence="5">RF-1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prfA</name>
        <name evidence="8" type="ordered locus">Snas_1304</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Methylated by PrmC. Methylation increases the termination efficiency of RF1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016584.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1304"/>
    <dbReference type="EnsemblBacteria" id="ADD41013">
        <property type="protein sequence ID" value="ADD41013"/>
        <property type="gene ID" value="Snas_1304"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1304"/>
    <dbReference type="eggNOG" id="COG0216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036856_0_1_11"/>
    <dbReference type="OMA" id="ISDHRVG"/>
    <dbReference type="OrthoDB" id="928964at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00093">
        <property type="entry name" value="Rel_fac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004373">
        <property type="entry name" value="RF-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00019">
        <property type="entry name" value="prfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0488">Methylation</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="7">
        <location>
            <begin position="232"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="5">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="367" mass="39951" checksum="184BB739AC4E2927" modified="2010-04-20" version="1">MSQATDSNRLAVLLAEHSELEKQLADPSIHADAALARRVGRRYAELSPIAACNAELDTVKEDLAAAEELAGDDPEFAAEATALRERIPQLEEKLAELLLPRDPDDSRDVIIEIKAGEGGAESALFAADLLRMYLRYAEKHGWVAEIMDSQESEMGGVKDVSVAVKTKGNPEGGHGVWSRMKFEGGVHRVQRVPVTESQGRIHTSAAGVLVMPEAEEVDVEINMHELRIDVYRSSGPGGQSVNTTDSAVRITHIPTGVVASCQNEKSQLQNKEAAMRILRARLLAAKQEEAEAAAGAARKSQVRTVDRSERVRTYNFPQNRVTDHRIGYTSHNLDQVMQGDMDGVLDALATAERAARLEGSDEGLSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUB0</accession>
    <name>D3PUB0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016627.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1348"/>
    <dbReference type="EnsemblBacteria" id="ADD41056">
        <property type="protein sequence ID" value="ADD41056"/>
        <property type="gene ID" value="Snas_1348"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1348"/>
    <dbReference type="HOGENOM" id="CLU_1926279_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003047999" evidence="1">
        <location>
            <begin position="27"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="131" mass="13942" checksum="CF7F29E5379CAB80" modified="2010-04-20" version="1">MRRVRTAIAATVVTAAAILPTVMASGDENSADASGQNWWTSGDSRAGSANFQSDGDLFTVCDEISDGSDVVGKVRDGQDVVYTIVADGGSGDCERRNSGDGNKFDLREGARYTFEVCLSFMDRCQVRTLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUC3</accession>
    <name>D3PUC3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 3">Adenosine deaminase</fullName>
            <ecNumber evidence="1 3">3.5.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2 3">Adenosine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">add</name>
        <name evidence="5" type="ordered locus">Snas_1362</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:28190"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17256"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:28997"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosine + H(+) + H2O = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.4" evidence="1 3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016640.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1362"/>
    <dbReference type="EnsemblBacteria" id="ADD41069">
        <property type="protein sequence ID" value="ADD41069"/>
        <property type="gene ID" value="Snas_1362"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1362"/>
    <dbReference type="eggNOG" id="COG1816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039228_0_0_11"/>
    <dbReference type="OMA" id="NHFTIHA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046936">
        <property type="term" value="F:2'-deoxyadenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009168">
        <property type="term" value="P:purine ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00540">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028893">
        <property type="entry name" value="A_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="PTHR11409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="A_deaminase" evidence="4">
        <location>
            <begin position="12"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="3">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00031852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="360" mass="39382" checksum="2FA541C90F82F946" modified="2010-04-20" version="1">MSLSIEEIRQAPKALLHDHLDGGLRPATVIELAEGIGHELPTTDVTALGQWFVDAANSGSLERYLETFAHTVAVMQTAESLHRVAYECARDLADDGVVYAEVRFAPELHTEAELGLDEVVESVLAGFAAGCADAAREGHQIRVGALLTAMRHAARSMEIAELAVRYRDSGVVGFDIAGAEAGFPPTRHLDAFEYLQRENSRFTIHAGEGFGLPSIWQALQWCGAHRLGHGVRIVDDISFGDDATPTLGRLAHYVRDTRVPLELCPSSNLQTGAADSITEHPIGLLTKLRFRVTVNTDNRLMSGTSLSREMALLSDAFGYGWPELRWFTINAMKSSFIRFDERLAIIDDVIKPAYTKLIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUQ2</accession>
    <name>D3PUQ2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5292"/>
    <dbReference type="EnsemblBacteria" id="ADD44926">
        <property type="protein sequence ID" value="ADD44926"/>
        <property type="gene ID" value="Snas_5292"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5292"/>
    <dbReference type="HOGENOM" id="CLU_112849_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="180" mass="19082" checksum="CE887644298EBFCC" modified="2010-04-20" version="1">MPTEVFGLPLHPLAVHMPVVLVPLLAVVIVAYVLVPKVRRHVGWLLLGLSVVAVAVVFVARASGQQLADETLAEMEGASQQIIEQQAASISNHASNGTTLLWLTLVAAPLAWLFAGFASGRLVSFLKDRSFKPLDATEAASTQRTAIMTTVGVVLVGLAVTMTYFVIRAGHTGAEMIWGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUU9</accession>
    <name>D3PUU9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Isocitrate lyase</fullName>
            <ecNumber evidence="1">4.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Isocitrase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Isocitratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5339</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>D-threo-isocitrate = glyoxylate + succinate</text>
            <dbReference type="Rhea" id="RHEA:13245"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="4.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Can also use Mn(2+) ion.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.1" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020544.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5339"/>
    <dbReference type="EnsemblBacteria" id="ADD44973">
        <property type="protein sequence ID" value="ADD44973"/>
        <property type="gene ID" value="Snas_5339"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5339"/>
    <dbReference type="eggNOG" id="COG2224">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019214_2_0_11"/>
    <dbReference type="OMA" id="LEKDWAE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="PTHR21631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01346">
        <property type="entry name" value="isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="97"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="198"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="319"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00031022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="434" mass="47550" checksum="591AAAB18E354E59" modified="2010-04-20" version="1">MSKPTDLRTRTIEQLELDWRTDPRWQNVTRDYTAEQVVKLRGRVQEEHTLARRGAEKLWAQLTGEAASGGYTNSLGALTGNQAVQQVRAGLRAIYLSGWQVAADANLAGQTYPDQSLYPANSVPQVVRRINNALLRADQIEFAEGASSVEDWLVPIVADAEAGFGGPLNAYELMKSMITAGASGVHWEDQLASEKKCGHLGGKVLIPTSQHVRTLNAARLAADVAGTPTLIVARTDAEAATLLTSDIDERDAEFLTGERTSEGYYRVTNGLPACIARAKAYAPYSDLLWMETGTPDLEVARQFAEAVKAEFPDQMLAYNCSPSFNWKRHLDNDTIAKFQNELGAMGFTFQFITLAGFHSLNHSMFDLAHRYAREGMTAYVDLQEREFAAEDAGYTATKHQREVGTGYFDEIATALNPSGSTLALAGSTESGQFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV92</accession>
    <name>D3PV92_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Potassium-transporting ATPase ATP-binding subunit</fullName>
            <ecNumber evidence="13">7.2.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP phosphohydrolase [potassium-transporting] B chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Potassium-binding and translocating subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Potassium-translocating ATPase B chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">kdpB</name>
        <name evidence="14" type="ordered locus">Snas_1439</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O + K(+)(out) = ADP + H(+) + K(+)(in) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cell membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.6" evidence="13"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016716.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1439"/>
    <dbReference type="EnsemblBacteria" id="ADD41145">
        <property type="protein sequence ID" value="ADD41145"/>
        <property type="gene ID" value="Snas_1439"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1439"/>
    <dbReference type="eggNOG" id="COG2216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025728_2_0_11"/>
    <dbReference type="OMA" id="ILWLWFT"/>
    <dbReference type="OrthoDB" id="237367at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02078">
        <property type="entry name" value="P-type_ATPase_K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00285">
        <property type="entry name" value="KdpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
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        <property type="entry name" value="p-type_atpase"/>
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    </dbReference>
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        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="kdpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="11 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
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    <keyword evidence="8 13" id="KW-0630">Potassium</keyword>
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    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 13" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
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            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
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            <begin position="224"/>
            <end position="249"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="13">
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            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
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            <begin position="612"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="645"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="684"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="13">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="367"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="397"/>
            <end position="404"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="546"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="550"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
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        </ligand>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD41145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="712" mass="75045" checksum="4A04BC7D40924D70" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVB6</accession>
    <name>D3PVB6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">S-adenosylmethionine decarboxylase proenzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Snas_1465</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="ACP-like_sf"/>
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        <property type="entry name" value="S-AdoMet_deCOase_pro-enz"/>
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    <keyword evidence="4" id="KW-0210">Decarboxylase</keyword>
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    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
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    <keyword evidence="6" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
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        <location>
            <begin position="8"/>
            <end position="87"/>
        </location>
    </feature>
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        <location>
            <position position="45"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ADD41169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="213" mass="23060" checksum="27D40E888AD7CFA3" modified="2010-04-20" version="1">MGESRHGNMIAEEIRSLLVEVTGRDELRDIPFDVPLLHEPVALDSISGVRLLRAVHDRYGVDVAAEDLNLDSLASVDALAAFIAERTDQVDGEFARLRKLEAYTPKKLYLVDATYGDSPVLGDAAALESVARSAVEAAGGHVLKDSHVVFPNGAITLVLILAESHLSLHTWPEENLVAIDLFSCGAIEGRIVIDRLTESFGLGEVPVREIDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVB9</accession>
    <name>D3PVB9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1468</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1468"/>
    <dbReference type="EnsemblBacteria" id="ADD41172">
        <property type="protein sequence ID" value="ADD41172"/>
        <property type="gene ID" value="Snas_1468"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1468"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_0_0_11"/>
    <dbReference type="OMA" id="GPNKLRH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="56"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="283" mass="31558" checksum="5ECD3965FFBAD9A3" modified="2010-04-20" version="1">MRCAHCDRPVERGVRGRPRRYCGRSCQARAYRARRDGTARTVARAPGGTGRVVSGRVDREAAVSAAIALADAEGLSAVSMRRLAARLDIAIVTLYRLVSSKDALVSMMMTRVLGQYQPPAAPPPDWRSRLRHEARQEWEMYRRYPWMLPMLATARPPLEGELLAAIDRSMAALYALDVDHRTAMAVYLVVDGFVQGAAQLLITEAESVRDTGMGQRAWWQQQQRRMAAAIDSGRYPWLTALAADDIGQGIDLDEWFAFGLERVLDGVAIWLEPRGVHHPPPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVD0</accession>
    <name>D3PVD0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase S58 DmpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1479</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S58 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016754.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1479"/>
    <dbReference type="EnsemblBacteria" id="ADD41183">
        <property type="protein sequence ID" value="ADD41183"/>
        <property type="gene ID" value="Snas_1479"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1479"/>
    <dbReference type="eggNOG" id="COG3191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024709_0_0_11"/>
    <dbReference type="OMA" id="YWGHGSG"/>
    <dbReference type="OrthoDB" id="2000083at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005321">
        <property type="entry name" value="Peptidase_S58_DmpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36512">
        <property type="entry name" value="PTHR36512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03576">
        <property type="entry name" value="Peptidase_S58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="SSF56266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="318" mass="32545" checksum="8EFB9CF323A1A4A7" modified="2010-04-20" version="1">MPRARDLGLAPGDGDTGEHNAITDVPGIRVGHTTIRRPPDVHTGVTAIDAGATPLRPLPAGFFSGNGYGKFIGSTQVAELGVVESPIVLTSTLSAFRAADALVDWMLARPDCAGVRSFNPVVGECNDGYLSDIRARPVQREDVLSAIATAATGPVPEGCVGAGTGMAALGFKAGIGTSSRLVDLGGTRVSVGALVLANFGGRLRIGGRVIDAPRAEADGSCVVVIGCDARLDARQLNRLARRGVYALGRVGASYSNGSGDYGLALSTSIEGETVDDARLSPLFESTLDCVEEAVLNSLFTATSTVGVDGHVAQAVTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVG8</accession>
    <name>D3PVG8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018653.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3418"/>
    <dbReference type="EnsemblBacteria" id="ADD43082">
        <property type="protein sequence ID" value="ADD43082"/>
        <property type="gene ID" value="Snas_3418"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3418"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086503_2_1_11"/>
    <dbReference type="OMA" id="SKESYWA"/>
    <dbReference type="OrthoDB" id="1389691at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="16010" checksum="0CAFF322DD2B3DD5" modified="2010-04-20" version="1">MITRNDNGYEVDTDVDRIDVDLVHHWLSTDTFWAEGRSRDTVARSIRASENFGLYDSGGALVGYARVVTDLATFAWLCDVYIAPDHRGKGLGTWLAVVIRDHLEPFKLKRVLLSTLDAHGVYAKVGFVPFPDPFKLMILDQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVK1</accession>
    <name>D3PVK1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018686.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3451"/>
    <dbReference type="EnsemblBacteria" id="ADD43115">
        <property type="protein sequence ID" value="ADD43115"/>
        <property type="gene ID" value="Snas_3451"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3451"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_2_3_11"/>
    <dbReference type="OMA" id="VVGCRGQ"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="2"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="150"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="293" mass="31171" checksum="8CB2159372380603" modified="2010-04-20" version="1">MAAPIIVGFDGSPHSQVAVDWAAEEARLRQRRLLIIHSFLVLSPLATDLDSSRHEASRASVGDLVDKEVARIRDLNPDLEVSGKVVGGMSASIDLVEASEDGELLVVGSRGRGRFTSLLLGSTSTQVTAYSRCPVVVVRGPAPVRSQEPDRIVVGVDASPLSQAALRFAFEEASLREARLIAVHAWTHPVATESGDVLPQVYSIEERADSEKRVLAEALAGWPQKYPDVPVERVCERVDARQLLQEKSAGACLVVLGSRGHGGFTGLLLGSTTQAMVHHADAPVAVVHSSGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVW9</accession>
    <name>D3PVW9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Heme chaperone HemW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_5458</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5458"/>
    <dbReference type="EnsemblBacteria" id="ADD45090">
        <property type="protein sequence ID" value="ADD45090"/>
        <property type="gene ID" value="Snas_5458"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5458"/>
    <dbReference type="eggNOG" id="COG0635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027579_1_0_11"/>
    <dbReference type="OMA" id="HIPWCVR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004559">
        <property type="entry name" value="HemW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00562">
        <property type="entry name" value="HemN-like__clustered_with_heat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00539">
        <property type="entry name" value="hemN_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="24"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD45090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="406" mass="43672" checksum="2EDFA18F9481D1E8" modified="2010-04-20" version="1">MPSALPDGEAAPDDGALPDSALKSARSHDFGIYVHIPFCASRCGYCDFNTYTAAELGSGVSRESFPRLLEAEIDLAARVLGDVPRPISTIFFGGGTPSLLPASELTGIVAKLESTFGLTPDAEITTEANPESVDPEYFRQLRAGGFTRVSLGMQSTARRVLAVLERGHTPGRALDAAREAREAGFEHVNLDLIYGTPGETAEDFEASLRAAVDTGADHVSAYSLIVEDGTRLAGQVRRGDIPAPSDDEAADRYLAAERVLGEAGFEWYEVSNWARSEAARCRHNLLYWRGGDWWGLGPGAHSHVGGVRWWNVKHPARYGQRLTDGLSPAQGRELLTPPQRHMEDVLLGVRLADGLALCALDADGQRNARKAAAEGLLDPAALAADRVRLTLRGRLLADAVVRDLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVY0</accession>
    <name>D3PVY0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ComEC/Rec2-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_5470</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020672.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5470"/>
    <dbReference type="EnsemblBacteria" id="ADD45101">
        <property type="protein sequence ID" value="ADD45101"/>
        <property type="gene ID" value="Snas_5470"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5470"/>
    <dbReference type="eggNOG" id="COG0658">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2333">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010363_4_0_11"/>
    <dbReference type="OMA" id="RTDKQGA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07731">
        <property type="entry name" value="ComA-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035681">
        <property type="entry name" value="ComA-like_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004477">
        <property type="entry name" value="ComEC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03772">
        <property type="entry name" value="Competence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00360">
        <property type="entry name" value="ComEC_N-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="507"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Competence" evidence="9">
        <location>
            <begin position="235"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="8">
        <location>
            <begin position="552"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="608"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD45101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="819" mass="84253" checksum="A55461D679DBB807" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVY3</accession>
    <name>D3PVY3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5473</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5473"/>
    <dbReference type="EnsemblBacteria" id="ADD45104">
        <property type="protein sequence ID" value="ADD45104"/>
        <property type="gene ID" value="Snas_5473"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5473"/>
    <dbReference type="eggNOG" id="ENOG5033DHZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141048_0_0_11"/>
    <dbReference type="OMA" id="VEPNCLL"/>
    <dbReference type="OrthoDB" id="1982375at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048627" evidence="2">
        <location>
            <begin position="36"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="139" mass="14333" checksum="1ED461DCFCF280A2" modified="2010-04-20" version="1">MRNKMRQLAKVTTGLLLIAALASCGGKGQPDDAGGSSSSSESSSSASSSDDKDKPDSTESTEGKPDTKAKTLTGTISDGVEPGCLMLKSDGVKYQLVGDATKKLKSGMKVEVTGKVSDNNMSTCMEGTVFEVDTVEKVS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-11-02" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW16</accession>
    <name>MSHB_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase</fullName>
            <shortName evidence="1">GlcNAc-Ins deacetylase</shortName>
            <ecNumber evidence="1">3.5.1.103</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mshB</name>
        <name type="ordered locus">Snas_5506</name>
    </gene>
    <organism>
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate</text>
            <dbReference type="Rhea" id="RHEA:26180"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:52442"/>
            <dbReference type="ChEBI" id="CHEBI:58886"/>
            <dbReference type="EC" id="3.5.1.103"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MshB deacetylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.103" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020708.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D3PW16"/>
    <dbReference type="SMR" id="D3PW16"/>
    <dbReference type="STRING" id="446470.Snas_5506"/>
    <dbReference type="EnsemblBacteria" id="ADD45137">
        <property type="protein sequence ID" value="ADD45137"/>
        <property type="gene ID" value="Snas_5506"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5506"/>
    <dbReference type="eggNOG" id="COG2120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049311_2_1_11"/>
    <dbReference type="OMA" id="IGDYGHP"/>
    <dbReference type="OrthoDB" id="1380748at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035595">
        <property type="term" value="F:N-acetylglucosaminylinositol deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010125">
        <property type="term" value="P:mycothiol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01696">
        <property type="entry name" value="MshB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017810">
        <property type="entry name" value="Mycothiol_biosynthesis_MshB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03445">
        <property type="entry name" value="mycothiol_MshB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000400223" description="1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase">
        <location>
            <begin position="1"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01696"/>
        </source>
    </evidence>
    <sequence length="296" mass="32103" checksum="A1F820660CB3CA93" modified="2010-04-20" version="1">MTDTLPPNRVVFVHAHPDDETIGTGATMAYYAADPDTHVTLVTCTLGEEGEIHVPELSQLAAAEADQLGGWRLHEWHMSCDALGVADRRMLGGPGAYRDSGMMDTPANKHPRAFWGADLTEAAAHLVAILRELRPQVLVTYDPNGFYGHPDHIQAHRVSVKAAELAADADFRPELGEAHKVSKFYWTTVPKSALATMFEEFSQSDDNPFEGVTSVDDLPFGVDDSEVTTVIQGKGFGEAKLASVRAHATQIPPDNWLAVMAAKVGVDATTTEHYILVDGKRGPADPETGWETDLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW38</accession>
    <name>D3PW38_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_5528</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020730.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5528"/>
    <dbReference type="EnsemblBacteria" id="ADD45159">
        <property type="protein sequence ID" value="ADD45159"/>
        <property type="gene ID" value="Snas_5528"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5528"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_11"/>
    <dbReference type="OMA" id="FNTLQMG"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="54"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="374"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="407"/>
            <end position="414"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD45159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="614" mass="67158" checksum="1B5097D9A04AC462" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWI8</accession>
    <name>D3PWI8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3548</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018781.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3548"/>
    <dbReference type="EnsemblBacteria" id="ADD43210">
        <property type="protein sequence ID" value="ADD43210"/>
        <property type="gene ID" value="Snas_3548"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3548"/>
    <dbReference type="eggNOG" id="COG0272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_333130_0_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="909" mass="100202" checksum="F7F592C1B7D34BC9" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWL4</accession>
    <name>D3PWL4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3574"/>
    <dbReference type="EnsemblBacteria" id="ADD43236">
        <property type="protein sequence ID" value="ADD43236"/>
        <property type="gene ID" value="Snas_3574"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3574"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_7_4_11"/>
    <dbReference type="OMA" id="AHTEISR"/>
    <dbReference type="OrthoDB" id="1661714at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="14"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="102" mass="11671" checksum="A68E689F4376150C" modified="2010-04-20" version="1">MPDAANFDDVDYPTYTTGQVARMLTVQQAFLRSLDAADIITPQRSPGGHRRYSRRQVTLIVRLREQLDEGHTLAAAVRITDLQDQLEQAHTEISRLRNQPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWM5</accession>
    <name>D3PWM5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Resolvase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3586"/>
    <dbReference type="EnsemblBacteria" id="ADD43247">
        <property type="protein sequence ID" value="ADD43247"/>
        <property type="gene ID" value="Snas_3586"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3586"/>
    <dbReference type="eggNOG" id="COG1961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_686783_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011109">
        <property type="entry name" value="DNA_bind_recombinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07508">
        <property type="entry name" value="Recombinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="1">
        <location>
            <begin position="25"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="401" mass="45717" checksum="A49086E7AD644B31" modified="2010-04-20" version="1">MTSAPIDLSTLPGYSWDTSTRAHITAFLGRCSTKDQQDPTTSIPGQATVCARRLGQGEDFAAYFWDVESGYMHLNARSQHDDDYYAELAVPLRRDGGLTDLLAAAHAGEITRVICERSDRAARDMLTILTVESHLEQWGVELVYATEPPPQRPGDMPASRLRMRRGQQMDAEIYRALMLENSERGQREHAAQGYSHGPAPYPYIAVIDPDAPARHDRYIRRPKRRLQPHPGPHRWDTSVHMARLRLEDARYRDIRIALNADPEKYPHDKPGGQWTDRRIRSLLLNPRLTGYAVFNRRSSKNGFTPIPMQEWTWSRQPSHKAVFTVDEWVQMVRMDAADRAPRDALERVRAAAHQHGYLLREVRSNDTHIVYAIGSREFTVPHGVLPEPAAEHIITWLETAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWR2</accession>
    <name>D3PWR2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycosyl hydrolase family 32 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3624</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3624"/>
    <dbReference type="CAZy" id="GH32">
        <property type="family name" value="Glycoside Hydrolase Family 32"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43284">
        <property type="protein sequence ID" value="ADD43284"/>
        <property type="gene ID" value="Snas_3624"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3624"/>
    <dbReference type="eggNOG" id="COG1621">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001528_3_1_11"/>
    <dbReference type="OMA" id="HDIARTW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013189">
        <property type="entry name" value="Glyco_hydro_32_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08244">
        <property type="entry name" value="Glyco_hydro_32C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048655" evidence="5">
        <location>
            <begin position="34"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_32N" evidence="6">
        <location>
            <begin position="55"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_32C" evidence="7">
        <location>
            <begin position="370"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="489" mass="53988" checksum="CB5F915141CE7C19" modified="2010-04-20" version="1">MRPRLSRRQLLMLSATVAGGTGMAALGVAPAFAADYPEFPYPDTDYQEPTRGQFHFSSQGGWMNDINAPLYYDGTYHLFYQHNPHGLTWDTMHWGHATSPDLVHWTQQPIALEPGIHPGDLWSGAGLVDFDNHTGLQTSNTPPIVVFSGTNGVRLFYSNDRAKTFQTYDNGNPIATPAGTSRDPKVFWHTGTNEFKLVIWTDAGGNGVDIFSSPNLLDWTFKSRFAADWLFECPDLFPLPYNDGYKWVLNDASGDYVVGTFDGTSFNPETTVARMVEGRGAFDGTFYAGLTFAHPPGDRIIQMLWMPGNRGDIWTGCATFPVELALRETSDGPRVTRNPIAAIEGLRFDTHRYGPAVVDPGQAEALLRDVVTQECEIIAEFDADSSTATRFGFRLDVNEDGSGGHEVLYDKTAQTLYGAALPTSEGKVRMRLLVDRNHLEIFGNDGTMSYIDSPSFSTSDQTYRLRLYADGGTVSVASIAVHDIARTWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX07</accession>
    <name>D3PX07_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_5601</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020802.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5601"/>
    <dbReference type="EnsemblBacteria" id="ADD45231">
        <property type="protein sequence ID" value="ADD45231"/>
        <property type="gene ID" value="Snas_5601"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5601"/>
    <dbReference type="eggNOG" id="COG0411">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006313_3_0_11"/>
    <dbReference type="OMA" id="FWIVLLD"/>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="306"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="338"/>
            <end position="345"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD45231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="563" mass="59117" checksum="BE3401883C4C79A9" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX66</accession>
    <name>D3PX66_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1626"/>
    <dbReference type="EnsemblBacteria" id="ADD41329">
        <property type="protein sequence ID" value="ADD41329"/>
        <property type="gene ID" value="Snas_1626"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1626"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_623900_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049528" evidence="2">
        <location>
            <begin position="31"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="439" mass="46915" checksum="A5F4EDE65BFB64D9" modified="2010-04-20" version="1">MNPVARKRNGISRMAIAVAAAVALLSTSCSSESDTEVPSALTSAESEGEKEKSRTDPIEFSEKPLWSKKPLDEDGSDSLRFSGTSVLGDKVAFVRRDNESAEHLTVAKAKSGKTVWELTDGDTIKGSDGLRADHPEVDPLGGADAEALLVAYVKPTTLADGSSGEENGIAALSLKDGSMLWSVPVVTGPQHGYFMFLAATSDSHVAVDLSDHSGEEDVSKLVMVDYKKREVVWQKEWLEAAAIIDDTVIVDKFKPDGDNLDHVTAMGLKVSSGKTRWELDHDKDPDVLTATNDAAVVDSGGSVLILDPKSGDQRAKLAIAATECYFDGESTLACQSSKDTDSAPASVISIIEVTDSTAKASQVSGTDRDELSGIYKGRIFVERLVDQRNELTVLDTSGKTIAEQLPGSLADITDDYAAFVRIAENFAETDIMSVHKVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX95</accession>
    <name>D3PX95_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016929.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1656"/>
    <dbReference type="EnsemblBacteria" id="ADD41358">
        <property type="protein sequence ID" value="ADD41358"/>
        <property type="gene ID" value="Snas_1656"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1656"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="PYWHQRQ"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="328" mass="35770" checksum="C75FDA07435F6FE5" modified="2010-04-20" version="1">MEYVNLGRTGLKVSPLCLGTMNFGPITSEADSHTIMDAALERGLNFFDTADVYGWQRGEGITEKVLGTWFAKGEGRRDAVVLATKAYGPMGDGPNDRGLSARHLIAACEASLKRMQTDYIDLYQMHHVERSTPWEEIWQAMDLLVSQGKIRYVGSSNFAGWHLVAAQEAANRRNSLGLVSEQGLYNLMARTVELEVLPAAEAYGIGFLPWSPLNGGALSGALRKIAEGKAGRSATGPGNERVEENREQLAAWEKFCEEFGHDPADVGLAWLLTRPAVTAPIVGPRTIEQLDSTLGCLDVQLDDEQLDKLDELFPPVGKGGPGPEAWAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX99</accession>
    <name>D3PX99_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016933.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1660"/>
    <dbReference type="EnsemblBacteria" id="ADD41362">
        <property type="protein sequence ID" value="ADD41362"/>
        <property type="gene ID" value="Snas_1660"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1660"/>
    <dbReference type="eggNOG" id="ENOG502ZCEB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072365_0_0_11"/>
    <dbReference type="OMA" id="HHDIFAK"/>
    <dbReference type="OrthoDB" id="1861154at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="134"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="267" mass="29983" checksum="752013BAC50EDF2E" modified="2010-04-20" version="1">MSNVNSHDPFFTPVTAEAFRREDIAALAAGRHAAIRVPEFLSQSTCDEILQALLAVEFESYGSARVYPQVMRFGVGVSDHRLDGGVDDSYWDAIETDRKNWLDLGLNFDPFHLCRANLGTDWPKAVRVGTRDGKPMGPGVAREPNQGFQVHFDDSRREYSDGLLDANLIAQFAFNLYLTMPEEGGETVMWRHRWQPQDENYRLPDSYGYHESVVGDVESFEIKPRAAEAILLDPGYFHAVRPSRSARRIALGFAVGLTDTGELLTWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXF7</accession>
    <name>D3PXF7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016991.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1722"/>
    <dbReference type="EnsemblBacteria" id="ADD41420">
        <property type="protein sequence ID" value="ADD41420"/>
        <property type="gene ID" value="Snas_1722"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1722"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_3_2_11"/>
    <dbReference type="OMA" id="MENNQSC"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018334">
        <property type="entry name" value="ArsR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00846">
        <property type="entry name" value="HTH_ARSR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="23"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="116" mass="12495" checksum="AE1922A8A4D884F5" modified="2010-04-20" version="1">MADPTLTAPIPVSCCAPLAETALDDERAVGLSAMFKALGDPVRLRLLSLITSAPDEICVCDLTGAFDLTGATISHHLKVLRTAGLVDCERRGTWVYYWPLRDNLRKLSALLDSPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXP9</accession>
    <name>D3PXP9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3722"/>
    <dbReference type="EnsemblBacteria" id="ADD43379">
        <property type="protein sequence ID" value="ADD43379"/>
        <property type="gene ID" value="Snas_3722"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3722"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027938_4_1_11"/>
    <dbReference type="OMA" id="QWGAHEV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="20"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="230" mass="25145" checksum="771B6E0F4AB51758" modified="2010-04-20" version="1">MFCRLRITGEIPGELRKSSMILAANHIGTFDPFVLIAACARKGLAPRFLATAGLFRAPVFGSIMRGCGHIQVDRGKHTVTEALHNAIDALDEGSCILIYPEGRVTLDPGLWPENGKTGVARLALTSKAPVLAISQWGAHEVMAYDTPGAIARSLLTALWRRPIARVHFAGLVDLSGPDMTPRKATDRITEHYLDALPPLRADEPVLPRHIDPIRPLSSARTYRRPKPPDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXS1</accession>
    <name>D3PXS1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">CDP-alcohol phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Snas_3744</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018972.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3744"/>
    <dbReference type="EnsemblBacteria" id="ADD43401">
        <property type="protein sequence ID" value="ADD43401"/>
        <property type="gene ID" value="Snas_3744"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3744"/>
    <dbReference type="eggNOG" id="COG0558">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051314_6_1_11"/>
    <dbReference type="OMA" id="GTTLYWW"/>
    <dbReference type="OrthoDB" id="1702107at2"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000847">
        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD43401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="201" mass="21855" checksum="5350730538939DFD" modified="2010-04-20" version="1">MTGRELGDTTAWRVWTVPNLITMVRLAGIPVFCYLLLATDSYVAAVVVLAVGGGTDWIDGFLARRLGQESRFGQILDPIVDRLYILVAVGALTITGLLPWQFTLVLLAREAVMLATVVAVRRSGYAPLKVHFVGKTATFILFSSLPTLALAGLYEPAEGWALPLGWALAWWGIVLYWLSVVLYLAQAIPLLRAARTPAGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXU3</accession>
    <name>D3PXU3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3766</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018994.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3766"/>
    <dbReference type="EnsemblBacteria" id="ADD43423">
        <property type="protein sequence ID" value="ADD43423"/>
        <property type="gene ID" value="Snas_3766"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3766"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1324180_0_0_11"/>
    <dbReference type="OMA" id="QWSERRK"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="18"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="200" mass="21871" checksum="92EEE504B9B3207B" modified="2010-04-20" version="1">MADTQAGYRRSTGTPRGNARRDELLELVTDDLAANGLADFSLRRAARAAGTTHKVLLYHFDGAEDVLAQAVRQLRQRRIDKAALTAIAERPTLAERVAEIWPILIGAESAVLSQAMGLAMQDPVRYADLGREATGQYIPVLKSLCPTEWSDERKTGVSQMILATMRGFLMHRRVTGDEEGPETGLAALVRAIEREEAAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXW8</accession>
    <name>D3PXW8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020868.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5667"/>
    <dbReference type="EnsemblBacteria" id="ADD45297">
        <property type="protein sequence ID" value="ADD45297"/>
        <property type="gene ID" value="Snas_5667"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5667"/>
    <dbReference type="eggNOG" id="COG1887">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_465163_0_0_11"/>
    <dbReference type="OMA" id="FNASDAM"/>
    <dbReference type="OrthoDB" id="1159548at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047355">
        <property type="term" value="F:CDP-glycerol glycerophosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007554">
        <property type="entry name" value="Glycerophosphate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043148">
        <property type="entry name" value="TagF_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04464">
        <property type="entry name" value="Glyphos_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="551" mass="59604" checksum="21BC1BC8C3A8DA34" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXX9</accession>
    <name>D3PXX9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="4 7">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Snas_5678</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="4 7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020879.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5678"/>
    <dbReference type="EnsemblBacteria" id="ADD45308">
        <property type="protein sequence ID" value="ADD45308"/>
        <property type="gene ID" value="Snas_5678"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5678"/>
    <dbReference type="eggNOG" id="COG1004">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023810_1_2_11"/>
    <dbReference type="OMA" id="SYINAMA"/>
    <dbReference type="OrthoDB" id="647136at2"/>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028357">
        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500134">
        <property type="entry name" value="UDPglc_DH_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="11">
        <location>
            <begin position="355"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="175"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="281"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD45308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="474" mass="51505" checksum="68C777E6807C800A" modified="2010-04-20" version="1">MRASSTSLPNEGESIVASGSPRPRLTFIGVGPLGGTYAACYAELGYEVLGYDVDSGRIEKFSAGEMPFYERGLDDLVRKNVDNGRLRFTTDPQEVADFGDVHFLCVGTPPRKDSDSADLAYIESAVTTLAPLLTRRCLLVGKSTVPVGTAAWVQQLIDKHSSPDVEVEVAWSPEFLQEANAVDDVLRPNRIVLAAQSEWADELLQAAHKGVFELAAMEDREVPLVKTDFATAELVKVASNAFLSTKISFINAMAELCEASGGDVNALARAMGYDSRIGHRFLRAGIGFGGGCLPKDLRALAARGKELGVGESMRFLAEVEDINLNRRTKVVRLAAELCGRENGPNGPELSGLNITVLGATFKPDTDDVRDSPALDIARRMSNEGATVTVYDPMGMDNARMFRPELRYGHTLTEAVEGADLVCVLTEWEEFRHVDPEALSDLVAKPRILDGRNALDPQLWRNAGWTYRGLGRAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXZ0</accession>
    <name>D3PXZ0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5689</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020890.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5689"/>
    <dbReference type="EnsemblBacteria" id="ADD45319">
        <property type="protein sequence ID" value="ADD45319"/>
        <property type="gene ID" value="Snas_5689"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5689"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_0_11"/>
    <dbReference type="OMA" id="MAVEWLP"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049345" evidence="2">
        <location>
            <begin position="22"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="HTH lysR-type" evidence="3">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="314" mass="34190" checksum="1241C4380D52D13D" modified="2010-04-20" version="1">MIDLRRLYVLRAVSHYGTVTAAAKALHLSPSAASQQIRQLAKELDVTLLEPQGRNVRLTPAAHVLLSHADAIEARWRRAETELHATGAEPAGELRLCGFATAIATLLAATAELLHARYPAMDVRLREAEARECFDLLFSGDADLAIVEANFESPPLDDIRFDQQPLFDDPFDLVTAADHPLAERDSVALTDTARERWILGLPGSTSRQHVLAACSNAGFTPSVAHEAGEWSVAATLVAHNLGIALVPRLAELPPHLALSRVPIAGPHTPYRHFLSCTRRGSREYPTIAAASEAIEEIRAERESVEEGLNNTLIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY20</accession>
    <name>D3PY20_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020920.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5719"/>
    <dbReference type="EnsemblBacteria" id="ADD45349">
        <property type="protein sequence ID" value="ADD45349"/>
        <property type="gene ID" value="Snas_5719"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5719"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_9_2_11"/>
    <dbReference type="OMA" id="IAQHCIL"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="352" mass="38334" checksum="9C578525AACEBAC8" modified="2010-04-20" version="1">MTPKSAAPVLVTGATGYIAGHVIKELLANGYIVRGTVRDTSATHKTAHLRALPGGERLEFVAADLTRDDGWAKAVDGCEYVMHVASPLPNHTPKNEDEVIRPAVDGTLRVLRACADDPGVKRVVLTSSIAAIRIGHPDDGRARTEDDWSNLDKCPVYPKSKTLAERAAWDFMADKGSAAGFELVAVNPGLVLGPLLNDDSSTSVETLRKLVNRELPGSPRLGFAVVDVRDVAIAHRLALETPAAAGNRYIVAGEHLWLKDMASILAAEFNPRGYRIPTRAIPNWVMWLAARFDKTARLALDFINVREHLSADKARRELGWSMRPVDETLIATVDSMIELGMVRDREKASARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY70</accession>
    <name>D3PY70_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5769</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020970.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5769"/>
    <dbReference type="EnsemblBacteria" id="ADD45399">
        <property type="protein sequence ID" value="ADD45399"/>
        <property type="gene ID" value="Snas_5769"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5769"/>
    <dbReference type="eggNOG" id="COG0400">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081826_0_0_11"/>
    <dbReference type="OMA" id="GWAYLRQ"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="248" mass="26036" checksum="8B6C911A31F27617" modified="2010-04-20" version="1">MVTTLVRGSGEPVTVFAHGLGADIADTRPLGSGVDGTKVFYTARAHDGVAVERFDYAVLAADLRAVADEHDATRALGVSMGAGALCHLIAETPDRFARLVFFLPAVVDEPRADVARLRLTALDEAVAHGDGDAAAALIAAELPASVRDTPAGRAYAAARAKILCQPSMRGIPARLAGQVAVADPAALSRVTAEALVLGCEGDAAHPAAVARRLAELLPSSRLHIFEDPNVMWTHRTELRERIGHFLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYC4</accession>
    <name>D3PYC4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1794</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017062.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1794"/>
    <dbReference type="EnsemblBacteria" id="ADD41491">
        <property type="protein sequence ID" value="ADD41491"/>
        <property type="gene ID" value="Snas_1794"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1794"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040779_0_0_11"/>
    <dbReference type="OMA" id="GSVWRAW"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="391"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="8"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="285"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="416" mass="42048" checksum="448235CEE8D3B2DD" modified="2010-04-20" version="1">MEIFAGRYHLVDPIADGGMGSVWRAWDAKRGGYVAAKLLRPSDAASLLRFVREQALRVSHPNVVAPHGWAAEDELVLLTMDLVGGGSAHQLIGDYGAIPVPYAAVLVDQLWSALTEVHAHGIVHRDVKPANLLLEVTGRAAPVLRLADFGIAAVTGQPRLTEASVIVGTPGYLAPEALLDTQPHPTHDVYATGVVAWRLLTGLTPPPEGPAVDPQHPPTNVPAPVWRAVATFTEPDPQQRPSSAADAWRAWREALSAAAVPAVDANRPDAVEVFDQLGPLPDGFAPSGPVRLAPAPPLSPAFGGAQAGAGEAEGVPPSSGAGAGAQPSPGSGAGAEGAPPGSGAGAVSSASGQGQAATGRPTQAVRPSSGAGAGPQLPPTKSMRASGGRRVVLGIALGLAALGAVILAVSLVLLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYG3</accession>
    <name>D3PYG3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FacC-like extracellular signaling protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017101.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1834"/>
    <dbReference type="EnsemblBacteria" id="ADD41530">
        <property type="protein sequence ID" value="ADD41530"/>
        <property type="gene ID" value="Snas_1834"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1834"/>
    <dbReference type="eggNOG" id="ENOG5032EYX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052172_0_0_11"/>
    <dbReference type="OMA" id="ATYLWTE"/>
    <dbReference type="OrthoDB" id="889359at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049562" evidence="1">
        <location>
            <begin position="43"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="348" mass="37495" checksum="D399EF029E055BC7" modified="2010-04-20" version="1">MPPSTPRSPKFSRRGLLAAGGGATVLAGLGASFGLGAASASADTAVPPSGKFDLTAPSNRLFWKKPLHNVTVMQCFSFDNAKGHLYTLQVTQGSSPAQGNLTMTQLDLTGKKLGRMYLKGFGHGISFGVQPTSSGPVMWTEAVIGPGDRATKVCRFRFRNTTTPITQDDVELFTPIEGMRSASCSLDLDHNTIAVRYIKDGLDSMHVSLYDFTKFAAGDFSAPLTDISLGQVHPPGITPQGYQHYGQHLYLFQGNAYYYDEGTAEEHCDVTHPDGELDGNAKVSRINFNDPSDHETHLTKAGFSLNFREPEGLGLLKLDGKPRLCMGFASGCAGSRLANVYYKDSDPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYV5</accession>
    <name>D3PYV5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019109.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3883"/>
    <dbReference type="EnsemblBacteria" id="ADD43538">
        <property type="protein sequence ID" value="ADD43538"/>
        <property type="gene ID" value="Snas_3883"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3883"/>
    <dbReference type="HOGENOM" id="CLU_1593550_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048100" evidence="2">
        <location>
            <begin position="28"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="167" mass="17072" checksum="2186CC7F3FD4C89C" modified="2010-04-20" version="1">MRTPTRLGFVALVLALSAGACDSGDNAAANPSATADPTTATRPDTDAGASEKEDEPGSAPESAKTTEPEPSASDDATDGLSQSQRELLAKARRDGEVMVIVSMAEGSQTRRYDRVAEGVSDSGGAVTGGSDVDDSWLSAMAVEDTLWFLFGSGDVASVVEDGLSEPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ05</accession>
    <name>D3PZ05_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Adenylylsulfate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5804</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021005.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5804"/>
    <dbReference type="EnsemblBacteria" id="ADD45434">
        <property type="protein sequence ID" value="ADD45434"/>
        <property type="gene ID" value="Snas_5804"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5804"/>
    <dbReference type="eggNOG" id="COG0529">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2046">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022950_0_1_11"/>
    <dbReference type="OMA" id="WHTPPAV"/>
    <dbReference type="OrthoDB" id="1574819at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025980">
        <property type="entry name" value="ATP-Sase_PUA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024951">
        <property type="entry name" value="Sulfurylase_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01747">
        <property type="entry name" value="ATP-sulfurylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14306">
        <property type="entry name" value="PUA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA_2" evidence="6">
        <location>
            <begin position="15"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-sulfurylase" evidence="5">
        <location>
            <begin position="134"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="509" mass="54450" checksum="7C471FB766E2E638" modified="2010-04-20" version="1">MVSDWVLPDEVLADAPSYTPRPHELADLELLLSGAYAPLNRFLGTEDVDSVAAAGTLADGTQWPTPVTLHVPADTVSSLDSSSPMSRVLVLTDPEGVPVAAVDAVELTPVGDGSVRVAGPVRRIGEVLHGPFRRLRATPAATRETLTTQRVLGVIADRPLHRPQLAEISRAAHTLAAHVLILIPVAGLGPDGLPPAVLVRSIMAARDRLPKSTIVAVPLSQRGDDVRDGLLSSRVAAAYGATHLLSMGRSFAAGGSGVRIMLPRQLCYDARDGQWRALEDVEPPFRRQAMSPSEISDMLDRGFGLPDWHTPPAVAAELRRARPPRRKRGVVVFMTGLSGSGKSTIARGVYDALLETGERTVSLFDGDVVRRLLSSELGFSGTDREANIRRIAYVASEVAHHHGVALCCPIAPYAAGRAEARRMAAEAGADFILVHVSTPLEVCEERDRKGLYAKARAGVIESFTGITDPYEVPKNADLTVDTSEIAVDEAIGQVIDYLVDGGWIETVPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZC0</accession>
    <name>D3PZC0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">O-methyltransferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1898</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1898"/>
    <dbReference type="EnsemblBacteria" id="ADD41594">
        <property type="protein sequence ID" value="ADD41594"/>
        <property type="gene ID" value="Snas_1898"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1898"/>
    <dbReference type="eggNOG" id="COG3315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069348_2_0_11"/>
    <dbReference type="OMA" id="WGSVEWT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016874">
        <property type="entry name" value="TcmP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028177">
        <property type="entry name" value="Polyketide_synth_Omtfrase_TcmP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="273" mass="30914" checksum="362F3589A336D5AE" modified="2010-04-20" version="1">MEVMADTELTGVKRTLAVVLQTKAVDNLLPEPILGDAYAERAMRGLDPDYDKRKRGTSQMGAMAVVRAKAHDDWARAFLAEHPDAVVLHLGCGLDARVYRVDPPAGVDWYDLDFPDVIALREQLLPRREHYTLIGSSVIELAWLDRVPHDRPVLMIAEGLLPYLEAADVERIVTSIVDGFPSGQLQCDLVPPWVSRTSKYDPNLRKYGVTFKSGFKPRVLADWHPRLEYLDEAPILNSPDLARLPASVRFTYWLMNVTPGLRTSYRVERYRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZQ9</accession>
    <name>D3PZQ9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA polymerase-binding protein RbpA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rbpA</name>
        <name evidence="2" type="ordered locus">Snas_3943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a complex with the RNAP catalytic core and with free principal sigma factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase-binding protein RbpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019167.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3943"/>
    <dbReference type="EnsemblBacteria" id="ADD43596">
        <property type="protein sequence ID" value="ADD43596"/>
        <property type="gene ID" value="Snas_3943"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3943"/>
    <dbReference type="eggNOG" id="ENOG5032SI2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134276_0_0_11"/>
    <dbReference type="OMA" id="VWECRCG"/>
    <dbReference type="OrthoDB" id="1912152at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001000">
        <property type="term" value="F:bacterial-type RNA polymerase core enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01483">
        <property type="entry name" value="RbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038638">
        <property type="entry name" value="RbpA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025182">
        <property type="entry name" value="RNApol-bd_RbpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13397">
        <property type="entry name" value="RbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="112" mass="12956" checksum="142EC56A6EA3BBBC" modified="2010-04-20" version="1">MSERMLRGSRLGAISYESDRNTELAPRQTRDFVCARGHRFEVPFAVEAEVPATWECRLDGTVAKLVDGEEPEGKKAKPPRTHWDMLLERRSTDELEEILKERLAEMRARRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZV0</accession>
    <name>D3PZV0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polar amino acid ABC transporter, inner membrane subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3985</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019208.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3985"/>
    <dbReference type="EnsemblBacteria" id="ADD43637">
        <property type="protein sequence ID" value="ADD43637"/>
        <property type="gene ID" value="Snas_3985"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3985"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_0_11"/>
    <dbReference type="OMA" id="IWTFVWI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="16"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="220" mass="23445" checksum="8FF54F5314ECB113" modified="2010-04-20" version="1">MFQNLDYVLPILAQGFVTTLWLTLASFALALVIGGILALMHVSPAPPARWAATAYTQFFRNIPLLVILVLFLFGFTALGIGKGMASWIWAIIGLGTYTGALVGETLRSGINSISLGQAEAARSIGLTFGQSLSSVILPQAFRTVVPPLGSLFIALVKNSALASAVGIIELSGVADQLQEDRNVSVSIWTIVIGVILFYLIINLPASYLIRVAEKRAAISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZX8</accession>
    <name>D3PZX8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UDP-N-acetylmuramoylalanine--D-glutamate ligase</fullName>
            <ecNumber evidence="9">6.3.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">D-glutamic acid-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">murD</name>
        <name evidence="11" type="ordered locus">Snas_4013</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the MurCDEF family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.9" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019236.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4013"/>
    <dbReference type="EnsemblBacteria" id="ADD43665">
        <property type="protein sequence ID" value="ADD43665"/>
        <property type="gene ID" value="Snas_4013"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4013"/>
    <dbReference type="eggNOG" id="COG0771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032540_0_0_11"/>
    <dbReference type="OMA" id="CNFENYL"/>
    <dbReference type="OrthoDB" id="1093223at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008764">
        <property type="term" value="F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00639">
        <property type="entry name" value="MurD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005762">
        <property type="entry name" value="MurD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01087">
        <property type="entry name" value="murD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8 9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="10">
        <location>
            <begin position="109"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="111"/>
            <end position="117"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD43665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="454" mass="46785" checksum="8161834D9472906E" modified="2010-04-20" version="1">MGHYLVVGTGIAGAGAARALAARGHEVIVYDRVESDGLAALAPLVTDTVSGEDPPREALARVDEVVVSPGIPPHHPLVLAAQDAGLEVYSEPELAWRLRPADAAPWLAITGTNGKTTAVTMLASILTAAGLKTAALGNIGTPLVDAVTADYDVLAVELSSQQLHWSKQLSPRVGALLNLADDHLSWHGDFDAYSHAKTAIWRGDVHIGNADDPRVSALLKDAPGDTPITFTLGEPSPGQFGVRDGKLVDNTGTAPVALCDVAAIRPTGIHNVANALAATAVARAFGVPAEAVAAGFASYVPEPHRNVEIATVGGVRYVDDSKGTNPHATAAAIEAYDPIVWIAGGQLKGVDVETLVERAAPRLRGAVLLGVDRAILAGLLAKHAPDVPVVTIDRTDPEAMTDAVTAAAAMARPGDTVLLSPAGASYDMFTGYPDRGRRFAAAVAELDDGPGPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q095</accession>
    <name>D3Q095_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LAO/AO transport system ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5998"/>
    <dbReference type="EnsemblBacteria" id="ADD45624">
        <property type="protein sequence ID" value="ADD45624"/>
        <property type="gene ID" value="Snas_5998"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5998"/>
    <dbReference type="eggNOG" id="COG1703">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043725_1_0_11"/>
    <dbReference type="OMA" id="DWRPPIV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005129">
        <property type="entry name" value="GTPase_ArgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00750">
        <property type="entry name" value="lao"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="307" mass="32460" checksum="CE53A167A59CC27D" modified="2010-04-20" version="1">MSDIENLARRAADGDPRALGRLITVVENGGEGVRAVAATLAPLTGQSQVIGLTGSPGVGKSTTTTALVSTFRSAGKRVAVLAVDPSSPFTGGAILGDRVRMQEHALDEGVYIRSMSSRGHLGGLAAATPQAVRVLEACGFDVILIETVGVGQAEVEIAGLADTTLVLLAPGMGDGIQAVKAGILEVADIFVINKADRDGADATFRDIRSMMALVTREPHEWRQPIVKTIAHREEGIDEVVGAIEKHHQWLDEHGELRRRREARAKAEISAIVLGALARKYRVDETLAGRVAGGELDPYAAADEILDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0C1</accession>
    <name>D3Q0C1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015356.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0063"/>
    <dbReference type="EnsemblBacteria" id="ADD39785">
        <property type="protein sequence ID" value="ADD39785"/>
        <property type="gene ID" value="Snas_0063"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0063"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100243_0_0_11"/>
    <dbReference type="OMA" id="YTAWVLE"/>
    <dbReference type="OrthoDB" id="1631193at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009339">
        <property type="entry name" value="DUF998"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06197">
        <property type="entry name" value="DUF998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="225" mass="23336" checksum="9BE140F05C3621FF" modified="2010-04-20" version="1">MAIALLASGVVYASWLLGGWVNPGLGPVVSYASELAASDQPGSLAFRIGDLVAGAAACVAGLWALRRRPWLGWACVVAFGVFTMLDAGLFNMSCAPSLDPTCATAEVAGKVPLRHQIHTLSSSLAAAAPFVGLIAFAWAWRTVTAWVLSGLMVAATAATMLAVATDHLVGVAQRLQLLIVSAWLVWLALRTWRATSSDPTAARTATANLAPSEQPTAVDTNGARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0D3</accession>
    <name>D3Q0D3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent pyridine nucleotide-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015368.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0075"/>
    <dbReference type="EnsemblBacteria" id="ADD39797">
        <property type="protein sequence ID" value="ADD39797"/>
        <property type="gene ID" value="Snas_0075"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0075"/>
    <dbReference type="eggNOG" id="COG1252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021377_8_1_11"/>
    <dbReference type="OMA" id="FVGQCIS"/>
    <dbReference type="OrthoDB" id="403436at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="352" mass="37091" checksum="16AD536DB198863E" modified="2010-04-20" version="1">MKVVVVGAGYAGMMAANKLARKARNAEITVINPRPQFVERVRLHQRIAATTRAARPFSAMLRKGIRSRVGTVDKIGDGTVVLDDGARFDFDHAILAVGSTVRPMPGTVPVGSWDGAEAARRSLAALGEGATVTVIGAGPTGIETASEIASTRPELRVRLIGAAIAHSYSLGARERVLTELERMNVDLVEDSVTEVTDGVVRLESGDRFRSDLSLWAVISGVPQLASRSGLAVNEDGQVIVDAYLRSVSDDRIFAVGDCAAVPGARFSCQCAIPQGGYVGGACARLLRGRELEPFVMRFRGRGVSLGRRDAVVQFTDADDNPKESFAAGATGVALKELATRGAKFGAGTGWGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0K6</accession>
    <name>D3Q0K6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Periplasmic solute binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2047</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial solute-binding protein 9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017313.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2047"/>
    <dbReference type="EnsemblBacteria" id="ADD41742">
        <property type="protein sequence ID" value="ADD41742"/>
        <property type="gene ID" value="Snas_2047"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2047"/>
    <dbReference type="eggNOG" id="COG0803">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016838_1_0_11"/>
    <dbReference type="OMA" id="FHEAFDY"/>
    <dbReference type="OrthoDB" id="1703187at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006129">
        <property type="entry name" value="AdhesinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00691">
        <property type="entry name" value="ADHESINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048529" evidence="5">
        <location>
            <begin position="31"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="104"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="116"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="311" mass="33185" checksum="F5B3989E820F8DAD" modified="2010-04-20" version="1">MRKPLPRLAVLSVATALTTATLSACGSAGAQGSGVNVVASFYPLQFVSEQVGGEHVTVTNLTAAGAEPHDLELKPRQVADITDAQLVVFLKGFQPAVDDAVKEQAPDTSLDVAKTTELTKPEEGHEEHAEEGDHEHDHGDLDPHVWLDPTKLAEIADGVADRLAKADPDHAEDFKANAKSLGEKLTDLDSEYDDGLAKCDSRDLVTSHAAFGYLAARYDLHQVAMSGLTPESEPGSGAMKQIMDYVEEHGVTTIYYETLVSPDVAETIADKTGAKTAVLDPIEGLQKGSEDDYFSIMESNLSALREGLGCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0X4</accession>
    <name>D3Q0X4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycerone kinase</fullName>
            <ecNumber evidence="7">2.7.1.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4072</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.29" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019295.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4072"/>
    <dbReference type="EnsemblBacteria" id="ADD43724">
        <property type="protein sequence ID" value="ADD43724"/>
        <property type="gene ID" value="Snas_4072"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4072"/>
    <dbReference type="eggNOG" id="COG2376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017054_6_1_11"/>
    <dbReference type="OMA" id="TALNMNG"/>
    <dbReference type="OrthoDB" id="857242at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="SSF101473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="6">
        <location>
            <begin position="7"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="DhaL" evidence="5">
        <location>
            <begin position="411"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="619" mass="61856" checksum="9F802E63E29334A0" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Z6</accession>
    <name>D3Q0Z6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019317.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4095"/>
    <dbReference type="EnsemblBacteria" id="ADD43746">
        <property type="protein sequence ID" value="ADD43746"/>
        <property type="gene ID" value="Snas_4095"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4095"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097480_0_0_11"/>
    <dbReference type="OMA" id="PRQRVNY"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="196" mass="21804" checksum="EE8C2B09E14079F3" modified="2010-04-20" version="1">MTSEVDVVGDTGRVRGTFSPLRRRILEELAEPASATGLAERLGETRQRVNYHLRELEKGGLVELVEQRQRRGRIERFVRATAKAVVVAPEVIGKLDAVGEDRFAVDTLLAAAASTVNDVAAMREAAETAGKRLVTFTVEAEIGFGQPSDIERFATRLADRVAELVEEFDDPQSQRRYRLRLGAYPKRQVHDKETAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1J0</accession>
    <name>D3Q1J0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, CdaR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0117"/>
    <dbReference type="EnsemblBacteria" id="ADD39838">
        <property type="protein sequence ID" value="ADD39838"/>
        <property type="gene ID" value="Snas_0117"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0117"/>
    <dbReference type="eggNOG" id="COG3835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053843_0_0_11"/>
    <dbReference type="OMA" id="LEVHIGH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_30" evidence="1">
        <location>
            <begin position="349"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="411" mass="45316" checksum="4417D7CFF2E4F470" modified="2010-04-20" version="1">MNTHKEEPLRLGGQAVDDWLARRYERLAAELVDGFAATIPIYGRFPPDLRRDILWITRHNLDMFIGMLRQRQAPSAEDLAPLAESASRRAEEGVPLADVLTAYHQGIRVTWTQCASLATPDDHDDLVSVSTLVFEYQQIVTSVVATAYAEERQNILGHEREARRALVTALLDGQPAEELAERAGVHLAPGYLVLCLSFGSAEDSDGRRAAISDRRRVRAVASVLEVWPHGQVLTILDPHGGTALLPIKATEPGRTDAISPAERASLRESLAALDFPVLAAAHLSTIERVPVVHTTTREVVDLVERLDYPPGIYQLADVLLEYQFTRPGPGADVLAELLAPLERGTELETTLETYLRHDLSRNATAAALNVHPNTLDYRLNRIARLTGLNPSRQSDLHKLTAALIARRHTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1N8</accession>
    <name>D3Q1N8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0166</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015457.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0166"/>
    <dbReference type="EnsemblBacteria" id="ADD39886">
        <property type="protein sequence ID" value="ADD39886"/>
        <property type="gene ID" value="Snas_0166"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0166"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_1_11"/>
    <dbReference type="OMA" id="PSMVICE"/>
    <dbReference type="OrthoDB" id="816674at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD39886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="401" mass="45181" checksum="910757B49B6BEBC0" modified="2010-04-20" version="1">MSTVEVPRGVPLDRPNPFDPSPQLTRLRETRPISRMIFFPDEHEGWLITGHEQVKKVLADTRFSSSSTFQRSPVDSPFLPKQLKEFPVEPGMFIRMDPPDHTRLRRKLTGVFTVKRMKVLEARVAEIVNQHLDELAASPKPADLVEKFALPVPSMVICELLGVPYEERAEFQTRSHKMLSFSTQPEERMASIKEIQEYILGLAKQKRAEPTDDLLSDLTQDDDLEPAEMGGIGFLLLVAGHETTANMLGLGTFALLEHPEQLEILRDDPELMPKAVEELLRYLSIIHLGARRIAAEDIEFEGHLIKKGDSVSISVAGANRDPNKFDDPDTLDVRRTATGHVSFGHGVHQCLGQQLARIEMRIGFEALLRRFPGLRLAVDPSEVPLRTDMAIYGVHKLPVTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1Q1</accession>
    <name>D3Q1Q1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0179</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015470.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0179"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD39899">
        <property type="protein sequence ID" value="ADD39899"/>
        <property type="gene ID" value="Snas_0179"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0179"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_0_0_11"/>
    <dbReference type="OMA" id="MEAEWVK"/>
    <dbReference type="OrthoDB" id="635734at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="13"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="202"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD39899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="390" mass="43567" checksum="ED90784C421CCC3D" modified="2010-04-20" version="1">MKVTFLVHSLDRVGGITRATLTTASALAARGHGVRIAAIFRLSSRPRFDVDPRVEVVTLVDEVDGRRRSTRDSALRKRPSRIHPRGDTFYEHAYTELVDARLTEFLNDCEADVVVGTTPGLNVCLAALAPRGAITVAQEHMFYEHHEPSLRAELSRAYERMDAVVTLTQRDAARHRRELPHLASRVTRIPNSVPAPPRRARRPDNRVIVAAGRLEPAKNFAMLIDAFAIVHRHHPEWRLRVVGDGSQLDGLRAQIQRLGLSHRVSLPGMITPMDREWAAGGIAALSSDFESFGLTVIEAMHFGLPVVSTHCRYGPPEIITDGEDGLLCPVGDAERFGAALCRLIEDRALWRRCSRTARRTAGRYVPEEVVADYEKLFNRQLEHRDLSTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1R5</accession>
    <name>D3Q1R5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent carboxylate-amine ligase domain protein ATP-grasp</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015484.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0194"/>
    <dbReference type="EnsemblBacteria" id="ADD39913">
        <property type="protein sequence ID" value="ADD39913"/>
        <property type="gene ID" value="Snas_0194"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0194"/>
    <dbReference type="eggNOG" id="COG0026">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029016_6_0_11"/>
    <dbReference type="OMA" id="PWGDYVS"/>
    <dbReference type="OrthoDB" id="1677960at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="125"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="419" mass="44424" checksum="5CAA8CD0FD5E9167" modified="2010-04-20" version="1">MPNPNDRNGQKSLPTLVVVYAFGSASATQIVAAARGLCDIVLLADRSEPYVAEQFPLMLELASVIDATDRDEAEVLGEVTALAPSGVTTFADDKVELAARLARACGVVGHSEDTVEVVTDKLCQRRRLTEAGVEATRFAAIAGPGDVAAAAAEVGFPAVLKPRRGNGARNTRLVESEADCELAVTEVHGEETRGLLLEEALTGIGIRDEVHADYVSVESLSQDGGITTLCVTGRFPMAPPMRETGMIVPAALPDAEAERVVALERAILRALGVRDGLSHTEFKLTADGPRLIEVNARLGGPIGHLTKLALGIDVVRMGLLVALGQRVEVPPPSWRGVAFNRAVPPPLGVSEVVSVKPLAELRGLPGVVFCNQRVRPGDRVDSRRGERDMLATVVGLTESHEELLAINAAAERAAERMCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1X8</accession>
    <name>D3Q1X8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017416.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2151"/>
    <dbReference type="EnsemblBacteria" id="ADD41845">
        <property type="protein sequence ID" value="ADD41845"/>
        <property type="gene ID" value="Snas_2151"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2151"/>
    <dbReference type="eggNOG" id="COG0666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097136_0_0_11"/>
    <dbReference type="OMA" id="WHIGWWW"/>
    <dbReference type="OrthoDB" id="1920669at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="12"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="176" mass="19767" checksum="0795C17013FF0962" modified="2010-04-20" version="1">MPETVIPVLRWQFDLTWALFEIHLEPLSDADCLWEPADRCWTVRKGDDGVWRADFSETEPEPAPATTAGWLTWHIGWWWSSALRAVAGEAPYAPGEVAWPGNAAATVDWLRSLKAEWTKYLDGLTEADLGAPAPFPWPDGEHTVARLLAWLNAELMKNVAEIGHLRLQRAALGQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2J8</accession>
    <name>D3Q2J8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4282</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019502.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4282"/>
    <dbReference type="EnsemblBacteria" id="ADD43931">
        <property type="protein sequence ID" value="ADD43931"/>
        <property type="gene ID" value="Snas_4282"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4282"/>
    <dbReference type="eggNOG" id="ENOG5033TSK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055999_0_0_11"/>
    <dbReference type="OMA" id="YWQNGEN"/>
    <dbReference type="OrthoDB" id="1269500at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="33412" checksum="584B478A67804B18" modified="2010-04-20" version="1">MRSPFSSALRAAITSSGHSLENLSEQLRARGTPAGVSTLSSWQSGVNHPERRASLAALEGIEELLGLEPQALLALIPERKPRGRWRPPSATTLPHQRMWRSPRAVERVLAKLDAVPEDLYVPARVSRSVKIYLDSEGHERKSHHRLLVRGETGRADRLISLLRTDSLPQPPSVYDTVGCRAGRMRADVPGLLSAFELTFDEPLLPGELRVVEFGIHYPPGQNERHYDLRIPPGVRDLALQVEFDPARLPSRCRGFYQAAQERPERVLSESVPPQPLSRFQCVVLDPQPGIYGVRWDWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q315</accession>
    <name>D3Q315_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LPXTG-motif cell wall anchor domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0267</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015556.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0267"/>
    <dbReference type="EnsemblBacteria" id="ADD39985">
        <property type="protein sequence ID" value="ADD39985"/>
        <property type="gene ID" value="Snas_0267"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0267"/>
    <dbReference type="HOGENOM" id="CLU_775920_0_0_11"/>
    <dbReference type="OrthoDB" id="1598574at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013552">
        <property type="entry name" value="Thioester_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08341">
        <property type="entry name" value="TED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049490" evidence="2">
        <location>
            <begin position="29"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="TED" evidence="3">
        <location>
            <begin position="88"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD39985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="357" mass="37449" checksum="6FD8412B52C8B423" modified="2010-04-20" version="1">MKKSWIRAGVATAAVGTLGIATAGPAMAEDSEKYNYAGLFGAGDGYTLNTPDGSKLVANTTGIYPEEDEAGEARTYRLDTTPVSEDPEIVYDKHPWADTSIGNLGRVKWIVDNSFPTIDAATVADKAGADLTGVADPDKAAYTATQAAIWVLTSDLKLNPDDPTGENDAVDAAVLDITHYLINENERIAEPSDAFTVEGKAKWDGKRLGPFHFDGVDDEGWVMAHKVDSGHEAGKVVDEDGKKLTHLEPGQKFYVDPNKGIKKLVIGGIATDSPKAGTLMLPRYDKSQPTLILAEDAGYGVTTSRTVTVGGGSGSGGDDILPVTGMSLTGVMGIGAALLVGGALTLVLLRRRATAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q360</accession>
    <name>D3Q360_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015601.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40030">
        <property type="protein sequence ID" value="ADD40030"/>
        <property type="gene ID" value="Snas_0312"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0312"/>
    <dbReference type="HOGENOM" id="CLU_1401712_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001322">
        <property type="entry name" value="Lamin_tail_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036415">
        <property type="entry name" value="Lamin_tail_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00932">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74853">
        <property type="entry name" value="SSF74853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51841">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048201" description="LTD domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="LTD" evidence="2">
        <location>
            <begin position="7"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="194" mass="20331" checksum="7E97DC9B34BD712B" modified="2010-04-20" version="1">MPIPTIALTTVAISALGVLCAQPAAAMTTGNPVISELAPSGPGGSRDEYLELHNDGDNPVSIGGWRLYACDSASSPSLMTTFPAGTILAARGELGQYLLLAGDEYLGRSEHPGPQSPDIWYSFDTSASDGWMLTDRYNRRVDGIGTGTGEGCDDNPLVPRCRWGDAESATRDFRARADADGYVCGPASPTNSMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q362</accession>
    <name>D3Q362_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0314</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0314"/>
    <dbReference type="MEROPS" id="S08.069"/>
    <dbReference type="EnsemblBacteria" id="ADD40032">
        <property type="protein sequence ID" value="ADD40032"/>
        <property type="gene ID" value="Snas_0314"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0314"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007528_0_0_11"/>
    <dbReference type="OMA" id="SWATENT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048617" evidence="6">
        <location>
            <begin position="20"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="221"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1172" mass="123453" checksum="92BBB30188F41ADB" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3P4</accession>
    <name>D3Q3P4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4314"/>
    <dbReference type="EnsemblBacteria" id="ADD43961">
        <property type="protein sequence ID" value="ADD43961"/>
        <property type="gene ID" value="Snas_4314"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4314"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1894909_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="64"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="132" mass="14473" checksum="862E8D6D6F5312AF" modified="2010-04-20" version="1">MSTIVYPPTRGLSAWEAACRSAAIIAREAARDRRRELLTHHGRVLLNALAAAGIDLEPKPPVVVRPPGCRLTERELTVVIGMSNGKSNARIGRELHISEDTVKTYARRLFRKLGVGDRTQAVAVALRTGLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3S9</accession>
    <name>D3Q3S9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019567.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4349"/>
    <dbReference type="EnsemblBacteria" id="ADD43996">
        <property type="protein sequence ID" value="ADD43996"/>
        <property type="gene ID" value="Snas_4349"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4349"/>
    <dbReference type="HOGENOM" id="CLU_2939557_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="60" mass="6145" checksum="A9D16A4C86B62288" modified="2010-04-20" version="1">MSGQQFGFVAGFAFVALWAVAGIGWALGALVLGAVGFGIGRVLDGKVDIGAFADRFTPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3U1</accession>
    <name>D3Q3U1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ThiamineS protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019579.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4361"/>
    <dbReference type="EnsemblBacteria" id="ADD44008">
        <property type="protein sequence ID" value="ADD44008"/>
        <property type="gene ID" value="Snas_4361"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4361"/>
    <dbReference type="eggNOG" id="COG1977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114601_1_0_11"/>
    <dbReference type="OMA" id="RRHINVF"/>
    <dbReference type="OrthoDB" id="1995573at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="94" mass="10076" checksum="E0698A980D60543D" modified="2010-04-20" version="1">MAVTVYIPGALRNEAEGAKSLDVEVDANATLGAVLDTVASRHPRLGRRVRDERGQVRRYVNVFIGDDECRTLSGVDTKVPDGTEVRILPSVAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Y7</accession>
    <name>D3Q3Y7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GH18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4408</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019625.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4408"/>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44054">
        <property type="protein sequence ID" value="ADD44054"/>
        <property type="gene ID" value="Snas_4408"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4408"/>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019399_0_1_11"/>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048218" description="GH18 domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="2">
        <location>
            <begin position="69"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="338" mass="36337" checksum="93FBB6B2EC064422" modified="2010-04-20" version="1">MKRRTRLVAFGAAAVLAVGGGTGYAFANETEGSSGSGTSTSPDLSAAEMAAAPYLFEGWGDPPDVKTVMDATGVKAFTMAFILSDGTCNPSWDSQRPLEGGVDQKVIEEVRANGGDVMPSIGGWQGDKLGPRCGSPEELAGAYQKVIDAYGLKAIDVDIENTDEFENHEVQERILSALKIVKEKNPDIKTIVTFGTGKTGPNEHGVHLIEKSKELQANIDVFTIMPFDFGSSDIYTDTIAASEGLRDQLKKTYGWDDAEAYAHMGISGMNGMSDQSEETSPDTWTKIRDWAKQNSLARFTFWALNRDRPCPGGGTTSNCSGIDQKEWEFTSITAGFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q458</accession>
    <name>D3Q458_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021514.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6325"/>
    <dbReference type="EnsemblBacteria" id="ADD45943">
        <property type="protein sequence ID" value="ADD45943"/>
        <property type="gene ID" value="Snas_6325"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6325"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_449709_0_0_11"/>
    <dbReference type="OrthoDB" id="1317398at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="607" mass="64168" checksum="0734389CE105B79A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q472</accession>
    <name>D3Q472_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021528.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6340"/>
    <dbReference type="EnsemblBacteria" id="ADD45957">
        <property type="protein sequence ID" value="ADD45957"/>
        <property type="gene ID" value="Snas_6340"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6340"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_350510_0_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="753"/>
            <end position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="772" mass="84200" checksum="8A5BA9D8A8708764" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q495</accession>
    <name>D3Q495_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl-CoA hydratase 2</fullName>
            <ecNumber evidence="1">4.2.1.119</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Enoyl-CoA hydratase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_6364</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26526"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57319"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="EC" id="4.2.1.119"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.1.119" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021551.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6364"/>
    <dbReference type="EnsemblBacteria" id="ADD45980">
        <property type="protein sequence ID" value="ADD45980"/>
        <property type="gene ID" value="Snas_6364"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6364"/>
    <dbReference type="eggNOG" id="COG2030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094876_4_1_11"/>
    <dbReference type="OMA" id="MWTMGAA"/>
    <dbReference type="OrthoDB" id="1924578at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005835">
        <property type="term" value="C:fatty acid synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003965">
        <property type="entry name" value="Fatty_acid_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01483">
        <property type="entry name" value="FASYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC-like" evidence="5">
        <location>
            <begin position="8"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="131" mass="13289" checksum="623F10DA4325DD50" modified="2010-04-20" version="1">MNPGDELFSVEYAIHRADLAAYAAASGDNNPIHLDDTAAKAAGLPGVIAHGMYTMGLAARAVADWAGGPAKVAALTARFAKPVPVPADSPATVTVSGAVRKVLDDGAIEVNLTVQCDGTKVLAPARATVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4I0</accession>
    <name>D3Q4I0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0423</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015711.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0423"/>
    <dbReference type="EnsemblBacteria" id="ADD40140">
        <property type="protein sequence ID" value="ADD40140"/>
        <property type="gene ID" value="Snas_0423"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0423"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_81_0_11"/>
    <dbReference type="OMA" id="DWALVCT"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032783">
        <property type="entry name" value="AraC_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12852">
        <property type="entry name" value="Cupin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="210"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="33415" checksum="A0B71612319AD6EC" modified="2010-04-20" version="1">MDPLSDMLGGIRAEGACVNQVSLEPPWAIRFAEGGALTLLTAVRGEGVLVLADGTEHKLNEGSTALVRGDEPFHLADSAAAMDGPIKVLSGNGYETVCELSLDESDATTAVIVGTYRTTCTRQERLLRTLPSALVVDEDTTDATKPEVATLGGWLDAVTDALRRRRGPGGQALIDRLLDWGLVCTLACWFEHQGADAPAWYRGAQDPVAGPALEAIHNRPQHLWTVGALAAEAKVSRAHLAKRFAEVMGQPPLKYLTEWRMYTAEDLLSDSDMSVAEVARAVGYADPFAFSTAFKRHRGTSPRQYRSAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Q7</accession>
    <name>D3Q4Q7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Small GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2404</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017658.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2404"/>
    <dbReference type="EnsemblBacteria" id="ADD42087">
        <property type="protein sequence ID" value="ADD42087"/>
        <property type="gene ID" value="Snas_2404"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2404"/>
    <dbReference type="eggNOG" id="COG0480">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002794_4_2_11"/>
    <dbReference type="OMA" id="DRGHEDH"/>
    <dbReference type="OrthoDB" id="88967at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="21"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="718" mass="76462" checksum="53A86A372AC8CA41" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4W4</accession>
    <name>D3Q4W4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2461"/>
    <dbReference type="EnsemblBacteria" id="ADD42144">
        <property type="protein sequence ID" value="ADD42144"/>
        <property type="gene ID" value="Snas_2461"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2461"/>
    <dbReference type="eggNOG" id="COG0716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105338_0_1_11"/>
    <dbReference type="OMA" id="CRGWDTN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026816">
        <property type="entry name" value="Flavodoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12724">
        <property type="entry name" value="Flavodoxin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="1">
        <location>
            <begin position="12"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="161" mass="17793" checksum="7A1E4A31456D8EA9" modified="2010-04-20" version="1">MRKRKGQPMNATIVCTSVSHGNTMRIAETMGQVLRARVVDPEQVDPADLSGSDLVGFGSGIFNMNFHPRLRDFIESLPTVDGQAAFVFATSGLPEPPFKRYTRDLARALERKGYDVVDTFICRGYDTWFPFRIVGGVAKGRPTAAELDAARQFAERLRPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5A2</accession>
    <name>D3Q5A2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MDMPI_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019722.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4506"/>
    <dbReference type="EnsemblBacteria" id="ADD44151">
        <property type="protein sequence ID" value="ADD44151"/>
        <property type="gene ID" value="Snas_4506"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4506"/>
    <dbReference type="eggNOG" id="ENOG50314EV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094601_0_0_11"/>
    <dbReference type="OMA" id="EIVHGED"/>
    <dbReference type="OrthoDB" id="2054078at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="1">
        <location>
            <begin position="20"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="219" mass="23894" checksum="57858A7258D8D179" modified="2010-04-20" version="1">MTATHTPTITGKKVAMLADLAAERLDLADYLETLDDSQWRTTTLCPAWNVHQMLAHLTLSNRTKVLPTLWHVVKARGDFDRVEAELADTRAATYSRAELLAQLRETAAADRRLALAGKLDPLVDILVHGQDITRPLGHHRPMPVHRVVPALEHVWGSVFYGSRKRFKGLRFVATDADWSAGEGPEVRGPVGDILLAATGRAAGLDALSGPGRTEAAGRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q692</accession>
    <name>D3Q692_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2587"/>
    <dbReference type="EnsemblBacteria" id="ADD42267">
        <property type="protein sequence ID" value="ADD42267"/>
        <property type="gene ID" value="Snas_2587"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2587"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_0_0_11"/>
    <dbReference type="OMA" id="QECSIAR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="176" mass="19743" checksum="813167585CAB6384" modified="2010-04-20" version="1">MMDVMALGKGYGNQDCSMARGLELVGERWTLLIVRDAFYGVRRFSDFLAHLEIPRAVLSERLQYLTDMGVLSKDSHEGSTRAEYALTDTGLALWPVLASLSQWSNEYLHSEAGPYLIYEHDPCGTELADRLNCPTCGERVRLADIATSPGPAANRTRDDVVSRSLLKRRRLLDPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q693</accession>
    <name>D3Q693_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2589</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2589"/>
    <dbReference type="EnsemblBacteria" id="ADD42268">
        <property type="protein sequence ID" value="ADD42268"/>
        <property type="gene ID" value="Snas_2589"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2589"/>
    <dbReference type="eggNOG" id="COG0815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040924_0_0_11"/>
    <dbReference type="OMA" id="WALAICK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045378">
        <property type="entry name" value="LNT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20154">
        <property type="entry name" value="LNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="449"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="LNT_N" evidence="3">
        <location>
            <begin position="19"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="277"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="472" mass="50848" checksum="2029376018C41E6D" modified="2010-04-20" version="1">MNSSRLNLLLTIAAVVATAALYAFGFALDPLPWLVWIAPLPMLLLAPRLGVWSVVTASAVAWLLGGLRLYWYFYDAIQFPVPALLAIAVSTSVGFAACVLLFRALVLRRHFALAAVGFASAWVAFEYLMSLLNREAAGNWYSIAYTQADLLPVLQTASLAGTAGIAFLLMVVPAAVAVCFAPGATVSAQAWVGGGVAVLLAAALGYGFARPQPSDDATRTAALAYPRDDGSAKVGTPEHQRVFEQYRDGVRDLAAEDVVTVVLPEKLVIVDKKHKDDYFAQWGKVARGAKINVVLGMELEEQDHVSNAAVWFPANGSEPTIFRKHHMIPGLESYLKPSDELTFVPGPDSWALAICKDLDFVDFVARYREAGATIIFAPALDFDTDGWWHSRVAVTRGVEQGVSLVRAGQKGLVTVSDQYGRVLAEDAEVAVAEVGTNGASTVYSRFGDWLVWVSLGMTALALVFAVRRKAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6M7</accession>
    <name>D3Q6M7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PhoH family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4627</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019841.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4627"/>
    <dbReference type="EnsemblBacteria" id="ADD44270">
        <property type="protein sequence ID" value="ADD44270"/>
        <property type="gene ID" value="Snas_4627"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4627"/>
    <dbReference type="eggNOG" id="COG1702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051654_2_1_11"/>
    <dbReference type="OMA" id="PAQMKMV"/>
    <dbReference type="OrthoDB" id="445854at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoH" evidence="3">
        <location>
            <begin position="119"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="344" mass="37432" checksum="AF9C6D33CC0DF8FD" modified="2010-04-20" version="1">MSEGPTSGGASRPQAKITVGDPSTMVSLLGSADEHLRFIERAIKADVHVRGDTITLTGAPKDIAEAERLFYELIAVIERGEAVTVDVVRRISGMLAEGATESPSDVMTQNIVSRRGRNIRPKTVGQKRYVDAIDDHTIVFGIGPAGTGKTYLAMAKAVQALQAKQINRIILTRPAVEAGERLGYLPGTLFEKIDPYLRPLYDALHDMIDPDSIPKLMESGTIEVAPLAYMRGRTLNDAFIILDEAQNTTAEQMKMFLTRLGFGSKIVVTGDVTQVDLPGGARSGLKIVRDILEGVDDLHFASLGSADVVRHRLVADIVDAYGKWDAEQRDSGAPDSTRKPNRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6N7</accession>
    <name>D3Q6N7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminopeptidase N</fullName>
            <ecNumber evidence="3">3.4.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Snas_4637</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4637"/>
    <dbReference type="EnsemblBacteria" id="ADD44280">
        <property type="protein sequence ID" value="ADD44280"/>
        <property type="gene ID" value="Snas_4637"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4637"/>
    <dbReference type="eggNOG" id="COG0308">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014298_2_0_11"/>
    <dbReference type="OMA" id="LWTMQEP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034015">
        <property type="entry name" value="M1_LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726">
        <property type="entry name" value="PTHR45726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M1_N" evidence="14">
        <location>
            <begin position="69"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="13">
        <location>
            <begin position="279"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD44280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="488" mass="53199" checksum="F7E1C98EF2B5478A" modified="2010-04-20" version="1">MNPRLGVIAVAGVTTAVLVAGCGQTGKLESESSDGPPEAAKEDLEAGKSEPVTDPMYPDYGHENIDVLHYGMELDYSPEKKTLSGLVRLTIRPVEDASELALDFSDAMEISNLTVDGKKTDFDLNEWDLTVDTGLKKDRNVEVEVTYKGTPELVDAPAERGDMAEGLGASVGQNGELWAFQEPHGALTWYPVNDHPSDEAMYDFEVTVPEGYAGVASGTFEGKKGNTYSWSSSDPVASYLTTIAVDKYEMVEMEGPGDLPVTAWIPPQYAEWEASLKKMPEMIEYLEKLYGPYPFDSAGLVLVGGESGMETQQMITLSGAVGMGGPEASESVVVHELAHQWFGDTVTPLDWTGLWINEGPATYAEQMWLVDQGMQTAKDVEKAFEAQDQDLRTQHGPPGDPDPNAFASSNSYVCPALMLIKLGDQIGGRDKVDELLGAWVAAHENKSVTREDFVGFANEHTGKDLTKFFDSWLDSAKTPKDKKDKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Z0</accession>
    <name>D3Q6Z0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015960.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0676"/>
    <dbReference type="EnsemblBacteria" id="ADD40389">
        <property type="protein sequence ID" value="ADD40389"/>
        <property type="gene ID" value="Snas_0676"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0676"/>
    <dbReference type="HOGENOM" id="CLU_1991314_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="125" mass="13270" checksum="87282C25BF752093" modified="2010-04-20" version="1">MTEPDPKVKAFNQNVNDGVAVDTDQIPGEAKRMGGVAGHIRTHLHTGPKTVTLDGGHTAKLASAAALKTTVSQWVKWGNERAGDVTATGDATRTNGEAWVDTDKNGRQDFRPDLVVPKPTTLPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q709</accession>
    <name>D3Q709_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Spermidine synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015979.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0695"/>
    <dbReference type="EnsemblBacteria" id="ADD40408">
        <property type="protein sequence ID" value="ADD40408"/>
        <property type="gene ID" value="Snas_0695"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0695"/>
    <dbReference type="eggNOG" id="COG0421">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068637_2_0_11"/>
    <dbReference type="OMA" id="YIQATRP"/>
    <dbReference type="OrthoDB" id="1613081at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="271" mass="29027" checksum="1BF028AF310D9420" modified="2010-04-20" version="1">MGETEQPKVLASTQVATGPARIIADPHRELGRFLEVGGFAQSYVKLDEPTFLWADYSMWVATVIDTVGAKDAPLRVLHLGGGGMTLPRYVHGVRPNAIQTVVEMDGPLVEFVREHLPLPEGSRVDIVVGDAVEVLAGLPDAEFDIVISDVYAANQTPRGTACLEYAQQLSRVLRPEGTCVVNVLDVEGLVMTRLHAAALNTVFEDLCVVSAHTPNVKRFLNIVMAATNSASGLPYPAISDAAVHHDTEVALIHGDDLAPVIAGVEPLRAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q750</accession>
    <name>D3Q750_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_2644</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2644"/>
    <dbReference type="EnsemblBacteria" id="ADD42321">
        <property type="protein sequence ID" value="ADD42321"/>
        <property type="gene ID" value="Snas_2644"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2644"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012341_2_0_11"/>
    <dbReference type="OMA" id="GGSVWFL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038766">
        <property type="entry name" value="Membrane_comp_ABC_pdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30287">
        <property type="entry name" value="PTHR30287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="723"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="768"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="812"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="39"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="296"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="752"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="852" mass="87621" checksum="5B2980E8844071D2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q799</accession>
    <name>D3Q799_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock protein 70</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2693</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2693"/>
    <dbReference type="EnsemblBacteria" id="ADD42370">
        <property type="protein sequence ID" value="ADD42370"/>
        <property type="gene ID" value="Snas_2693"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2693"/>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_457015_0_0_11"/>
    <dbReference type="OMA" id="NCAPITE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="428"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="447"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="597" mass="63374" checksum="8685AF264C2939B8" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7I8</accession>
    <name>D3Q7I8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4687</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019901.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4687"/>
    <dbReference type="EnsemblBacteria" id="ADD44330">
        <property type="protein sequence ID" value="ADD44330"/>
        <property type="gene ID" value="Snas_4687"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4687"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2525941_0_0_11"/>
    <dbReference type="OrthoDB" id="1871698at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="84" mass="9008" checksum="A24A748AA7934245" modified="2010-04-20" version="1">MHVMAVSSVTGEKGFWGALKKAHGRLPKQARWAFAVASTDGNRAVNIIVHDSVEGVRDWFEECAGSFATTEFTEADAANAVGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7K1</accession>
    <name>D3Q7K1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gas vesicle protein GVPa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019914.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4700"/>
    <dbReference type="EnsemblBacteria" id="ADD44343">
        <property type="protein sequence ID" value="ADD44343"/>
        <property type="gene ID" value="Snas_4700"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4700"/>
    <dbReference type="HOGENOM" id="CLU_184560_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031411">
        <property type="term" value="C:gas vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000638">
        <property type="entry name" value="Gas-vesicle_GvpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00741">
        <property type="entry name" value="Gas_vesicle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0304">Gas vesicle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0926">Vacuole</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="65" mass="6897" checksum="1DD973295C7FAFCB" modified="2010-04-20" version="1">MTTAVEPRWDSEQTVALVDLLDRVLAGGVVIAGDIRLSIAGIDLVQVSLRALITSLGDPELTVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7K9</accession>
    <name>D3Q7K9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019922.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4708"/>
    <dbReference type="EnsemblBacteria" id="ADD44351">
        <property type="protein sequence ID" value="ADD44351"/>
        <property type="gene ID" value="Snas_4708"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4708"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_11"/>
    <dbReference type="OMA" id="ESGWINT"/>
    <dbReference type="OrthoDB" id="1209997at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="279" mass="28911" checksum="3A8C8BBB55990E19" modified="2010-04-20" version="1">MDMGLSGRPALITGSSGGIGAEIARSLATEGCPVLVHGRGAESARRVAERLRASGATAEVVLGDVTDAADAERVAEAARGFGVRILVNNTGPFSEHSWETSTPDDWRDALDSNVVATVRLTQALLPVLRSDGWGRVITIGSRANTTPLPNMVEYSAAKAAVVNLTTSLAQHLAGSGVTANCVSPGVILTDSARRMFETRAASESWPQRDWPDIEARVASEYAPNPSGRLGRAEDIAAAVTYLASPLADYVNGVELRVDGGITGTPLVTAGSASSSRTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7L3</accession>
    <name>D3Q7L3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AhpC-TSA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019926.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4712"/>
    <dbReference type="EnsemblBacteria" id="ADD44355">
        <property type="protein sequence ID" value="ADD44355"/>
        <property type="gene ID" value="Snas_4712"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4712"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084744_0_0_11"/>
    <dbReference type="OMA" id="ADFLIAP"/>
    <dbReference type="OrthoDB" id="892697at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AhpC-TSA" evidence="1">
        <location>
            <begin position="18"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="191" mass="21288" checksum="6BC6254A47B44B56" modified="2010-04-20" version="1">MSIPLAPDSTIRVRSFDTVAGGTVSVPDPKRVVHLQFRRFAGCPICHTHLRSIAKRHDEIRSAGIREVVFFHTGIDELYEYTDMLPFDVVADPDKRVYREFGVESARRAILSLGGLWAVLRTAIPTTVRILTGRQRPPSSKPEGGRLGLPADLLIAPDGRVLAAHYGEHMDDQWSVDELLRLAAEVTSPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7S1</accession>
    <name>D3Q7S1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019984.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4771"/>
    <dbReference type="EnsemblBacteria" id="ADD44413">
        <property type="protein sequence ID" value="ADD44413"/>
        <property type="gene ID" value="Snas_4771"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4771"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_49_0_11"/>
    <dbReference type="OMA" id="GIRWVSY"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="27"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="278" mass="29387" checksum="3216B94136680526" modified="2010-04-20" version="1">MVKEFDVTLADGRTLHGYDTGGEDRMPVVWHHGTPNVGAPPAPLFVESERLGIRWVSYDRPGYGTSTPRPGRDFASAAGDVAAIADALGIDRFAVMGHSSGGPHALACAALLPERVTGVVAASALAPFDAEGLDWFAGMADGAAASLRASAAGRAAKEKYEETAEFDEAMFIPADYEALNGQWSWFNEVVRAAAANGPSPLIDDDLANVGDWGFDPRDVTVSTLVMHGAKDRLIPSSHGVWLVEHLPNARLRLLPGDGHISVMNSATEGLEFLAALGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7T3</accession>
    <name>D3Q7T3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4784</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019996.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44425">
        <property type="protein sequence ID" value="ADD44425"/>
        <property type="gene ID" value="Snas_4784"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4784"/>
    <dbReference type="HOGENOM" id="CLU_943048_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049777" evidence="2">
        <location>
            <begin position="35"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="295" mass="31081" checksum="780D07E2F2F70095" modified="2010-04-20" version="1">MSRPSVRPKPKPLSARVLFWTGLVLVALPLPVMAVTESSANLLSGDLDDVAQAVGFCAPFVGYPMVVAGRFMARLARDGDAALPTRFERAPRLRWSAGFGRSFLNAAIVAIVGIAVMMLAWAGLTSLFTGETLSFDTQPLGAVGEGVMAFAISGLLTATAWMILGLFWYGGLVVGYSLWRLGSRNSNRGERSAAGMVVAAVLVVIGVTGVVVAGNAGLPADNTVLRGLMATVGALLLVVPLAYAISVGWRQGQRPWGFTGKPDEPGKIIAAVFRLFAALALLTWLVTALLRAWQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Y1</accession>
    <name>D3Q7Y1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_0774</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016057.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0774"/>
    <dbReference type="EnsemblBacteria" id="ADD40486">
        <property type="protein sequence ID" value="ADD40486"/>
        <property type="gene ID" value="Snas_0774"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0774"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002683">
        <property type="entry name" value="PsbP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01789">
        <property type="entry name" value="PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="SSF55724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="30"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="313"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD40486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="595" mass="62077" checksum="A5D6653A5AAA58FB" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q883</accession>
    <name>D3Q883_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phospholipid N-methyltransferase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2781</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2781"/>
    <dbReference type="EnsemblBacteria" id="ADD42457">
        <property type="protein sequence ID" value="ADD42457"/>
        <property type="gene ID" value="Snas_2781"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2781"/>
    <dbReference type="eggNOG" id="COG3963">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085338_2_1_11"/>
    <dbReference type="OMA" id="RIMTSEI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="228" mass="24748" checksum="38EAD0B77D5F621C" modified="2010-04-20" version="1">MTTSLPRHGGDAPPSAVPSNENEEIPPSQWHDRKLFFRHWLRAPGVTGAMLPSSRAMARTMGTVLEGYQSPTVAELGSGTGAVTAVIQQRLRGASPHLAIEIHEEFASRLQKLYPDVSVVNQSAADLEQILKEHQIDSLDVVISGLPFTAFTPQLQSDILDAVVGSLNEDGVFATHRYVGAGYFPAAQRFRALLESRFAEVTVSRPNFGNLPPARLLTARGPRKSPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8H9</accession>
    <name>D3Q8H9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018124.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2878"/>
    <dbReference type="EnsemblBacteria" id="ADD42553">
        <property type="protein sequence ID" value="ADD42553"/>
        <property type="gene ID" value="Snas_2878"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2878"/>
    <dbReference type="eggNOG" id="COG0662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103066_1_0_11"/>
    <dbReference type="OMA" id="DNHYVDS"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="45"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="161" mass="17351" checksum="DEF6559F3B3E997A" modified="2010-04-20" version="1">MSDYPKPVLVRAAEAETLQDGPTSLLTLLADSDTTGDAMTVNRATLSDGSPGAPPHFHTRAAEAFFIIDGAMRMLLGDTITTLHKGDFLVVPSMLPHAFAPVPGGSADALVVFSPGMARFDYYRLLERVFKGMSDISEIAASSGRYDNHYCDSPVWREALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8N6</accession>
    <name>D3Q8N6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyltransferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4837</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020049.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4837"/>
    <dbReference type="EnsemblBacteria" id="ADD44478">
        <property type="protein sequence ID" value="ADD44478"/>
        <property type="gene ID" value="Snas_4837"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4837"/>
    <dbReference type="eggNOG" id="COG3594">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047004_2_0_11"/>
    <dbReference type="OMA" id="ACFFAWV"/>
    <dbReference type="OrthoDB" id="1221455at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="3">
        <location>
            <begin position="42"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="382" mass="42645" checksum="B66B65586DCFFDFA" modified="2010-04-20" version="1">MSTEVLAHTGATTRSAAPAPSKPESPSGGTAKDPLFSNAKLALIVLVVVGHSWGPLFTDSDTVRAFYMTLYDFHMPAFILVCGYFSQSFSGRPHQMRRLVTGVAAPYFIFALLYGAMRYFTEDEFNPSLLTPYYLLWFLAALFVWRITAPIWKLVRYPLVVALVISIGASTMELPKELDLGRILQFLPFFVAGLLMKREHFEKLRNPVVRIAGPILSVGILAAAFFYGNDIHIDWIYYTAGATQLDVQWHTAIGLKLVMLAAATVLIATFFAWVPDKQLSFTRMGELTMYPFLLHGFFIKIAEDGYDLYDIPFVDTGAGAVVITLTALVLAFVLLSKPIRWMTSPLVEPKLNWILKPTPRPPSPRPRPQAREDKPTAETSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8P3</accession>
    <name>D3Q8P3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4844</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020056.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4844"/>
    <dbReference type="EnsemblBacteria" id="ADD44485">
        <property type="protein sequence ID" value="ADD44485"/>
        <property type="gene ID" value="Snas_4844"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4844"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_3_1_11"/>
    <dbReference type="OMA" id="YLAWQSW"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048316" evidence="6">
        <location>
            <begin position="26"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="22361" checksum="31A474D1A6709193" modified="2010-04-20" version="1">MTTAMFLSFLVFAFLLALSPGPDTAVVLKNSLTGGRRLGFGASVGITLGNVVHGTSAVFGVGLLLVQWRPVFEAIRWAGIAYLVYLGVQALRSAWRGGYLDGEAAGDGRARRRGAVARAGVQGFLSNITNPKAFAFYLSVLPQFMAGGDGSVGTLLGLAYTHAAVTLLWLLVLVAGLHLVRDWLRRRVVRRAMDAVTGTALLGFGVKLAADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8V4</accession>
    <name>D3Q8V4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">(Glutamate--ammonia-ligase) adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.42</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4905</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.42" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020117.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4905"/>
    <dbReference type="EnsemblBacteria" id="ADD44546">
        <property type="protein sequence ID" value="ADD44546"/>
        <property type="gene ID" value="Snas_4905"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4905"/>
    <dbReference type="eggNOG" id="COG1391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006233_1_0_11"/>
    <dbReference type="OMA" id="EFMVQYA"/>
    <dbReference type="OrthoDB" id="427701at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008882">
        <property type="term" value="F:[glutamate-ammonia-ligase] adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023057">
        <property type="entry name" value="GlnE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005190">
        <property type="entry name" value="GlnE_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013546">
        <property type="entry name" value="PII_UdlTrfase/GS_AdlTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30621">
        <property type="entry name" value="PTHR30621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08335">
        <property type="entry name" value="GlnD_UR_UTase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03710">
        <property type="entry name" value="GlnE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GlnE" evidence="4">
        <location>
            <begin position="152"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="GlnD_UR_UTase" evidence="5">
        <location>
            <begin position="344"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="GlnE" evidence="4">
        <location>
            <begin position="578"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="domain" description="GlnD_UR_UTase" evidence="5">
        <location>
            <begin position="825"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="58"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="973" mass="104719" checksum="EC65AD5A87408862" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8X5</accession>
    <name>D3Q8X5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
            <shortName evidence="5">AcCoA synthetase</shortName>
            <shortName evidence="5">Acs</shortName>
            <ecNumber evidence="5">6.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acetate--CoA ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Acyl-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">acsA</name>
        <name evidence="9" type="ordered locus">Snas_0873</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="5">Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0873"/>
    <dbReference type="EnsemblBacteria" id="ADD40584">
        <property type="protein sequence ID" value="ADD40584"/>
        <property type="gene ID" value="Snas_0873"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0873"/>
    <dbReference type="eggNOG" id="COG0365">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_3_6_11"/>
    <dbReference type="OMA" id="AIKASWP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01123">
        <property type="entry name" value="Ac_CoA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACAS_N" evidence="8">
        <location>
            <begin position="37"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="6">
        <location>
            <begin position="95"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="7">
        <location>
            <begin position="536"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="5">
        <location>
            <begin position="198"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="392"/>
            <end position="394"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="416"/>
            <end position="421"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="505"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="520"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="528"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="542"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="544"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="547"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine" evidence="5">
        <location>
            <position position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="655" mass="71721" checksum="55357614FB3AC0CF" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Z6</accession>
    <name>D3Q8Z6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Galactose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="13">2.7.7.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Snas_0894</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12 13">
            <text>alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:13989"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="2.7.7.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.12" evidence="13"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016176.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0894"/>
    <dbReference type="EnsemblBacteria" id="ADD40605">
        <property type="protein sequence ID" value="ADD40605"/>
        <property type="gene ID" value="Snas_0894"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0894"/>
    <dbReference type="eggNOG" id="COG1085">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029960_1_1_11"/>
    <dbReference type="OMA" id="HAIYYPP"/>
    <dbReference type="OrthoDB" id="1064872at2"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008108">
        <property type="term" value="F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033499">
        <property type="term" value="P:galactose catabolic process via UDP-galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001937">
        <property type="entry name" value="GalP_UDPtransf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019779">
        <property type="entry name" value="GalP_UDPtransf1_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005850">
        <property type="entry name" value="GalP_Utransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005849">
        <property type="entry name" value="GalP_Utransf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11943">
        <property type="entry name" value="PTHR11943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02744">
        <property type="entry name" value="GalP_UDP_tr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01087">
        <property type="entry name" value="GalP_UDP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000808">
        <property type="entry name" value="GalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00209">
        <property type="entry name" value="galT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00117">
        <property type="entry name" value="GAL_P_UDP_TRANSF_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 13" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="6 11 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GalP_UDP_transf" evidence="14">
        <location>
            <begin position="45"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="GalP_UDP_tr_C" evidence="15">
        <location>
            <begin position="215"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-UMP-histidine intermediate" evidence="10 12">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ADD40605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="359" mass="39965" checksum="2DDDFA441D7B2CD2" modified="2010-04-20" version="1">MTPSTTEPTLTRLADGRELFYYDEHPGSGRDSFADKRDLPPRSTAAQLRHDVLRDEWVAVAAARQTRPVLPATNRCPLCPSTDDNLTEIPAPSYDVAVFENRFPSFGGRTAADPHQPHPPAAGRCEVVCFTSDHGSSFAELSPTRARLVLDAQIDRTAKLSRRDDIEQVFCFENRGEEIGVTLHHPHGQIYGFPYVAPDLAKMLAVARRHRDNGGGNLFAETLAAERAEGTRIVATGEHWTAFVPVAARWPFEVHLYPHTRAADLTELPGGYRDSFAPVYLDVLRRFDALFDSPLPYISAWYQGPVRADRDLSYTHLRLFSIRRAPGKLKYLAGSESAMGAFVNDVPPEEAARMLREAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q932</accession>
    <name>D3Q932_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0930</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016212.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0930"/>
    <dbReference type="EnsemblBacteria" id="ADD40641">
        <property type="protein sequence ID" value="ADD40641"/>
        <property type="gene ID" value="Snas_0930"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0930"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_40_3_11"/>
    <dbReference type="OMA" id="TEVFWAA"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="194" mass="21578" checksum="48F503ADE70ACEB6" modified="2010-04-20" version="1">MSTQTRKERERAQRHQLIITTARELAEADGWDAVTTRKLSERIEYSQPVLYSHFKGKRAIMDAVILEGCAELAVLMREARTRARRPDTALTAVADAYMDFGREHPATFDAMFTLPSDLPFGPEAPQPLKDAFAELYAVFSPLAGSRDPMVFTEVGWSAIHGVAVLDRSGRLPPQDANKRLSILVKQLLAPEPGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9A2</accession>
    <name>D3Q9A2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_2909</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018155.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2909"/>
    <dbReference type="EnsemblBacteria" id="ADD42584">
        <property type="protein sequence ID" value="ADD42584"/>
        <property type="gene ID" value="Snas_2909"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2909"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_9_2_11"/>
    <dbReference type="OMA" id="DIMIHET"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="15"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="115"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="221"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="396" mass="43737" checksum="84BBCDE86A7F5C57" modified="2010-04-20" version="1">MSDTESIEPDLTARVATLLRDHDPATTDPQEFRGALFDAGLARVDFPPGLGGLGLPQRFQKLVDARLEAADAPMLLREHNGIGLGMAAPTIVAFGTDEQRRTLLRPIFTNEHVYCQLFSEPEAGSDLAAVATSARRDGDEWIVNGQKVWTSGAHNADMAILLARSDPDLPKHAGLTYFVCDMRDPGVEVRPLRQLTGEAEFNEVFLTDVRVPDSLRLGEIGQGWKVATTTLNNERVAIGSGAPREGGMIGRVAATWRDNPQWRHPGMHDRLMRLWVDAEAIRITGERLRQQLANGQPGPEGSGMKVLFARSAQEVSGFDLELRGEDGLRYDDWTMRRPDKVDYTGREPGYRYLRAKGNSIEGGTSEILLNVIAERVLGLAPEPRADKDIAWKDLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9R0</accession>
    <name>D3Q9R0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Diacylglycerol O-acyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Snas_4968</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycerol + an acyl-CoA = a triacyl-sn-glycerol + CoA</text>
            <dbReference type="Rhea" id="RHEA:10868"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:64615"/>
            <dbReference type="EC" id="2.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the long-chain O-acyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.20" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4968"/>
    <dbReference type="EnsemblBacteria" id="ADD44606">
        <property type="protein sequence ID" value="ADD44606"/>
        <property type="gene ID" value="Snas_4968"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4968"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024186_5_0_11"/>
    <dbReference type="OMA" id="RWAMLTK"/>
    <dbReference type="UniPathway" id="UPA00282"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045034">
        <property type="entry name" value="O-acyltransferase_WSD1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009721">
        <property type="entry name" value="O-acyltransferase_WSD1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004255">
        <property type="entry name" value="O-acyltransferase_WSD1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31650">
        <property type="entry name" value="PTHR31650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03007">
        <property type="entry name" value="WES_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06974">
        <property type="entry name" value="WS_DGAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="WES_acyltransf" evidence="11">
        <location>
            <begin position="47"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="WS_DGAT_C" evidence="12">
        <location>
            <begin position="277"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF06974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD44606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="417" mass="46419" checksum="27620DDD077C4593" modified="2010-04-20" version="1">MCDNVSRTGVFVNERAKPLRGIDQCLVTYEKRCGRSVGIGLLLRFDGEAPDLSQLVRHLAERFSTVPELRWLLGESRGRSVWYPDPRFSWDSRIAQYSGYRADGETGLRAAVGDIAAMRLDPATAPWRAWLLRGFAPGQWALMLHVHHALADGQSMMSLAHRAFGERSSLSRPSRSWITPRRLSRRESWAKLLRGGPRQAWNLVPRRFPTRNANGDHRVDWATFDSAQVRRIAAHHDATVNDVVLALTTRTLSTGDTTPYALIPVSTRSADDTHRLGNELTTMRVPLPKRHQDPVSALKAITAATTQAKHGRDIDVSRAGAEVLPSWVFASLFRHALTGGYVDIIVSNWGTTPALAFHDNPVRELVPIMFRPPGHATTIGFATHGNRTHVGVVSTSDTDRLRDHWHSALTSLHDSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAD6</accession>
    <name>D3QAD6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase M24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3048</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018290.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3048"/>
    <dbReference type="MEROPS" id="M24.033"/>
    <dbReference type="EnsemblBacteria" id="ADD42719">
        <property type="protein sequence ID" value="ADD42719"/>
        <property type="gene ID" value="Snas_3048"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3048"/>
    <dbReference type="eggNOG" id="COG0006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017266_1_0_11"/>
    <dbReference type="OMA" id="YRRWTLH"/>
    <dbReference type="OrthoDB" id="415910at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP_N" evidence="4">
        <location>
            <begin position="48"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="501" mass="55663" checksum="CCE1DE3FCB0B118A" modified="2010-04-20" version="1">MSETNAAAAEAAPKSGERSHDPKYPEKFLQFMRTGWGSSDLTGLVAVPQSVRHAQRRDALSQAFPGETLIIPTGAEKVRANDTFFRFRAGSDFAWLTGDYDPEGVLVLSPAAGGHDAVLYRRQRKSKESDEFFRSAQYGELWVGRRYSLDETATLLGIECRDLDELEALLPQFERDKARVLRGIDAVIDAAIAAEEAGRSEDGTPELTRDRELAAVLSELRLIKDEWELEQLQDAVDATVRGFEDVARVIPRDRAVRERLLEGVFAMRARLEGNGIGYDSIVGAGSHATTLHWITNDGATVPGELILMDMGIENNHLYTADVTRTLPVSGRFTDLQRQVYDLVYASQQAGMDAIKPGVDYKHIHQTCMRVLAEGLSDLGILPVSVDEAMADDSLVYRRWTLHGFGHMLGIDVHDCAAARTDHYWQGKLAEGHVLTVEPGLYFQTDDELVPEELRGIGVRIEDDVLVTADGHRNLSDGLPRTSTDVEEWFAARRDEEPRFPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAW3</accession>
    <name>D3QAW3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5124</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020330.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5124"/>
    <dbReference type="EnsemblBacteria" id="ADD44759">
        <property type="protein sequence ID" value="ADD44759"/>
        <property type="gene ID" value="Snas_5124"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5124"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="CEENSTE"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="11"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="232" mass="24249" checksum="6AB897130D1D9B25" modified="2010-04-20" version="1">MRNSDVDGVALEITELDYAIGNRRLFSGLELSVAIGETLAVLGPSGSGKSTLLSCVLGLLRPDRGSVRVAGTEITKLGSRGLAKTRAESIGMVFQFGELLPELSPVENVALAAMLARKASADIYQRAQALLDELGVPEAKTSASLSGGERQRTAVARALINSPVLLLADEPTGALDAEARDKTAGMLFDVPKRHSCGMLLVTHDLAVAARADRVVSIVDGALETVSIKEAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAX2</accession>
    <name>D3QAX2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal RNA small subunit methyltransferase I</fullName>
            <ecNumber evidence="7">2.1.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">16S rRNA 2'-O-ribose C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">rRNA (cytidine-2'-O-)-methyltransferase RsmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rsmI</name>
        <name evidence="9" type="ordered locus">Snas_5133</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020339.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5133"/>
    <dbReference type="EnsemblBacteria" id="ADD44768">
        <property type="protein sequence ID" value="ADD44768"/>
        <property type="gene ID" value="Snas_5133"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5133"/>
    <dbReference type="eggNOG" id="COG0313">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044779_0_0_11"/>
    <dbReference type="OMA" id="RTMVFFE"/>
    <dbReference type="OrthoDB" id="1059309at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00096">
        <property type="entry name" value="TIGR00096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="8">
        <location>
            <begin position="9"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="288" mass="30724" checksum="19BDDF4CF5EC447A" modified="2010-04-20" version="1">MSHTDSPGKLLLIGAPLGNTEDASVRLGRELSAADVIAAEDTRRLRRLADELGLDISGAVTSYFEGNEKQRTPQLLERLKTGATVALITDGGMPSVSDPGFRLVRAAVDAGIPVTSVPGPSAVTTALAISGLPSDRFCFEGFLPRKDGERRTRLTELADERRTLVFFESPRRIDASLDALAEAFGGDRAAVLCRELTKTYEEIRRGGLAELAAGAREDPPRGEITLVVAGANPTRATDAASLAAAVRVLVDDGVDRKEALKRVAVDHGVPKRDVYDAVLAERSTDRPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB55</accession>
    <name>D3QB55_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1162"/>
    <dbReference type="EnsemblBacteria" id="ADD40872">
        <property type="protein sequence ID" value="ADD40872"/>
        <property type="gene ID" value="Snas_1162"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1162"/>
    <dbReference type="eggNOG" id="ENOG502Z94V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031194_0_0_11"/>
    <dbReference type="OMA" id="FECGWSW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="609" mass="68868" checksum="29C60499FED7A228" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB65</accession>
    <name>D3QB65_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Virulence factor Mce family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1172</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016453.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1172"/>
    <dbReference type="EnsemblBacteria" id="ADD40882">
        <property type="protein sequence ID" value="ADD40882"/>
        <property type="gene ID" value="Snas_1172"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1172"/>
    <dbReference type="eggNOG" id="COG1463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045966_2_0_11"/>
    <dbReference type="OMA" id="ATGCAFH"/>
    <dbReference type="OrthoDB" id="807474at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005693">
        <property type="entry name" value="Mce"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024516">
        <property type="entry name" value="Mce_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11887">
        <property type="entry name" value="Mce4_CUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00996">
        <property type="entry name" value="Mtu_fam_mce"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048833" evidence="2">
        <location>
            <begin position="25"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="3">
        <location>
            <begin position="33"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Mce4_CUP1" evidence="4">
        <location>
            <begin position="118"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="377" mass="39407" checksum="30AA6311F684520C" modified="2010-04-20" version="1">MRRANVAKLTAVIAAAALAGCSSAPLPGGEGGDGYQVAIEFADVTDLVPYSTVKVDDVTVGQVEEITVSEKWTAKVKIRVNDDVELPRNAIAALRQTSLLGEKFVELAPPTESKPAGSLSEGDSIPLSRTDKGAEVEEVLGAVALVLQGGGLEQLRTINTELSDMMQGREGEIKDSLGELDTFMTSLDDQREDIVTALEALEKLSGDLADQKETIGEALDAIAPGVTTLAKQKGMITEAITALGELGEVGSDVIEQSGDETVAILQDLQPVLENLVKAGDHFPQGLELAGSYPFPPNVSETIEDDFVNLYITLDGSLENVLGNTLGEKPIKQADPDNPESTPGGTEGGGIDPITGGIDDLLGGGITGDEDEDEEEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBK4</accession>
    <name>D3QBK4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3216</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018457.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3216"/>
    <dbReference type="EnsemblBacteria" id="ADD42886">
        <property type="protein sequence ID" value="ADD42886"/>
        <property type="gene ID" value="Snas_3216"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3216"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_288343_0_0_11"/>
    <dbReference type="OMA" id="WLHWYVA"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="931" mass="98817" checksum="2D76F3B6E3F5ADBC" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBK6</accession>
    <name>D3QBK6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018459.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3218"/>
    <dbReference type="EnsemblBacteria" id="ADD42888">
        <property type="protein sequence ID" value="ADD42888"/>
        <property type="gene ID" value="Snas_3218"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3218"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_10_0_11"/>
    <dbReference type="OMA" id="GNMIRIQ"/>
    <dbReference type="OrthoDB" id="1900922at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="137" mass="14891" checksum="E223AEF24FB2F33F" modified="2010-04-20" version="1">MDITIQSSFLPHTDAEASLAFYRDVLGFEVRGDVGNDRMRWITVGPVDQPGTSIVLEPPAVDPGVTDAERHTIEEMIAKGTYGYILLGTSDVDATFAKVKDAGGEVAHEPTDQPWGVRDCAFRDPAGNMVRIQQTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC24</accession>
    <name>D3QC24_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020484.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5279"/>
    <dbReference type="EnsemblBacteria" id="ADD44913">
        <property type="protein sequence ID" value="ADD44913"/>
        <property type="gene ID" value="Snas_5279"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5279"/>
    <dbReference type="eggNOG" id="ENOG503220F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145470_1_0_11"/>
    <dbReference type="OrthoDB" id="1695018at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009666">
        <property type="entry name" value="Uncharacterised_Ycf35"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06868">
        <property type="entry name" value="DUF1257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="136" mass="15264" checksum="608DE355F163EA58" modified="2010-04-20" version="1">MSHFTRVRTTLTDTATLAAALRELGFAEVEVHDTAQALHGHRGDVRPETAEVIVRRQHLGIASNDLGFARREDGSYEAIVSEFDRRKYGEAWMKKLLSTYGYLTAVAFAEQHGFAIATDEVETEGTRRLTLRRTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU44</accession>
    <name>D3PU44_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-quinone oxidoreductase subunit H</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NADH dehydrogenase I subunit H</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nuoH</name>
        <name evidence="8" type="ordered locus">Snas_1281</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cell membrane</location>
            <topology evidence="5 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the complex I subunit 1 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1281"/>
    <dbReference type="EnsemblBacteria" id="ADD40990">
        <property type="protein sequence ID" value="ADD40990"/>
        <property type="gene ID" value="Snas_1281"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1281"/>
    <dbReference type="eggNOG" id="COG1005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015134_0_0_11"/>
    <dbReference type="OMA" id="WSGWASN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01350">
        <property type="entry name" value="NDH1_NuoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001694">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1/FPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018086">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11432">
        <property type="entry name" value="PTHR11432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00146">
        <property type="entry name" value="NADHdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00667">
        <property type="entry name" value="COMPLEX1_ND1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00668">
        <property type="entry name" value="COMPLEX1_ND1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="402"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="447" mass="48335" checksum="FC652551A4534903" modified="2010-04-20" version="1">MTNVYALMAEGPDDTLAMFGNDPWWMILIKAVVVFAGLVVLTLLTIWFERKAVAWMQVRPGPNRHGPFGLLQSLADGLKLAFKEDLVPAGADKIVFILAPVISTVCAITAFSIIPLGPEVSIFGVVTPLQLTDLPVGVLLVLACSALGVYGIVLGGWASGSTYSLLGSLRAAAQVISYEIAMGLSIVAVFLTSGTLSTSGIVAAQQEGQTMTFGSVSFEIPGWYALLLLPSFIIFCISVVGETNRAPFDLPEAESELVGGFHTEYSSLKFALFFLAEYINMVTVSAMATTLFLGGWQAPFPASWWPGANEGWFPLIWFFGKVIVLLFGFVWLRGTLPRFRYDQFMRLGWKVLVPVNLVWIVALAGFYAGRESESLATRVSVIGGVGLLVLLALMFWPTRTEYKPPSEPDKGLGGFPVPPLDLEIPPSPSTKQLEAKREPVSAKEGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU96</accession>
    <name>D3PU96_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplK</name>
        <name evidence="11" type="ordered locus">Snas_1333</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016613.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1333"/>
    <dbReference type="EnsemblBacteria" id="ADD41042">
        <property type="protein sequence ID" value="ADD41042"/>
        <property type="gene ID" value="Snas_1333"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1333"/>
    <dbReference type="eggNOG" id="COG0080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074237_2_2_11"/>
    <dbReference type="OMA" id="HTLAYKT"/>
    <dbReference type="OrthoDB" id="1702697at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0488">Methylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L11_N" evidence="10">
        <location>
            <begin position="10"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="9">
        <location>
            <begin position="70"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD41042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="140" mass="15292" checksum="C063515B96861952" modified="2010-04-20" version="1">MSGKDTVRMTLELEAGNASVAELGKMLGQVGLNIREVKRAYDEATASQRGDIVPVVVTVEPDRSYRLRYKTPPTAFLIRKALGRKGSDRPGHEAAGELDQRRLREIAQRKLPDLNTSDVEAAMRMIAGTARSMGVTIAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUE9</accession>
    <name>D3PUE9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018533.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3294"/>
    <dbReference type="EnsemblBacteria" id="ADD42962">
        <property type="protein sequence ID" value="ADD42962"/>
        <property type="gene ID" value="Snas_3294"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3294"/>
    <dbReference type="eggNOG" id="ENOG5031MNQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075797_0_1_11"/>
    <dbReference type="OMA" id="WRTRNPG"/>
    <dbReference type="OrthoDB" id="1899949at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016566">
        <property type="entry name" value="UCP010219"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11361">
        <property type="entry name" value="DUF3159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="231" mass="25129" checksum="9680163549D96D00" modified="2010-04-20" version="1">MNLNALTSTSLSLFDAVGGWRTVAESMASRVLFLVTYLLTEEVLTAALVAVGGVLVFVVVRICTDRKYLAAVVELSVVCFSALLAGGTGHAANFYLPALFTNIGPLVVFLVSMLVRWPVIGLVVGTVRGERFAWRRDPVRRRRYQRCTAMFLAKFAIASAVMLPLYLAEHVTALGIANMLLTSPAAGVCVYVSWRILRVPTDPASLGSRCPSLRRHRGSSLARRLTTVIDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUF3</accession>
    <name>D3PUF3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3298"/>
    <dbReference type="EnsemblBacteria" id="ADD42966">
        <property type="protein sequence ID" value="ADD42966"/>
        <property type="gene ID" value="Snas_3298"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3298"/>
    <dbReference type="eggNOG" id="COG0859">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_700023_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="364" mass="38438" checksum="E86A13EB914740EE" modified="2010-04-20" version="1">MGQRLPYRRRAGESPPGPTPLLAKATMDGWRVDFLVRSETPGGPPAEPVHLGDLLLSLSLVRALSEATGSPPLSYHGDRGALMSRCDLPIAVAGTAPGSSITTAGSDVARVEVRPVRPPVWPGHEHHPDRLSTAMPIWLDPGDGLVDVHACLPSRLYLQAEQDLGVRLPADGMVAPTFGTRESAEPGHVVFVATTSSPDGKDFGHDGFIDLARELTKRSPMDLRFTLVTNDLDDGSAPAADLRLRVASGIAAEDCVDLFGTADLVVGNDTGLTHLAALTARADHGGPEVIGLYNIFSPLKWNTGSPRHHAIATAFSQMVALSDVDIYVNQYGSYIDPAVWADGALVDSVPPATVAAFAATCLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUN6</accession>
    <name>D3PUN6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epoxide hydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3385</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018620.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3385"/>
    <dbReference type="EnsemblBacteria" id="ADD43049">
        <property type="protein sequence ID" value="ADD43049"/>
        <property type="gene ID" value="Snas_3385"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3385"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_1_11"/>
    <dbReference type="OMA" id="ATIYWLT"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033961">
        <property type="term" value="F:cis-stilbene-oxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EHN" evidence="4">
        <location>
            <begin position="4"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="375" mass="42033" checksum="EE56AF6A17C62D60" modified="2010-04-20" version="1">MTQIRPFRIEIPQADLDDLNDRLARTRFTNELPPAQVASLPTAGPIQPGWQHGVPLSWVQDLVKRWRDDYDWRAWETKLNSHPHFITEIDGQDIHFVHVRSANPDAVPLILTHGWPNTFVEYFDLIDALSPDFHLVIPDLPGFGFSGPTNDTGWSANRVAKAWAELMSRLGYQRYGVHGNDAGAIVAPILGMVDAAHVIGVHVTQIFSFPKGDPGEFDDLSQDDIEYMQFVQGFLEYAIHDRTQQAQPQTLAHALADSPAGQLAWIGQLLGPLDPDIVLTNATIYWLTNTAASAARFYYENHHDTALANQEPTTTPIGLAGFAYDMKSIRKFAERDHKNIVAWSQFDRGSHWAAHDAGDLLAGDIRKFFTEHVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUX7</accession>
    <name>D3PUX7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF1232 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5369</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020572.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5369"/>
    <dbReference type="EnsemblBacteria" id="ADD45001">
        <property type="protein sequence ID" value="ADD45001"/>
        <property type="gene ID" value="Snas_5369"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5369"/>
    <dbReference type="eggNOG" id="COG3339">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1665686_0_0_11"/>
    <dbReference type="OrthoDB" id="2017850at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010652">
        <property type="entry name" value="DUF1232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06803">
        <property type="entry name" value="DUF1232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1232" evidence="6">
        <location>
            <begin position="101"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="162" mass="17516" checksum="065C34531F721F2C" modified="2010-04-20" version="1">MIVFGVVLMVLGGALFLTPIPTWTDELWLLPVGLIAAGFGLMIAGVVARVRRRLVKLRRSASSRTEVEAEGGPLRRLAAIPAMISSAWNRGDRSVSRSQTVLWLAAVVYLVSPIDLIPELLPVIGFADDIGLAAWLLGSLYAEAGNYLGQKRQREHGIDAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUX8</accession>
    <name>D3PUX8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5370</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45002">
        <property type="protein sequence ID" value="ADD45002"/>
        <property type="gene ID" value="Snas_5370"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5370"/>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_17_5_11"/>
    <dbReference type="OMA" id="LREHYHY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14659">
        <property type="entry name" value="Phage_int_SAM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="165"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="498" mass="56917" checksum="1FC9953AF79ED159" modified="2010-04-20" version="1">MGYSRCRKTSKGLKRYTAYYLDSRGDERSAGTFGKKKEADKAWQRAEGKVSEGRGGQLIRGRQTFKTYVEEKWLPNLSVEQSTLEGYTYVLYAHIMDYFETSRMMDIYANNIREWIKTLKSNGMTAANIQHVKTQLSSILTSAVKDEVIVGNPCLLVDIDPVPLKPLRIVTPEEFDIFHAALPDEMSKLLVETGIETGCRWGELSELRPKDFDFDTCVVTISRAVVQLVRKFHPEGKRFLVKEYPKDKEFRYFKVNRALCRRIQVHIEKNGLADDDLLFWYVPKQEAELPALDADPKTLGKTKPNEKGRTYQHGTTSAYTAAKCRCDHCKKAMAIYRAKRRAEGKDQPRKVRNWDTDGHIPKRWFRDRILRPALKKSGIAVDIAMHKLRHAHASWALKGGADLHIVKERLGHANISTTERYLHAMDEGDETALEAIESFRQSQRSKGRTQALVQIGTVDEQSHQGAMTTEQVLEEMKRIDQLQAHLRDQLSQSLSSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV74</accession>
    <name>D3PV74_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">infB</name>
        <name evidence="11" type="ordered locus">Snas_1421</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1421"/>
    <dbReference type="EnsemblBacteria" id="ADD41127">
        <property type="protein sequence ID" value="ADD41127"/>
        <property type="gene ID" value="Snas_1421"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1421"/>
    <dbReference type="eggNOG" id="COG0532">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006301_9_4_11"/>
    <dbReference type="OMA" id="QVRPEMI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="470"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="55"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="479"/>
            <end position="486"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="529"/>
            <end position="533"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="583"/>
            <end position="586"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD41127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="980" mass="101799" checksum="CF6537549DCF203B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVE3</accession>
    <name>D3PVE3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1492</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1492"/>
    <dbReference type="EnsemblBacteria" id="ADD41196">
        <property type="protein sequence ID" value="ADD41196"/>
        <property type="gene ID" value="Snas_1492"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1492"/>
    <dbReference type="HOGENOM" id="CLU_2083416_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="117" mass="12514" checksum="E9BD66B18FF01ACF" modified="2010-04-20" version="1">MTAVDPRDPNRKLAINLTPVERTAGLLGEQAEAIAERTRLLVVDESLGNSFGSRDVDAAGSYRNTAEVFGDVAKLLRDELNRGKRILTTVTGDYRATDADNAAAIARVTDTAEGGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVJ6</accession>
    <name>D3PVJ6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carbamoyltransferase</fullName>
            <ecNumber evidence="8">6.2.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Snas_3446</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + C-terminal L-cysteinyl-[HypE protein] + carbamoyl phosphate + H2O = AMP + C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + diphosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:55636"/>
            <dbReference type="Rhea" id="RHEA-COMP:14247"/>
            <dbReference type="Rhea" id="RHEA-COMP:14392"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:76913"/>
            <dbReference type="ChEBI" id="CHEBI:139126"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>an acyl phosphate + H2O = a carboxylate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; [NiFe] hydrogenase maturation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the carbamoyltransferase HypF family.</text>
    </comment>
    <dbReference type="EC" id="6.2.-.-" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018681.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3446"/>
    <dbReference type="EnsemblBacteria" id="ADD43110">
        <property type="protein sequence ID" value="ADD43110"/>
        <property type="gene ID" value="Snas_3446"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3446"/>
    <dbReference type="eggNOG" id="COG0068">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009164_0_0_11"/>
    <dbReference type="OMA" id="CGPRLSW"/>
    <dbReference type="OrthoDB" id="48295at2"/>
    <dbReference type="UniPathway" id="UPA00335"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046944">
        <property type="term" value="P:protein carbamoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004421">
        <property type="entry name" value="Carbamoyltransferase_HypF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041440">
        <property type="entry name" value="HypF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011125">
        <property type="entry name" value="Znf_HypF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17788">
        <property type="entry name" value="HypF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07503">
        <property type="entry name" value="zf-HYPF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006256">
        <property type="entry name" value="CMPcnvr_hdrg_mat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="SSF54975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00143">
        <property type="entry name" value="hypF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00150">
        <property type="entry name" value="ACYLPHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="10">
        <location>
            <begin position="11"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="YrdC-like" evidence="11">
        <location>
            <begin position="207"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD43110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="764" mass="81846" checksum="68FA0BED6058CD07" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVL2</accession>
    <name>D3PVL2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">H(+)-transporting two-sector ATPase</fullName>
            <ecNumber evidence="11">3.6.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_3462</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.14" evidence="11"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018697.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3462"/>
    <dbReference type="EnsemblBacteria" id="ADD43126">
        <property type="protein sequence ID" value="ADD43126"/>
        <property type="gene ID" value="Snas_3462"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3462"/>
    <dbReference type="eggNOG" id="COG1155">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008162_3_1_11"/>
    <dbReference type="OMA" id="RIVKTFW"/>
    <dbReference type="OrthoDB" id="875807at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006754">
        <property type="term" value="P:ATP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031686">
        <property type="entry name" value="ATP-synth_a_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022878">
        <property type="entry name" value="V-ATPase_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607">
        <property type="entry name" value="PTHR43607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16886">
        <property type="entry name" value="ATP-synt_ab_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="10">
        <location>
            <begin position="217"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD43126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="575" mass="61247" checksum="87B06BEE4FC95CE6" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVL8</accession>
    <name>D3PVL8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3468</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3468"/>
    <dbReference type="EnsemblBacteria" id="ADD43132">
        <property type="protein sequence ID" value="ADD43132"/>
        <property type="gene ID" value="Snas_3468"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3468"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_10_2_11"/>
    <dbReference type="OMA" id="NEWLVKP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="102"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="72"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="406" mass="43065" checksum="23ADCA4CB6D9EF5E" modified="2010-04-20" version="1">MPSLGADMDAGTLTEWLVAPGDHVSKGDIVAVVETAKADMEVECFDAGVIGELLVHPGARVPVGTVLATIVTDDGGSPGEPAAAPAIEPAPPRADAPPEPPRVSPLVRHLARENHVDLAKVPATGPDGTVTRADLDRVLHRRRISPLARRLATELKVDLARIDADGPIHARHVREAATHRHPAERSTSAAREATARLMARSKREIPHYYLAATIDLGPAVDWLTDLNRRLPVSQRVLPAALLLVATARAAATVKDLNGHWIDDRFQAADRIRLGLAVSVRGGGLVVPGIDDAAALSVPEMMDRVRDLATRARTGQLRAGELADPSITVSNLGDTGVDSVLGVIYPPQVALVGFGAITERPWAVNGLLGVRPVVTASLSADHRVTDGAVGARFLNHIDRLLREPEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVQ5</accession>
    <name>D3PVQ5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Condensation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3506"/>
    <dbReference type="EnsemblBacteria" id="ADD43169">
        <property type="protein sequence ID" value="ADD43169"/>
        <property type="gene ID" value="Snas_3506"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3506"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_632998_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="36"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="433" mass="48076" checksum="0102ECF9A37169DC" modified="2010-04-20" version="1">MERGLTQAQRYSLTWLRDQRELGTDVPANMIVMPIRFRTRISDRQIQTTIGRLVERHESLRTGFCLHTHECGPVTFVQKGISVSVKVRRVNDTSMASDDVASAIDEIANTRLPLSQPPLLTTRILRAGFADVLVLVGVDHLVFDGASATPFFDEFVDLLANPATALPPARQFADWIAWQRTHLDGPAGKELLDYWRGTLGEAGPMPRLNVPTDPDSGRTSMQTHAVRVSSVTPECLRTVDIKETVTPFMVAMNVVARACAHVLDLPDLVIHTPTANRGSMAAKGVIGWLAHSMPVRVRIGSRTTFRQSLSQVRRAVLGAITHSDMPLLVLHQHLRPDTFDDIRLGRIYFAYEKPSSTVRRFRESTAELYTVPGGYASSTVGNGITIVVTEFRDHLAVRAVAQPDIATPILHQLIDRIEQEFGALDRPKESRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVS0</accession>
    <name>D3PVS0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylmuramoyl-L-alanine amidase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3521"/>
    <dbReference type="EnsemblBacteria" id="ADD43184">
        <property type="protein sequence ID" value="ADD43184"/>
        <property type="gene ID" value="Snas_3521"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3521"/>
    <dbReference type="eggNOG" id="COG3023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079355_2_0_11"/>
    <dbReference type="OMA" id="CRHHGWT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="1">
        <location>
            <begin position="24"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="181" mass="19016" checksum="5BA827C329221B44" modified="2010-04-20" version="1">MATIPWLVEVLRADGVEVVEEGDWQNHMRPGEFAPIGVLWHHTAGPPSSAENPAPSLGTVINGRPDLPGPLAQALVDFNGVFHVISAGRSNHAGKSGGSGPIPAGDGNALMVGWEIDYDGVNQQMSPAQYQASLKATAAVLRRLGTDAEHARGHKETSTTGKIDPSFVDLAAMRAEVAKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW56</accession>
    <name>D3PW56_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1509</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016784.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1509"/>
    <dbReference type="EnsemblBacteria" id="ADD41213">
        <property type="protein sequence ID" value="ADD41213"/>
        <property type="gene ID" value="Snas_1509"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1509"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="HVSRVMV"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="151"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="24246" checksum="33FFD74D9524F272" modified="2010-04-20" version="1">MNPIRLVVADDQKLIRMALSTLAAGEPDIELVAEAADGKAALTAIRDHSPDVLLLDIRMPIMGGLEVLRHIETDPDATVRVIMMTTFDIDQYVFESLEHGAAGFLTKDTDPEFILHAVRVVAAGESLLSPGVTRRVIDRFTRGRHARTGEPHPGLDSLTARETEILGWVATGLSNDEIAERLVVSPATVRTHVGRAMMKLRARDRAQLVVIAYRSDIDIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWG4</accession>
    <name>D3PWG4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, TrmB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018757.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3523"/>
    <dbReference type="EnsemblBacteria" id="ADD43186">
        <property type="protein sequence ID" value="ADD43186"/>
        <property type="gene ID" value="Snas_3523"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3523"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_1_1_11"/>
    <dbReference type="OMA" id="TRTILFH"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="162" mass="17740" checksum="5DE6B8B9AFE97381" modified="2010-04-20" version="1">MSTGPRQPRSDDRAALVERLTNAGRRTSDAAVMFHTALSQHLGIGVSDWKILGLLDQHGPLSAGELSRHSGLAPASITGAVDRLVKRGYVKRLKAEGDARRVLVALDSQLLQGVETQFAAYFRRLTELLERYDDDQLALLAEFLDTNATLMSEATAEISQDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWX7</accession>
    <name>D3PWX7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5570"/>
    <dbReference type="EnsemblBacteria" id="ADD45201">
        <property type="protein sequence ID" value="ADD45201"/>
        <property type="gene ID" value="Snas_5570"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5570"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_15_5_11"/>
    <dbReference type="OMA" id="IVFNARN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="198" mass="21680" checksum="84DE496D32DF574E" modified="2010-04-20" version="1">MRSFIEQARRAQIIGAAIETIAEHGYANASLARIAKHADISKGVISYHFAGKEELIEQVVTQVFSAIVEEVAPRVTAAPGPREALREHIIAVGEYVLAHRTQLMALSEIINGARSTEGKPLYGISSSEDLYESLELYFASGQDSGVFRHFDRRVMAVTLQSAIDGAFGYWVVHPEHDLAAHMTELADHIDRAVLADPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX10</accession>
    <name>D3PX10_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5604</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020805.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5604"/>
    <dbReference type="EnsemblBacteria" id="ADD45234">
        <property type="protein sequence ID" value="ADD45234"/>
        <property type="gene ID" value="Snas_5604"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5604"/>
    <dbReference type="eggNOG" id="COG2159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039329_1_1_11"/>
    <dbReference type="OMA" id="TTNYKAI"/>
    <dbReference type="OrthoDB" id="1832218at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="4"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="336" mass="38444" checksum="30FECEC0499752C0" modified="2010-04-20" version="1">MKIDAYSHILPAPYFERMRQLVANPGMFKRWLELPALHDIDVRLRMMEEFGDDYQQVLTLSSPPIEVLATPEQSPGLARLANESMLELCQKYPERFPAFVASLPMNNPDAVFEELDYAIDELGARGVQVFTNVNGKPLDEPEYLEIFERMAQRDLPVWMHPARGPGHADYLTESTSKYEIWWALGWPYETSVAMSRLVFSGILERYPDLKIITHHMGAMIPSLEGRIGLGWSDQLGSRTAEVDYAKLREERLPLPLVDYFRRFYADTALSGSAIGVRCGLDFFGAERVLFGSDCPFDPQGGPMYIREIIRVVDELDITDAERECVYHRNVRGLMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX23</accession>
    <name>D3PX23_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Abortive infection protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020818.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5617"/>
    <dbReference type="MEROPS" id="G05.004"/>
    <dbReference type="EnsemblBacteria" id="ADD45247">
        <property type="protein sequence ID" value="ADD45247"/>
        <property type="gene ID" value="Snas_5617"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5617"/>
    <dbReference type="eggNOG" id="COG1266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064706_0_1_11"/>
    <dbReference type="OMA" id="GEELGWQ"/>
    <dbReference type="OrthoDB" id="1623593at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042150">
        <property type="entry name" value="MmRce1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35797">
        <property type="entry name" value="PTHR35797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="279" mass="29007" checksum="ACE31623FF7CA75C" modified="2010-04-20" version="1">MSTVPIAPPSQSLAHRFSLPTFLLVTLLGGWVAVTPLWLFGGNAALGIAGMAMMSTPALGVLAARRRGVRFRDLAHATGLTLGPRRTRTIAVAIAVLLGLPALAGIAIAIAAGSGLATLNPGMSGALLAVVMTPLTTFLMVPTAFGEEWGWRGLLLPHLMERHSRRKAIVVTGLIWCVWHAPLGLFFGASAPLYFIPLSAMFMVFAGPVSWARLATGSVWPAVLAHAGLNASAATLFTSLSSGATPADIGIGAVVGMALWAAALLLTTAILFRTKHQHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX74</accession>
    <name>D3PX74_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1634</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016908.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1634"/>
    <dbReference type="EnsemblBacteria" id="ADD41337">
        <property type="protein sequence ID" value="ADD41337"/>
        <property type="gene ID" value="Snas_1634"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1634"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_1_3_11"/>
    <dbReference type="OMA" id="DRWAIAC"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1058" mass="114168" checksum="7696BC66E6312933" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXA3</accession>
    <name>D3PXA3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1664</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1664"/>
    <dbReference type="EnsemblBacteria" id="ADD41366">
        <property type="protein sequence ID" value="ADD41366"/>
        <property type="gene ID" value="Snas_1664"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1664"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_60_4_11"/>
    <dbReference type="OMA" id="WIMGITI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="31"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="403"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="428" mass="44068" checksum="41F9F690543E2FE4" modified="2010-04-20" version="1">MPPTPTADPPRTPTPAAEPPPRSGWSRVPRTVWVLAAARFVSGTATFVAVYLFLYLTGPRGLSLTAAGLISGAVGAGMLAGTFTGGWFSDRFGHRRTMLVASTIGGLSLLAVPWLPIGVLAVTMPLGSYATGTADVAQSALVAEAVPAGDRRTAIAITRAASNAGFVIGPPLGALLASVSYTWLFVVQALVMLTVRQVAARLLPAAPTRKAAAPSDGGLWASLRAGRTLLLFLPAVLLADLVYRQLYSTLPVYLRDSGHGVGLYATLIAVGSGVILCLEIPVTLALRRLPSLRIIATGYLLVGAGFGLLGVSTSTWVLVIAMLVVTAGEILYKTTATAHVVDAAPPQLLARYQGLYTGASISGVVLAPPIGAFTYAISPASVWPLCTAVAVIAAGLALWSGRSRGPGRRWQAAAPRSSGVRGSQDATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXD1</accession>
    <name>D3PXD1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1694</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016965.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1694"/>
    <dbReference type="EnsemblBacteria" id="ADD41394">
        <property type="protein sequence ID" value="ADD41394"/>
        <property type="gene ID" value="Snas_1694"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1694"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_0_1_11"/>
    <dbReference type="OMA" id="KMSLYRY"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="27"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="252" mass="28026" checksum="7F863E2EA47C0D0E" modified="2010-04-20" version="1">MTDVDIPVELRRLWRIPADTNLGRTAELDVERVVRTAVDLADRHGLDGVSLPKIAKTLGFTTMSLYRHVGSKEELLTLMFDAAFADFPEPATEPGQWRLGLHTWTAQQRDLYDRRPWLVRMPILAPPTGPHQVAFMDGGLRLLRPTGLEWPQKVGVLMLLTGWARHAAQLSHDLAAGREASVDQGAAERAWSRSLAHLVEPDRFPDMAALLDSDTFLAPRPETTAAEQADFVFGLERILDGVAELIASRARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXG8</accession>
    <name>D3PXG8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1733</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1733"/>
    <dbReference type="EnsemblBacteria" id="ADD41431">
        <property type="protein sequence ID" value="ADD41431"/>
        <property type="gene ID" value="Snas_1733"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1733"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="288"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="385" mass="40551" checksum="D7E1940E09136AD1" modified="2010-04-20" version="1">MRTWRPVLAGAGTLALIFGVLVLPADPWLFMVAPTLGCLVTAALMASWPLSRAWVPLASGLVGAVSLGVTAVMTALRLGAGEPSPVAPTSLWLMLEPAVLLIFVYLPVRWSRPSAAVWTGGAAGLGVALNVQRYITDTSFGERVAASALWMIFAVATGTVAWYLRSLAEARGRAIAEARQTQRLELAADLHDFVAHDVSEIVAQAQAGRMVLAPDPRLAEVLERIEVAGLRALASMDRTVHMLRETDGATVAAPGVLADLDELVSRFESAGTTAARLDNGFTGSAPREIAAVAYRVVVEALTNVRRHAATATRVTVALAERDDHLVVTVTDDGRGETTASDRTSAGTGLAGLSERVTALGGDLTTATIRPHGWRLTARLPLTEGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXU7</accession>
    <name>D3PXU7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3770</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018998.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3770"/>
    <dbReference type="EnsemblBacteria" id="ADD43427">
        <property type="protein sequence ID" value="ADD43427"/>
        <property type="gene ID" value="Snas_3770"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3770"/>
    <dbReference type="eggNOG" id="COG0410">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="IMMQKIM"/>
    <dbReference type="OrthoDB" id="1475841at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030660">
        <property type="entry name" value="ABC_branched_ATPase_LivF/BraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039137">
        <property type="entry name" value="ABC_branched_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="237" mass="25658" checksum="FABA7F20080CBF4C" modified="2010-04-20" version="1">MTAILEIRDLSVYYGRIKALHDISLTVGEGEIVALIGTNGAGKTTTMKAISGLRAAHGTIRFQGKDITKVKAHHRVGLGISQSPEGRGVFPGMTVRENLMLGAFTRKDKAAIATDLDRVLHLFPRLKERFTQAAGTMSGGEQQMLAMGRALMSRPKLLLLDEPSMGLAPMLIQQIFEIITEIREQGTTVLVVEQNAKQALTRADRAYVLETGDITRTGTGAELLADNSIRDAYLGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXW1</accession>
    <name>D3PXW1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5660"/>
    <dbReference type="EnsemblBacteria" id="ADD45290">
        <property type="protein sequence ID" value="ADD45290"/>
        <property type="gene ID" value="Snas_5660"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5660"/>
    <dbReference type="HOGENOM" id="CLU_168298_2_0_11"/>
    <dbReference type="OMA" id="QLCAIMP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022536">
        <property type="entry name" value="EspC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10824">
        <property type="entry name" value="T7SS_ESX_EspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="106" mass="11730" checksum="566F33ACFDCCA8F9" modified="2010-04-20" version="1">MKVVAKKLRDHADSIDDAIDAFKLSEAASKHVKAGNDAFGTLCQWLPPILDAKRDRLDGLMKKAKDILTDDAKAMRTIADEYETTDKDNAVEVEKTIGDLKDVGWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY66</accession>
    <name>D3PY66_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1713 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5765"/>
    <dbReference type="EnsemblBacteria" id="ADD45395">
        <property type="protein sequence ID" value="ADD45395"/>
        <property type="gene ID" value="Snas_5765"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5765"/>
    <dbReference type="HOGENOM" id="CLU_209136_2_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013177">
        <property type="entry name" value="COX24_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08213">
        <property type="entry name" value="DUF1713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01155">
        <property type="entry name" value="DUF1713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1713" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="33" mass="4158" checksum="8156B460C1929EF5" modified="2010-04-20" version="1">MGSVVKKRRKRMAKKKHRKLLRRTRVQRRRQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYN5</accession>
    <name>D3PYN5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3812</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019039.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3812"/>
    <dbReference type="EnsemblBacteria" id="ADD43468">
        <property type="protein sequence ID" value="ADD43468"/>
        <property type="gene ID" value="Snas_3812"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3812"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_15_11"/>
    <dbReference type="OMA" id="ARLCHRT"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017205">
        <property type="entry name" value="Sig_transdc_His_kinase_ChrS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037434">
        <property type="entry name" value="STHK_ChrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="185"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="402" mass="42824" checksum="0E7CCD789F3DCD60" modified="2010-04-20" version="1">MNARLWVDRAMHAAFFLLLASSAARLVARHEVTGLTVAALVGSLLLAVVYAGGAAAGYTTARWRYVWFGAVVVLWLVTVELAPSFAWCAVPLYFLALRLLPGRVTIAVAVVLTLAVIVGGVRIADVVEPSLFLAPIGIAVMIAAFFWLLNHEITQRQRLIDDLAATRDSLAASQREAGMLAERERLSREIHDTLAQGLSSMGMLLQAAGRVWGTDPDAAREHVERAGAVAAENLDEARRFVRDLRPPRLDDTSLAEALRVLCADVDRENPVAVRFRLEGVETTVDDRVRLAVLRVAQSALSNVVEHAGASAAVVTLSFLGAELSLDVVDDGAGFPVGEPVPGDGLARADVGSGSGPQRGYGIPGMRDRLAELGGELTIENTPGEGTALAARIPLPPERKRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYQ0</accession>
    <name>D3PYQ0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Holliday junction ATP-dependent DNA helicase RuvA</fullName>
            <ecNumber evidence="8">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ruvA</name>
        <name evidence="10" type="ordered locus">Snas_3827</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Forms a complex with RuvB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RuvA family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019054.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3827"/>
    <dbReference type="EnsemblBacteria" id="ADD43483">
        <property type="protein sequence ID" value="ADD43483"/>
        <property type="gene ID" value="Snas_3827"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3827"/>
    <dbReference type="eggNOG" id="COG0632">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087936_2_1_11"/>
    <dbReference type="OMA" id="VGMAVQC"/>
    <dbReference type="OrthoDB" id="1370858at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009379">
        <property type="term" value="C:Holliday junction helicase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14332">
        <property type="entry name" value="UBA_RuvA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00031">
        <property type="entry name" value="DNA_helic_RuvA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013849">
        <property type="entry name" value="DNA_helicase_Holl-junc_RuvA_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000085">
        <property type="entry name" value="RuvA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011114">
        <property type="entry name" value="RuvA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036267">
        <property type="entry name" value="RuvA_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07499">
        <property type="entry name" value="RuvA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01330">
        <property type="entry name" value="RuvA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46929">
        <property type="entry name" value="SSF46929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00084">
        <property type="entry name" value="ruvA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="HhH1" evidence="9">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="9">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="200" mass="20768" checksum="CC55C9506D0476C6" modified="2010-04-20" version="1">MIASLTGTVTHVSTSTATITVGGVGMSVRATPGTLANLRVGGESTLYTTLVVREDSLTLYGFEAPDERDLFELLQTASGVGPRLAQAALAVHPPATVRHAIASGDTATLTRIPGVGKKGAERLVLELKDKIGALPGSMATEPKAGRPVSWRDQVQQGLMSLGWSAKDANGAITKLDSQVDGEAVDIQGLLKQAIRLLGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYV4</accession>
    <name>D3PYV4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA ATPase central domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3882</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019108.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3882"/>
    <dbReference type="EnsemblBacteria" id="ADD43537">
        <property type="protein sequence ID" value="ADD43537"/>
        <property type="gene ID" value="Snas_3882"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3882"/>
    <dbReference type="eggNOG" id="COG2256">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017985_0_3_11"/>
    <dbReference type="OMA" id="RIILSQC"/>
    <dbReference type="OrthoDB" id="977094at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="58"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="448" mass="47363" checksum="57FA1665CA149AD0" modified="2010-04-20" version="1">MEGPGLFDIPETAPRTEEPAADAPLAARMRPATLDELVGQQHLLTPGSPLRQLVGGDAPLSVILWGPPGCGKTTVANLVARATDRRYVPMSALNAGVKDVRAVIETARATRRRGGAPTVLFIDEVHRFTKTQQDALLAAVEDRTITLLAATTENPYFSVVSPLLSRCVLLTLEPLTEDDIRALVDRALSDERGLGGEVALEPEAADHLVRLAAGDARKALTALEAAAASAKAAGTTVVDLATAESAVDVAAVRYDRDGDSHYDIASALIKSLRGSDVDAALHWLARMIVAGEDPRFIARRLVIFASEDVGMADPTALQTAVAAAEAVAFIGMPEGQLTLAHAVVHLATAPKSNAVTAAIGAAITDVKNGHTGPVPPGLRDSHYAGAKNLGHGETYRYPHDDPRAVVTQQYAPDAVHRNVYYRPTDHGAENGLASRMEKLRAIVWGSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZF7</accession>
    <name>D3PZF7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4132 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ADD41631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="protein sequence ID" value="ADD41631"/>
        <property type="gene ID" value="Snas_1935"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1935"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009738_1_0_11"/>
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    <dbReference type="OrthoDB" id="325309at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025406">
        <property type="entry name" value="DUF4132"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13569">
        <property type="entry name" value="DUF4132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4132" evidence="1">
        <location>
            <begin position="411"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="837" mass="93912" checksum="553DED5D7EDA3EEE" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0A0</accession>
    <name>D3Q0A0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6003"/>
    <dbReference type="EnsemblBacteria" id="ADD45629">
        <property type="protein sequence ID" value="ADD45629"/>
        <property type="gene ID" value="Snas_6003"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6003"/>
    <dbReference type="eggNOG" id="ENOG5032VCE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121293_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="173" mass="19782" checksum="769C9E28CF1E4664" modified="2010-04-20" version="1">MNIAERLDKLSIRSSSPDGNIRSILTGRTNLKLEFRSGGYEAYTERELEHQLSRLATLTWTSYRRGYTEIVTSAGLEVVFEPGDEWNSHDREYQQARLEVEGRGESGDGTVRTRTQALLRWQFKIKDGTVKRLPEADFTREVLVAVRLAIKDYRSQSSELRQKYFGPGFAMGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0D5</accession>
    <name>D3Q0D5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015370.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0077"/>
    <dbReference type="EnsemblBacteria" id="ADD39799">
        <property type="protein sequence ID" value="ADD39799"/>
        <property type="gene ID" value="Snas_0077"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0077"/>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016537_0_0_11"/>
    <dbReference type="OMA" id="MWEWFFA"/>
    <dbReference type="OrthoDB" id="796556at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="585" mass="63715" checksum="F85E8CC76F1923CE" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0D7</accession>
    <name>D3Q0D7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0079</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015372.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0079"/>
    <dbReference type="EnsemblBacteria" id="ADD39801">
        <property type="protein sequence ID" value="ADD39801"/>
        <property type="gene ID" value="Snas_0079"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0079"/>
    <dbReference type="eggNOG" id="ENOG5034606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_789650_0_0_11"/>
    <dbReference type="OrthoDB" id="2182994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="351" mass="37764" checksum="B6A23192CA235578" modified="2010-04-20" version="1">MNDDEREAARLLEPLRQPEPPATSAVDVDRAMRTGRRTIRVRQVAGTLACVVAVLGIAFTVTVPYYHSPPAEETTSEFGVTTQEFAIGSAGGFTPLTYETGRSRQRATLTTQDGATDAVVTLYPKGRVPRVDGETWKPTGGTAPDVKGGAAVWPSEPVFGDDAVELAWQWRPDAWAFVSVTGPEADQDRAHKVALSVEPGADIDVAVPATYPTPHPGTVQESAVISTLRSIGDHERAERIYQVRYRASGDDSDWITVGVREPAPDTDESTTVDDRPALVEKNKVTFLDGTGLFVEVSDESVLDEPLTDFAARVELKSDLEWSPPPLSPSDMPTSSSETPTDSSTETASPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Y9</accession>
    <name>D3Q0Y9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4087</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4087"/>
    <dbReference type="CAZy" id="GH43">
        <property type="family name" value="Glycoside Hydrolase Family 43"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43739">
        <property type="protein sequence ID" value="ADD43739"/>
        <property type="gene ID" value="Snas_4087"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4087"/>
    <dbReference type="eggNOG" id="COG3507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054030_0_0_11"/>
    <dbReference type="OMA" id="HYYLIAS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048148" evidence="5">
        <location>
            <begin position="31"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="3">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="357" mass="38186" checksum="E2CEE8A5A7D5DB19" modified="2010-04-20" version="1">MKKKRLRLAMLAVLGVVGLAAAAVATPSLADSLSQDGSEKAADPKPVYNAQFADPAVTWTGEEYVGVSTGGLAPMATAPTARGPWKHKHGGLERLPKWAKKDGGVWAPAIQHVKGDTYVMYYAAKVSGLADANQRCIGVAVSTKGADARYTPVDSKPLVCPPGADHPGSSQPVTGGVGFIDPSTFTTKGGKNVLMFKSQKPNPGTKLWSLELNDNWTKPTSSSKVLISRAKGQIENPEMIVRGGHYYLIASYDNWANCSYKTVWLRNGSPRTGWKFPSGFPSKTTSKGGTLIKSRDGMCGPGGMTLTKHGDKREFFLHAYRDANGNGKKDSNTRRMYGGELVFSGGIPKLKSFYSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q136</accession>
    <name>D3Q136_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_4135</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4135"/>
    <dbReference type="EnsemblBacteria" id="ADD43786">
        <property type="protein sequence ID" value="ADD43786"/>
        <property type="gene ID" value="Snas_4135"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4135"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_35_5_11"/>
    <dbReference type="OMA" id="WIEHHQF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033068">
        <property type="term" value="P:macrolide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015083">
        <property type="entry name" value="Polyketide_synth_docking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08990">
        <property type="entry name" value="Docking"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 7" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="1952"/>
            <end position="2027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1902"/>
            <end position="1946"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7">
        <location>
            <position position="1987"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="2108" mass="223297" checksum="CC55DA790005B3EB" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1A7</accession>
    <name>D3Q1A7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021258.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6063"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45687">
        <property type="protein sequence ID" value="ADD45687"/>
        <property type="gene ID" value="Snas_6063"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6063"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027797_0_0_11"/>
    <dbReference type="OMA" id="FHGHEVC"/>
    <dbReference type="OrthoDB" id="212862at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048790" evidence="1">
        <location>
            <begin position="32"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="373"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="524" mass="56181" checksum="9F26857C53604DD8" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1I2</accession>
    <name>D3Q1I2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bacterial proteasome activator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0109</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Bpa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0109"/>
    <dbReference type="EnsemblBacteria" id="ADD39830">
        <property type="protein sequence ID" value="ADD39830"/>
        <property type="gene ID" value="Snas_0109"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0109"/>
    <dbReference type="eggNOG" id="ENOG502ZPJ4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111456_0_0_11"/>
    <dbReference type="OMA" id="TDMVEQP"/>
    <dbReference type="OrthoDB" id="1767315at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019695">
        <property type="entry name" value="Proteasome_act"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10759">
        <property type="entry name" value="DUF2587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="205" mass="22233" checksum="0A6B960A03A6942D" modified="2010-04-20" version="1">MTDDNTGTDKVVEPEETADTEEAEEAEQATVLVMGPDGKPVGTMTVDPESGEPQDPSKLVEQPAKVMRVGSMVKQLLEEVRSASLDEAGRKRLKEIHARSIAELEEGIAPELREELERLSLPFDDDTTPSESELRIAQAQLVGWLEGLFHGIQAALMAQQMAARMQLEQMRRGGMAALPAGSQLPPGVQMMANDDEHSGGPGQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1N9</accession>
    <name>D3Q1N9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0167</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015458.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0167"/>
    <dbReference type="EnsemblBacteria" id="ADD39887">
        <property type="protein sequence ID" value="ADD39887"/>
        <property type="gene ID" value="Snas_0167"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0167"/>
    <dbReference type="eggNOG" id="COG1510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120349_2_1_11"/>
    <dbReference type="OMA" id="HERIRNM"/>
    <dbReference type="OrthoDB" id="1646730at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="165" mass="18826" checksum="4E5A63B2D94248B5" modified="2010-04-20" version="1">MPELSIAERELVGRFGVFVEMSGGQRIAGMLVGYLLICKPEHQSITEMADALAISKASVSTVIRQLQQGLKVERVPVPDSRQHYYRLAGGGDWTEILRTRWKFLNAGRDVAAAGLRLVGDDPDRRERMQEFADFLDFLVEEFSPELVSRWETYRNKRTAEREAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1P9</accession>
    <name>D3Q1P9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase dimerization and phosphoacceptor region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0177</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0177"/>
    <dbReference type="EnsemblBacteria" id="ADD39897">
        <property type="protein sequence ID" value="ADD39897"/>
        <property type="gene ID" value="Snas_0177"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0177"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="NTHEFRL"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="3">
        <location>
            <begin position="189"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="157"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD39897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="386" mass="41101" checksum="0C5BFF832EDCADBB" modified="2010-04-20" version="1">MERDAEAEPADTSTGGRWDPAGLVLTVLPALAAFAGGLAQLYWVLLAGPVGTMRWVDIGCGAAACFVLLFRSRARTGIAIALAVVAAFAATGGVANMVALYGVARYRRLPVALAVGAADVLAGYCFWLVYPENNKLSLTLVVNVAIVAAIVAWGAMRQTQESLLLSYRERAERAEREQRLRETQIRQAERTRIAREMHDVVTHRISLVALHAGGLMVDPEPKIDVVRGSAELIYGSARQALEELRLALGALRADEPTSLEQPGLDRIQDLVEDALRAGQEVELDMDPAIVETAPPGIGRDAYRFVQEGLANVRKHAPNAVAVVTVAAADGVLRVRVVNEMVDGSLGVPGAGAGLIGLRERADLAGGTLSHGPVDGRFELVGELPWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1V1</accession>
    <name>D3Q1V1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chromosome partition protein Smc</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">smc</name>
        <name evidence="9" type="ordered locus">Snas_2124</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for chromosome condensation and partitioning.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SMC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017389.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2124"/>
    <dbReference type="EnsemblBacteria" id="ADD41818">
        <property type="protein sequence ID" value="ADD41818"/>
        <property type="gene ID" value="Snas_2124"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2124"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001042_2_0_11"/>
    <dbReference type="OMA" id="HNKIAME"/>
    <dbReference type="OrthoDB" id="1149850at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01894">
        <property type="entry name" value="Smc_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011890">
        <property type="entry name" value="SMC_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="SSF75553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02168">
        <property type="entry name" value="SMC_prok_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048559" description="Chromosome partition protein Smc" evidence="7">
        <location>
            <begin position="18"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="domain" description="SMC hinge" evidence="8">
        <location>
            <begin position="512"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="731"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="167"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="355"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="418"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="859"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="737"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="32"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD41818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1191" mass="128885" checksum="6A3E4FE02BB5CD79" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q205</accession>
    <name>D3Q205_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Proline--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="7">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">proS</name>
        <name evidence="9" type="ordered locus">Snas_2180</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017443.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2180"/>
    <dbReference type="EnsemblBacteria" id="ADD41872">
        <property type="protein sequence ID" value="ADD41872"/>
        <property type="gene ID" value="Snas_2180"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2180"/>
    <dbReference type="eggNOG" id="COG0442">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001882_4_2_11"/>
    <dbReference type="OMA" id="EVYWVTH"/>
    <dbReference type="OrthoDB" id="665824at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PTHR43382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="41"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD41872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="468" mass="51323" checksum="CC03975E4A384B77" modified="2010-04-20" version="1">MARVLTPQNEDFPRWYQDIVAKAELAENGPVKGQQVIRPTGFALWERMVAEMDDRIKETGAENASFPLLIPQSYLSKEAQHVEGFAPECWTVTHAGGKELEEPVVVRPTSETVIGESMSRWVKSYRDLPLLLNQWCNVMRYEMRTRLFLRSSEFLWQEGHTAHATFEDAAAYNRRILHEVYQDFMENVVALPVFTGLKTAAERFAGAINTFTCEAMMRDGKALQAGTAHELGQNFAKAFDIQYLGSDGKQHHAWTTSWGVSTRMVGALIMGHGDDSGLRVPPRLAPVQAYVMTVKDGEGVSEAAAKTHAALRAAGVRSKLNDRSDVAFGRRAVDAELKGYPVRLEIGPRDVAEGKAMLVRRIAGTKTQVSLDGVTEAVADALAADQDALYAEALKFREDHTSDVTTLDEAIEASATGFARLPWDACGTEGETRAAASAVTVRCLQRADGSVPDSEDEAGLVALLGRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q221</accession>
    <name>D3Q221_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2197</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017459.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41888">
        <property type="protein sequence ID" value="ADD41888"/>
        <property type="gene ID" value="Snas_2197"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2197"/>
    <dbReference type="eggNOG" id="ENOG502ZNCM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_933539_0_0_11"/>
    <dbReference type="OMA" id="IAYVMIR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="31296" checksum="5C636B12BDBB26B8" modified="2010-04-20" version="1">MTDNQQHYPDSSGARWETPAERPAFLDRTEPVSRQEREVRGGDSSLDDLMGNRNRTSRLPSQERGEEPSGVHAVPRGPESPPQQWSHDNAPAPAPQWSPENAPASPPQWSPDSAPTPPPQLGEPATGDPELAAVSRMDAPRQVPPPMPPQLGDNAHRPPMAQPSPPPADLNEPTQMHNPVTSAPPAQQQRGSTYPPQSGGVYQSNKSGLGSLAWVAALIMALPIAYVMIRSLASGADVILSGAVASGVFALAGLPLTAYGLQASLNANTGETPSPLRAPYVYLVIGLVLLLAAGMAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q234</accession>
    <name>D3Q234_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017472.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41901">
        <property type="protein sequence ID" value="ADD41901"/>
        <property type="gene ID" value="Snas_2210"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2210"/>
    <dbReference type="eggNOG" id="COG4803">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097445_1_0_11"/>
    <dbReference type="OMA" id="IGFEDPQ"/>
    <dbReference type="OrthoDB" id="2059684at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009200">
        <property type="entry name" value="DUF1269_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06897">
        <property type="entry name" value="DUF1269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="166" mass="16776" checksum="66732D582EBE95F8" modified="2010-04-20" version="1">MSTLVAVAYPDVSTAQTVLGKLGDMQTRQLITLEDAVVVEHRDNGKVKLHQTISTTGTGAVGGALWGGLIGLLFLAPLLGMAVGAGAGAAAGAATDVGVDDNFMKDLGNNLPAGSAALVLLVNQVTIDKVLAELGGQYGGRILQTSLSQEEEQHLREAAASAAANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q297</accession>
    <name>D3Q297_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4180"/>
    <dbReference type="EnsemblBacteria" id="ADD43830">
        <property type="protein sequence ID" value="ADD43830"/>
        <property type="gene ID" value="Snas_4180"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4180"/>
    <dbReference type="eggNOG" id="ENOG5032WFM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032560_1_0_11"/>
    <dbReference type="OMA" id="TQGGMLM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="589"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="612" mass="66457" checksum="B8DFFA0F130E822D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q331</accession>
    <name>D3Q331_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0283</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015572.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0283"/>
    <dbReference type="EnsemblBacteria" id="ADD40001">
        <property type="protein sequence ID" value="ADD40001"/>
        <property type="gene ID" value="Snas_0283"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0283"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_87_2_11"/>
    <dbReference type="OMA" id="AHRHDDH"/>
    <dbReference type="OrthoDB" id="1757088at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="3">
        <location>
            <begin position="150"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="246" mass="27027" checksum="435E3784E9D39C54" modified="2010-04-20" version="1">MPKIRHQPTAPTLARQLAPGDVIDAHRHDDHQIVYAARGVLAITTDKGSWIAPATRAIWVPAGTTHAHRAHGDLELHLVGLPARDNPLDLAEPTVLAIGPLTRELILAYTRSPADDSPERARLRAVLLDQLRATPQQPIHLPTPTDPRLSELCDRLRADPADNSTLTVLGRRVGASERTLSRLFKTELGMTFPQWRTQLRLYHALVLLADNASVTAVAHTCGWSSTSAFIDAFRRAFGHTPGAHQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q335</accession>
    <name>D3Q335_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">4-hydroxyphenylpyruvate dioxygenase</fullName>
            <ecNumber evidence="7">1.13.11.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0287</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4HPPD family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.27" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015576.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0287"/>
    <dbReference type="EnsemblBacteria" id="ADD40005">
        <property type="protein sequence ID" value="ADD40005"/>
        <property type="gene ID" value="Snas_0287"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0287"/>
    <dbReference type="eggNOG" id="COG3185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034004_1_1_11"/>
    <dbReference type="OMA" id="DPFPVKG"/>
    <dbReference type="OrthoDB" id="402639at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003868">
        <property type="term" value="F:4-hydroxyphenylpyruvate dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009072">
        <property type="term" value="P:aromatic amino acid family metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07250">
        <property type="entry name" value="HPPD_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08342">
        <property type="entry name" value="HPPD_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005956">
        <property type="entry name" value="4OHPhenylPyrv_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041735">
        <property type="entry name" value="4OHPhenylPyrv_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041736">
        <property type="entry name" value="4OHPhenylPyrv_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959">
        <property type="entry name" value="PTHR11959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009283">
        <property type="entry name" value="HPP_dOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01263">
        <property type="entry name" value="4HPPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="27"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="193"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR009283-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="392" mass="43763" checksum="91B06F22F4CACCE5" modified="2010-04-20" version="1">MVDTINEAQLVGAVEHDINADDFPIKGWDHIRFYVGNAKQAAHYYSTAFGMTLEAYRGPEQGFREHAEYMLRSGGVRFVLAGGITADSAATKHYAAHGDGVIEVALEVPNVDDNYAFAIKQGAVGVEEPHDLTDEYGTVRVAAIATYGETRHVLVDRSRYNGPFLPGYVAAKPIVDRTAAIKDGREPKRFFQALDHVVGNVEEGKMLDWVTFYQKVMGFTNIVEFVDDDIATEYSALMSKVVANGTRKVKFPINEPAEGRKKSQIDEYLEFYGGPGVQHMALATNDILASVDAMRANGVEFLDAPDSYYDDPEMRERIGTVRVPIEELKKRSILVDRDEDGYLLQIFTKPQQDRPSVFYELIERHGSLSFGKGNFKALFEAIEKEQAKRGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3A0</accession>
    <name>D3Q3A0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2252</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2252"/>
    <dbReference type="EnsemblBacteria" id="ADD41941">
        <property type="protein sequence ID" value="ADD41941"/>
        <property type="gene ID" value="Snas_2252"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2252"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="HHVGAMV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="3">
        <location>
            <begin position="182"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="156"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="386" mass="39869" checksum="62CB774BAF50B3B4" modified="2010-04-20" version="1">MRSDVWRRTAPDVAVATLAVGFGVVTTWRSWGHDGAPGWLSAGAVIGAGLAMAFARRLPVPVLGVLAVLLLVTDHYSPFAANPVQFLLLLGLGYVAFTCGWPTTIACYVVALVTTAVNLVDAGSGVSLTWWRVAGVLVVLAAPIAFGRYLAGLRAVAALNRARARETAERVQAEAAAARLAERARIARDLHDIVAHHVGAMVLRAGAAQYAGAPPPVAEALGDIRSTGTQVLEDLRGLLAVLRDPAAVEGAPSVSEPEAVMTEAVERSAAAGLRLSADIDPAAATAPMVVRATAARLVQEGLTNVLKHAGPGTDTRVTVTAATGTLTVEVVNDAPETSGPRPLPSTGYGLSGMRERVAMLDGHLEAGPTGTAGWRLSASIPYGSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3D5</accession>
    <name>D3Q3D5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2287</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017547.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2287"/>
    <dbReference type="EnsemblBacteria" id="ADD41976">
        <property type="protein sequence ID" value="ADD41976"/>
        <property type="gene ID" value="Snas_2287"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2287"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_81_0_11"/>
    <dbReference type="OMA" id="QYLQGWR"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032783">
        <property type="entry name" value="AraC_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12852">
        <property type="entry name" value="Cupin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="184"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="284" mass="31517" checksum="B6636E6092AF56BE" modified="2010-04-20" version="1">MAPVDRLTPLLERFRVRTRLFHTGPLCGVTTFAARPGRGFLHVLRHGEMDVTYQGTGGRLERTRIDRPSLLFYPRPLEHAFHNAPTADSDFACATLDFDGGQTHPLVRTLPPVIVLPLHVVDSLGPALDLLFAEIDNVRCGNPVLADRLFEVVLIQLFRWILDHTTELALPAGLLRGLSDDRLARTLVAIHESPGRPWTLTTMAREANLSRSTFAARFKATVGQPPADYLTAWRLTVAQDRLRHGATVSATAAELGYANSSAFSRVFTQRLGRSPRAWRATADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3T9</accession>
    <name>D3Q3T9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Dihydroxy-acid dehydratase</fullName>
            <shortName evidence="15">DAD</shortName>
            <ecNumber evidence="14 15">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ilvD</name>
        <name evidence="16" type="ordered locus">Snas_4359</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="15">Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13 15">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 15">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14 15"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4359"/>
    <dbReference type="EnsemblBacteria" id="ADD44006">
        <property type="protein sequence ID" value="ADD44006"/>
        <property type="gene ID" value="Snas_4359"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4359"/>
    <dbReference type="eggNOG" id="COG0129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014271_4_2_11"/>
    <dbReference type="OMA" id="TQGRNMA"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00057"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7 15" id="KW-0408">Iron</keyword>
    <keyword evidence="8 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 15 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="520"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="15">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="494"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="15">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ADD44006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="614" mass="64410" checksum="570B71D1244C907B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q423</accession>
    <name>D3Q423_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6288</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021479.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6288"/>
    <dbReference type="EnsemblBacteria" id="ADD45908">
        <property type="protein sequence ID" value="ADD45908"/>
        <property type="gene ID" value="Snas_6288"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6288"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_2_0_11"/>
    <dbReference type="OMA" id="QHELAVM"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="237" mass="26726" checksum="8840368B926A24D1" modified="2010-04-20" version="1">MSERLGLRERKKDATRHRLMQAALDLFEERGFDEVSVAEIADAAEVSKKTVFNYFDAKEDLILGHAKFQIEVPAQLVRERPPGQTPHDALRQQWFERLAEHHPVTGLSDNPGVLRVIRLIHSTPQLMQRQMRYGYQSQQLLSQELFAESGSELSARLMASQIFGVRQELAVANFRGITAGATAAERYPEAVKEAELGFDLLENGLGNLLRREELYQRIPGYQPCGLTLDIGPLAVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q483</accession>
    <name>D3Q483_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Natural resistance-associated macrophage protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6352</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021539.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6352"/>
    <dbReference type="EnsemblBacteria" id="ADD45968">
        <property type="protein sequence ID" value="ADD45968"/>
        <property type="gene ID" value="Snas_6352"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6352"/>
    <dbReference type="eggNOG" id="COG1914">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020088_6_3_11"/>
    <dbReference type="OMA" id="LRGYLVI"/>
    <dbReference type="OrthoDB" id="416257at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="PTHR11706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00447">
        <property type="entry name" value="NATRESASSCMP"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="241"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="289"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="419" mass="42819" checksum="ACCEE6B07EBE50DD" modified="2010-04-20" version="1">MSDRKIADASPATPTKRQRFGPGLLVTAAFIGPGTVTTASVAGAEFGFALVWAAVFAILATMVMQEMAARLGIVSRAGLGEALRATFTNPVTGVIVAVLVVAAIAVGNAAFQTGNIAGAAVALTTISGVPTQVWAVAVGVLAFGLLYTGIYRFIEAVMIALVGVMTIVFIVTAVVVRPDLGALAAGLVPTIPDGSTITVIALIGTTVVPYNLFLHASSVRQKWTADIPLEKSLPQARTDTYVSVGVGGVITLAVVTTAAASLFAHGLSVSNGADMAQQLEPLLGPAAKWFFAVGLFAAGLTSAITAPLAAAFAVSGMLGWRMDLKSWRFRGVWVAVLVIGAVLAVAVGESPVPAIIFAQTTNGLLLPIIAVFLLVVVNRKQVMGEHRNSLARNLAGGTVVLVATGLGVFNILKGLGVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4D9</accession>
    <name>D3Q4D9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0382</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40099">
        <property type="protein sequence ID" value="ADD40099"/>
        <property type="gene ID" value="Snas_0382"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0382"/>
    <dbReference type="eggNOG" id="ENOG5034415">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1524227_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="176" mass="17907" checksum="A26C48004D797944" modified="2010-04-20" version="1">MKKWYNSLSPGEQFGAVVGGTVGALIFLFAMCGFVGVLADSDGTNVSHVGASTSASASESPTASSPSASSKSPSPEPSTSSEKPSPKPSKSESPSPPPKPDLCGAPQNPYGYNYCGTGGVVHDPPGDICFYFECIDYFDEGKGYMVACDDGMVSMSGGRSGACSYHGGVGRTVYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4J9</accession>
    <name>D3Q4J9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0444</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015730.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40159">
        <property type="protein sequence ID" value="ADD40159"/>
        <property type="gene ID" value="Snas_0444"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0444"/>
    <dbReference type="HOGENOM" id="CLU_545017_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="292"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="478"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="320"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="500" mass="54163" checksum="0778BB4F7650135B" modified="2010-04-20" version="1">MNDAQGDGGGGGSAVGSELAKASKQIRRLATGREFEDEGYQFAWTDGDKDDYENPGWLESDWKQLTLDRYLAGPESNTKYGPANKGQNSTYYVVEGSEVYYYKYDKFAWVTDLLSEFGKGSPSGLHDICKSVKGVPPKLCAKGDWPKELDKFKREYSLKEIAGEEVLLDSGVSEMERWSGEAAATFVLAFGENLTKWEEALWGMYFLSEAVLAGVEAQTAIVIAARDDALTIAEKTANALVAVNHWSKDDLLVALGVAAAIIPAALSFGGFALTATIIGAGIGLSNTMVSNSDSTGVSVPESEKKHTKRTMNGDSPADILDRFRTEIGTIREEASTQEEELANKLERVYNSSLDIRTEKLEITYPDGSKSPADSGLGKRETKAHTSYLKDAAVTSFPQAASYVLGARDEVARTAGLDSDTTFHSEHRDSVSPAAEPWRLVRDLLQDITAANGKKVEDAGEVIFKAAVDMELVDGEEAANIEKTYDDLGTGESGRKHKAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4N2</accession>
    <name>D3Q4N2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M43 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017633.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2377"/>
    <dbReference type="MEROPS" id="M43.009"/>
    <dbReference type="EnsemblBacteria" id="ADD42062">
        <property type="protein sequence ID" value="ADD42062"/>
        <property type="gene ID" value="Snas_2377"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2377"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011684_0_0_11"/>
    <dbReference type="OMA" id="QRYLNIW"/>
    <dbReference type="OrthoDB" id="1063831at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04275">
        <property type="entry name" value="ZnMc_pappalysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M43" evidence="2">
        <location>
            <begin position="153"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="311" mass="34059" checksum="C4F7DB78B10342D5" modified="2010-04-20" version="1">MYEPNTLTPGTNWCASMSVHHRLLDTDSDYATARRDIEDSAFEWIRSRRARRDNVITIPVVVHVVWHDRSENISNGQIHSQIEVLNNDFRKKNKDIDTVPKVWQDITADVGLEFALATHDPQGIATTGINRVETRAESFGAEDDVKSSATGGADAWPADRYLNIWVCRLRGGLLGYAQFPGGPPATDGVVITHRGFGANGTATAPFDQGRTCVHEIGHWLNLRHIWGDDGEGCSGDDFVDDTPNQGGPSSGVPLYPSVSCDNGPHGDMFMNFMDYSNDAVTVMFTQGQAARMDACLESARSSFLEPEATAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4R0</accession>
    <name>D3Q4R0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphatidylinositol alpha-mannosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.57</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2407</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.57" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2407"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42090">
        <property type="protein sequence ID" value="ADD42090"/>
        <property type="gene ID" value="Snas_2407"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2407"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_1_11"/>
    <dbReference type="OMA" id="VCPYSWD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="3">
        <location>
            <begin position="17"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="385" mass="40688" checksum="D0DBB877DD2B864B" modified="2010-04-20" version="1">MAMKIGIVSPYSFAHPGGVQGHIRDLAETLIETGHEVSVLAPGDRDEEVPSYVVSAGRAIPVKYNGSVARLSFGPLAATRVRRWLRRNDFDVLHVHEPLSPSLSLLACVLARSPVVATFHTAMPRSRALAAGRGIAQLVLEKITARIAVSAHARRLQVEHLGGGATEIPNGVKVSRFAEAPPLPGWPGDGGCLGFVGRFDEPRKGFAILLDAFAALVPEHPGLRLLVLGPGDTDKAVAGLDPEVRGRIDFLGMASDEVKARMLRSVDIYVAPNTGGESFGMILTEAMAAGTPIVASDLNAFRRVLDDGAAGALFPVGDADALAETIAKLLPDNELKKSYVAKADELLPDFDWSNVAERVLEVYTAAVEATGGTAARETPPAPVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4S1</accession>
    <name>D3Q4S1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glucose-6-P dehydrogenase subunit-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2418</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017672.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2418"/>
    <dbReference type="EnsemblBacteria" id="ADD42101">
        <property type="protein sequence ID" value="ADD42101"/>
        <property type="gene ID" value="Snas_2418"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2418"/>
    <dbReference type="eggNOG" id="COG3429">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046988_1_0_11"/>
    <dbReference type="OMA" id="GDTDLSW"/>
    <dbReference type="OrthoDB" id="1406083at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004555">
        <property type="entry name" value="G6PDH_assembly_OpcA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38658">
        <property type="entry name" value="PTHR38658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10128">
        <property type="entry name" value="OpcA_G6PD_assem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="318" mass="34030" checksum="6E44E257801D080D" modified="2010-04-20" version="1">MIALWDTTATDVAAALHSERQSSGGTSGLALNLVVIVDEKDEREAEAALTVASQQHPCRLLIVLRRDLERDEPRLDAEIVVGGRLGPCEAIVMRMHGPLSQHAESVVMPLLAPDVPVVTCWLVPPPQVTGADPLGAFAERRITYAALAADPVEALRVRACDYTPGDTDISWTRITYWRSLIASAFDTATAPAKSVTITASAADPSAALLAGWLGSRLGVTPTIQDTEVERNSEHLPGIGGVSFTLENGDEIAIDRDRAGTTVLRRTGFPDRTQTINGRTLGELLAEELRHLDPDQPYQAALGTCTGEDRLCGADVVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4T7</accession>
    <name>D3Q4T7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Na+/solute symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_2434</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2434"/>
    <dbReference type="EnsemblBacteria" id="ADD42117">
        <property type="protein sequence ID" value="ADD42117"/>
        <property type="gene ID" value="Snas_2434"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2434"/>
    <dbReference type="eggNOG" id="COG0591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018808_15_0_11"/>
    <dbReference type="OMA" id="IYSIGTM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="485"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="517" mass="54197" checksum="4583BEED1FB7F3EC" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-08-10" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q557</accession>
    <name>PSB_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Proteasome subunit beta</fullName>
            <ecNumber evidence="1">3.4.25.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">20S proteasome beta subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Proteasome core protein PrcB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">prcB</name>
        <name type="ordered locus">Snas_4461</name>
    </gene>
    <organism>
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein degradation; proteasomal Pup-dependent pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019677.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D3Q557"/>
    <dbReference type="SMR" id="D3Q557"/>
    <dbReference type="STRING" id="446470.Snas_4461"/>
    <dbReference type="MEROPS" id="T01.005"/>
    <dbReference type="EnsemblBacteria" id="ADD44106">
        <property type="protein sequence ID" value="ADD44106"/>
        <property type="gene ID" value="Snas_4461"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4461"/>
    <dbReference type="eggNOG" id="COG0638">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_2_0_11"/>
    <dbReference type="OMA" id="NLGMAMQ"/>
    <dbReference type="OrthoDB" id="1129370at2"/>
    <dbReference type="UniPathway" id="UPA00997"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019941">
        <property type="term" value="P:modification-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02113_B">
        <property type="entry name" value="Proteasome_B_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022483">
        <property type="entry name" value="PSB_actinobac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03690">
        <property type="entry name" value="20S_bact_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-0647">Proteasome</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0888">Threonine protease</keyword>
    <keyword id="KW-0865">Zymogen</keyword>
    <feature type="propeptide" id="PRO_0000397582" description="Removed in mature form; by autocatalysis" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000397583" description="Proteasome subunit beta">
        <location>
            <begin position="54"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02113"/>
        </source>
    </evidence>
    <sequence length="279" mass="29238" checksum="88B353FE5EF90906" modified="2010-04-20" version="1" precursor="true">MSGTAEFPGRIPAPYLEVGSSSFVELLGSVAPELLPGRRPLPPGDMGDAAPHGTTIVALRCNEGVVMAGDRRATQGNMISLRDIQKVFPADAYSLIGIAGTAGLGVEMIRLFQAELEHFEKLEGNALSLHGKANKLANMIRGNLGIAMQGLAVLPLFAGFDTDAPDAASAGRIFSYDVVGGIYEEREYDAIGSGSIFAKSALKKRFQSEVDATEATRLAIEALYDAADDDSATGGPDLTRKLFPTVFTATADGAKRVPDAEIEAVSRAVVAARLENPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q572</accession>
    <name>D3Q572_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RecB family exonuclease-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019692.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4476"/>
    <dbReference type="EnsemblBacteria" id="ADD44121">
        <property type="protein sequence ID" value="ADD44121"/>
        <property type="gene ID" value="Snas_4476"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4476"/>
    <dbReference type="eggNOG" id="COG2887">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049030_0_0_11"/>
    <dbReference type="OMA" id="LCGWCDH"/>
    <dbReference type="OrthoDB" id="1283891at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038726">
        <property type="entry name" value="PDDEXK_AddAB-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12705">
        <property type="entry name" value="PDDEXK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDDEXK_1" evidence="1">
        <location>
            <begin position="10"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="267" mass="29881" checksum="C5C094F83E1DAD10" modified="2010-04-20" version="1">MSSEFRAPVTLSPSRANDFKSCPLKYRYRVIDKLPEPTSSAQVKGTLVHSVLERLYDLGAAERTSGRALELVEPEWKRLRDADAEAAGVVDDESAWIAEVRKLVEAYFAVEDPRRLQPAERECLVEATTADGVRLKGYIDRLDVAPTGEIRVVDYKTGGVPREAFRAEALFQLKFYAVALWHVRGVVPTVLRLIYLKDGQAIDYSPTEAELRATERNITALWRAIGEAVTRGDFRAKKSGLCGWCHFKDRCPEFGGTPPPYPLPITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q581</accession>
    <name>D3Q581_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphodiesterase/alkaline phosphatase D-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4485"/>
    <dbReference type="EnsemblBacteria" id="ADD44130">
        <property type="protein sequence ID" value="ADD44130"/>
        <property type="gene ID" value="Snas_4485"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4485"/>
    <dbReference type="eggNOG" id="COG3540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_603957_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD" evidence="1">
        <location>
            <begin position="99"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="453" mass="49567" checksum="1D278E8C2585ED1A" modified="2010-04-20" version="1">MSLSYTWVGATTPAAVIVKARLSGDTARLHVSTESDLADPVKSEAVAPENGVAELKVDGLKAATRYYYGVEIDGDLDREALGRFRTHPVLGEPADFTVAATSCAGFEPEHPGTGDVTVPARVSNHPVFSDIRERDPLMLLHMGDIHYYDIGSGEFVPDHDVDTYRGAFDDVFAQPRQAGLYRDVATQYVWDDHDFGPNNSDGTAPGRKAAAQVYRERVPHYELSDEVGIWHSWTIGRVLFVALDVRSYRSPDDDPDGPDKTMLGAAQKAWLKGVLESSDAAFLVLLPVCRWFDSSSNDTWSSFAEERSQLIDMFDSLGWAGRMCLVVGDLHAVAMDSGGNSPGRVPVFHFASMDSRPSVVNNHYDLGPSLPGRGQYGLLRLNDTGAEITVTATGYQGAEKIKSHSFTVGVSGTGHTCTPEEEMKEKRAKTEATSRPSLWTRLKQTVRGLFYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q591</accession>
    <name>D3Q591_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4495</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019711.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4495"/>
    <dbReference type="EnsemblBacteria" id="ADD44140">
        <property type="protein sequence ID" value="ADD44140"/>
        <property type="gene ID" value="Snas_4495"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4495"/>
    <dbReference type="eggNOG" id="COG1509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032161_3_0_11"/>
    <dbReference type="OMA" id="WAQFVGD"/>
    <dbReference type="OrthoDB" id="557227at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003739">
        <property type="entry name" value="Lys_aminomutase/Glu_NH3_mut"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30538">
        <property type="entry name" value="PTHR30538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01070">
        <property type="entry name" value="PLP-dependent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="432" mass="48938" checksum="5F9C38A3CA15C2D9" modified="2010-04-20" version="1">MSAPTSESEGRRFRAYTARHLEELLTRAGLSPEQRLRARAVATVLPFRTNDYVIDELIDWDAAPDDPIYRLVFPQEDMLPAEDVSKLAKLLDADPKGPELKAEVFAIRRRLNPHPAGQLDLNKPKLGEADIPGMQHKYPETVLFFPQQGQTCHAYCTYCFRWAQFVGESDLKMASNDIDALVGYIKAHPEITSVLITGGDAMIMGAPVLRRYIEPLIQLEQLESIRMGTKALAYWPQRFVTDPDADDTLRLFEEVCESGKNLAFQAHFSHTRELAPTMLHDAVKRIRDTGAVIRTQAPLIKSINDDPQVWSDMWRKHHTMGMVPYYMFVERDTGPQEYFAVPLARAYDIFQEAYSQVSGLCRTVRGPSMSADPGKVAVDGVVEINGTRVFVLHMIQARDPKLVGKPFFAHYDPDAVWLNDLKPAFAERFPFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5A1</accession>
    <name>D3Q5A1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH_hydro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019721.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4505"/>
    <dbReference type="EnsemblBacteria" id="ADD44150">
        <property type="protein sequence ID" value="ADD44150"/>
        <property type="gene ID" value="Snas_4505"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4505"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038449_4_1_11"/>
    <dbReference type="OMA" id="EDSRWIE"/>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01823">
        <property type="entry name" value="SEST_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037460">
        <property type="entry name" value="SEST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981">
        <property type="entry name" value="PTHR37981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049703" description="SGNH_hydro domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="37"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="297" mass="30671" checksum="3560044B62A95DFE" modified="2010-04-20" version="1">MPSPNLRRILAVSTVAAAAVALLSTPAHAVDTSRYVALGDSFTSGPLNTLPVGEPIGCFRSGKNYPSVVSEQLDVAEFTDVSCGGATTEHMLNPQNTPIGTNNPQLDALSADTTLVTLGIGGNDIGFGFGEIILACVSGGALDPFGTPCQDKYVNDGKDELRERIAATRSKVDAVLDQIATRSPEATVVVVGYPAVLPAEKGCWPKVTIAKKDVPYLDSVQQDLNAMLGEAASAAGALYAVNYERGHDVCSDRSDRWVEGIIPTKPAAPVHPNADGSAAMAGPVIDLVGDGVTSPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5B6</accession>
    <name>D3Q5B6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_4520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4520"/>
    <dbReference type="EnsemblBacteria" id="ADD44165">
        <property type="protein sequence ID" value="ADD44165"/>
        <property type="gene ID" value="Snas_4520"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4520"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_3_11"/>
    <dbReference type="OMA" id="IVRELCH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="58"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="120"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="344" mass="36752" checksum="B9C66FC9DD10D63E" modified="2010-04-20" version="1">MTWPVRPTLRLRLALWMGGAALVVGLVAVLVAPVLRFELATVVVAAMVCFVVGYVVAGRSLRPLHEVTATAKRLSTDTLDDERIRLDGPPDEVRELADTFDDMLDRISASFEAQRRFVSNASHELRTPLTVMRTEIDVALSNPDDDIAELRQMGEVVRDGCDRVNDLIESLLWLARAEAEGQGGLSKAQLTDLGDCAEAMMATARRAADIMELSLAVSRLPAPVVGDPALLERVAGNLIENAIRHNNPGGRVWVLTGGDREISWLVVGNTGADVDAASVPRLFEPFSRGGDARVGRRGAGLGMSIVRAVCRAHGGSVSARALPEGGGLEVRVELPAAEVTVEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5P8</accession>
    <name>D3Q5P8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015768.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0482"/>
    <dbReference type="EnsemblBacteria" id="ADD40197">
        <property type="protein sequence ID" value="ADD40197"/>
        <property type="gene ID" value="Snas_0482"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0482"/>
    <dbReference type="eggNOG" id="ENOG503498K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151322_1_0_11"/>
    <dbReference type="OMA" id="PKGINTE"/>
    <dbReference type="OrthoDB" id="2098190at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="89" mass="9372" checksum="5F30D9E67DEC4BBF" modified="2010-04-20" version="1">MRDIPFLIALQAETINTKGIIDFFLSKIAPILLAILGIIFIARANKGEVSKVLTSSTIAIVGLAFIAGAVTLVLVGTSLVDILFTDEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q685</accession>
    <name>D3Q685_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Oxygen sensor histidine kinase NreB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nitrogen regulation protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Snas_2580</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017831.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2580"/>
    <dbReference type="EnsemblBacteria" id="ADD42260">
        <property type="protein sequence ID" value="ADD42260"/>
        <property type="gene ID" value="Snas_2580"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2580"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_15_11"/>
    <dbReference type="OMA" id="WSATHEL"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017205">
        <property type="entry name" value="Sig_transdc_His_kinase_ChrS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037434">
        <property type="entry name" value="STHK_ChrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="14">
        <location>
            <begin position="331"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="192"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD42260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="422" mass="45232" checksum="C0DD3264E5A06FE6" modified="2010-04-20" version="1">MTTPHGPRPVSASAGRLAGPGTAPGGDPEPLEHRWNRIWALLPFALLAPASVIAALDTTGWIARGLILALAVALAGWHIWWILCNPQWPEQSLAHMAVYFLGAIALLAALRSRDEVFVIAVSGFFPMAFVALPGAWAYPGVVLLSLLTVPEAPRGLWQGLTLGDLLFPTVGVAVASFIGAMMRTVEREAIRRREVNARLVALADENAALQARLVEQARQAGVTAERARLARDMHDTVAQGLAGIVTQLETAEADPDDTARRLRIARDLARDSLVEVRRSVAALRPALLDDADLAEALAREVDAWRHRNDIAATFTVTGTPVPLDAAVDEAVLRVAQEALSNTARHAKASRLGVTLSYMEDMLVLDIRDDGEGFAVDAEPRQGFGLTAMRQRVEQLDGSVHIESKPGAGTAVSVSLPLDGDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6U5</accession>
    <name>D3Q6U5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015915.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0630"/>
    <dbReference type="EnsemblBacteria" id="ADD40344">
        <property type="protein sequence ID" value="ADD40344"/>
        <property type="gene ID" value="Snas_0630"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0630"/>
    <dbReference type="eggNOG" id="ENOG503428B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_857676_0_0_11"/>
    <dbReference type="OrthoDB" id="1639867at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="48"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="324" mass="35141" checksum="92EB4334E545757A" modified="2010-04-20" version="1">MSEFDTVKTQLHQARSTINDAVAITQQAYSSTDDKKSRLEQLGVAATAQALDLALEKLREALEQLASARGETDKAAETLDKVPDTAPIPDVIAILGTTVSTLGTTKISIDTSGESVKGAMEQAQLAGTEGIVNLCHDASSTIDGARQGAQTAINAVNGYQKRLETEAQELEGLSSEASQPRANPTPMSTPQATVSSSRGRTQVSKPHPAADGRATFGTSTSRNYKKTFFDKHPDTEGKVVVHHAVEQKTLKLYQGAVTESEMHSYENLRGIPKGETNNRVHLSAIRMSWNEFYRDNPSPTKQQLLDHATKVDNEYGHQFNPPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6X0</accession>
    <name>D3Q6X0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic binding protein/LacI transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015940.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0656"/>
    <dbReference type="EnsemblBacteria" id="ADD40369">
        <property type="protein sequence ID" value="ADD40369"/>
        <property type="gene ID" value="Snas_0656"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0656"/>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_3_5_11"/>
    <dbReference type="OMA" id="DNIELRY"/>
    <dbReference type="OrthoDB" id="1378040at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048914" evidence="1">
        <location>
            <begin position="30"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="45"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="34284" checksum="9F785256341146F2" modified="2010-04-20" version="1">MKTPLRSGLILAIVATSALALSACSSSGGKQDEGKGADTPRQTIALITHSAKGDTFWDIVREGAEAAAAKDNIELKYYSDPEGAGQAKLIRNAVDQKVDGIAVTLAKPDAVASAVEKATDAGIPVVGLNSGIDHWQDLGVLEYFGNDETIAGTAFGEQLNEVGAKKTLCVIHESGQVAQEARCKALKEEFKGKTEIQYVDGGNMPDVKSSLTSKLQSDKKIDFVSTLAAPIATTAVEAVADADSKAKVATFDTNKELVKAIKNGDIQWAIDQQPYLQGYLAVDGLWLYNTNGNTSGGGSQPVLTGPAIVDKSNVDDISKWAENGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Z8</accession>
    <name>D3Q6Z8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 3">Nucleoside diphosphate kinase</fullName>
            <shortName evidence="1">NDK</shortName>
            <shortName evidence="1">NDP kinase</shortName>
            <ecNumber evidence="1 3">2.7.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Nucleoside-2-P kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ndk</name>
        <name evidence="5" type="ordered locus">Snas_0684</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:18113"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NDK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="1 3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0684"/>
    <dbReference type="EnsemblBacteria" id="ADD40397">
        <property type="protein sequence ID" value="ADD40397"/>
        <property type="gene ID" value="Snas_0684"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0684"/>
    <dbReference type="eggNOG" id="COG0105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060216_6_3_11"/>
    <dbReference type="OMA" id="KIVAMKM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006165">
        <property type="term" value="P:nucleoside diphosphate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="SSF54919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDP_KINASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NDK" evidence="4">
        <location>
            <begin position="2"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="1">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="135" mass="14792" checksum="1CA6D266839F84DE" modified="2010-04-20" version="1">MSQRTLVLVKPDAVRRGLVGEIVSRLENKGLTIEEMQTRTMDGELADTHYAEHVDKPFYPPLKDFMTSGKLVALIVSGDEAITVVRSLAGATDGRKAAPGTIRGDLSLSNRENLIHASDSEDSAKREIALWFPDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q783</accession>
    <name>D3Q783_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2677</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2677"/>
    <dbReference type="EnsemblBacteria" id="ADD42354">
        <property type="protein sequence ID" value="ADD42354"/>
        <property type="gene ID" value="Snas_2677"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2677"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_25_3_11"/>
    <dbReference type="OMA" id="MANGENI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16859">
        <property type="entry name" value="TetR_C_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="18"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="23004" checksum="05481E785CC7312D" modified="2010-04-20" version="1">MTEGSDELTEPAKRRRGKELEAAILAAAWEELLEVGYSGFHIENVAARAQTGKAVLYRRWSSRAELVLAVVSSRAPDKDEVPNTGDLRTDVIALMTWMAGRLLPVGRDVTLGLVSEVYRNPELSERLRALIVETFQHRTMGPIIDRAVERGQVDRDRVTLRVVTLPIDLMRNDMLLYGTASEDSITEIVDQIFLPVIGYRGRTDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7F6</accession>
    <name>D3Q7F6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2751</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017998.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2751"/>
    <dbReference type="EnsemblBacteria" id="ADD42427">
        <property type="protein sequence ID" value="ADD42427"/>
        <property type="gene ID" value="Snas_2751"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2751"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_1_2_11"/>
    <dbReference type="OMA" id="LFDSGYC"/>
    <dbReference type="OrthoDB" id="1650683at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="272" mass="29439" checksum="EF1ACB4C90CC4A83" modified="2010-04-20" version="1">MTEPGTLLVGCVQMRSDLDPGENLRQCLRYLDEARTAGVDLLIFPETVSSRVDDPSRAPQAESLDDGFVAGLAKATEGLDLTVIAGVTETHDDRPFNTLVALRDGQRVARYRKIHLYDACAMAESDTIAPGDGPVSTFAVKGFEVGMMTCYDIRFPELSRLLAERGADLLAVPTSWVRGPLKEEHWTTFCKARALENTVYLAGACQTGGSRVGLTSVVAPDGVIVSRLAQHEGLVTARIGRDALTAAREAFPLLEQRRFAISPEITPHPTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7K8</accession>
    <name>D3Q7K8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4707"/>
    <dbReference type="EnsemblBacteria" id="ADD44350">
        <property type="protein sequence ID" value="ADD44350"/>
        <property type="gene ID" value="Snas_4707"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4707"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_915009_0_0_11"/>
    <dbReference type="OMA" id="FKAPYPC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048719" evidence="1">
        <location>
            <begin position="30"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="67"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="294" mass="30772" checksum="1E96832033949D70" modified="2010-04-20" version="1">MWKKRIALAAAAMLTAAIASVLAAPSAQADPSVNAMPNFQLPFPCGQTWNGDNDNSSAHRAWEIDFNRGSSASADLKDTVVAAAAGTIETAAHQGSANGYGNLVKIRHDSTGYYTYYAHLNNLAVKAGEYVSQGQVIGTLGNTSKPGNAISPHLHYEVRVDGSYPGNIRKAVFNGATFGYPNANVTSRNCANTYDPADLCGSGYYQIDSARLGGKGTVDLAWNGSANCVVTRKFTSLGTATATSAYLEPQGATRATDSGNFTHYAGPVRATSPSCVRWGGAVEGTAYNSPSEHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7M4</accession>
    <name>D3Q7M4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Activator of Hsp90 ATPase 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019937.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4724"/>
    <dbReference type="EnsemblBacteria" id="ADD44366">
        <property type="protein sequence ID" value="ADD44366"/>
        <property type="gene ID" value="Snas_4724"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4724"/>
    <dbReference type="eggNOG" id="COG3832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108923_2_0_11"/>
    <dbReference type="OMA" id="LARWYAF"/>
    <dbReference type="OrthoDB" id="1914312at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="135" mass="14619" checksum="5F1A3E304F52B8E4" modified="2010-04-20" version="1">MAEAPVTVITEELLIPATADALWPLVSTGAALARWYAFGGAEIDARPGGAMVLRWDEHGSFPATVERVEPGRLLSFRWQPEGDPLVEIRLEPEAEATRVTITESGRLDNPELDAGAWRNSLGLLRDLATGLDQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7S8</accession>
    <name>D3Q7S8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019991.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4779"/>
    <dbReference type="EnsemblBacteria" id="ADD44420">
        <property type="protein sequence ID" value="ADD44420"/>
        <property type="gene ID" value="Snas_4779"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4779"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057148_1_0_11"/>
    <dbReference type="OMA" id="WWGGMWA"/>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="40"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="264" mass="29148" checksum="2B8A9482B06984E5" modified="2010-04-20" version="1">MTAVYTHGHHTSVLRSHRWRTAENSAAYLLDHLAPTQRLLDVGCGPGTITADLAARVAAVTAVDTSASVLAEARAFGDDRQLTNVDYQVADVHSLPFDDDTFDVVHAHQVLQHVADPIAALREMRRVCRPGGIVAARDADYEAMTWYPAIPELDEWLDLYRRVARDNHGEPDAGRRLLAWAHEAGFETVTPSADVWCYATPTDREWWSGMWAERITSSGIATTSVDNGHASPADLQRLSQGWQRWGAEADAWFTVLHGEIVAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7U7</accession>
    <name>D3Q7U7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016023.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0740"/>
    <dbReference type="EnsemblBacteria" id="ADD40452">
        <property type="protein sequence ID" value="ADD40452"/>
        <property type="gene ID" value="Snas_0740"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0740"/>
    <dbReference type="eggNOG" id="ENOG502ZBFQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_965182_0_0_11"/>
    <dbReference type="OMA" id="GGHDTWD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="304" mass="33554" checksum="85F0D7DAAB5EDDD2" modified="2010-04-20" version="1">MAKDKKAPEEDDTSSETETTEADNDTDELDADDTPQRTAKADAFWEKVGVEPVEIALPKGVGLTLRAYRMSDAVEDGEEEPEAEADEDEKPVKADKKDKAKAKDKKKDDEDDEEIDDSEESETDSDDEADEKDSDEEPEAAEPEEIPIFLTLNGKLPLFESAEALVEFVKSGAPTDLEAIDTWDELVKGIKVDYVVPAEDDSYELDLVVKNLRGGHDSWDPELMIGAGELARDLGYALRLPTVMSTLAVGSPLDGLDNHLRSVVDGGLKAMFAKRKIRKIGTQQTALAWRGIVNKINETVDWRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7X5</accession>
    <name>D3Q7X5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016051.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40480">
        <property type="protein sequence ID" value="ADD40480"/>
        <property type="gene ID" value="Snas_0768"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0768"/>
    <dbReference type="eggNOG" id="ENOG502ZZXN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1260814_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="22774" checksum="8461F69D02152724" modified="2010-04-20" version="1">MSTNPSVPRNRRLWSWGGAGFAALFLGGQFASAPLENGSIPLPDAPVAEVVEYFSANTATSAVLGTANVLAGLALLFLVGRAALGMRSPGGRVGVVAGWIAGLSLAVSGTLSVVLGQVAATAAPGTVETLRDWNFWTGGVIHVVCLGLFVGLLCLPSVTEPMTGRGVRIFGLVASVPAVLSISSLLWFYASALLPLGRFSLIVWAVFAAVSLWRNPKPNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q812</accession>
    <name>D3Q812_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">N5-carboxyaminoimidazole ribonucleotide synthase</fullName>
            <shortName evidence="3 5">N5-CAIR synthase</shortName>
            <ecNumber evidence="3 5">6.3.4.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 5">5-(carboxyamino)imidazole ribonucleotide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">purK</name>
        <name evidence="7" type="ordered locus">Snas_0805</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19317"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the PurK/PurT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.18" evidence="3 5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016088.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0805"/>
    <dbReference type="EnsemblBacteria" id="ADD40517">
        <property type="protein sequence ID" value="ADD40517"/>
        <property type="gene ID" value="Snas_0805"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0805"/>
    <dbReference type="eggNOG" id="COG0026">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011534_0_2_11"/>
    <dbReference type="OMA" id="ITFDHEH"/>
    <dbReference type="OrthoDB" id="1165275at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034028">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="111"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="176"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="261"/>
            <end position="262"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="384" mass="40797" checksum="36A61C3C853F8AF4" modified="2010-04-20" version="1">MDSRTQLPVVGMVGGGQLARMTHQAAISLGQSLRVLAASADDGAAIVSTDVHVGSHTDVEALRGFAKECDVLTFDHEHVPGDLLRTLRSEGVVVRPAPEALRYAQDKQAMREHLGGLGLPVPRWAPIDSVAALADFGVPCVVKTATGGYDGKGVFYVDAPEQITELLDAGAVLIAEERVRLRRELAALVAGSPGGELASYPIVETVQRDGICTEVIAPAPGLSEVLAEQARELARRVATELGVTGLLAVELFETDDGLVVNELAMRPHNSGHWTIEGARTSQFEQHLRAVLDYPLGETAPTAPVTVMANVLGGAPGGSRLDERLQSMLADDPGARVHLYGKQVRPGRKIGHVTVLGDDVETVRRRARRAAAWLRDGDPEAGEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8D9</accession>
    <name>D3Q8D9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018084.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2837"/>
    <dbReference type="EnsemblBacteria" id="ADD42513">
        <property type="protein sequence ID" value="ADD42513"/>
        <property type="gene ID" value="Snas_2837"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2837"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_782814_0_0_11"/>
    <dbReference type="OrthoDB" id="1456605at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="354" mass="38508" checksum="67838F4B95A4A1F9" modified="2010-04-20" version="1">MTTRFRDDLVHMASEVRDADLAARARAGSRRRRNRNVLIGCAVLLVAAPLAVVGATSFAERREDAAEFGDFDGTFVYLRDDTEDDGAAELVRRDGTEESTVLSVPSSDITGDISVSADGEWAAWERQGNGDTDIMVADLSTGDTKKLLSHSSNSCVAPTWAPDGAPLLLTPDPDSSTGAVRWNNVESEESTAPLETITERADALCPTFPVARSDGDYDLYYSTGEPFRLRYLAPDGSFHDVEGVGKLRDAAGDYWADIAGVSRDGDRVCLTAPHEDDDVSFPRCDAVVDPGSGKVLRDRRKDPATQVLFLPNGESISRNADGVMERCDADGEVVARTQEDSRWRDHRLMAYVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8P9</accession>
    <name>D3Q8P9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lipolytic protein G-D-S-L family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4850</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020062.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4850"/>
    <dbReference type="EnsemblBacteria" id="ADD44491">
        <property type="protein sequence ID" value="ADD44491"/>
        <property type="gene ID" value="Snas_4850"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4850"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044083_4_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048947" evidence="2">
        <location>
            <begin position="24"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="3">
        <location>
            <begin position="49"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="253" mass="27458" checksum="7869D19DB00C3C09" modified="2010-04-20" version="1">MRRWARAVVPLLALVLVAAVSLATVGRDVSNDAERMNPASDRSITVMPMGDSITGSTGCWRALLWAKLRGTGHKNVDFTGNGIGPECDSIFDDDAVAYSGTRVVDMKPDSTFLKTLRTTGKSARIALMHLGSNDIRDDKSIEEILDGYTTIAGLLRQANPDIVILVAQLIPITTSPMDKDCPQCPGKVEELNEAIPGWAKDMDRKSSPITVVDQHDGFDPGDDTYDGLHPDDSGGRKMADKWFEAIDEVVGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Q1</accession>
    <name>D3Q8Q1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4852</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4852"/>
    <dbReference type="EnsemblBacteria" id="ADD44493">
        <property type="protein sequence ID" value="ADD44493"/>
        <property type="gene ID" value="Snas_4852"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4852"/>
    <dbReference type="eggNOG" id="COG1119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_11"/>
    <dbReference type="OMA" id="HVLMIRQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="31"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="63"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="286" mass="30650" checksum="81EDB2A5DAA1D6A3" modified="2010-04-20" version="1">MTAVTTTGPLLKLPCDRDSIQCVSSTSDLVIDVSDVVVRRGASVLLDHVDWQVELDERWVILGPNGAGKTTLLNLVSGRSHPTKGTVRVLDEQMGKVDVFELRPRIGLASAALAETIPGDEPVADAVVTAAWAVLGRGRESYEAMDEIRARGLLEQFGIDTLADRRYATLSEGERKRVQIARALMTDPELLLLDEPAAGLDLGAREALVGRLGELAMDPDAPALVLVTHHVEEIPPGFTHALLLTEGAVVASGLLDDVLTAQNLSKTFGLPLRLERDGGRFTARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8R1</accession>
    <name>D3Q8R1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4862"/>
    <dbReference type="EnsemblBacteria" id="ADD44503">
        <property type="protein sequence ID" value="ADD44503"/>
        <property type="gene ID" value="Snas_4862"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4862"/>
    <dbReference type="HOGENOM" id="CLU_134369_3_0_11"/>
    <dbReference type="OMA" id="MWADAAS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="141" mass="14550" checksum="0F1BC63D723BE753" modified="2010-04-20" version="1">MNTVNIARPADSAVSVKSDRFLRLVLRLDAVATLGSGALMAAGGGLLAEPTGIPAGAAHGIGAFLVVYALAVGVLSFRPVINRAAAWTVVGLNTLWVIDSVATLVAGFWELTAMGTGFIIVMAVVVAAFAELQYVGIRRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8W1</accession>
    <name>D3Q8W1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerophosphoryl diester phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0859</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0859"/>
    <dbReference type="EnsemblBacteria" id="ADD40570">
        <property type="protein sequence ID" value="ADD40570"/>
        <property type="gene ID" value="Snas_0859"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0859"/>
    <dbReference type="eggNOG" id="COG0584">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030226_0_1_11"/>
    <dbReference type="OMA" id="CRHENDI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049654" evidence="1">
        <location>
            <begin position="28"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="2">
        <location>
            <begin position="40"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="356" mass="39762" checksum="B48E7642A0140D4B" modified="2010-04-20" version="1">MRRKLVATAAAVGVLAGCLALAPSANAEPAKDKKSAACDVMVTGHRGASGYRPEHTIEAYTVAVTLGADYFEPDLVPTKDGQLVARHESEISQTTNVADKPEFASRKTTKVIDGVSYTGWFTEDFTLKELKTLRAKERLPELRPYNKDHDGLYPIMTIEEIIKLRKDLSFQNKREVGIYPELKHPTYFNSIGLKVEELLDQKLGAADLDDADDPVLIQSFEEGALKKMDSLVDNKLVFVIGDKAATPDKLKEYAKWLHAVSYAKDIIIPRKSDGSLGTPSTAVKDAHTAGLDVHSWTFRNENFFLPTNLRIGDYPPDWGNYQEEYRLFINTGIDQMFSDFPDKAIDAREECSKKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8X7</accession>
    <name>D3Q8X7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016157.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0875"/>
    <dbReference type="EnsemblBacteria" id="ADD40586">
        <property type="protein sequence ID" value="ADD40586"/>
        <property type="gene ID" value="Snas_0875"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0875"/>
    <dbReference type="HOGENOM" id="CLU_562465_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="485" mass="52361" checksum="D7B17F54BC19C7C5" modified="2010-04-20" version="1">MNGYYDRFTGLNLDEILEITGTDSAHSDELRRQGAGLKALSDKLDESIGAMASANNGVESTFDGASARALMESMLTLMRRGSEGHQALRAQPDVFFNLSAESNATHRHMLALREEREDWLDRWRRNPADPKVLAKFGGKAGADGMYHAIRDEYDVEARQFMRRTTGGYVDSVKSLQSMQPYDGPRLPREDEANGPRGFRDLTTAGPSLGTRGAVDSEPTLQSAATLVPEATSAQGPAQAQVRQPIMTTDMGMLGAGGPKPPKAKKKDRKDDDKDENRNSLEPATQQTTAPVIGSREGTAAENRETTPVQRHDGLLPPVIGARPGAIGVTGRAAGVPGGGKPTPPPPQVPRRTFTGNVSGVRAVARQYPAEGRIFRGGTTDGGGGQERPAPGYTRQPKAVHGDTDNPNRAVVRNSRAFGAEAAPPPVEPQPFEPTAESSRPSSEREWQTSRPVVAPVIRSRPHVEPEEVEHEPGPFLTHYNLGRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q929</accession>
    <name>D3Q929_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016209.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0927"/>
    <dbReference type="EnsemblBacteria" id="ADD40638">
        <property type="protein sequence ID" value="ADD40638"/>
        <property type="gene ID" value="Snas_0927"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0927"/>
    <dbReference type="HOGENOM" id="CLU_1353937_0_0_11"/>
    <dbReference type="OMA" id="MDSHTLA"/>
    <dbReference type="OrthoDB" id="1877572at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="202" mass="22350" checksum="7F0314C1472EF00B" modified="2010-04-20" version="1">MTNPYASGDEQWTVPDGLHQPEQEETFPQSMATPHAASTSQYLVYEHWGVFKGDWRGFPVLCFNVSVSDRISGPIPSMDSHTLAVELPVVCPLLSISPATALRPVRRLFGFGGTRFGHDGFDRRFQVDTSDKEFARRVLGPATTSWLLEHPVAAANPFRFEGVLLLMSNSGIMGPPEIVAPKLQFLCELYTRVPPGCWTADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q945</accession>
    <name>D3Q945_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cystathionine beta-synthase</fullName>
            <ecNumber evidence="4">4.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Beta-thionase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Serine sulfhydrase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Snas_0943</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-homocysteine + L-serine = H2O + L,L-cystathionine</text>
            <dbReference type="Rhea" id="RHEA:10112"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="4.2.1.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 1/2.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.22" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016225.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ADD40654">
        <property type="protein sequence ID" value="ADD40654"/>
        <property type="gene ID" value="Snas_0943"/>
    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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        <property type="term" value="F:cystathionine beta-synthase activity"/>
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    </dbReference>
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        <property type="term" value="P:cysteine biosynthetic process via cystathionine"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="CBS_dom"/>
    </dbReference>
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        <property type="entry name" value="CBS_dom_sf"/>
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        <property type="entry name" value="Cysta_beta_synth"/>
    </dbReference>
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        <property type="entry name" value="P-phosphate_BS"/>
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        <property type="entry name" value="PLP-dep"/>
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        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
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    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01137">
        <property type="entry name" value="cysta_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 11" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="334"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD40654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="454" mass="48540" checksum="B1709EB30FBEA0A2" modified="2010-04-20" version="1">MRYVNSVVDLIGNTPLVKLNAVTEGIEALVLAKVEYVNPGGSVKDRIATRMIEDAEKAGLLKPGGTIVEPTSGNTGVGLAMVAQQKGYKCVFVCPDKVSEDKRNVLKAYGARVEVCPTAVAPEDPRSYYNVSDRLVEEIPGAWKPDQYSNPANPRSHYETTGPELWEQTEGRLTHFVAGIGTGGTISGIGRYLKEQGPVKIVGADPEGSVYSGGTGRPYLVEGVGEDFWPDNYDRQVCDEIVEVSDAASFEMTRRLAREEGLLVGGSCGMAVEAALDVARRANPDDIIVVLLPDGGRGYLSKIFNDDWLTEYGFLSAGTSETTVADVLAGKGADIPEFVHVHPTDTVRDAIAILREYGVSQMPVLKAEPPVVTGEIAGAVAERDLLDALFTGTAHLHDPVERHLSAGLPLIGGGEPVEHAVNLLAKHDAATVLVDGKPRGIVTRQDLLTYIQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q947</accession>
    <name>D3Q947_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Multi antimicrobial extrusion protein MatE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0945</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0945"/>
    <dbReference type="EnsemblBacteria" id="ADD40656">
        <property type="protein sequence ID" value="ADD40656"/>
        <property type="gene ID" value="Snas_0945"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0945"/>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022017_4_0_11"/>
    <dbReference type="OMA" id="GLMPQFI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029303">
        <property type="entry name" value="Polysacc_synt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14667">
        <property type="entry name" value="Polysacc_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_C" evidence="7">
        <location>
            <begin position="353"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="495" mass="51858" checksum="13FFB3E73157BA24" modified="2010-04-20" version="1">MAQVAEAAPPRLRQPSTVLRATARGGLVNLAGAAVAGLSGLVITWLVAAGLGPRVAGQFFTATTAFLLALAIARLGTPTGLVYWFARLRQEGRHGELRSMLTAALVPVCALSLVFAVAGLVFAESFASAGILRVLAVFLPAAVLMEALLAASRGFGGMRESVLIDKLGRSGTQVVLLAAIVLGWQTGVFTVTVAWALPFLPAALLSAHVVRLRLRRDPPDPDSPSWTQQLRPFWTYTAPRALAGVAQLGLQRLDILLVATLLGFAQAAVYTVATRFVTVGQLISGAIGTAVQPRLATSMSGRDYATASTLYRTTTSWIVLACWPVYLLVALAAPWYLRVFGPEYVTGEAIAVVWVLAAGMLLATACGVVDSVLVMAGRTGWQLYNVAAAFAVNIVVDLLLIPRIGILGAAIGWTAGIAVNNLMPLLQLARVYRLHPIGRATLKAMALSGLCCGLIPGVAALAGEAALAVAIGGCAVIYPLSAWRARKTLFTTTDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9K3</accession>
    <name>D3Q9K3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_3014</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018256.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3014"/>
    <dbReference type="EnsemblBacteria" id="ADD42685">
        <property type="protein sequence ID" value="ADD42685"/>
        <property type="gene ID" value="Snas_3014"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3014"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_2_11"/>
    <dbReference type="OMA" id="WRAAWMG"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="10"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="127"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="256"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="406" mass="44035" checksum="DC5B7B7CF1972808" modified="2010-04-20" version="1">MTDGFSLELSEEQQTLRDWAHGFAADVVRPAASEWDEREETPWPIIGEAAKIGLYGFEALAQFWADPTGLSLPIVSEELFWGDAGIGLSIFGTSLAAAGIYSAGTPEQLAEWVPQCFGDADDVKLGAFCSSEPEAGSDVSAMRTRARYDEATDEWILSGQKAWATNGGIAHVHVVTASVDPELGSRGQAAFVVPPGTPGLSSPTKIKKLGLRASHTADVFLDDVRVPGRCLLGGKEKLDERLARARQPETRTKGQAAMRTFELTRPSVAAQAVGVARAAYEYALDYAKERVQFGRPIIDNQAVSFALADMRTEIDCARLLVWRAAWMGRNDKPFEAGEGSMSKLKAGEVAIKVTEKAVQLLGGAGFSRDHPVERMYRDAKIYTIFEGTSEIQRLVIARAISGRPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9P9</accession>
    <name>D3Q9P9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="5 6">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadE</name>
        <name evidence="11" type="ordered locus">Snas_4955</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>ATP + deamido-NAD(+) + H2O + L-glutamine = AMP + diphosphate + H(+) + L-glutamate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="5 6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020166.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4955"/>
    <dbReference type="EnsemblBacteria" id="ADD44595">
        <property type="protein sequence ID" value="ADD44595"/>
        <property type="gene ID" value="Snas_4955"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4955"/>
    <dbReference type="eggNOG" id="COG0171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022313_2_0_11"/>
    <dbReference type="OMA" id="VLMPSPY"/>
    <dbReference type="OrthoDB" id="1152435at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000257">
        <property type="term" value="F:nitrilase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000132">
        <property type="entry name" value="Nitrilase/CN_hydratase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00920">
        <property type="entry name" value="NITRIL_CHT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="10">
        <location>
            <begin position="4"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="557"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="565"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for glutaminase activity" evidence="5">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="active site" description="For glutaminase activity" evidence="5">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutaminase activity" evidence="5">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="330"/>
            <end position="337"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="552"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD44595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="586" mass="62996" checksum="1F64D286DC93ADA0" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA03</accession>
    <name>D3QA03_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hydrolase, TatD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1005"/>
    <dbReference type="EnsemblBacteria" id="ADD40715">
        <property type="protein sequence ID" value="ADD40715"/>
        <property type="gene ID" value="Snas_1005"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1005"/>
    <dbReference type="eggNOG" id="COG0084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031506_4_3_11"/>
    <dbReference type="OMA" id="PNEAPRI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004536">
        <property type="term" value="F:deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015991">
        <property type="entry name" value="Hydrolase_TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00010">
        <property type="entry name" value="TIGR00010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="272" mass="29425" checksum="B541C8BB4C33498A" modified="2010-04-20" version="1">MAVPDNHTHLDIVVGERAPEVGPGDAAVIAELDAASAVGIDRVVQVGIDVATSRWAVGLAELDSRVLAAVALHPNDAPRQGDLEGALGEIEALVKHPRVAALGETGMDFFRTGDEGRAAQEASFRAHIGMAKAHGKALMIHDREAHEDVLRVLDEEGAPETVVMHCFSGDAEHARECARRGYYMSFAGNVTFKNAPKLREAALACPRELMLVETDAPFMTPMPFRGRWNGPYLVPVTVRFLAELVGEDLERFCTDVSANTERVYGSWSVEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA33</accession>
    <name>D3QA33_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016316.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1035"/>
    <dbReference type="EnsemblBacteria" id="ADD40745">
        <property type="protein sequence ID" value="ADD40745"/>
        <property type="gene ID" value="Snas_1035"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1035"/>
    <dbReference type="eggNOG" id="COG1174">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_7_1_11"/>
    <dbReference type="OMA" id="DPLNWTN"/>
    <dbReference type="OrthoDB" id="1531811at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="27"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="236" mass="24120" checksum="32D503E71CC9F9A5" modified="2010-04-20" version="1">MNIFSEALTWLNDPLNWTNPDGVFALLGQHLALSGAALLLALVVAWPLGVWLGATGRGGTITVVVSNVTRAVPTMALLSLLPLTALGFGPQSVVPALALFGVPPLLATAYTGMREVDPDARDAAHGMGFSRSGMLFKVELPLAVPQLASGFRTAAVQIVATTTLAALFNGGGLGEIISRGFGLGLAKGGGEILAGGILVAGLALIVEGVLAVGEKYVTPIALRDLSRTKARVSMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA48</accession>
    <name>D3QA48_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-galactosidase</fullName>
            <ecNumber evidence="6">3.2.1.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1050</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016331.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1050"/>
    <dbReference type="CAZy" id="GH35">
        <property type="family name" value="Glycoside Hydrolase Family 35"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40760">
        <property type="protein sequence ID" value="ADD40760"/>
        <property type="gene ID" value="Snas_1050"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1050"/>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007853_7_2_11"/>
    <dbReference type="OMA" id="RAHPDTW"/>
    <dbReference type="OrthoDB" id="831762at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026283">
        <property type="entry name" value="B-gal_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="PTHR23421"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006336">
        <property type="entry name" value="B-gal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_35" evidence="5">
        <location>
            <begin position="12"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006336-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="580" mass="64031" checksum="966535CECA0E06DB" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA72</accession>
    <name>D3QA72_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016355.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1074"/>
    <dbReference type="EnsemblBacteria" id="ADD40784">
        <property type="protein sequence ID" value="ADD40784"/>
        <property type="gene ID" value="Snas_1074"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1074"/>
    <dbReference type="eggNOG" id="ENOG5033QBX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1077346_0_0_11"/>
    <dbReference type="OMA" id="ANCENMK"/>
    <dbReference type="OrthoDB" id="1677343at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048359" evidence="1">
        <location>
            <begin position="27"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="251" mass="28426" checksum="67305026AC022111" modified="2010-04-20" version="1">MKRGHTLLTIAVATAVVAAVPVYALAEDADPKPKPEAEAAETYADYSLMNQKHAGSVVGVDTGDVVTQWAWKPLADGSEIQWGDPKDGWPPKGGEHFEKDGDWVHMTGYYDHENDGFNKQEVTEESIGDANCENMKPLETDGRQRYAKWEIPSEGYCLRAKGTITVEANGAVVNFEHEQRWSPPRPCENRHLGQQTCIVQHETWWDDNQHDFEKVLERDQFIARGLGMAFRIDATFPKDWHAEMKDHRAYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAK2</accession>
    <name>D3QAK2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD-40 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3114</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018356.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3114"/>
    <dbReference type="EnsemblBacteria" id="ADD42785">
        <property type="protein sequence ID" value="ADD42785"/>
        <property type="gene ID" value="Snas_3114"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3114"/>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016652_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="560"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="695"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="730"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="772"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="424"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="474"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="506"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="816" mass="84691" checksum="7FE4D1BFC3583B89" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB13</accession>
    <name>D3QB13_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epoxide hydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1120</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016401.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1120"/>
    <dbReference type="EnsemblBacteria" id="ADD40830">
        <property type="protein sequence ID" value="ADD40830"/>
        <property type="gene ID" value="Snas_1120"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1120"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_1_11"/>
    <dbReference type="OMA" id="RTIAHVY"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033961">
        <property type="term" value="F:cis-stilbene-oxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EHN" evidence="4">
        <location>
            <begin position="4"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="374" mass="41783" checksum="27185A627B0E9C30" modified="2010-04-20" version="1">MTQIEPFTIDIAQSELDELTARLEHTRWPDELPGVGWSYGTALGYVRDLAGHWRDGFDWRAQEARLNELPQFTTRIDGQTIHFVHVRSPEPDALPLILTHGWPSTFADFAAMVGPLTNPRAHGGDPADAFDVVIPSVPGFAFSGPTTETGWDCQRVAAAWAELMRRLGYDRYGVQGSDFGALVTPRLARSQPDRVVGMHLNAVPTMPQVDPSEMDDLSAEEREYFAGMDQWEEVSGYAVVQSTRPQTLAYALSDSPVGQLAWYGDWYAAHGTKVGDLSPDRILTNVSLFWFTRTGGSAIRLYKESAAAWAEQPERSEVPTGLTFFKGENGVRRFAEREYRVTHWTHHDAGGHFAALEVPELLAGDIRTFFREVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB38</accession>
    <name>D3QB38_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-binding region ATPase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1145"/>
    <dbReference type="EnsemblBacteria" id="ADD40855">
        <property type="protein sequence ID" value="ADD40855"/>
        <property type="gene ID" value="Snas_1145"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1145"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017312_0_0_11"/>
    <dbReference type="OMA" id="HAGHEQK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="3">
        <location>
            <begin position="285"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="651"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="670" mass="71255" checksum="A4B6F6E5CFF7BE66" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB70</accession>
    <name>D3QB70_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit beta'</fullName>
            <shortName evidence="7">RNAP subunit beta'</shortName>
            <ecNumber evidence="7">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">RNA polymerase subunit beta'</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Transcriptase subunit beta'</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpoC</name>
        <name evidence="11" type="ordered locus">Snas_1177</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016458.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1177"/>
    <dbReference type="EnsemblBacteria" id="ADD40887">
        <property type="protein sequence ID" value="ADD40887"/>
        <property type="gene ID" value="Snas_1177"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1177"/>
    <dbReference type="eggNOG" id="COG0086">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000524_3_1_11"/>
    <dbReference type="OMA" id="YRNIRVE"/>
    <dbReference type="OrthoDB" id="4421at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01322">
        <property type="entry name" value="RNApol_bact_RpoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012754">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02386">
        <property type="entry name" value="rpoC_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 7 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RPOLA_N" evidence="10">
        <location>
            <begin position="310"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="148"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="535"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="537"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="539"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="880"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="956"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="963"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="966"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD40887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1293" mass="143496" checksum="1AC1E4BB0C2A1B3F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBA7</accession>
    <name>D3QBA7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsM</name>
        <name evidence="8" type="ordered locus">Snas_1214</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016495.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1214"/>
    <dbReference type="EnsemblBacteria" id="ADD40924">
        <property type="protein sequence ID" value="ADD40924"/>
        <property type="gene ID" value="Snas_1214"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1214"/>
    <dbReference type="eggNOG" id="COG0099">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103849_1_2_11"/>
    <dbReference type="OMA" id="YRGLRHK"/>
    <dbReference type="OrthoDB" id="1772647at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_S13_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="30s_Rbsml_prot_S13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019980">
        <property type="entry name" value="Ribosomal_S13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_S13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="PTHR10871:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03631">
        <property type="entry name" value="uS13_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="95"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="126" mass="14235" checksum="85EDA5F6963F52E7" modified="2010-04-20" version="1">MARLVGVDLPREKRLEIALTYIFGVGRTRSVETCAATGIDPSKRVHELTDAELVQLRDHIEGNYQVEGDLRREVAADIRRKVEIGCYQGIRHRRGLPVHGQRTRTNARTRKGPKRTVAGKKKPGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBC4</accession>
    <name>D3QBC4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016512.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1231"/>
    <dbReference type="EnsemblBacteria" id="ADD40941">
        <property type="protein sequence ID" value="ADD40941"/>
        <property type="gene ID" value="Snas_1231"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1231"/>
    <dbReference type="eggNOG" id="ENOG502ZX0U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1651129_0_0_11"/>
    <dbReference type="OrthoDB" id="2102208at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="160" mass="17159" checksum="0EB040E0F81E385A" modified="2010-04-20" version="1">MNGLSPVEQLSVTLTTVSSFQDTIRHADTKATILLTLQGSLAASIVANWNPHASPPVMICAAMFVCFATVSCVRFAVALRPRTDGLVVANRFGFVSVSAYPATCDGMDARRLQQDAWQLAVLLAEIAKIKHRHVLAGMPWLGASAIAALTVVSKWPDLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBK3</accession>
    <name>D3QBK3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018456.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3215"/>
    <dbReference type="EnsemblBacteria" id="ADD42885">
        <property type="protein sequence ID" value="ADD42885"/>
        <property type="gene ID" value="Snas_3215"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3215"/>
    <dbReference type="eggNOG" id="COG3324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141550_0_0_11"/>
    <dbReference type="OMA" id="GPVPYWH"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="117" mass="11944" checksum="2E9B5360754B70FF" modified="2010-04-20" version="1">MTTQGIKTVLHPVSDLARAKTVYTALLGVEPQTDGPYYVGFDVEGQHIGLVPGGGPANMTCPVAYWHVADIDASLAGLTAAGATVAEAVHDVGAGRRVATVTDTDTDGNVLGLLQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBX4</accession>
    <name>D3QBX4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Rieske (2Fe-2S) domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5229</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5229"/>
    <dbReference type="EnsemblBacteria" id="ADD44863">
        <property type="protein sequence ID" value="ADD44863"/>
        <property type="gene ID" value="Snas_5229"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5229"/>
    <dbReference type="eggNOG" id="COG4638">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026244_3_2_11"/>
    <dbReference type="OMA" id="TRAFTHD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015881">
        <property type="entry name" value="Ring-hydroxy_dOase_2Fe2S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015879">
        <property type="entry name" value="Ring_hydroxy_dOase_asu_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001663">
        <property type="entry name" value="Rng_hydr_dOase-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43756">
        <property type="entry name" value="PTHR43756"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00848">
        <property type="entry name" value="Ring_hydroxyl_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00090">
        <property type="entry name" value="RNGDIOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00570">
        <property type="entry name" value="RING_HYDROXYL_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="7">
        <location>
            <begin position="57"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="390" mass="44705" checksum="E51319DAF0D34C9E" modified="2010-04-20" version="1">MKHDEQVAIVKRLLALRESRRDQEMFDEVKTIPVSKYTDTALLDQELASAFTRYPLIASHTAALREPGSYVASDWDQFPYVVVRGEDGKVRGFYNQCRHRGARLLSERSGAIKNFICPFHGWVYGLNGELKGITRSQDFPCVDKSDYGLVELPVTESGGFVWISRTPDAISDIPAFMGRFHDDLESFEVANLVRYKKTKVVKNANWKLLIKTYLEGYHVPYLHRDTLATAFKRGQLAYDKDGPHIRMMAGRTNLTDITAKPEAEWRILDHVSIYYTLFPNTFFILHPDYVSVNTFWPQAPDRTIWTHEMLYRAEDFNGSSGQSALEKRFRFTNDTVFDQEDFAIAEEVQRNLLHGGSDHHVLGLSEGLLAMFQDNIDERLAIHAAQGTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTY0</accession>
    <name>D3PTY0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0015</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015309.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0015"/>
    <dbReference type="EnsemblBacteria" id="ADD39738">
        <property type="protein sequence ID" value="ADD39738"/>
        <property type="gene ID" value="Snas_0015"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0015"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_3_11"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="401"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="17"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD39738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="457" mass="46816" checksum="5E65681B142F6E4A" modified="2010-04-20" version="1">MTHTPETSTGEKTRWAPIVALAMAMVVITSDMTIAAVTLPSLGEDMDVGAAATAWVLLGYSLPMAAIAIPAGRWADRADLRAVFVLSMTGVAVASVAAALAPTFWVLVVARLLQGFTGALTMSVYMPIVAAAVKTEQRGRAIGYIITIMTLGGLIGAPLGGLVAGGLGWRAVFLLKLPIVAVAIVLALKSVPSNGKRLPLPDAALWRDTLVVGGAVGSLLLAFDRIERQPLAATGLIALAVVLAVLWLRFRSSRPMVAVLGRRVLGLPMLGLFLMSFMIGLISFLLPYYFTDELNTGPEAMGVAMLFFSGAMAPISPLAGGLADRFGALRIASAGAVVSILGLGSMLTLGPDSSMVDVIWRLVLLGVGAALFNGPINAALMAATPADMLGTAGGMFATTRTLASTIGPAVTAFVWSTAGGGMPGFTTATAVLTALSVLGLGFVLAGRSRQPALATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU30</accession>
    <name>D3PU30_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1267</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016547.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1267"/>
    <dbReference type="EnsemblBacteria" id="ADD40976">
        <property type="protein sequence ID" value="ADD40976"/>
        <property type="gene ID" value="Snas_1267"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1267"/>
    <dbReference type="eggNOG" id="ENOG502Z7QC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062259_0_0_11"/>
    <dbReference type="OMA" id="VTLNFHP"/>
    <dbReference type="OrthoDB" id="636716at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022074">
        <property type="entry name" value="DUF3626"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12294">
        <property type="entry name" value="DUF3626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="282" mass="30946" checksum="87FCC8A34107B8C3" modified="2010-04-20" version="1">MSAEGSPSARQRALDHVAALASGPAIDPALRVSLNFHPDRMLRDKPILDVLADDGVYCSQFVTGTSNGGLTAFPGGDRWRWESRIFDRAYDEAPADERPVYGALNFRGKPVGAAPRFGSAHFRLTADTLARTTFCYPDSVFEPSDFGVADRMGLIAIALADRQDDLDDYVEAQVHGPVLLRSHVEALVLDPCYRGTEVEASATRLGCAVEWHSGFRLTVAELRRYPEYRGPQFVELGERIAIDGVLDPGIIGDAARSGRFDPQAVKRVWHYLARFGNRPNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU68</accession>
    <name>D3PU68_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016585.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1305"/>
    <dbReference type="EnsemblBacteria" id="ADD41014">
        <property type="protein sequence ID" value="ADD41014"/>
        <property type="gene ID" value="Snas_1305"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1305"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_540671_0_0_11"/>
    <dbReference type="OMA" id="YLSFHGY"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="377"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="509" mass="55820" checksum="3AC23308C37BD041" modified="2010-04-20" version="1">MSTDATTERLRRARQLMVDGDPAKAIDAADEIIADTSDAEERVWALLLRLTAVVALERTTEYTSTVDRAYAAVRRHGDTVASGFFHALAAYTSHADGSIERCVTHLVRSTRALSSVDIASRSTAVAWHNLAVVYSYIGFHEHAAQAAARARELAAEAELNWQLPTLEVPVRQGLSLDHRGDTDGCVRVLRTLLTNATYIPQGPDGLPGIAPMDLPWLGFAAARLNALGHETPIEARRCLAAGYNDAWSADLRHYGRVCLNIAAGETDKARQRLTRATSTAAVLGAAEAARLKALSYVNDGDYQAAWRADREAFAIHARIDDQLRRLFVDGVATRLDHEDLRRTVASYGDRALTDPLTGLPNRRHLQEYVDDQNASGQAGVLGVLDLDGFRQVNTTHGRLSGDTILQRTAGALMRVMRRGDFVARYGADEFALVLQGTPIDQTGDISRRITNALDDEDWESLVPGYQPRVNIGWTTLDIQRNPERDPQNLSIADVAVTKAKRARQSSQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUB7</accession>
    <name>D3PUB7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1355</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016634.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1355"/>
    <dbReference type="EnsemblBacteria" id="ADD41063">
        <property type="protein sequence ID" value="ADD41063"/>
        <property type="gene ID" value="Snas_1355"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1355"/>
    <dbReference type="eggNOG" id="COG1079">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040769_1_0_11"/>
    <dbReference type="OMA" id="MIFGNWM"/>
    <dbReference type="OrthoDB" id="1215743at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="430" mass="44813" checksum="81530D2844157A9F" modified="2010-04-20" version="1">MTTVSVAETAESRELHGFWTRSRKVGVVLIVLGLATVLGAFATVGSGTTAEMMLDKTADTFGWDATWAVPARLAIVLLAVVATGAGIFLATGAPRYFTTATVIGFAAFVLALLVWAVSSAKGDDPLKIEFVLAGALFAALPLIFGALAGVLCERSGVINVGIEGQLLAGAFCGALFATMTGNVWVGLVTAAVAGSLVTTLLGALAVRFQVDQVVLGVILNLLVLGVTGYLFDQVMKEDASTFNDPPDAPEWAVPLLSKIPVIGPMLFDQSIFGYVAIILVFAIWFLLFMTPWGLRTRAVGEHPQAADTLGVKVNLLRFRNVAMAGLVAGFGGAVFTIGDGLGFAKNMTVGKGFIALAVLIVGRWHPLGALLGALLFGFADQIGQFLRVIGSPVPSSFLSMLPYLVTIVAVAGLIGKVRAPAADGKPYIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUP9</accession>
    <name>D3PUP9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Formamidopyrimidine-DNA glycosylase</fullName>
            <shortName evidence="15">Fapy-DNA glycosylase</shortName>
            <ecNumber evidence="15">3.2.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">DNA-(apurinic or apyrimidinic site) lyase MutM</fullName>
            <shortName evidence="15">AP lyase MutM</shortName>
            <ecNumber evidence="15">4.2.99.18</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">mutM</name>
        <name evidence="15" type="synonym">fpg</name>
        <name evidence="19" type="ordered locus">Snas_5289</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.</text>
            <dbReference type="EC" id="3.2.2.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 15">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the FPG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.23" evidence="15"/>
    <dbReference type="EC" id="4.2.99.18" evidence="15"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020494.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5289"/>
    <dbReference type="EnsemblBacteria" id="ADD44923">
        <property type="protein sequence ID" value="ADD44923"/>
        <property type="gene ID" value="Snas_5289"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5289"/>
    <dbReference type="eggNOG" id="COG0266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038423_1_2_11"/>
    <dbReference type="OMA" id="GVHLRMT"/>
    <dbReference type="OrthoDB" id="1162346at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00103">
        <property type="entry name" value="Fapy_DNA_glycosyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020629">
        <property type="entry name" value="Formamido-pyr_DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000214">
        <property type="entry name" value="Znf_DNA_glyclase/AP_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00577">
        <property type="entry name" value="fpg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51066">
        <property type="entry name" value="ZF_FPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9 15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13 15 19" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 15 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 15 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FPG_CAT" evidence="18">
        <location>
            <begin position="2"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="FPG-type" evidence="17">
        <location>
            <begin position="243"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DNA" evidence="15">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="3"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for beta-elimination activity" evidence="15">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for delta-elimination activity" evidence="15">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ADD44923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="280" mass="31357" checksum="E5B9AE0235CF6D65" modified="2010-04-20" version="1">MPELPEVETIRRGLDGWVIGRRITDVEVRHPRAVRRHHAGPADFRARLLGTTITGTRRRGKFLWLPLDSGDALLCHLGMSGQLLIEPPDKPDGPHLRIRLVFDQAEHQLRFVDQRTFGEMLVSPDGAELPGEIAHIAPDIYDPAFDLAEFSRRLRARRGEVKRALLDQSLISGVGNIYADEALWRARLHGNHPSQELSDAVARELVEHIREVFDAALNAGGTSFDALYVNTNGESGYFDRSLAVYGRAEEPCRRCGTPVERIKFTNRSSFHCPSCQIVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUV8</accession>
    <name>D3PUV8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Uncharacterized N-acetyltransferase Snas_5348</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5348</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Homohexamer; trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the acetyltransferase Eis family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020553.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5348"/>
    <dbReference type="EnsemblBacteria" id="ADD44982">
        <property type="protein sequence ID" value="ADD44982"/>
        <property type="gene ID" value="Snas_5348"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5348"/>
    <dbReference type="eggNOG" id="COG4552">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050659_0_0_11"/>
    <dbReference type="OMA" id="DWLWVRL"/>
    <dbReference type="OrthoDB" id="1497065at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01812">
        <property type="entry name" value="Eis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041380">
        <property type="entry name" value="Acetyltransf_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025559">
        <property type="entry name" value="Eis_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022902">
        <property type="entry name" value="NAcTrfase_Eis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17668">
        <property type="entry name" value="Acetyltransf_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13530">
        <property type="entry name" value="SCP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="5">
        <location>
            <begin position="6"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="4">
        <location>
            <begin position="83"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="4">
        <location>
            <begin position="91"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; via carboxylate" evidence="4">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="412" mass="44894" checksum="BC29A0E8B848F3D8" modified="2010-04-20" version="1">MTTDPYSLRPVTDTEFAPWCRMIADTYGQDLTDADLAIKRAATDLDRTIGAFDGPTPVGGVSIYPRELTVPGAEISTAGIAFVAVAPTHRRRGILTAMMRRQLAELHEHGESVAALRPAEAGIYGRYGYGPASRGVMLRLDKRAMAFRADVDFGGGAIALADPVEARSTLTKLYDRRRHSTVGWSDRDEAAWDLRLFDPPERRGDATALRVAVHTEPGGEVTGYALYRRVGNPDGSRAVRLQELVAFSLPAYASLWRFFAGFDLTDWIEYEAAVDEPLPHLLVDPRPARADTMDRLWVRLVDVDKALASRRYSAPLETVLEVEDAVCPWNTGRFRLLADGDDVSCEPTAAPAELRLSAAELGAAYLGGTSLTSLAAAGLVEELSPGALGRADAAFRGHREPFYPGGWAFPLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV21</accession>
    <name>D3PV21_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MDMPI_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016645.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41074">
        <property type="protein sequence ID" value="ADD41074"/>
        <property type="gene ID" value="Snas_1367"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1367"/>
    <dbReference type="eggNOG" id="ENOG50314EV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094601_0_0_11"/>
    <dbReference type="OMA" id="DIDWTHG"/>
    <dbReference type="OrthoDB" id="2054078at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="1">
        <location>
            <begin position="18"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="224" mass="24268" checksum="10CE2EE74833DC94" modified="2010-04-20" version="1">MSPEPTDAATASRMELARRERTELAGFLAELSDEQWQAPSLCEGWRVRDVVAHVISYDELSRWATARRLLRAGFSLKRGNTIGLAHYESHTPRQLLDALNAHLTPRGLTTAFGGMVALVDGTIHHQDIRRPLGMPRRIPPERLAVVLRLALGAPPIKARQRAKGLRLVATDCDFVTGTGPEVRGPGEALLMTLAGRPGVASELAGDGQPILAGRVSERAIPDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV37</accession>
    <name>D3PV37_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1383"/>
    <dbReference type="EnsemblBacteria" id="ADD41090">
        <property type="protein sequence ID" value="ADD41090"/>
        <property type="gene ID" value="Snas_1383"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1383"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_294889_0_0_11"/>
    <dbReference type="OMA" id="MVTGRCL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048392" evidence="2">
        <location>
            <begin position="45"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="509"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="889"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="944"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1009"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1026" mass="109266" checksum="08F21F45E8A3DC18" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVA9</accession>
    <name>D3PVA9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase S58 DmpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S58 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016733.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1456"/>
    <dbReference type="MEROPS" id="P01.101"/>
    <dbReference type="EnsemblBacteria" id="ADD41162">
        <property type="protein sequence ID" value="ADD41162"/>
        <property type="gene ID" value="Snas_1456"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1456"/>
    <dbReference type="eggNOG" id="COG3191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044458_1_0_11"/>
    <dbReference type="OMA" id="HTRFDGD"/>
    <dbReference type="OrthoDB" id="2000083at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005321">
        <property type="entry name" value="Peptidase_S58_DmpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36512">
        <property type="entry name" value="PTHR36512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03576">
        <property type="entry name" value="Peptidase_S58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="SSF56266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="300" mass="29694" checksum="2DC0D0A0372B3678" modified="2010-04-20" version="1">MLAELGVRMGHWTDGAARTGCTVLLLPEGATGSAEVRGGAPASRELELLAPERTVAQVDAIVLTGGSAFGLASADGVMRYCEESGRGVATPAGRVPIVPALGLFDLAVGDASVRPGAAEGYAACVAAAEATAGSGDGGVDVIGAVGAGAGATVGKINGPNGMRPGGLVANARRAGELLVACVVAVNAFGEIDVDGSAALRLARRHGEPRPGPLFDESEGGAGLGNTTIGAVVTNARLDKVGCLLVCQGAHDGLSRAIVPPHTRFDGDAFIAAATGMVEADVDTVRLLALTVVDEAIRSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVR9</accession>
    <name>D3PVR9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3520"/>
    <dbReference type="EnsemblBacteria" id="ADD43183">
        <property type="protein sequence ID" value="ADD43183"/>
        <property type="gene ID" value="Snas_3520"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3520"/>
    <dbReference type="HOGENOM" id="CLU_2977084_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049282" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="58" mass="5965" checksum="6CE7ED40B0231742" modified="2010-04-20" version="1">MPPPPISRRGVLGLSAAAVVAATTTAITVHSASADNAKETKDVHPMVIECLADLNARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW08</accession>
    <name>D3PW08_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S1 and S6 chymotrypsin/Hap</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5498</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020700.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5498"/>
    <dbReference type="MEROPS" id="S01.101"/>
    <dbReference type="EnsemblBacteria" id="ADD45129">
        <property type="protein sequence ID" value="ADD45129"/>
        <property type="gene ID" value="Snas_5498"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5498"/>
    <dbReference type="eggNOG" id="COG5640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006842_7_0_11"/>
    <dbReference type="OMA" id="LGCAHAN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048026" evidence="2">
        <location>
            <begin position="31"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="3">
        <location>
            <begin position="43"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="275" mass="28262" checksum="F8625EFA532329D5" modified="2010-04-20" version="1">MQKKTKRLAAVGAALAAGALAVGVSLPALAADTDKSNGPEEKVVGGEPAEEGEFPFMMRLTIGGQDACGASLIRPDVALTAAHCTDGSEGFTVKYGTNKLDDPEIKEIKVTEVTQNPDFGKPIEMAGDWSVLKLEAPAEGVEPVKLAEDDSVDLEEQTIMGWGATSEGGEQSNELLKAKVPGVDDEKCKEAYGESLDPDSMLCAGLDEGGIDTCQGDSGGPMGVVAEDGTFTQTGIVSWGEGCAQPKKFGVYAQVSTLAADINAAADAFGGGEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW45</accession>
    <name>D3PW45_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tryptophan synthase, beta chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016773.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1498"/>
    <dbReference type="EnsemblBacteria" id="ADD41202">
        <property type="protein sequence ID" value="ADD41202"/>
        <property type="gene ID" value="Snas_1498"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1498"/>
    <dbReference type="HOGENOM" id="CLU_2439328_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="SSF103647"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="90" mass="9635" checksum="C1B1F524A26AA15B" modified="2010-04-20" version="1">MTEPDIATGDFDGDGVEDDTAYGYDDNNDGVYDQVDVDLNTDGGNDVSGFDQNDDGVYDHVQYDSDGDGEQDSAMSDTNYDGTIDEQGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWM1</accession>
    <name>D3PWM1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CRISPR-associated helicase Cas3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3582</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3582"/>
    <dbReference type="EnsemblBacteria" id="ADD43243">
        <property type="protein sequence ID" value="ADD43243"/>
        <property type="gene ID" value="Snas_3582"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3582"/>
    <dbReference type="eggNOG" id="COG1203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010123_0_0_11"/>
    <dbReference type="OMA" id="HLSTNMC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035011">
        <property type="entry name" value="Cas3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006483">
        <property type="entry name" value="CRISPR-assoc_Cas3_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF5">
        <property type="entry name" value="PTHR47959:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01596">
        <property type="entry name" value="cas3_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51643">
        <property type="entry name" value="HD_CAS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD Cas3-type" evidence="6">
        <location>
            <begin position="10"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="759" mass="82695" checksum="E1507542F3F65EE6" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWX0</accession>
    <name>D3PWX0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45194">
        <property type="protein sequence ID" value="ADD45194"/>
        <property type="gene ID" value="Snas_5563"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5563"/>
    <dbReference type="HOGENOM" id="CLU_1703169_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="154" mass="16403" checksum="36EFC0CEDE832DCB" modified="2010-04-20" version="1">MSSVNLRSVSGGPRRTIVVIGWLIAAISVFHLVMLTFFGARVIPGWVDGALRGAEAEDFASMTVSEGYFWSSLGGFAFPLFALGLLIVWLARAGVAPPVFVYLVLLAWSVPGTLVFFPGGYLALIPMTVILLVADAKSRKLTTAQVSARTAASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX81</accession>
    <name>D3PX81_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016915.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1641"/>
    <dbReference type="EnsemblBacteria" id="ADD41344">
        <property type="protein sequence ID" value="ADD41344"/>
        <property type="gene ID" value="Snas_1641"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1641"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="ITHRFRV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="276" mass="30089" checksum="5C08162F3EA38534" modified="2010-04-20" version="1">MAVDDGHVDGVGTVVGDVLDGYTITHRFRVRGCTAVYQAARGDRTVALKTLCRGAIARAQLRMDNEIASLRVLGESAPAPRLLRLGIAGPQRYFAMSWQPGGSLRRQTEARDLDGFAEIAVPVCEAYAALHRAGVAHGDVSRHNILIDGHDVGLVDFESSARTSEADDDGLRRRFTWAYAAPEFADRQQPSPASDQYAVAAVLYRQLTGRYPRRQIDGVKPDSRRALTARARLLTGAPHRRWPGLRDVFTTALSREPADRFGDMGELARALAAAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX90</accession>
    <name>D3PX90_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FMN dependent NADH:quinone oxidoreductase</fullName>
            <ecNumber evidence="6">1.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Azo-dye reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">FMN-dependent NADH-azo compound oxidoreductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">FMN-dependent NADH-azoreductase</fullName>
            <ecNumber evidence="6">1.7.1.17</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">azoR</name>
        <name evidence="8" type="ordered locus">Snas_1651</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 a quinone + H(+) + NADH = 2 a 1,4-benzosemiquinone + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:65952"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="ChEBI" id="CHEBI:134225"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>anthranilate + N,N-dimethyl-1,4-phenylenediamine + 2 NAD(+) = 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 H(+) + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:55872"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15783"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:71579"/>
            <dbReference type="EC" id="1.7.1.17"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="5">
            <dbReference type="Rhea" id="RHEA:55874"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="6">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the azoreductase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.-" evidence="6"/>
    <dbReference type="EC" id="1.7.1.17" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016924.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41353">
        <property type="protein sequence ID" value="ADD41353"/>
        <property type="gene ID" value="Snas_1651"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1651"/>
    <dbReference type="eggNOG" id="COG1182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088964_0_0_11"/>
    <dbReference type="OMA" id="REGWDHS"/>
    <dbReference type="OrthoDB" id="1402654at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016652">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01216">
        <property type="entry name" value="Azoreductase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003680">
        <property type="entry name" value="Flavodoxin_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023048">
        <property type="entry name" value="NADH:quinone_OxRdtase_FMN_depd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02525">
        <property type="entry name" value="Flavodoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 6" id="KW-0288">FMN</keyword>
    <keyword evidence="4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_2" evidence="7">
        <location>
            <begin position="3"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="15"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="215" mass="23898" checksum="DF68832FEBADE1C2" modified="2010-04-20" version="1">MTTLLRVDSSPRDNSISRALGDAFERTWRAAHPDGRVLTRDLARVPVPFIDAAWTEICDHLLAHRITDLDRLSEAARTPDQKRAWAIVEPLLTELRAADVVLITTPMHNFSIPAVLKAWLDQVTFPRMSLAGKRFVVATARGGAYSPGAPKAKFDYQERYLRDFFAGHFAVDDARFVNAELANARVDPLLADHRTTHESSYADAIATAAELGGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXJ4</accession>
    <name>D3PXJ4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3666</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018895.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3666"/>
    <dbReference type="EnsemblBacteria" id="ADD43324">
        <property type="protein sequence ID" value="ADD43324"/>
        <property type="gene ID" value="Snas_3666"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3666"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="NDWVATY"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="241" mass="25607" checksum="BB93229B4F12C8F0" modified="2010-04-20" version="1">MTTVASVAKLGFAYPATPVLHDVDMTVHAGHIHALIGLNGAGKTTLMRAVLGMLTPDTGTATLFGQPAATAPALVWKRVGYLLGTESTYGELTGRENIYAAARLHGLDRHAARQATEAAITEFGIEAEAGKRAARLSMGNRQRVALAAAFAHRPDLLVLDEPTIALDPLAVVALRRSLRDATHRGAAILVSSHHLDEVARLADDITVIHRGRITATLDPGGTDLEKQFFDLVYAAELEDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXU2</accession>
    <name>D3PXU2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018993.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3765"/>
    <dbReference type="ESTHER" id="stanl-d3pxu2">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43422">
        <property type="protein sequence ID" value="ADD43422"/>
        <property type="gene ID" value="Snas_3765"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3765"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_13_3_11"/>
    <dbReference type="OMA" id="CEAFDNY"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="24"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="285" mass="30924" checksum="58F0D57AC6A0980A" modified="2010-04-20" version="1">MWKTKNIDLSAGTIDYLDTGGTKPVLVLVHGLLMDETLWTDVVAELAPEYRCVVPVLPLGAHRHAMSHGADLSLPGVARLLAEFVDRLGLTDVTLVGNDTGGAVVQLLMAEPAASVARAVLVSCEAFDNLPPGLTGRALVLTGKLPPRLFGLFMRQLRLKPMRRLPFVFGWLTRRGDAVTAGWVTPVIGDVAVARDATRTLRSIASNRKLLLDNATRLPGFDRPVLVVWAKNDRVMPPEHGERLAELLPDARLTVVDDTDALIPLDQPTALAGHIREFVAERAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXV5</accession>
    <name>D3PXV5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Radical SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_5654</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the radical SAM superfamily. NifB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5654"/>
    <dbReference type="EnsemblBacteria" id="ADD45284">
        <property type="protein sequence ID" value="ADD45284"/>
        <property type="gene ID" value="Snas_5654"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5654"/>
    <dbReference type="eggNOG" id="COG0641">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009273_3_1_11"/>
    <dbReference type="OrthoDB" id="1172757at2"/>
    <dbReference type="UniPathway" id="UPA00782"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023885">
        <property type="entry name" value="4Fe4S-binding_SPASM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005980">
        <property type="entry name" value="Nase_CF_NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43787:SF3">
        <property type="entry name" value="PTHR43787:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04085">
        <property type="entry name" value="rSAM_more_4Fe4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="9">
        <location>
            <begin position="88"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD45284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="449" mass="49782" checksum="111B7950DAE2E9E1" modified="2010-04-20" version="1">MTTVTYGPSKYVSFAFDNDGALIVQSTRTGAIGVVPSDKAEDARKALLPGSTVSNTSDGILKDLKDGGFLVPSTMDEDQLVHDRYIKRYQKNRLDLILMPTEQCNFRCVYCYESFIRGEMSPELVAGLHSFIAAEHRVNGLESLNVSWFGGEPLLAADLVLDTTRSLADYCRANGIASKFSATTNGYLLKPGYAEKVVQAGVRHFQITLDGTKHDHDKRRVDIDGAETFDVIMANLRHLKSTDLDFTIMLRHNFDPEGLRRLDDYIDMIQREFSDDPRYTTHFAAIGKWGGAKDDDLVVCEGRTGPQAIAHARGLAISAGFKVDLLENGLKPEGSICYAADPRSFVIGSDGTVYKCTVELDYHERNMVGKLHPDGTMDLDWRKLALWCETDGTDPGKKCNSCYFGGACHGAACPKEWMDEDDCHCPPSKQVIRETLPLVRRNFAAGVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ64</accession>
    <name>D3PZ64_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021064.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5864"/>
    <dbReference type="EnsemblBacteria" id="ADD45493">
        <property type="protein sequence ID" value="ADD45493"/>
        <property type="gene ID" value="Snas_5864"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5864"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140929_0_0_11"/>
    <dbReference type="OMA" id="PLGHHVT"/>
    <dbReference type="OrthoDB" id="1736098at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="133" mass="13923" checksum="728B9636E99DE222" modified="2010-04-20" version="1">MTITADDRAAISELLAMHGHLIDAGELDRLDEVLTPDAIYDVTDLGAAPLVGVAACREAALALGEGNPLGHHVTNIVITESTPGRVFARSKGIGVNTDGTTGTVTYEDTITRSPAGWRISHRKVIARRAPLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ70</accession>
    <name>D3PZ70_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type II secretion system protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5870</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021070.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5870"/>
    <dbReference type="EnsemblBacteria" id="ADD45499">
        <property type="protein sequence ID" value="ADD45499"/>
        <property type="gene ID" value="Snas_5870"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5870"/>
    <dbReference type="eggNOG" id="COG4962">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005379_8_0_11"/>
    <dbReference type="OMA" id="HDERVIT"/>
    <dbReference type="OrthoDB" id="473670at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022399">
        <property type="entry name" value="HlxAse/secretion_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03819">
        <property type="entry name" value="heli_sec_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048716" evidence="2">
        <location>
            <begin position="29"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="T2SP_E" evidence="3">
        <location>
            <begin position="58"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="387" mass="40373" checksum="D5047ACA4BE6C013" modified="2010-04-20" version="1">MTSRLVAAVRRSLSGSAAPITPATVAHAVRQTAPAPLAGPAVLAETVRVDAELTGAGPLQPLLDDPHVTDVLVNGPHQVWADRGHGLEPTPVHFADEATVRRLAVRLAAAGGRRLDDAHPYADVRLPDGTRLHAVLPPIAVNGPHLSLRTHRAKALTMDELTTAGTLTPTSAALLSALVAAKTAFIISGGTGSGKTTLLASLLGTVDPSERIVIVEDATELAPAHPHALSLQSRHTNIEGAGAVSLRHLVRQALRMRPDRIVVGECRGAEVIELLTALNTGHDGCAGTLHANTATDVPARLAALALPHGLPRAGLHALVAAALRVIVHMDRKAGRRIVGEIALLSHDEPNARLTVTPAWNHTHGDQPGIQALHQLLANPSAPTRSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZE4</accession>
    <name>D3PZE4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1922"/>
    <dbReference type="EnsemblBacteria" id="ADD41618">
        <property type="protein sequence ID" value="ADD41618"/>
        <property type="gene ID" value="Snas_1922"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1922"/>
    <dbReference type="eggNOG" id="ENOG50333N5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183045_1_1_11"/>
    <dbReference type="OMA" id="FPRFYWL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021741">
        <property type="entry name" value="DUF3311"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11755">
        <property type="entry name" value="DUF3311"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="75" mass="8707" checksum="9F86714918DC5AB2" modified="2010-04-20" version="1">MSTSPERTRKSDLSPWNWLLLLPIAVPLMPFLFNFDEPRLLGFPAFYWIQLAFIILGVTTTTFVYRITKAKGDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZP3</accession>
    <name>D3PZP3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase associated with various cellular activities AAA_3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3925"/>
    <dbReference type="KEGG" id="sna:Snas_3925"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034716_2_0_11"/>
    <dbReference type="OMA" id="NRFQMND"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0711">Selenium</keyword>
    <keyword evidence="3" id="KW-0712">Selenocysteine</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="46"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="240"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="non-standard amino acid" description="Selenocysteine" evidence="3">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="336" mass="36841" checksum="8E4F7AB162B2F675" modified="2010-04-20" version="1">MSTDVSMPLSEVTKRATEVLDAVNQVVVGKRESLELVLAGILAGGHVLFEDLPGLAKTLTARUFAQTLGLHFNRLQFTPDLLPADVTGSFLYNQKQADFQFRQGPIFTNLLLADEINRTPPKTQAALLEAMQERQVSVEGTTYRLPQPFFVLATANPIEQEGTYPLPEAQLDRFLLRVTFGYPDRGEEWEVLRRRLSRRREEAQLSPIVDAATVVAMQDALEDVAFDDSIGQYIVEIVAATREHPQLQVGASPRGSLALTLLSRAKAVLAGRDYVIPEDVKTVAPAALTHRVSLKPELWLQQVDPAAVIAEVCARVPAPATNLMPSYTAQQGAVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q117</accession>
    <name>D3Q117_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="2">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4116</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019338.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4116"/>
    <dbReference type="EnsemblBacteria" id="ADD43767">
        <property type="protein sequence ID" value="ADD43767"/>
        <property type="gene ID" value="Snas_4116"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4116"/>
    <dbReference type="eggNOG" id="COG1893">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031468_6_1_11"/>
    <dbReference type="OMA" id="WEKWVFL"/>
    <dbReference type="OrthoDB" id="427052at2"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApbA" evidence="3">
        <location>
            <begin position="4"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="ApbA_C" evidence="4">
        <location>
            <begin position="178"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="308" mass="32168" checksum="3604B0A0D78FA9D6" modified="2010-04-20" version="1">MRTLIVGAGAVGGYFGSRLVHSGQDVTFLVRPRRAELLRRRGLRVTGLGEDTVVEPRLVTAPELTGDYDAILLAVKATGFEQALADVAPAVGDDTAILPLLNGMAHLDRLNERFGPARVLGGVAKVMTTVDDEGDIVRLGPLEHILLGEQDGRPSSRVDDIHATLTKAGIPSDTSTAVLGAMWSKWVFISALGAVTTLLDGTVGEANSVPGGTAVAAAITREAAAIAERSGFGLSEAALTAVLSTTTDPDSPVTPSLYRDLTSGLPTEVEHLFGDLIARARDLGVDTPLLDAATARLRVHERRLAAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1B2</accession>
    <name>D3Q1B2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyruvate dehydrogenase (Acetyl-transferring) E1 component, alpha subunit</fullName>
            <ecNumber evidence="5">1.2.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6068</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021263.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6068"/>
    <dbReference type="EnsemblBacteria" id="ADD45692">
        <property type="protein sequence ID" value="ADD45692"/>
        <property type="gene ID" value="Snas_6068"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6068"/>
    <dbReference type="eggNOG" id="COG1071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029393_1_0_11"/>
    <dbReference type="OMA" id="GMFRGVN"/>
    <dbReference type="OrthoDB" id="1248201at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017596">
        <property type="entry name" value="PdhA/BkdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516:SF41">
        <property type="entry name" value="PTHR11516:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03181">
        <property type="entry name" value="PDH_E1_alph_x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E1_dh" evidence="4">
        <location>
            <begin position="59"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="385" mass="42452" checksum="55F3DD18529AF34E" modified="2010-04-20" version="1">MVNGDQTRSGPKAKSPARRKKTPVGDPDMVQLLTPDGKRVSHPDYAVDLTDEEYRGLYRDMVIVRRLDSEGTALQRQGQLGIWASLLGQEAAQIGSGRALAAQDMVFPTYREHGVLWTKGIDPIMPFGLFRGVDLGGWDSRKYKFQMYTIVIGAQTLHATGYAMGITMDGKVGTDDGEAVIAYFGDGASSQGDVNESLVFSSVYNSPIVFFCQNNQYAISEPVFRQAKAPLFKRADGFGFPGVRVDGNDVLATYAVTKTAMDNARSGNGPTFIEAFTYRMGAHTTTDDPTRYRDSVEVDQWKAKDPISRMRTFLEAEKLADADWLAGVDAEADEHALSLRERVISMPDPDPDSMFQHVFREGSPLVDSERAAFADYHASFEGSEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1G3</accession>
    <name>D3Q1G3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_6119</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021314.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6119"/>
    <dbReference type="EnsemblBacteria" id="ADD45743">
        <property type="protein sequence ID" value="ADD45743"/>
        <property type="gene ID" value="Snas_6119"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6119"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="22"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="106"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="174" mass="20200" checksum="714F5018B590C126" modified="2010-04-20" version="1">MYQRPPPNPRFDEFVRARSASLLRAAFLLTGGDQHQAEDLVQSALARTLRAWSRLEREDNAEAYTRKTMYHLQVGWWRRRARERRANKLLHPQEIVADGADDVLRRLALKSVLRRLTPKQRAVLVLRFYEDLSVAETADVLECSPGTVKSQTAKALTLLRDRAPQLRELRRAWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1U4</accession>
    <name>D3Q1U4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0223</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015513.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0223"/>
    <dbReference type="EnsemblBacteria" id="ADD39942">
        <property type="protein sequence ID" value="ADD39942"/>
        <property type="gene ID" value="Snas_0223"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0223"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_1_7_11"/>
    <dbReference type="OMA" id="ATSWSNY"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048557" evidence="6">
        <location>
            <begin position="34"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="7">
        <location>
            <begin position="535"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD39942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="596" mass="61203" checksum="48F3A2E3656D5C01" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q294</accession>
    <name>D3Q294_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cation diffusion facilitator family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4176</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019398.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43827">
        <property type="protein sequence ID" value="ADD43827"/>
        <property type="gene ID" value="Snas_4176"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4176"/>
    <dbReference type="eggNOG" id="COG0053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021126_0_0_11"/>
    <dbReference type="OMA" id="YLVIHMD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006829">
        <property type="term" value="P:zinc ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040177">
        <property type="entry name" value="SLC30A9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13414">
        <property type="entry name" value="PTHR13414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="318" mass="33795" checksum="29D8FEB49D04BD59" modified="2010-04-20" version="1">MTTGQTIPEAPESETLGTVIVALLMNLAIAVSKAVAGLLSGSAAMLSEAAHSVADTMTEVFLYIALRRGSRGPNERHPFGYGREAYFWAFMAATFTFIVGGGFSITHGFNEITADEPPGDYLVSYIVLAISFGLESVSLAKGLKQTLSESRRLKVSPWTFLKLTPDTSVKAVVLEDIAALAGLVIAGAGLGLTELTGSPVYDGVASMVIGVLLLVVAVVLAAANKSLLIGQSVPPRMRDLITEELLAVPTIKHVRELYTIHLGPSQIFVAAKVDFADTASGASIEDDSDSAERRLRQRFPQISFVFLDPTPDPPSRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2C1</accession>
    <name>D3Q2C1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkanal monooxygenase (FMN-linked)</fullName>
            <ecNumber evidence="2">1.14.14.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.14.14.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019425.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4204"/>
    <dbReference type="EnsemblBacteria" id="ADD43854">
        <property type="protein sequence ID" value="ADD43854"/>
        <property type="gene ID" value="Snas_4204"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4204"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_3_0_11"/>
    <dbReference type="OMA" id="WVDLEVF"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047646">
        <property type="term" value="F:alkanal monooxygenase (FMN-linked) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="334" mass="35604" checksum="66B98D4EFBB56945" modified="2010-04-20" version="1">MKLDLFLVGDAVHRAPHRVPAVLADYAHSAEAAGFDAVWLAEHHFIRYGACPSVPLLAAHILARTETLRVGSAACVLSNRNPVALAEEAAMLDGLSDGRFLLGVARGGPWVDLEVFGTGAERFERGFTESLDIVRHWLSGATTAASDGEFTRFRPVTVTAPPPKPPPMWVAATSRNTVDVAAERGLSLLLGVHATDEDKAAMTRRWAEVAAAAGHDPAAAEHAAVYLAYAADSRESGRRELREPLTHWLSVGVGDYLRLDGSRGSSDQEAYVDRLIDNHLVGPPDDSAERLAASVKATGISRALLLVEGRAETEAVRDNITRLGTALASANSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2E4</accession>
    <name>D3Q2E4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019448.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4228"/>
    <dbReference type="EnsemblBacteria" id="ADD43877">
        <property type="protein sequence ID" value="ADD43877"/>
        <property type="gene ID" value="Snas_4228"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4228"/>
    <dbReference type="eggNOG" id="ENOG5033FTN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1853987_0_0_11"/>
    <dbReference type="OMA" id="MTPPLAD"/>
    <dbReference type="OrthoDB" id="2095447at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="138" mass="14090" checksum="07FD581806B82540" modified="2010-04-20" version="1">MTASASPPLASIDALETLLAEPLVGRRRQRAGAVLAGVSAEVRAVAGRRWTNGAPDLAVSITLKAAERAIVNPQGLSAENLGDYGRRFGGSGPAGVYLTEGEVDALVKLTEASGVVSVPVERDVTLGGTPVSDPAVRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2U7</accession>
    <name>D3Q2U7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GHL10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6227</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021419.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6227"/>
    <dbReference type="EnsemblBacteria" id="ADD45848">
        <property type="protein sequence ID" value="ADD45848"/>
        <property type="gene ID" value="Snas_6227"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6227"/>
    <dbReference type="eggNOG" id="COG1649">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019247_2_1_11"/>
    <dbReference type="OMA" id="YGPWSEY"/>
    <dbReference type="OrthoDB" id="1573900at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003790">
        <property type="entry name" value="GHL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02638">
        <property type="entry name" value="GHL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048184" description="GHL10 domain-containing protein" evidence="3">
        <location>
            <begin position="38"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="GHL10" evidence="4">
        <location>
            <begin position="58"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="550" mass="61693" checksum="703407FAEA3FD4CE" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2X8</accession>
    <name>D3Q2X8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015519.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0229"/>
    <dbReference type="EnsemblBacteria" id="ADD39948">
        <property type="protein sequence ID" value="ADD39948"/>
        <property type="gene ID" value="Snas_0229"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0229"/>
    <dbReference type="eggNOG" id="COG3607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_21_0_11"/>
    <dbReference type="OMA" id="FMYGHGF"/>
    <dbReference type="OrthoDB" id="2035522at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="135" mass="14877" checksum="D301B5706BD18CF5" modified="2010-04-20" version="1">MSIMIFPNLPVKDLEAAKKFYTALGFELNKDFSDDNAASIVIAENIVVMLLREEFFSTFDSRTIADTATTVESVHALGVESRGKVDELVDAAIAAGGKEAGEAKDEGFMYGRAFFDLDGHHWEVMFMDLSAMPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q354</accession>
    <name>D3Q354_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0306</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015595.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0306"/>
    <dbReference type="EnsemblBacteria" id="ADD40024">
        <property type="protein sequence ID" value="ADD40024"/>
        <property type="gene ID" value="Snas_0306"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0306"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_3_3_11"/>
    <dbReference type="OMA" id="TYGDPKR"/>
    <dbReference type="OrthoDB" id="1846332at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="8"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="200"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="229" mass="25085" checksum="E38FCEA155FE73F6" modified="2010-04-20" version="1">MPVTHAFFSVTVDLVVLTVQRETLSVLLIKRAFDPFKDSLALPGGFVTEGEDLMAAASRELAEETGLSTAEGHLEQLATYGTPDRDPRGRVVTVAYLALLPDLPAPRAGSDAAAAAWHPVPSLLDKEDVLAFDHHRILCDGVERARAKLEYSSLAAEFCPPEFTIAQLRRIYEAVWGATVDPRNFHRKVTGTPGFVVATDNYTDGDRGRPARLYRRGPASSLHPPLLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q373</accession>
    <name>D3Q373_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40043">
        <property type="protein sequence ID" value="ADD40043"/>
        <property type="gene ID" value="Snas_0325"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0325"/>
    <dbReference type="HOGENOM" id="CLU_3258160_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="42" mass="4873" checksum="CD6685037B2F78DC" modified="2010-04-20" version="1">MGKHDKKPDPSGNGHKPKDKVDPKKFVKPEDVKHKHDRKDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3D7</accession>
    <name>D3Q3D7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2289</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017549.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2289"/>
    <dbReference type="EnsemblBacteria" id="ADD41978">
        <property type="protein sequence ID" value="ADD41978"/>
        <property type="gene ID" value="Snas_2289"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2289"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_11"/>
    <dbReference type="OMA" id="HHGHESL"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040582">
        <property type="entry name" value="OB_MalK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17912">
        <property type="entry name" value="OB_MalK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="391" mass="43629" checksum="D7CE5945B1798F73" modified="2010-04-20" version="1">MTTVELKNVSKVFAPDIVAVDDLNLSVNNGEFMVLLGPSGCGKSTILRMLAGLEDTLDGDILLNGEFANHLTPRERGVAMVFQNFALYPHFRVADNIGFPLRIAGVDAATIKERTVAMAASLGIEDLLDRKPHQLSGGQRQRVAMGRALIRHPRFLLMDEPLSNLDIGLRSQLRTEIVEMAHRLNITTVYVTHDQTEALTMADRVAVLRRGRLQDVGSPDQVYDKPATMYVAAFLGNPRMNLVRAYVEVHLDRYVTLHLGSQSIRLPWSDLQSRGVSKYHGEQIVVGIRAEAVRPVSHDRPNVLNGLIQFMEHHGHESLVHLRIGAVPVDHDAHSQQPESGRHNKQISDVTVRLAPYSRCRPGQAMSIEVHTDLLHFFDSNGNRIEAVQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3L9</accession>
    <name>D3Q3L9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017631.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2375"/>
    <dbReference type="EnsemblBacteria" id="ADD42060">
        <property type="protein sequence ID" value="ADD42060"/>
        <property type="gene ID" value="Snas_2375"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2375"/>
    <dbReference type="eggNOG" id="COG2388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132888_0_0_11"/>
    <dbReference type="OMA" id="IVPVCSM"/>
    <dbReference type="OrthoDB" id="1872172at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045057">
        <property type="entry name" value="Gcn5-rel_NAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031165">
        <property type="entry name" value="GNAT_YJDJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31435">
        <property type="entry name" value="PTHR31435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14542">
        <property type="entry name" value="Acetyltransf_CG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51729">
        <property type="entry name" value="GNAT_YJDJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="94" mass="11041" checksum="6C3FA295DBA96FAA" modified="2010-04-20" version="1">MSVQIVDNPDRSRYEAQEDGTVVAYVEYDRHEDFTAFPHTEVSRDHRGQGLAGMLVRQAMDDIRESGDKAYPLCPYVKEWFTKHPEYEDIIYRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Q3</accession>
    <name>D3Q3Q3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4323</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019541.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43970">
        <property type="protein sequence ID" value="ADD43970"/>
        <property type="gene ID" value="Snas_4323"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4323"/>
    <dbReference type="HOGENOM" id="CLU_993620_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032724">
        <property type="entry name" value="DddA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14428">
        <property type="entry name" value="SCP1201-deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="243" mass="26634" checksum="F7044073EEE80F81" modified="2010-04-20" version="1">MSMLRRLVAALRAARTRTVETRDKIIAAKSRSDAGLLAFQQATNGSIDSRPAEAIANLQRAKTHLDEAQRLVANSDAAVDNYINAILGGASAATAQPSAVIPASKPSRFKPMRTDPAKADEIRPHVGKDRAVATLWDADGNRVLGLHSADDDGPAATAAWKPPWRDYVRLRRHVEAHAAARMHQDGHKTMVMYINLPPCKYFDGCKLNLEDILPKGSTLWMHRVFQNGGTKIYQFNGTGRAYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3R4</accession>
    <name>D3Q3R4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019552.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4334"/>
    <dbReference type="ESTHER" id="stanl-d3q3r4">
        <property type="family name" value="Haloacetate_dehalogenase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43981">
        <property type="protein sequence ID" value="ADD43981"/>
        <property type="gene ID" value="Snas_4334"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4334"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_1_11"/>
    <dbReference type="OMA" id="LSFCEML"/>
    <dbReference type="OrthoDB" id="1439833at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="20"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="278" mass="31371" checksum="038DBA9EB11F0C2C" modified="2010-04-20" version="1">MAVANVNGLRMHYETAGEGPPLVLLHGWPQTRHCWRKVAPRLAERYTVITPDLRGYGRTDKPTSGYDKRTMAADVSGLLRSLGFGSAAVVGHDRGARVAHRWGLDRPEEVERLVVLDIVPTREMWRAGAVVASGYWHWMFHLQPDLPELLAGKDIGAYLGHFFEQWTFDRGGLEAEAIAEYVRAFSVPGALRAGFDDYRASFPYDAEADDADHEAGRRLTMPMLALWGSQGLPRNFDVLDVWKRYAENVRGEAIPDCGHFVAEERPEALLERLREFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Z8</accession>
    <name>D3Q3Z8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021454.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6263"/>
    <dbReference type="EnsemblBacteria" id="ADD45883">
        <property type="protein sequence ID" value="ADD45883"/>
        <property type="gene ID" value="Snas_6263"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6263"/>
    <dbReference type="HOGENOM" id="CLU_2411758_0_0_11"/>
    <dbReference type="OrthoDB" id="2095270at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="92" mass="10550" checksum="176528F808CC2EF2" modified="2010-04-20" version="1">MNNTLSRFGSDILGKCCWARDYNDGHPNPAWSTGEKLAVALVLDDKEFLNAEDYTIPEAKQRVFSGSWEWRDKAHFDDWLVQLRALLDTSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Z9</accession>
    <name>D3Q3Z9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6264</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6264"/>
    <dbReference type="EnsemblBacteria" id="ADD45884">
        <property type="protein sequence ID" value="ADD45884"/>
        <property type="gene ID" value="Snas_6264"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6264"/>
    <dbReference type="HOGENOM" id="CLU_145372_2_0_11"/>
    <dbReference type="OMA" id="CHADMLL"/>
    <dbReference type="OrthoDB" id="1578245at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025475">
        <property type="entry name" value="DUF4326"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14216">
        <property type="entry name" value="DUF4326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="89" mass="9734" checksum="FFAD9D1C72E7E582" modified="2010-04-20" version="1">MPPNTVYVGRPSRFANPFPITGGNAKVAVAYFRNHLAARPDLAADIRAQLVGRNLACWCARFDTAGLRVLCHADMLLVVAKGWGLHDFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4C0</accession>
    <name>D3Q4C0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">bPH_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015651.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0362"/>
    <dbReference type="EnsemblBacteria" id="ADD40080">
        <property type="protein sequence ID" value="ADD40080"/>
        <property type="gene ID" value="Snas_0362"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0362"/>
    <dbReference type="eggNOG" id="ENOG5031NQU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143522_0_0_11"/>
    <dbReference type="OMA" id="LIHAVFD"/>
    <dbReference type="OrthoDB" id="1682253at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012544">
        <property type="entry name" value="PHb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037063">
        <property type="entry name" value="PHb_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08000">
        <property type="entry name" value="bPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="bPH_1" evidence="1">
        <location>
            <begin position="9"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="121" mass="13528" checksum="0141D2D99587E484" modified="2010-04-20" version="1">MAEVVYDKKDQLKQIEELLLNGEQVIAVYDAIGVGTGFIGLTDKRVILKNKSFVGKKVALTSIPYAKISAVSLTSNKSFAGQWFSSGEMAIHAGKEIHEIEFRGDRKTHHVHQVIMHYITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4I7</accession>
    <name>D3Q4I7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015718.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0431"/>
    <dbReference type="EnsemblBacteria" id="ADD40147">
        <property type="protein sequence ID" value="ADD40147"/>
        <property type="gene ID" value="Snas_0431"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0431"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_59_0_11"/>
    <dbReference type="OMA" id="PFELACA"/>
    <dbReference type="OrthoDB" id="1459004at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="214"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="320" mass="34643" checksum="6B41550A5296E936" modified="2010-04-20" version="1">MKRHRVVALVNEPQSPFELASAAEVFGGVRPDVPRHYDFRVCAEHPGPVATTVGYPMLVDAGLAALRRADTVVIPGWQPHDAPVSAAIIAALRSAHRRGARIAAICTGAFVLARTGLLDGRRATTHWRHTAELAADFPELRVDRDVLFVDHGDVATSAGTGAGIDLCLHLVRSDHGAAYAAQIALNMVLPPHREGSQLQYATRPAPVRADESLAPVLEWASTRLHNRLTVGRLAEQAGLSERTLARRFAEQLGVSPGQWLLGQRLDAARVLLESSDLPVDAIVTRVGLASAVNLRRRFRSRFGTTPGGYRRAFGEGRRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4P6</accession>
    <name>D3Q4P6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Betaine-aldehyde dehydrogenase</fullName>
            <ecNumber evidence="6">1.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2393</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017647.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2393"/>
    <dbReference type="EnsemblBacteria" id="ADD42076">
        <property type="protein sequence ID" value="ADD42076"/>
        <property type="gene ID" value="Snas_2393"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2393"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_0_11"/>
    <dbReference type="OMA" id="KHIWHNT"/>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008802">
        <property type="term" value="F:betaine-aldehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="23"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="501" mass="52856" checksum="F652C2835A61A006" modified="2010-04-20" version="1">MSDHAPLPGQPQTLLFIGGRWTPAVAGGTRDIIDPTTGTAITAVAEADAADVAEAIAAAREAFDGGPWPHTSAAERGAILQTVARLLQRDKQAIAELESRDTGKTLREGLIDVDDVTAVFRYYGELADKDLGRVVDTGNPDAQSRVVAEPVGVCSLIAPWNYPLLQMSWKLAPALAAGNTVVAKPSEVTPLTTLKLVDLLTEAGVPSGVVNLVLGAGDPVGQTMVESDRVDLVSFTGGLVSGRRVAATAAATVKKVALELGGKNPNVVFADADFDAAVDGAVNAAFVHSGQVCSAGTRLILHTDIYDDFLAAVAARADAITLGPGMDPASECGPLVSAAQRDKTETYVAGALAQGARLLAGGRRPDDPALADGYYYRPTVFADCHREMTVVREETFGPILTAERFATEDEAIFLANDTIYGLAGAVWTSDAGRGERIAARLRHGTVWINDFHPYLPQAEWGGFKASGIGRELGVSGLNEYRELKHIYRNINPKPSGWFAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Q3</accession>
    <name>D3Q4Q3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histidine triad (HIT) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2400"/>
    <dbReference type="EnsemblBacteria" id="ADD42083">
        <property type="protein sequence ID" value="ADD42083"/>
        <property type="gene ID" value="Snas_2400"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2400"/>
    <dbReference type="eggNOG" id="COG0537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056776_1_2_11"/>
    <dbReference type="OMA" id="YNPGHVM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01275">
        <property type="entry name" value="FHIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039383">
        <property type="entry name" value="FHIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="46"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="3">
        <location>
            <begin position="140"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="2">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR639383-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="183" mass="19577" checksum="7EB0F9E4150757BD" modified="2010-04-20" version="1">MNDDGAQPGGLGIPDGLERLWTPHRMAYIKGEGKPTGTDEDPVGCPFCEMPKLGDEEGLIVARGALAFCVLNLYPYNSGHLMVCPYRHVADYTDLDDAEVAEVGAMTQQAMRVIRSVSGAHGFNIGLNQGRVAGAGIAGHLHQHVVPRWGGDGNFMPIIARTRVLPELLTDTRDLLSGAWGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Y5</accession>
    <name>D3Q4Y5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2482</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017736.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2482"/>
    <dbReference type="EnsemblBacteria" id="ADD42165">
        <property type="protein sequence ID" value="ADD42165"/>
        <property type="gene ID" value="Snas_2482"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2482"/>
    <dbReference type="eggNOG" id="COG2020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065200_4_1_11"/>
    <dbReference type="OMA" id="VRNPMYV"/>
    <dbReference type="OrthoDB" id="1734625at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="169" mass="18575" checksum="B0790AA104E57880" modified="2010-04-20" version="1">MRKRSAAIGSTIFFVLGPGTVAGLVPWLITGWESTDMPGWWWALRGLGAMCVLAGVAVIAHAFYRFVVEGLGTPVPAAPPSHLVVGGLFRHVRNPMYVALALMTGGQTLVFASWPLAIYFAAAWACTAAFVKVYEEPKLTSRFGEEYRTYKRHVPAWIPRIRPWTPTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Z4</accession>
    <name>D3Q4Z4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane-flanked domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017745.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2491"/>
    <dbReference type="EnsemblBacteria" id="ADD42174">
        <property type="protein sequence ID" value="ADD42174"/>
        <property type="gene ID" value="Snas_2491"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2491"/>
    <dbReference type="eggNOG" id="COG3402">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104197_0_0_11"/>
    <dbReference type="OMA" id="PYGRMQY"/>
    <dbReference type="OrthoDB" id="1768296at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="79"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="167" mass="18271" checksum="7F2A297E7F746415" modified="2010-04-20" version="1">MPESASVWSSWPGEVTWHPVAPQYLKVRLVSLALFGVVALAAVLIAPWLWWGRTWALLLGGVVLAGLLVRAVLLRRAVRAWGYAERDDDLLIRHGVLIKRLSIVPYGRMQFIDVSAGPVDRMFDLATVKLHTAAATTDSTVPGLAPDVATGLRDRLAQRATAEREGL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-08-10" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q568</accession>
    <name>ARC_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Proteasome-associated ATPase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">AAA ATPase forming ring-shaped complexes</fullName>
            <shortName evidence="1">ARC</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Proteasomal ATPase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">arc</name>
        <name type="ordered locus">Snas_4472</name>
    </gene>
    <organism>
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein degradation; proteasomal Pup-dependent pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer. Assembles into a hexameric ring structure that caps the 20S proteasome core. Strongly interacts with the prokaryotic ubiquitin-like protein Pup through a hydrophobic interface; the interacting region of ARC lies in its N-terminal coiled-coil domain. There is one Pup binding site per ARC hexamer ring. Upon ATP-binding, the C-terminus of ARC interacts with the alpha-rings of the proteasome core, possibly by binding to the intersubunit pockets.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of three main regions, an N-terminal coiled-coil domain that binds to protein Pup and functions as a docking station, an interdomain involved in ARC hexamerization, and a C-terminal ATPase domain of the AAA type.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019688.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D3Q568"/>
    <dbReference type="SMR" id="D3Q568"/>
    <dbReference type="STRING" id="446470.Snas_4472"/>
    <dbReference type="EnsemblBacteria" id="ADD44117">
        <property type="protein sequence ID" value="ADD44117"/>
        <property type="gene ID" value="Snas_4472"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4472"/>
    <dbReference type="eggNOG" id="COG1222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036054_0_0_11"/>
    <dbReference type="OMA" id="CVDEFKE"/>
    <dbReference type="OrthoDB" id="1115436at2"/>
    <dbReference type="UniPathway" id="UPA00997"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019941">
        <property type="term" value="P:modification-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02112">
        <property type="entry name" value="ARC_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041626">
        <property type="entry name" value="Prot_ATP_ID_OB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022482">
        <property type="entry name" value="Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17758">
        <property type="entry name" value="Prot_ATP_OB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03689">
        <property type="entry name" value="pup_AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0175">Coiled coil</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0647">Proteasome</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000397021" description="Proteasome-associated ATPase">
        <location>
            <begin position="1"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Docks into pockets in the proteasome alpha-ring" evidence="1">
        <location>
            <begin position="595"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="12"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="280"/>
            <end position="285"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02112"/>
        </source>
    </evidence>
    <sequence length="596" mass="66697" checksum="DF2772EA9EA996B5" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q574</accession>
    <name>D3Q574_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4478</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4478"/>
    <dbReference type="EnsemblBacteria" id="ADD44123">
        <property type="protein sequence ID" value="ADD44123"/>
        <property type="gene ID" value="Snas_4478"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4478"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="YRVYARI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="300"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="400" mass="43573" checksum="CBAF077559DC5CF6" modified="2010-04-20" version="1">MRNGPLHRWFQARPLAGDSLLALIVFGLSGLAFLAPEIKPTDPLIWLWLFLGSLPVAIRRVWLWWSLALTIALLFASMLDPLAWLSGTWAILVIAYTIAAALPFRNAIAATAALWGVATLTIVMARPEQLAQSPAFVVLMFNYVLAVTCFGIGRVVHGKRVKVSELEDRARIAEENQVAKVVEAINDERRRIARELHDVVAHHLSVMNVMATGARRTLTSDPDRADEALATIESTGRTTLREMRRLLEVLRTDDEPAVDDRELTPQPGLDAIHTLVGQVRSAGLPVKLVIDGTPFPLDQGIALTAFRIIQEGLTNTLKHGGPANSGVRISYREDELEIEVTDNGAGQKSLTTASGRVGHGLVGMRERVALYGGSLRTGPRPGGGFRVHALIPIEAPTETT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q583</accession>
    <name>D3Q583_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Smr protein/MutS2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019703.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4487"/>
    <dbReference type="EnsemblBacteria" id="ADD44132">
        <property type="protein sequence ID" value="ADD44132"/>
        <property type="gene ID" value="Snas_4487"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4487"/>
    <dbReference type="eggNOG" id="COG1193">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2467710_0_0_11"/>
    <dbReference type="OMA" id="DIFNKGH"/>
    <dbReference type="OrthoDB" id="1888882at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01713">
        <property type="entry name" value="Smr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SSF160443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Smr" evidence="1">
        <location>
            <begin position="6"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="94" mass="10953" checksum="49342EC5DF1C7464" modified="2010-04-20" version="1">MAKLVLDLHDIYNKGDLIDKALRDIINEAVDKKIATVEIIPGKGSGQLKKKVIRFLEQKDIKAMYHRIDKDSKNFGRLFVYFQHKADKGKKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5E2</accession>
    <name>D3Q5E2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell envelope-related transcriptional attenuator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6386</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6386"/>
    <dbReference type="EnsemblBacteria" id="ADD46002">
        <property type="protein sequence ID" value="ADD46002"/>
        <property type="gene ID" value="Snas_6386"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6386"/>
    <dbReference type="eggNOG" id="COG1316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016455_0_2_11"/>
    <dbReference type="OMA" id="METIMLP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="4">
        <location>
            <begin position="119"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD46002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="382" mass="40986" checksum="A6721253BFC95E39" modified="2010-04-20" version="1">MSSYRSGSDRPRASARVPSGPRATGGHQYSGKTYGGGGGPRVKPPTNTARMVVLTCLVVSLIFTLGGIGAWGYAKSLNSGLDRFDAFDGVSDRPEDDDGLNILVLGSDSRNPDSTKDSRADTIMIAHVPSNGEKAYMISLPRDLWVNVPAAGDWGGGKNKLNSASFFGGVPLMVQTVEGYTDVHIDHVIEIDFNGLIKVVDALGGVTMNVEEADAPDYATPGKLTSIHKYKGKEPRTWKAGKQTLDGESALDYVRQRKQFNEGDFARMRHQRELLKAMMDKATSAGIITSPGSLTDFLSSVTDAVKVDKEFDLISTGVSLSSLRSKDLVFMVSPNIPNGYDEATGQSIVESDKEKASALYKAIAADDMASWAKDHPKDVKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5H1</accession>
    <name>D3Q5H1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Propionyl-CoA carboxylase</fullName>
            <ecNumber evidence="3">6.4.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.4.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6415"/>
    <dbReference type="EnsemblBacteria" id="ADD46031">
        <property type="protein sequence ID" value="ADD46031"/>
        <property type="gene ID" value="Snas_6415"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6415"/>
    <dbReference type="eggNOG" id="COG4799">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018822_6_1_11"/>
    <dbReference type="OMA" id="PQVCALF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004658">
        <property type="term" value="F:propionyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045190">
        <property type="entry name" value="MCCB/AccD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855">
        <property type="entry name" value="PTHR22855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="2">
        <location>
            <begin position="254"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD46031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="506" mass="54391" checksum="05FB5E8F8A9CEB98" modified="2010-04-20" version="1">MPVDTRKLRSEIASGGASKYHEANAAKGKLFARERIARLVDPDSFVEDGYFANAMAEGLPADGVVTGTARINGRPVCLLANDSTVKAGSWGARTVEKMVRITDRAYERGVPMVYLVDSAGARITDQVELFPGRRGAGRIFYNQVRASGSIPQVCALFGPSAAGGAYVPAFCDVVAMVDKNSSMYLGSDRMVEMVTGEKTTLEDMGGAKVHCTESGVGHFLCKDEDEALDVVKDYLSYLPDNWTAQPPAVEPAPAPGTDLRAMVPASERQAFDMRKYAKGILDEGSFFEIQARWAKELVTGFGRLNGETVGVVANNSMFKGGVLFVDSADKASRFVQLCDAFNVPLLFLADVPGFMVGSAVEKQGIIRHGAKMVSAVSEATVPKICVVVRKAYGAGLYAMAGPGFGPDATLALPTAKIAVMGAEAAVNAVYARKIAAIEDEDERAEFVDTKRTEYEADIDIVRLASELVIDDIVEPESLRDDLIARYAALRGKDRSFSRRRHGVTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5I2</accession>
    <name>D3Q5I2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="3">6.3.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">D-Ala-D-Ala ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">D-alanylalanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ddl</name>
        <name evidence="7" type="ordered locus">Snas_6426</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="4">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021613.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6426"/>
    <dbReference type="EnsemblBacteria" id="ADD46042">
        <property type="protein sequence ID" value="ADD46042"/>
        <property type="gene ID" value="Snas_6426"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6426"/>
    <dbReference type="eggNOG" id="COG1181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039268_1_0_11"/>
    <dbReference type="OMA" id="MQGLLEC"/>
    <dbReference type="OrthoDB" id="764798at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011127">
        <property type="entry name" value="Dala_Dala_lig_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01820">
        <property type="entry name" value="Dala_Dala_lig_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2 3" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="103"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR039102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD46042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="317" mass="33201" checksum="A356879F9F7E1C7F" modified="2010-04-20" version="1">MRQDARVLVLAGGLSYEREVSLRSGRRVADALSRANVHAELRDVDTNLLPDLIADPPDAVVFALHGGNGEDGSLRSVLDLIGIPYVGPDADAARRAWDKPTAKALLRDAGLPTPEWIALPRETFSDLGAAKLLDRIVDKLGVPLAVKPARGGSGLGVAVVRTAEELPAAMIGCFAYGDVALVEAFAPGKDIAVGVVDTGDGPRVFPAVEIEPSGDAYDFAARYNPGASTWHVPARLAPRVSEDVAAVATAAFRTLGLRDLSRIDMMVPQAGPPLVLEAKVVPGMTETSLLPMACEAAGHDLGELMAGLVDRAIARAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5L2</accession>
    <name>D3Q5L2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6457</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021643.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6457"/>
    <dbReference type="EnsemblBacteria" id="ADD46072">
        <property type="protein sequence ID" value="ADD46072"/>
        <property type="gene ID" value="Snas_6457"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6457"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_11"/>
    <dbReference type="OMA" id="PEIWKRE"/>
    <dbReference type="OrthoDB" id="1094766at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD46072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="252" mass="26052" checksum="6CB496831F0F6E96" modified="2010-04-20" version="1">MSKPRTALVTGAGRGIGRVVAQRLSSAGYRVVLTARSRDQLEATASECPEQTLVVPADLTADGAVDGLFAEAESGFGPVDVLVLNAGAGSSAPLPRVTDTDWQQQLDLNLTAPFRCLRRAVPTMRQRSWGRVVAVASVASKRGEPYIAAYTAAKHGLLGLVRSAAAELAGTGVTVNAVCPGYVDTPMTEASVANIAARTGTDAAEARELLERKQPIGRLIAPEEVADAIMLCVNSSGITGQGINVDGGAIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5L5</accession>
    <name>D3Q5L5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein</fullName>
            <shortName evidence="2">P2TMN nickel insertion protein</shortName>
            <ecNumber evidence="2">4.99.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Nickel-pincer cofactor biosynthesis protein LarC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">larC</name>
        <name evidence="3" type="ordered locus">Snas_6460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Ni(II)-pyridinium-3,5-bisthiocarboxylate mononucleotide = Ni(2+) + pyridinium-3,5-bisthiocarboxylate mononucleotide</text>
            <dbReference type="Rhea" id="RHEA:54784"/>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <dbReference type="ChEBI" id="CHEBI:137372"/>
            <dbReference type="ChEBI" id="CHEBI:137373"/>
            <dbReference type="EC" id="4.99.1.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LarC family.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.12" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021646.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6460"/>
    <dbReference type="EnsemblBacteria" id="ADD46075">
        <property type="protein sequence ID" value="ADD46075"/>
        <property type="gene ID" value="Snas_6460"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6460"/>
    <dbReference type="eggNOG" id="COG1641">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028523_2_1_11"/>
    <dbReference type="OMA" id="TCLGLDW"/>
    <dbReference type="OrthoDB" id="1547060at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01074">
        <property type="entry name" value="LarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002822">
        <property type="entry name" value="Ni_insertion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36566">
        <property type="entry name" value="PTHR36566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01969">
        <property type="entry name" value="DUF111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00299">
        <property type="entry name" value="TIGR00299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 2" id="KW-0533">Nickel</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD46075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="414" mass="42727" checksum="ACC13368F0685C97" modified="2010-04-20" version="1">MICWIDAAAGASGDMFLGALVDAGVPLEVLRASVDALGVEPVRLTATETTRHGLAATKVDVDCPQSTIDRRYASIVRLITEASLPQPVRDKAIDVFTRLGHAEAAAHRVRLDDVHFHEVGALDSLADVVAACAGLHWLAENRGLGRIVCSAVTAGGGVTRGAHGGIPLPAPATLAVLSRAKAPVAGEVSYEACTPTGAAIIAAHATAYGTMPLMTVDAVGVGAGGRDPAERANVLRLVLGSQPTRADHAHSHGHHHAAPTVAAGDRPSALVMEANVDDLDPRLWPQVLAALLAAGASDAWLTPILMKKGRPAHTLSVLCGHDVEARVRSAIFAHTSTIGLRVNEVGKHALDREYGSIVLDGQTIGVKLARDDGRIVNVSVEHADVEAAATALDLPVKVVLARASGLAAESYGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5N1</accession>
    <name>D3Q5N1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FHA domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6476</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021662.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6476"/>
    <dbReference type="EnsemblBacteria" id="ADD46091">
        <property type="protein sequence ID" value="ADD46091"/>
        <property type="gene ID" value="Snas_6476"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6476"/>
    <dbReference type="eggNOG" id="COG1716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131367_0_0_11"/>
    <dbReference type="OMA" id="GQWIVED"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="4">
        <location>
            <begin position="86"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD46091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="158" mass="16903" checksum="E16709FBC7E6D1FA" modified="2010-04-20" version="1">MPELVFTIARFGLLFLLWLFVFVVARTIRRDVFAGTAARTPARVPGRGNASRRGGGITSGPRPPRQLVVTEGELAGTQLPLGNAPIRIGRAPDSTLVITDDYASGRHAQLVPRGDQWLVEDLGSTNGTYLGRAKVSGPTPIPAGVPIRIGRTSIELRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5S4</accession>
    <name>D3Q5S4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helicase_C_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0508</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015794.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0508"/>
    <dbReference type="EnsemblBacteria" id="ADD40223">
        <property type="protein sequence ID" value="ADD40223"/>
        <property type="gene ID" value="Snas_0508"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0508"/>
    <dbReference type="eggNOG" id="COG2378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013420_0_0_11"/>
    <dbReference type="OMA" id="WGPPYGQ"/>
    <dbReference type="OrthoDB" id="1388804at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032830">
        <property type="entry name" value="XPB/Ssl2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13625">
        <property type="entry name" value="Helicase_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase_C_3" evidence="3">
        <location>
            <begin position="483"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="759" mass="81438" checksum="4C68E443ACFFDFC3" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q609</accession>
    <name>D3Q609_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015879.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0594"/>
    <dbReference type="EnsemblBacteria" id="ADD40308">
        <property type="protein sequence ID" value="ADD40308"/>
        <property type="gene ID" value="Snas_0594"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0594"/>
    <dbReference type="eggNOG" id="COG1408">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025443_4_0_11"/>
    <dbReference type="OMA" id="PVRFACP"/>
    <dbReference type="OrthoDB" id="1690667at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="49"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="296" mass="32044" checksum="5A5554C3E9DE3D02" modified="2010-04-20" version="1">MKKRSLIATAGVLAAGGAAALAYASLIERFRFQLRRFDVPVLAPDTEPLRILHISDLHLSPNSHKEVEWVASLAALDPDLVVLTGDNLAHPEAVSTVSAALEPLFTYPGVFVFGSNDYYAPVLKNPFTYFNPNREHKYGEELPTEELRKMLTGAGWRDLNNATTTIPIADRTIAVAGVDDPHFDLDDYDLIAGEAPTDASVTLGLTHSPEPRVLDQMAADGYQLLLAGHTHGGQVCVPGYGALVTNCGIDRKRVKGLHRYGSSWLHVSAGLGTSPYAPIRFACHPEASILTLIPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q648</accession>
    <name>D3Q648_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xanthine dehydrogenase D subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2542</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2542"/>
    <dbReference type="EnsemblBacteria" id="ADD42223">
        <property type="protein sequence ID" value="ADD42223"/>
        <property type="gene ID" value="Snas_2542"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2542"/>
    <dbReference type="eggNOG" id="COG1529">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001681_2_3_11"/>
    <dbReference type="OMA" id="THYYQTV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017609">
        <property type="entry name" value="Xanthine_dehydrogenase_dsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03196">
        <property type="entry name" value="pucD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="2">
        <location>
            <begin position="49"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="781" mass="83241" checksum="ADBD8476F1D75368" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q687</accession>
    <name>D3Q687_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017833.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2582"/>
    <dbReference type="EnsemblBacteria" id="ADD42262">
        <property type="protein sequence ID" value="ADD42262"/>
        <property type="gene ID" value="Snas_2582"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2582"/>
    <dbReference type="eggNOG" id="COG0637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_12_1_11"/>
    <dbReference type="OMA" id="TMGESKI"/>
    <dbReference type="OrthoDB" id="1484726at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="224" mass="23124" checksum="B2DEAB49F37EB77D" modified="2010-04-20" version="1">MNRISLVCADMAGTTVSDGGIVEQAASVALEECGIPAGSSGHDSAMSYIRQTMGQSKIEVFRAVTSDEDTAQLANASFERNISALATDGRITALPHAVDALKALRDKGIKIALTTGFAPATQDAILRALDWETLIDLAVAPGKELRGRPNPDMVLHAVLRLGIDDVREVAVVGDSVNDVYSGLRAGASVVAGVTTGSHDANALRKAGATHVLDDIGQLPGLVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6A4</accession>
    <name>D3Q6A4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Phosphoribosyl-ATP pyrophosphatase</fullName>
            <shortName evidence="10">PRA-PH</shortName>
            <ecNumber evidence="3 10">3.6.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hisE</name>
        <name evidence="11" type="ordered locus">Snas_2600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the PRA-PH family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.31" evidence="3 10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017850.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2600"/>
    <dbReference type="EnsemblBacteria" id="ADD42279">
        <property type="protein sequence ID" value="ADD42279"/>
        <property type="gene ID" value="Snas_2600"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2600"/>
    <dbReference type="eggNOG" id="COG0140">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123337_2_1_11"/>
    <dbReference type="OMA" id="WMAAEYQ"/>
    <dbReference type="OrthoDB" id="2022633at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01020">
        <property type="entry name" value="HisE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD42279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="87" mass="9480" checksum="1632D3478C5017F3" modified="2010-04-20" version="1">MKSFEQLFAELSAKAEARPAGSGTVAALDAGVHTIGKKVVEEAAEVWMAAEHEGRERTAEEISQLLYHLQVLMLATGLSLDDIYKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6G9</accession>
    <name>D3Q6G9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4568</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019783.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4568"/>
    <dbReference type="EnsemblBacteria" id="ADD44212">
        <property type="protein sequence ID" value="ADD44212"/>
        <property type="gene ID" value="Snas_4568"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4568"/>
    <dbReference type="eggNOG" id="COG3801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_138549_1_1_11"/>
    <dbReference type="OMA" id="DWRVGKK"/>
    <dbReference type="OrthoDB" id="1817663at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007351">
        <property type="entry name" value="YjbR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038056">
        <property type="entry name" value="YjbR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04237">
        <property type="entry name" value="YjbR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142906">
        <property type="entry name" value="SSF142906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="134" mass="15114" checksum="58C7062DA1EF8992" modified="2010-04-20" version="1">MATWDDVRRIAMALPETTERSSYDGTAAWRVKDKLFVWERPLRGTDREALGESAPDGPILAARVADLGEREALIEQDPKVYFTIPHFDGYPAILIHLDNIDVAELTEVVTDAWFTRAPKRVASQFRAREAESQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6I0</accession>
    <name>D3Q6I0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromate transporter, chromate ion transporter (CHR) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_4579</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019794.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4579"/>
    <dbReference type="EnsemblBacteria" id="ADD44223">
        <property type="protein sequence ID" value="ADD44223"/>
        <property type="gene ID" value="Snas_4579"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4579"/>
    <dbReference type="eggNOG" id="COG2059">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018106_0_0_11"/>
    <dbReference type="OMA" id="YQGAVGH"/>
    <dbReference type="OrthoDB" id="1884249at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014047">
        <property type="entry name" value="Chr_Tranpt_l_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004810">
        <property type="entry name" value="ChrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00937">
        <property type="entry name" value="2A51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="379" mass="40093" checksum="16DADE5B74FE5524" modified="2010-04-20" version="1">MSAGSVREVAGVFLRLGTIAFGGPAAHTAMMREELVRRRGWVSDQRFVDLMGATNFIPGPNSTELAIHLGHDRARWKGLVAAGVCFILPAAVMVTGLAWAYVTYGQTPAVKGVLYGVVPAVIGIIAHALFGLLRTVVKTVWLGALGVAALVAYFLGVNELVILAAGGLLAVAVHFGQRWRGSVSGFAIPLLWTDKLPVFADPTTGQLAQLFATMLKIGAVLYGSGYVLLAFLRGDFVDRLHWISNEQLIDAVSIGQVTPGPVFTTATFVGYLVAGLPGAFLATVAIFLPSFVFVGLLTKLTGWLRSRDWTAMLLDGVNATALALMAGVSFQLGRTAIIDPLTAAIAIVTVLLLWRTKLNSAWYIAGGAVIGVAHILLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6J6</accession>
    <name>D3Q6J6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4595"/>
    <dbReference type="EnsemblBacteria" id="ADD44239">
        <property type="protein sequence ID" value="ADD44239"/>
        <property type="gene ID" value="Snas_4595"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4595"/>
    <dbReference type="eggNOG" id="ENOG50339BQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1128511_0_0_11"/>
    <dbReference type="OrthoDB" id="1991436at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="207" mass="22055" checksum="3B24D71D0797F8A6" modified="2010-04-20" version="1">MQNPKRPRGYEDRLLSELKTYVSERNQTMTTIEETPAKTPRFGRAAKFSFAGAVGAVALGVGAVVALPALTASPAYAVEDTKGGNVRVQVNSPDDAAGLEEALAEHGIKAKVDFPPIGYVCDWERYEPAVVDDNGEGEAIELGETDEGEPFAAFEVNPDNYSLDGDITLVVEISEGAFDKDAENVMVTGLEAAKGEVGECDPVKDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6V8</accession>
    <name>D3Q6V8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0644"/>
    <dbReference type="EnsemblBacteria" id="ADD40357">
        <property type="protein sequence ID" value="ADD40357"/>
        <property type="gene ID" value="Snas_0644"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0644"/>
    <dbReference type="HOGENOM" id="CLU_1502577_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="179" mass="19229" checksum="C5C01B3F03DF4B62" modified="2010-04-20" version="1">MDPEGAEGRSNAVSLTWGCILGLVVGFGCLLGGSIGAVEGSPEQEPGGNVVFIILGGLLAIGSIILLVIAIKSWRRLRRTLSLDATWIRVASAGEQASFQWAEVSKVTVSRVFVYLTIPSASKHDAERFSNLASDRSVWKPESPRVILCKLDSLTGSRQSFLDALTRLSGHDIEYPSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q741</accession>
    <name>D3Q741_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Uracil-DNA glycosylase</fullName>
            <shortName evidence="8">UDG</shortName>
            <ecNumber evidence="4 8">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ung</name>
        <name evidence="12" type="ordered locus">Snas_0728</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="4 8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0728"/>
    <dbReference type="EnsemblBacteria" id="ADD40440">
        <property type="protein sequence ID" value="ADD40440"/>
        <property type="gene ID" value="Snas_0728"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0728"/>
    <dbReference type="eggNOG" id="COG0692">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032162_3_1_11"/>
    <dbReference type="OMA" id="WEAVTEQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="PTHR11264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="11">
        <location>
            <begin position="60"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD40440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="238" mass="25708" checksum="56F7045341B5B120" modified="2010-04-20" version="1">MPTTKLSLVGQPLDEIVEKGWAKALAPVADKIAEMGDFLRAEVAAGRKYLPAGENVLRAFKQPFDEVKVLIVGQDPYPTPGHPIGLSFAVAPDVRPLPKSLVNIFNEYKSDLGFPLPTNGDLTPWTNEGVLLLNRALSVAPGAPASHRGKGWEEVTEQAIKALAQRGSPLVAILWGRDARNLRPMLGELPCIESPHPSPLSARSGFFGSRPFSRANELLTEQGAEPVNWRLPSPEDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q744</accession>
    <name>D3Q744_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoenolpyruvate carboxykinase [GTP]</fullName>
            <shortName evidence="8">PEP carboxykinase</shortName>
            <shortName evidence="8">PEPCK</shortName>
            <ecNumber evidence="8">4.1.1.32</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GTP-dependent phosphoenolpyruvate carboxykinase</fullName>
            <shortName evidence="8">GTP-PEPCK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pckG</name>
        <name evidence="11" type="ordered locus">Snas_0731</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + oxaloacetate = CO2 + GDP + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10388"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.32"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.32" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016014.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0731"/>
    <dbReference type="EnsemblBacteria" id="ADD40443">
        <property type="protein sequence ID" value="ADD40443"/>
        <property type="gene ID" value="Snas_0731"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0731"/>
    <dbReference type="eggNOG" id="COG1274">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028872_1_1_11"/>
    <dbReference type="OMA" id="GPTNNWV"/>
    <dbReference type="OrthoDB" id="267285at2"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004613">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00819">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00452">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018091">
        <property type="entry name" value="PEP_carboxykin_GTP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008209">
        <property type="entry name" value="PEP_carboxykinase_GTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035077">
        <property type="entry name" value="PEP_carboxykinase_GTP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035078">
        <property type="entry name" value="PEP_carboxykinase_GTP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11561">
        <property type="entry name" value="PTHR11561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00821">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17297">
        <property type="entry name" value="PEPCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001348">
        <property type="entry name" value="PEP_carboxykinase_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00505">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="5 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PEPCK_N" evidence="10">
        <location>
            <begin position="22"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="PEPCK_GTP" evidence="9">
        <location>
            <begin position="246"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="221"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="387"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="273"/>
            <end position="278"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="519"/>
            <end position="522"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD40443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="611" mass="67169" checksum="D2A5C3ED4C069852" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7G4</accession>
    <name>D3Q7G4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2759</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018006.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2759"/>
    <dbReference type="EnsemblBacteria" id="ADD42435">
        <property type="protein sequence ID" value="ADD42435"/>
        <property type="gene ID" value="Snas_2759"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2759"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="OMA" id="GLWRTLY"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="270"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="83"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="306" mass="33074" checksum="A61A520173D7061B" modified="2010-04-20" version="1">MTDTVPARGTLLKARKQQSRTAWTLLSPSLLFFAVFLVLPVLFAIGLAVSSWGGFDLGRIDFAGTANFAEILDPAGTFLVPILANTLLFAFGAVALALVASIAVSHAITRLRFQGLWRTLYFLPLVTTVVAVGNIWKYMYQPGSGLINGMLNAVGIPSVSFLTDPSTALPSVVVVQAWASIGTAVLILTAGLKAIPETYYEAGELDGTNAWTSFWHITLPLLRPTLLFVLITQFIAGLQSFALIIVMTQGGPANATNVAGYEMYQQAFKFGNWGVASAMALVLFVVIFVITLLQLWFFRRKGEETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7I2</accession>
    <name>D3Q7I2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019895.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4681"/>
    <dbReference type="EnsemblBacteria" id="ADD44324">
        <property type="protein sequence ID" value="ADD44324"/>
        <property type="gene ID" value="Snas_4681"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4681"/>
    <dbReference type="eggNOG" id="ENOG50316AC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098655_0_0_11"/>
    <dbReference type="OrthoDB" id="1796936at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="241" mass="26389" checksum="D5BFC78EC9772DAC" modified="2010-04-20" version="1">MWTTVAAFGRNDIRNIRRDTMLAGIVFGPFLYSVMMWLLPPITRLLDRLYGFDLVPYYPLAISGFQILGPAAVLGCIGGMLLLEDKDQRTLSALRVTPAPPLAYPLYRVLLLIAITPVFEIAALALSRRMDSESIVAAIPITVVAGATTAILATTIALLAKNKVEGLALFRAAGMLVFMVPLVPWFIDSPLGLLFGVLPPFWAAKAFWVMMDGGNHWPYTLTGAAYGAVLVILLLRRLSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7L0</accession>
    <name>D3Q7L0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Vitamin K epoxide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Snas_4709</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VKOR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019923.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4709"/>
    <dbReference type="EnsemblBacteria" id="ADD44352">
        <property type="protein sequence ID" value="ADD44352"/>
        <property type="gene ID" value="Snas_4709"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4709"/>
    <dbReference type="eggNOG" id="COG4243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082938_1_1_11"/>
    <dbReference type="OMA" id="WYWLTFN"/>
    <dbReference type="OrthoDB" id="1932901at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12922">
        <property type="entry name" value="VKOR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012932">
        <property type="entry name" value="VKOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041714">
        <property type="entry name" value="VKOR_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038354">
        <property type="entry name" value="VKOR_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07884">
        <property type="entry name" value="VKOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00756">
        <property type="entry name" value="VKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0874">Quinone</keyword>
    <keyword evidence="9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="VKc" evidence="11">
        <location>
            <begin position="20"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD44352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="208" mass="23597" checksum="FEB23EEE69A0BE43" modified="2010-04-20" version="1">MSKTDSEDRIGEDTTRPVAERTLGLILTIGGVIGLIASWALAVEKIAMLRDPDYTPSCSINPVLSCGSVMETAQAELFGFPNPFIGLMSFPVVITVGVLVLSRVRLPRWIWWGMQLGTLLGAVFITWLFIQSLYSIGALCPYCMVVWAMVMPIFWYTTVYNISRRNFSKTDGEVGDWLYLHWAGLVLWVFVLLILIMIRFWSYWQTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7N9</accession>
    <name>D3Q7N9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M43 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019952.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4739"/>
    <dbReference type="MEROPS" id="M43.008"/>
    <dbReference type="EnsemblBacteria" id="ADD44381">
        <property type="protein sequence ID" value="ADD44381"/>
        <property type="gene ID" value="Snas_4739"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4739"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048726_0_1_11"/>
    <dbReference type="OMA" id="MTMNYMD"/>
    <dbReference type="OrthoDB" id="1063831at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04275">
        <property type="entry name" value="ZnMc_pappalysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048722" description="Peptidase_M43 domain-containing protein" evidence="1">
        <location>
            <begin position="38"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M43" evidence="2">
        <location>
            <begin position="178"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="312" mass="32673" checksum="0B388515E8613D1F" modified="2010-04-20" version="1">MPTTLYTRLRRIAGVAAAVALAATTAAAPATASAVAAACDDGSALRVTKDAHGHHDPNALTGKQVAKAERELADALADRSVSQRDLAASVTVPVVFHVIMQDSTRAGGNLPDSMIAEQMKVLNDSYSGATGGADTDFQFNLVKTTRTVNASWYNVGYGSAAERDMKAALREGGADTLNIYAANIGDGLLGWATFPDRSIGSDDGVVVLNESLPGGTAAPYDGGDTATHEAGHWLNLYHTFQGGCKGKGDQVADTAAESSPAYGCPTGRDSCTRVAGVDPIHNFMDYTEDDCMYEFTAGQTTRMHEAWTAFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Q1</accession>
    <name>D3Q7Q1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4751"/>
    <dbReference type="EnsemblBacteria" id="ADD44393">
        <property type="protein sequence ID" value="ADD44393"/>
        <property type="gene ID" value="Snas_4751"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4751"/>
    <dbReference type="eggNOG" id="COG3093">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055817_1_1_11"/>
    <dbReference type="OMA" id="FHETREN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043917">
        <property type="entry name" value="DUF5753"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19054">
        <property type="entry name" value="DUF5753"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="276" mass="31153" checksum="1F92DCA558AF58D1" modified="2010-04-20" version="1">MASEAIFPRRVLGETFKRFRQAKGWSVNGAARQLGVSRDRLKNIEDGSSRLAIVDIVGICRIYGTSQAEEQELIALAEATTKYRWVEQYGQGIPQYAQKFVSMEQRATRMLIYEAEFVTGLFQTPEYLRASHARDHRYNAKSSEEIIAARLARQRALAKSDNPPQISVIFSEGVLRRMTSTPEIMTDQVERLRKANRLAYVDIAILPFDAGVHPSMSGPYIVLDFADDEPSVVYIESRDGCRYETGPDTVALYRQDFSETLPLTAPLEEIKYGTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8C5</accession>
    <name>D3Q8C5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018070.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42499">
        <property type="protein sequence ID" value="ADD42499"/>
        <property type="gene ID" value="Snas_2823"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2823"/>
    <dbReference type="HOGENOM" id="CLU_2221605_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049647" evidence="1">
        <location>
            <begin position="26"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="106" mass="11623" checksum="1C5A6FCA4D3FA931" modified="2010-04-20" version="1">MRKAIIAIATATVLTASVVGGVATAHAEGDAKGDPKGNCATKTLRLKTKKSSPVHYSPSGSSSVFGHTKRRAYTFDHYCVNKHGKRWYQFKGGRLDNGWIYTKYVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8H6</accession>
    <name>D3Q8H6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018121.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2875"/>
    <dbReference type="EnsemblBacteria" id="ADD42550">
        <property type="protein sequence ID" value="ADD42550"/>
        <property type="gene ID" value="Snas_2875"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2875"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_11"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="251" mass="25527" checksum="703CEAA4C345525A" modified="2010-04-20" version="1">MSPTRTAIVTGGAHGIGAGIARRFAADGLAVAIVDINAERAAATAESITADGGTAIALPTDIGDAQATTDAVNTAAERLGGVGVLVNNAGYARDADLPDMTTAQWDEVINIHLNAAFHTVKAAHPYMREAGWGRIINISSISALGTPGRVNYSAAKAGLLGYTKSLALELAPEGITANAIAPGFIVSDMTAATAKRLGRDFDEHQRIAADSIPVGRVGRPEDIAHAAAFFAAEAAGFITGQVVYVSGGVHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8H7</accession>
    <name>D3Q8H7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2876</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018122.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2876"/>
    <dbReference type="EnsemblBacteria" id="ADD42551">
        <property type="protein sequence ID" value="ADD42551"/>
        <property type="gene ID" value="Snas_2876"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2876"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_0_11"/>
    <dbReference type="OMA" id="PANVEGY"/>
    <dbReference type="OrthoDB" id="664909at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="342" mass="36495" checksum="34A9D429D01D3D6A" modified="2010-04-20" version="1">MASRTPAGPVTMEDVAREAGVSRAAVSKVIRDAHGVSAAMRERVTTAIATLGYRPNVSARGMRGATYTLGIEIPELANPFFPRLLAGVTAAVSASPYQLIVAPADPANVEGYRAIQALVDRQVDGVIAVSPLVEPAWLEALAATVPVVMLGRHDRASGYDTVANDDEAGTRQAMRHLIDLGHRDIAHLTCEETKTVPGSGVPQAIRLETYREVMRESGLDAHIRVVRTPTGEAGACRTATRLLTGPERPTAIFASHDEPALGVQRAIAEAGLTPMDVSVVGYDDIEIARHPGVSLTTVNQDGERIGRLAAELLLERIAGRTEPRQEIVRPELVVRSSTRPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8P2</accession>
    <name>D3Q8P2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4843</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020055.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4843"/>
    <dbReference type="EnsemblBacteria" id="ADD44484">
        <property type="protein sequence ID" value="ADD44484"/>
        <property type="gene ID" value="Snas_4843"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4843"/>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_6_11"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="199"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="405" mass="44002" checksum="DDA9BAF21806B5A0" modified="2010-04-20" version="1">MIRRWSTLPLRVRLVTLGVLGLLIGFAGGGTALVLSLHYSLRASVDDAATKTAEDIAGLLVDKKLPDRITTGRDSTIVQIYDADGKYVRGSQGADPLVPLLKEEQLAEALGDGEHFTVDVSRSQTSDPLRATAKRAGDQIVIVGVSQSELGAVSQLAVGLTITLAILAVAVTMALWWMVGWTLRPVEAARAKQRSFVADAAHELRSPLANMRTELEVAERIGAPDDLVADLLTDVERLSRMTEDLLLLARMDDARRPWRPEDLDIVKLLEVLAETYDDARVPVTTQMDRATLNLHADHDGLHRIFTNLIDNAVRHAEATVAITCTTDDSEVVVSVSDDGPGIPLEDRERVFDRFTRLDDARGRDSGGTGLGLPIVAELVAAHRGSIRLHGVIPHGLCAEVRLPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8S4</accession>
    <name>D3Q8S4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020087.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4875"/>
    <dbReference type="EnsemblBacteria" id="ADD44516">
        <property type="protein sequence ID" value="ADD44516"/>
        <property type="gene ID" value="Snas_4875"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4875"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_425723_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048950" evidence="2">
        <location>
            <begin position="25"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="638" mass="68146" checksum="B65F73A67044409F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8S7</accession>
    <name>D3Q8S7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4878"/>
    <dbReference type="EnsemblBacteria" id="ADD44519">
        <property type="protein sequence ID" value="ADD44519"/>
        <property type="gene ID" value="Snas_4878"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4878"/>
    <dbReference type="eggNOG" id="COG3688">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044346_0_0_11"/>
    <dbReference type="OMA" id="KFAGNAM"/>
    <dbReference type="OrthoDB" id="1111809at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010298">
        <property type="entry name" value="DUF901"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34547">
        <property type="entry name" value="PTHR34547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05991">
        <property type="entry name" value="NYN_YacP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="190"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="357"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="507" mass="55094" checksum="D82C2185718EC5CD" modified="2010-04-20" version="1">MLPRFVVPRTGSVMNAPAGGRRDTGDFREPQPPPPPGPPVPPDPPGPPEPPPGPLPPPPPPGPPEPTDPPSVDDEPELPEAVWQKLLPLASTALGSIRPDELPGPLRRFARFAPARRAKLAEPGLRSALRTDASFRQQVAEVARKTQSSLMDLIDAGEVPEGADTLDVAALAYVSRGTNWRDLLGSASRRVAERLEAERISARIAEAEQAAASAAHDKAIAEREAEKLRVELVEARAEAEELRRRHHGLTKELREIKRRERKVTDALSSEKGRLKQAETEHAAELRRLKSQLDESMRALERARQGARDTRALNDARVWQLLETIGGAAAGLRRELALEPAEHTPGDFVADTEAVRPGSAEPTERPRGLDSDDPARLDTLLGMPQSHLIVDGYNVTLGGYGDIPLEQQRIRLVRGLSGIAAQTGAEVTVVFDGSHHMVGLPTPPRGVRVLFSRKGQTADEVIRALTRAEPNGRPVIVISSDREVADGVRRHGAYPLSAKTLLRRLNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8T6</accession>
    <name>D3Q8T6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Extracellular solute-binding protein family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4887</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4887"/>
    <dbReference type="EnsemblBacteria" id="ADD44528">
        <property type="protein sequence ID" value="ADD44528"/>
        <property type="gene ID" value="Snas_4887"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4887"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_18_4_11"/>
    <dbReference type="OMA" id="APFFNGV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049796" evidence="2">
        <location>
            <begin position="42"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="74"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="315" mass="34797" checksum="86C7D7866DD1C598" modified="2010-04-20" version="1">MTRIVEVRDPRAVKGTPVRLMRRAVLAVAVLSVAVATGCQADTVDDTVPPFYNIDQAERSEMPKEVRDILDSGRLTIGSKFDQPLTGLRDKATGRIEGFDAEIGRIITQRIFGKVAEGENLDFIETVPANREKYLEDGTVDLVLATYTITPERKKAVTFAGPYYEAGQAIMTRKGEGIEDIKDLSKKKVCAAEGTTSLDNVEKHNPRANVSKPMRNWSSCRQALLEKEYDAVSTDDVILYGFLSEDPSKLEISKKTFTTEPYGIGLPKGSTELQKFINETLELAFDNGDWQTAFDSTLAVAEVPDPESPPNITEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8U5</accession>
    <name>D3Q8U5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Glutamine synthetase</fullName>
            <ecNumber evidence="7">6.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_4896</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16169"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 6">Oligomer of 12 subunits arranged in the form of two hexagons.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4896"/>
    <dbReference type="EnsemblBacteria" id="ADD44537">
        <property type="protein sequence ID" value="ADD44537"/>
        <property type="gene ID" value="Snas_4896"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4896"/>
    <dbReference type="eggNOG" id="COG0174">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017290_1_2_11"/>
    <dbReference type="OMA" id="PHPHEFE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004809">
        <property type="entry name" value="Gln_synth_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001637">
        <property type="entry name" value="Gln_synth_I_adenylation_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027302">
        <property type="entry name" value="Gln_synth_N_conserv_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00653">
        <property type="entry name" value="GlnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00180">
        <property type="entry name" value="GLNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00182">
        <property type="entry name" value="GLNA_ADENYLATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="8">
        <location>
            <begin position="109"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-AMP-tyrosine" evidence="4">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR604809-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="479" mass="53628" checksum="CF7A80895710C53C" modified="2010-04-20" version="1">MRNPAVFTSPDQLLAYIKDNKVKFIDVRFCDLPGVMQHFNVPAESFTEETFAEGLAFDGSSIRGFQAIHESDMLLLPDVTTAFLDPFRAEKTVALNFFIHDPFTREAYSRDPRNIAKKAEQYLASSGIADTAYFGAEAEFYIFDDVRFDTAPQHGFFHIDSVEGAWNSGKVEEGGNRGYKPKHKGGYFPVPPVDHFADLRDGIVRTLVDTGIEVERAHHEVGTAGQTEINYKFSTLLNAGDQLQLFKYIVKNQVWAAGKTATFMPKPMYGDNGSGMHTHQSLFRDGTPLFYDETGYAGLSDTARWYIGGLLKHAPSLLAFTNPTVNSYRRLVPGYEAPVNLVYSQRNRSACTRIPVTGNNPKAKRVEFRVPDPSSNPYLAFSSMLMAGLDGIKNKIEPPDPVDKDLYELAPEEFGDVAQVPGSLPEVLDKLESDHGFLLEGGVFTPDLIETWIDYKRTAEVDEIRLRPTPQEFLLYFDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8W0</accession>
    <name>D3Q8W0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Virulence factor Mce family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0858</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016140.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0858"/>
    <dbReference type="EnsemblBacteria" id="ADD40569">
        <property type="protein sequence ID" value="ADD40569"/>
        <property type="gene ID" value="Snas_0858"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0858"/>
    <dbReference type="eggNOG" id="COG1463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040159_2_0_11"/>
    <dbReference type="OMA" id="VGHGPWC"/>
    <dbReference type="OrthoDB" id="336531at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005693">
        <property type="entry name" value="Mce"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024516">
        <property type="entry name" value="Mce_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11887">
        <property type="entry name" value="Mce4_CUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00996">
        <property type="entry name" value="Mtu_fam_mce"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049798" evidence="2">
        <location>
            <begin position="40"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="3">
        <location>
            <begin position="32"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Mce4_CUP1" evidence="4">
        <location>
            <begin position="117"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="452" mass="48729" checksum="A18F4E28E20C9CD0" modified="2010-04-20" version="1">MKQRIAGLGFLLVLAALLGLCVASYMKLFSPKVDVTVQAATAGLQMSRGADVKLHGVLVGEVRDINSTGDGAELDVALDPDSTASIPAGVTARLLPKTLFGEKYVELIAPKSDTGGSIQPNTVVKEDKSKEAVELNDVLDGALPLLRAVPPEKLSVTLSAIAGALDGRGDELGDTIVKLGDIVRTLNKEMPTIEADIDELAKVLDNYRGALPDLTKVLENLTVTNKTITDQEDELQAMWMSTQDFSDDTRVFLDRYQGRLIQFGEVTQPFIELLATYSPEYPCLFQGLTELQPDIEEAFSGGRLHITLEITQNNGKYESGRDEPEWTSQYGPNCRGLPEGNSEAAENQFGNGYDYDGERSNLPIEIPGLTDAPAQEDDEGTNAENKDDEDEDGPGVELPFDPMMGYAGTEEEQSVFTPMVAASTGSDVTDLNGDLVSLLYGPIFRGATISAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Z3</accession>
    <name>D3Q8Z3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP-N-acetylglucosamine pyrophosphorylase related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016173.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0891"/>
    <dbReference type="EnsemblBacteria" id="ADD40602">
        <property type="protein sequence ID" value="ADD40602"/>
        <property type="gene ID" value="Snas_0891"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0891"/>
    <dbReference type="eggNOG" id="COG1213">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_5_0_11"/>
    <dbReference type="OMA" id="GGVLWMN"/>
    <dbReference type="OrthoDB" id="1557977at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="1">
        <location>
            <begin position="6"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="230" mass="25054" checksum="9D4E11310BB9A271" modified="2010-04-20" version="1">MATNIVILAAGVGSRLGRPHPKPLTPLSDGETILHRALRHLTSRFSRHSIHLVVGFKKEMIMEAAPDVGFIYNQDYGDTNTSKSLLKALTITGPGGVLWLNGDVVFDEAVLDDLLPHIAMDRSFVCVNTESVAEEEVKYTLDSDGYIAELSKVVASGALGEAVGINFISSGDRALLARRLDECDAQDYFERGLELAIAKDGMKVEALDISRHPVIEVDFAEDLARANETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q910</accession>
    <name>D3Q910_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0908</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016190.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0908"/>
    <dbReference type="EnsemblBacteria" id="ADD40619">
        <property type="protein sequence ID" value="ADD40619"/>
        <property type="gene ID" value="Snas_0908"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0908"/>
    <dbReference type="eggNOG" id="COG5555">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044344_0_0_11"/>
    <dbReference type="OrthoDB" id="1303819at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01839">
        <property type="entry name" value="FG-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049804" evidence="3">
        <location>
            <begin position="30"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="482" mass="49727" checksum="DA46AB45B4620CEF" modified="2010-04-20" version="1">MRRETIRLWSGVAAAAVVAASALAITAYAQAGDFNRELTFDLDCDDKRDAVEGVPYATVEGHEAAGAVKVKYSKTGEKATISQATPGVPGSPEPEDDFGTAVTSYDENGDGCDDLVVSSHQEDVIGKDGKNHQNAGMIWVIPGSPSGLDTQAARGIHYETPGIPGSLGVNQYFGERLLASNSTDGPYLLIVAPGLDDANGAVYFLRAAKAYKITQDSPGVSGAAEPEDNFGATLAVNDRYFAIGSPGEEIDGADGAGMAHVFSLQAVNGTMKQLGAVHQNTSGISGVAEKNDGFGGGLSVVPYQPSSGAKAIPLLSVGAPGEDIGGVQAGQDAGMAHLITFPSTGTYKQVVAAHENTPGVPGEAEGGDNFGYSSVLVPTEPSGVATPLTAHWVVAGGIYDGDGENHYTALYVLRVSESPGGGNAKVIDGDDYGLWFDEANAGCSLQADTKFLYCGYPPAAGVPWGNILHGESEPTEFYRVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9I3</accession>
    <name>D3Q9I3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018236.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2991"/>
    <dbReference type="EnsemblBacteria" id="ADD42665">
        <property type="protein sequence ID" value="ADD42665"/>
        <property type="gene ID" value="Snas_2991"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2991"/>
    <dbReference type="eggNOG" id="COG2220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070266_1_0_11"/>
    <dbReference type="OMA" id="THFDHAM"/>
    <dbReference type="OrthoDB" id="767622at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="13"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="275" mass="30481" checksum="18B8991738A73631" modified="2010-04-20" version="1">MTSKAEITVSWLGTNAWEVISGGKTILVDPWVSRFPTEGKDGKFNPNTPLSVDEKAVDEHINGADTVLITHSHYDHMGDVPYIAKQTEATVLGTETHLNLLRAMDTPEEQLAQVGGGELYQFDGYTIEVFASTHSVAGKHKTQLFGGTLTEVPKRPTKVKHLLEGGSLSYLVTFGKTSLFFVATPGFHEREIAGIRPTVLFMQGTTPNYPRYEKRMFEATGYPPYVIPTHWDDFAAPLKEPAIDEYGAAKLREKVAEVSPSSKFIQLDHLESHTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9I7</accession>
    <name>D3Q9I7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Shikimate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018240.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2995"/>
    <dbReference type="EnsemblBacteria" id="ADD42669">
        <property type="protein sequence ID" value="ADD42669"/>
        <property type="gene ID" value="Snas_2995"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2995"/>
    <dbReference type="eggNOG" id="COG0703">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057607_4_3_11"/>
    <dbReference type="OMA" id="KIMARSH"/>
    <dbReference type="OrthoDB" id="1392851at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="153" mass="16771" checksum="2B7C82C2C5A320AA" modified="2010-04-20" version="1">MGTGKTTTGRLVAEALGLPMTDSDAYLNERYGHSANQIAETLGPDVLHAREAEHVLDALERTPRVIAAAASVVEDPRVREALRTPFVVWLDAPDAVLEQRMQSSSHRPDFDPETLRARREPHYRELADLTVDVAANRPEPAARLILDAVGASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9K5</accession>
    <name>D3Q9K5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3016</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3016"/>
    <dbReference type="EnsemblBacteria" id="ADD42687">
        <property type="protein sequence ID" value="ADD42687"/>
        <property type="gene ID" value="Snas_3016"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3016"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_12_2_11"/>
    <dbReference type="OMA" id="MNFAWAG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041490">
        <property type="entry name" value="KstR2_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17932">
        <property type="entry name" value="TetR_C_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="209" mass="23433" checksum="3EC2CA21AA28522D" modified="2010-04-20" version="1">MTPVKPKRVPRAIREQQMLDASVEVFARRGYHPAGVEEIAEIAGISKPMVYLYFGSKEELFVACIRREANRLMEMITQLVDPQDPPKEQLWSALRGFFSFVSDHSGAWIVLYRQARTQGGPSAREVDEMRRRTVELIAAMLSQAAGMRKPGEQAVTAAHALVGSCESLADWMLDTPGTSAETTAKRLMHFAWPGLEELMEATRAKRAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9M2</accession>
    <name>D3Q9M2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020139.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4927"/>
    <dbReference type="EnsemblBacteria" id="ADD44568">
        <property type="protein sequence ID" value="ADD44568"/>
        <property type="gene ID" value="Snas_4927"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4927"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105064_0_0_11"/>
    <dbReference type="OMA" id="PTAIAWC"/>
    <dbReference type="OrthoDB" id="2049098at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="66"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="23224" checksum="67B186216210F623" modified="2010-04-20" version="1">MRPDPDAHTRELAAKATTDPTGWFEELYAEAADGRATVPWDRGVPAALLAEWARDLDGTGKRAMVVGCGLGRDSEFIASLGFDTVAFDVSATAIATTKARHPDSRVDYVTADLLDLPGDWRHAFDLVVEDMTVQSLPDPPRAQAIANIPPLVGPGGTLLVVAAANLTGAATDGPPWPLVRAEIDAFATDGLRAANVECVPDATDPAINRWRAEFRRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA42</accession>
    <name>D3QA42_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1044</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016325.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1044"/>
    <dbReference type="EnsemblBacteria" id="ADD40754">
        <property type="protein sequence ID" value="ADD40754"/>
        <property type="gene ID" value="Snas_1044"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1044"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_11"/>
    <dbReference type="OMA" id="VTEWLGN"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03301">
        <property type="entry name" value="ABC_MalK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015855">
        <property type="entry name" value="ABC_transpr_MalK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040582">
        <property type="entry name" value="OB_MalK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17912">
        <property type="entry name" value="OB_MalK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="387" mass="42252" checksum="40EA676BF5C18B64" modified="2010-04-20" version="1">MAEIVLDKIAKRYRGGTDVIRELSLTIADEEFLILVGPSGCGKSTVLNMIAGLEDITSGELRIGGERMNERAPQDRNIAMVFQSYALYPHMSVRENIAFPLAIAKLPKNQIAEKVDKAAEMLELGGFLDRRPGELSGGQRQRVAMGRAIVRSPQAFLMDEPLSNLDAKLRAQMRTSISRLQKSLATTTVYVTHDQTEAMTLGDRIVVLRDGIAQQIGSPADLYERPSNLFVAGFIGSPTMNFLPGSISDGKVATAIGQLPLTDAARSDLSDNNAGRDVIVGLRPEAFEDDSYTGGEGRFHFDDTVDIVESLGSSKLVYFNLERPADSPELVEIAKLMGAKDRFGSAQVVCQIDARSTAREGQNLRVSFDPRDTLLFDPHNGRRIGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAF8</accession>
    <name>D3QAF8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Abhydrolase_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3070"/>
    <dbReference type="EnsemblBacteria" id="ADD42741">
        <property type="protein sequence ID" value="ADD42741"/>
        <property type="gene ID" value="Snas_3070"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3070"/>
    <dbReference type="HOGENOM" id="CLU_2791965_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_4" evidence="2">
        <location>
            <begin position="2"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="68" mass="7361" checksum="A2FEF16A45E8D0A6" modified="2010-04-20" version="1">MRHDYATPHRSSKDVADRNDAPLLTYDGFGHIAYRSGRDCVSKALDAFLIDKTPVPDGTVCPGATTVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAI6</accession>
    <name>D3QAI6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sporulation and cell division protein SsgA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3098</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell septum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SsgA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018340.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3098"/>
    <dbReference type="EnsemblBacteria" id="ADD42769">
        <property type="protein sequence ID" value="ADD42769"/>
        <property type="gene ID" value="Snas_3098"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3098"/>
    <dbReference type="eggNOG" id="ENOG5032RFA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126599_0_1_11"/>
    <dbReference type="OMA" id="NDEPVEW"/>
    <dbReference type="OrthoDB" id="1627707at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.31.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006776">
        <property type="entry name" value="SsgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038658">
        <property type="entry name" value="SsgB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04686">
        <property type="entry name" value="SsgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0749">Sporulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="15663" checksum="4F556E7CE409DEC6" modified="2010-04-20" version="1">MATTRPATVEVDTTMRFVATDFTTVNVRASMRYDADDPYAIHVMFHPGNPDAEQVSWSFARELLAAGLVEPTGMGDVRVWPWSTPRGDAIALALSSPDGNALFEVSRSLVSRFLRRSYALVPKGKEGDSLDMDATVAKLLADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAL3</accession>
    <name>D3QAL3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate kinase FGGY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3125</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FGGY kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3125"/>
    <dbReference type="EnsemblBacteria" id="ADD42796">
        <property type="protein sequence ID" value="ADD42796"/>
        <property type="gene ID" value="Snas_3125"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3125"/>
    <dbReference type="eggNOG" id="COG1070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009281_3_3_11"/>
    <dbReference type="OMA" id="AAYQKKW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="2">
        <location>
            <begin position="8"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="3">
        <location>
            <begin position="261"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="498" mass="53001" checksum="41DB06A58F6F3DB9" modified="2010-04-20" version="1">MTGDNAILLGVDIGTSSSKAVAVDRRGSILARAERAHETATPHPGWFEHDAETVWWDDFRYLVGRLLEHVDGRDIAGLATSGIGPVLLPADGDGRPLRPAILYGVDTRASAEIDELDAEFGAEAIMERGGTPLSSQAVGPKIRWLAKHEPDVWRRTEKLLMASSYLVHRLTGEYVLDHHSASQCDPLYDQRSFGWARDWAEKVAPGLALPRLAWPGEVVGAVSATAAAATGLPRDLPVMAGTVDAWAESVSVGVREPGETMVMYGTTMFIVNVAADPRPHRGLWTTSGAMPGTFSLAAGMATSGSVTDWLRRLVGGDFAELTAAAATVPAGSRGLLLLPYFAGERTPIFDPEARGVIAGLTLAHGPAELYRAALEGIAHGVRHNLETMASAHGSIERLVAVGGGTKGGLWTQIVSDVTNQAQDIPSHTIGACLGDAMLAAHGLGLDVDLAAWNPVTATVRPDPARAEAYDAFYRHYRELYPATSDVAHFLAHQQKLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAR4</accession>
    <name>D3QAR4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020281.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5074"/>
    <dbReference type="EnsemblBacteria" id="ADD44710">
        <property type="protein sequence ID" value="ADD44710"/>
        <property type="gene ID" value="Snas_5074"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5074"/>
    <dbReference type="eggNOG" id="ENOG5033ZYV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1164800_0_0_11"/>
    <dbReference type="OMA" id="TPATEPW"/>
    <dbReference type="OrthoDB" id="2231578at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="238" mass="23921" checksum="4041B3ADB546C7FB" modified="2010-04-20" version="1">MNENSRDETTPPDSPPGSLGTALRSITATRSRRWLSAITLLIGLIIPILLSVTLPASDQTFASIASPTQALMSVTVPCVGVLLAAELRRATAPVRLIPTLAAAVAAAAAVGAYGSATSAIAVVATPATEPWGDAAIVAASGPLLQSSAMLVGTGLGLLLRPSLVACLATVVLPLGAWALLGLPADGAAQPWLTPFGAAQNLLAGLPIGLAQWLAVAVLWSGGLNLLGAIRLRGVGPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAY9</accession>
    <name>D3QAY9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5150"/>
    <dbReference type="EnsemblBacteria" id="ADD44785">
        <property type="protein sequence ID" value="ADD44785"/>
        <property type="gene ID" value="Snas_5150"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5150"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_0_2_11"/>
    <dbReference type="OMA" id="MGYGIFL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048384" evidence="1">
        <location>
            <begin position="32"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="53"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="369" mass="40658" checksum="8A976B69A546EF23" modified="2010-04-20" version="1">MNTRTRLSRRGLVATTVGAASALAVGGGAWAWATSGHETIDEYLRDNLPDDASLAIVAVRGGKTLYRKGFGLADRKADIRCGHRTVFDIGSVTKQFTGAAILRLDMDGALKVSDPLSRHLPGLPADKRKITLHQLLTHTGGFTDLPDLSDYDEVDRSRLLSEFGDRELKWKPGTRYEYSNLGYSVLAAVIEIVTSGNYEEYLADNLFHPAGMRHTGYLLPDWDPATVAQQYDDKGRVMGKPHELPWDDDGPYWILRGNGGILSTARDMTAWHRALDGDEVLSAKAKRKLFKPHVPEDETGESHYGYGWTISTDEAGRKVVWHDGGNEWSSAMIVRCPEAETMLFLASNAADWGGDMQTLAVDILPLLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBD8</accession>
    <name>D3QBD8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bifunctional protein PyrR</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="4">Pyrimidine operon regulatory protein</fullName>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="4">Uracil phosphoribosyltransferase</fullName>
                <shortName evidence="4">UPRTase</shortName>
                <ecNumber evidence="4">2.4.2.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="4" type="primary">pyrR</name>
        <name evidence="6" type="ordered locus">Snas_3149</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil</text>
            <dbReference type="Rhea" id="RHEA:13017"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018391.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3149"/>
    <dbReference type="EnsemblBacteria" id="ADD42820">
        <property type="protein sequence ID" value="ADD42820"/>
        <property type="gene ID" value="Snas_3149"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3149"/>
    <dbReference type="eggNOG" id="COG2065">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094234_2_1_11"/>
    <dbReference type="OMA" id="PIQPDFC"/>
    <dbReference type="OrthoDB" id="1725260at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01219">
        <property type="entry name" value="PyrR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023050">
        <property type="entry name" value="PyrR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="18"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="PRPP-binding" evidence="4">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="186" mass="20412" checksum="EDCA272914AD580B" modified="2010-04-20" version="1">MAQRARDPGKRPLLSSADIARIIDRIAHQILEKTGGDDNTVLLGIPTRGVPLARRLAERIKTFEGLDVPHGSLDVTLYRDDLRMRGARALGPTDIPASGVDDKRVILVDDVLYSGRTVRAALNGLYDLGRPAWVQLAVLVDRGHRRLPIRADYVGKNLPTAIADSVSVLVSEMDGEDAVYVDREEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBE7</accession>
    <name>D3QBE7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA-directed RNA polymerase subunit omega</fullName>
            <shortName evidence="11">RNAP omega subunit</shortName>
            <ecNumber evidence="2 11">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">RNA polymerase omega subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10 11">Transcriptase subunit omega</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rpoZ</name>
        <name evidence="13" type="ordered locus">Snas_3158</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the RNA polymerase subunit omega family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 11"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018400.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3158"/>
    <dbReference type="EnsemblBacteria" id="ADD42829">
        <property type="protein sequence ID" value="ADD42829"/>
        <property type="gene ID" value="Snas_3158"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3158"/>
    <dbReference type="eggNOG" id="COG1758">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125406_1_1_11"/>
    <dbReference type="OMA" id="QHADSKY"/>
    <dbReference type="OrthoDB" id="1864134at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00366">
        <property type="entry name" value="RNApol_bact_RpoZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003716">
        <property type="entry name" value="DNA-dir_RNA_pol_omega"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006110">
        <property type="entry name" value="Pol_omega/Rpo6/RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036161">
        <property type="entry name" value="RPB6/omega-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34476">
        <property type="entry name" value="PTHR34476"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01192">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01409">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63562">
        <property type="entry name" value="SSF63562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00690">
        <property type="entry name" value="rpoZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD42829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="106" mass="11508" checksum="3A3B72933BDE15D9" modified="2010-04-20" version="1">MSGTVADPTGITKPPIDDLLEKTHSKYQLVIYGAKRARQINAYYSQLGEGLLEYVGPLVETTPQEKSLSIALREIDQDLLITEALPDVEDTPKGPSGVPAVETDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBG9</accession>
    <name>D3QBG9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3181"/>
    <dbReference type="EnsemblBacteria" id="ADD42851">
        <property type="protein sequence ID" value="ADD42851"/>
        <property type="gene ID" value="Snas_3181"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3181"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089258_3_0_11"/>
    <dbReference type="OMA" id="TDENRWF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="6"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="177" mass="20179" checksum="8631F8CA970A6DEE" modified="2010-04-20" version="1">MLKLAILGFLRDHPLHGYDLKSRIAALTGHVKPIADGTLYPAIKRLETAGMLTRRSAPGKVAAPRHMLELTQKGIDHLTWLLRDPEDLTISDENRWFTLLAFLRHLDNPREQAIVLRRRLAFLSEPVPYFFDEHGRPAAVDDFDDPFRQGLLSIAHAKTNTEFAWLNATIAELDRHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBQ6</accession>
    <name>D3QBQ6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_3268</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018509.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3268"/>
    <dbReference type="EnsemblBacteria" id="ADD42938">
        <property type="protein sequence ID" value="ADD42938"/>
        <property type="gene ID" value="Snas_3268"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3268"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_9_11"/>
    <dbReference type="OMA" id="SNISMVF"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="17"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="329"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="361"/>
            <end position="368"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD42938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="581" mass="61765" checksum="963B25759A76F16D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBT6</accession>
    <name>D3QBT6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcriptional regulator WhiB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">whiB</name>
        <name evidence="14" type="ordered locus">Snas_5190</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">The Fe-S cluster can be nitrosylated by nitric oxide (NO).</text>
    </comment>
    <comment type="PTM">
        <text evidence="11">Upon Fe-S cluster removal intramolecular disulfide bonds are formed.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the WhiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020396.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5190"/>
    <dbReference type="EnsemblBacteria" id="ADD44825">
        <property type="protein sequence ID" value="ADD44825"/>
        <property type="gene ID" value="Snas_5190"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5190"/>
    <dbReference type="eggNOG" id="ENOG5034BAK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106245_1_0_11"/>
    <dbReference type="OMA" id="RPHEVAI"/>
    <dbReference type="OrthoDB" id="1798393at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035731">
        <property type="term" value="F:dinitrosyl-iron complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01479">
        <property type="entry name" value="WhiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034768">
        <property type="entry name" value="4FE4S_WBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003482">
        <property type="entry name" value="Whib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38839">
        <property type="entry name" value="PTHR38839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02467">
        <property type="entry name" value="Whib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51674">
        <property type="entry name" value="4FE4S_WBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="4Fe-4S Wbl-type" evidence="13">
        <location>
            <begin position="40"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD44825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="111" mass="12284" checksum="DC28620B35AE41BA" modified="2010-04-20" version="1">MSHTKKAPKPEEIEAARHDPRLRRAHETRRSDPEWRMRGRCVAVDPETFFPDPQVKQSPRAALAVCSACAVQSTCLAWALDAGDCNGVWGGTTPGERKAMVVAWRDFVPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBX7</accession>
    <name>D3QBX7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5232"/>
    <dbReference type="EnsemblBacteria" id="ADD44866">
        <property type="protein sequence ID" value="ADD44866"/>
        <property type="gene ID" value="Snas_5232"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5232"/>
    <dbReference type="HOGENOM" id="CLU_131550_0_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="2">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="DUF397" evidence="2">
        <location>
            <begin position="24"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="79" mass="8631" checksum="C86B1AADB14DCB1B" modified="2010-04-20" version="1">MTGPWRKSSRSGAGNSSQCVETRANWRKSTRSGQGSSSQCLETRAHGPHVDVRDSKTPELGFLSMSASDWDAFLTTVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC20</accession>
    <name>D3QC20_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase class-II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020480.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5275"/>
    <dbReference type="EnsemblBacteria" id="ADD44909">
        <property type="protein sequence ID" value="ADD44909"/>
        <property type="gene ID" value="Snas_5275"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5275"/>
    <dbReference type="eggNOG" id="COG0121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042555_2_0_11"/>
    <dbReference type="OMA" id="DVRNTHP"/>
    <dbReference type="OrthoDB" id="693464at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026869">
        <property type="entry name" value="EgtC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13230">
        <property type="entry name" value="GATase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="288" mass="31606" checksum="FD0288028535C8C8" modified="2010-04-20" version="1">MCRLFGLTTGGPRVETAFWLLDAPDSLRAQSLRMPDGAGIGWFSLGDEPVRDRAPLAAHTSSDFDLLARNIVSHTFVAHVRYSSGTALDVHNTHPFDMNDRLFAHNGVVRDMDVLSTWLSDVDKALIEGHTDSELVFAYITAEIRRLGDTTEGLISAVRRIGAELPIYSLNILLAEANRLWALRYPETHELWVLRPELGGFAGTRALAPVAEPGRMEISGTDGAVPAFVLASERMDADPDWRLMEPGELLVIDGLDATSLFPFDKPTTVLTRADLSGNELRSQEPATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTZ7</accession>
    <name>D3PTZ7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015326.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0033"/>
    <dbReference type="EnsemblBacteria" id="ADD39755">
        <property type="protein sequence ID" value="ADD39755"/>
        <property type="gene ID" value="Snas_0033"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0033"/>
    <dbReference type="HOGENOM" id="CLU_521670_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="522" mass="54092" checksum="A300E10057965FAA" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU85</accession>
    <name>D3PU85_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1322"/>
    <dbReference type="EnsemblBacteria" id="ADD41031">
        <property type="protein sequence ID" value="ADD41031"/>
        <property type="gene ID" value="Snas_1322"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1322"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087580_2_1_11"/>
    <dbReference type="OMA" id="RAMAHPV"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="210" mass="23622" checksum="4C4524DD6863299D" modified="2010-04-20" version="1">MSLCKRMFARMNDPEELETVHLDATNLRGVAHPVRVKMLGMLRSDGPATATSLAQRLGMNTGATSYHLRQLAEYGFVVEDPERGVGRERWWKAAHYSSNYSSEDHRVEPEDAETYVRAVAQTTAEQVLRSVDERATLPQEWRAAGTLSSYMLKLTPAELRELNEQVEAVIRSFRAALPEPVDAPEGSARVTVQYQAFPHTADLDFETDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU99</accession>
    <name>D3PU99_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016616.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1337"/>
    <dbReference type="EnsemblBacteria" id="ADD41045">
        <property type="protein sequence ID" value="ADD41045"/>
        <property type="gene ID" value="Snas_1337"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1337"/>
    <dbReference type="eggNOG" id="COG0412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112481_1_0_11"/>
    <dbReference type="OMA" id="PGDQHLF"/>
    <dbReference type="OrthoDB" id="1889569at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DLH" evidence="1">
        <location>
            <begin position="4"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="189" mass="20042" checksum="4A978E0FD536B18C" modified="2010-04-20" version="1">MTEVVLFHHSQGLTTGVRALAAELRSAGHTVHTPDLFDGRIFDSIEAGVGYANETGFRQRGVDFAAGLPAGVVYAGFSLGVMPAQQLAQTRAGAKGALLFEACVPASEFGGWPKGLPVQIHGMDADEFFAGEGDVDAARELVEGNAEAELFLYPGDKHLFADETLLSFDAEATSLLTRRVIAFLDALDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV46</accession>
    <name>D3PV46_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction protein with Nacht domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1392"/>
    <dbReference type="EnsemblBacteria" id="ADD41099">
        <property type="protein sequence ID" value="ADD41099"/>
        <property type="gene ID" value="Snas_1392"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1392"/>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009117_0_0_11"/>
    <dbReference type="OMA" id="HRTVQEY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="283"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1091" mass="121371" checksum="FEE83C5E3013579E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV98</accession>
    <name>D3PV98_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016722.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1445"/>
    <dbReference type="EnsemblBacteria" id="ADD41151">
        <property type="protein sequence ID" value="ADD41151"/>
        <property type="gene ID" value="Snas_1445"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1445"/>
    <dbReference type="HOGENOM" id="CLU_2366692_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="102" mass="11525" checksum="FB3CF8DA0686351D" modified="2010-04-20" version="1">MKQLLIRVDDEVHARLRQRAKDEGRSVNALLNELVLIASQVDRESARDRIRSRAAAMGMLSVIPPAPLSPPLSLKQYRQAIDGARGWGQIIDDILDEDRERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVJ4</accession>
    <name>D3PVJ4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydrogenase expression/formation protein HypD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3444</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HypD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018679.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3444"/>
    <dbReference type="EnsemblBacteria" id="ADD43108">
        <property type="protein sequence ID" value="ADD43108"/>
        <property type="gene ID" value="Snas_3444"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3444"/>
    <dbReference type="eggNOG" id="COG0409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048562_1_0_11"/>
    <dbReference type="OMA" id="MRYLDEY"/>
    <dbReference type="OrthoDB" id="666873at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11740">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002780">
        <property type="entry name" value="Hyd_form_HypD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042243">
        <property type="entry name" value="HypD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042244">
        <property type="entry name" value="HypD_2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30149">
        <property type="entry name" value="PTHR30149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01924">
        <property type="entry name" value="HypD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005622">
        <property type="entry name" value="Hydrgn_mat_hypD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00075">
        <property type="entry name" value="hypD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="369" mass="39918" checksum="79428B6BEE60F1B9" modified="2010-04-20" version="1">MKYLDEYRDPVLARRLLSELESTATRPWTLMEVCGGQTHTIVRQGIDELLPHGIRMIHGPGCPVCVTPLEMVDKAIAIASRDGVIFCSYGDMLRVPGSGGDLLGVKARGGDVRVVYTPLDAVSLAVANPDRQVVFFAVGFETTAPANAMAVKQAASLGLDNFSVLVSHVLVPPAITAILDAPDNEVTAFLAAGHVCAVMGWTQYEPIAAAYRVPIVVTGFEPLDLIEGIVMAVRQLETGRAEVENQYVRAVRRTGNSRARDTIDEVFTLTDRTWRGIGEIAHSGLRLSEAYRHHDAETRFPVEREATRESEVCIAGEILRGTRLPTDCLAYGTACTPRHPLGAPMVSAEGTCAAFHTAGRGRQATLEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW83</accession>
    <name>D3PW83_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1537</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016811.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1537"/>
    <dbReference type="EnsemblBacteria" id="ADD41240">
        <property type="protein sequence ID" value="ADD41240"/>
        <property type="gene ID" value="Snas_1537"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1537"/>
    <dbReference type="eggNOG" id="COG0545">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013615_12_0_11"/>
    <dbReference type="OMA" id="RVIAGWD"/>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061077">
        <property type="term" value="P:chaperone-mediated protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044609">
        <property type="entry name" value="FKBP2/11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779">
        <property type="entry name" value="PTHR45779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="35"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="124" mass="13483" checksum="5B771FA20C586882" modified="2010-04-20" version="1">MALERPIIEKEDRHPPQYLEIDDIVVGEGAEARKGADIDVHYVGVSLSTGQEFDASWNRGQAFTIPLGAGRVIPGWDQGLVGMKVGGRRKLTIPPHLAYGNQSPTPAIKPGETLVFVVDLIDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWC2</accession>
    <name>D3PWC2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016850.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1576"/>
    <dbReference type="EnsemblBacteria" id="ADD41279">
        <property type="protein sequence ID" value="ADD41279"/>
        <property type="gene ID" value="Snas_1576"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1576"/>
    <dbReference type="eggNOG" id="COG0412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054590_7_3_11"/>
    <dbReference type="OMA" id="CDERESY"/>
    <dbReference type="OrthoDB" id="1889569at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DLH" evidence="1">
        <location>
            <begin position="22"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="247" mass="26743" checksum="C3768DF32C3A2573" modified="2010-04-20" version="1">MTGPTEAVATVGERVNVGTSGMGAYVARPDRPGTYPGVLIGFEIFGVTPYIRRMADRVASLGYLAIAPDFHHRDAPGVELTADAEGRSRGLELTRRLTRASVAEDLDATREYLERRPEATGAEAMVGFSLGGHIGFVAAAHLKLKALAAFYPGWLTGGDIPLSTPEPTLELTDDISGRVLLVLGEGDHLIDAEQRDRIAARFAGTRHDLVVYPWAPHGFACDERESYDADYTRHAWSLVAKVLAEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWE8</accession>
    <name>D3PWE8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">3-hydroxyacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.1.35</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1602</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.35" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016876.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1602"/>
    <dbReference type="EnsemblBacteria" id="ADD41305">
        <property type="protein sequence ID" value="ADD41305"/>
        <property type="gene ID" value="Snas_1602"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1602"/>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_2_0_11"/>
    <dbReference type="OMA" id="CEVIVES"/>
    <dbReference type="OrthoDB" id="862072at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="5">
        <location>
            <begin position="3"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="4">
        <location>
            <begin position="184"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="4">
        <location>
            <begin position="301"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2 3">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="1">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="342" mass="36160" checksum="221D19493C044BAE" modified="2010-04-20" version="1">METVGVIGLGTMGAGIAEVFAKAGLHVIGVDIDDAAVERGRGHLAKSLDRQVAKGRLDADTRTAIDTRLTLTTDFEGLATTRLVVEAVPELLDIKRATFTRLDQHCGADTILATNTSSLSIAEIAGFTSRPAKVIGMHFFNPAPIMKLVEVVRGADTDPEVVAYVEELSRRLGKTPVTVADRPGFVVNRLLVGYLNQAAKLLDSQSAGRDEVDAAIKAAGLPMGPFMLMDVVGLDTLVEILDVIHADSGSPRHEAAGSLRSLVADGKLGRKSGAGFYDHSQSVAEAEVAADRVAELQRELILPHIGEAQEMADSGYASESDIDTAMKLGCGYPDGVFGLLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWQ4</accession>
    <name>D3PWQ4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43276">
        <property type="protein sequence ID" value="ADD43276"/>
        <property type="gene ID" value="Snas_3616"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3616"/>
    <dbReference type="eggNOG" id="ENOG503326I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1738150_0_0_11"/>
    <dbReference type="OMA" id="CLVWHLA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045590">
        <property type="entry name" value="DUF6463"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20064">
        <property type="entry name" value="DUF6463"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="144" mass="15658" checksum="32C156D5BFB48171" modified="2010-04-20" version="1">MNRTRTLAHVAGWIAVVVGVIHTLAALWDRLSTWADILSRGPWETISLDVTTDNRVYSEAFWYSPGSFGIPLLLFGGLVLWTVRRGARVPAPLGWGMTAWGAVMSALLPASPAWALLLAGVLLILAAHTSRRHGATEHAKPVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWT0</accession>
    <name>D3PWT0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018873.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3644"/>
    <dbReference type="EnsemblBacteria" id="ADD43302">
        <property type="protein sequence ID" value="ADD43302"/>
        <property type="gene ID" value="Snas_3644"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3644"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="VAFGRVH"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="36008" checksum="B1C98F9C5BF1B40A" modified="2010-04-20" version="1">METDTAQLRAFVTIASTGHIGRAAERLRLTQQGVSKRLAQLERRLGLRLADRHSGGVRLTAAGQRLLPHARTIVAAWDVAVEELHGDRRLTLVVDGLYEPLAPQLWLRGAAADPRFTVRSAPRDIPASQVEAVLGGYVDVAFGRANTTPWPRELSRAVALLEPLALLTGPGHHLARRPRVRTQELSDLELWFPGGGSPAQWRQLAAEFESTFDVGIRDSRATVSFAHFLETAENDASACTIIGLAMEPPPPPLRAIPIVDPVPVFPWAAIWPSRIPRATVDLLLEHVDARHLVPVDQAADRERVWMPEADREWITARATQPSPGPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX60</accession>
    <name>D3PX60_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Formyl-CoA transferase</fullName>
            <ecNumber evidence="1">2.8.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.8.3.16" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1620"/>
    <dbReference type="EnsemblBacteria" id="ADD41323">
        <property type="protein sequence ID" value="ADD41323"/>
        <property type="gene ID" value="Snas_1620"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1620"/>
    <dbReference type="eggNOG" id="COG1804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033975_2_0_11"/>
    <dbReference type="OMA" id="HRPGFGT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033608">
        <property type="term" value="F:formyl-CoA transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="SSF89796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="404" mass="43087" checksum="E1782BCF780447E8" modified="2010-04-20" version="1">MMHLIRCIVVEALSGIKVVDISTLFAGPTAAMLLGDFGADVVKVEHPRRGDPSRGHGHAKDGVGLWWKVLSRNKRTVAIDLSSEDGQGVLRALLAEADVLVENFRPGTLERWNLAPESLLEANPRLVISRVTGFGQIGPMAGEPGFGTLAEAMSGFASMTGEPDGPPTLPPLALADGIAALACAYAIMVALRARENTGRGQVVDLAIIEPILTVLGPQITAFQALGVIPQRTGNRSSNNSPRNTYRSRDGRWLAVSTSAQSIAERVMHLVGRPELVDEPWFSSGRTRAEHAEELDAAVGGWIAERDAEEVIAAFSEAQAAIAPVYDVSDVVDDPQFRALGTVLEVPDEELGSVAMQNVMFRMSDTPGEVRWAGPRLGEHTDEVLAEAGLDAEQIAALRDKGVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX91</accession>
    <name>D3PX91_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1652</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016925.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1652"/>
    <dbReference type="EnsemblBacteria" id="ADD41354">
        <property type="protein sequence ID" value="ADD41354"/>
        <property type="gene ID" value="Snas_1652"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1652"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_2_11"/>
    <dbReference type="OMA" id="WRVHVRT"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="22"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="196" mass="21191" checksum="9CC5D27D3B9B0F84" modified="2010-04-20" version="1">MRQRPELQVGAENPPRERADAARNRAKILAAAAELFAAADARGITMDEIAKAAGVGRGTLYRRYPDVASIAVALLDEHESRLQGELISGPPPLGPGAEPVERLAAFYAAMVELLERHGHLVLGAETGAARFATGAYGFWRAHVMSLAREAEVDDPEALTDTLLAPLAPDVYRHQRDQGLSVERIRTALRQLAGLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXA9</accession>
    <name>D3PXA9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF418 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016943.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41372">
        <property type="protein sequence ID" value="ADD41372"/>
        <property type="gene ID" value="Snas_1670"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1670"/>
    <dbReference type="eggNOG" id="COG2311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039610_1_0_11"/>
    <dbReference type="OMA" id="VEWIWRC"/>
    <dbReference type="OrthoDB" id="1742337at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04235">
        <property type="entry name" value="DUF418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="DUF418" evidence="2">
        <location>
            <begin position="233"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="405" mass="43574" checksum="4D1D0A254F28BF18" modified="2010-04-20" version="1">MSQTLPPPAAHAARGPVRARERALAPDLARGFMLLFIALANAGGVVFAATEPAIEPTPHGFESVVNFGMMMFVSGHAYPMFAVMFGYGLVQMSRRQREAGASTAAARDTLVRRNAWLIAFGAVHAVLLYFGDFLAAYGLVGIIAACLLLNRGDKFHRVIVWLWGLVLVEAAVFMALVYPSLSTDFGATPKPARVDSLAATSYGESLVDRLAEWPLHTASVLGFIFIVWLGMWAARRRVLEEPARHRPLLIGATVVGLGVGFLGSLPQALVSAGALSTDNADLTLLLHNLGGMYSGPGYVAAFGLIALWLTKNRAAPTDTLITGSLVALGRRSLSGYLFQSVSWFVLLLPFTFAMPQWFGNKTLLYLLVATATWLATVVTAAALQRRGHPGPAEALLRRLAYGPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXF4</accession>
    <name>D3PXF4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016988.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1718"/>
    <dbReference type="EnsemblBacteria" id="ADD41417">
        <property type="protein sequence ID" value="ADD41417"/>
        <property type="gene ID" value="Snas_1718"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1718"/>
    <dbReference type="HOGENOM" id="CLU_983209_0_0_11"/>
    <dbReference type="OrthoDB" id="871480at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="283" mass="30495" checksum="63EE9E0062D9B549" modified="2010-04-20" version="1">MPPQPSEVDSDDTATEPQWHDYVEQSLLPHWRRQAEAAYRAIRRVTRAEEATLDSLLRAIGAEGGEAVRSRLERAHFPDGGYDALILTAALDSGAVRITADWDSATVLETPDGTGFDPGVLAGALAKADRASVPDVLGGLTKAGIDLERASGGTTVADADTARAKGALANMKLDGRPHDLVVTDEGLLFLGCPKATDDGEKRLRLLLTAADGVKGLASRPDARWLPFEEFSRVRILKHSPIRAMVTLHDGTEHDFGWSWAGEQIGASDNLLDEVLSDMAQRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXL4</accession>
    <name>D3PXL4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SCP-like extracellular</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3687</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3687"/>
    <dbReference type="EnsemblBacteria" id="ADD43344">
        <property type="protein sequence ID" value="ADD43344"/>
        <property type="gene ID" value="Snas_3687"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3687"/>
    <dbReference type="eggNOG" id="COG2340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048111_3_0_11"/>
    <dbReference type="OMA" id="NGKIWWT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="SSF55797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048449" evidence="2">
        <location>
            <begin position="31"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="47"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="167" mass="18363" checksum="BFE36584B3DA4441" modified="2010-04-20" version="1">MTPKKRKLALVATAAATVTIAAAIPFTVFAEAPLPPEHGEFVKEVVDLTNEHRKDHGCGKLTMDTELSVPAQEHSQDMADNDFMSHTGSDGRDPGQRVSDSDYPGQYRAENVAAGYTTPEKVVDGWMNSEGHRANILNCELEDIGVGYAENEDSEYRSYWTQNFGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXL8</accession>
    <name>D3PXL8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Roadblock/LC7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018919.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3691"/>
    <dbReference type="EnsemblBacteria" id="ADD43348">
        <property type="protein sequence ID" value="ADD43348"/>
        <property type="gene ID" value="Snas_3691"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3691"/>
    <dbReference type="eggNOG" id="COG2018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094585_0_1_11"/>
    <dbReference type="OMA" id="DMGQAAF"/>
    <dbReference type="OrthoDB" id="1635683at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Robl_LC7" evidence="1">
        <location>
            <begin position="7"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="131" mass="13592" checksum="0B5DD544D5626E46" modified="2010-04-20" version="1">MRSDEVVFLLNDFTDRVYEVTHVLAVSADGLLVACNDGLSEAEADRLAAIASGLVSLLNGAARTLNAFPVGSNLTELNGGYMFSLSVSSGASLLALASYDCDIGQVGHELATLINKVGPALSPDKRGRHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXM0</accession>
    <name>D3PXM0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3693</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3693"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43350">
        <property type="protein sequence ID" value="ADD43350"/>
        <property type="gene ID" value="Snas_3693"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3693"/>
    <dbReference type="HOGENOM" id="CLU_1659672_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048678" evidence="1">
        <location>
            <begin position="31"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="33"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="159" mass="17033" checksum="5051D0760C10AEE5" modified="2010-04-20" version="1">MPRLKAALVVALATALGLIGAVSVSGSAQAATRSPMVIKNMQTDRCLSSNSAGTVHSNPCSGSDNQIWDRTLDGDSNSTLRNRATGRYLQAHANETVTTQPRSGSAAQKWRISHSPHEGYWRIKNLGNGKCLSNYGSSDPRTTRTLTCGPSTFDAWKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXQ1</accession>
    <name>D3PXQ1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3724</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018952.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3724"/>
    <dbReference type="EnsemblBacteria" id="ADD43381">
        <property type="protein sequence ID" value="ADD43381"/>
        <property type="gene ID" value="Snas_3724"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3724"/>
    <dbReference type="eggNOG" id="ENOG50338NK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131457_2_0_11"/>
    <dbReference type="OMA" id="LYDYFRA"/>
    <dbReference type="OrthoDB" id="1759329at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="164" mass="17627" checksum="9356A300CFB7DD3F" modified="2010-04-20" version="1">MGVLTDYFRAADAADVVRAMRTEDGDPLVNGEHAVFEGVEAKGVDAPIVLGALIAAIRQVPWSADLVAETMVWPTTPMPGPDGPAAEDDPWATGPWVSRLDPAVRDTLADALDAALPDTVARWARTEELYGASAEDLLPVAQSLVTLARRARDDDQQLYCWVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY29</accession>
    <name>D3PY29_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Activator of Hsp90 ATPase 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5728"/>
    <dbReference type="EnsemblBacteria" id="ADD45358">
        <property type="protein sequence ID" value="ADD45358"/>
        <property type="gene ID" value="Snas_5728"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5728"/>
    <dbReference type="eggNOG" id="COG3832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108923_6_1_11"/>
    <dbReference type="OMA" id="FYGMESW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="169" mass="18868" checksum="8ED6D9CB6397796F" modified="2010-04-20" version="1">MNTPLPGLGLRVVASGATDLVLTRVFDAPSALVFDAMTKPELLRRWHGARGWWLTECEVDLRRGGAWRFVSRGPNGATMEMYGTFREVAPPHRLVQTEIHRDWDEGAALVTTVLDETDGRTTMTVTARYSSTEIRDQVVRSPMERGAGEAYERLAAVLADALIRERDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY43</accession>
    <name>D3PY43_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020943.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5742"/>
    <dbReference type="EnsemblBacteria" id="ADD45372">
        <property type="protein sequence ID" value="ADD45372"/>
        <property type="gene ID" value="Snas_5742"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5742"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063440_3_2_11"/>
    <dbReference type="OMA" id="WNTDESR"/>
    <dbReference type="OrthoDB" id="1706427at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="24"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="112" mass="12656" checksum="58DD2EB930C3403D" modified="2010-04-20" version="1">MDTEELILSQAQELRRGTVVLACLALLKQPQYGYALLETLNDAGIPVDGNTLYPLLRRLEKQGLLASEWNTDESRPRKFYKTSPEGLAVCTGLVREWQSLVTSMSELTKEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY60</accession>
    <name>D3PY60_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zf-CGNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020960.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5759"/>
    <dbReference type="EnsemblBacteria" id="ADD45389">
        <property type="protein sequence ID" value="ADD45389"/>
        <property type="gene ID" value="Snas_5759"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5759"/>
    <dbReference type="eggNOG" id="COG5516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087298_1_1_11"/>
    <dbReference type="OMA" id="PCRNAYL"/>
    <dbReference type="OrthoDB" id="1478254at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010852">
        <property type="entry name" value="ABATE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023286">
        <property type="entry name" value="ABATE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021005">
        <property type="entry name" value="Znf_CGNR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35525">
        <property type="entry name" value="PTHR35525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07336">
        <property type="entry name" value="ABATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11706">
        <property type="entry name" value="zf-CGNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160904">
        <property type="entry name" value="SSF160904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-CGNR" evidence="1">
        <location>
            <begin position="127"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="178" mass="19643" checksum="EE2341117C53B7AA" modified="2010-04-20" version="1">MDFDAYAQTAADLVNAELTDMASLHDFFGGRVWWTERATERDLSTLRRAKRKLREVFVKGSSGDDAGAVEILNTLLQQFPVQPRISGHSDQDWHMHVTSRGSAVASEFVAGAVWGLSSWLCRYKGARFGVCADARCGNVYLDTSSNNCRRFCSERCATRSHVAAHRARKREAAAAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYB3</accession>
    <name>D3PYB3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017051.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1783"/>
    <dbReference type="EnsemblBacteria" id="ADD41480">
        <property type="protein sequence ID" value="ADD41480"/>
        <property type="gene ID" value="Snas_1783"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1783"/>
    <dbReference type="eggNOG" id="COG3564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134343_0_0_11"/>
    <dbReference type="OMA" id="GSAPMCF"/>
    <dbReference type="OrthoDB" id="1912908at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008497">
        <property type="entry name" value="DUF779"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05610">
        <property type="entry name" value="DUF779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009151">
        <property type="entry name" value="DUF779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="125" mass="13867" checksum="7360C964918B9E14" modified="2010-04-20" version="1">MTLRQVDLTEAAARLLRELTVRHGRLMFHQSGGCCDGSSPMCYPLGELNLGDADHHLGDLDVPGLDEPVPVWMTVAQYQYWSHTHLTIDVVPGRGAGFSLEAPEGVRFLIRSRLLTEDELAQLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYE5</accession>
    <name>D3PYE5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017083.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1816"/>
    <dbReference type="EnsemblBacteria" id="ADD41512">
        <property type="protein sequence ID" value="ADD41512"/>
        <property type="gene ID" value="Snas_1816"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1816"/>
    <dbReference type="HOGENOM" id="CLU_2669285_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="75" mass="8548" checksum="7A7315F303FD920C" modified="2010-04-20" version="1">MSSEWIWGIWLLIAALSFGGLEAWAILSKNREPKTLTEVLRRWLGVEPKRWWRGIASAGLLAGVSWVVLHLLFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYH7</accession>
    <name>D3PYH7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017115.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1848"/>
    <dbReference type="EnsemblBacteria" id="ADD41544">
        <property type="protein sequence ID" value="ADD41544"/>
        <property type="gene ID" value="Snas_1848"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1848"/>
    <dbReference type="eggNOG" id="ENOG5033ZG5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1029084_0_0_11"/>
    <dbReference type="OMA" id="GTEPPFW"/>
    <dbReference type="OrthoDB" id="2047341at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="285" mass="31045" checksum="F31617813E52953F" modified="2010-04-20" version="1">MTGSPVLPLRPLTIGELLDAAAAVLRSRWRSLLGMAFALALVEQIGMTTLRLLTVDEVKPKYTDQIVDNELLAWLWIMLGLTTELICISLLSGPATRVAVAAVRDEDPATLPPTVLDSRQWGPVLLFSMIIGVAGLVAAVLCVLPWFMVFALFGLSIPALVADGLPPDKAFWRSPKLFKRSSGRTAGVRLMAYFTWLIIRLVITCGAVVLLESGLIDFTTVLFDYFLVFLGVCYLAVNTAGYAMLACVDAVLHIETRVRTEGLDVVVSRMRARGQPVDISAPEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ07</accession>
    <name>D3PZ07_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5806</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45436">
        <property type="protein sequence ID" value="ADD45436"/>
        <property type="gene ID" value="Snas_5806"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5806"/>
    <dbReference type="eggNOG" id="ENOG5032CN4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_741682_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048105" evidence="2">
        <location>
            <begin position="44"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="373" mass="40217" checksum="F9978E5C11231C72" modified="2010-04-20" version="1">MPHIFVPMPSSTLRRVAAPLVAAALLATAASCASIGGTLTAPAEHTVITKAKDLRPDKPYLSEDGDKPGMLIGPHYKLAVSGYTATTEVPEDNARVYGFDQPMAVPDDSEFFLAIMDGKSQVHSNEKVKAELTVNDKKRPLDRLPGPSEAIAAVIPAKADVKLTVTDEEKSQTINLRDGKRSEQIDGYYNGGLESDDPVDYDSKGKITADAGAQYEKEKRTLNISMKVGAATKAPWIESKGWADKGKVWVSVPISDMTTDSVYGFAPGSHEPGVDWTLKERELFSLNPNEGKATDSKGKESFKADQSSQTTDGTSSLFSPSEVTLLFQVSDKTTKAELKISPRGKMKAVWANVTGSCSWNDKPSAKEISLAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ35</accession>
    <name>D3PZ35_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5834</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5834"/>
    <dbReference type="EnsemblBacteria" id="ADD45464">
        <property type="protein sequence ID" value="ADD45464"/>
        <property type="gene ID" value="Snas_5834"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5834"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_0_11"/>
    <dbReference type="OMA" id="ERWEHAP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="18"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="236" mass="25932" checksum="CC724AD35AD8DB00" modified="2010-04-20" version="1">MNRMTARTRRAPRQAEAERNDRALVEAAKAVVAVDGAHASVAAIAARAGVGIGSLYRRYRTKEELFQHLLSVTLDQYLEAAEAGLAIEDPWEGFAHYVRTILEIGPGWMGPIAGTIGLTEEINEKNRRADELVAAVVERAHTAGVLRDDATLVDVELLIEQLGKSPLLDQLETKGRVELMDAARDARARITEIVLDGLRAKDNPRLPGRAPGYELFSARWERAEADLVTAHPDPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ51</accession>
    <name>D3PZ51_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021051.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5851"/>
    <dbReference type="EnsemblBacteria" id="ADD45480">
        <property type="protein sequence ID" value="ADD45480"/>
        <property type="gene ID" value="Snas_5851"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5851"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_11_2_11"/>
    <dbReference type="OMA" id="VQVWHVY"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="425" mass="45797" checksum="43F0A173C59817C7" modified="2010-04-20" version="1">MRRQLAETFRSLRVRNYRLFAIGQLTSLLGRWMQIVAIDWLVLELSGNSGAALGFVTALQFVPVLLLSLHGGKLADRHDKRRMLLVFNTSWLALSAGMAVIVLIGAAQLWHIYVFALMLGMVMALENPARQSFVSEMVGTGMLPNALSLSAATFNSARIVGPAIAGALIAVVDTGPVLAITALTYVPPMVCLLLMNRHELGFSEPAKDTRIREAVSYTFRRSDLVLPLVLMFVVGGLGFNFPITLALLSKTVFHTGAATFGLLTTMLAVGALAGALVSSRRRARPTAHIVLAAAAIFGVLEALVGFAPAFWVAAVLLVPTGFSMTFLAQAVNQRIQLGVDAAHRGRVMALYILVFLGSTPIFAPIIGWLSEVIGPRSGLWIGGLAGVFMAATAFAVRCRKRDVHVSVELRPRPRMRLIETVEKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ58</accession>
    <name>D3PZ58_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,4-dihydroxy-6-naphtoate synthase</fullName>
            <ecNumber evidence="3">4.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Menaquinone biosynthetic enzyme MqnD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mqnD</name>
        <name evidence="4" type="ordered locus">Snas_5858</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MqnA/MqnD family. MqnD subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021058.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5858"/>
    <dbReference type="EnsemblBacteria" id="ADD45487">
        <property type="protein sequence ID" value="ADD45487"/>
        <property type="gene ID" value="Snas_5858"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5858"/>
    <dbReference type="eggNOG" id="COG2107">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070326_0_0_11"/>
    <dbReference type="OMA" id="RGCGPLV"/>
    <dbReference type="OrthoDB" id="1107067at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00996">
        <property type="entry name" value="MqnD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003773">
        <property type="entry name" value="Menaquinone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030869">
        <property type="entry name" value="MqnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37167">
        <property type="entry name" value="PTHR37167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02621">
        <property type="entry name" value="VitK2_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="52"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="106"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="264" mass="28270" checksum="2E808E0BCEBB8B5F" modified="2010-04-20" version="1">MKLAFSPCPNDTFIFHAWVHGLVEGAPVPEVTYADVDVTNTRALTGEFDVVKVSFAALPWLRDGYELLPCGGALGRGCGPLVLTRQPSSPEKLAGATVAVPGERTTAYLLFRLWSQGFAPANIRVVPFAEIMPGVASGRFDAGLVIHEARFTYQDHGLSMLEDLGDWWERETGHPIPLGAILARKGLDTDAIAGWIRASLAHAWANPLDSAAYVAEHAQELSADVTRQHIELYVNEFSADLGEAGRAAVETLLGRAASAGLVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ66</accession>
    <name>D3PZ66_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mucin-associated surface protein (MASP)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5866</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021066.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5866"/>
    <dbReference type="EnsemblBacteria" id="ADD45495">
        <property type="protein sequence ID" value="ADD45495"/>
        <property type="gene ID" value="Snas_5866"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5866"/>
    <dbReference type="eggNOG" id="ENOG5030J68">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116311_2_1_11"/>
    <dbReference type="OMA" id="GICALSM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048485" evidence="2">
        <location>
            <begin position="20"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="135" mass="13788" checksum="EFB4407C0CAEBB42" modified="2010-04-20" version="1">MIVRAVRAVRAVRAVRAVRAVRGCSQGGFATAELAAAFPAIILLLLTGLFAVSAVATQTRCADAAREAALAAARGEDGSEAATRHLPPTAQLAIDATGDTVSAKVTAEIRPLGSLLPTMTVIGRATAAREDREAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZB3</accession>
    <name>D3PZB3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1524 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017158.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1891"/>
    <dbReference type="EnsemblBacteria" id="ADD41587">
        <property type="protein sequence ID" value="ADD41587"/>
        <property type="gene ID" value="Snas_1891"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1891"/>
    <dbReference type="eggNOG" id="COG2356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043034_3_1_11"/>
    <dbReference type="OMA" id="RTAYRCT"/>
    <dbReference type="OrthoDB" id="1510738at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011089">
        <property type="entry name" value="DUF1524"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07510">
        <property type="entry name" value="DUF1524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048721" description="DUF1524 domain-containing protein" evidence="1">
        <location>
            <begin position="36"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1524" evidence="2">
        <location>
            <begin position="115"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="219" mass="23804" checksum="67A29A2CAC91147B" modified="2010-04-20" version="1">MPGTARLPRRILIGFMVSVFVFAALAIAWPSPAAAIPANIPSKSVIQSELNGLSVASEGSMTGYSRDKFPHWVTISGSCNARETILKRDADYVTVGSDCYPTSGKWYSQWDGVVKTVASEVSIDHQVPLAEAWRSGASSWTTAKRQDFANDVVGTELIAVTATVNSSKGDKDPSAWKPPRTGAYCLYAKMWIHAKHKWGLKLQSAEKTALQSMLNTCSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZH4</accession>
    <name>D3PZH4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MMPL domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_1952</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017219.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1952"/>
    <dbReference type="EnsemblBacteria" id="ADD41648">
        <property type="protein sequence ID" value="ADD41648"/>
        <property type="gene ID" value="Snas_1952"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1952"/>
    <dbReference type="eggNOG" id="COG2409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005108_5_2_11"/>
    <dbReference type="OMA" id="IPAMRVY"/>
    <dbReference type="OrthoDB" id="149255at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="530"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="556"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="598"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="639"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="675"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="MMPL" evidence="8">
        <location>
            <begin position="95"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="MMPL" evidence="8">
        <location>
            <begin position="406"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="706"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD41648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="729" mass="78145" checksum="D51458FB64CCF041" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZT4</accession>
    <name>D3PZT4_STANL</name>
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        <submittedName>
            <fullName evidence="2">Peptidoglycan-binding domain 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3969</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
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                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="Snas_3969"/>
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    </dbReference>
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        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ADD43621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="232" mass="25046" checksum="8B36C90B1D948E3C" modified="2010-04-20" version="1">MTIPGARIMKGCHMAWRLARSLENLRREINQIAPHRSKVSDGTIGDGAHQSGPSDHNPNSSGVVCAFDATHDPDSGADMRKIAEHLRTKRHRAIKYVIFNRRIASAASGWRWTGYFGKNPHTQHMHVSVGRGPDGRSTGPYDDPGPWGLGTTRGDDVIGLRKGDSGERVKGLQAVLERAGFKVTVDGDYGPKTAAALLACRKSMGSTADDGNSVTGYAYAQLLTALARKQDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZY2</accession>
    <name>D3PZY2_STANL</name>
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        <submittedName>
            <fullName evidence="2">Transcriptional regulator, SARP family</fullName>
        </submittedName>
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        <name evidence="2" type="ordered locus">Snas_4017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
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            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="Snas_4017"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4017"/>
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    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="96"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="535" mass="58584" checksum="CB325B8AE658C6B2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZZ7</accession>
    <name>D3PZZ7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5898</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
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            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021097.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5898"/>
    <dbReference type="EnsemblBacteria" id="ADD45526">
        <property type="protein sequence ID" value="ADD45526"/>
        <property type="gene ID" value="Snas_5898"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5898"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033626_0_0_11"/>
    <dbReference type="OMA" id="GGEMAHY"/>
    <dbReference type="OrthoDB" id="867226at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="7"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="408" mass="44302" checksum="8E64C5C213592E4E" modified="2010-04-20" version="1">MSHNETATVCVVGGGPAGAMLSLLLARAGIKVTLLEKHEDFLRDFRGDTVHPSTLAVLDQLGLSERFHALPHRKISGIDLLKDGSRSEVANFGRLKVRHPYIAMIPQWDFLDFLTGEAARYPNFTLRMNTRFTDVLTAEGRVRGVTYRGPDGEGSIRAGLVVAADGRHSDAREALGLRARQRGVAIDVVLFRISRRDDDPDERITVRVGGGDILGLIDRGDYWQAFVEIPKGTGIRELRAAGIEAFREQVTRLAPFLADRVGEIASMDSLNFLDVQATRLPRWHVPGALVIGDAAHCMSPVGGVGINLAIQDAVATANLLTEPLLRAQRHGTAPPTRALAAVRRRRALPASVIQVLQDAAIRYDPATIADRGRTSRAGSSLAQRLLGRVIGMGLRPESVRNGRILAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q018</accession>
    <name>D3Q018_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5919"/>
    <dbReference type="EnsemblBacteria" id="ADD45547">
        <property type="protein sequence ID" value="ADD45547"/>
        <property type="gene ID" value="Snas_5919"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5919"/>
    <dbReference type="eggNOG" id="ENOG5032SMG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124443_1_0_11"/>
    <dbReference type="OMA" id="PTDERCP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035169">
        <property type="entry name" value="DUF5318"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17249">
        <property type="entry name" value="DUF5318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="154" mass="17288" checksum="AF83AA8EFB671642" modified="2010-04-20" version="1">MHLTTADVDYSLQRRRLLRDVQSGRVDVAEVCDASPYLVSASKFHGEETSQRCPICRREYLWLVHYIFGDELRSSAGQARGRAELAMLARSVRHFDVYVVEVCRGCGWNHLINRFALGRDNPTPEPAASVTSPASPGEVGHTSRDMSRPIRTDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0E6</accession>
    <name>D3Q0E6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Aspartate 1-decarboxylase</fullName>
            <ecNumber evidence="9">4.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Aspartate alpha-decarboxylase</fullName>
        </alternativeName>
        <component>
            <recommendedName>
                <fullName evidence="9">Aspartate 1-decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="9">Aspartate 1-decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="9" type="primary">panD</name>
        <name evidence="11" type="ordered locus">Snas_0089</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H(+) + L-aspartate = beta-alanine + CO2</text>
            <dbReference type="Rhea" id="RHEA:19497"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="EC" id="4.1.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="9">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; (R)-pantothenate biosynthesis; beta-alanine from L-aspartate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterooctamer of four alpha and four beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="9">Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PanD family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.11" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015381.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0089"/>
    <dbReference type="EnsemblBacteria" id="ADD39810">
        <property type="protein sequence ID" value="ADD39810"/>
        <property type="gene ID" value="Snas_0089"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0089"/>
    <dbReference type="eggNOG" id="COG0853">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115305_0_0_11"/>
    <dbReference type="OMA" id="MLYSKIH"/>
    <dbReference type="OrthoDB" id="1751990at2"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00002"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004068">
        <property type="term" value="F:aspartate 1-decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006523">
        <property type="term" value="P:alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06919">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00446">
        <property type="entry name" value="PanD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003190">
        <property type="entry name" value="Asp_decarbox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21012">
        <property type="entry name" value="PTHR21012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02261">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00223">
        <property type="entry name" value="panD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 9" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0704">Schiff base</keyword>
    <keyword evidence="5 9" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5023491603" description="Aspartate 1-decarboxylase beta chain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023491602" description="Aspartate 1-decarboxylase alpha chain" evidence="9">
        <location>
            <begin position="25"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="73"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid" evidence="9">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser)" evidence="9">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD39810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="150" mass="15679" checksum="E8CCD54AE8421C08" modified="2010-04-20" version="1">MLRTMLKSKIHRATVTEADLHYVGSCTVDEDLLEAADILPGEQVSIVDITNGSRLETYVIPGERGTGVLGINGAAAHLVHPGDLVILISYAAMDDREAREFEPKIVHVDSGNRIVALGNDATAAAPGTAGDPVTSPNVARNSVRGTAPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0H2</accession>
    <name>D3Q0H2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017279.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2013"/>
    <dbReference type="EnsemblBacteria" id="ADD41708">
        <property type="protein sequence ID" value="ADD41708"/>
        <property type="gene ID" value="Snas_2013"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2013"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_10_2_11"/>
    <dbReference type="OMA" id="AAFQYWV"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049420" evidence="1">
        <location>
            <begin position="25"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="423" mass="45697" checksum="9F18AC95382D430B" modified="2010-04-20" version="1">MRAKIATLAALVMLAATGCGLSGEDSGGDVDVSGEVTGKVSLQTWALKPKHTKYVEKLIDGFEDKYPGTKVKWLDQPGDGYSEKVLNQAANDELPDVVNLPPEFALPLADKELLLDVADTDDKLKKDYLSGAIDAYRFPGVKGAYGYPWYLNTDVNYWNADLMKKYGLDPDKPPTSFEDLVAQAKTMKKKSDGKMFLMSRKPSWEDLTNAGVEILSSDGEKFTFNTDAAAELLDGYRDAYADGLLPDDVLTDAYLGNSELFKQKKVAWSTGGGNFINDVKVDNPKLAKDIVPSKALDTPPLYVQGLSVSKKSDNLPTAVALARWVTNADNQADFAERVPGIFPSTTASADDESFSESDGSGAGDAKKLAFESLAEAELLKPVVVDDAINDVFNQQISLAVSGETSSKQALDKAAEECTKLLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0J3</accession>
    <name>D3Q0J3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phenylacetate-coenzyme A ligase</fullName>
            <ecNumber evidence="1">6.2.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phenylacetyl-CoA ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2034</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-phenylacetate + ATP + CoA = AMP + diphosphate + phenylacetyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:20956"/>
            <dbReference type="ChEBI" id="CHEBI:18401"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57390"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.30"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Aromatic compound metabolism; phenylacetate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the phenylacetyl-CoA ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.30" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017300.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2034"/>
    <dbReference type="EnsemblBacteria" id="ADD41729">
        <property type="protein sequence ID" value="ADD41729"/>
        <property type="gene ID" value="Snas_2034"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2034"/>
    <dbReference type="eggNOG" id="COG1541">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035301_1_1_11"/>
    <dbReference type="OMA" id="GVAPHFQ"/>
    <dbReference type="OrthoDB" id="839891at2"/>
    <dbReference type="UniPathway" id="UPA00930"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047475">
        <property type="term" value="F:phenylacetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05913">
        <property type="entry name" value="PaaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028154">
        <property type="entry name" value="AMP-dep_Lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011880">
        <property type="entry name" value="PA_CoA_ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14535">
        <property type="entry name" value="AMP-binding_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006444">
        <property type="entry name" value="PaaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02155">
        <property type="entry name" value="PA_CoA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="101"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C_2" evidence="3">
        <location>
            <begin position="344"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="437" mass="47978" checksum="81F7D2F631D50332" modified="2010-04-20" version="1">MTTRRLGDGPPKDLLDPAERMSLDELRATQLTRLRASLRHAYDNVEGYRRAWDAAGVAPQDLRSLDDLALFPFTTKEDLRSGYPFGRFAVPMERVRRVHASSGTTGQPTVVGYTEADLSMWADVMARSIRAAGGRPGHKVHVAYGYGLFTGGLGAHAGAERAGCVVIPVSSGMTARQVRLICDFQPEIIMVTPSYMLTIVDEFERQGIDPASTSLRVGVFGAEPWTEAMRTEIEARLDIHAVDIYGLSEVIGPGVAQECVESKDGLHVWEDHFYPEIVDPETGAVLPEGAEGELVFTSLTKEALPIVRYRTRDLTRLLPGTARPAFRRMEKITGRSDDMLIVRGVNVFPTQIEEILLRTEHVAPHFQLRLSLAGRLDQLEVIAEARTGTDAAQREAAEDAIAAAVKENIGIAVTARLAEPGTLERSVGKARRVLDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0L5</accession>
    <name>D3Q0L5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017322.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2057"/>
    <dbReference type="EnsemblBacteria" id="ADD41751">
        <property type="protein sequence ID" value="ADD41751"/>
        <property type="gene ID" value="Snas_2057"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2057"/>
    <dbReference type="eggNOG" id="ENOG5032A5T">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1675865_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="194" mass="20366" checksum="64010BC14D6C3399" modified="2010-04-20" version="1">MTSHPQSPAPMPGQQSPVQAMSPRSPAGPTSTVPVPPRGPGVVVPFAAPPRDPDKSRLAVGIVVGVVAFVLVCGGAVAGAVGVLVWSSNELAAQSTQTAERFLDDIVEEDYQGAYKSLCSSTRKQISVEEFTKDWSSLGVVNAETVGANTSQQQDLVVVAELTVEDGSMQDIELTVALEQQNMKMAVCGWDTVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0T0</accession>
    <name>D3Q0T0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4028"/>
    <dbReference type="EnsemblBacteria" id="ADD43680">
        <property type="protein sequence ID" value="ADD43680"/>
        <property type="gene ID" value="Snas_4028"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4028"/>
    <dbReference type="eggNOG" id="COG1985">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036590_7_2_11"/>
    <dbReference type="OMA" id="VRANMIA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="26"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="242" mass="26267" checksum="2A57AC068AFABD82" modified="2010-04-20" version="1">MARYSELSSLDQSELTDWYAPSAPDWLRVNFVSSADGAVEVNGDSKALSGEDDMRVFRILRMRCDVLVVGAGTVRTDGYRALRLSQDRVEWRRAAGLPDHPVMAVVSRSGILDLDTPLFREAPVRPIVITPEDLDAKRLAELSDVADVVAAGTGSVDFAEAFERLRQRGLRQILCEGGPHVFGEITAAGLVDELCLTLSPHLAGAGSGRITAGPPSPLKRMHLAHCLHANGNLLLRYTRVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0T2</accession>
    <name>D3Q0T2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Nuclease SbcCD subunit D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sbcD</name>
        <name evidence="10" type="ordered locus">Snas_4030</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'-&gt;5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 7">Heterodimer of SbcC and SbcD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the SbcD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019253.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4030"/>
    <dbReference type="EnsemblBacteria" id="ADD43682">
        <property type="protein sequence ID" value="ADD43682"/>
        <property type="gene ID" value="Snas_4030"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4030"/>
    <dbReference type="eggNOG" id="COG0420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038045_3_1_11"/>
    <dbReference type="OMA" id="GNHDQHS"/>
    <dbReference type="OrthoDB" id="1831911at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004593">
        <property type="entry name" value="SbcD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026843">
        <property type="entry name" value="SbcD_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12320">
        <property type="entry name" value="SbcD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00619">
        <property type="entry name" value="sbcd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="8">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="SbcD_C" evidence="9">
        <location>
            <begin position="277"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="387" mass="41773" checksum="01BD8A66802DF1B6" modified="2010-04-20" version="1">MRILHTSDWHIGATLKGQSRMAEQIAVFGELVELAKTERPDLIIVAGDLFETAAPSAAAQKLLVRTLSALRGTGAEVIAVAGNHDHGAAIDALRGWADAAGITLRGTVGKAADHLIRGETRDGEAWRCAALPFVSQRYAVRATELFDLTSAETGQSYADHLRRLVAALSAGFSDDAVNLVTGHLTVVGGKVGGGEREAHTVADYAVPATIFPPTVHYAALGHLHRHQRINGGCPIRYSGAPIAVDFGEESYTPGVVLVDVTATTPATARHVPLTSARSLKTLRGTLEELREATMDDEAWIRVYVKEHPRAGLREEVQELFPNALAVHIDPTMTREGETPRVRRAGRSPRQLFGDYLDERGHEDPAVAELFDRLYDQVSTVPVPTEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0U3</accession>
    <name>D3Q0U3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019264.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4041"/>
    <dbReference type="EnsemblBacteria" id="ADD43693">
        <property type="protein sequence ID" value="ADD43693"/>
        <property type="gene ID" value="Snas_4041"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4041"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_5_0_11"/>
    <dbReference type="OMA" id="DAPNIPQ"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="148" mass="16037" checksum="7483433AB92C747E" modified="2010-04-20" version="1">MTQEEQDLLSGAALTSFRLSGQFLAVAEKLARPVGLTAAWWQVLGAVLREPLPVAGIARAMGITRQSVQRIADRLVNDGLAEYLPNPAHRRAQLVRPTQAGYDAVRKIDPAHAAFAHRLTQAMGAEELEAALKAMTTLSRVLDDLDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0U6</accession>
    <name>D3Q0U6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4044</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019267.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4044"/>
    <dbReference type="EnsemblBacteria" id="ADD43696">
        <property type="protein sequence ID" value="ADD43696"/>
        <property type="gene ID" value="Snas_4044"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4044"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4978">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065103_2_2_11"/>
    <dbReference type="OMA" id="IESEGHM"/>
    <dbReference type="OrthoDB" id="1748122at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="271" mass="29398" checksum="83E3A9E2C99C6176" modified="2010-04-20" version="1">MFAIGDFARMGRVSVRMLRHYDALGLLRPARVDAGTGYRHYEAAQLARLNRIVALKDLGFTLEQVATFLDEQVSTVELRGMLRLRRAEAAAELAAARDRLTGIEARLSAIEAEGRLPSGEVVVKRVAATRVAELTAPADSYASVDITPVIRPLYSRLCRLLDDAGVTPVGPAVASYEDRGDGVLVHAAFPVPAEASERSELSVVTLPAIEAATVIHHGAMDESDASLQLLARWIDANGYRSTGYAREVNLECPPDPAQWVTELQESITAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1D0</accession>
    <name>D3Q1D0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LPXTG-motif cell wall anchor domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6086</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021281.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6086"/>
    <dbReference type="EnsemblBacteria" id="ADD45710">
        <property type="protein sequence ID" value="ADD45710"/>
        <property type="gene ID" value="Snas_6086"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6086"/>
    <dbReference type="eggNOG" id="COG3468">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_775920_0_0_11"/>
    <dbReference type="OMA" id="THEYEEG"/>
    <dbReference type="OrthoDB" id="1598574at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023849">
        <property type="entry name" value="CHP03934_TQXA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013552">
        <property type="entry name" value="Thioester_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08341">
        <property type="entry name" value="TED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03934">
        <property type="entry name" value="TQXA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048545" evidence="3">
        <location>
            <begin position="29"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="TED" evidence="4">
        <location>
            <begin position="75"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="360" mass="37915" checksum="D4933C2055D1AA4F" modified="2010-04-20" version="1">MKKTWMRAGVALTAAAALGVGLAGTAHADDEKEPVKATPTTESGWKVNGGDGSSVGQISASRIYLTTADGTKSPVYCIDIHTRLDTTHEYEEGSWEESGVANLPLVQWILHNSYPNVAPADLAEAAGADVAGLDEKTLEQAAYTATQTAIWNKTDGFKLDAADSTAEGAEIDALVTAIDKYLVESAEEMPEPTKEFTLDGPDAWDASEKSDAFKLTAPGGTAKVKAEGAKIVDENDKELSEVKSGQEFYLIPDDGAEKITLTATSEYSTPSGSVFLTTGQPVEAAKELKTDKSQRLILAKALPGETGAEWEFELDDSGTLPVTGMSLTNSLLAGAGLLLVGALAVVVMRRRRVASSWGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1H8</accession>
    <name>D3Q1H8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0105"/>
    <dbReference type="EnsemblBacteria" id="ADD39826">
        <property type="protein sequence ID" value="ADD39826"/>
        <property type="gene ID" value="Snas_0105"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0105"/>
    <dbReference type="eggNOG" id="COG0666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_429541_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="189"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="637" mass="70221" checksum="E3E9711A8533BEDD" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1J7</accession>
    <name>D3Q1J7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyruvate carboxyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0124</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HMG-CoA lyase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0124"/>
    <dbReference type="EnsemblBacteria" id="ADD39845">
        <property type="protein sequence ID" value="ADD39845"/>
        <property type="gene ID" value="Snas_0124"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0124"/>
    <dbReference type="eggNOG" id="COG0119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022138_3_2_11"/>
    <dbReference type="OMA" id="FHNTRGT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016833">
        <property type="term" value="F:oxo-acid-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043594">
        <property type="entry name" value="HMGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738">
        <property type="entry name" value="PTHR42738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="3">
        <location>
            <begin position="9"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD39845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="305" mass="32100" checksum="53E0A2AB92070813" modified="2010-04-20" version="1">MTTALPSSVSIREVGPRDGLQSENPIAVADKVRLINALSRTGLSRVEAVAFVHPRAIPQMANADEVWEAVDRNPDVRYSALVPNLKGADRALKAGFTELEVVVSASDTHNRKNINRSTDESLDALGELIATVHDGGATAEVIVATSFGCPYEGDIAASRVAWVVDRAVAAGADRVAFGDTTGMGTPRRVRELLEAVRASQPDIPILLHFHNTRGTALANVLTALEYGVTEFDASVGGLGGCPYAPGASGNLATEELVHMLHDMGIDTGVDLDALLEVAVMAEGLVGRELPSGVLRAGPRTRLTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1N6</accession>
    <name>D3Q1N6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015455.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0164"/>
    <dbReference type="EnsemblBacteria" id="ADD39884">
        <property type="protein sequence ID" value="ADD39884"/>
        <property type="gene ID" value="Snas_0164"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0164"/>
    <dbReference type="HOGENOM" id="CLU_1427216_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="190" mass="20336" checksum="95404143A30DD457" modified="2010-04-20" version="1">MSRPAVSGDVIANAIAIAGFALATWLWVFPPHSGWALVVGVVAAAVYYLGNFSRSRGGMRLLLMLVPLTYVATLITGTGMTVLEIVGETDECVVESRQSYFTGSGDGVDVTVACPGGETYRFNEARARTVEGEKVLVTYDPSGNVKANLTELQHDGLGIGFMVWTVADTALLVGLPVWIAARDRARRRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1V6</accession>
    <name>D3Q1V6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2129</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017394.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2129"/>
    <dbReference type="EnsemblBacteria" id="ADD41823">
        <property type="protein sequence ID" value="ADD41823"/>
        <property type="gene ID" value="Snas_2129"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2129"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_14_2_11"/>
    <dbReference type="OMA" id="GWCLCSQ"/>
    <dbReference type="OrthoDB" id="867226at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="2">
        <location>
            <begin position="35"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="543" mass="58873" checksum="7C25C32AD73816F6" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1Z5</accession>
    <name>D3Q1Z5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2170"/>
    <dbReference type="EnsemblBacteria" id="ADD41862">
        <property type="protein sequence ID" value="ADD41862"/>
        <property type="gene ID" value="Snas_2170"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2170"/>
    <dbReference type="eggNOG" id="COG0639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055447_1_0_11"/>
    <dbReference type="OMA" id="TAYLDYG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="8"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="374" mass="40647" checksum="33730224DCE0594A" modified="2010-04-20" version="1">MASDRALYVVSDVHGHLAKLTAALETAGLIDADRQWTGGNARLWFLGDLFDRGTDGAGVVELIMRLSTEAEAEGGVVDTLLGNHEILMLGAQRFGSEELADDEGNARNFDLWWKLNGGQDDDVANLTDKQLNWLRNRPAIVYVEDHLLVHTDTTEYASYGRNINAVNRTIRKIIKSSDAAKWWALFRRMTIRHRFEAEDGPEQAAAMLDFFGGSQLVHGHSTIPDRLGIPGEEVTGARLYCEDLVLCVDGGMYQGGPCLVVPLPVTEESLHRSTPDEEDASGYDIPTAATVAEAADAIEAELADADVDADDADGDTDAEAESDTQAEADEPTSAAEETEVDSDEPEAETEVESDGPKVKAKRLFRFADLADLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q244</accession>
    <name>D3Q244_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017482.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41911">
        <property type="protein sequence ID" value="ADD41911"/>
        <property type="gene ID" value="Snas_2221"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2221"/>
    <dbReference type="HOGENOM" id="CLU_2902062_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="62" mass="7310" checksum="14E8A17084A4C387" modified="2010-04-20" version="1">MNNFAAPEPHQYSITKTRKQTNHTFHLLMTILTCSAWAFFVWFPVILWNKLGPKPKIVTKHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2W9</accession>
    <name>D3Q2W9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021441.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6250"/>
    <dbReference type="EnsemblBacteria" id="ADD45870">
        <property type="protein sequence ID" value="ADD45870"/>
        <property type="gene ID" value="Snas_6250"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6250"/>
    <dbReference type="HOGENOM" id="CLU_2652708_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="76" mass="8260" checksum="84450C05F62E4259" modified="2010-04-20" version="1">MNTPFLPNPGDPVEALQFEIGRTHAQLDTMVRHFSYIASGRFSPAAARKILDDIRTVEADLEDITAVVATNASTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q316</accession>
    <name>D3Q316_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0268</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015557.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0268"/>
    <dbReference type="EnsemblBacteria" id="ADD39986">
        <property type="protein sequence ID" value="ADD39986"/>
        <property type="gene ID" value="Snas_0268"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0268"/>
    <dbReference type="eggNOG" id="COG3591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050832_0_0_11"/>
    <dbReference type="OMA" id="GGPWINT"/>
    <dbReference type="OrthoDB" id="1468733at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048186" evidence="2">
        <location>
            <begin position="29"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="297" mass="31125" checksum="5DFD47CD4BFE87C7" modified="2010-04-20" version="1">MRKRHLIYATLLATVGLSVAGVAGFASADPASEAERQSAKASKLDTTTDLDEYWTPERIANAKPVTAPKASRASGDSQPDGESVVIDGTKPKLKSPVDTTIGRLLFTTDDGDYICSANVVPSDNGSVLATARHCGFENNGRNYRFAPDYDSGNTPHGWWDWKSAGWTSGGDGVAFDYAFIVLNKKDGRTVQDTVGSSGIAFNNAIDRDAQITGIPGATDAVFHCNGKAYTNGNNQQLMDNCDGMSGGASGGAWLQDMDGGSGYQVGTYFGSVGSAAAGSYFGEEAREVWTGASTTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3G9</accession>
    <name>D3Q3G9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017581.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2323"/>
    <dbReference type="EnsemblBacteria" id="ADD42010">
        <property type="protein sequence ID" value="ADD42010"/>
        <property type="gene ID" value="Snas_2323"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2323"/>
    <dbReference type="eggNOG" id="COG2021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_3_11"/>
    <dbReference type="OMA" id="MWRWQRE"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="16"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="27828" checksum="C7742692D64F917A" modified="2010-04-20" version="1">MTVDLHYELTGPERAPVLVLSHALGLDAGMWTSLTARLGSRFRLLLADTRGHGGSPAPLGPYSIAELGADYLRLFDRLGLARVSWCGLSLGGMIGMWLAANAPERIDRLVLCCTASRLPPREGWTDRATAVRWAGTTAGLVDKSLDRWLSTPFRRSHPEIANRCASTLLTCDVEGYAGCCEAIGNLDLREDLSRITAPTLVLSGMDDPICTISMSATLAGSIRGASLLAVPGRHLAVVEAADRCTPALLDHLIDPEREAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3M8</accession>
    <name>D3Q3M8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4298"/>
    <dbReference type="EnsemblBacteria" id="ADD43945">
        <property type="protein sequence ID" value="ADD43945"/>
        <property type="gene ID" value="Snas_4298"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4298"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_10_0_11"/>
    <dbReference type="OMA" id="HLWVHDQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="3"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="140" mass="15311" checksum="95F92283C30C1260" modified="2010-04-20" version="1">MITIAHTQLWVHDQDVALEFYTKKLGMEVRADVTVAEMGDFRWLVVGPAGQPDTAIVLMAIPGPPVMDAKTTEQVKDLMGKGFAGTVFLGTDDCHASFKELSARGVEFVEEPEPRPYGIDSSFRDPSGNHIRLTQAYAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3S4</accession>
    <name>D3Q3S4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_4344</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4344"/>
    <dbReference type="EnsemblBacteria" id="ADD43991">
        <property type="protein sequence ID" value="ADD43991"/>
        <property type="gene ID" value="Snas_4344"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4344"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_22_0_11"/>
    <dbReference type="OMA" id="PWAWLAK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014303">
        <property type="entry name" value="RNA_pol_sigma-70_ECF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02957">
        <property type="entry name" value="SigX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="17"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="115"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="324" mass="35905" checksum="0DA9AA393BB33488" modified="2010-04-20" version="1">MLGDVSMSAVELEAFTSARPRLFAIAYRLLGSAGEAEDAVQDAFVRWQAADRERVREPVAWLTKVLTNLCLNRLTSARARREQYVGQWLPEPVLTPDDRLGPLETVEQRESMSLAFLVLLERLTPPERAAFVLREAFGYGHREIAGILDVTEAGSQQLYHRAKGHVERERSRFSATDAQARRILERFLAAASGGDLAALEEILVADAAAWADGGGQIGVARHPILGVAKVARYFANWFGNVNMERLRRLNLDHIKVYIVEANGRPAVVAYADDRLLAVMGFDLVDGRVGAVRTMANPEKLRFIGDQLDGRDRGEPLLAFSIAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q409</accession>
    <name>D3Q409_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45894">
        <property type="protein sequence ID" value="ADD45894"/>
        <property type="gene ID" value="Snas_6274"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6274"/>
    <dbReference type="HOGENOM" id="CLU_3239937_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="43" mass="4584" checksum="3144A55586B8F04D" modified="2010-04-20" version="1">MGEGLLYAPTELNELVKAAIETGYRAALTDIRNGKVEGFDVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q449</accession>
    <name>D3Q449_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LPXTG-motif cell wall anchor domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6316</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021505.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45934">
        <property type="protein sequence ID" value="ADD45934"/>
        <property type="gene ID" value="Snas_6316"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6316"/>
    <dbReference type="HOGENOM" id="CLU_735500_0_0_11"/>
    <dbReference type="OrthoDB" id="2193471at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049689" evidence="3">
        <location>
            <begin position="24"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="376" mass="40347" checksum="33C5519BBC68ED89" modified="2010-04-20" version="1">MRGICLVVGAVLVFVGTATPVAAAPVTVDVCDPASAQAKGDPTSVTLPDDGVFARGKAVALQVNDGRVVDPEDRFAYGHVPVCAILPTEDGRPEPRAEWMFCLERTKYACEDEPEYGQVDAHQFSARDRARLAWVFRDATLTTPTERAEAQSRVWCVSDKLPSRAVNTDAVEYYEKRDLTITGTCPDWDALDPTLPEDPQLDLHAVKETVKIGGTARFELTSTADPVTVTATGGKLSVCPDSGNGELDGDTLRLDTDKPVQLCVKRDRPGKVSVSAERHGIASADMEFWQYTSDPRNCQVLLRGESAPSSLHASAAARFEDNPKPSPTSSASADGDDDLPSTGTSLTWPTLLALAAMAAGIAAIVIARRMPRQPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q450</accession>
    <name>D3Q450_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell envelope-related transcriptional attenuator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6317</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6317"/>
    <dbReference type="EnsemblBacteria" id="ADD45935">
        <property type="protein sequence ID" value="ADD45935"/>
        <property type="gene ID" value="Snas_6317"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6317"/>
    <dbReference type="eggNOG" id="COG1316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016455_0_2_11"/>
    <dbReference type="OMA" id="KDMSTAY"/>
    <dbReference type="OrthoDB" id="491753at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="4">
        <location>
            <begin position="116"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="390" mass="42777" checksum="F819DB2A5A5766C5" modified="2010-04-20" version="1">MANDASDDNALEKEGTGDDAPESGAPDLAVLPAKKTKTGAPWWAKVMVGVGAVLMVAAGGGAVYAKVMLDRINNAGTEKNLLGDGDSQAGEDIKGPLNLLMIGTDMRVNDSDKIDRADSIMILHINKDLTKANIISVPRDLKVPCNDEPEGTCYTKVNGTYADGGETQEERFQGLAESLSTLTGIKQFDGAAIIGFEGFLKAVKVLGSVELCLPMDMQLHHQMKEQPNKPRTFKKGCHEYNQREALWIVRERYAYSAENPDFDPDWGVGDYGRQHMQQHFIKQLLKKASEEGYITNPTKVGDLIDAVGSTLTYHFRGHTPVDMAFALRGVKPNSMKTVRLPSETSMEGGESFEVIPEGKPLTTTEELFKALREDTMDEWIAENPKLLNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4F6</accession>
    <name>D3Q4F6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0399"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40116">
        <property type="protein sequence ID" value="ADD40116"/>
        <property type="gene ID" value="Snas_0399"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0399"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_0_0_11"/>
    <dbReference type="OMA" id="RIPNAVH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="204"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="388" mass="41805" checksum="31F39F2DD7318CF4" modified="2010-04-20" version="1">MLLNAYAMGGTVRTVFNQANALAARGHEVGVVSVMRHRRTTQFRLDPAVTLTPLVDKKLGVLRPGRSPLERIGWLRASPTRPGMEVPQQEARKRVFTRVVEKAVIRALKGCTADVLVTTRPALNLLAARYAPDGVVRVGQVHQRIKPGHTGLLDAIAADYPRLDAVVTLTRGDRAEYARMLDHRVRVARIPSPVATLHAEAADPASKVVVAAGRLVRAKGFDLLIPAFAHVVAKDPEWRLRIFGGGPMQAKLAALIEANGLEDNVVLMGRTGDLGGELAKASFCALGSRSEGLPMVVLEAFTHGLPVVSCAYPGAEELVSDGRDGILVPPEDVEELGTAMAWLATDVEARATMGERALRKARDYGPDAVAAQWEQLFTELRGAGVSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4N1</accession>
    <name>D3Q4N1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0476</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015762.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0476"/>
    <dbReference type="EnsemblBacteria" id="ADD40191">
        <property type="protein sequence ID" value="ADD40191"/>
        <property type="gene ID" value="Snas_0476"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0476"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056943_2_0_11"/>
    <dbReference type="OMA" id="PNMARMI"/>
    <dbReference type="OrthoDB" id="1036370at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="256"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="323" mass="36470" checksum="5E383F503885030A" modified="2010-04-20" version="1">MFDVFDPESDHGRVYQALVSAPRSTVDALARRTLLSPSAIRDSLTELQQFDAVTPVDSTKEVWEARRPDLVAAEAMRQFGAWRTQLLEAEERLTTAFRYARYEETSAMDFEILKGADAFFERFKVLQPSARSHVWAIDRPPYYWEPDEIHRQERMQIEQMAAGITYRTIYQESESDSPVRNASMARSVASGENARVLARPPIKMTIIDCEVGVVALDPPEGAEGSLSTLLVRRSTLLDAFCNIFESLWSLAVPVNLDRQNQELSKREREILTLMASGAGDDAIARRLGVSRRTIVRHIGRLLEHLGSTTRFQAGAQAARRGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4P7</accession>
    <name>D3Q4P7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycine betaine/L-proline ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2394</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2394"/>
    <dbReference type="EnsemblBacteria" id="ADD42077">
        <property type="protein sequence ID" value="ADD42077"/>
        <property type="gene ID" value="Snas_2394"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2394"/>
    <dbReference type="eggNOG" id="COG4175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_2_2_11"/>
    <dbReference type="OMA" id="RRGEIFC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031460">
        <property type="term" value="P:glycine betaine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005892">
        <property type="entry name" value="Gly-betaine_transp_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01186">
        <property type="entry name" value="proV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="40"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="72"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="350" mass="37810" checksum="44BF67A86DA3E550" modified="2010-04-20" version="1">MAEPDATPETATDATISIRNLWKIFGPRANKVIGTELAELDAAELKSRADTVAAVRDVSIDVKPGEMFVVMGLSGSGKSTLVRCLTRLIDPTAGQVLVEGDDVGAMGANELRDLRRHRVSMVFQHFGLLPHRRVIDNVAYGLEIQGVSRGKRRTRAQDMIDLVGLTGNEDCLPEELSGGMQQRVGLARALAVEPSIMLFDEPFSALDPLIRRDMQNEVIRLHREVGKTMMFITHDLSEALKLGDRIAIMRAGEIVQLGTPADLVGSPADDYVADFVSEVPKTDVLSLRWIARPADGVAPTGTALSADTVIRDAIGDIMAADNPLPVEADGELIGVVGQRDVLSLMAENRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4U6</accession>
    <name>D3Q4U6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FeS assembly protein SufD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017697.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2443"/>
    <dbReference type="EnsemblBacteria" id="ADD42126">
        <property type="protein sequence ID" value="ADD42126"/>
        <property type="gene ID" value="Snas_2443"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2443"/>
    <dbReference type="eggNOG" id="COG0719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026231_6_0_11"/>
    <dbReference type="OMA" id="HAVWIGD"/>
    <dbReference type="OrthoDB" id="422804at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011542">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43575">
        <property type="entry name" value="PTHR43575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01981">
        <property type="entry name" value="sufD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="389" mass="42352" checksum="3D09CFA6167CE0B5" modified="2010-04-20" version="1">MARPHSHGATPPEIVPPKTKSQLLRSFDVADFPKLNGREEDWRFTPLRRLRGLHDSSAEPATAAPKHELSAACEGVTVETVTKADKRIGSVLTPFDRVSAQAFTSASEALMIAVDRNKVVHVPVVVEVKGKGADGASYGHTFIDVGESAEVTVILDHTGSATLADNVEINVGANAHLTVVSIADWDRDSVQLQHQKARIGRDASLKHVAVTLGGDLVRQYLSAEFAGPNASIDAYGLYFAEGGQHLEHRQLVDHGVPDCRSNVNYKGALQDADAHTVWVGDVLIQDVATGTETYEINRNLVLSDGARADSVPNLEIETGEIVSAGHASATGRFDDEQLFYLQSRGIPEDEARRLVVRGFFDDLLRQVPVESLRERLHDAIERRLDRVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q538</accession>
    <name>D3Q538_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SCP2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019658.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4442"/>
    <dbReference type="EnsemblBacteria" id="ADD44087">
        <property type="protein sequence ID" value="ADD44087"/>
        <property type="gene ID" value="Snas_4442"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4442"/>
    <dbReference type="eggNOG" id="COG3255">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169722_0_0_11"/>
    <dbReference type="OMA" id="MATIEEC"/>
    <dbReference type="OrthoDB" id="1792009at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="112" mass="12139" checksum="A6B0F26A05636B8F" modified="2010-04-20" version="1">MATAEDCRNALEAFAAQIAANSDQVKRKLTFERRLACDITDLGIAFHGRFHEGRLGGITEGDDPGAEIRMTVASDDLVALINNELDFGKAFASGRVKIKASIMDLLKLKGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5E7</accession>
    <name>D3Q5E7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CDP-alcohol phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021578.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6391"/>
    <dbReference type="EnsemblBacteria" id="ADD46007">
        <property type="protein sequence ID" value="ADD46007"/>
        <property type="gene ID" value="Snas_6391"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6391"/>
    <dbReference type="eggNOG" id="COG0558">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1154461_0_0_11"/>
    <dbReference type="OMA" id="WMVNLVT"/>
    <dbReference type="OrthoDB" id="1380643at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD46007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="235" mass="24782" checksum="5CBC76CFA22E185D" modified="2010-04-20" version="1">MSRTDLRYADFLSNNRGGNLFTYVVNQRIGAFFALQAHRAGLAPTVLTLINLVFSLGAAVTIIAVAASAADGEVTWWPIAIAAAVAWQIAYSLDCSDGQLARAAGLSSPAGKRIDILCDVAAQGAFCAAVAAVAVAYSPDVPAWFIAAFASLWMVNLVTSILQTGESSGSIVTSKKLVFELVKLVRDTGVIVLLVPIVLIVYPEGMVWLMALFTVVNGLFLLASIAFTAKNALRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5E9</accession>
    <name>D3Q5E9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6393</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021580.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD46009">
        <property type="protein sequence ID" value="ADD46009"/>
        <property type="gene ID" value="Snas_6393"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6393"/>
    <dbReference type="eggNOG" id="COG2170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029030_0_0_11"/>
    <dbReference type="OMA" id="CRRRVNG"/>
    <dbReference type="OrthoDB" id="367541at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016602">
        <property type="entry name" value="UCP012666"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012666">
        <property type="entry name" value="UCP012666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD46009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="502" mass="56140" checksum="0988A8A671097E2D" modified="2010-04-20" version="1">MGDDVGIQEFTHADLKRYRHKLRRCLDALILLTDGDLFDVERTLTGMELELSLVDESGEPSMTNHEVLSHLAENAVANGDSVQDELGRFNLELNLGPRPVAGFGFETYEQRLRLWLQDVNDCARKEHSSVVMVGTLPTVRREHARLDILSRRPRYRLLNDQILSVRGEDISLDISGAETLRAHTDSIAPESVNTSVQFHLQLTPEQFPRYWNAAQAMAGVQLATAANSPYLFGTQLWAETRIILFEQATDIRNGELRVQGVRPRAWFGERWITSATDLFEENLKYFVPLLPQCVSEDPIEKVNSGEIPQLGELRLHNGTIYRWNRPVYDVGPEGPHLRVENRVVPAGPTPIDICANMAFYLGLVTALAEADMPIWTKLPFAVAEQNFHAAARHGIDAHQTWPGLGELPARVLVLDHLLPKAAEGLAALDVDSAVAERLLAIIAGRCRNGVNGAAWQVNCVQRLQQRQGLSRTPALHEMLSRYAEHAATNTPVHEWPPELKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5I1</accession>
    <name>D3Q5I1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021612.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6425"/>
    <dbReference type="EnsemblBacteria" id="ADD46041">
        <property type="protein sequence ID" value="ADD46041"/>
        <property type="gene ID" value="Snas_6425"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6425"/>
    <dbReference type="eggNOG" id="ENOG5032Y7G">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098258_1_0_11"/>
    <dbReference type="OMA" id="WLTGWNC"/>
    <dbReference type="OrthoDB" id="1911879at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021215">
        <property type="entry name" value="DUF2752"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10825">
        <property type="entry name" value="DUF2752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD46041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="154" mass="17361" checksum="A6720BB92F6E1661" modified="2010-04-20" version="1">MPTLTFPTRLRQRFPLLEPAGVLVFTVGLVTYIGVKDPNEAGHYPTCPFLMFTGFYCPGCGSLRAIHALVHFDIGTALSLNILTVCVMIPMAVFHYVRWATERYLGRSIRKRMVPASFIWALLVGLLAFWFLRNLEPLAFLAPYGVAPGDLKWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5R0</accession>
    <name>D3Q5R0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="7">1.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_0494</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015780.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0494"/>
    <dbReference type="EnsemblBacteria" id="ADD40209">
        <property type="protein sequence ID" value="ADD40209"/>
        <property type="gene ID" value="Snas_0494"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0494"/>
    <dbReference type="eggNOG" id="COG0136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049966_0_0_11"/>
    <dbReference type="OMA" id="MFDVPDE"/>
    <dbReference type="OrthoDB" id="1799040at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000319">
        <property type="entry name" value="Asp-semialdehyde_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005986">
        <property type="entry name" value="Asp_semialdehyde_DH_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01296">
        <property type="entry name" value="asd_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01103">
        <property type="entry name" value="ASD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="8">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="352" mass="36990" checksum="0610B8D99B5A2CF1" modified="2010-04-20" version="1">MSRKPTLAVVGATGAVGSVMLDVISRRADVWGEIRLIASPRSAGRKLRVRGEEVTVQAISEEVFEGVDVAHFDLPDEVSAHWVPIAAAKGVIVVDKSGYFRMDPDVPLVVAEANPEAVRNRPKGIIANANCTTLALIPSLAALNRSFGLVSMSVASYQAASGAGQAGFDSLYDQLGAVAGKRDLGTVSGDVREAIGEGGDDTFGAPLALNVVPKVGGWRPDGWTSEELKVRNESRKILDLPDLKVASTCVRVPVATGHSQAVHATFSSPVSADAARKVLAEAPGVTVVDDPDNNVYPMPIDATGRDDTLVGRIRTSIDFDNSLEFFVVGDNLLKGAALNSAQTAELLLPELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5U2</accession>
    <name>D3Q5U2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0526</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015812.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0526"/>
    <dbReference type="EnsemblBacteria" id="ADD40241">
        <property type="protein sequence ID" value="ADD40241"/>
        <property type="gene ID" value="Snas_0526"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0526"/>
    <dbReference type="eggNOG" id="COG4586">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="WWDVPVI"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="21"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="57"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="328" mass="36641" checksum="1F803919E26C0E33" modified="2010-04-20" version="1">MPLIETRALVKEFRRLRPKTGRFATVRKLFSRDYEAIRAVDGIDFAIEPGELVGYLGPNGAGKSTTIKMLTGILTPTSGDIEVAGVVPYKHRQRNARNIGVVFGQRTQLWWDLPLIDSFKLIGKLYQVPKAKYAENVERFTELLDMSSFLDTPVRQLSLGQRMRGDLAAAMLYEPPILYLDEPTVGLDVIAKERIREFIAELNADTGTTIILTTHDMDDVERLCRRLILIDHGLVLYDGPVGPLKEKYSPHRELAVQLTHPADVEVPGAEVVSHEGGAVRLSFDPTTTPVARLIAEISARYEITDLSVSEPDLEDVIRKMYAERGDTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5W8</accession>
    <name>D3Q5W8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiamine pyrophosphate protein domain protein TPP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015838.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0553"/>
    <dbReference type="EnsemblBacteria" id="ADD40267">
        <property type="protein sequence ID" value="ADD40267"/>
        <property type="gene ID" value="Snas_0553"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0553"/>
    <dbReference type="eggNOG" id="COG1013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048564_1_0_11"/>
    <dbReference type="OMA" id="GNDTWTV"/>
    <dbReference type="OrthoDB" id="981516at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPP_enzyme_C" evidence="1">
        <location>
            <begin position="55"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="341" mass="37144" checksum="654A06E5D3D843E5" modified="2010-04-20" version="1">MSEPVALTLKPKDFKSDQEVRWCPGCGDYAILAAMQSFLPSLGLEREKIAFVSGIGCSSRFPYYLNTYGMHSIHGRAPAIATGLATTRPDLSVWVVTGDGDALSIGGNHLIHALRRNVNFKILLFNNRIYGLTKGQYSPTSEVGKITKSTPAGSVDAPFNPLSLALGAEASFVARTLDSDRKHLQQVLTTAAQHEGSAFVEIYQNCPIFNDDAFEVLKNPDSRDETLIRLTHGEPITFGPEGKYAVVRNGWGIKVAETASVPPSDIVVHDETVTDPSYAFALSRLSGENLDHTPIGVLRNVKRDTYDASVRRQVEAAKPVDTTPEQELTKLLTGGDTWTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5Y2</accession>
    <name>D3Q5Y2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD-linked oxidoreductase</fullName>
            <ecNumber evidence="6">1.1.3.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0567</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; L-ascorbate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.8" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015852.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0567"/>
    <dbReference type="EnsemblBacteria" id="ADD40281">
        <property type="protein sequence ID" value="ADD40281"/>
        <property type="gene ID" value="Snas_0567"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0567"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003896_4_3_11"/>
    <dbReference type="OMA" id="YPRFGEF"/>
    <dbReference type="OrthoDB" id="482388at2"/>
    <dbReference type="UniPathway" id="UPA00132"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050105">
        <property type="term" value="F:L-gulonolactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019853">
        <property type="term" value="P:L-ascorbic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="PTHR43762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000136">
        <property type="entry name" value="LGO_GLO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0060">Ascorbate biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="21"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="435" mass="47616" checksum="FB175063979266C5" modified="2010-04-20" version="1">MRSIHFLVREGTRWTNWAGTAKTTPRRVLSPTGPDDIAKLVSEAAGRGGRLKAAGSGHSFTGIAVADDILLRLDGYRPEPVVDRETSRVTVPAGITLRELNPLLAHHGLALPNLGDIDAQTLAGATSTGTHGTGAKLNGIAAAIVGARLVDGTGTVRDFGPEDPELAAVALGLGALGVVTDLTIQCVPAFRLLAEEHPMPLDAAIAEFDTLAATNDHLDLYWFPRADRVLVKRNNRAGAGRPLSGIKRWWEDEVMSNAVYGTACHIGKTFPATVPAITSMSARLMSSRTFMDESYRVFCTPRRVRFVEMEYALPRAAFAPAFAALRGAANKRRIIFPVEIRVTAPDDLWLSTAHGRDSVYFAVHQFRGMPYRDYFAEVEAVMREHDGRPHWGKLHTRTAADLAGVYPRFADFQRLRDRLDPQRVFANSYLDRVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q616</accession>
    <name>D3Q616_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Indole-3-glycerol phosphate synthase</fullName>
            <shortName evidence="8">IGPS</shortName>
            <ecNumber evidence="8">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">trpC</name>
        <name evidence="10" type="ordered locus">Snas_2509</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TrpC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2509"/>
    <dbReference type="EnsemblBacteria" id="ADD42191">
        <property type="protein sequence ID" value="ADD42191"/>
        <property type="gene ID" value="Snas_2509"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2509"/>
    <dbReference type="eggNOG" id="COG0134">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034247_0_0_11"/>
    <dbReference type="OMA" id="RGPHDLI"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_A">
        <property type="entry name" value="IGPS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_B">
        <property type="entry name" value="IGPS_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="PTHR22854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="IGPS" evidence="9">
        <location>
            <begin position="4"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD42191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="269" mass="28560" checksum="3A9E3E41064A5513" modified="2010-04-20" version="1">MSVLDEIVAGVAADVDTRRQLIPIEKIRAIAEKTPPALDAFSILREPGVGVIAEVKRSSPSKGSLAEIPDPAELACEYAAGGARAISVLTEQNYFRGSLDDLDAVRAAVRIPVLRKDFIISSYQVHEARAHGADLVLLIVAALEQNALVSLLERVESLGMTALVEVHDEVEADRALAAGARVIGVNARDLRTLKVDTSVFERVAPGLPNGVVKIAESGVREARDLLRYASVGADAVLIGEGLVTKKSPREAVADMVTVGSHPSTPRPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q670</accession>
    <name>D3Q670_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017816.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2565"/>
    <dbReference type="EnsemblBacteria" id="ADD42245">
        <property type="protein sequence ID" value="ADD42245"/>
        <property type="gene ID" value="Snas_2565"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2565"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_2_3_11"/>
    <dbReference type="OMA" id="TEFNTSW"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="378" mass="41845" checksum="2ED0E73E1987BD6D" modified="2010-04-20" version="1">MNNTEIQRALDWAVAEVGIPGIVAHVKDGDQTWFGTAGVSDLKTGAPRRRGEHAQIGSGGKSVMAAILLGLEAEGKLSIDDPVNRWLPGVLNVNGYDGDTITIRHLLQNTAGLFATGLAPEIAHRFATRASFLKHRHHEFTTDDLFAMTVSQPPVGQPGERFLYANGGFYLAEAMIEKITGNSFAEEVEKRVIRPLRLRDTYVRPDNDTTYRDPHPRGYSRQFYKDGTDLNAVDGENWASFLEDPDLEPLDVTEFNTSWVPGNIVSTTDDMIRMVGALASGKLLPAEQHREMWTTVTTEGSNWLPYTRYGLGLFEFDPDVTGGRRLRGVGGSFWGAMFFTVSTEDGEHVISVQSNFELASWEVLQRIFEAGFGVTFTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Q8</accession>
    <name>D3Q6Q8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4658</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019872.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4658"/>
    <dbReference type="EnsemblBacteria" id="ADD44301">
        <property type="protein sequence ID" value="ADD44301"/>
        <property type="gene ID" value="Snas_4658"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4658"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_3_11"/>
    <dbReference type="OMA" id="PGVIEHR"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="3">
        <location>
            <begin position="128"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="503" mass="50704" checksum="9627BEE487D32B1C" modified="2010-04-20" version="1">MAKETHTVAPAAEADDPAGSPATDRRQGAAKPKPGAATGSAPAAERKPRTTAPAPATDEPPRTAAPKPGTLADEPPATAKPKPGTPAVGTAADAPPRTAAPKPGTSADELPATAKPKPGTPAVGAGALLQLLRDGAPRTRSELAAVTGLARSTVTQRVDALLASGLIGPSGEAASTGGRPPTTFAFKPHARVVLAADLGATHARLAVTDLAGQVLAETRADLDIAAGPQTVLDWVIEHGHALLSEIDRDPSGLLGVGIGLPGPVEHSTGRAVNPPIMPGWDGFDVPHYVGEHFTAPVLVDNDVNIMALGEHFTHWPDAEHLLFVKAATGIGCGIISDGQVFRGAQGAAGDMGHIKVAEPGPVCRCGNTGCLEAVASGAAIAAALAEQDIKAHSALDVVELARAGSVPALRLLRQAGRDIGEVLAAAVNLLNPAVIVIGGSLALAGDHLLAGVREVIYQRSLPLATQHLRIVQSRTGERAGAVGAGVMAINHGLSPSRVDALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6T8</accession>
    <name>D3Q6T8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0623</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015908.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0623"/>
    <dbReference type="EnsemblBacteria" id="ADD40337">
        <property type="protein sequence ID" value="ADD40337"/>
        <property type="gene ID" value="Snas_0623"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0623"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="HWRLAVR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="207"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="403" mass="43187" checksum="CA1D2AA96C478E05" modified="2010-04-20" version="1">MWKVLAPLLDRRTYTGWVFALLGAMCWLPAGVIALLAVLPNWPRRAEPAIFLVVLVAGVAAKGLFAQTRQGWVWLANQMLGTAIPEAGTRPLWSARLRTAVWLVVLAVSGGALMLVTGMLALTTVLLPLLWLNGGDTVTYLFADISIAAGTAGLWTIAVALAQLPVAAYLTAATAAWLRWLAPRLLGPYAAEKLVAVEERADDLARRNRLAQELHDSIGHTLTTSTIQAAVANQLMESDPASARQAMTTIEESSRQALDDLDHVLGVLRQEAATREPKYTLADVGPLLDRVAATGTTVQRHLGHGLTSIPATVSREAYRVVQEAVTNALRHAPGEPVEVTVEVSARSLGVRVVNPLPKARPNRPGRGLAGTAERVRLLHGEVTAGADEDGTHWVLSARLPLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6W1</accession>
    <name>D3Q6W1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015931.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0647"/>
    <dbReference type="EnsemblBacteria" id="ADD40360">
        <property type="protein sequence ID" value="ADD40360"/>
        <property type="gene ID" value="Snas_0647"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0647"/>
    <dbReference type="eggNOG" id="COG4315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058029_0_0_11"/>
    <dbReference type="OMA" id="CWPIYTF"/>
    <dbReference type="OrthoDB" id="1472530at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005297">
        <property type="entry name" value="Lipoprotein_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03640">
        <property type="entry name" value="Lipoprotein_15"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049738" evidence="1">
        <location>
            <begin position="32"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="295" mass="31773" checksum="095676D562720A7C" modified="2010-04-20" version="1">MSNSLLRRLALPAVIAALAIPALAACNSAGANESTGKEAADSATEVKVGETSLGDVLLDSEGKTLYMFKKDKDGKSACYDKCEKMWPPLTVDGDAKAGDGADADLLGTSEREDGSQQVTYNGMPLYYFAKDKAEGDVNGQGVKDVWYVVDAEGNIVDKAKDSGGDDGYDDGEEKKSYDLQLVDNDEYGPILVNSEGMTLYMFFKDEKLDNASACYKDCLNKWTPLTVEDDPTYGDGVDKSLIGTIEREDGTKQVTYNDWPMYTFNDDANAGDTKGVGFKDLWCATTATGEAAVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Y1</accession>
    <name>D3Q6Y1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015951.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0667"/>
    <dbReference type="ESTHER" id="stanl-d3q6y1">
        <property type="family name" value="Duf_1023"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40380">
        <property type="protein sequence ID" value="ADD40380"/>
        <property type="gene ID" value="Snas_0667"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0667"/>
    <dbReference type="eggNOG" id="COG4099">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025057_2_1_11"/>
    <dbReference type="OMA" id="YDREHAT"/>
    <dbReference type="OrthoDB" id="2018813at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010427">
        <property type="entry name" value="DUF1023"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06259">
        <property type="entry name" value="Abhydrolase_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="594" mass="63896" checksum="51932F5046D881E5" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q734</accession>
    <name>D3Q734_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0721</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016004.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0721"/>
    <dbReference type="EnsemblBacteria" id="ADD40433">
        <property type="protein sequence ID" value="ADD40433"/>
        <property type="gene ID" value="Snas_0721"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0721"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_11"/>
    <dbReference type="OMA" id="VWGWDFG"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="133"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="133"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="233" mass="26127" checksum="96BC0C4F36D6B315" modified="2010-04-20" version="1">MTQQIAHILVVEDDPNVSDVVRRYLEREGYRVTLAADGLSGLAEYRSGRPDLVVLDLMLPKLPGIEVCRALRIESEVPVIMLTALGDESDRIAGLSVGADDYLSKPFSPRELVLRVAAVLRRAVRTEAAERPGEQLTDGELILDPGSRVATLRGTKLNLTVREFDLLEFLLRHPGQVFSRAELLERVWDWTFGDQSTVTVHVRRLREKIEDAPAQPKRLVTVWGVGYRFEATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q753</accession>
    <name>D3Q753_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2647</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017895.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2647"/>
    <dbReference type="EnsemblBacteria" id="ADD42324">
        <property type="protein sequence ID" value="ADD42324"/>
        <property type="gene ID" value="Snas_2647"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2647"/>
    <dbReference type="eggNOG" id="COG3118">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090389_10_4_11"/>
    <dbReference type="OMA" id="QRVDMIN"/>
    <dbReference type="OrthoDB" id="1630944at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="30"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="120" mass="13032" checksum="FCD57E2A6AB72696" modified="2010-04-20" version="1">MATIELTEETFNSTIEADGIVLVDYWAEWCGPCKRFGPVFEAASDKHEDVVFAKVDTEAEQGIAQAANITSIPTLMAFRDGILVFAQPGALPATALDEIIGKVRDLDMDEVRAQIAAEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q760</accession>
    <name>D3Q760_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2654</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017902.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2654"/>
    <dbReference type="EnsemblBacteria" id="ADD42331">
        <property type="protein sequence ID" value="ADD42331"/>
        <property type="gene ID" value="Snas_2654"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2654"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_11_2_11"/>
    <dbReference type="OMA" id="NYGDHSG"/>
    <dbReference type="OrthoDB" id="906744at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="203"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="443" mass="48531" checksum="BF9F528C7D80E36B" modified="2010-04-20" version="1">MTDTDSQTPVPTAADEVVELCRDLIRIDTTNTGDTNTSAGERTAAEYVAAKLAEVGLEPKIYESAPGRATVVARYEGADSSRPALLLHGHLDVVPADASEWSVHPFSGEEKDGYIWGRGAVDMKDFDAMLLAVVRQWKREGRVPPRDFVLMFLADEEAAGGYGAHFMIDEHREVFDGVTEAVGEVGGFSVSVNNDLRLYMIETAEKGLDWLRLTVNSRPGHGSMIHDDNAVTQLSEAVARVGRHRFPIELTPTVRAFLEEVAEVLDIEIDYDNPEAAIAKLGPIARIIGATIRHTANPTRLEAGYKENVIPGKATATIDCRPLPGRTEEFLAQLREIIGPDIEIEHVHQQPGLETTFDGQLVDAMAESLRHFDPGARPVPYMLSGGTDAKAFHRLGIRGFGFAPLKLPADLDFSALFHGIDERVPTDGLRFGVRVLDRFLSQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7M6</accession>
    <name>D3Q7M6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4726</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019939.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4726"/>
    <dbReference type="EnsemblBacteria" id="ADD44368">
        <property type="protein sequence ID" value="ADD44368"/>
        <property type="gene ID" value="Snas_4726"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4726"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_2_11"/>
    <dbReference type="OMA" id="VHDIYPP"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025828">
        <property type="entry name" value="Put_sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13796">
        <property type="entry name" value="Sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="315"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="405" mass="43212" checksum="52C2B353022534A4" modified="2010-04-20" version="1">MRKIWQATSYLVIGGATGAVALAHLVMLVLAIVTAPLGIGIPLLSSMLGAQHGFLTQERARIGRFLGAAIGEPRRASDPAGGRRLLPQLRQATTYRESLWLLLHSAVGMPVAFGVGLLYFVAVGSWLVTVGWWVLPPGTFSFFVPITTWEQALTIPPLFAVPATAAIIWLVPAIAWAHSRLGRSLLRPTSTDRLSERVEELSHTRAEALDAHAAELRRIERDLHDGIQARLVAIGIHLGVSQRQRGDTPESADQLVDRARTGVEETLTELQAVVRGIYPPILSDRGLDGALHALAADSPVPMELTLDPPGRLPAAVEAAAYHVAAEAVTNVAKHSRATAATLRVTREANTLIIEVTDDGRGGADESGGTGIAGMRRRAAALDGRMRLASPVGGPTQLRVELPCES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7N5</accession>
    <name>D3Q7N5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4735"/>
    <dbReference type="EnsemblBacteria" id="ADD44377">
        <property type="protein sequence ID" value="ADD44377"/>
        <property type="gene ID" value="Snas_4735"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4735"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_1_11"/>
    <dbReference type="OMA" id="DWAFDHL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="20607" checksum="7BAD2786002F4EDB" modified="2010-04-20" version="1">MAHNRRMRTQVETKRLLLRPLTGDDFDDYAAMLADPEVAAGLAESTGTSAADAWRSLATFIGHRHIRGYSHFALVEKDTGRFVGRAGPWQPHGFPGLGVGWCLDRRFWGRGYATEAAHAAVRYCFTDLGATEIVSVILPGNERSATVAERVGHRFLRELTYRGQQARLYGQSADEWRARENSATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Q7</accession>
    <name>D3Q7Q7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4757</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4757"/>
    <dbReference type="EnsemblBacteria" id="ADD44399">
        <property type="protein sequence ID" value="ADD44399"/>
        <property type="gene ID" value="Snas_4757"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4757"/>
    <dbReference type="eggNOG" id="ENOG50338Q6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1776449_0_0_11"/>
    <dbReference type="OMA" id="HRIYNVA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="152" mass="16600" checksum="9A0E9CCDA72DBEBA" modified="2010-04-20" version="1">MKPKFEATAILELPLAQAEAAILDVRTGPPGQGHVWLLGDTTGAVTGGPQRFTAMLGNYRLTVDVDRERRTIATQGGWWYRGEYALEPAGPHTRVTHRVYNVAGPATRWGVPLANRLFIGFQAQTRASFADTVRDMGKRLGCRVSLPDPVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8F6</accession>
    <name>D3Q8F6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018101.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2855"/>
    <dbReference type="EnsemblBacteria" id="ADD42530">
        <property type="protein sequence ID" value="ADD42530"/>
        <property type="gene ID" value="Snas_2855"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2855"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047233_0_0_11"/>
    <dbReference type="OMA" id="VYGVWYS"/>
    <dbReference type="OrthoDB" id="1746871at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022386">
        <property type="entry name" value="Chitin_NgcE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03851">
        <property type="entry name" value="chitin_NgcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="483" mass="52822" checksum="03D7E1CAE46DFAAB" modified="2010-04-20" version="1">MSPTPNKGDLSRRRVLQGTALGAAAIPAAGLLSACATGGGGEGEDVKNSGDAKNPFDVDGSKPLDVVIFNGGFGVEYADEKTGHVSLYKKKFKKSDAKMTSQKNIKKTQMNRFADSKPADVIDNSGADKIALDTLVNDGLLAELTPLLKAPSIDDPDKTVEETLIGGALRQGTFNVDGKPKVFALPYITEGWFIWHNGALFKEKGWDVPKTWEEMLDLAKDMKKDGVAPWTFTGVHPYYLWDTLYTLAARDGGREVVQDIDNLKADAWGNASIEKAAEAMYKLQEKGYTLEGSPGLDHTKSQLKWYDGDAAFIPVGTWLPLELSNDLAKDNKKISDDFEFKATGVFAFEGSKSPDMLWLSGGEPFVVPEEAANKPGAYEYLRIMLSKEGSKVFTDATKSLSVLDGQKTDDPVASQVVALNKGPDNLHRPQVMDWYVDFKEPVEPLLTKMMKGDMKPDAFLKAAQKAADKVAANDKIDKFKQEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8P8</accession>
    <name>D3Q8P8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4849</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020061.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4849"/>
    <dbReference type="EnsemblBacteria" id="ADD44490">
        <property type="protein sequence ID" value="ADD44490"/>
        <property type="gene ID" value="Snas_4849"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4849"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_11"/>
    <dbReference type="OMA" id="AMEMIMT"/>
    <dbReference type="OrthoDB" id="1498685at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="257" mass="26747" checksum="30A2D6DDF25C5850" modified="2010-04-20" version="1">MADFVNLEVSDGIGVIRLSRPPMNALNKQVQEELRAAAIEADANDDIHAVIVYGGEKVFAAGADIKEMADMDYAAMSSRAPELSSAFDAVAKIGKPVIAAITGFALGGGCELALACDIRLCAEDAKLGQPEIKLGIIPGAGGTQRLPRLIGPAKAKELIFTGRMVDAAEAQRIGLVDEVVPAGEVFDAARKFAEVFVSGPSRALRAAKQAVDSGLGVDLNTGLAWESQLFAGLFATGDAHEGMTAFSEKRKPGFSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Q9</accession>
    <name>D3Q8Q9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4860</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020072.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4860"/>
    <dbReference type="EnsemblBacteria" id="ADD44501">
        <property type="protein sequence ID" value="ADD44501"/>
        <property type="gene ID" value="Snas_4860"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4860"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101758_3_0_11"/>
    <dbReference type="OrthoDB" id="1308416at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="163" mass="18310" checksum="36C2452245805478" modified="2010-04-20" version="1">MIKHDTASVFVFHRDPEHGWRVGLIKHPLFGVWMQPGGHVEDDETPREAALREACEETGLDGLRLVGTHRPPYLETTDTTIPMQLPVWVIEHPIPNGDNHIRDAHVHIDFKYLAVAESAEQVTTPDHPFGWFTREEVAGLDTLDDVRPIAAALFDLVEAQVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8W9</accession>
    <name>D3Q8W9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016149.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0867"/>
    <dbReference type="EnsemblBacteria" id="ADD40578">
        <property type="protein sequence ID" value="ADD40578"/>
        <property type="gene ID" value="Snas_0867"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0867"/>
    <dbReference type="HOGENOM" id="CLU_637621_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048765" evidence="1">
        <location>
            <begin position="28"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="430" mass="46135" checksum="3DC192BEA1509F04" modified="2010-04-20" version="1">MKLSKRSALIAVAGTLVVSLGVGVGLAVGESQTSALKPVYAAAQVEKEDPNRQYRAMPSLQHVSWTDGGGDHRRFIRSFLVSPDGQNPVKSRVEYQDANSVWHPALDARTKKPLMQSADAQNVSVNNVFKNSGGDLVAVELRAHNDSSGRYFYQWTSGDGGKSWKPSRSKLDMNGGAILPGAAGQSFQRVITLPDGNRVVPYYAAHKGVKGSDGKYKQTWSAAHLLVGGKDGSSWKRTATVFKSDSNTYSESSVTRRADKKLLMISRYEVVKNGLTYSKLSYRVTTSAVNSAADLAKAKWTGAKAVVVPGATDKTVVRGVAPVVHTMSGGVLMLVFGRPGNKIAFSYDGGVSWTATHDFYRNIPTNCGTGYKGHPCSDLGSSGYMGVAVTSPTSAYIMGDNCQSGWGCGGKYSYPHGTTDRLWLSLVRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q948</accession>
    <name>D3Q948_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0946</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016228.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0946"/>
    <dbReference type="EnsemblBacteria" id="ADD40657">
        <property type="protein sequence ID" value="ADD40657"/>
        <property type="gene ID" value="Snas_0946"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0946"/>
    <dbReference type="eggNOG" id="COG1134">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017703_1_2_11"/>
    <dbReference type="OMA" id="RCLHDSK"/>
    <dbReference type="OrthoDB" id="1555988at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037359">
        <property type="entry name" value="NST/OST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10605">
        <property type="entry name" value="PTHR10605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransfer_1" evidence="2">
        <location>
            <begin position="37"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="293" mass="33114" checksum="68B3F461DAD1C007" modified="2010-04-20" version="1">MIKLRTERVPAPVKRIIHSGSRAYGRLTAASRLLPGFLLCGGQRCGTTTLYRALSTHPAILKPILHKGVHFFDTGYDNGLPWYQAHFPTRAGAIRISEHTGLAAQAFESSPYYLYHPLAAERFARDLPGVKLIVLVRDPVERARSQHAHEVARGFEPHTDFEAALAAEDERLAGEADRLSWDSHYYSFSHQHHAYRARGRYTEHLERIAKVVSPERIHVVDSGEFFADPVNVYTRVLDFLGLPLLGKPNFAKHNARPRAAAKNSALDVSLSEYFEPFDARLRDWLGADPSWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q977</accession>
    <name>D3Q977_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0976</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016257.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0976"/>
    <dbReference type="EnsemblBacteria" id="ADD40686">
        <property type="protein sequence ID" value="ADD40686"/>
        <property type="gene ID" value="Snas_0976"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0976"/>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048112_0_0_11"/>
    <dbReference type="OMA" id="GKQWTDS"/>
    <dbReference type="OrthoDB" id="785253at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="249"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="470" mass="53176" checksum="DAA0B77ED278B993" modified="2010-04-20" version="1">MNNPESTSYDVRIHQIVEDKRTKKRPHRVRWTVADRPRFGKSFATVGLAEGFRSDLLRAARKGEAFDLETGLPVSMLRKQQEKQKQENTVTWLTHAKQYAAYKWTRLSANGRKSAADVLRDITVALLPQRGDRPGKDELSVALRRWAFIPARNIADAPPEIQDAFSWAERHTPALSVLEDAEVLRSLLDSLMLKQDGTRVSANYFDRRHAILYNVGEYAVMKERCEQNPLSNPKLKWERPVDLKTENVIDPRAVGTMSQVESMLTAVTYVGVEQGPRYVAYFGLLYYAMLRPAEATDLEESQCILPKEGWGLIVAKGGKPNVGQDWTDSGEAHDDRGLKHRGRKATRDVPIPPRLVELLRHHIDTYGTGPEGRVFRTVRGGPYTVKEAGRVWGKARPFGLSPADQKTDVLSYIYLLRASGISYRRAAGVPVKEVSQWAGHSTGVQEQNYARVLTGLKDHWTRRMDEFMDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9A5</accession>
    <name>D3Q9A5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2912</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018158.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2912"/>
    <dbReference type="EnsemblBacteria" id="ADD42587">
        <property type="protein sequence ID" value="ADD42587"/>
        <property type="gene ID" value="Snas_2912"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2912"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_11"/>
    <dbReference type="OMA" id="NAGIFMM"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="249" mass="25679" checksum="EC531E2AD33DCE22" modified="2010-04-20" version="1">MTRTAIVTGAARGIGAAVAARLAHDGLQVALLDLDETACADGVQRITDSGGRALAVGADVADSGAVTDAVARVAEELGPPTVLVNNAGITRDNLLFKMSEDDWDSVIGVHLRGAFLMTRAVQEFMTQRRDGRIINLSSKSALGNRGQANYSAAKAGLQGFTKTLAIELGKFGITVNAIAPGFIATDMTAATARRLGMTTEELHRAAAEQIPLGRVGTPEDIANTVSFLAGEGASFVSGQVIYVAGGPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Y9</accession>
    <name>D3Q9Y9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell division FtsK/SpoIIIE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0991</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016272.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0991"/>
    <dbReference type="EnsemblBacteria" id="ADD40701">
        <property type="protein sequence ID" value="ADD40701"/>
        <property type="gene ID" value="Snas_0991"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0991"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="EccCa-like_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023837">
        <property type="entry name" value="EccCb-like_Actinobacteria"/>
    </dbReference>
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        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="3"/>
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        <property type="entry name" value="T7SS_EccC_a"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="T7SS_EccC_b"/>
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    </dbReference>
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        <property type="entry name" value="FTSK"/>
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    </dbReference>
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    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
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            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
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        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
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        <location>
            <begin position="466"/>
            <end position="666"/>
        </location>
    </feature>
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        <location>
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            <end position="1026"/>
        </location>
    </feature>
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            <begin position="1120"/>
            <end position="1301"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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        <location>
            <begin position="741"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="489"/>
            <end position="496"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="854"/>
            <end position="861"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="1137"/>
            <end position="1144"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ADD40701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1340" mass="148314" checksum="A730E02C6F309E2C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAG2</accession>
    <name>D3QAG2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
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            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ADD42745"/>
        <property type="gene ID" value="Snas_3074"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="172" mass="18869" checksum="4FC222C3099C7E83" modified="2010-04-20" version="1">MSVVMTPEIRRRRDGDLPSCVDAMRLVHEADGYPARWPEDATGFLTPSDVLDAWVAVDGEAVVGQVLLRDGKHERDECADEEVDLPDGLASISRLFVTPAARGTGTAARLVGTCVAEARRRGLGVILSVVEGVGDASGFYERLGWRFITTRPAEWRLPNGDIPTMRYYRQPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
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    <name>D3QAP8_STANL</name>
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        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
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        <name evidence="7" type="ordered locus">Snas_5058</name>
    </gene>
    <organism evidence="7 8">
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        <lineage>
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            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
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                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5058"/>
    <dbReference type="EnsemblBacteria" id="ADD44694">
        <property type="protein sequence ID" value="ADD44694"/>
        <property type="gene ID" value="Snas_5058"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5058"/>
    <dbReference type="eggNOG" id="COG2271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_5_1_11"/>
    <dbReference type="OMA" id="RVVTTWF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="5"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="425" mass="45595" checksum="59731104F14CE991" modified="2010-04-20" version="1">MRWAIIWLAFVGLTVNYLDRASISVALPFLGEDIHLTKTQEGLILAAFFWTYDFFQLAAGWYVDKVGPRRAFTIAAVWWSIFTAVTAAVHSFWTLVAARLLLGAGESPAPATSAKVVATWFPKRERGLATGIWDSGSRVGAVIAIPLVTGIIALAGWRVTFVIIGILGLAWALGWWKAYRDPAQHPKVSAAELEYINEGGARTADNDAEGAAKLPWRKLFGYRTVRGMMLGFFCLNSVIYFFITFFPSYLVDERGFSLLKLGFFGMIPGICAVVSGWLGGWVADRAIRRGVSVTRVRKTVIVVGMVGGSVIIAAVLVPQAWMALALLSLSYASLTFAGTGIWSLPADVAPSSAHVASIGGIQNFASNFAGILTPIMVGYLVDTTGSFVIPLSVIGGIALLGALNYLFVVGRIEPLPVPAAAIAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAS9</accession>
    <name>D3QAS9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020296.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5089"/>
    <dbReference type="EnsemblBacteria" id="ADD44725">
        <property type="protein sequence ID" value="ADD44725"/>
        <property type="gene ID" value="Snas_5089"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5089"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1569739_0_0_11"/>
    <dbReference type="OMA" id="HLWHIHL"/>
    <dbReference type="OrthoDB" id="2217312at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="170" mass="18829" checksum="49917B1C565E3F12" modified="2010-04-20" version="1">MANNPDPGHITDEMWKLWETCAAAIDDVQLGGIYADKPGYHNTRAANDSGDYSVEKPADKKGPDDKAAALDLTFPEAHSGNYERIQKYTKRVVDAAEARDERMYKGDTPVIREIIGNFNGDAKAYDLYARETDSRDDSHLWHIHLSVTRQFVDDGDVLAGLADVITGEGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB20</accession>
    <name>D3QB20_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Terpene synthase</fullName>
            <ecNumber evidence="2">4.2.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1127</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the terpene synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.-" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="D3QB20"/>
    <dbReference type="STRING" id="446470.Snas_1127"/>
    <dbReference type="EnsemblBacteria" id="ADD40837">
        <property type="protein sequence ID" value="ADD40837"/>
        <property type="gene ID" value="Snas_1127"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1127"/>
    <dbReference type="eggNOG" id="ENOG502Z881">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_372108_0_0_11"/>
    <dbReference type="OMA" id="RLPLFMP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034686">
        <property type="entry name" value="Terpene_cyclase-like_2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01020">
        <property type="entry name" value="Terpene_Cyclase_Like_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="708"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="769" mass="86260" checksum="21602B16A3BE9218" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBA5</accession>
    <name>D3QBA5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translation initiation factor IF-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">infA</name>
        <name evidence="5" type="ordered locus">Snas_1212</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IF-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016493.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1212"/>
    <dbReference type="EnsemblBacteria" id="ADD40922">
        <property type="protein sequence ID" value="ADD40922"/>
        <property type="gene ID" value="Snas_1212"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1212"/>
    <dbReference type="eggNOG" id="COG0361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151267_1_0_11"/>
    <dbReference type="OMA" id="AHVSGKM"/>
    <dbReference type="OrthoDB" id="2066663at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04451">
        <property type="entry name" value="S1_IF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00075">
        <property type="entry name" value="IF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="PTHR33370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="73" mass="8529" checksum="E900C79BCB8C1E59" modified="2010-04-20" version="1">MPKKDGAIEIEGRVIEPLPNAMFRVELTNGHKVLAHISGKMRQHYIRILPEDRVVVELSPYDLSRGRIVYRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBE9</accession>
    <name>D3QBE9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PKD repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018402.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3160"/>
    <dbReference type="EnsemblBacteria" id="ADD42831">
        <property type="protein sequence ID" value="ADD42831"/>
        <property type="gene ID" value="Snas_3160"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3160"/>
    <dbReference type="eggNOG" id="COG3591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036779_1_0_11"/>
    <dbReference type="OMA" id="KVIALHH"/>
    <dbReference type="OrthoDB" id="1162936at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049853" evidence="2">
        <location>
            <begin position="30"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="396" mass="41279" checksum="B1EF19E5A8C5B6FB" modified="2010-04-20" version="1">MRAKHLLAVAAATIAAAGALAVASGTATAESQQADPAALPEPSVEKVGEHVDDPTKLSYKDSDGAVTVSHPGATYVKVNFTSLDLAPGDSLTVSAPGGTEKHTYHGAPGDGLRKTDAGYTRHGDSGFAALSVEGDTAKVTLHRSSGSTAKGAVIEGYWRGYDTKEYAKANADTRSVCDNDARRDVTCYAESRPTEYANAKPVARLLMGGSACTAFRVGNTNRLLTNNHCMSDQGTVASSETQFGYECATCGGNDPAEPTKVGGETMVSTDAGLDYTLYSVQNFDSISSFGTLYVEEREPSAGERIYIPGHGDASPKRLSIFEEEDNGTECSIQEPNLDSTNAGYMCDTSGGNSGSPVIAGDTNKVIALHHLGGCHNAGTRMALIFPEISGDIDNNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBM2</accession>
    <name>D3QBM2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018475.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3234"/>
    <dbReference type="EnsemblBacteria" id="ADD42904">
        <property type="protein sequence ID" value="ADD42904"/>
        <property type="gene ID" value="Snas_3234"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3234"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_27_8_11"/>
    <dbReference type="OMA" id="WIRRIPD"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="154" mass="17227" checksum="6C40653B44AEB490" modified="2010-04-20" version="1">MNDSVDTGILDRLLHIAVVIQQDMAATFSGTGLNPARVHLLWVLRERQPQTQQALAAALNVTPANVTGLVDALEKHGFVERRRHPEDRRAILVALTERGADTMRAMARDRELFATALVEDLDGDERRRLHDALGQVAERMEDLTRPMRESKGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBM6</accession>
    <name>D3QBM6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3238</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3238"/>
    <dbReference type="EnsemblBacteria" id="ADD42908">
        <property type="protein sequence ID" value="ADD42908"/>
        <property type="gene ID" value="Snas_3238"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3238"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="QRVLINC"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="17"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="104"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="176" mass="20378" checksum="08F69AD8E17511BE" modified="2010-04-20" version="1">MTDDPVSEFDAFARARTPALLRAAYLLTGDQHSAEDLVQSALARTMRAWKRLQRTENADAYTRKTMYHLQVRWWRRRTRERQYYQRWEQPGTVSDSSEDVGRQLELQAALRRLTAKQRAVLVLRFFEDLSVVETAEVLRCTTGTVKSQTAKALLRIRAELSHDLTTNTRSQACTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBV2</accession>
    <name>D3QBV2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5206</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020412.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5206"/>
    <dbReference type="EnsemblBacteria" id="ADD44841">
        <property type="protein sequence ID" value="ADD44841"/>
        <property type="gene ID" value="Snas_5206"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5206"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_135_1_11"/>
    <dbReference type="OMA" id="LMAIHRA"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="16"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="687" mass="72154" checksum="59C12203AB82D247" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTY3</accession>
    <name>D3PTY3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015312.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0019"/>
    <dbReference type="MEROPS" id="S12.950"/>
    <dbReference type="EnsemblBacteria" id="ADD39741">
        <property type="protein sequence ID" value="ADD39741"/>
        <property type="gene ID" value="Snas_0019"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0019"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_11_2_11"/>
    <dbReference type="OrthoDB" id="1439085at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="416" mass="45990" checksum="CEFA833EDEE6B0DF" modified="2010-04-20" version="1">MTNLNSTEIKTDNDSGFSDAGLRRLRGVLERHVDSGKIPGLVALVSRDGHTHVETLGTMRHDGGAPMRRDTIFRVASIAKPVTMAAAMILLDECRMRLDEPVDEWLPELANRRVLKRPDGPLDETVPANRPITVRDVLTCTFGLGVDFELMTAPIRAAIFEATDYGVGSGPAPGFDEWMRRLGELPLSYQPGERWQYDLPSEVACVLVSRVAGQPFGQFLRERVLEPLGMKDTGHHVPDGEIHRLPPLYGPDPQTGEFLVWDEAEGGRVSQAPEFEGTALVSTVDDYHAFFRMLLNGGTHQGRRILSRPAVELMTTNRLTPEMNSARDDMYRAILHLSNGQGLHGGWGLGMAVRTRRGDYAPVGQFGWDGGTGTSVYADPHHRLTGMLFTQVGMSTLDSVRLIQDFWTTTYQAIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUC4</accession>
    <name>D3PUC4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1363</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 25 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016641.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1363"/>
    <dbReference type="CAZy" id="GH25">
        <property type="family name" value="Glycoside Hydrolase Family 25"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41070">
        <property type="protein sequence ID" value="ADD41070"/>
        <property type="gene ID" value="Snas_1363"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1363"/>
    <dbReference type="eggNOG" id="COG3757">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044973_4_0_11"/>
    <dbReference type="OMA" id="IDWTHRY"/>
    <dbReference type="OrthoDB" id="1444566at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002053">
        <property type="entry name" value="Glyco_hydro_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018077">
        <property type="entry name" value="Glyco_hydro_fam25_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01183">
        <property type="entry name" value="Glyco_hydro_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00641">
        <property type="entry name" value="Glyco_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51904">
        <property type="entry name" value="GLYCOSYL_HYDROL_F25_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049462" evidence="4">
        <location>
            <begin position="38"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="251" mass="27206" checksum="ACEC36D22238BE86" modified="2010-04-20" version="1">MDTPYPKYRSMRTFTTLLLSLVLAATLLAFGAGPAQADPEVKANPEGIDVSHYQGAINWGAVRSAGIEFAWIKSTEGTSYKDPRFNTNYPAAHAAGVIRGAYHFARPGSSSGATQANYFASSGGAWSADNLTLPGALDLEAGCHGLSQTAMRNWILDFYNTYKSRTGRDVVIYTTRSWWTSCTGNWTGMGTRSPLWVAHWGVSSPAIPVGFPTWTAWQFTDNGRVNGISGAVDRNHFNGSRDRLLALANNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUN0</accession>
    <name>D3PUN0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018614.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43043">
        <property type="protein sequence ID" value="ADD43043"/>
        <property type="gene ID" value="Snas_3379"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3379"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="LQPMYSL"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="325" mass="35330" checksum="B4C13006026B3D51" modified="2010-04-20" version="1">MKYVRLGSTGLEVSRLCLGCMSFGEPDRGADTWTLGTEDSRAIIRDALEAGINFFDTANVYSDGSSEEIVGAALRDMGRRDELVIATKVFGAMRPGPNGGGLSRKAILTEIDASLRRLGTDYVDLYQIHRWDANTPIEETLEALHDVVKAGKARYIGASSMYAWQFAKALFTADAYGGTRFVTMQNHYNLLNREEEREMLPLCLDQGIGSLPWSPLARGRLARPVGVETRRTGDDAFGDSLYKGYDDADRAIIDGVGQVAETRGVSRAQVSLAWLASRPAVTAPIVGVTKPGQLADALGAIDIELTEAEVDQLERPYVPHPVAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV26</accession>
    <name>D3PV26_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent Clp protease ATP-binding subunit ClpX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">clpX</name>
        <name evidence="10" type="ordered locus">Snas_1372</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the ClpX chaperone family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1372"/>
    <dbReference type="EnsemblBacteria" id="ADD41079">
        <property type="protein sequence ID" value="ADD41079"/>
        <property type="gene ID" value="Snas_1372"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1372"/>
    <dbReference type="eggNOG" id="COG1219">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014218_8_2_11"/>
    <dbReference type="OMA" id="HYKRVQA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00175">
        <property type="entry name" value="ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004487">
        <property type="entry name" value="Clp_protease_ATP-bd_su_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046425">
        <property type="entry name" value="ClpX_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010603">
        <property type="entry name" value="Znf_CppX_C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038366">
        <property type="entry name" value="Znf_CppX_C4_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06689">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00994">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00382">
        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51902">
        <property type="entry name" value="CLPX_ZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ClpX-type ZB" evidence="9">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="412"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="468"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="506"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="550"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD41079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="567" mass="62785" checksum="737EFE4B00169A3C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV35</accession>
    <name>D3PV35_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BRCT domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1381"/>
    <dbReference type="EnsemblBacteria" id="ADD41088">
        <property type="protein sequence ID" value="ADD41088"/>
        <property type="gene ID" value="Snas_1381"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1381"/>
    <dbReference type="eggNOG" id="COG0272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_333130_0_0_11"/>
    <dbReference type="OMA" id="FRHEEDE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="22"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="925"/>
            <end position="946"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1024" mass="111535" checksum="295602A9561B0B9F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV55</accession>
    <name>D3PV55_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MDMPI_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1401</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016679.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1401"/>
    <dbReference type="EnsemblBacteria" id="ADD41108">
        <property type="protein sequence ID" value="ADD41108"/>
        <property type="gene ID" value="Snas_1401"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1401"/>
    <dbReference type="eggNOG" id="ENOG5030J62">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051661_2_0_11"/>
    <dbReference type="OMA" id="WTGMTRA"/>
    <dbReference type="OrthoDB" id="2055578at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017520">
        <property type="entry name" value="CHP03086"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03086">
        <property type="entry name" value="TIGR03086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="2">
        <location>
            <begin position="6"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="194" mass="20893" checksum="7507C04519855721" modified="2010-04-20" version="1">MSIDLTASTQHVAALLSGVRDEHLTAPTPCGEYTVAALLDHIMGFSSAFTWIARKQDEGLSDDPPHARAEDLDPRWRELLPGRLTELGEAWRDPAADEGQARAAGVELPRSVWRLVALNELLVHGWDLATATGQPYRTDPAAVAVTVEFMGQDADDPASRENNPAFGPIVTVPDDAPAIDRAVGLSGRDPGWKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV58</accession>
    <name>D3PV58_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Propeptide PepSY amd peptidase M4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1404</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1404"/>
    <dbReference type="EnsemblBacteria" id="ADD41111">
        <property type="protein sequence ID" value="ADD41111"/>
        <property type="gene ID" value="Snas_1404"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1404"/>
    <dbReference type="eggNOG" id="COG3212">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1348248_0_0_11"/>
    <dbReference type="OMA" id="GQQWETT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025711">
        <property type="entry name" value="PepSY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03413">
        <property type="entry name" value="PepSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048394" evidence="2">
        <location>
            <begin position="35"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="PepSY" evidence="3">
        <location>
            <begin position="140"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="20567" checksum="19A729B3C77FD65F" modified="2010-04-20" version="1">MIATMRTRNVISAVGAAALSVVLLGACGDGDDDAGDNDKDDSTSASASGDDGAASPDPNVGSGAKIAVAAMDTAAADVKGGKVLDLDRDDDSGGQQWETTVAEGTKAEYELRVSADGTKVESNNKDNDLDEDLAQLADAKLSAQDAAKRAAKDHPGDVTGVDFDVPDGGGDPTWQVTLNDNGSATEYTLDADSGKTLNSEADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV76</accession>
    <name>D3PV76_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016700.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1423"/>
    <dbReference type="EnsemblBacteria" id="ADD41129">
        <property type="protein sequence ID" value="ADD41129"/>
        <property type="gene ID" value="Snas_1423"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1423"/>
    <dbReference type="eggNOG" id="ENOG5033H5V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139199_0_0_11"/>
    <dbReference type="OrthoDB" id="1949654at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="129" mass="14176" checksum="225D7CA0387DA69A" modified="2010-04-20" version="1">MINPRPGVALVAVEPSGELYFSANIVVTTDALPTATELERWQDDSDGELELRLPDYVLLDRETTADGRVRRLAHYEQPDCGPVTMEQWAWLYDGIGYTITASVATPAYDGLADVFARVAEGFTPGEVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV97</accession>
    <name>D3PV97_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PINc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1444</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016721.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1444"/>
    <dbReference type="EnsemblBacteria" id="ADD41150">
        <property type="protein sequence ID" value="ADD41150"/>
        <property type="gene ID" value="Snas_1444"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1444"/>
    <dbReference type="eggNOG" id="COG1848">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119496_3_0_11"/>
    <dbReference type="OMA" id="FWTADEE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="PINc" evidence="4">
        <location>
            <begin position="3"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="145" mass="15682" checksum="82866AE9EBF3BC43" modified="2010-04-20" version="1">MIVYADSSVLVRAYLPDEAGHDKARSLLEDPELVVVSGTWTRVEVTGALVRAARAHRGQPQKLVAAWETDIGPDGAITLLTARQRDIERHALEIVKGDGLRAMDAWHVACAALTVIELADGETCGFATRDQAQAEVAARFGFMTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVC0</accession>
    <name>D3PVC0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016744.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41173">
        <property type="protein sequence ID" value="ADD41173"/>
        <property type="gene ID" value="Snas_1469"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1469"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060131_7_0_11"/>
    <dbReference type="OMA" id="MTRHHHL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="22299" checksum="0F22A88EDA32F34F" modified="2010-04-20" version="1">MRTEQRYGTKAEKKRIIAAQREAFADEAVVRWVTSDPARREKLDATYVEYMVTDALKHDEVLLAVTDEGRIVGVSIWQTFDSAKRPAELAAEVAALSASVPGLDRVATVTRLIAEHHPDKPHLYLSSMGVVPDHRGKGVGSALLRHRLAAADAAGQAAYLEASTPSSRDLYARHGFVQREPDIALPDDGPRLHPMWREPGTGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVR3</accession>
    <name>D3PVR3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3514"/>
    <dbReference type="EnsemblBacteria" id="ADD43177">
        <property type="protein sequence ID" value="ADD43177"/>
        <property type="gene ID" value="Snas_3514"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3514"/>
    <dbReference type="HOGENOM" id="CLU_1947514_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049281" evidence="1">
        <location>
            <begin position="33"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="129" mass="13654" checksum="46E9655AE7CF9637" modified="2010-04-20" version="1">METTLRKKKTLIAIAGVALTAAGVVGGYTAVADTSSKASCVGASSCTKTFTVTKGVDLHVYVDAEAGANNEVQWSVSPNVEGSPHCGGKMRVDDPPFQPTCSNYPYSIAHVTVWDPTMTTHTYEARAWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW10</accession>
    <name>D3PW10_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Succinyl-diaminopimelate desuccinylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5500"/>
    <dbReference type="EnsemblBacteria" id="ADD45131">
        <property type="protein sequence ID" value="ADD45131"/>
        <property type="gene ID" value="Snas_5500"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5500"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_1_0_11"/>
    <dbReference type="OMA" id="SWTDAIN"/>
    <dbReference type="OrthoDB" id="906744at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009014">
        <property type="term" value="F:succinyl-diaminopimelate desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010174">
        <property type="entry name" value="Succinyl-DAP_deSuclase_DapE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01900">
        <property type="entry name" value="dapE-gram_pos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="169"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="358" mass="38516" checksum="7A78F0B899EF75B9" modified="2010-04-20" version="1">MVVLTEAQLTDPVALTRALVDIESVSGDEREITDAIEAALRHRAHLTVERIGNVVCARTEFGRGRRVLLAGHTDTVPLHDNFPSRTEGDIMYGCGTSDMKSGTAIALHLAATLTEPAHDLSFIFYDCEEIESDRNGLGLLAKSHGHLLEADLAFLLEPSHGELEAGCQGTMRAEVRTHGKRAHAARGWLGDNAVHKAGDILDRLRAYEARTVDIDGCVYREGLNAVRIQGGVAGNVIPDECVVEVAFRFAPDRSEDQARAHVAEIFAGFDIDVTDSAPAAPPGLSAPAARDFLDTLGRPPVAKLGWTDVARFSALGIPAVNYGPGDPNLAHTKDEHVSCERIVQCADTLRDYLTGEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW30</accession>
    <name>D3PW30_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5520</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5520"/>
    <dbReference type="EnsemblBacteria" id="ADD45151">
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        <property type="gene ID" value="Snas_5520"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:transmembrane transporter activity"/>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="entry name" value="EmrB-like"/>
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        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
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    </dbReference>
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        <property type="entry name" value="SSF103473"/>
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    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
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    </dbReference>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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    </feature>
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        </location>
    </feature>
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    </feature>
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    </feature>
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        <location>
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    </feature>
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            <end position="382"/>
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    </feature>
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            <begin position="434"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="471"/>
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    </feature>
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        <location>
            <begin position="32"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="502" mass="52676" checksum="9F362ABB50FCBDE1" modified="2010-04-20" version="1">MTDSAYEKSGVATLEAPAVEAAKPTGKRARRVIWLLLSAAFVMILNETIMAVALSELMDDLNVVARTAQWLTTAFMLTMAVVIPITGFLLQRFNTRPIFMGAMGFFSLGTLTAASAPGFEVLLAGRILQACGTAVIIPLLMNTIMTLVPAAERGKMMGNISIVISVAPAIGPTISGVILSVLDWRWMFLLILPIALVATYIGYLRIENVGEPKRVPIDVFSVVLSALGFGGLLYGLSQIGGGAEGGTDGGAQPSPMPMWIALGVGLVSLVVFVLRQIRLQREDRALLDLRTFKSMNFSVSIGMIMISMGTLFGTVILLPIYTQKVLELSPLFTGLLLLPGGLVMGLMGPIVGRIFDRFGPRVLLVPGALIMTVIMVLLTFVGEDTSPYSLLAGHMLLSAGLAALMTPLFTAGLGSVRPDLVPHGSAILATSQQVAGAAGTALFVTVMAIQVAASTAGGASEATALTEGVRAAFFVGIITSVLAVIAAFFVRKPEEAPEGAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWD1</accession>
    <name>D3PWD1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1585"/>
    <dbReference type="EnsemblBacteria" id="ADD41288">
        <property type="protein sequence ID" value="ADD41288"/>
        <property type="gene ID" value="Snas_1585"/>
    </dbReference>
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    <dbReference type="eggNOG" id="ENOG5032XDT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113280_0_0_11"/>
    <dbReference type="OMA" id="HHENDRV"/>
    <dbReference type="OrthoDB" id="1589996at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="173" mass="18791" checksum="F9DF96B0A409CA06" modified="2010-04-20" version="1">MSNPDGGVIDPDAPMDETDMANLTAVREMYDQIDPMPVGLVDRLRFAVALEHMDAEVARLVEQDALAGVRASVGLAEEARTIIFESKTVTVMVSVTPAGDDVVRVDGWLTPEGPYNVEVRTPDTQFRTDADVTGRFVVAELPRGVFRMVIRPTPEQLEKGASPVVITPSVVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWF5</accession>
    <name>D3PWF5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1609</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1609"/>
    <dbReference type="EnsemblBacteria" id="ADD41312">
        <property type="protein sequence ID" value="ADD41312"/>
        <property type="gene ID" value="Snas_1609"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1609"/>
    <dbReference type="eggNOG" id="COG2268">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3064">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_402193_0_0_11"/>
    <dbReference type="OMA" id="MVMFLAR"/>
    <dbReference type="OrthoDB" id="1442240at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="222"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="293"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="358"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="554"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="593"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="237"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="297"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="370"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="419"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="452"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="554"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="617"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="652"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="684" mass="73243" checksum="FD0109706A585805" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWK2</accession>
    <name>D3PWK2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3562"/>
    <dbReference type="MEROPS" id="S12.950"/>
    <dbReference type="EnsemblBacteria" id="ADD43224">
        <property type="protein sequence ID" value="ADD43224"/>
        <property type="gene ID" value="Snas_3562"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3562"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_11_2_11"/>
    <dbReference type="OMA" id="WRYGHST"/>
    <dbReference type="OrthoDB" id="1439085at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="394" mass="42072" checksum="7A627A29C7F4DC14" modified="2010-04-20" version="1">MGGFSSKGLARVRELLERLVESGFVPGAAVVVARHGEVHLEATGQLAFEGAGSTTPMAGDTICRMTSMTKPIVAACAMTLVDDDTLRLDDPVDDLLPELADMRVLADPDGPLDATVAANRPTTPRDLLTFTLGTGMVLAEPGTVPIADALDTLGEPPPDEWIRRLGALPLVHQPGERWLYDTGADVMGVLIARAAGKSLGDALRERIFDPLGMRDTAFSVDGDNLGRFATAYERDNAATGEPVVDDRPDGQWSRPPVFASGGSGLVSTAHDYLAFATALLAGGVHRGERVLSRQSVESMTTDHLTPAHKAVSGFWPGYFDTMGWGFGMSVITGHSDHGHSVGSYGWPGKYGTAWYNDPAKDLTAIVVMQRSHAGDQRLPMWLDLWTAVHQATDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWN1</accession>
    <name>D3PWN1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3593</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018824.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3593"/>
    <dbReference type="EnsemblBacteria" id="ADD43253">
        <property type="protein sequence ID" value="ADD43253"/>
        <property type="gene ID" value="Snas_3593"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3593"/>
    <dbReference type="eggNOG" id="COG1239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1240">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029430_0_0_11"/>
    <dbReference type="OMA" id="LLDHTCR"/>
    <dbReference type="OrthoDB" id="1143438at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="573" mass="61494" checksum="8DEDAF9E2D8B4DA6" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWW5</accession>
    <name>D3PWW5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020760.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5558"/>
    <dbReference type="EnsemblBacteria" id="ADD45189">
        <property type="protein sequence ID" value="ADD45189"/>
        <property type="gene ID" value="Snas_5558"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5558"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_51_0_11"/>
    <dbReference type="OMA" id="TAWNDVI"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="4"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="227" mass="24208" checksum="07FD6DAE07C509FD" modified="2010-04-20" version="1">MRELILIHGFGSSSRAWAPQREALSQRFRVTAVDLPGHGARAADGFDLDAAVSAVREHVTDGAHVLGISGGATVAMLVALAEPGRLGSLLLSAPVAAPPASLAVQRTVMRLTPEPLLRNMMAKLYSGNRQRYRETAKRDFARCGKANLLAALAAIAELDLRDRLSDIDAPTLVVCGTRDRENLAPSTVVANGIPSATLHEIPGVGHLWNLEEPELFNRTVVDFAAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWY0</accession>
    <name>D3PWY0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5573</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020775.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5573"/>
    <dbReference type="EnsemblBacteria" id="ADD45204">
        <property type="protein sequence ID" value="ADD45204"/>
        <property type="gene ID" value="Snas_5573"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5573"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="WVVNAYF"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="13"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="474" mass="48771" checksum="A16B531429CDF7C3" modified="2010-04-20" version="1">MPIERQRGSRLPALVVLCFVQFMLVLDDNVVSVALPSIKSELGFSTAGLAWVVNAYFLAFGGLLILFGRMADLLGRRRVFLAGVVLFGAASLLCGLAREPWQLVAGRFVQGAGSAMASPAAMSLLTLLFPGVRERARAIGIWGGVAALGAISGLVISGVLTGLTGWRWVFFINLPVALVALVLVPRLLDESRASRGGRLDVPGAVLGTGAVLSLVYALLRAGETQWTDATVLAALGSALALAVAFVVVESRTAEPLLPLAFVSVRVRAVGNGLTLVFSAAMYAMAFLLMIHLQMVLDYEPLTAGIAYLPYGAAILSGMWLSARVVERFGLRRTLIASFLVTAAGLLLLSGVDASDGYLAGVLPGMLVTALGNGLSLPALSVAAVTGTTGENAGLGSAVFSSVQQIGGAVGVSVLVTLAARQSAAAAQAGPATAATEGFSFALVVAAALLAVAAIVIPDLRERSCASSRPSTLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX06</accession>
    <name>D3PX06_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020801.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5600"/>
    <dbReference type="EnsemblBacteria" id="ADD45230">
        <property type="protein sequence ID" value="ADD45230"/>
        <property type="gene ID" value="Snas_5600"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5600"/>
    <dbReference type="eggNOG" id="COG0410">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="TGDMAME"/>
    <dbReference type="OrthoDB" id="1475841at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="235" mass="25199" checksum="F5518DEE29EE4E83" modified="2010-04-20" version="1">MSDELLRVDGLHVSYGRVRAVRDVSFTAPRGELISLVGANGAGKSSVLGAVSGLVRPKSGTVHYDGANITRWPAHRRVAAGMVLVPEGRQILTTLTVAENLLLGGWRRRRAAATIAEMYELFPVLAQRRDLSAGTLSGGEQQMLAIARAMVAQPRVLLMDEPSMGLSPKLVDEVFRVIETIRATGVTIVLVEQNARRALRAADTGYVLETGVVSHSGPAPRLLADRRVVDAYLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX47</accession>
    <name>D3PX47_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FtsX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5641</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5641"/>
    <dbReference type="EnsemblBacteria" id="ADD45271">
        <property type="protein sequence ID" value="ADD45271"/>
        <property type="gene ID" value="Snas_5641"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5641"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_360826_0_0_11"/>
    <dbReference type="OMA" id="DLGVCKA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="640"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="692"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="748"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="285"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="780" mass="80537" checksum="A931FB06AEE6372E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX67</accession>
    <name>D3PX67_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016901.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1627"/>
    <dbReference type="EnsemblBacteria" id="ADD41330">
        <property type="protein sequence ID" value="ADD41330"/>
        <property type="gene ID" value="Snas_1627"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1627"/>
    <dbReference type="eggNOG" id="COG4989">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_8_1_11"/>
    <dbReference type="OMA" id="VVYAWVM"/>
    <dbReference type="OrthoDB" id="1367386at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="16"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="309" mass="33949" checksum="7DE0CFC1F1E85851" modified="2010-04-20" version="1">MKTLSFPNSKVPASNIVLGLMRIGTLTDEAIRALVGTARDTGITVFDHADIYGSERHQCEARFGEAMALTATERESMIIQSKVGIREGYFDFSTEHILRSVDETLAALRTDYLDVLLLHRPDTLVEPDEVAAAFDQLHQAGKVRDFGVSNHTPGQIELLKTAVRQPLIANQVQLSITHAPMIASGIAANMSGLDQSIDRDNGILDYSRLHGMTLQAWSPFQKGFFDGVFLGDRENYADLNDAIDELAAKYEVTPTGIAVAWITRHPANMQVVLGTTNPTRVADSAAGSDIPLTREEWYRLFRTAGHTVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX96</accession>
    <name>D3PX96_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016930.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1657"/>
    <dbReference type="EnsemblBacteria" id="ADD41359">
        <property type="protein sequence ID" value="ADD41359"/>
        <property type="gene ID" value="Snas_1657"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1657"/>
    <dbReference type="eggNOG" id="COG1075">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_530918_0_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="9"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="513" mass="57620" checksum="0BA517676CE778EA" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXE2</accession>
    <name>D3PXE2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1706"/>
    <dbReference type="EnsemblBacteria" id="ADD41405">
        <property type="protein sequence ID" value="ADD41405"/>
        <property type="gene ID" value="Snas_1706"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1706"/>
    <dbReference type="eggNOG" id="ENOG50348RK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068054_0_0_11"/>
    <dbReference type="OMA" id="WINMEGE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="351" mass="38276" checksum="571DF8F8290AEBD5" modified="2010-04-20" version="1">MTYAEENPSVDKAVEERFRRLLRAYPAWYRKQRGEEMLTTLMDASDGRDRPTAGQRADVVFGGLRKHLSAGSIPAAVVGVFVAVFVATLGAIGGSIAAWNTAVDLPDGAAADQLARQAVPEMGTDVYDYRHRDLFGWINMEGEPIDSLFAIADGDGYHAGRLAYEVEHKKDGYARLDEARDRLPGAGWDVGAVKSSDMEKSFSATRDGLVMEVRTAEFPDYPWYTEVDISRATPNLVPVLTVVGLIVGAVAGWMLTSWLARRVRPWSINRRAAMTGPLAFGGFILSFPTAICLYLVYTSLANPDDRVPVWSGFIWGPMAVVTMGGLGFVILGFLLGLAPKAKRRRVAQVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXH7</accession>
    <name>D3PXH7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017011.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1742"/>
    <dbReference type="EnsemblBacteria" id="ADD41440">
        <property type="protein sequence ID" value="ADD41440"/>
        <property type="gene ID" value="Snas_1742"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1742"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_11"/>
    <dbReference type="OMA" id="RFREHWL"/>
    <dbReference type="OrthoDB" id="1752728at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="13"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="314" mass="32823" checksum="D9212A46D41E9061" modified="2010-04-20" version="1">MTDMRVVTQDELGGPEVLRLATAPVPEPGPTEILVRVEAAGLNPVDTKIRRGGGFMGEPPFTLGWDVSGVVEAIGPGVRRFDVGDEVLGMPGFPRKGRDGAYAEYVIGGSRQFAHKPEALTHVEAAGLSLAGLTAWQALVDLGGIRKGHTVLIHAAAGGVGHLAVQIAAAHGAHVIGTASAPKHDFVTSLGAAEVIDYTAVDFTEVVSDMDIILDTVGGEYGPRSLDVLKPGGVFVPLPSPHDPKLTALAAERGVDARQLLVEPDRADLEALTALVVAGKLRVHVARSFPLADVVEAHRELETGRTKGKLVLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY22</accession>
    <name>D3PY22_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="6 12">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Snas_5721</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 12">
            <text>a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9517"/>
            <dbReference type="Rhea" id="RHEA-COMP:9527"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>a dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:9517"/>
            <dbReference type="Rhea" id="RHEA-COMP:9527"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="6 12"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020922.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5721"/>
    <dbReference type="CAZy" id="GT39">
        <property type="family name" value="Glycosyltransferase Family 39"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45351">
        <property type="protein sequence ID" value="ADD45351"/>
        <property type="gene ID" value="Snas_5721"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5721"/>
    <dbReference type="eggNOG" id="COG1928">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021079_0_0_11"/>
    <dbReference type="OMA" id="AGNHHPW"/>
    <dbReference type="OrthoDB" id="1171867at2"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="GlyclTrfase_39-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="Glyco_trans_39/83"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="PTHR10050"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="238"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="406"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="PMT" evidence="14">
        <location>
            <begin position="46"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_4TMC" evidence="15">
        <location>
            <begin position="321"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF16192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ADD45351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="508" mass="56955" checksum="E3EE2BB578F4C7F8" modified="2010-04-20" version="1">MSAAAVDAPVRPPADPTDPVPARLRARLSPWRPTNRLQGWLIAGLVTAFGAALRLVGLTHPKGLIFDEVYYAQDAKQLLDHGVEWDVETANGSYVAHPPLGKWCIALGEWLFGYDEFGWRISSAVAGIISILLITLLARRLTGSTVLGAVAGLLVSMDGMHLVLSRTALLDIFLMLFLLAAFYCLVLDRESRRSRWLAALSSGLDPTKKSPPFQFPWWRVAAAVLSGCAMGVKWSALWFIILFLILIFVWEWQLRRLVGTRTPILDALVTEIGWLFTFGIVSILTYLATWTGWFATDNGYFRHWLADSGSSEPPVLGALVNLWHYHTDVLSFHDGLSSPHTYQSWPWQWILDIRPVVFFWSSDVDCGAPECASEVLLLGTPLLWWAFIPALIALVWWGLSNRDWRAWAIFGAAFAGIAPWLLYPDRTMFSFYALPAVPFLVLALTVTLGLIIGPRTATPERRLSGSLIAAGIVILIALCFAYFWPLYTGQIMTNDDWHARIWLEDRWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY38</accession>
    <name>D3PY38_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020938.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5737"/>
    <dbReference type="EnsemblBacteria" id="ADD45367">
        <property type="protein sequence ID" value="ADD45367"/>
        <property type="gene ID" value="Snas_5737"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5737"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055817_1_1_11"/>
    <dbReference type="OMA" id="VLPGWFQ"/>
    <dbReference type="OrthoDB" id="1060221at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043917">
        <property type="entry name" value="DUF5753"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19054">
        <property type="entry name" value="DUF5753"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="276" mass="31479" checksum="FFA51D5AF8482238" modified="2010-04-20" version="1">MLLGAHLRRLREAEGISRSDAGWEIRASDSKISRLELGRVSFKIRDVEDLLTFYGVDDEEERAELLKLAEEANTPGWWHRFGDVLPGWFQSYLGLEATASLIRTYENQFIPGLLQTKAYARGVVLLGHGRASAREVDHRVDLRTSRQQILHRENPPRVWTVVDEAALRRPIGGKQVMREQLEHLIEVSKAPHIQIQIIKFEAGGHAAAGGPFTMLRFPDQELPDIIYIEQLTSALYLDKRDDVDLYTASMERLCVQAEEPKKTPEILREIIGQLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY49</accession>
    <name>D3PY49_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WD-40 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020949.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5748"/>
    <dbReference type="EnsemblBacteria" id="ADD45378">
        <property type="protein sequence ID" value="ADD45378"/>
        <property type="gene ID" value="Snas_5748"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5748"/>
    <dbReference type="eggNOG" id="COG2319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_860288_0_0_11"/>
    <dbReference type="OMA" id="DLESSEW"/>
    <dbReference type="OrthoDB" id="1872254at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="220"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="279" mass="29669" checksum="0BCBF3F2A080B0C8" modified="2010-04-20" version="1">MSTPLISSLPASCDHIVDFDLVTVGGRVLLVGSPDRDRLVCTWDPASDRWTRYELDVPAEEFPHTELTSLGAAVVDGRIVIGGGGDHQGFVLWDPSDAGPEDDSVVDIEELECRSGTSSAAAAGLWTGRPVVVAGGSDGGVLVWDIEEERPLAEFDDLDEELTEFALASVDGRTRVVAAGENSVVLGDLESSEWGERMTVPGGEISCLTAATVHGRPFAVTGASDGTIRVWDLAGCRLLGQPQGHNSEVFGVRIADLDSRPVLISSAHRDPVHLWEFPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY76</accession>
    <name>D3PY76_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017014.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41443">
        <property type="protein sequence ID" value="ADD41443"/>
        <property type="gene ID" value="Snas_1745"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1745"/>
    <dbReference type="HOGENOM" id="CLU_2467516_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="88" mass="9689" checksum="836C01F41EBFE8F2" modified="2010-04-20" version="1">MRVLDLYTGEERFRAGARVPLGQEVSGNGVQAAETVPRAGEKRYLFEGSDVDDRWLNDHALSLLDEDLLLDVYAYAAAGDDGEETKCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYP7</accession>
    <name>D3PYP7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secD</name>
        <name evidence="12" type="ordered locus">Snas_3824</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019051.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3824"/>
    <dbReference type="EnsemblBacteria" id="ADD43480">
        <property type="protein sequence ID" value="ADD43480"/>
        <property type="gene ID" value="Snas_3824"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3824"/>
    <dbReference type="eggNOG" id="COG0342">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007894_4_2_11"/>
    <dbReference type="OrthoDB" id="121331at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01463_B">
        <property type="entry name" value="SecD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005791">
        <property type="entry name" value="SecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01129">
        <property type="entry name" value="secD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="490"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="518"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="569"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="594"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="MMPL" evidence="11">
        <location>
            <begin position="469"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="141"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="148"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD43480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="656" mass="70535" checksum="17F8DFA371C65784" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYZ4</accession>
    <name>D3PYZ4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020994.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5793"/>
    <dbReference type="EnsemblBacteria" id="ADD45423">
        <property type="protein sequence ID" value="ADD45423"/>
        <property type="gene ID" value="Snas_5793"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5793"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_5_2_11"/>
    <dbReference type="OMA" id="THVLRHW"/>
    <dbReference type="OrthoDB" id="1677723at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="139" mass="15430" checksum="5B7E49F0064334CB" modified="2010-04-20" version="1">MKSTELNVTLTIGEAAARFGLATHVLRHWESMGLLSPRRNGDRRRYGEEDLYRIALVVRGKQAGLSLEDIAELHQARGGAARKQILRQQRTALLKRIAEAQAALELIDHGLGCPHEDLLECTKFRHSVAELVDLTVPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ22</accession>
    <name>D3PZ22_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021022.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5821"/>
    <dbReference type="EnsemblBacteria" id="ADD45451">
        <property type="protein sequence ID" value="ADD45451"/>
        <property type="gene ID" value="Snas_5821"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5821"/>
    <dbReference type="eggNOG" id="COG1507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097805_1_0_11"/>
    <dbReference type="OMA" id="IAHRCPC"/>
    <dbReference type="OrthoDB" id="1922611at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007511">
        <property type="entry name" value="DUF501"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37163">
        <property type="entry name" value="PTHR37163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04417">
        <property type="entry name" value="DUF501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="18185" checksum="44F95FDDA1DAFDD9" modified="2010-04-20" version="1">MDQISDADRDSIAAQLGRPPRAVNSIAYRCPCGNPAVTETLPRLEDGTPFPTTFYLTCPKASGAIGTLEASGLMKEMTERLRDDPELAARYREAHESYLEHRAKLGEVPEIDGVSAGGMPDRVKCLHVHLAHSLVAGRGVNPFGDEARDLIGEWWAAGPCVATTEARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ82</accession>
    <name>D3PZ82_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021082.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5883"/>
    <dbReference type="EnsemblBacteria" id="ADD45511">
        <property type="protein sequence ID" value="ADD45511"/>
        <property type="gene ID" value="Snas_5883"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5883"/>
    <dbReference type="eggNOG" id="COG2372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055269_1_1_11"/>
    <dbReference type="OMA" id="VHDKPMH"/>
    <dbReference type="OrthoDB" id="1271038at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="303" mass="32043" checksum="C6B8D5E4EEC19F03" modified="2010-04-20" version="1">MRLPKPPPGLKPLLPLVVGAVVVALLAGVVIGRLLPASAGAPVETQAESSASADGGHTHGGGSTEESEPADLEGLSLSASGFTLVPKDTEVGQSGEAKPWAFTITDVEGEPITKFATLHDKKMHLFAVRRDFTGYQHLHPVMDPDSGLWSTDITFDTPGGWRVIADFAVGGGKDVTPATLGTDVTVPGDYEPAALPEPKTTAKTDSFDVTLDFKPELGASAPALIEVTKDGKAADLERYLGAHGHLVLLRQDDMGFAHVHPDSKRVDGELRFWATVPSKGDYRAFLDFKVDGKVRTAAFTITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ93</accession>
    <name>D3PZ93_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent Clp protease adapter protein ClpS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">clpS</name>
        <name evidence="4" type="ordered locus">Snas_1871</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds to the N-terminal domain of the chaperone ClpA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1871"/>
    <dbReference type="EnsemblBacteria" id="ADD41567">
        <property type="protein sequence ID" value="ADD41567"/>
        <property type="gene ID" value="Snas_1871"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1871"/>
    <dbReference type="eggNOG" id="COG2127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153743_1_0_11"/>
    <dbReference type="OMA" id="RDVQAMH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00302">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022935">
        <property type="entry name" value="ClpS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33473">
        <property type="entry name" value="PTHR33473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049389" description="ATP-dependent Clp protease adapter protein ClpS" evidence="2">
        <location>
            <begin position="37"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="ClpS" evidence="3">
        <location>
            <begin position="43"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="119" mass="13322" checksum="856C4A75BEDAE5B0" modified="2010-04-20" version="1">MGQVSAQPSPTFTRRLPRCVLGVSAKVARPETVTDAAETPEADAPWVTIVRNDPVNLMSYVSYVFQSYFGYTRPKAEELMLDVHNKGLAVVSSGNREEMERDVQAMHGYGLWASMRQDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZF0</accession>
    <name>D3PZF0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1928</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1928"/>
    <dbReference type="EnsemblBacteria" id="ADD41624">
        <property type="protein sequence ID" value="ADD41624"/>
        <property type="gene ID" value="Snas_1928"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1928"/>
    <dbReference type="eggNOG" id="COG5632">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_705776_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14488">
        <property type="entry name" value="CBM6-CBM35-CBM36_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033803">
        <property type="entry name" value="CBM6/CBM35/CBM36-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015510">
        <property type="entry name" value="PGRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006619">
        <property type="entry name" value="PGRP_domain_met/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11022">
        <property type="entry name" value="PTHR11022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00701">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGRP" evidence="3">
        <location>
            <begin position="69"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="2">
        <location>
            <begin position="79"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="391" mass="41508" checksum="2CBD1CBB8CC8AB29" modified="2010-04-20" version="1">MAISDILRRPLISNPYPREFEFMPSVPQASRRNVIRGALVVGVAGAAGGGALLTANLAQAENDAKAKAPEIFSCEDWGARPGSGSQLSNKPTKIVIHHTASANQSDTSKQAAFKLAKDVQSWHMDGNGWSDTGNNFTISRGGFIMEGRHTSLKHLNDGKGWVQSAHAPGANSDGIGIENEGTYTDGLPPKELWNALVQFCAHACKQFGIAPKEIYGHRDFSSTACPGEAFYAKLPQLRKDVEAALNGDGGGGGDDAWTAVVDNGDKDVKRGEGWKLSAYSADKHGKDYAFAEPGNGGGLVEFTVTIPKDGTYTVSTWYAANKGYNPKAPYTVHAGGTDKAVTVDQTAKGGQWVSLGDYKLKKGKQKLVSVGHKTTGKGYVIADAIQVKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZF1</accession>
    <name>D3PZF1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1929</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017196.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1929"/>
    <dbReference type="EnsemblBacteria" id="ADD41625">
        <property type="protein sequence ID" value="ADD41625"/>
        <property type="gene ID" value="Snas_1929"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1929"/>
    <dbReference type="eggNOG" id="COG3023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037559_0_1_11"/>
    <dbReference type="OMA" id="FNHRTAG"/>
    <dbReference type="OrthoDB" id="1584918at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015510">
        <property type="entry name" value="PGRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006619">
        <property type="entry name" value="PGRP_domain_met/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11022">
        <property type="entry name" value="PTHR11022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00701">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="PGRP" evidence="4">
        <location>
            <begin position="43"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="3">
        <location>
            <begin position="55"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="223" mass="23532" checksum="1AE5788A13D527BF" modified="2010-04-20" version="1">MSPIPPTSRRNLLRGAIVVGAGTAVGGAALLTTSVAHADAKAPEITSCADWGAREPSGELTQLDANPTKIVIHHTASGNSGGEDQESSNAFAREVQSWHMDGNGWSDTGQHFTVTRGGFALEGRHTSLQHLTDGAGFVQGAHSPGANTDGVGIENQGTFTDSLPPEALYNKLVELCAYICTQWGIDPKEIYGHRDFYNTECPGQAFYDQLPKLREDVAAAVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q043</accession>
    <name>D3Q043_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5945</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5945"/>
    <dbReference type="EnsemblBacteria" id="ADD45572">
        <property type="protein sequence ID" value="ADD45572"/>
        <property type="gene ID" value="Snas_5945"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5945"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058822_0_0_11"/>
    <dbReference type="OMA" id="AGYPAMW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="363" mass="36943" checksum="11419D6DE02B0C1D" modified="2010-04-20" version="1">MCPVFLVGGLSVQIGQELHFTPSGLGLAVASYFTASALASFWAGRLVERMGSKFVAKAAILLAAGSLAAIAVAARDLTSLTLLLVLAGPANSLGQLSSNALLARKVPPKRRGLMFGVKQAAIPLSTTLAGLAVPIVALTVGWRWGFGVAAVLALLAWPVLPRTEEAGPQPGRPKPQLRPNATLVVISLAACLGATAANPVGSFIADYGVSQGMSESLSGLNLTLGGLAGVAARTTVGWMADRRDSGRLVMIAVMLAVGSAGLALLAAPGVWTIPIGTVAGFALGWAWPGLLNFAITLRYSQAPAAATGITQIGVYIGGGLGPLAFGALVDAWGYPVGWLTMAVLMLAGAVLMIVGRRMLLTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0E1</accession>
    <name>D3Q0E1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0083</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0083"/>
    <dbReference type="EnsemblBacteria" id="ADD39805">
        <property type="protein sequence ID" value="ADD39805"/>
        <property type="gene ID" value="Snas_0083"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0083"/>
    <dbReference type="HOGENOM" id="CLU_131550_3_3_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="2">
        <location>
            <begin position="21"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="79" mass="8609" checksum="C3195424825D19A4" modified="2010-04-20" version="1">MTRRTSSCRRGDTRGAARAVPWRKSSYSDNSGGNCVEARVSVLPQVRDGKLGDDSPLLTLDEATFRGLLHQIKTGAFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0I7</accession>
    <name>D3Q0I7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-6 adenine-specific DNA methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017294.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2028"/>
    <dbReference type="EnsemblBacteria" id="ADD41723">
        <property type="protein sequence ID" value="ADD41723"/>
        <property type="gene ID" value="Snas_2028"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2028"/>
    <dbReference type="eggNOG" id="COG4325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032303_1_1_11"/>
    <dbReference type="OMA" id="YVQHIDM"/>
    <dbReference type="OrthoDB" id="1749489at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018723">
        <property type="entry name" value="DUF2254_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10011">
        <property type="entry name" value="DUF2254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="431" mass="47124" checksum="864D3FB962FB4E71" modified="2010-04-20" version="1">MAEGARRPRSPLYDHLRDNFWFAPLVALAGAVVGAQLAVRLDEFVIELADTWRDTELLYLLQAVNKSTRGIISSVTGAMLTFVGVVFSISLVALQMASSQFSPRVLRLYIRSRITKATLSVGLATFLFSLLVQLGFDDSDITTTASVPLFSSLGSVALVVTSLVLFVFYVNATLRLLRVNHVLAELATETLRVIAARRFEPRDHAFDAEVAATVRFTGGRSGVLRDVNLPRLIRLARKHDTVIEVVPKVGDFLTTGTPAIKVHGGRTPELWRVRGCLSVGSERSPRQDVGFGVRQIADIGIRALSPAVNDPTTAVAAIDRLLQILAGLVSRPDSHSWYRDRAGRLRLMVPEPSVAGLLDTAFTEFRVYGAGSPQVTRRLLSALDDLAAIAIDAHRPAIRRHRRLLMTAVAATTSRSDEREFALTPDRQGIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Q1</accession>
    <name>D3Q0Q1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017358.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2093"/>
    <dbReference type="EnsemblBacteria" id="ADD41787">
        <property type="protein sequence ID" value="ADD41787"/>
        <property type="gene ID" value="Snas_2093"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2093"/>
    <dbReference type="eggNOG" id="ENOG5032X4A">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1160583_0_0_11"/>
    <dbReference type="OMA" id="LPDYPMW"/>
    <dbReference type="OrthoDB" id="1264156at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="242" mass="26278" checksum="C2801C0A48DD193A" modified="2010-04-20" version="1">MSDGFDVAEAVGGGIVDRQRAWAFVRDFASAWGAPLSDADATPAAELARAEAALGLRFPAALREAHALFGARLDLVSNLDPLLTPDEVFVHDGLGGVLVYRSENQGCAFWGVRLEDLHLDDPPVFVEARHGWVRFMDRLSVAIVELVLSEALIGDGRLCDASELSADLVGVAGERFRRVALPDYPMWTGAEDYPVRWFSAPGKLLRQDGLGVGCVLHVRGRTRGDLEAICQTIPGQWRWGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q152</accession>
    <name>D3Q152_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4151</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019373.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4151"/>
    <dbReference type="EnsemblBacteria" id="ADD43802">
        <property type="protein sequence ID" value="ADD43802"/>
        <property type="gene ID" value="Snas_4151"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4151"/>
    <dbReference type="eggNOG" id="COG4586">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="VEGPRQW"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="18"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="321" mass="35293" checksum="66CB4A156BD593DD" modified="2010-04-20" version="1">MNTVIDVRDLRKEFTVRVKKGRLTREKKTVAAVDGVNLTVERGEMIGYIGPNGAGKSTTLKMLTGVLNPSAGHVRVCGLEPVPQRLKLTRRIGVVFGQRSALWWDLPLRESFDLLRHVFDIPAAEHAARLNRCRGLLELDEFLDTPVRQLSLGQRMRGELTAALLHGPEILFLDEPTIGLDVVSKQSVRSFLAELGAGGDVTLVLTTHDLADIEKLCKRLVVIDHGHVVHDGTLEELHDRYGSRRQVIADFEADWDEALTPPGSHAVIDAEDPRRVVFSLSNGDASAGELVARLATTAALRDVSIVEPDIEDVVAKLYTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1A5</accession>
    <name>D3Q1A5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylmuramic acid 6-phosphate etherase</fullName>
            <shortName evidence="2">MurNAc-6-P etherase</shortName>
            <ecNumber evidence="2">4.2.1.126</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">N-acetylmuramic acid 6-phosphate hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">N-acetylmuramic acid 6-phosphate lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">murQ</name>
        <name evidence="4" type="ordered locus">Snas_6061</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-acetyl-D-muramate 6-phosphate = (R)-lactate + N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:26410"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58722"/>
            <dbReference type="EC" id="4.2.1.126"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-sugar metabolism; N-acetylmuramate degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.126" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021256.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6061"/>
    <dbReference type="EnsemblBacteria" id="ADD45685">
        <property type="protein sequence ID" value="ADD45685"/>
        <property type="gene ID" value="Snas_6061"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6061"/>
    <dbReference type="eggNOG" id="COG2103">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049049_1_1_11"/>
    <dbReference type="OMA" id="CPPTFCT"/>
    <dbReference type="OrthoDB" id="1100044at2"/>
    <dbReference type="UniPathway" id="UPA00342"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016835">
        <property type="term" value="F:carbon-oxygen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046348">
        <property type="term" value="P:amino sugar catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097173">
        <property type="term" value="P:N-acetylmuramic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05007">
        <property type="entry name" value="SIS_Etherase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00068">
        <property type="entry name" value="MurQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005488">
        <property type="entry name" value="Etherase_MurQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040190">
        <property type="entry name" value="MURQ/GCKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10088">
        <property type="entry name" value="PTHR10088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10088:SF5">
        <property type="entry name" value="PTHR10088:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13580">
        <property type="entry name" value="SIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00274">
        <property type="entry name" value="TIGR00274"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SIS" evidence="3">
        <location>
            <begin position="63"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="307" mass="31454" checksum="1F326AA5AEE6D9A5" modified="2010-04-20" version="1">MTESEALVQQLRGLSTEGSDPRFATIDQMSSRELAAVMNTTDAEVPRAIAGQLDAIAAAIDAVVERMARGGRLRYVGAGTAGRMAVVDASECPPTYSTPPELIQAVLAGGGAAMTNSVEGAEDDADAGAAAMAAHDIGPDDVVVGVTASGRTPFVIGALTEAGRRGALTVGLSCNGDAELSKVVEHGLEVVVGNEVVAGSTRLKAGTAQKLVLNMISTITMVRLGHTHGNYMVDMRVLNEKLAARAARMVAEITGADLTTAAETLGRAGNHIKSAIVMIEHDVDADTARERLAAAGGRLSKALANKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1Q9</accession>
    <name>D3Q1Q9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid adenylation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0188</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015478.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0188"/>
    <dbReference type="EnsemblBacteria" id="ADD39907">
        <property type="protein sequence ID" value="ADD39907"/>
        <property type="gene ID" value="Snas_0188"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0188"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_0_9_11"/>
    <dbReference type="OMA" id="LFDFWSH"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020459">
        <property type="entry name" value="AMP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00154">
        <property type="entry name" value="AMPBINDING"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0045">Antibiotic biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="509"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1538"/>
            <end position="1613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="482"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="579"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1613"/>
            <end position="1638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1623"/>
            <end position="1638"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="544"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="1573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD39907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1638" mass="176449" checksum="53D30E9ED7D3C447" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1R6</accession>
    <name>D3Q1R6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Aspartate 1-decarboxylase</fullName>
            <ecNumber evidence="9">4.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Aspartate alpha-decarboxylase</fullName>
        </alternativeName>
        <component>
            <recommendedName>
                <fullName evidence="9">Aspartate 1-decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="9">Aspartate 1-decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="9" type="primary">panD</name>
        <name evidence="14" type="ordered locus">Snas_0195</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H(+) + L-aspartate = beta-alanine + CO2</text>
            <dbReference type="Rhea" id="RHEA:19497"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="EC" id="4.1.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 10">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="9 10">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; (R)-pantothenate biosynthesis; beta-alanine from L-aspartate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterooctamer of four alpha and four beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="9 12">Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PanD family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.11" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015485.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0195"/>
    <dbReference type="EnsemblBacteria" id="ADD39914">
        <property type="protein sequence ID" value="ADD39914"/>
        <property type="gene ID" value="Snas_0195"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0195"/>
    <dbReference type="eggNOG" id="COG0853">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115305_2_0_11"/>
    <dbReference type="OMA" id="HEPKLVF"/>
    <dbReference type="OrthoDB" id="1751990at2"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00002"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004068">
        <property type="term" value="F:aspartate 1-decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006523">
        <property type="term" value="P:alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06919">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00446">
        <property type="entry name" value="PanD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003190">
        <property type="entry name" value="Asp_decarbox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21012">
        <property type="entry name" value="PTHR21012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02261">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006246">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00223">
        <property type="entry name" value="panD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 9 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 9" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="8 9 10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 10" id="KW-0704">Schiff base</keyword>
    <keyword evidence="5 9" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5011837823" description="Aspartate 1-decarboxylase beta chain" evidence="9 13">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011837824" description="Aspartate 1-decarboxylase alpha chain" evidence="9 13">
        <location>
            <begin position="25"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9 11">
        <location>
            <begin position="73"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid" evidence="9 10">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9 10">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9 11">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser)" evidence="9 12">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD39914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="141" mass="14878" checksum="AD078F22392C7420" modified="2010-04-20" version="1">MFRTMLKSKIHRATVTHADLHYVGSLTVDENLMEAADLLPGEQVAVVDITNGARLETYVIPGQPGTGVIGINGAAAHLVKPGDLVILIAYAVMDEEHSRGYAPKIVHVNGDNEIIDLDVDPAAVAPGVAGEPRRSPLAKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1T0</accession>
    <name>D3Q1T0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015499.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0209"/>
    <dbReference type="EnsemblBacteria" id="ADD39928">
        <property type="protein sequence ID" value="ADD39928"/>
        <property type="gene ID" value="Snas_0209"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0209"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_38_0_11"/>
    <dbReference type="OMA" id="RVTVYGH"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="195" mass="20761" checksum="339DC785C92AB2EE" modified="2010-04-20" version="1">MTSSDSRPRRRADAERSIARIVAAARTTLGDNPDATIDDIAKAAGVGRMTLYGHFKNRADLVEAALVDALRAGEERLSAVDLSGDARDALARLLASSWSLVAESNALLEAAQPILPTERIRQLHAAPAERVEGLIRRGQSQGVFRTDLPNTWLVNAVFYLVHGAADENRAGRLAGTEAAAVITGTVQSMLATPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q238</accession>
    <name>D3Q238_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphate ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2214</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017476.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2214"/>
    <dbReference type="EnsemblBacteria" id="ADD41905">
        <property type="protein sequence ID" value="ADD41905"/>
        <property type="gene ID" value="Snas_2214"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2214"/>
    <dbReference type="eggNOG" id="COG1117">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="AFMYMGD"/>
    <dbReference type="OrthoDB" id="1416748at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="49"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="81"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="304" mass="32794" checksum="2F1CBFD11DDD1305" modified="2010-04-20" version="1">MSHLSSARPAAGTPATGGRTSAPRITAPTAGLGSGAPVSAEGGNAHPVMDLSDVSVFYGQVEAVRGVTMPIRHNQITAMIGPSGCGKSTVLRSLNRMNDLIAGARVAGSITYHQQDIYGANVDPIQVRRHIGMVFQKPNPFPKSIYDNVAYGPRLDGVKKRAELDLVVEEALTGAALWDEVKDKLKTSGLALSGGQQQRLCIARTIAVKPEVILMDEPCSALDPIATSKVEDLMYRLAENYTIVIVTHNMQQAARVSHYTSFFTAEVDDAGVRHGRLVEFDDTQKIFTNPSEQRTEDYITGRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2D7</accession>
    <name>D3Q2D7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Terminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019441.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4221"/>
    <dbReference type="EnsemblBacteria" id="ADD43870">
        <property type="protein sequence ID" value="ADD43870"/>
        <property type="gene ID" value="Snas_4221"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4221"/>
    <dbReference type="eggNOG" id="COG4626">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036719_0_0_11"/>
    <dbReference type="OMA" id="KGWGKDP"/>
    <dbReference type="OrthoDB" id="1527109at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005021">
        <property type="entry name" value="Terminase_largesu_Lambdalike"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03354">
        <property type="entry name" value="Terminase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="526" mass="58112" checksum="C7448AAC8BC8CE6E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2L2</accession>
    <name>D3Q2L2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021334.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6140"/>
    <dbReference type="EnsemblBacteria" id="ADD45763">
        <property type="protein sequence ID" value="ADD45763"/>
        <property type="gene ID" value="Snas_6140"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6140"/>
    <dbReference type="HOGENOM" id="CLU_747848_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="370" mass="38334" checksum="A56D640AE201D9D3" modified="2010-04-20" version="1">MYPESQSPQPQDDQELFTQLYHGGQDPDQLDEDEQRKADVIKTVNAGVSASAAGGAAAASAMILGQQTAGAGAAGAGAGAMGSGGTAATLVKGGMGLKVMLGAAAGVVVVSGVVVVGVNVLDRGGAGTPDAAPISEAAMDEGIEKFDFENATFTDEAGSEVELTDGRFLPPGLPEDSNEGYHLNATEYADVDGDRDLDAAILLEWQPNAGHTTSYVYLWLWDGDKATQVEYPVTNGYYSSVGGLKAAKNGFTVETTAAPPDISSNDEPVKETITIGVEDGFPVQIEPVFGSADRCPEFPDFPATGPYEDVIPKVAPDDDAPDIGKAEDIKSVHAVWTDRSQAFQGEWMAARVERADGSISCGWIPADAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2U8</accession>
    <name>D3Q2U8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6228"/>
    <dbReference type="EnsemblBacteria" id="ADD45849">
        <property type="protein sequence ID" value="ADD45849"/>
        <property type="gene ID" value="Snas_6228"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6228"/>
    <dbReference type="eggNOG" id="COG0503">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1377397_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="198" mass="21064" checksum="CE4B18A6DD242094" modified="2010-04-20" version="1">MTAAEAARRRLRETTVWSGDRLATLHWWSDAELLRLLGPALAELHAPSEANLVAGAQSSGYLLAPLTATTLGVGMLGIQKLPRPDGSITLATATEMPGPGDRVLLVDDVVETGAQALAIRDLVTSTGAEWLGAAAMVTYRDVPGLNLKALVHIDELRYGSFLDLVVDLCAKPAMLGSLTAIDPEPRSVSCLNLDRRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2W3</accession>
    <name>D3Q2W3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6243"/>
    <dbReference type="EnsemblBacteria" id="ADD45864">
        <property type="protein sequence ID" value="ADD45864"/>
        <property type="gene ID" value="Snas_6243"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6243"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061176_0_0_11"/>
    <dbReference type="OMA" id="TWFLGRA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="75"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="335" mass="36519" checksum="1D7D34D6F145E4B5" modified="2010-04-20" version="1">MKLLVLGGTWFVGRAIVEEALDRAWNVTTFNRGQSGRGVVGAVNVHGDRTCVGDIQGLAEYGPWDALVDTSGYVPRNVLNVASSLLSQVNRYVFMSTVSVYKGWPAEALSEQSDLLHCPPDADSSYGEDVEDGPTRYGYQKSGCESAVTEVFGESRSLLLRPGVVLGPREYVGRLPWWLRRIAKGGPTLAPGSAERRIQPVDVRDLAEFTVQAIEDRQHGAFNIAANGSETFGGLLNACIATTHSSAELIWMSDDRLLAAGVRQWSEMPLWRTAPGTWAVAAAKAQRAGLRSRPLVETVGATWEWMNTSPEIAANERSIEIGIDFSKEQAILGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Y1</accession>
    <name>D3Q2Y1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0232"/>
    <dbReference type="EnsemblBacteria" id="ADD39951">
        <property type="protein sequence ID" value="ADD39951"/>
        <property type="gene ID" value="Snas_0232"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0232"/>
    <dbReference type="eggNOG" id="ENOG502ZGSX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1721233_0_0_11"/>
    <dbReference type="OrthoDB" id="1812163at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="152" mass="17214" checksum="CD254F1A04E79333" modified="2010-04-20" version="1">MRHPVGVNQPDDNGQPQPPDGFDPRQNPRGLMTDGRRVADPADFGRGPRGGDFPQTVFRNERPPVQRHHREQTTDEYEETARSMASHPLFRGLLQELPPRTAPPSQEWLDRWSSTARSILELLYSRDPLALDRRLASALNGVLTREGGRTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Z6</accession>
    <name>D3Q2Z6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0248"/>
    <dbReference type="EnsemblBacteria" id="ADD39966">
        <property type="protein sequence ID" value="ADD39966"/>
        <property type="gene ID" value="Snas_0248"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0248"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_2_1_11"/>
    <dbReference type="OMA" id="IGMHRVA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="146" mass="16045" checksum="CF6975B85CB81773" modified="2010-04-20" version="1">MTLKKLDNIEIIVEDLDAVIAFFTELGMEVEGRSQVEGSWAARLVGLEDQKVDVAMMRVPGDNGRVELAQYRMPDAIRSLPENAPPHTLGIRRIMFAVEDLDGKVAHMLAHGAELVGEVVRFGDSYKLAYLRGPEGILVALAEELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q321</accession>
    <name>D3Q321_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015562.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD39991">
        <property type="protein sequence ID" value="ADD39991"/>
        <property type="gene ID" value="Snas_0273"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0273"/>
    <dbReference type="HOGENOM" id="CLU_1936839_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049667" evidence="2">
        <location>
            <begin position="27"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="130" mass="13861" checksum="825DAB7758122E5C" modified="2010-04-20" version="1">MKLLTGTLLAGAACLSVLAGCSSPEAKDDSSKSDSSLAKFTGSWQNEEAGTELTVKDSGKVTLTGWGEESTLTSELTADKTDGVAAFDVDGSDKTPFHFVVEFRNSESDQIYLDDTNETDVPPLEMTRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q323</accession>
    <name>D3Q323_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemolysin-type calcium-binding region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015564.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0275"/>
    <dbReference type="EnsemblBacteria" id="ADD39993">
        <property type="protein sequence ID" value="ADD39993"/>
        <property type="gene ID" value="Snas_0275"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0275"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114502_0_0_11"/>
    <dbReference type="OMA" id="GALNCER"/>
    <dbReference type="OrthoDB" id="220144at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048189" evidence="1">
        <location>
            <begin position="38"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="20995" checksum="9141A7B7FE089FFE" modified="2010-04-20" version="1">MFTPPTLRSSLRIVARASLVATLAAVGVAASAYGAYASSPEPESLQCTLSGTASSDTLFGTNGDDVLCAFGGNDVIYGAGGNDIILAGAGDDQVFGQGGMDTIYGEGGYDVIYGGNGADNVYSGAQADQIYGNNGADTLYGQGGNDVIRGQAGDDYLVAGNGNNWLYGGNGFDTLHAANGYIDHVDGGAAYDTCYFDYFDSVVNCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q397</accession>
    <name>D3Q397_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DnaB domain protein helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0349</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015638.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0349"/>
    <dbReference type="EnsemblBacteria" id="ADD40067">
        <property type="protein sequence ID" value="ADD40067"/>
        <property type="gene ID" value="Snas_0349"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0349"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020866_3_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025048">
        <property type="entry name" value="DUF3987"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13148">
        <property type="entry name" value="DUF3987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DnaB" evidence="3">
        <location>
            <begin position="4"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="666" mass="72111" checksum="A2EAE8CAE0F7D72D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3D0</accession>
    <name>D3Q3D0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017542.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2282"/>
    <dbReference type="EnsemblBacteria" id="ADD41971">
        <property type="protein sequence ID" value="ADD41971"/>
        <property type="gene ID" value="Snas_2282"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2282"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_5_0_11"/>
    <dbReference type="OrthoDB" id="1772343at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="113" mass="11965" checksum="25C9CBCCC7C8906C" modified="2010-04-20" version="1">MSPTLQAQPDAAITAKARTLAPQLKALGDETRLTLLLLLAERPRSVRELTDATGLSQTLVSHHLTPLREQGLITATPKGRSNIYSVCCDEIAVPVQMLAGLADTARGCETGCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3I6</accession>
    <name>D3Q3I6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2341</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017598.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2341"/>
    <dbReference type="EnsemblBacteria" id="ADD42027">
        <property type="protein sequence ID" value="ADD42027"/>
        <property type="gene ID" value="Snas_2341"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2341"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_0_11"/>
    <dbReference type="OMA" id="HINAIFD"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="144"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="215" mass="23783" checksum="92C419139DFCCFC8" modified="2010-04-20" version="1">MRVILAEDSTLLREGLSRLLAEEGHEVVGSFGDAITLLPAVAKTEPDIVVVDVRMPPTHTDEGLRAALRIRRDHPDVGVLILSQHVEKRFTVELLSGDINGVGYVLKDRVVRVEEFLDALERVGDGGSAFDPEVVRQLLSRTSHGDPLATLTDREREVLELMAEGHTNDAIAKRLFVSRSAVEKHVNAIFTKLELTANTDGYSRRVLAVLRYLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3L7</accession>
    <name>D3Q3L7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017629.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2373"/>
    <dbReference type="EnsemblBacteria" id="ADD42058">
        <property type="protein sequence ID" value="ADD42058"/>
        <property type="gene ID" value="Snas_2373"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2373"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_905895_0_0_11"/>
    <dbReference type="OMA" id="RALWWGR"/>
    <dbReference type="OrthoDB" id="1581296at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="159"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="307" mass="33064" checksum="EA9EFC4D70720F1F" modified="2010-04-20" version="1">MLFRPAIESDLDRVLSFGSNDPLSWPGVDRHRDGIADGSWSLSNTWLALDGDTLVAMARFWAPSPTEAPAAMDGLYTDASVPDRAGLAADLLTHAHEAIGKKPEYHMFLSSQWRDDTPVADAVAWRLEALAKVGMTDELERLRYKWTPEAGVPDPDPRLEFRPADDAAFLDAFCKVSAGSLDVGTQQGIAAHGVEAEAREHMGVYLEMPGDRSWWRLAYDANGSLVGLAIPSANNGGPVVGYLGVLPEHRGKGYVGSLLAEITRCHAETGATTITADTDTVNIPMAKAFERAGYANFANRLVLGEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3N1</accession>
    <name>D3Q3N1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4301"/>
    <dbReference type="EnsemblBacteria" id="ADD43948">
        <property type="protein sequence ID" value="ADD43948"/>
        <property type="gene ID" value="Snas_4301"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4301"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_1_5_11"/>
    <dbReference type="OMA" id="RYAMEIV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="28"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="25011" checksum="28C7F4E2B2DCC389" modified="2010-04-20" version="1">MINCYGCRMAEPAPRRTPETSERQRDAERSKRRLLEAAFDEFAAHGFAGARVGRIAEAAGVNKQLISYYFGCKEGLYQAMQRSWLDAEAVNANPAVPAADTMMWYLRESLSDPRGVRLLLWQALNDDAPDVQDQADYEREQEWMRRRVESGEFAADLDPEALQLVFMGMTMMPAAMPHLVRQLFGVEPNSEEFIERYGKTLRRVLAALADPPKPPKKGSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3N6</accession>
    <name>D3Q3N6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chitinase</fullName>
            <ecNumber evidence="7">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4306</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.14" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019524.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4306"/>
    <dbReference type="CAZy" id="CBM5">
        <property type="family name" value="Carbohydrate-Binding Module Family 5"/>
    </dbReference>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43953">
        <property type="protein sequence ID" value="ADD43953"/>
        <property type="gene ID" value="Snas_4306"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4306"/>
    <dbReference type="eggNOG" id="COG3325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002833_13_0_11"/>
    <dbReference type="OMA" id="WAGNPSH"/>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009470">
        <property type="entry name" value="Chi_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02839">
        <property type="entry name" value="CBM_5_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06483">
        <property type="entry name" value="ChiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="SSF54556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049678" evidence="5">
        <location>
            <begin position="32"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="6">
        <location>
            <begin position="67"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="693"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="701"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="772" mass="83873" checksum="6AB8BE96B2B5D702" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3T3</accession>
    <name>D3Q3T3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019571.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4353"/>
    <dbReference type="EnsemblBacteria" id="ADD44000">
        <property type="protein sequence ID" value="ADD44000"/>
        <property type="gene ID" value="Snas_4353"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4353"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108054_2_1_11"/>
    <dbReference type="OMA" id="TKPAHQP"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="118" mass="12607" checksum="0879F915AE0EB413" modified="2010-04-20" version="1">MSTTKLSAFVIDCADPVMLAEFYRAATGWDITHSDADSAQLSDGGTVGLGFQRIAGYQGPGWPDDAKQYHLDLSSADVDATVDRLLAIGARKPDFQPGGEDWTVLADPEGHLFCVCAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3U3</accession>
    <name>D3Q3U3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019581.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4363"/>
    <dbReference type="EnsemblBacteria" id="ADD44010">
        <property type="protein sequence ID" value="ADD44010"/>
        <property type="gene ID" value="Snas_4363"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4363"/>
    <dbReference type="eggNOG" id="ENOG5031Y0Q">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1634361_0_0_11"/>
    <dbReference type="OMA" id="VAVWAWR"/>
    <dbReference type="OrthoDB" id="1775349at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019692">
        <property type="entry name" value="DUF2581"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10756">
        <property type="entry name" value="bPH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="162" mass="17488" checksum="C8B705D8EC7EEC5C" modified="2010-04-20" version="1">MTVINAKPTRLRFRRSGAVWIGAVVMLVFVFPFSGSVFAELDGMARILLAPVAVVAVLVPLLIALWSLRSGVDITAEGLTVKALVGSRSYRWSAIDGFDLRGRTVYALLTDERRVPLPAVRATDIPRLIVASGGELVETDDADEPDDEAEPPAEAVSRDEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3U7</accession>
    <name>D3Q3U7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acylglycerol lipase</fullName>
            <ecNumber evidence="2">3.1.1.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.23" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019585.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4367"/>
    <dbReference type="ESTHER" id="stanl-d3q3u7">
        <property type="family name" value="Monoglyceridelipase_lysophospholip"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44014">
        <property type="protein sequence ID" value="ADD44014"/>
        <property type="gene ID" value="Snas_4367"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4367"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026209_7_2_11"/>
    <dbReference type="OMA" id="KPRWPIP"/>
    <dbReference type="OrthoDB" id="1694750at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:acylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="23"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="265" mass="29154" checksum="69B7F4C7947784C8" modified="2010-04-20" version="1">MTTEWEFDGSTGKITARTWPVEAPRYLAVLVHGYGEHIGRYEYVAATLNRHGATVYGLDHMGHGKSEGERVLIDDYEAVVADVHHVVQRARADRPGLPLVLIGHSMGGMIAARYAQHHGAELAALVLSGPVIGSWEQVTSMLEMPEIPFVPINVATLSRDPEIGRIYAEDPLVWHGPFKRELIAALDRCLKAINAGPKLGSLPTLWVHGAADELVPLEPSRAGVETIRGENFTERVYGEARHEVFNETNKDEVLGDVTAFIDRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4F1</accession>
    <name>D3Q4F1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015682.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0394"/>
    <dbReference type="EnsemblBacteria" id="ADD40111">
        <property type="protein sequence ID" value="ADD40111"/>
        <property type="gene ID" value="Snas_0394"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0394"/>
    <dbReference type="HOGENOM" id="CLU_741680_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="373" mass="37329" checksum="759B0213EC7BB5F9" modified="2010-04-20" version="1">MPSFEQLEMYFSQIDAASPAASAQANWIAGAAEARQLAAELRKNVDELLQYWSGPAATEYNGAMNAIIEFADGLADDMTDMSTGLASMASTAASIQPQGLAIINAARSNPYSRAAAIAPLTALLTALGQAYQSNKGQYWREPKEAPQKLPKPGGEGDSTPTQTDVPPDVRPAPILGDLEDIGQFLQLASSTYEAFKEDDFPSGVTGEFPVNPGPGYPGGGGGDGGGSYPGPGGGPLPGPDHPDYQPLPEPDTELTESPVSLAGATPTGLAGGTPAVSLGAGGGSAMGAPGGAMPMAMGMGAAGAAGSAARPAASARGAGGAGGGLFAPPMGAARRNDSDEAPEGVRTWLTEDELAWDAEPAPTGVVGHPRAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4J0</accession>
    <name>D3Q4J0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0435"/>
    <dbReference type="EnsemblBacteria" id="ADD40150">
        <property type="protein sequence ID" value="ADD40150"/>
        <property type="gene ID" value="Snas_0435"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0435"/>
    <dbReference type="eggNOG" id="ENOG5031DPD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_771406_0_0_11"/>
    <dbReference type="OMA" id="RNGRSIW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="359" mass="40201" checksum="76F525BF636C6D13" modified="2010-04-20" version="1">MTKTTVRQLAERMAELGMITRDAAEAALAHIGRWRLEALDEIVDADELIDYLPEFGVAISVHGEDVDHVEDYYQSILESDVTACTGGAVTVTDVTLVRVGEDTEWLYFLRNGEPVWWYVEHQSDDYVDQLSVSEQFEDLYPGGDDPRGFLLVHRSKAEACQDDVYVLATIEQATALRDEFGIDFLVLHRRQLPVQDTREAGDFLEHWTSNMDELLHSWRSRFLPPGFPFDFSVASLDTLERLVLNRFADWDAVQRAAADPFVVGAVGYLGETLLRAAPGSWDYWTGASVYDRTPLLRSNTPKAFGTTVVPLVLLSRVAGDRDFGILAEAVEDLLRAEASYAEALRALDTAPAAEDDEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4U8</accession>
    <name>D3Q4U8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FeS assembly ATPase SufC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2445</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Ycf16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017699.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2445"/>
    <dbReference type="EnsemblBacteria" id="ADD42128">
        <property type="protein sequence ID" value="ADD42128"/>
        <property type="gene ID" value="Snas_2445"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2445"/>
    <dbReference type="eggNOG" id="COG0396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_48_1_11"/>
    <dbReference type="OMA" id="MAMLEPK"/>
    <dbReference type="OrthoDB" id="1214676at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01978">
        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="259" mass="27899" checksum="7F780377A7DC839F" modified="2010-04-20" version="1">MSTLSIRDLHVSVNTGEGEVKEILKGVDLTINSGETHAIMGPNGSGKSTLAYSIAGHPKYDITGGSVTLDGEDVLAMSVDERARAGLFLAMQYPVEVPGVSVSNFLRTAKTALDGEAPKLRTWMKDLKGAMSDLQMDDSFAQRNVNEGFSGGEKKRHEIMQLELLKPKMAILDETDSGLDIDALRVVSEGVNRAKAETGSGVLLITHYTRILRYIKPDFVHVFVGGRIVEEGGPELSERLESEGYERYVAGAGAATVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4X8</accession>
    <name>D3Q4X8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VanZ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2475"/>
    <dbReference type="EnsemblBacteria" id="ADD42158">
        <property type="protein sequence ID" value="ADD42158"/>
        <property type="gene ID" value="Snas_2475"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2475"/>
    <dbReference type="eggNOG" id="COG4767">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090667_0_0_11"/>
    <dbReference type="OMA" id="WWARRIV"/>
    <dbReference type="OrthoDB" id="1262421at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006976">
        <property type="entry name" value="VanZ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04892">
        <property type="entry name" value="VanZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="VanZ" evidence="2">
        <location>
            <begin position="66"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="186" mass="19774" checksum="D16228461AD66C3F" modified="2010-04-20" version="1">MTEVWDRWGTVLTATAVAVPVVVALVWALARRRIRDGADARTAWRRSAAEVCAVAGTLPWLWMVLTPRPAASTVNLVPLSDLAALFTAAPTTIVVQLGGNLLVFAALGFCLPIRFAIPVAAVALVGAAGATAIEVLQYLFDIGRVSSVDDVLVNTLGAVLAALLSRPWWVARTWAARTQPRRIPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q548</accession>
    <name>D3Q548_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sec-independent protein translocase protein TatC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tatC</name>
        <name evidence="7" type="ordered locus">Snas_4452</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TatC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019668.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4452"/>
    <dbReference type="EnsemblBacteria" id="ADD44097">
        <property type="protein sequence ID" value="ADD44097"/>
        <property type="gene ID" value="Snas_4452"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4452"/>
    <dbReference type="eggNOG" id="COG0805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031942_6_0_11"/>
    <dbReference type="OMA" id="EMSFLDH"/>
    <dbReference type="OrthoDB" id="1848013at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019820">
        <property type="entry name" value="Sec-indep_translocase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002033">
        <property type="entry name" value="TatC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30371">
        <property type="entry name" value="PTHR30371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01840">
        <property type="entry name" value="TATCFAMILY"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00945">
        <property type="entry name" value="tatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01218">
        <property type="entry name" value="TATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="330" mass="36923" checksum="25C428EBF3A42FAF" modified="2010-04-20" version="1">MALSLRRNKKPKKTKFQAAADGSMSLMDHLRDLRSRLFKACLGLVAGVLVGMYFADIIQEFINAPYCDWDKQNWLDKGHSAASYDGCNFNVVGPLDNFLLRLKIGLFAGIILSAPIWLYHLWAFIAPGLHKHERKYTYYFAAMAGPLFFAGATLGWFVISKSLQFFLALSNQYKLTVDLTGYFDFVTNVMLLFGAGFEFPLVVVLLNVIGIASAKRLLGWWRIATFLVFLFCAIVTPTPDPFGMIALAIPMVMLYFAAVGFAFINDRRRNRKTADWDTLDPDEASVIDDGPSDIGEVESVDDSDDLVDEIAESDGGSDNRPVRRYDEDAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q575</accession>
    <name>D3Q575_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4479</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4479"/>
    <dbReference type="EnsemblBacteria" id="ADD44124">
        <property type="protein sequence ID" value="ADD44124"/>
        <property type="gene ID" value="Snas_4479"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4479"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="LDKYATH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="8"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="153"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="224" mass="24164" checksum="E0BEFE8BAF2C8B00" modified="2010-04-20" version="1">MSTDKPIKVLLVDDQPLLRTGFRMVLGAEADIDIIAEAGDGVEAVDLARRLLPDVVLMDIRMPRMDGVAATKAIVEAKLPVRVLILTTFDLDEYVVGALRAGAAGFLAKDVPAEDLVAAIRSVSSGEAVVAPRILRRLLEKFVDRLPEPDGATPASLEVLTEREREVLILVAKGMSNTEIAKELTVSETTVKTHVGHVLTKLGVRDRVQAVVLAYETGLVKPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q599</accession>
    <name>D3Q599_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Undecaprenyl-diphosphatase</fullName>
            <ecNumber evidence="4 14">3.6.1.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Bacitracin resistance protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Undecaprenyl pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uppP</name>
        <name evidence="15" type="ordered locus">Snas_4503</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28094"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="EC" id="3.6.1.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the UppP family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.27" evidence="4 14"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019719.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4503"/>
    <dbReference type="EnsemblBacteria" id="ADD44148">
        <property type="protein sequence ID" value="ADD44148"/>
        <property type="gene ID" value="Snas_4503"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4503"/>
    <dbReference type="eggNOG" id="COG1968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060296_1_0_11"/>
    <dbReference type="OMA" id="PIMMGAS"/>
    <dbReference type="OrthoDB" id="1826154at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050380">
        <property type="term" value="F:undecaprenyl-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01006">
        <property type="entry name" value="Undec_diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003824">
        <property type="entry name" value="UppP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30622">
        <property type="entry name" value="PTHR30622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02673">
        <property type="entry name" value="BacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00753">
        <property type="entry name" value="undec_PP_bacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="6 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD44148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="278" mass="29697" checksum="AC19E75A2371F9D2" modified="2010-04-20" version="1">MELWQAVVLGIVEGLTEFLPVSSTGHLTIAEGLMGLKVNDPAITAYSVVIQSGAIAAVLVYFFKDIVRITAAFFRGLFNARARQDFDYKFGWYIIAGSIPIVIVGVLGKDIIKGPLRSLWVVAIALILWSGVMWFAEYAATHQRSEKQLKLKDTVIIGLAQCVALIPGVSRSGATISAGLLRDLDRVTATRLSFFLGIPALVGGGIYEFDEVFKSDIGVAPIVVGTVVSFGVAYASVAWLLKFVAGHSIAVFVWYRIGLGVLIMILLGTGAISSTGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5B5</accession>
    <name>D3Q5B5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid adenylation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4519</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019735.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4519"/>
    <dbReference type="EnsemblBacteria" id="ADD44164">
        <property type="protein sequence ID" value="ADD44164"/>
        <property type="gene ID" value="Snas_4519"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4519"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3320">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_4_11"/>
    <dbReference type="OMA" id="VEWIVEA"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="Far_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1044"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="508"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="752"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="826"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1022"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="515"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="758"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="845"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="1078"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1478" mass="157305" checksum="C726E6A02FCC71FF" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5B8</accession>
    <name>D3Q5B8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019738.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4522"/>
    <dbReference type="EnsemblBacteria" id="ADD44167">
        <property type="protein sequence ID" value="ADD44167"/>
        <property type="gene ID" value="Snas_4522"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4522"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1011589_0_0_11"/>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="275" mass="29606" checksum="4B3E3E326D0AA659" modified="2010-04-20" version="1">MTDSSARHSGRHRRRDLQFDTLRPALAFVAFPAVLTRASRHSLSFVRSALAYRPELNGLRRSLAGVGGVALLSLSLMGATPASGHAESHSEEPPASASSSQSDSTEKREERQEDVIEAKPESNKADKKEAPKPVAGLSGAQMDNAVAIVRVGDKLDISEKGQAIAIATAMQESKLKVLASHAVPESAEYDNEGFGADMDSVGLFQQRPSMGWGSVEECMDVEYSSTIFYKRLKQVSGWDDMAVAEAAQSVQASAFPDAYAQWEDLAYDVVNEVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5F7</accession>
    <name>D3Q5F7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Prephenate dehydratase</fullName>
            <shortName evidence="10">PDT</shortName>
            <ecNumber evidence="3 10">4.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pheA</name>
        <name evidence="14" type="ordered locus">Snas_6401</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="3 10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021588.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6401"/>
    <dbReference type="EnsemblBacteria" id="ADD46017">
        <property type="protein sequence ID" value="ADD46017"/>
        <property type="gene ID" value="Snas_6401"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6401"/>
    <dbReference type="eggNOG" id="COG0077">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035008_0_0_11"/>
    <dbReference type="OMA" id="PLMIYRE"/>
    <dbReference type="OrthoDB" id="1280729at2"/>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018528">
        <property type="entry name" value="Preph_deHydtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00858">
        <property type="entry name" value="PREPHENATE_DEHYDR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8 10 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 10" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="12">
        <location>
            <begin position="4"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="13">
        <location>
            <begin position="194"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="site" description="Essential for prephenate dehydratase activity" evidence="9">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001500-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD46017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="305" mass="31988" checksum="B254ECB61AB4EDD6" modified="2010-04-20" version="1">MPSVIAYLGPQGTFTEAALLRLPGADEAERRPMRSVPEAMDEVRSGACDAALVPIENSIEGSVPVTLDSLVRDSPLVITAEVVLPVSFVLAGRADGAVATIASHPHALAQCREFLRSKHSGASTVDALSTAAAAELVAGGRADACVCARLAAERHGLDILADDIGDNPGAVTRFGLVSRPVAAVAPSGNDVTSLAVYIAHDEVGALLRVLTELEVRGVNLTRIESRPTGERLGRYAFFLDCTGHIADARMGEALMGLRRVCAEVRYLGSYPRDTGEAPIPAPPGLSDGDFDDASQWLERLRANGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5F8</accession>
    <name>D3Q5F8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021589.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6402"/>
    <dbReference type="EnsemblBacteria" id="ADD46018">
        <property type="protein sequence ID" value="ADD46018"/>
        <property type="gene ID" value="Snas_6402"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6402"/>
    <dbReference type="eggNOG" id="ENOG5033AIW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148470_0_0_11"/>
    <dbReference type="OMA" id="WCEGGLV"/>
    <dbReference type="OrthoDB" id="1400520at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD46018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="142" mass="16068" checksum="B3494403C154EBCC" modified="2010-04-20" version="1">MLEEQKEFAGFANPVNPTPEELRAWAFDPAAGPPQTAAQWDLLLADDPLMPTLVELAADPVCPKRTFALHCLYLYAADAVRTGFRAHPKRKVRKVMEQAEAAQDAWVDLWVQNTQALIRDPDLFDYHDWCQGGLARRPRRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q679</accession>
    <name>D3Q679_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">def</name>
        <name evidence="3" type="ordered locus">Snas_2574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017825.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2574"/>
    <dbReference type="EnsemblBacteria" id="ADD42254">
        <property type="protein sequence ID" value="ADD42254"/>
        <property type="gene ID" value="Snas_2574"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2574"/>
    <dbReference type="eggNOG" id="COG0242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061901_1_2_11"/>
    <dbReference type="OMA" id="NMHGEPV"/>
    <dbReference type="OrthoDB" id="1649129at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="183" mass="20575" checksum="92D3620B52502199" modified="2010-04-20" version="1">MSIVPIRLFGDPVLRTPADEVKTFDKEFRKLVRNLTDTMLDEGGAGLAAPQLGVGLRVFAFDVDDVIGHLANPVLEFPDEEEQDGPEGCLSIPGLYFDTVRRQNVIAKGYNEYGDPMQIVGTGLMARCLQHETDHLDGILFLDRLDPERRKAAMKEIRSAEWYNDDVKVKISPHDNKGVFFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6A0</accession>
    <name>D3Q6A0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">rRNA (Adenine-N(6)-)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2596</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017846.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2596"/>
    <dbReference type="EnsemblBacteria" id="ADD42275">
        <property type="protein sequence ID" value="ADD42275"/>
        <property type="gene ID" value="Snas_2596"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2596"/>
    <dbReference type="eggNOG" id="COG0030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041220_3_1_11"/>
    <dbReference type="OMA" id="RHEHGQN"/>
    <dbReference type="OrthoDB" id="2030110at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="6">
        <location>
            <begin position="26"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="278" mass="30799" checksum="9BFFB2959327E2CD" modified="2010-04-20" version="1">MARSSSPVRAPKRRRLSQNFLTEPRVAAAVVRLSGVTRADLVVEIGPGRGILTQAIARKAGRVLAYELDPVLAKRLAARYGDDPRVHCVHRDFLSTSPPREPFSIVANIPYARTSAIVEWCLKARELDAATLITQLEYARKRSGDYGRWSQVTVESWPRFEWRLLGRVDRYKFDPVPRVDSGILRLERRETALLPGSAMADYQRFVALGFTGVGGSLAASLRREFGDRAVRRAFARAEVHPAAVVAFVTPPQWIELFTQLCGLSVAVPRLGTTGPGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6B2</accession>
    <name>D3Q6B2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2608</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017858.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2608"/>
    <dbReference type="EnsemblBacteria" id="ADD42287">
        <property type="protein sequence ID" value="ADD42287"/>
        <property type="gene ID" value="Snas_2608"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2608"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_11_0_11"/>
    <dbReference type="OMA" id="TPDDMRG"/>
    <dbReference type="OrthoDB" id="460405at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="393"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="232"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="426" mass="44549" checksum="B32B212D28BDC502" modified="2010-04-20" version="1">MSQSTRPRGARKALSAIIVDTRPLRIPAFRRLWMSTIVTGFGSQLTAVAVPKQIFDITGSSGWVGLTGAVALVPLLIFGLWGGAIADAMDRRKLLLIGNAGIAVVSGLLWLQTFLGLDSVWLVLVLLACNQAFFGITMPTRNAVVARLVPAELLPSAAALNGSMFMFSAVFGPLAAGALMPVIGLSTLYGIDTITLLLTMIAVWRLPALPPLSGTFGRAGIRDVLDGFRYMAVKKVLLASFVVDIIAMVAGMPRALFPEMAERTFGDPPGGGLALGWLFAAIPIGSLVITLLSGWVSKVRRQGVAVTISIAVWGLAVAGFGLSGNLWLAAMFLVIGGAADMVSSIYRQAILQTAATDEMRGRMQGAFTVVVAGGPRIADLTHGWAAAGAGTAVAATGGGILVVICVFAAVALLPSFWRYRAPSDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6C0</accession>
    <name>D3Q6C0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017866.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2617"/>
    <dbReference type="EnsemblBacteria" id="ADD42295">
        <property type="protein sequence ID" value="ADD42295"/>
        <property type="gene ID" value="Snas_2617"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2617"/>
    <dbReference type="HOGENOM" id="CLU_1554339_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="172" mass="19113" checksum="84B1B43916C44743" modified="2010-04-20" version="1">MSLLSGDKFASGSSGGSNLPKQVRISRVLLWVQAAIGLLLSAFILLGTYQQSQLSNTELAKLLKERLTAKVYNKQFKDDPPTQDLFNYPLLYLLAALLVVLMIVLIYCALKLKFRQKPVRLVTVIAEGLLIPFSLWELSTIGCALILPAMAVIVMLLSRQTKEWYDTAQPEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6T4</accession>
    <name>D3Q6T4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0619</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0619"/>
    <dbReference type="EnsemblBacteria" id="ADD40333">
        <property type="protein sequence ID" value="ADD40333"/>
        <property type="gene ID" value="Snas_0619"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0619"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="VNPRMTA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="9"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="332" mass="36051" checksum="8CB7B34FDADAEF64" modified="2010-04-20" version="1">MEPAAPPLLQLSGLEQVFDTKRGKVPAVSGVDLTVGKGKVVCLVGESGCGKTTTARAAAGLTRPTGGQVLYRGKDVARMAKQEWNTYREDVQYIHQDPYASLNPVRTILSSVTGGLKARGIVKTKKQAREAAIELLTRVDLTPPEYCLDKYPHQLSGGQRQRVSVARALAMEPKLLIADESTSMLDVSIRVSLLNTLGALRDDLGVGFLFITHDLAVAKYFAWDGEIAVMYLGKIVEQGPTPQIIGDPQHPYTKALISAVCEPDPKLARAKKTIRLRSSEIPSLTDLPSGCAFHPRCPLYEPGLCDNELPILESIDSRRLSCHVLARDLKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6U1</accession>
    <name>D3Q6U1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase</fullName>
            <ecNumber evidence="2">2.5.1.145</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lgt</name>
        <name evidence="4" type="ordered locus">Snas_0626</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:56712"/>
            <dbReference type="Rhea" id="RHEA-COMP:14679"/>
            <dbReference type="Rhea" id="RHEA-COMP:14680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="ChEBI" id="CHEBI:140658"/>
            <dbReference type="EC" id="2.5.1.145"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Lgt family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.145" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015911.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0626"/>
    <dbReference type="EnsemblBacteria" id="ADD40340">
        <property type="protein sequence ID" value="ADD40340"/>
        <property type="gene ID" value="Snas_0626"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0626"/>
    <dbReference type="eggNOG" id="COG0682">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013386_2_0_11"/>
    <dbReference type="OMA" id="HQYLFFI"/>
    <dbReference type="OrthoDB" id="435911at2"/>
    <dbReference type="UniPathway" id="UPA00664"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01147">
        <property type="entry name" value="Lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00544">
        <property type="entry name" value="lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)</name>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="35307" checksum="2A18C7DF5E8D27B0" modified="2010-04-20" version="1">MDYAFIPSPAQSVWEIPLPFGLAVPIRAYALCIVAGIVAACWVVEALLRRRGAPRFFVLDLAVWAVPFGIVGGRLYHVVTSPDAYFGADGEPLKAFAVWEGGLGVPGAIVLGGVGVWIACRRGQVPFSMVADAAAIGLPLGQAVARPCNWFNQELYGLPTNAPWGVEIDAAHQRDIPPEFRGAEAYEPAFLYESLWNFGLAAVIWRLDKRFKFGAGRAFAIYVLGYGVGRFWIEGRRIDVAHDFLGLRVNEWLSLVMIVGAIVYLLRVKGKRGVLVPGEAGGLRMVDWDSADARAGKLVEVEVGSGTVESEVSDEGSAEPDESKASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q705</accession>
    <name>D3Q705_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0691"/>
    <dbReference type="EnsemblBacteria" id="ADD40404">
        <property type="protein sequence ID" value="ADD40404"/>
        <property type="gene ID" value="Snas_0691"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0691"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151185_3_2_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="97" mass="10737" checksum="9970321902D8BD99" modified="2010-04-20" version="1">MSNIRYDYNGIDQCAEIIDGFLKKMDSELDGIETALKPLEGEAWRGSVAQEVYFEKKTEWRSAALKIAEALMNLKVSLGVSKEGMQSADIRAAGMFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q720</accession>
    <name>D3Q720_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sec-independent translocation protein mttA/Hcf106</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_0706</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015990.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0706"/>
    <dbReference type="EnsemblBacteria" id="ADD40419">
        <property type="protein sequence ID" value="ADD40419"/>
        <property type="gene ID" value="Snas_0706"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0706"/>
    <dbReference type="eggNOG" id="COG1826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086034_2_1_11"/>
    <dbReference type="OMA" id="RPAQRYD"/>
    <dbReference type="OrthoDB" id="2073616at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="90"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="118"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="146" mass="15973" checksum="B3E3E44D642F398B" modified="2010-04-20" version="1">MLDNLGGLEIVVLLLVALFIIGPERLPKVLKSVGNGIRKLRRMASNATADISKEVGHDIDITDLHPKTFIRKHVLSAADEEALKNPLKSALDDVKKHTQPLRDELDDTASAIRSKPGRANGSRRDRDDEDESPSSSKAHSYDADAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q726</accession>
    <name>D3Q726_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMMECR1 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015996.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0712"/>
    <dbReference type="EnsemblBacteria" id="ADD40425">
        <property type="protein sequence ID" value="ADD40425"/>
        <property type="gene ID" value="Snas_0712"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0712"/>
    <dbReference type="eggNOG" id="COG2078">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095686_0_0_11"/>
    <dbReference type="OMA" id="RGCIGFP"/>
    <dbReference type="OrthoDB" id="1812209at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023473">
        <property type="entry name" value="AMMECR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036071">
        <property type="entry name" value="AMMECR1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002733">
        <property type="entry name" value="AMMECR1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027485">
        <property type="entry name" value="AMMECR1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027623">
        <property type="entry name" value="AmmeMemoSam_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016">
        <property type="entry name" value="PTHR13016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01871">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143447">
        <property type="entry name" value="SSF143447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04335">
        <property type="entry name" value="AmmeMemoSam_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51112">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMMECR1" evidence="1">
        <location>
            <begin position="14"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="202" mass="21948" checksum="580A6E06A3C20DDB" modified="2010-04-20" version="1">MTEDSAFAAAVPTVAAEAVRHALLGENLDTDALLARLTGTDEPLAEALRREGASFVTLQRDGKLRGCIGTLIAHRRLLDDVAHNARKAMNDPRMPAVDRREWPQLSISVSVLSPPTPLPITDRADLEAALRPGVDGLTLREGGRRATFLPSVWESLPKPADFVAALLRKGGWDSDWPQAMTAETYGTDYYTSAPPRPPLEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7D4</accession>
    <name>D3Q7D4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017976.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2729"/>
    <dbReference type="EnsemblBacteria" id="ADD42405">
        <property type="protein sequence ID" value="ADD42405"/>
        <property type="gene ID" value="Snas_2729"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2729"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_11"/>
    <dbReference type="OMA" id="NWRGQFA"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="250" mass="25208" checksum="B2A82C30E3C36187" modified="2010-04-20" version="1">MSELDGKRAIVTGAGSGIGRATAELMAEQGARVAVVDLDADAAREVAEGIGAQAIAIATDVSKAADCDNAVATAAAEFGGLDVLVNNAGIIRRSTVCEITEEDWDLVMAVNIKSVMLMSRRAIPHLKAAGGGSIVNTGSGWGIQGGGQAVSYCASKGAVVNMTRAMAIDHGPDNIRVNCVCPGDTATPMLAEEARQLGEAPGAFYADAADRPLRRIGQPRDIASAIAYLAGDGAAFVSGAVLPVDGAGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7E1</accession>
    <name>D3Q7E1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Beta-galactosidase</fullName>
            <shortName evidence="5">Beta-gal</shortName>
            <ecNumber evidence="3 5">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Snas_2736</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 42 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3 5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017983.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2736"/>
    <dbReference type="CAZy" id="GH42">
        <property type="family name" value="Glycoside Hydrolase Family 42"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42412">
        <property type="protein sequence ID" value="ADD42412"/>
        <property type="gene ID" value="Snas_2736"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2736"/>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012430_1_1_11"/>
    <dbReference type="OMA" id="ANDHYLD"/>
    <dbReference type="OrthoDB" id="831762at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013739">
        <property type="entry name" value="Beta_galactosidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013738">
        <property type="entry name" value="Beta_galactosidase_Trimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003476">
        <property type="entry name" value="Glyco_hydro_42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013529">
        <property type="entry name" value="Glyco_hydro_42_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36447">
        <property type="entry name" value="PTHR36447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02449">
        <property type="entry name" value="Glyco_hydro_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08533">
        <property type="entry name" value="Glyco_hydro_42C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08532">
        <property type="entry name" value="Glyco_hydro_42M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001084">
        <property type="entry name" value="B-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Glyco_hydro_42" evidence="9">
        <location>
            <begin position="14"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_42M" evidence="10">
        <location>
            <begin position="394"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_42C" evidence="11">
        <location>
            <begin position="601"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001084-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001084-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001084-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD42412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="657" mass="73026" checksum="2CC6AB164964F89D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7E3</accession>
    <name>D3Q7E3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent pyridine nucleotide-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017985.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2738"/>
    <dbReference type="EnsemblBacteria" id="ADD42414">
        <property type="protein sequence ID" value="ADD42414"/>
        <property type="gene ID" value="Snas_2738"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2738"/>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003291_4_0_11"/>
    <dbReference type="OMA" id="PWHKAAF"/>
    <dbReference type="OrthoDB" id="1149616at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028202">
        <property type="entry name" value="Reductase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14759">
        <property type="entry name" value="Reductase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="4"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Reductase_C" evidence="2">
        <location>
            <begin position="318"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="385" mass="41221" checksum="65989335F322A3B6" modified="2010-04-20" version="1">MGRRIVVVGASAAGLTAADTLRREGHDGPIIVVGDETCPPYDRPPLSKQILAGTWQPEKITLRDEAALRRSEITLRLGTTATGLDTGARTVKLRDGETLGYDGLIIATGVAPRRLPIGVGMAGVHVMRTLDDALRLRDAITESTRLVVIGAGFLGAEVAASARTRGADVTVVDPLPVPMLRQFGERIGQRVAQMHRAHGVGLRLNTAVTGLRGDDAVTGVELDDGSVLDADVVLIAVGSTPNTGWLADSGLHVDDGVVCDSMCQASPDVYAAGDVARWFNPRFGLSMRVEHRMNATEQGMAAARNLLGQEKAFDPIPYFWTDQFDVKIQAYGHFPTDSEVAIVHGDLAEDKFVARYLTDGVITGVLGWNMPKQVRLERACVGDKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Q4</accession>
    <name>D3Q7Q4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4754</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019967.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44396">
        <property type="protein sequence ID" value="ADD44396"/>
        <property type="gene ID" value="Snas_4754"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4754"/>
    <dbReference type="eggNOG" id="ENOG5030TWB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_863080_0_0_11"/>
    <dbReference type="OMA" id="SHTADIY"/>
    <dbReference type="OrthoDB" id="1040548at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="322" mass="35344" checksum="039173F69899125E" modified="2010-04-20" version="1">MPLYMAGRFTPHDHTDDQRIWWSRTYDGNNWNGMNEVPGANSKAGPWLAVFNDQLYMVYGGVFASGTTDRSIWWTRFDGNTWAPVANVLDPEMRFNQTANRPCLIAKGDRLHLYWAGHLDNYGQPDPKIYHAIHDGQKWENAGALFSGLPYGVNGIYMSNSHTADIYLLTRDGDSIIMAWSSDGFNFDLDNRVVLPHQCLGLPSLVGFPSFGTAKLMVTFVKPGGGGLFGSVSTDHGHSWGPEFVVTNQPGNRPNYGTWGSADPFAVWVGGGYRVYAGRPQAGSTWQDPATGNALAPDQQPVYQLSSAATPSLAAYGDILFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q899</accession>
    <name>D3Q899_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018044.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2797"/>
    <dbReference type="EnsemblBacteria" id="ADD42473">
        <property type="protein sequence ID" value="ADD42473"/>
        <property type="gene ID" value="Snas_2797"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2797"/>
    <dbReference type="eggNOG" id="COG1158">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2178287_0_0_11"/>
    <dbReference type="OMA" id="QWSAKRE"/>
    <dbReference type="OrthoDB" id="1882650at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="111" mass="12561" checksum="315FF41B8928B3A7" modified="2010-04-20" version="1">MPQQQWSAKRERQYEKIKSSQKKRGASEDRAEEIAARTVNKNRAQSGEAKKSSKLSREDVSPQHRGGKRSGNRQGPGGPTLDQLYQEARRKNIRGRSTMNKAQLQRAVGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8E3</accession>
    <name>D3Q8E3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2842</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018088.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2842"/>
    <dbReference type="EnsemblBacteria" id="ADD42517">
        <property type="protein sequence ID" value="ADD42517"/>
        <property type="gene ID" value="Snas_2842"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2842"/>
    <dbReference type="eggNOG" id="COG0365">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_10_11"/>
    <dbReference type="OMA" id="HAWSNLF"/>
    <dbReference type="OrthoDB" id="326708at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="52"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="456"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="566" mass="61893" checksum="0551AEE6AE71023A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8L9</accession>
    <name>D3Q8L9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4820"/>
    <dbReference type="EnsemblBacteria" id="ADD44461">
        <property type="protein sequence ID" value="ADD44461"/>
        <property type="gene ID" value="Snas_4820"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4820"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033540_1_0_11"/>
    <dbReference type="OMA" id="ERRAHHY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="399" mass="43359" checksum="5F5916EA705914E5" modified="2010-04-20" version="1">MSQQVFADAIGKSKSWVDKVERGVRTLDKYSVLNEIADALAIDAQLLLGRDTPRRDDRYNCIDQLEVNSIRASLERYERLGRYLGAAALEPVSVSELRKSVKHAWFAFEGANYPVLARTLIELLKSAPIAEEHAPEHEKAEAAGLLTQVYQIASSVLRKLGEAQLSWLAADRAIGAAQRCDDPLLIGIATMRVGNALRSLGRHQAALDLNVQVAHGLMTEIGSAARAQPEALSVYGILLLQGAMAASLSGDTATTRDLLNSAGRAASRVGPGVNHYWTSFGPMNVELHRAASAVELGDGRLALQIHERLDRAELEGLVPERRAHHYLDLARGCAQIGEFDKAGRALVAADRNAPSEIRCRPIAHEVISDVLRRTRGSAPLPVRQLADRMGIAALCRSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9E8</accession>
    <name>D3Q9E8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acid phosphatase (Class B)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018201.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2955"/>
    <dbReference type="EnsemblBacteria" id="ADD42630">
        <property type="protein sequence ID" value="ADD42630"/>
        <property type="gene ID" value="Snas_2955"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2955"/>
    <dbReference type="eggNOG" id="COG2503">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105429_0_0_11"/>
    <dbReference type="OMA" id="DYDGQLS"/>
    <dbReference type="OrthoDB" id="1535353at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005519">
        <property type="entry name" value="Acid_phosphat_B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03767">
        <property type="entry name" value="Acid_phosphat_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049664" evidence="2">
        <location>
            <begin position="18"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="181" mass="20185" checksum="A3EC8384A240CBE8" modified="2010-04-20" version="1">MLKRTLWTLSLALLVTAACTPVSPPDEERSSYDAWQDDVKAALKGIDSYLDEHDSENAAIVLDIDNTALETEYHPGKANPPVLKAEKYARKLGMTVLIVTARKEHAKEKSLAELRAAGYSPDDICLREFEESKSKGKARCRKEFTEAGHEITANIGNRDTDFKGGYYDRAFQLPDYDGQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9M8</accession>
    <name>D3Q9M8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cystathionine gamma-synthase</fullName>
            <ecNumber evidence="4">2.5.1.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4933</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.48" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020145.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4933"/>
    <dbReference type="EnsemblBacteria" id="ADD44574">
        <property type="protein sequence ID" value="ADD44574"/>
        <property type="gene ID" value="Snas_4933"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4933"/>
    <dbReference type="eggNOG" id="COG0626">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_2_0_11"/>
    <dbReference type="OMA" id="TTHSQMN"/>
    <dbReference type="OrthoDB" id="637281at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102028">
        <property type="term" value="F:cystathionine gamma-synthase activity (acts on O-phosphohomoserine)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="398" mass="42331" checksum="9DD238B9F65C19C9" modified="2010-04-20" version="1">MSHHDEFQIETTAVHAGERRPGPEGSVVFPIYQGTVYSVDEGTDYHDIKYLRLNSTPSQVYLHDKLAILEGSEAALATASGMAAITAALHSVLRAGDHLLIGDTLYGGTHDFITHHAADNGWSYTFVDPHRPDTWEPAKQPNTKAFYVESITNPLMRVGRLGEVADFTTEHGLVSIIDNTFATPVNFQPIKAGFDLSIHSATKYLNGHSDLVAGAVMGSADRVNAVRKTLNHYGGSLDAHAGFLLARGLKTLALRVKAQNANALALASALEAHPKVDVVNYPGLESHPDHEIARALFTGSGGTGDVRHSGFGGMLSIRPAGGLEAAKSLCELVQLPYSAPSLGGVESLITRPAVTSHGGMTAEARAAVGVTDDLVRISCGIEAVDDLVIDFMRALDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9N9</accession>
    <name>D3Q9N9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Flavin-containing monooxygenase FMO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4944</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020156.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4944"/>
    <dbReference type="EnsemblBacteria" id="ADD44585">
        <property type="protein sequence ID" value="ADD44585"/>
        <property type="gene ID" value="Snas_4944"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4944"/>
    <dbReference type="eggNOG" id="COG2072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006909_8_3_11"/>
    <dbReference type="OMA" id="DCYERET"/>
    <dbReference type="OrthoDB" id="324612at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="455" mass="51104" checksum="687BF0F30436E363" modified="2010-04-20" version="1">MSEYGVDAAYDRGDAVCVIGAGMAGLVAVKNLREHGFNVDCYEQETEIGGSWNIKKRRSPTYANTHLVSSRTQTEFPDFPMPDDWPDYPHHSKVLSYLESYADHFGLREHIWFGSEIERIENAERGRFDVVVKPMSGSAARRLRYAAVVIANGHNWDPFLPEYPGQQAYRGEIIHSVSYQDSSQLRGKKVLIVGAGNSGCDIAGESAITAKRTWQSTRRGYWYTPKYMLGLPADKTAQRLSWLPKGLRRKVTEYAIKKIGGDPVRFGLPAPDHRFGQSHPIVNSHILHHIGHGALEPKPDIARFDGRKVVFTDESTIEPDLVVMATGYRPRYDFCDDELLGAGRETGGFPRLFAQMFSPASETLFVAGLLQADVGIFPLVHWQTVAIAKWLHVRVSDPERAKAFRGQVVTEAGNRYVDAEMNDSDRHRLEVSHDRYLDSVARIIETLDKESDGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9P4</accession>
    <name>D3Q9P4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_4949</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020161.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4949"/>
    <dbReference type="EnsemblBacteria" id="ADD44590">
        <property type="protein sequence ID" value="ADD44590"/>
        <property type="gene ID" value="Snas_4949"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4949"/>
    <dbReference type="eggNOG" id="ENOG5030J67">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120964_2_1_11"/>
    <dbReference type="OMA" id="LIGMAFK"/>
    <dbReference type="OrthoDB" id="1841827at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023845">
        <property type="entry name" value="DUF3817_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12823">
        <property type="entry name" value="DUF3817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03954">
        <property type="entry name" value="integ_memb_HG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3817" evidence="8">
        <location>
            <begin position="6"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="107" mass="11786" checksum="769AAE66086E83BA" modified="2010-04-20" version="1">MPGPYRLFIAVAIAEAVSWVGLLIGMYFKHYGGGNEIGVKIFGPVHGVLFMGYVTFVLVLARQYSWSAKRVVAGLVCSIPPLASIGFERWVARDFRARKETRVPVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9T3</accession>
    <name>D3Q9T3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_4992</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4992"/>
    <dbReference type="EnsemblBacteria" id="ADD44629">
        <property type="protein sequence ID" value="ADD44629"/>
        <property type="gene ID" value="Snas_4992"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4992"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="ETWIISA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="479"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="20"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="510"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="532" mass="55790" checksum="D410D091B6A711F4" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAX1</accession>
    <name>D3QAX1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_5132</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020338.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5132"/>
    <dbReference type="EnsemblBacteria" id="ADD44767">
        <property type="protein sequence ID" value="ADD44767"/>
        <property type="gene ID" value="Snas_5132"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5132"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_0_0_11"/>
    <dbReference type="OMA" id="STWYLVP"/>
    <dbReference type="OrthoDB" id="1552415at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="358" mass="38037" checksum="29CB2407F7992D15" modified="2010-04-20" version="1">MRGFASLSKALFKGFVRDKVSVFFTIVFPLMFLVIFGALFSDSGSSSSTIIQVGKVEALDGMKQADPDAYEKLFDVTKSNDQDAAIAAVEQGDADAVVRQDGEDVYVYYSAADQTRAAIVQASISGVVDAGNLHKLTAAAPDVPVDAVKPEKVEDESLTTIQYLTPGLLGWAISISGVFGAAATLVDWRKNKILRRLRLAPVPIPSVIGARVGVSMVTSIVQMGIFVAVASIPFFGLQLTGYWWMAIPVLLVGTLAFLSIGMVVGAIAKTAEGASGLGNLIVMPMAFASGSFFPLDQSPVWLQTIAKISPLTYINEGLLSVMVRGNGPASVLAPMGMLLAFTVVFAALAWKLFKWDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAZ5</accession>
    <name>D3QAZ5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020362.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5156"/>
    <dbReference type="EnsemblBacteria" id="ADD44791">
        <property type="protein sequence ID" value="ADD44791"/>
        <property type="gene ID" value="Snas_5156"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5156"/>
    <dbReference type="eggNOG" id="COG1359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_189245_0_0_11"/>
    <dbReference type="OMA" id="LMWEARA"/>
    <dbReference type="OrthoDB" id="1850202at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="89" mass="10125" checksum="17A025752B27C83B" modified="2010-04-20" version="1">MIARMWEVRGLPERIDELVDWVCATAVPRIEDEPGYVRSEVYASEDRVVVISSWRDAAVDLPEAPPDLVARPPHAWDFNLIDRHSGTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB26</accession>
    <name>D3QB26_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1133</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1133"/>
    <dbReference type="EnsemblBacteria" id="ADD40843">
        <property type="protein sequence ID" value="ADD40843"/>
        <property type="gene ID" value="Snas_1133"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1133"/>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073856_0_0_11"/>
    <dbReference type="OMA" id="QIWMPST"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049842" evidence="3">
        <location>
            <begin position="21"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="128"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="22"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="358" mass="37533" checksum="D95D91A27FE1BEEA" modified="2010-04-20" version="1">MVGLCALVLSVFVAPAEAVAKEGNVNKKLDKAIDEYQEAKQDLAKSKGRKKTIKKDIADTKKDVKRLKVEVNEFAAAAYKSGGLPPAVEILSAGDPDTAVDTIAMTSYLGEQSGRKLSQLVNAKEDLAAEEESLDDEIDKGEKAEKKMKDLRDKAARDVAAGGGDAVTGPAASSAPPAEAAPRNSDGSWPDEGCTQDDPTTGGCISPRMEHALEQAVIVGYNKKTSCYRPYEDGGDHNEGKACDFTVGSNGAAASGDAKTYGDHTADWFVQNADALGVRVVIWYNMIWNPLRGGWHAYDGGGTGDPNSDHTNHVHVSILLAGLGRADGAAELLTAPAGFSRSPPWSSCAASPAGGTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBB1</accession>
    <name>D3QBB1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplQ</name>
        <name evidence="7" type="ordered locus">Snas_1218</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Contacts protein L32.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016499.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1218"/>
    <dbReference type="EnsemblBacteria" id="ADD40928">
        <property type="protein sequence ID" value="ADD40928"/>
        <property type="gene ID" value="Snas_1218"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1218"/>
    <dbReference type="eggNOG" id="COG0203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074407_0_0_11"/>
    <dbReference type="OMA" id="YAVTELF"/>
    <dbReference type="OrthoDB" id="1838961at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_L17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="PTHR14413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="SSF64263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="121"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="170" mass="18494" checksum="B0D800CE36139FF7" modified="2010-04-20" version="1">MPQPTKGARLGGSPAHQRLMLANLATSLFKHGKITTTEAKARKLRPYAERLVTFAKRGDLASRRRAIAKMTEKDVTHELFDSIASRYTNRDGGYTRIVKIGPRKGDNAPMAVIELVEELAEAPKPKRKPATRKAAKAEAVEALAGGDDEATDEPKAAEAKADDSKKSDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBZ8</accession>
    <name>D3QBZ8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5253"/>
    <dbReference type="EnsemblBacteria" id="ADD44887">
        <property type="protein sequence ID" value="ADD44887"/>
        <property type="gene ID" value="Snas_5253"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5253"/>
    <dbReference type="eggNOG" id="ENOG502Z9D4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076890_0_0_11"/>
    <dbReference type="OMA" id="ITHWSTI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="339" mass="35969" checksum="E0BACFD7CF718099" modified="2010-04-20" version="1">MSNETELVNAQLSLRPNLRVMSTWHKPLMVNVTLMTALVLVSTVGLFLDDRVLLNESIWLKPLKFGFAFAVYSATLAWLLTKLKKAKRFGWWFGLMFAVFGITDVAVIALAASQGTFSHFAEGDSMVNQIVQTVFQYGVPPLLISNLVIGILVLVQRTGDRALSWALRAGLLLSTAGMAVAFALIPASYAGERTVTDANGDKVAMSVGHGIGDPDGTGMPLTNWSSTGGDLRVPHFIGLHGIHVLLLTVLVLAVLAARVAWLRDDRVRAGLVGAVAIGYTGLFAVTTWQAARGQSLIHPDSSTLLAMAGAVLVAAAVALVTVAAGRRRAGSAKELVTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU79</accession>
    <name>D3PU79_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase subunit beta</fullName>
            <ecNumber evidence="11">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F1 sector subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-ATPase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpD</name>
        <name evidence="13" type="ordered locus">Snas_1316</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="11"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016596.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1316"/>
    <dbReference type="EnsemblBacteria" id="ADD41025">
        <property type="protein sequence ID" value="ADD41025"/>
        <property type="gene ID" value="Snas_1316"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1316"/>
    <dbReference type="eggNOG" id="COG0055">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022398_0_2_11"/>
    <dbReference type="OMA" id="GFNMIMD"/>
    <dbReference type="OrthoDB" id="430176at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0139">CF(1)</keyword>
    <keyword evidence="11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="12">
        <location>
            <begin position="153"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="161"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD41025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="477" mass="52529" checksum="7FAA08E6B4C2E719" modified="2010-04-20" version="1">MTQESTGTGRVVRVIGPVVDVEFPRNALPEIYYALKVDVELSEGTKTLTMEVAQHLGDNTVRAICMQPTDGLVRGTEVRDTGREIAVPVGDGVKGHVFNTIGECLNLEPGEEIEAEDYWTIHRKPPPFAALEPKTEMLETGIKVLDLLAPYVKGGKIGLFGGAGVGKTVLIQEMVIRVAQNFGGSSVFAGVGERTREGNDMIAEMKESGVLEQTALVYGQMDEPPGTRLRVALSALTMAEYFRDVKNQEVLLFVDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSLRGKAITSMQAIYVPADDYTDPAPHTAFTHLDATTNLERKVSDKGIYPAVDPLASSSRILEPEVVGDEHYRVAAEVKRILQKYNELQDIIAILGMDELSEEDKLVVGRARRIERFLSQNTYAAKQFTGVDGSFVPVKETVEAFKKIAEGEYDHFPEQAFFMCGGLEDLHKKEEELRKAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUL2</accession>
    <name>D3PUL2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3360</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018596.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3360"/>
    <dbReference type="EnsemblBacteria" id="ADD43025">
        <property type="protein sequence ID" value="ADD43025"/>
        <property type="gene ID" value="Snas_3360"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3360"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="LKYAHGS"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="3">
        <location>
            <begin position="184"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="384" mass="41652" checksum="F0426135C0D957D9" modified="2010-04-20" version="1">MIDLRRARDTWRGWDVTIRDLPLALLLFGGSFLPALRDHVTQVGDLPPRPFDAYAAVLLVVLCAPVAVRRRWPAVSLALVSLGFLIGELFSYHFVAGAALPIAILSAGAHLAHHRRVTIAILSTVYVALAITLDRFGSTEGFAGFGLFYLGLAISWGVGSWLRSTRATEAERRRLVAEATRTTERERIARELHDVVTHHVTAMVVQAEAARYLTATPDRLDETLTAVTDTGRRAITDLRHLLDLLNPDHGTETPTPSIGDLHSLVEHTRRAGQPVEFTETGTPNSHNGSAEFVAHRVVQEALTNALKHAHGQRTTVEVHYRSQEIAVEVTTDGSGSQAASPGGSGRGLTGLRERVSALGGDFSAVHHRPDGYLIRARIPTGTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUS7</accession>
    <name>D3PUS7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020522.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5317"/>
    <dbReference type="EnsemblBacteria" id="ADD44951">
        <property type="protein sequence ID" value="ADD44951"/>
        <property type="gene ID" value="Snas_5317"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5317"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_1_11"/>
    <dbReference type="OMA" id="FRYPRED"/>
    <dbReference type="OrthoDB" id="816674at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="395" mass="42663" checksum="2EF2C1E59BEFCF19" modified="2010-04-20" version="1">MTTAVDTPRLPFEQPDPLLLPPVLRRLREQGTVHKVRTATGDPAWLVTGYEQVKALAGDARLGRSHPDPDSAARLSDSAMFGGRPSGDFDTEPADHVQFRGLLTPFFTAKRMRALEPRVEALVEELLDDMERRPGSADLNAALAHPLPVLVICELLGVPYDDRDEFRAASEAAASTVDAEVSQRGMGELFTYMRELVALKRKQPADDVISGLCAIDGIDDDTVAGLAAALLFAGHVTTVTEIGYATVLLLSDPQQRRLLAEDPARVAGAVEECLRYRGSGSGGLFRYPREDIEVAGVRIGAGELVLLDLGAANHDPEVFDAPDRFDITRPGNAHLAFSHGGYYCIGAALARIELRAAIGALFRRFPGLRLAVPVESLEVRKEALDGGLVTVPVTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUX4</accession>
    <name>D3PUX4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5365"/>
    <dbReference type="EnsemblBacteria" id="ADD44998">
        <property type="protein sequence ID" value="ADD44998"/>
        <property type="gene ID" value="Snas_5365"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5365"/>
    <dbReference type="HOGENOM" id="CLU_1915811_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="132" mass="14218" checksum="EABEDC545ECBA266" modified="2010-04-20" version="1">MMASDVTIDVPEILALSKRLRAEAEAFDKAAESIRSEFDVGGIMSPSTQGDMPYGADARNQPASAVMAIHGLAVERARQLIDHSRDSMYRASRLTEAIAMSLRGQDESDAANLAVVTRMLNIPRSAEPGRDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVK0</accession>
    <name>D3PVK0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018685.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3450"/>
    <dbReference type="EnsemblBacteria" id="ADD43114">
        <property type="protein sequence ID" value="ADD43114"/>
        <property type="gene ID" value="Snas_3450"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3450"/>
    <dbReference type="HOGENOM" id="CLU_084215_2_1_11"/>
    <dbReference type="OMA" id="DAAHRHY"/>
    <dbReference type="OrthoDB" id="1923580at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039708">
        <property type="entry name" value="MT1774/Rv1733c-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42305">
        <property type="entry name" value="PTHR42305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="192" mass="21730" checksum="D6330FDDCC0D5AE8" modified="2010-04-20" version="1">MIRWRLVTDAARFARLLSLDDNPLRREVDRVEAMAARFVILIVAALLPVCVWLGMRIHEDGLATMESQALTHYQVTAVLTHDIQPAVATSSYQQRWGEARWQTRHGIEDSGRVKAPAGARAGDTVTIWLDGDDQLAEPPLTRQQASGRAVFAAVFAYIGVVELGFGVCWLVRRRLDRIRMRSWETQWSRFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVP7</accession>
    <name>D3PVP7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase domain protein TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018732.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3498"/>
    <dbReference type="EnsemblBacteria" id="ADD43161">
        <property type="protein sequence ID" value="ADD43161"/>
        <property type="gene ID" value="Snas_3498"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3498"/>
    <dbReference type="eggNOG" id="COG1082">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059523_1_2_11"/>
    <dbReference type="OMA" id="LWHVKDM"/>
    <dbReference type="OrthoDB" id="1194699at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="74"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="248" mass="27038" checksum="7423189C3835C82B" modified="2010-04-20" version="1">MDAHTHPPALQLYSIRDPFAQDPLRTLQRVAEIGYRQLELWGIVENLAPLRDGLRDTGLTAPTAHARITDSGHEEAFAAAKDLGVDTVIEPYVEPKRWEDAADIAATASRLNELAGIAADHGLRLGYHNHWWELKYRVGDRTAFEVFADQLDPAVILEVDTYWATVGGVDAAELLRRLGDRVHAIHVKDGGLAVDGSGQVPAGRGSVPVTEILAAAPTALRIVEFDHYDGDIFDAVAASFTYLTGAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVV3</accession>
    <name>D3PVV3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5442</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5442"/>
    <dbReference type="EnsemblBacteria" id="ADD45074">
        <property type="protein sequence ID" value="ADD45074"/>
        <property type="gene ID" value="Snas_5442"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5442"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_504223_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="464"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="506"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="21"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="540" mass="58131" checksum="E7FFDC0959D31B20" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVX6</accession>
    <name>D3PVX6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020668.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5466"/>
    <dbReference type="EnsemblBacteria" id="ADD45097">
        <property type="protein sequence ID" value="ADD45097"/>
        <property type="gene ID" value="Snas_5466"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5466"/>
    <dbReference type="eggNOG" id="COG0510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077925_0_0_11"/>
    <dbReference type="OMA" id="WYAREAA"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="93"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="324" mass="34891" checksum="AFDD863EDA6040E7" modified="2010-04-20" version="1">MRFELGDPVPYDATANRPGYDTLPAEVRADITAHLGSEPVHIAKAGGGFTGGFAGVLTGADESRIFVKAAGPHTPFVTNAYSAEAHISPRLPDGVPAPDLRFASQVGEWVVLGFEAIEGRAARLPLDPHDLDRMLAAWASAAEALTPAPQALVELGLPRFADVVGDTFQNFASIVAGELSAPDLQGFPDHFEELARLEAGFNDVLDVDAVHHGDLRPDNMILADDKVWICDWNNPVIGSPVLDTVAFLVVAHGDGHDAEALLKAHPSASGFDDEEIDVILAAIAGYYLCNGDKPLIENVSRYIRQHQRWNGLATLDWLARRRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW76</accession>
    <name>D3PW76_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc/iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1529</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016804.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1529"/>
    <dbReference type="EnsemblBacteria" id="ADD41233">
        <property type="protein sequence ID" value="ADD41233"/>
        <property type="gene ID" value="Snas_1529"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1529"/>
    <dbReference type="eggNOG" id="COG0428">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1085171_0_0_11"/>
    <dbReference type="OMA" id="IAHDFAD"/>
    <dbReference type="OrthoDB" id="1469769at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="243" mass="24914" checksum="1ECBF1DAED402CF3" modified="2010-04-20" version="1">MAIVLALAAFGSTLLGGLVALRARNAQNLVLGLAAGVMLGVVAFDLMPEALDQAPAELFGVPGPMLTAAGGFLTIHVIERSLAIHRGHEAEFGAHQHGLESVGLLAGSGLVVHSALDGVGIGLAFQVDASVGITVAVAVIAHDFADGFNTFTITTLYGNARKRALLLLFLDAVAPVAGALLASLFTVSPAAIGLYLGYFAGFLLYLATSDILPEAHAKRPSHLTLLCTVAGVAFMWLVVGLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWC3</accession>
    <name>D3PWC3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ThiJ/PfpI domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016851.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1577"/>
    <dbReference type="MEROPS" id="C56.004"/>
    <dbReference type="EnsemblBacteria" id="ADD41280">
        <property type="protein sequence ID" value="ADD41280"/>
        <property type="gene ID" value="Snas_1577"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1577"/>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070319_1_1_11"/>
    <dbReference type="OMA" id="YEKAAQP"/>
    <dbReference type="OrthoDB" id="1152952at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="25"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="235" mass="24735" checksum="55A2799C5BDF1A22" modified="2010-04-20" version="1">MTDSNAILMVLTGHSELGETGRVTGFHVAEAAYPWKAFTEAGYRVDFATSGTGTPTPDSADRSDPTQRDFLDDAGVLEQLADPKRPLDIDAAGYKAIFYVGGHGTMWDFPNDTALSGLARDIYEAGGVVAAICHGPAGLVNVKLSDGSYLVDGKSLTSFTDSEERAVKAMDIVPFALESTLVERGAHHTGMADFTANTVVDDRLVTGQNPASAPMTAAAVVEVLERLPGGTGNQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWN6</accession>
    <name>D3PWN6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD-40 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3598</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3598"/>
    <dbReference type="EnsemblBacteria" id="ADD43258">
        <property type="protein sequence ID" value="ADD43258"/>
        <property type="gene ID" value="Snas_3598"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3598"/>
    <dbReference type="eggNOG" id="COG2319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_364808_0_0_11"/>
    <dbReference type="OMA" id="DWTAPDN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="714"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="774" mass="84083" checksum="BF80C8C8ABB1AA7D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWS3</accession>
    <name>D3PWS3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3637</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3637"/>
    <dbReference type="EnsemblBacteria" id="ADD43295">
        <property type="protein sequence ID" value="ADD43295"/>
        <property type="gene ID" value="Snas_3637"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3637"/>
    <dbReference type="eggNOG" id="COG3620">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="757" mass="82562" checksum="B93663C6E0CFB719" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWZ4</accession>
    <name>D3PWZ4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_5588</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020789.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5588"/>
    <dbReference type="EnsemblBacteria" id="ADD45218">
        <property type="protein sequence ID" value="ADD45218"/>
        <property type="gene ID" value="Snas_5588"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5588"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_2_0_11"/>
    <dbReference type="OMA" id="WFAEYQP"/>
    <dbReference type="OrthoDB" id="1891092at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="9">
        <location>
            <begin position="11"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD45218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="261" mass="28132" checksum="745738918423CF84" modified="2010-04-20" version="1">MSTYVIRDSTAMLRRNIKKAIRYPSLTLMVIGMPIIFLVLFVYVFGSTLGDGLGGTSGGRDAYLTYVTPGILLFGILGSVQGTAITVSMDKTEGIMDRFRTMAISRSSVLTGHVIGSLIQTVLGTAVVMAVAVALGFRSDATPLEWLGVLGVMVMVSFAFIWMSVLVGLIAKTVESASNIPMPLMMLPFLGSGFVPTDTMPAGLRTFAEYQPFTPVNETLRGLLLGTEIGDSAWLAVAWCAGISLVCFLLARRRFNRPQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX01</accession>
    <name>D3PX01_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5595</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020796.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5595"/>
    <dbReference type="EnsemblBacteria" id="ADD45225">
        <property type="protein sequence ID" value="ADD45225"/>
        <property type="gene ID" value="Snas_5595"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5595"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_8_11"/>
    <dbReference type="OMA" id="AIIAHES"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="148"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="215" mass="22895" checksum="588DBC230257C327" modified="2010-04-20" version="1">MIRVLLADDENMVREGVKSILTTDAGIEVVAEAGNGREAVELARAHRPDVALIDIRMPVLDGLGALAELRQAAPATRCVMLTTFDEDEFIARALDAGAAGFLLKASDPRELIIGVRAVADGAAYLSPRVAGRVIAEFDTDRLTRGTGAQRKVAELTPRENEVLGLIASGLSNQEIGRRLHLTEGTVKAHVSAILQRLGVRNRVEAAIIGYQAGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX09</accession>
    <name>D3PX09_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular ligand-binding receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5603</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5603"/>
    <dbReference type="EnsemblBacteria" id="ADD45233">
        <property type="protein sequence ID" value="ADD45233"/>
        <property type="gene ID" value="Snas_5603"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5603"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_6_2_11"/>
    <dbReference type="OMA" id="DGWDSEK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005670595" evidence="1">
        <location>
            <begin position="32"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="49"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="393" mass="42031" checksum="80A9467DED5BEAF6" modified="2010-04-20" version="1">MRIRIASATAIVAATLLLTGCVESSTGNDKAEGNLVGKGEGAKCQIEDPVKVGAVFSLTEAAAFAGTYQKEGLELAFKELNKKDGVEYELIQEDDKTDVKASLAAFEKLIDREKVSAIVGPTLSNLAFKTYQDAEQAGVPALGVSTTAEGIPDIGDYIFRNSLPEQYALAASIPAAKDALDLKKVAVLHDEQDEFTASAYKTMKETLKEAEIDIVADEQFQTTDTEFRSQLTNVKSAKPDALVLSALPGATIPLVKQARELGIDAPIVGGNAFNSPVLIKQLEDAAEGLIVGGAWSAKTETPGNAEFIKAYKKAYDKDPDQFAAQAYTAGFLIDEAVRTDCDGNRDAIKDNLGQILKFDTVLGKLSLDETGEVHQEPVVQIVEDGKLTPLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX20</accession>
    <name>D3PX20_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020815.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5614"/>
    <dbReference type="EnsemblBacteria" id="ADD45244">
        <property type="protein sequence ID" value="ADD45244"/>
        <property type="gene ID" value="Snas_5614"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5614"/>
    <dbReference type="eggNOG" id="ENOG5032MIA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104649_0_0_11"/>
    <dbReference type="OMA" id="PWQRLLG"/>
    <dbReference type="OrthoDB" id="1663027at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="223" mass="23388" checksum="8F3C08B21D4AF189" modified="2010-04-20" version="1">MRFLRIAGLAGIGFTLVLIVANTFLLSSGFPAPSEAVAPERLAGIFDGSERTLRVASAFLPVAWLLSSIFAAGVFAVQSGRDVRRGDAWSVLGLAGVLLQNLAFTGVEATRLAMTAVESSDTLAGLWVLYNGFFGFNQVFLALALLGFSVSGLKGRMIARWHAAIGLAGAAALLASATTSPLATVNPLSLLGLIGWLLWVVWIAVYSVALLRGRLDPTRVAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXE5</accession>
    <name>D3PXE5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016979.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1709"/>
    <dbReference type="EnsemblBacteria" id="ADD41408">
        <property type="protein sequence ID" value="ADD41408"/>
        <property type="gene ID" value="Snas_1709"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1709"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_7_3_11"/>
    <dbReference type="OMA" id="IPWEYGY"/>
    <dbReference type="OrthoDB" id="1865374at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="46"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="22960" checksum="595FC9BBF1373B09" modified="2010-04-20" version="1">MSDRDKALRVWEKFAPRYDRTMRFFERWQFGGGREWVCSRTRGEVLEVAIGTGLNLPHYPDGVRLTGVDFSPAMLARARVRAGELGVAVELREADAQALPFEDGSFDTVLCALSLCGIPDNEAAIGEMYRVLRPGGRLLLLDHIGSSWPPIWLVQRLLEFVTVRGAGEYQTRRQLPLVVRAGFTVEESERLKAGSVERVAATKPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXH8</accession>
    <name>D3PXH8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1743</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017012.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1743"/>
    <dbReference type="EnsemblBacteria" id="ADD41441">
        <property type="protein sequence ID" value="ADD41441"/>
        <property type="gene ID" value="Snas_1743"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1743"/>
    <dbReference type="eggNOG" id="COG2315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105851_1_1_11"/>
    <dbReference type="OMA" id="NKRHWNT"/>
    <dbReference type="OrthoDB" id="1817663at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007351">
        <property type="entry name" value="YjbR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038056">
        <property type="entry name" value="YjbR-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35145">
        <property type="entry name" value="PTHR35145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04237">
        <property type="entry name" value="YjbR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142906">
        <property type="entry name" value="SSF142906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="115" mass="12965" checksum="F50AD22816EBF2B7" modified="2010-04-20" version="1">MTPDELRELLLSFTASVEGRPFTRHPEITTFKVSGKVFALARLDDKPMTVMLKCDPEEAIRLRQEHDAIVGGFNKRHWNYVTIDGSLPDDLIEELITDSYDLVVAGLPKSKRPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXJ5</accession>
    <name>D3PXJ5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3667</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3667"/>
    <dbReference type="EnsemblBacteria" id="ADD43325">
        <property type="protein sequence ID" value="ADD43325"/>
        <property type="gene ID" value="Snas_3667"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3667"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_2_2_11"/>
    <dbReference type="OMA" id="ETSLYWA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="188" mass="20017" checksum="C74F289ED242353E" modified="2010-04-20" version="1">MGKRERTRLRLQECAMDAFERDGFEATTVARIAEAAGVTPMTFFRHFPTKEAAVVWDPFDPLIAQAVAAAIAPDVSALQATCRGIWSAWRGADTAVEPLARRRSRLVAATPALRAAMWAAQADTEAAITEVLRDAGYTRWESAAAAGACLGALTSTLLAWALDADESSMNGAIASSLRALDPEGIPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXN5</accession>
    <name>D3PXN5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyoxalase-like_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018936.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3708"/>
    <dbReference type="EnsemblBacteria" id="ADD43365">
        <property type="protein sequence ID" value="ADD43365"/>
        <property type="gene ID" value="Snas_3708"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3708"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072991_1_0_11"/>
    <dbReference type="OMA" id="SENHCAM"/>
    <dbReference type="OrthoDB" id="1791609at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025870">
        <property type="entry name" value="Glyoxalase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13468">
        <property type="entry name" value="Glyoxalase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase-like_dom" evidence="1">
        <location>
            <begin position="9"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="33978" checksum="B504DAF909FBA3B3" modified="2010-04-20" version="1">MTTGDIIGLHHVGLLVGDMTAAIDTFRDLGFHIDAPAYPALPPVPGAAPEPIGAGNTHADFPRGFIELLAFAPDNRDLLPAEARLVPLAVPDEQLAATRAALRGTVGALERRLTRAEGAHILIFATADADKTAARLADVGVAHTGARPAQRPITTAEGTSLAAIKYLEISDDDPSGMPPEGRVGAAEDAPPELLDAQLGLDHPNGALGLTECVLCVSDTDLDATTGRYERYLGRTATRHGTGRGFDLGAHRLTITTPSGHTARLPGEPTPATPSLSAYTIDVADLAVAERLLRTRGIDLRQAATGEPFIPASAAHGAAILLRQASTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXY0</accession>
    <name>D3PXY0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_5679</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020880.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5679"/>
    <dbReference type="EnsemblBacteria" id="ADD45309">
        <property type="protein sequence ID" value="ADD45309"/>
        <property type="gene ID" value="Snas_5679"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5679"/>
    <dbReference type="eggNOG" id="COG1682">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060703_3_0_11"/>
    <dbReference type="OMA" id="GIFQLHH"/>
    <dbReference type="OrthoDB" id="1543624at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="9">
        <location>
            <begin position="32"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD45309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="294" mass="33248" checksum="5BF0D48C56B046DC" modified="2010-04-20" version="1">MNSPDTLVTSRPKRIFPKTTGLTALWRHRQTLRVLVQRDLAVKYQKTVMGYFWSLLEPMGLATIYWFVFGVVMQVGARGDSALEHVDYSLYIVSGIFAWMWASSAISEATTCLTSQSSLITTMKVPREVFPVARVVARFAEFLAGIPIIVIFALLGRGISAGTFGWNLLLLFPAVALQAVLLTGLAFILASLNVLYRDVQRFMRLVTRILFYAVPSIYPLALVLKSDNLPEWAKSIYLANPFVVIVEIHHEAWIPGLNNLTWQMITTSVAISVFLLFFGRWMFHRLEPMVLKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY15</accession>
    <name>D3PY15_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020915.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5714"/>
    <dbReference type="EnsemblBacteria" id="ADD45344">
        <property type="protein sequence ID" value="ADD45344"/>
        <property type="gene ID" value="Snas_5714"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5714"/>
    <dbReference type="eggNOG" id="ENOG5034BVZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1209202_0_0_11"/>
    <dbReference type="OMA" id="VHWDGTP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="229" mass="23899" checksum="8C54F9EC4A8CF1E9" modified="2010-04-20" version="1">MPETTPSPREELKHNRLMAGLEIVEAEAPPSEPPPADATVEHALAPIQAVWDGAEGGTPPMRALPVRTVIDKPPRRLPLVLPGLVVLALLAAFVSWVSAAPLWLTVGHAVEGTVTVKACDATGCHGVFTPADGQHATAVRVTGDQEAKQVGHSSQAQVTSSRATTAYTGDRAGLWWRVGIGLGLLVGLGFAVAAVTGAWRWHGRARLAAVLASLTAPLALFAAVFALTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY83</accession>
    <name>D3PY83_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1752</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017021.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1752"/>
    <dbReference type="EnsemblBacteria" id="ADD41450">
        <property type="protein sequence ID" value="ADD41450"/>
        <property type="gene ID" value="Snas_1752"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1752"/>
    <dbReference type="eggNOG" id="ENOG5032TID">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112381_0_0_11"/>
    <dbReference type="OrthoDB" id="1994921at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="151" mass="17112" checksum="3A4E7CD065553FEC" modified="2010-04-20" version="1">MSKDFDFLHGEWEVANRQLTKHLVGSDDWREFPARSSCRAFFDGSGNVDEITFPTLGSSGFTISSYEPKADRWSVYWISSRDGLMGPPVSGGFSDGVGTLYGDDVTGDGKPVRCRFLWTRITPTSARWEQAYSGDGEQTWETNWIMEFTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYM6</accession>
    <name>D3PYM6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Choloyl-CoA hydrolase</fullName>
            <ecNumber evidence="3">3.1.2.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3803</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the C/M/P thioester hydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.27" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3803"/>
    <dbReference type="EnsemblBacteria" id="ADD43459">
        <property type="protein sequence ID" value="ADD43459"/>
        <property type="gene ID" value="Snas_3803"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3803"/>
    <dbReference type="eggNOG" id="COG1946">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032690_0_0_11"/>
    <dbReference type="OMA" id="SQVWFRT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033882">
        <property type="term" value="F:choloyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066">
        <property type="entry name" value="PTHR11066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="291" mass="31809" checksum="BAA2CA57A3F9BCA3" modified="2010-04-20" version="1">MSEVLTGQPAVDGLLRVLDLEQIELNIFRGVGPQVSPQRVFGGQVAGQALVAAGRTVEAGRHVNSLHGYFVRPGDSTKPIVYEVERIRDGRSFSVRRTVAVQNGQTIFFMSASFHTGEDGLEHGETAPVDVPPPVEVPTLTERLASHPDRLGIWARIPRPIDVRYIGESGFAASGERHAATQQRVWMKVDGKLPDDPLLHVCVLTYASDLTLLDTVLNRHGQVWGPGGYAGASLDHALWFHRPFRADEWFLYDSASPSASRGRGLATGQFYTTDGRHIATTAQEGILRVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYU9</accession>
    <name>D3PYU9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative pre-16S rRNA nuclease</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3877</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YqgF HJR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019103.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3877"/>
    <dbReference type="EnsemblBacteria" id="ADD43532">
        <property type="protein sequence ID" value="ADD43532"/>
        <property type="gene ID" value="Snas_3877"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3877"/>
    <dbReference type="eggNOG" id="COG0816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098240_0_0_11"/>
    <dbReference type="OMA" id="PMGWTAQ"/>
    <dbReference type="OrthoDB" id="2075502at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000967">
        <property type="term" value="P:rRNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16964">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00651">
        <property type="entry name" value="Nuclease_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005227">
        <property type="entry name" value="YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33317">
        <property type="entry name" value="PTHR33317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03652">
        <property type="entry name" value="RuvX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00250">
        <property type="entry name" value="RNAse_H_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="YqgFc" evidence="3">
        <location>
            <begin position="8"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="151" mass="16177" checksum="E0B79BE386D3A73F" modified="2010-04-20" version="1">MNDTPPRGRRLGVDVGKVRVGVALSDPDGILAAPLETVPRDMSGKSVPPADISRIADLVNEHSVVEIVIGLPVTLSGEESYAAAESRAYAEQVTAAVGDVPVRFVDERLTTAVASRRLSERGVKGKRRKAVVDQAAAVEILQLWLEKQRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYV2</accession>
    <name>D3PYV2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019106.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3880"/>
    <dbReference type="EnsemblBacteria" id="ADD43535">
        <property type="protein sequence ID" value="ADD43535"/>
        <property type="gene ID" value="Snas_3880"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3880"/>
    <dbReference type="eggNOG" id="COG4768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132014_0_0_11"/>
    <dbReference type="OMA" id="FSYGVRR"/>
    <dbReference type="OrthoDB" id="2047474at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009293">
        <property type="entry name" value="UPF0478"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06103">
        <property type="entry name" value="DUF948"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="167" mass="17567" checksum="9041AB77B6398B23" modified="2010-04-20" version="1">MSGQAYAAASEFVTTGGELAALIAAGAFAALALVLAYVLLGLRKTVNAATRAVNDLNARTGPLLQKANTTMDHVNTALTQAHTSLDAVNTQLERVDTITGHAQQVTGNVANITSLVGAAATTPLVKLAAFGFGLRKALAKRRADDDEREVRNLLKDKKSRRKRSKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYY6</accession>
    <name>D3PYY6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5785</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020986.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5785"/>
    <dbReference type="EnsemblBacteria" id="ADD45415">
        <property type="protein sequence ID" value="ADD45415"/>
        <property type="gene ID" value="Snas_5785"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5785"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_1_7_11"/>
    <dbReference type="OMA" id="NWAINDA"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="186"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="401" mass="42344" checksum="5F654F97694FB4D8" modified="2010-04-20" version="1">MCAARRSPLRHVIDDWRGAPAFVGGLATVVATTALVVFGGSHAQGQVLADDAPGAIKDRYIVKSDADPSALAEEYHGKVRRTFAAYGGFSVTMDEADAREMAADPEVEYVNQVTTTTGLGDSVQSRPPSWSLDRIDQRTPARDGSFRYPDSAGRGVTAYVIDSGLKLDLREFSGRATTGIDVIDGGKALDRNGHGTSVAVTLGGQNFGVAKNVKLVAVRVLDEDWRGTNEGIVEGLNWIAEHAKGPSVANMSHSRAYDRAINDAVGAVVDAGVTTAVSAGNNSYNACRKSPPSEPSVIVAGATRRDDRKASFSNFGSCVDIFAPGVAVGTKNRLGQSIKSSGTSFAAPHVAGAAALYLAEHPRATPKQVRAALMDHALSKVVTDRGKYSPDRMLNIDFLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYZ6</accession>
    <name>D3PYZ6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020996.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5795"/>
    <dbReference type="EnsemblBacteria" id="ADD45425">
        <property type="protein sequence ID" value="ADD45425"/>
        <property type="gene ID" value="Snas_5795"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5795"/>
    <dbReference type="eggNOG" id="COG4991">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_161148_0_0_11"/>
    <dbReference type="OMA" id="TSCAING"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048702" evidence="1">
        <location>
            <begin position="31"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="123" mass="12947" checksum="79CB27A5DB248800" modified="2010-04-20" version="1">MKRFTRALTTAAAIVVLAFSGVAATSTAAAAGEVGALGCTATGADKDSTAYNKAFTTTVNIRSGRSTNCVALGVGYTSHTVDIHCSSYYGGTYWTYLRNVSTGVKGWVKTDLLDWPNHRLVIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ12</accession>
    <name>D3PZ12_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">L-2,4-diaminobutyric acid acetyltransferase</fullName>
            <shortName evidence="6">DABA acetyltransferase</shortName>
            <ecNumber evidence="4 6">2.3.1.178</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ectA</name>
        <name evidence="8" type="ordered locus">Snas_5811</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>acetyl-CoA + L-2,4-diaminobutanoate = (2S)-4-acetamido-2-aminobutanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16901"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58761"/>
            <dbReference type="ChEBI" id="CHEBI:58929"/>
            <dbReference type="EC" id="2.3.1.178"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Amine and polyamine biosynthesis; ectoine biosynthesis; L-ectoine from L-aspartate 4-semialdehyde: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the acetyltransferase family. EctA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.178" evidence="4 6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5811"/>
    <dbReference type="EnsemblBacteria" id="ADD45441">
        <property type="protein sequence ID" value="ADD45441"/>
        <property type="gene ID" value="Snas_5811"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5811"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111896_0_0_11"/>
    <dbReference type="OMA" id="DGAAIWR"/>
    <dbReference type="UniPathway" id="UPA00067">
        <property type="reaction ID" value="UER00122"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033816">
        <property type="term" value="F:diaminobutyrate acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019491">
        <property type="term" value="P:ectoine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012772">
        <property type="entry name" value="Ectoine_EctA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02406">
        <property type="entry name" value="ectoine_EctA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="179" mass="19636" checksum="8372911019AE0A8D" modified="2010-04-20" version="1">MSLGDTLAPVLRRNGGSAVGFEPPTIRDGERLWQLALDSRTLDVNSRYSYLLWCRDFAETSVVARHDGEAVGFITGYRRPGSPGTLFIWQVAVADSHRRQGLARRMLDNLAARLIPQGITALEATVTPDNLPSTRLFTSFAEARGAELTRDELFSGQLLGEGHLAEILFRIAPLSPASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ36</accession>
    <name>D3PZ36_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exo-alpha-sialidase</fullName>
            <ecNumber evidence="4">3.2.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5835</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.18" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5835"/>
    <dbReference type="CAZy" id="GH33">
        <property type="family name" value="Glycoside Hydrolase Family 33"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45465">
        <property type="protein sequence ID" value="ADD45465"/>
        <property type="gene ID" value="Snas_5835"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5835"/>
    <dbReference type="eggNOG" id="COG4409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024620_1_0_11"/>
    <dbReference type="OMA" id="WSPTEFI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052794">
        <property type="term" value="F:exo-alpha-(2-&gt;3)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052795">
        <property type="term" value="F:exo-alpha-(2-&gt;6)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052796">
        <property type="term" value="F:exo-alpha-(2-&gt;8)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026856">
        <property type="entry name" value="Sialidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10628">
        <property type="entry name" value="PTHR10628"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048483" evidence="2">
        <location>
            <begin position="30"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Sialidase" evidence="3">
        <location>
            <begin position="58"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="392" mass="41432" checksum="066A0E0C1E8D1D1A" modified="2010-04-20" version="1">MRLLRPLVIAAVAALTVTAGLLTAGPASAAPDVQTIFTKGENGYGCHRIPAILRAGNGDLLAFAEARTEFCGDTGHIDLVMKRSTDDGATWGKSQIVLQGTDDDPDAAATRGNPVPILDESTGRIVLLSTHNPSNADQPRTPYVQHSDDDGQTWSTAKSLGDVIDEPDWGWYATGPGGGIQLTRGEHAGRLVVGVNFSDGSGKNGAALVYSDDGGETWTRGATDVPATDDIIPQELNLFERTDGGIYAAARENAGTNTQTRAFAVSTDAGASFEAPFKLIPDLVGTPKVQGSILRLRATDSGDSYDRVLFASPVHSKLRMTMTIRSSFDEGKTWQSVDEGTVIDEDRAGYSNMAVLGNGDIGLLYEAGAYPDGDARDDIRFARISESDLGVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZK0</accession>
    <name>D3PZK0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017245.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1978"/>
    <dbReference type="EnsemblBacteria" id="ADD41674">
        <property type="protein sequence ID" value="ADD41674"/>
        <property type="gene ID" value="Snas_1978"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1978"/>
    <dbReference type="eggNOG" id="COG1233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019327_0_1_11"/>
    <dbReference type="OMA" id="HNFLVHN"/>
    <dbReference type="OrthoDB" id="453021at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="534" mass="57622" checksum="A3BD62875DAE0E1E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZK6</accession>
    <name>D3PZK6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1984</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017251.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1984"/>
    <dbReference type="EnsemblBacteria" id="ADD41680">
        <property type="protein sequence ID" value="ADD41680"/>
        <property type="gene ID" value="Snas_1984"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1984"/>
    <dbReference type="HOGENOM" id="CLU_1004392_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="277" mass="30041" checksum="AFA68DDEF0E4B2F5" modified="2010-04-20" version="1">MTGLGGLLERYRTARPAARAGVAGVVAILLLAAGLAVAARNHPRAPDSQAEVDRVGERLDAANPWEARAKSRDDGTVRVREWGFARLSEPEVRGKIGYAVSVVVENTSRVDAVVPRLDFDVRDEAGRPAELNDVNDGVTDQVIPPGVRLGITGTIHLDEPVAEEVSVSPGVSDWYPAREDIGEVEAVDVRVREDDDSLRVGLESSYDMTLLAPTFQALFRDEAGNLVGGTRLFSSDFNATVPPGSSRHDFALETWPEDADPDAIEVYVLYDWTVFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZZ9</accession>
    <name>D3PZZ9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021099.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5900"/>
    <dbReference type="EnsemblBacteria" id="ADD45528">
        <property type="protein sequence ID" value="ADD45528"/>
        <property type="gene ID" value="Snas_5900"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5900"/>
    <dbReference type="eggNOG" id="COG2318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097062_2_0_11"/>
    <dbReference type="OMA" id="DWEWHSA"/>
    <dbReference type="OrthoDB" id="2047691at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007061">
        <property type="entry name" value="DUF664"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04978">
        <property type="entry name" value="DUF664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="189" mass="21077" checksum="70634DC9E6CFDAAE" modified="2010-04-20" version="1">MSDNDEQIPTEPPLAGEETAALIGSLERQRRLFAWKCGDLDAEGLRLRIGASSITLGGLLKHLALVEDDHFARLWQGRETGPPPPWDTVDWDAEPDWDWKSAVDDTPEQLRAGWRAAVARSRERIADGVVTGDMGRLGRFTTDDGGAPNLRRILIDMIEEYSRHNGHADLIREAVDGRVGEDPPRDFVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q009</accession>
    <name>D3Q009_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxidoreductase alpha (Molybdopterin) subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5910</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021109.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5910"/>
    <dbReference type="EnsemblBacteria" id="ADD45538">
        <property type="protein sequence ID" value="ADD45538"/>
        <property type="gene ID" value="Snas_5910"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5910"/>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_16_1_11"/>
    <dbReference type="OMA" id="DCSDLCH"/>
    <dbReference type="OrthoDB" id="50471at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02787">
        <property type="entry name" value="MopB_CT_ydeP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02767">
        <property type="entry name" value="MopB_ydeP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037951">
        <property type="entry name" value="MopB_CT_YdeP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010046">
        <property type="entry name" value="Mopterin_OxRdtse_a_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041953">
        <property type="entry name" value="YdeP_MopB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF4">
        <property type="entry name" value="PTHR43105:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01701">
        <property type="entry name" value="Fdhalpha-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Molybdopterin" evidence="5">
        <location>
            <begin position="116"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="6">
        <location>
            <begin position="632"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="747" mass="81185" checksum="33FD0FF93884CE51" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q085</accession>
    <name>D3Q085_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5988"/>
    <dbReference type="EnsemblBacteria" id="ADD45614">
        <property type="protein sequence ID" value="ADD45614"/>
        <property type="gene ID" value="Snas_5988"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5988"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_697626_0_0_11"/>
    <dbReference type="OMA" id="GHFDRAC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048756" evidence="1">
        <location>
            <begin position="25"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="381" mass="39396" checksum="918EF6C9EF6D0A14" modified="2010-04-20" version="1">MRRLLAVIGAVVALVFAAQVAAFAEPVPESLAAQPIAGATFKGPVHALAYARGKFFVGGEFAEAVADGKLQQRTHLAAVSPEGDLEVFSPELNGPVYALATGSHYLYVAGRFTEANGHPARHLARFSLRTGAVDRDFDVSVNALPRALELDGTRLYIGGDFNTVNGQPRGKVAAVSTGTGGLVGDFAPMFDRGVRTLEAANGKLYVGGGFTAVGDTQVRKLAALNPDSGAVYSSFDPQDKGLVYDIDAYDGRIYAATGGQGGRVMAYDSGGGTDWERITDGDVTAVSVSRGVVVAGGHFDRLCAGDDLGANGRCLDGVFAERGKLFAVSTGNSVHSWNPGANSVTGTHFLARGGGVLAAGGSFSTFAGGEINRRGLALFPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0A6</accession>
    <name>D3Q0A6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0434 protein Snas_6009</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0434 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021206.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6009"/>
    <dbReference type="EnsemblBacteria" id="ADD45635">
        <property type="protein sequence ID" value="ADD45635"/>
        <property type="gene ID" value="Snas_6009"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6009"/>
    <dbReference type="eggNOG" id="COG2835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155659_4_1_11"/>
    <dbReference type="OMA" id="PTHRHEM"/>
    <dbReference type="OrthoDB" id="1834382at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01187">
        <property type="entry name" value="UPF0434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="73" mass="7832" checksum="FF139943ACC51476" modified="2010-04-20" version="1">MPTLDPALLEVLACPDTHHAPLTYDSAAQTLTCTECRRIFRIDDGIPVLLLDEATEPKPGDGAVPEDANTEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0F4</accession>
    <name>D3Q0F4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0097</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015389.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0097"/>
    <dbReference type="EnsemblBacteria" id="ADD39818">
        <property type="protein sequence ID" value="ADD39818"/>
        <property type="gene ID" value="Snas_0097"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0097"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="AMSETVQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="356"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="13"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD39818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="516" mass="52644" checksum="670D805AA4CB3B17" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0H6</accession>
    <name>D3Q0H6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2017"/>
    <dbReference type="EnsemblBacteria" id="ADD41712">
        <property type="protein sequence ID" value="ADD41712"/>
        <property type="gene ID" value="Snas_2017"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2017"/>
    <dbReference type="eggNOG" id="COG0759">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1151246_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002696">
        <property type="entry name" value="Membr_insert_effic_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33383">
        <property type="entry name" value="PTHR33383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01809">
        <property type="entry name" value="YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01234">
        <property type="entry name" value="Haemolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="241" mass="25674" checksum="685B565DB8CCEDC0" modified="2010-04-20" version="1">MVRPRPLRKITTLMDDDTPEKRRTPLALTVTLASGGVVLLMGLVGGLLWLIWRPGTEPPQPQETSEPPRDLGDGADGGGGTAEPDTPENNDAEEADGGSEVDASGCDDDLSCDGPTCDSPSCETQSCDSPSCDSGTGVVSAGVSVMSVLPLVTVDRFTPRRPMRKRASVSRPARCGLAAIRGYRRWVSPRTRTRCRYVPSCSGYGTATIRSYGLANGSRLALRRIRRCTRSVPMGTVDPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0S0</accession>
    <name>D3Q0S0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmB</name>
        <name evidence="5" type="ordered locus">Snas_2112</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017377.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2112"/>
    <dbReference type="EnsemblBacteria" id="ADD41806">
        <property type="protein sequence ID" value="ADD41806"/>
        <property type="gene ID" value="Snas_2112"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2112"/>
    <dbReference type="eggNOG" id="COG0227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064548_7_0_11"/>
    <dbReference type="OMA" id="MKVCTSC"/>
    <dbReference type="OrthoDB" id="2062238at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribo_L28/L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribo_L28/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_L28"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="63" mass="6932" checksum="28B4275703C300A4" modified="2010-04-20" version="1">MSRKCEVCGKGPGFGHNVPWSKKKTNRRWNPNLQSVRASTGSGDNLKRVKVCTSCLKAGKVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0S6</accession>
    <name>D3Q0S6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphopantetheine adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dephospho-CoA pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantetheine-phosphate adenylyltransferase</fullName>
            <shortName evidence="6">PPAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaD</name>
        <name evidence="9" type="ordered locus">Snas_2118</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="2.7.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the bacterial CoaD family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.3" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2118"/>
    <dbReference type="EnsemblBacteria" id="ADD41812">
        <property type="protein sequence ID" value="ADD41812"/>
        <property type="gene ID" value="Snas_2118"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2118"/>
    <dbReference type="eggNOG" id="COG0669">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100149_0_1_11"/>
    <dbReference type="OMA" id="EFQMALM"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004595">
        <property type="term" value="F:pantetheine-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02163">
        <property type="entry name" value="PPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00151">
        <property type="entry name" value="PPAT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001980">
        <property type="entry name" value="PPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21342:SF1">
        <property type="entry name" value="PTHR21342:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01020">
        <property type="entry name" value="LPSBIOSNTHSS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01510">
        <property type="entry name" value="coaD_prev_kdtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="8">
        <location>
            <begin position="19"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="23"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="102"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="136"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD41812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="173" mass="18880" checksum="7120D7B22CD5EEC8" modified="2010-04-20" version="1">MDLNQGAPSDQTPANRRALCPGSFDPTTNGHLDIINRTAKLYDHVYAAVFVNPSKPGLFSMDERMEMLQEVTGHLPNVSVASFKGLTVDFCREHDVGVIVKGQRAVSDFDYEQQMAQMNYGQAGVETLFMPTNPLYSFLSSSLVKDVAKWGGDVSSHVPAPVAARLVTRFGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0S7</accession>
    <name>D3Q0S7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2119"/>
    <dbReference type="EnsemblBacteria" id="ADD41813">
        <property type="protein sequence ID" value="ADD41813"/>
        <property type="gene ID" value="Snas_2119"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2119"/>
    <dbReference type="eggNOG" id="COG0711">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078484_2_1_11"/>
    <dbReference type="OMA" id="GAREYAD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="173" mass="19458" checksum="DA58D88EE40B3292" modified="2010-04-20" version="1">MEYRVGPLDRIEDIVAYVEAAKAIPMSRNCKVDRAEIIGMLEELRGELPGELRRADAMLAERDKIIEAGEKEAERIIAEAEDEHARLVSAHEVVVSAEREGHRIVSEARNEAQRLRDEVDEYVDTTLANFEQFLQRALAGVERGRDKMHALREIGSFAGPSQQAEPEKPLPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0X8</accession>
    <name>D3Q0X8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4076</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019299.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4076"/>
    <dbReference type="EnsemblBacteria" id="ADD43728">
        <property type="protein sequence ID" value="ADD43728"/>
        <property type="gene ID" value="Snas_4076"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4076"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_11"/>
    <dbReference type="OMA" id="GNFFVPY"/>
    <dbReference type="OrthoDB" id="1510342at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="83"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="288" mass="31552" checksum="2F9CE9CEEFF37CEB" modified="2010-04-20" version="1">MSTTTEQPTDTGRRRKLLTGLAANVGLIAYFAFSLMPVVFILALSFKADADQTTTYLLFDPTLDNYKTVLGFDDGGSSYLRFFMASLITSVGAVVVSLVIGIPAAYAAARYRFRGSDNLMFTLLSFRFAPELLVIIPLAVLYQQLGLYDTWVGMIWVLQLVTMPLVVWILRSFFQDFPAELEEAALLDGYSRTRAFAKHVLPLVRPGIAAVSLLAFIFAWNNFIFPFTLTSSNAQTVTVSSLAYLGGNQVRFNLVAAGAVMAALPPLVLALLIQRYLVRGLSFGAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q102</accession>
    <name>D3Q102_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenosine deaminase</fullName>
            <ecNumber evidence="4">3.5.4.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4101</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.4" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019323.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4101"/>
    <dbReference type="EnsemblBacteria" id="ADD43752">
        <property type="protein sequence ID" value="ADD43752"/>
        <property type="gene ID" value="Snas_4101"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4101"/>
    <dbReference type="eggNOG" id="COG1816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039228_7_1_11"/>
    <dbReference type="OMA" id="EGIFSPW"/>
    <dbReference type="OrthoDB" id="554648at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009168">
        <property type="term" value="P:purine ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114">
        <property type="entry name" value="PTHR43114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A_deaminase" evidence="3">
        <location>
            <begin position="9"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="329" mass="34898" checksum="78F56A2863D59599" modified="2010-04-20" version="1">MTPLQRDCPKIELHVHVEGTARPPTLGRIATRNGLDVPPRRPFTDLYEFIASYSEVAARLREPRDYRDLILAYAAEAATGGAVYIEAIVCATDERMGGAAGWADILAVSCDAADEASERFDLEFNLTPEVYRGCDPEFATAATKAVTAIDHPRIVGFGLSGFEGREPATPYLNAARIAVDAGLGFVPHAGEAAGPPSIREVLALRPPRIRHGVRAIEDPELVAELAETGTVLDVTLTSNLLLGVTTDLASHPLPLLRNAGVACSISTDDPALFDTDLPREYDLAATLGTTPPEAFAAGLSGALCSAAVKARLASISRAAFRRGSEPSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q119</accession>
    <name>D3Q119_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome bc1 complex Rieske iron-sulfur subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Cytochrome bc1 reductase complex subunit QcrA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Rieske iron-sulfur protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Snas_4118</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Rieske iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019340.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4118"/>
    <dbReference type="EnsemblBacteria" id="ADD43769">
        <property type="protein sequence ID" value="ADD43769"/>
        <property type="gene ID" value="Snas_4118"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4118"/>
    <dbReference type="eggNOG" id="COG0723">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050668_0_0_11"/>
    <dbReference type="OMA" id="LGCPTSL"/>
    <dbReference type="OrthoDB" id="1632945at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045603">
        <property type="entry name" value="QcrA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="PTHR10134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19297">
        <property type="entry name" value="QcrA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="15">
        <location>
            <begin position="279"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ADD43769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="364" mass="40185" checksum="9255E1DB789A5AD6" modified="2010-04-20" version="1">MSNDKQHSSDEIDVTDPKLTKFDIVKEGLRRDGIEILHYEPAFPKAGTAEEKRIERFIAFCFTLTGLGALGFVVTYIFWPWEYVEGNASELSKWYTPMLGLCLGVALAGLGIGILTWAKKLLPKEELVQDRHDGGSSEEDRKITGATVSNVVDETGIKRRPMLKRALLFGSAPLGLAAIAPLGALIVPPGDDRDHTGFDAKKYNDGNPVRLILKDGTPVRPDMVSVGGQVTVYPEIPHGTTNKHADSPTLLIHLRDADSKEAAKYIKKNDKKYAESNWNNFFAFSKICTHVGCPASLYEQQTNRLLCPCHQSQFDIIQGAKPIFGPATRSLPQLPIDVGDDGVFYAKSDFLVPVGPAFWERDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1U2</accession>
    <name>D3Q1U2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015511.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0221"/>
    <dbReference type="EnsemblBacteria" id="ADD39940">
        <property type="protein sequence ID" value="ADD39940"/>
        <property type="gene ID" value="Snas_0221"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0221"/>
    <dbReference type="eggNOG" id="COG1426">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_8_2_11"/>
    <dbReference type="OMA" id="NRQVPTL"/>
    <dbReference type="OrthoDB" id="2063007at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="22"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="115" mass="12445" checksum="B6F0899A5A9E4ABB" modified="2010-04-20" version="1">MDVNAIPHTPRPLLRTILGGVLRGIRRHQGRTLSDVADAARVSMQYLSELERGRKEASSEILAAVCEALRVELSDVLAEVGRVMMAQRVRHASISVARQTAATRASSPQAYALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1U8</accession>
    <name>D3Q1U8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_0227</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015517.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0227"/>
    <dbReference type="EnsemblBacteria" id="ADD39946">
        <property type="protein sequence ID" value="ADD39946"/>
        <property type="gene ID" value="Snas_0227"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0227"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_22_1_11"/>
    <dbReference type="OMA" id="HAWSKER"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="7">
        <location>
            <begin position="12"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="8">
        <location>
            <begin position="120"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD39946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="303" mass="32726" checksum="93CB40B8331D47AD" modified="2010-04-20" version="1">MVDELGEAARRFEENRARLRAVAYRMLGSLAEAEDAVQETWLRYSRADTAEVANLPGWLTTVTGRVCLNMLRARRTRREVSIDAVTDDGRRGADTELERHPATDADPEREAVMADSVGLALLVLLDTLSPGERLAFVLHDMFTVPFEEIAPLVDRSAAATRQLASRARRRVKGGAAVSRAELDRQRPVVDAFLTAVRGADLEALVALLDPSVTLRADRHVVPSARPITISGATTVAETAMAATGRARFTGLVLIDGAVGLLMAPGGRLRLVLRFGFDGERITGIDVVADPARLAELELAVVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1W1</accession>
    <name>D3Q1W1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017399.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2134"/>
    <dbReference type="EnsemblBacteria" id="ADD41828">
        <property type="protein sequence ID" value="ADD41828"/>
        <property type="gene ID" value="Snas_2134"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2134"/>
    <dbReference type="eggNOG" id="ENOG5032SDA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_908887_0_0_11"/>
    <dbReference type="OMA" id="GYCVINS"/>
    <dbReference type="OrthoDB" id="1908403at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="159"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="315" mass="32867" checksum="406CF8ED05F6EE50" modified="2010-04-20" version="1">MKYALLIIAAAALQATGNGLLTGNIDGSESIVLSFCAFGSSAIIFGLLNQRRRLTSTAAPPPGNVRVPLLLMNIATALAFIGLYWSYSMFPAPLASATGIAIGPLSVSLIDRLTGGSRRSNGELVVGAVSLGLVLAVASRSISLGTVALDGAFVLGFGIAIAAGALFACIPILSHRLGTTGVGPVRILAHRYHLTYIAAFAILMATPHAAMDTITGPRLPFIACVALIGVALPIFLLQLSMKHVQPVFLALIFSIQPSLTYLAAVVATELRFDAISFVLINASLCVAFGGPLLLHRRERARRARPALRPTTTTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q225</accession>
    <name>D3Q225_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor</fullName>
            <shortName evidence="3">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">frr</name>
        <name evidence="5" type="ordered locus">Snas_2201</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RRF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017463.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2201"/>
    <dbReference type="EnsemblBacteria" id="ADD41892">
        <property type="protein sequence ID" value="ADD41892"/>
        <property type="gene ID" value="Snas_2201"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2201"/>
    <dbReference type="eggNOG" id="COG0233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073981_2_0_11"/>
    <dbReference type="OMA" id="FNPMNNG"/>
    <dbReference type="OrthoDB" id="1674344at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="SSF55194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRF" evidence="4">
        <location>
            <begin position="21"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="21061" checksum="75AD63D3BB605C57" modified="2010-04-20" version="1">MIDETLFDAEEKMDGSIEHAKEEFAAIRTGRASAAMFSKIVVDYYGSPTPLPQLASIAVPEPRMVIIKPYDVSQTDALERAIRDSDLGVNPNNEGNQLRLFVPQMTEERRREMIKVARHKAEESKIAVRNVRRKAKEELERLVSDGEVGEDEGHRAEKDLDELTQRHIKLIDELVAHKETELLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q254</accession>
    <name>D3Q254_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2231"/>
    <dbReference type="EnsemblBacteria" id="ADD41921">
        <property type="protein sequence ID" value="ADD41921"/>
        <property type="gene ID" value="Snas_2231"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2231"/>
    <dbReference type="eggNOG" id="ENOG5030J65">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1288240_0_0_11"/>
    <dbReference type="OMA" id="TRSFAGW"/>
    <dbReference type="OrthoDB" id="1583842at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="214" mass="23020" checksum="964B4BB0581F6B10" modified="2010-04-20" version="1">MFAVVALTGCIKVDLAATIKPDDTVDGELTAAVNIEALDAIGDEEADEFVKALTDDIPGATRAEPYNDGEFVGKTVHFADVPLAKFNASETDEAEDAQLSITHDEGHYILNGEWDLPRADTGGSFPDLDKEIVNSAEFSVKVTFPGPVIAHNGDLDGQTVTWNLELGKNNILRAESDQASNTALALWVLAIMVVLTLLVMLLLYLQLRRHSVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q259</accession>
    <name>D3Q259_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine protein kinase with PASTA sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2236</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017497.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2236"/>
    <dbReference type="EnsemblBacteria" id="ADD41926">
        <property type="protein sequence ID" value="ADD41926"/>
        <property type="gene ID" value="Snas_2236"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2236"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_469211_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03793">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00740">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51178">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="4">
        <location>
            <begin position="459"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="535" mass="55870" checksum="614C03686A6FA9AF" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2F7</accession>
    <name>D3Q2F7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-L-isoaspartate O-methyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Protein-beta-aspartate methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4241</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019461.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4241"/>
    <dbReference type="EnsemblBacteria" id="ADD43890">
        <property type="protein sequence ID" value="ADD43890"/>
        <property type="gene ID" value="Snas_4241"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4241"/>
    <dbReference type="eggNOG" id="COG2518">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_811143_0_0_11"/>
    <dbReference type="OMA" id="LNPGHTE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="33387" checksum="189CBA1857C31A5D" modified="2010-04-20" version="1">MTTLAEAITAVDTDQYVNEPDGRPLPQSSAPAIIESLLRLADIQNGHRVCEVGTGSGYSTKIAATVVGPTGAVVSVEVDPAVAARAETKLADTPQVTVMCGDGGLGAPDAAPFDRLIAWTTPRVIPAPWVRQMRDGGVIVTPVKVAPVAMANLTVRMTVTGGQPATVHVHEGSFVDLTPSAADQRVPAFYLDATADTGGDIPAWLSAPAVRDNGAAAARLLDGLMNHATTMTTEAASFPVLVAALAAARPHQLATAYTGHTRGIGYATPDSIAVATPEGILSYGTSETRDALVADLPAADATLADYTAATAPDDDGWTVAVTGRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2G3</accession>
    <name>D3Q2G3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4247"/>
    <dbReference type="EnsemblBacteria" id="ADD43896">
        <property type="protein sequence ID" value="ADD43896"/>
        <property type="gene ID" value="Snas_4247"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4247"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055817_1_1_11"/>
    <dbReference type="OMA" id="TRYSPTI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043917">
        <property type="entry name" value="DUF5753"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19054">
        <property type="entry name" value="DUF5753"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="64"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="410" mass="46376" checksum="DE33E92EFA89E73C" modified="2010-04-20" version="1">MVTSHCDVYDLRSVTSCHTESRNAMCVFRLGVVRFSYCELMRHNERMTARKSLTVRKRRLVRALRQLRKDSGITLEKAAEHLDINHTSLSRIETGVAAVKLPYVESLLRLYGVPEARQEELLQLTREAKQRGWWQAYKDILSSEYADFIGFETEANETRTYELDTVPGLLETEDYARALISAQLPGATAEDIEKRVKLRASRQDRLKEDPKLSVWAILGEAALRYQVGGMKVLRAQLEYLLQLQREPNITIQVLPFSAGAHPGMAGPFVILGFDDDPDIVYLEGLTSALYLEDLGELERYKMVFERLLAEALSPAASDRLIREASKELCHFANNGRRRGMAAQGDDLARARWRKGRRTQANGNCVEVALVESVYVRDSKLDTTGTFPTLSVSSTEWKNFLLAIANNDKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2M3</accession>
    <name>D3Q2M3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_6151</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021345.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6151"/>
    <dbReference type="EnsemblBacteria" id="ADD45774">
        <property type="protein sequence ID" value="ADD45774"/>
        <property type="gene ID" value="Snas_6151"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6151"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_2_11"/>
    <dbReference type="OMA" id="IGFNYIF"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="108"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="318" mass="33177" checksum="1E27027B29E21A72" modified="2010-04-20" version="1">MSAKTDKIDRLAELTAGHDLSGKGAGLWTEAFRRLRRSPMAIIGATIIIVFVILAIVGPFIAPHSPTALTWGDEVSPARSEFVGPRAGNILGLDHLGRDEFSRLLIGARQSLMVGVIATGIGFIIGAVIGGISGAAMGLGGKVGKSIDNAIMRFIDMMLALPSLLLALSIAAVLGPSLTSVMIAVGTVQIPIFARLLRGSMIAQSHGDYVLAAEALGVRRRRIVLAHIVPNSLGPIIVQATLSLATAIIEAAALSFLGLGNPDSAAPEWGVMLAQSQRYLSDAIELAVYPAGAIIITALGFTLLGESIREALDPKLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2N3</accession>
    <name>D3Q2N3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylmalonyl-CoA mutase, large subunit</fullName>
            <ecNumber evidence="4">5.4.99.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6161</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.2" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021355.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6161"/>
    <dbReference type="EnsemblBacteria" id="ADD45784">
        <property type="protein sequence ID" value="ADD45784"/>
        <property type="gene ID" value="Snas_6161"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6161"/>
    <dbReference type="eggNOG" id="COG1884">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009523_5_1_11"/>
    <dbReference type="OMA" id="CAYDEAL"/>
    <dbReference type="OrthoDB" id="154460at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004494">
        <property type="term" value="F:methylmalonyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006098">
        <property type="entry name" value="MMCoA_mutase_a_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00641">
        <property type="entry name" value="acid_CoA_mut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="METMALONYL_COA_MUTASE" evidence="3">
        <location>
            <begin position="3"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="495" mass="53264" checksum="C27B183656602BF3" modified="2010-04-20" version="1">MTEKPGEFPYTRGISAQAKPWIMGQYAGFATAAESNRRFKELLEAGQTGFSVALDLPTQLGLDSDDPKALGEVGRVGVAIDSLADVETLMDGIPLERISQVRTTANSIGFVWAALCLALARRRGVDPGDFGVFIQNDVLKEYIARGTQIFPAEPALRLTVDTMEHLSRHVPGWVPLAMSGYHIAEAGGDDATEIGYTFANAIAYLDEAVSRGVDIDQLAPSLFTFLSVGMDIFGEVAKLRAARRVWAKLVTERYGAKDPRSAQLRIFAFTAGSSLTAQQPLNNVARTSLEAFAAACGGVQTLHVCAYDEALGVPTAQAATLALRTQQIVAHETGFADIPDPLGGSYLVESRTDDCERRIRGVMDDLANRGGALAGIESGYQQSRLAESAYRQAREVEEGDRIVVGVNRWAADPEPLDVFRIDPAAEAGQVKALHHLRETRDSQAVATTLDALSEAARAGDNIVPFCVEAVEAYATIGEIVARLREVHGSWTPTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q319</accession>
    <name>D3Q319_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0271"/>
    <dbReference type="EnsemblBacteria" id="ADD39989">
        <property type="protein sequence ID" value="ADD39989"/>
        <property type="gene ID" value="Snas_0271"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0271"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_2_1_11"/>
    <dbReference type="OMA" id="YHPEVPP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="19"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="140" mass="16116" checksum="5BE745AA8783DE1E" modified="2010-04-20" version="1">MSDKTTRPVPIDVDPELACPIAPVVDIVFSRWTTPILWALNEFGRQRFVELERAITTITPKVLTQRLRQLERDGLVSRAYYPEVPPRVEYEITELGRSLAPLFASLAEWSVNLDKVEQARRDYDERVHGSRRGTPPSTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q344</accession>
    <name>D3Q344_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015585.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0296"/>
    <dbReference type="EnsemblBacteria" id="ADD40014">
        <property type="protein sequence ID" value="ADD40014"/>
        <property type="gene ID" value="Snas_0296"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0296"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_9_0_11"/>
    <dbReference type="OMA" id="WQAVEAN"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="39"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="304" mass="32917" checksum="A2BEC8DF11097B59" modified="2010-04-20" version="1">MTNNSTSSSRLAPPPVGGFAEIDGRRLFVHQSGDGGPAVVFLPGASAIGFDYYLPQQEAAKFATAVIYDRGGSGYSDPMPLPRTAEAVATELRDLLHAQNIPGPYVLVAHSLGGAYAQRFAQLYPTEVAGLVWVDAFVSNWDDFVPASNSLAASEEMAPTREQLEQALPVMREYVTAMFADFPTDVREALVDYHVSDVWVTVGIAERTKLDVLADEINAGPNLPDVPVIALTPVAVDPNQAALMSEEELRVMHDGKIKMHRALVDSVSNGEQRILEDADHSNITFKRVDAVVQAISDVIDRATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q394</accession>
    <name>D3Q394_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015635.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0346"/>
    <dbReference type="EnsemblBacteria" id="ADD40064">
        <property type="protein sequence ID" value="ADD40064"/>
        <property type="gene ID" value="Snas_0346"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0346"/>
    <dbReference type="HOGENOM" id="CLU_2411758_0_0_11"/>
    <dbReference type="OrthoDB" id="2095270at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="92" mass="10310" checksum="3D4E03633BD512D1" modified="2010-04-20" version="1">MNNALSRFGSDILGKCCWALKYNDGHPNGAWSTGEKLAVALVLDDEEFLTAEDYTIPEAKQRVFGGSWEWRNTNEFDTWLAQLRALLGNNSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3A1</accession>
    <name>D3Q3A1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2253</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2253"/>
    <dbReference type="EnsemblBacteria" id="ADD41942">
        <property type="protein sequence ID" value="ADD41942"/>
        <property type="gene ID" value="Snas_2253"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2253"/>
    <dbReference type="eggNOG" id="COG3963">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085338_2_1_11"/>
    <dbReference type="OMA" id="RIWMNLP"/>
    <dbReference type="OrthoDB" id="2030110at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="4">
        <location>
            <begin position="45"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="199" mass="21333" checksum="8FE96165270F04DA" modified="2010-04-20" version="1">MSAESTVFLREFLRTPMRTGALLPSSARLASAVVAPIPRRGDPVVVELGPGTGAFTAAIRQRLAGRGHQLAVELNPRLAEYTARRFTGVDVVTADAARLPAILAERGLPGADVVVSGLPWASFPRPVQQSILDAIRGGLAEGGAFTTFAYSHARVLSSARRFRRSLEAGFEEVLCGRTIWRNIPPAMVYVSRRPKGNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3B0</accession>
    <name>D3Q3B0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017522.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2262"/>
    <dbReference type="EnsemblBacteria" id="ADD41951">
        <property type="protein sequence ID" value="ADD41951"/>
        <property type="gene ID" value="Snas_2262"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2262"/>
    <dbReference type="eggNOG" id="COG3408">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_396841_0_0_11"/>
    <dbReference type="OMA" id="HQWNGAY"/>
    <dbReference type="OrthoDB" id="116366at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="706" mass="75443" checksum="3C71EABBE6133D59" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3C4</accession>
    <name>D3Q3C4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">eIF-2B alpha/beta/delta-related uncharacterized protein</fullName>
            <ecNumber evidence="3">5.3.1.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.23" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017536.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2276"/>
    <dbReference type="EnsemblBacteria" id="ADD41965">
        <property type="protein sequence ID" value="ADD41965"/>
        <property type="gene ID" value="Snas_2276"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2276"/>
    <dbReference type="eggNOG" id="COG0182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016218_2_0_11"/>
    <dbReference type="OMA" id="RLWVDET"/>
    <dbReference type="OrthoDB" id="1290468at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046523">
        <property type="term" value="F:S-methyl-5-thioribose-1-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011559">
        <property type="entry name" value="Initiation_fac_2B_a/b/d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00524">
        <property type="entry name" value="eIF-2B_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="348" mass="37328" checksum="D9D71DD945D571A8" modified="2010-04-20" version="1">MAESSIHVPVPTLISQSVLIEPDAVRILDRRVFPFERTWVSCATYQEVAQAIEDMVTQSNGPLFAAAGGMTLAARAADALPGENRRAYLTEAADRLRATRPTHNGIREVVDAILRAAEPSLAAREPVAEVVEQAAVAAGDRHFARCRQLGEAAAELLDDGDTVLTHCWGESYVTEPVAAALRAGKRLRMVCTETRPYLQGARLTAESLAEMGVETVVVTDAMPAELMSRGEIDKVITGADRVTMDGHVINKVGTLQIAIAAHAFGVPYVAVVTAPDAQAPTPEAVPLEYRDGNEVLHALGHRTASTRATGIYPAFDVTPPRYVSTVATDRGRFSPNDLASYYNTDAPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3K7</accession>
    <name>D3Q3K7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA-specific 2-thiouridylase MnmA</fullName>
            <ecNumber evidence="7">2.8.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mnmA</name>
        <name evidence="8" type="ordered locus">Snas_2363</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:47032"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:11728"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:87170"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.13" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2363"/>
    <dbReference type="EnsemblBacteria" id="ADD42048">
        <property type="protein sequence ID" value="ADD42048"/>
        <property type="gene ID" value="Snas_2363"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2363"/>
    <dbReference type="eggNOG" id="COG0482">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035188_0_2_11"/>
    <dbReference type="OMA" id="AVCTGHY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00144">
        <property type="entry name" value="tRNA_thiouridyl_MnmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="Adenine_a_hdrlase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="tRNA-specific_2-thiouridylase"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="137"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="7">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="359" mass="37961" checksum="55516D6F2847D6AD" modified="2010-04-20" version="1">MSGGVDSAVAAARAVADGHDVTGVHLALSSNPQTFRSGARGCCTLEDSRDARRAADVIGIPFYVWDMAERFREDVVDDFVAEYAAGRTPNPCLRCNEKIKFAAVLDRAVALGFDAVVTGHHARLADGVLRRSVDLGKDQSYVLAVLNAAQLSRAVFPLGDSTKDEVRAEAARRDLAVADKPDSHDICFIADGDTQGFLNQRLGSKTGDIVDAASGEVLGSHSGAHQFTIGQRHGLGIGRPAADGKPRYVLSITPVDNTVKVGPREALDVHVVHADRPVWLDGVEREGPFECQVQLRAHGEVHDATVTSDGDTITARLHSPAKGVAAGQALVVYQPDPEGDIVLASATIARTEALAPADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Y0</accession>
    <name>D3Q3Y0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019618.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4401"/>
    <dbReference type="EnsemblBacteria" id="ADD44047">
        <property type="protein sequence ID" value="ADD44047"/>
        <property type="gene ID" value="Snas_4401"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4401"/>
    <dbReference type="eggNOG" id="COG3655">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_31_8_11"/>
    <dbReference type="OMA" id="CRYLDCQ"/>
    <dbReference type="OrthoDB" id="2040098at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="76" mass="8266" checksum="25E8CE8F87BA8923" modified="2010-04-20" version="1">MDEPKRPEVRVTIDALLAERGMTATELARRVGITLANLSILKNGRAKAIRLSTLAAVCRELECQPGDILHLDTGPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Y2</accession>
    <name>D3Q3Y2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SpoOM family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4403</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019620.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4403"/>
    <dbReference type="EnsemblBacteria" id="ADD44049">
        <property type="protein sequence ID" value="ADD44049"/>
        <property type="gene ID" value="Snas_4403"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4403"/>
    <dbReference type="eggNOG" id="COG4326">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057336_0_0_11"/>
    <dbReference type="OMA" id="YQGTDWA"/>
    <dbReference type="OrthoDB" id="1033384at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009776">
        <property type="entry name" value="Spore_0_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40053">
        <property type="entry name" value="PTHR40053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07070">
        <property type="entry name" value="Spo0M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="256" mass="28038" checksum="7D177640AB7A7E26" modified="2010-04-20" version="1">MVFRKLKAAFGAGVSVDTVLTDSHVYPGGNLRGEVRFTGGGVDYNVQGITLEFNAVVEVESGDNEYKTTYDFHRAEVSGPFKLQEGAQHAIPFQIPVPWETPLSSIGGHHLHGMRLGVATELKLEGALDKGDIDPLVVEPLPIHGRVLDAVGQLGFAFHKADLEAGRIADSRMPFYQEIEYWAAGEFRRAFKALELTFVTNERDTKVILEVDRPGGFLTGGGDGYAVLRVPNGDTTDLTGPIRDQLMQLARRRGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q455</accession>
    <name>D3Q455_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Diguanylate cyclase with GAF sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_6322</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021511.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6322"/>
    <dbReference type="EnsemblBacteria" id="ADD45940">
        <property type="protein sequence ID" value="ADD45940"/>
        <property type="gene ID" value="Snas_6322"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6322"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021525_0_0_11"/>
    <dbReference type="OMA" id="PLGGPEC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048856" evidence="3">
        <location>
            <begin position="32"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="262"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="5">
        <location>
            <begin position="535"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="682" mass="70389" checksum="9580403AE66D89EB" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4A5</accession>
    <name>D3Q4A5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6374</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6374"/>
    <dbReference type="EnsemblBacteria" id="ADD45990">
        <property type="protein sequence ID" value="ADD45990"/>
        <property type="gene ID" value="Snas_6374"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6374"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_1_3_11"/>
    <dbReference type="OMA" id="DWIWGEQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="995"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="998"/>
            <end position="1020"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1042" mass="113809" checksum="21A16229355D831C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4I3</accession>
    <name>D3Q4I3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ADP-ribosylation/Crystallin J1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0426</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015714.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0426"/>
    <dbReference type="EnsemblBacteria" id="ADD40143">
        <property type="protein sequence ID" value="ADD40143"/>
        <property type="gene ID" value="Snas_0426"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0426"/>
    <dbReference type="eggNOG" id="COG1397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024566_5_0_11"/>
    <dbReference type="OMA" id="WHWTDDT"/>
    <dbReference type="OrthoDB" id="1661477at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005502">
        <property type="entry name" value="Ribosyl_crysJ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036705">
        <property type="entry name" value="Ribosyl_crysJ1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03747">
        <property type="entry name" value="ADP_ribosyl_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101478">
        <property type="entry name" value="SSF101478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="321" mass="33975" checksum="B016E49E719598D5" modified="2010-04-20" version="1">MESQRLSVDTATRDRRAAASLVGLSAGDAYGNQFFDLDAWRQIPCPGRLRQTPVYEPGHVESFLKAKLLPGGQWPWTDDSEMAFGIVAELRRNGEIDPDVLAATWASHYQLPRDYGLSALRILDGVSEGGDWRPLSRSAFDGAGSLGNGSAMRIAPLGAWFADDLDAVVTQARLASEITHSHVDGIAGGIATAMAAALSVRGSSDPGEFLEAILDVTPDGEVRHGIEEAAAHPAGTDPAEVAAHVGNGRYILATDTVPLCLWVAAHHLGDYPTAVRTVVSLGGDIDTNAAIVGGIVAAGDLREPVPGEWLAAREPYPHWFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5C5</accession>
    <name>D3Q5C5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4529"/>
    <dbReference type="EnsemblBacteria" id="ADD44174">
        <property type="protein sequence ID" value="ADD44174"/>
        <property type="gene ID" value="Snas_4529"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4529"/>
    <dbReference type="eggNOG" id="ENOG5031MNQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075797_1_0_11"/>
    <dbReference type="OMA" id="GRAKDFY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016566">
        <property type="entry name" value="UCP010219"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11361">
        <property type="entry name" value="DUF3159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="237" mass="25783" checksum="5CD580BB4042E3CF" modified="2010-04-20" version="1">MSEESRVRAGLVDDGGEPQPRPSAPRDDDDLPPMTEQVAQQLGGVRGLVESGIPVGVFVLINVIWEALYWAIGFAVGTAVAIAVLRLIRKESIRHAVNGLFGIALGAWLAWRSGDEGDFYWPGIIQGLAYAAVLMGSVAVRHPLVGWFWSIIAGGGKHAWREDRRLVRVFGWLTMLWGVVFLAKNLLRLWLRLGDMDTALGVVTLVGGYPVTGLLILISIAVVRKTHPGMTLKLKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5F0</accession>
    <name>D3Q5F0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021581.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6394"/>
    <dbReference type="EnsemblBacteria" id="ADD46010">
        <property type="protein sequence ID" value="ADD46010"/>
        <property type="gene ID" value="Snas_6394"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6394"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069610_0_0_11"/>
    <dbReference type="OMA" id="YEICATE"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="157"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD46010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="302" mass="33038" checksum="7FEEEF95164FB88D" modified="2010-04-20" version="1">MTDVTIRPADPDRDAAAIAALSTREFDFLLHNAATMRRNLDDSNPRKRKLSLVAEKDGELVAYAITSLDLESSVEGAATVNLIVAPEHRRTGIASALIEPLSAHWEAIGASTVTARLISEEAAAFAEKRGFKRSRTERISHVSLAGIPDVVAPAEGIVLKPLSELDDDRALYALDCAAMVDVPADEPWVPLPFDEWVEQYMADPRLDRHNTVLAFDGDTAVSVAWVERVGTRMWSGLTATLREYRGRGLAKAAKSAALHRARADGVVDAYTNNDATNAGMLAVNTWLGYRLHTEQYTHVHTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q649</accession>
    <name>D3Q649_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Xanthine/uracil/vitamin C permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2543</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017795.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2543"/>
    <dbReference type="EnsemblBacteria" id="ADD42224">
        <property type="protein sequence ID" value="ADD42224"/>
        <property type="gene ID" value="Snas_2543"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2543"/>
    <dbReference type="eggNOG" id="COG2252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024508_0_0_11"/>
    <dbReference type="OMA" id="WVLTNLP"/>
    <dbReference type="OrthoDB" id="558559at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904823">
        <property type="term" value="P:purine nucleobase transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="PTHR43337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="483" mass="49930" checksum="12539467729B3AFA" modified="2010-04-20" version="1">MSSSTTRAATRPKSGGEPGWFDRWFQITERGSSVGREVRGGLTTFMAMAYIIALNPLILSGAKDVNGESLSVVGVTTMTAFSAFVATLVMGALGRVPLALAAALTVNAVVAYQIAPQVTWPQAMGLVVIQGLVIVLLAASGVRTMIMNAIPLDLKHAIGVGLGLFIALIGLVNAGFVTRRPDADGTSVPVTLGQGGVLKGWPIVVFVVGMLIIIALWARKIPGSVLLGVVVATVLAIIIESTLHLGSKIWGVVTPAMPEKVAQAPDFSLFGQVDVIGAITQIGFVSLIVFVFTLVLSGFFDAMGTVIAVSDEAGLVDKDGQLPGIGRVLSIDGAAATFGGITSSSANTVFVESAAGVGDGARTGLASVVTGGMFGLAMFFAPLATVIPQQAAAPALVLVGGLMCAQAKNIDWKNTEIAIPAFLILAITPFTYSVTAGVGAGVIAYVVIKAVNGKWREPGWLLWIVSLVFVAYFGIHTIERLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q660</accession>
    <name>D3Q660_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2554"/>
    <dbReference type="EnsemblBacteria" id="ADD42235">
        <property type="protein sequence ID" value="ADD42235"/>
        <property type="gene ID" value="Snas_2554"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2554"/>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_612372_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="447" mass="45933" checksum="2191904DB4A40955" modified="2010-04-20" version="1">MAVTGDTPAAARRTDAKVHNAAADDLVDGVAGFAYHAAMTTPGVLVVDIGSSHTIAMIRRGDGTVETLLSDHSPPSLPATLAQVRDACARTMPEPPASVTITHPASWGPTKRLEVAEHARDAGLGAPTLLPAPVAATRYLVDVLGHALPVGATVFVADFDETGFAAAVLSHTPGGFAVLAADDARAPDATAMPVESAVRVGQAVLGSAGVPAERVATVMSIGAASRSPLATDTVQRVFGRPPFVVDQPELAAAHGALFDVHALPGPGAPPLIPVSGTPQPGPAAPMKPPRRLATVILGITAAFALVFVTVTAVANATIAAPADPESTADVKRDAGTAAEALLSYDHKDMDASITEAKSYTTEGFGREYVQNMEDLRPTAESEKASIEAEVVDIGIVENTGEAVEVLVFVNQTTTNSNIEGSRVDKSRVTLTMVLGHGGWKVDDMKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q674</accession>
    <name>D3Q674_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017820.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2569"/>
    <dbReference type="EnsemblBacteria" id="ADD42249">
        <property type="protein sequence ID" value="ADD42249"/>
        <property type="gene ID" value="Snas_2569"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2569"/>
    <dbReference type="eggNOG" id="COG1725">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_10_0_11"/>
    <dbReference type="OMA" id="INHLTVM"/>
    <dbReference type="OrthoDB" id="1860081at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="122" mass="13568" checksum="D26DC232E33AA809" modified="2010-04-20" version="1">MFDDRSPIYRQIAERIKGDILSGALAEDSQVMSTNEYAATYRINPATAAKGLRELLDEGILYKRRGIGMFVSPDARAKLREAHRSRFFTDVVDPMISEARTIGIPLDDVVGHIKAAETGENQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6D3</accession>
    <name>D3Q6D3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017879.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2630"/>
    <dbReference type="EnsemblBacteria" id="ADD42308">
        <property type="protein sequence ID" value="ADD42308"/>
        <property type="gene ID" value="Snas_2630"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2630"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_4_2_11"/>
    <dbReference type="OMA" id="CSFIAVR"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="10"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="159"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="309" mass="31836" checksum="DE68007FBC73973B" modified="2010-04-20" version="1">MRTDTTAANPYLLLMTTMMLWGGAFSSSKVVVDAVPHTVGAFLRFGGGALALLVVVRLYDRRQTPVPARKLWLGAAAGVLGVFAYNAFFFWGLSLAPSLDAGILIPVLSPVLTTAFLLVSGREKANRARVVGLSLGLVGAVIFFLGAGGATSAGPQRLPGDALFLLSAVCWAAYTLAGPRVMAGIAPLRATTYATCAGAVMLGALAVPDMATVDWTALPSLVWANVGYLAIGGAAVANLLYYRGVAAVGPARASLMMFSVPVVNTLCATLILGESLGWLQAAGACVLLTGAFLALTQGRLPGLRRPVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6E4</accession>
    <name>D3Q6E4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_4542</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0126 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019758.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4542"/>
    <dbReference type="EnsemblBacteria" id="ADD44187">
        <property type="protein sequence ID" value="ADD44187"/>
        <property type="gene ID" value="Snas_4542"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4542"/>
    <dbReference type="eggNOG" id="COG2860">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064906_1_1_11"/>
    <dbReference type="OMA" id="RAPRAWN"/>
    <dbReference type="OrthoDB" id="1665397at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="5"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="91"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="21229" checksum="6ABF6D351C99AE62" modified="2010-04-20" version="1">MFFLWLNLAGTIVFAASGAAAAVAKRLDLFGVVVVGVVTALGGGVFRDVVIGRIPPLAFTDWRYPTAAAVTAALVFWVHAQVFRLRRTMLTLDAAGLALFTVVGTTAALEAGVPWLGSCVIGTITGVGGGVLRDVLTAQIPAVLQREIYAVASMSGATVIVLANYFSLGTIWTSLAAAALVFGLRLLSSWRNWSAPVPKTPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6G4</accession>
    <name>D3Q6G4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4563</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4563"/>
    <dbReference type="EnsemblBacteria" id="ADD44207">
        <property type="protein sequence ID" value="ADD44207"/>
        <property type="gene ID" value="Snas_4563"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4563"/>
    <dbReference type="eggNOG" id="COG3386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024373_0_0_11"/>
    <dbReference type="OMA" id="CTVEDNR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048274" evidence="3">
        <location>
            <begin position="36"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="480" mass="50720" checksum="2CC9565303204E3D" modified="2010-04-20" version="1">MEHGQLTSDVRRWAAAITLAGLVAAAVALPAPAFAKDPKPGKKLCEVSDEALGELSGLVATDNGYAAIGDGSDGNVTTVDVIALDDNCASTGQNISGQVEPSDPEDLAVDGKGNYWVADTGDNDGARPSIALHKVTPDAQVSTYRFTYPDNAVDCEALLMQRDGTPIFATKELGVSNLYAPEGELDPNGAEAPLKKVGSVKIKATKTKGGPEEINGIPLGDAPSRFVTGGAVSPDGKKAVLRTYTDAYEWKVEGSDVAKSIKDGKPAITPLPEEPQGEAITYTTDGKKFVTGSEIGSGTAPALWSYTPAKAASGSDKKKDDEAAPEKSFLDTIIDTLGPNGILWAVAAVGVIGLIMVIIGGRVIWRARRNKANAHSLRESLDKDQQDGYERPRYRDQDDGFGGGKLFEPVSGHRQDGYQDDYYDEPRSGSVYGGHDDPRSGNVYGGHDDPRSGNVYGGGRPGRDRRDDEPNSGTVYGGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6T1</accession>
    <name>D3Q6T1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YibE/F family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0616</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015901.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0616"/>
    <dbReference type="EnsemblBacteria" id="ADD40330">
        <property type="protein sequence ID" value="ADD40330"/>
        <property type="gene ID" value="Snas_0616"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0616"/>
    <dbReference type="eggNOG" id="COG5438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028166_3_1_11"/>
    <dbReference type="OMA" id="SAVWELH"/>
    <dbReference type="OrthoDB" id="1746642at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012507">
        <property type="entry name" value="YibE_F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41771">
        <property type="entry name" value="PTHR41771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07907">
        <property type="entry name" value="YibE_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="436" mass="45124" checksum="54094F5DD469A682" modified="2010-04-20" version="1">MGTVHSHQTDEKNTPTTVRFALYLLVPVAVATAIAMALMWPTDKPEATSAAGAQEVTGTVTGISLKECPDTGTEPGGEPGDSGASAKPERCGTVTVELTSGADEGDIVTSTLPNGPGAPYVEVGDSVILMHLPEAEFSYSIIDQDRSTPLWILAIAFALAVIAFGRLRGLLSLVGLAVTFAVLLLFIVPAILSGESPLPVAIVGSCAIMLAVLYLTHGFRATTTIAVAGTLCSLVLTGLLSALAVGMAHLTGISDEDTSVLSMYHGVNTEGLLLAGILIGSLGALDDVTVTQASAVSELARANPEYGFGELYSAAARIGRSHIASVVNTIILAYAGAALPLLILIAAADRPLSETLTTQLIAEEIVRGIVGTIGLIAAVPLTTLLAALTVHKFAPPPGVELATPGPRPKRPRNEWLDMHEDETPPPESRPEAEEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Z6</accession>
    <name>D3Q6Z6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Snas_0682</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015966.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0682"/>
    <dbReference type="EnsemblBacteria" id="ADD40395">
        <property type="protein sequence ID" value="ADD40395"/>
        <property type="gene ID" value="Snas_0682"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0682"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_13_3_11"/>
    <dbReference type="OMA" id="WANDYLR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023834">
        <property type="entry name" value="T7SS_pept_S8A_mycosin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03921">
        <property type="entry name" value="T7SS_mycosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="13">
        <location>
            <begin position="12"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD40395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="349" mass="36047" checksum="5EBDB8D786BE2162" modified="2010-04-20" version="1">MDVGRVDALTKGEGVTVAVLDSGVSDKHRVLKGKVTAGGDYTEDRKGAGCDLIGHGTVIAGVIAGRPDPEGQFRGMAPEAELLSIRVRPDAEKTPGDGFSDVLAKAIDEAVDAKVDIINLSVATAPSAKLEAAVERAHDKGVLLVAAAGNQNGDGGRNEPVYPAAYGDGDRTDVSVLAVANLDTSGQPAEQSNTGSYVDVAAPGVDIIGPSPNSETEYSKGDSGTSYATPFVTGTAALVMARFPDLSPAEVAERITKTAEHPAGEDGRNDAVGHGMVDPYRAVTADLEKNTPHAQAPPPRPAWPGDTEYFARNAAGVMLLAAVVLVVAVAAGRSLIPRIRRNRELADRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q707</accession>
    <name>D3Q707_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Secretion protein snm4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0693</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EccD/Snm4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015977.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0693"/>
    <dbReference type="EnsemblBacteria" id="ADD40406">
        <property type="protein sequence ID" value="ADD40406"/>
        <property type="gene ID" value="Snas_0693"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0693"/>
    <dbReference type="eggNOG" id="ENOG502ZAY5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028325_1_0_11"/>
    <dbReference type="OMA" id="WPELEYD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044049">
        <property type="entry name" value="EccD_transm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006707">
        <property type="entry name" value="T7SS_EccD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024962">
        <property type="entry name" value="YukD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19053">
        <property type="entry name" value="EccD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08817">
        <property type="entry name" value="YukD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017804">
        <property type="entry name" value="Secretion_EccD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03920">
        <property type="entry name" value="T7SS_EccD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="442"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="EccD" evidence="5">
        <location>
            <begin position="97"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="473" mass="49372" checksum="2F4C02A51659EB2A" modified="2010-04-20" version="1">MTTAIRTGLTRITVSAPRRRIDLVLPDHLPVSELLPIILDYAGEGAADDAEKHGGFDLRRTDGKTINPAQSMAMQQIRDGELLHLAPRHADWPEGEYDDVVEAIAAGAKVLGKQWDGNHTRITGLTIAVIAGVLALAGLWLSGPKEVDLGSWLPAGITALSAAVVLMAIGIALARASGDSVAGATLGGLSLLFAAFGGYVILAFRYPLEFLGSEHLLVASAIVLSFSIVGFYAIGESLRVFTAGVVVGFFGIVAAALGFGPWNPDGDAAATVSITIMLLPSIPVLSMRFAKLPMPQLPQSAKELVKDSPNPPKEEIFAKVLRADELLTGLLIGVSVVTALCLWVVDTTPTLTAPVSQKILLGVIGCVYLLRARLFPAVRQRVPLLAAGIIGLALLADDAVGLFGPDLQLVGLGVIVLPAVLIAVASGLVYSKKAPSPYIGRIADILDILLIVAVVPVACAAMGLFGFFRGLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q777</accession>
    <name>D3Q777_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2671</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017919.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2671"/>
    <dbReference type="EnsemblBacteria" id="ADD42348">
        <property type="protein sequence ID" value="ADD42348"/>
        <property type="gene ID" value="Snas_2671"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2671"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="GYIWFAP"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="3">
        <location>
            <begin position="178"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="375" mass="40669" checksum="2C31D0F75D8E6181" modified="2010-04-20" version="1">MNAAPRSWWSSGSRWPAVLLDAALIAVAAADLWFNHMPGNWWDDILLVTGVLALALRRRFPLAVFIATLPMPLLTGQSAASLIALFTVACQTRSRWLLSGCALVYAGLTIAPWWGGDDILAESSWPVWGVYSLAPAGAAVFLGQLVQTKQELSKRLDEINEVREHEQALTTQKVLAQERAHLAREMHDVVSHQVSLIAVRAGALQVSAQEPVAREADTIRTLATRTLDELRYMVSVLRAGGGGDTSLAPQPTLDQLGKLVHNAGMETQLQTGPLPELNPPMQRAIYRTVQEALTNARKHAPGAAVRIHVTQDDGVVLTEVINAAPNRPVVPLPSAKHGLIGLKQRAELLGGTLEAGPTDERGWRVALRMPLKSMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7D6</accession>
    <name>D3Q7D6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycine dehydrogenase (aminomethyl-transferring)</fullName>
            <ecNumber evidence="2">1.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2731</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2731"/>
    <dbReference type="EnsemblBacteria" id="ADD42407">
        <property type="protein sequence ID" value="ADD42407"/>
        <property type="gene ID" value="Snas_2731"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2731"/>
    <dbReference type="eggNOG" id="COG1003">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004620_5_0_11"/>
    <dbReference type="OMA" id="MHINLHK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="PTHR11773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="6">
        <location>
            <begin position="192"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="532" mass="58386" checksum="F27649894B323818" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7N2</accession>
    <name>D3Q7N2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Erythromycin esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4732</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019945.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4732"/>
    <dbReference type="EnsemblBacteria" id="ADD44374">
        <property type="protein sequence ID" value="ADD44374"/>
        <property type="gene ID" value="Snas_4732"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4732"/>
    <dbReference type="eggNOG" id="COG2312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026490_2_1_11"/>
    <dbReference type="OMA" id="THRNAGG"/>
    <dbReference type="OrthoDB" id="1068352at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14728">
        <property type="entry name" value="Ere-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007815">
        <property type="entry name" value="Emycin_Estase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05139">
        <property type="entry name" value="Erythro_esteras"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="313" mass="34820" checksum="9FD6E86CE48B536F" modified="2010-04-20" version="1">MSDAVTNWIEHHAHRLTEFDPAAPLTDLKPLRAMIGGAKVVALGSSIRTSHELSALSHRILRLLVEFSGFRSLAFEGDDPHELGLDEYISTGTGDARALLSVARTFWQLEEVADLVEWMREHHRQHPDDAIRFARDLRRIPDSAPGPEDLAAIERDLADNITWWLEESTTKIVHWGGIAHTAVGDPRAVSPAPEPIEHRNAGAYLRERLGPDYVSVGLTFHHGLAPFEIPPPPEGFADHVLGQVAMDAYLLDLRQECPPSVESWLRSPTRTRLIGPAFDPGDHESFHMSGGSLKDWFDILIHVNEISPAQPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Q5</accession>
    <name>D3Q7Q5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019968.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4755"/>
    <dbReference type="EnsemblBacteria" id="ADD44397">
        <property type="protein sequence ID" value="ADD44397"/>
        <property type="gene ID" value="Snas_4755"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4755"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089258_4_1_11"/>
    <dbReference type="OMA" id="DTHKDYV"/>
    <dbReference type="OrthoDB" id="1706427at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="2">
        <location>
            <begin position="15"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="196" mass="21643" checksum="82E773581F6E044D" modified="2010-04-20" version="1">MAGRRTGPDLVALTVLAILSRGPRHAYDLHRFIVDTHKDYVTGLPRSLYHAVARLADDGHIAPVETSRAGRRPERTVYELTATGETELTHRLQTLLTTIGRDTTGFVAALSLMGGLPRETAASALRERAAALRTRVEGAKQTLADLTEHGVPRLPLLELEYEHSRYASELDWVERILADLHNGTIDWEVPLPPTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7V6</accession>
    <name>D3Q7V6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0749</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0749"/>
    <dbReference type="EnsemblBacteria" id="ADD40461">
        <property type="protein sequence ID" value="ADD40461"/>
        <property type="gene ID" value="Snas_0749"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0749"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_590389_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="463" mass="50788" checksum="DF2E172E4AA39EFE" modified="2010-04-20" version="1">MIPKAALRFASEHDGELLEAVRGGQAVPGAGGCVPRRRDRGLARYLDALAEGIVAANPPGAERQRALAQCLGTELLDGIIVRRWFDELPEAERAMLLDAATAFTRRWVSPQVFVRLEPAHRIMVHCLQSGDEDDLTDVVRYRAFGTPTRAIVDCGRVFAGLPLFRNPATDIPDACYEISATVGVEHRLSEYSWHGTRMRLSGYAFINHVDTDDQATTVVLRERSSGEEAAVPARLRPSPELSSQFHDGLYEYGYAGFDAVVDLDALPGDRALPDGQWDVLVEVRAHGVERRCRVATLPDGDRDPRVDHHLPDFSRRGAGLVTTYVSHEGQLTLFVETYGGASPDLVQLTCCESSGVGLTLSAYSGISDWPVGTTARLCLVRGDVTRTFPAAMRPCGAGFGLTAHIRASKLLLPPGWWGVGLRLTWEHGSWEVPLHDAEGRPVWLRGRRSAREMLGLVRDVVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Z2</accession>
    <name>D3Q7Z2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Daunorubicin resistance ABC transporter ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0785</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016068.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0785"/>
    <dbReference type="EnsemblBacteria" id="ADD40497">
        <property type="protein sequence ID" value="ADD40497"/>
        <property type="gene ID" value="Snas_0785"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0785"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="SHDMYEV"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043215">
        <property type="term" value="P:daunorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900753">
        <property type="term" value="P:doxorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005894">
        <property type="entry name" value="DrrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01188">
        <property type="entry name" value="drrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="3"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="324" mass="35675" checksum="BA220D4E9C97CC59" modified="2010-04-20" version="1">MLIETAGLRKTFRNRQKKEVVEAVRGVDLAVKEGEIFGFLGPNGAGKTTTLRMLSTLLEPSGGTAVVAGFDLRKQPVKVRRAIGYVGQSGGTWGEVSAREELVMQGKLYEMPKSECKTRAQEVIEAFEMTEFADRKCKTYSGGQRRRLDVALGTVHRPKLLFLDEPTTGLDPQSRAHMWDEVRKLRERGTSIFLTTHYLDEADALCDRLAIIDHGEIVTEGTPLALKRQIAGDIVAIGVNGDATRARELLDAKEFVREVEAGEPDQATGSVTLRLFVEDGSAAVPEILRTLDAADIAPSSIELHRPSLDDVFLKQTGRSLREND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q817</accession>
    <name>D3Q817_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016093.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0810"/>
    <dbReference type="EnsemblBacteria" id="ADD40522">
        <property type="protein sequence ID" value="ADD40522"/>
        <property type="gene ID" value="Snas_0810"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0810"/>
    <dbReference type="eggNOG" id="COG1942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148073_0_1_11"/>
    <dbReference type="OMA" id="ESATENW"/>
    <dbReference type="OrthoDB" id="2013680at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037479">
        <property type="entry name" value="Tauto_MSAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38460">
        <property type="entry name" value="PTHR38460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14552">
        <property type="entry name" value="Tautomerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="SSF55331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="131" mass="14782" checksum="5551DEF3DA3B723E" modified="2010-04-20" version="1">MPTTLVEVRRQYSQAEEVGIIDAVHDALVSAFEIPVEDRNVRLIVHEPHRFACSPRHTLPEFYTLVSVDCFAGRSVRAKRKLYTEIVDRLAPFGIPRDHVTINLRESPTENWGYAGGKAACDMDLGFDVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8E1</accession>
    <name>D3Q8E1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018086.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2839"/>
    <dbReference type="EnsemblBacteria" id="ADD42515">
        <property type="protein sequence ID" value="ADD42515"/>
        <property type="gene ID" value="Snas_2839"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2839"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_839144_0_0_11"/>
    <dbReference type="OrthoDB" id="385673at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048309" evidence="1">
        <location>
            <begin position="26"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="331" mass="35655" checksum="D1F5B349836D0EB4" modified="2010-04-20" version="1">MSKPGRIKILSLVGAVVLAASVGCAKGSGEDKSADGGKEDQQKFTTGKYFDYLFYLDRAEDGAVKLQRWNGDPDAKPETLVEGEGLMYETLNVSKYGNFVSWVEKRGGGTKLMVHYVESGKTKETLDYPVDDDVCVTPTWAADGRGQLLVPADDFKTVRSYDVPSTSKSDPKPIAGCDPLQAAGEGDAPDIFYWNAERGDVEFVTPQGEVAKTGVGAAVEKELGTDVHGLYAVSMDGSEVCLRLKDDQDDAGRALSCDVAVDVATHDVTLRPDEELQIQYLDGPAVERVGGELRFVPDITDRKGDPMMLDEPKALADTDLIAASVVHHTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8F1</accession>
    <name>D3Q8F1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2850</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018096.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2850"/>
    <dbReference type="EnsemblBacteria" id="ADD42525">
        <property type="protein sequence ID" value="ADD42525"/>
        <property type="gene ID" value="Snas_2850"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2850"/>
    <dbReference type="eggNOG" id="COG0410">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="YVMGHGQ"/>
    <dbReference type="OrthoDB" id="1475841at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="10"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="250" mass="26376" checksum="4CA7D4C1CBC9C5D3" modified="2010-04-20" version="1">MTQLDFPLALSLSGVSSGYNGGRALHAVSLEVAEGSVHAIVGHNGAGKTTLMSTVAGELAVAEGRIWFDGKDISRTAPHRRAKRGIGYVPQGRRVFKSITVAEHLAIAHRDRKSEWNPARVIDLFPRLGERMKHKGAQLSGGEQQMLAIARALLTSPRLLLLDEPTEGLAPAIVEQIRGTLGKLAAEGMTILLAAPQPEWPIAIADHISVLSAGKLTASIPGSEARDDASSLLEALTITAGSKPEEEPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8T0</accession>
    <name>D3Q8T0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4881"/>
    <dbReference type="EnsemblBacteria" id="ADD44522">
        <property type="protein sequence ID" value="ADD44522"/>
        <property type="gene ID" value="Snas_4881"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4881"/>
    <dbReference type="eggNOG" id="COG3239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016265_1_0_11"/>
    <dbReference type="OMA" id="MITFYIR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="PTHR19353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015921">
        <property type="entry name" value="FA_sphinglp_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="2">
        <location>
            <begin position="60"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="346" mass="38524" checksum="3EE417A226E07BFE" modified="2010-04-20" version="1">MSANALSPVGEKTSRYPQLAKQIRDAGLLRRRPWYYAWRISATVAAYAAAWAVFVLVGDSWWQLFTAAAMAVTFMQFGFLGHDAGHQQIFGSRRGNSIVGYLLGNLGLGLSFGWWSDKHTRHHANPNVEGRDPDLNVDPVAFTDAQAARSRGIGKQIVRFQAALFIPLLFLEAFHMHFNSLRRIVNRNRPIRARGLEAVLFTVHVVAYLGIVFTVLSPGTAVVFIFVHQGLLGVYMGASFAPNHKGMPVLTDGEQADFLLRQVLTARNIDGGRFVDAALGGLNYQIEHHLFPHMPRPNLRQAQPVVRQFCAEHDIAYCQTSMFGSWGRVLGHLHDMGRDIRNPGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8T5</accession>
    <name>D3Q8T5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CO dehydrogenase maturation factor-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020098.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4886"/>
    <dbReference type="EnsemblBacteria" id="ADD44527">
        <property type="protein sequence ID" value="ADD44527"/>
        <property type="gene ID" value="Snas_4886"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4886"/>
    <dbReference type="eggNOG" id="COG3640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_852393_0_0_11"/>
    <dbReference type="OMA" id="GCVCPAS"/>
    <dbReference type="OrthoDB" id="1631847at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="1">
        <location>
            <begin position="7"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="35130" checksum="334F9A5A42269D7A" modified="2010-04-20" version="1">MKIAFVGKGGSGKTTLASLFARRAVAAGHPVFAIDADINQHLAAALGVDEDTAAKLPKLGDHLAEIKEYLRGDNPRIASAEAMVKTTPPGSGSRLLTIGEDNPVYDACVRNLAGLRLAVTGGFAEDDLGVACYHSKVGAVELMLNHLVDGPGEYVIVDMVAGAEAFASGLFTRFDRTFLVCEPTVRSVGVYKQYAEYAADYDVAISVIGNKIDEPEDVDFLREHVGDALFGWCGRSKFVKAAERGSVGPIADLEPENLALLDRARELVELGGKDWARFSEQARLFHRRNAEAWGNSRMGVDLSEQIDPDFVLGPDSTTDTRGMAKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8V8</accession>
    <name>D3Q8V8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4909</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020121.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4909"/>
    <dbReference type="EnsemblBacteria" id="ADD44550">
        <property type="protein sequence ID" value="ADD44550"/>
        <property type="gene ID" value="Snas_4909"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4909"/>
    <dbReference type="eggNOG" id="COG1408">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025443_5_0_11"/>
    <dbReference type="OMA" id="YWLAWPG"/>
    <dbReference type="OrthoDB" id="1690667at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="168"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="388" mass="42158" checksum="AAA176455736E5CE" modified="2010-04-20" version="1">MEIPFWVWPQSVAWVLVHGYLWWRLVRCAMPPGRWRKAATIALAVMAPTVPGALIAMHTLSPTEGAWITWPGFIWYGLLVYLLLALVAGELLRLVLFVARKIRRRGAEPETPEAVASRRRFLARGVAIGAGAVAVTTVGYGMTQAFSSARLERITIRLRGLADAGEGFRIALVADTHVGPFLGRGNISGIVERVNAEKPDVVVIPGDLIDGTVADLGPAVAPLGDLRARHGVYFSLGNHEYLFDFDNWVEYLRDLGIRTLRNERVELPHFDLAGVNDSSGDNVGDPPDYERALGDRDPDRPVVLLAHQPAQAYEAQKYGVDLQLSGHTHGGQFFPAGLLTSIGQPVMAGHGTVGDTQLYVTRGTGFWGPAIRVGSPPEITLITLAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q901</accession>
    <name>D3Q901_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0899</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0899"/>
    <dbReference type="EnsemblBacteria" id="ADD40610">
        <property type="protein sequence ID" value="ADD40610"/>
        <property type="gene ID" value="Snas_0899"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0899"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="MERPLEW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="689"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="810"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="210"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="898"/>
            <end position="919"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="919" mass="100979" checksum="CA0747EB2FF136EF" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q988</accession>
    <name>D3Q988_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018141.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2895"/>
    <dbReference type="EnsemblBacteria" id="ADD42570">
        <property type="protein sequence ID" value="ADD42570"/>
        <property type="gene ID" value="Snas_2895"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2895"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_18_2_11"/>
    <dbReference type="OMA" id="QTWREAY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="192" mass="21374" checksum="02CD2A3153567DD6" modified="2010-04-20" version="1">MPVRVATTMDAAAIQRVRVDSWRAGYAGVVPAPVLASMSTEVPEHLTRRLAEPPPSCALYVDELDGDIRGFVNCGPYRHDQDATRRDPSQGGEIYAIYVAPTHWGGGAGQALMTQALTHLEHENLNPVRLWVLADNPRARRFYERGGFTLDGAASPYIFDDGTTLTEVRYRRDQPLSNHWELVQDSCKVQEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9C7</accession>
    <name>D3Q9C7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4440 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018180.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2934"/>
    <dbReference type="EnsemblBacteria" id="ADD42609">
        <property type="protein sequence ID" value="ADD42609"/>
        <property type="gene ID" value="Snas_2934"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2934"/>
    <dbReference type="eggNOG" id="COG4319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129336_2_0_11"/>
    <dbReference type="OMA" id="AMHRDET"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027843">
        <property type="entry name" value="DUF4440"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011944">
        <property type="entry name" value="Steroid_delta5-4_isomerase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14534">
        <property type="entry name" value="DUF4440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02246">
        <property type="entry name" value="TIGR02246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4440" evidence="1">
        <location>
            <begin position="5"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="133" mass="14766" checksum="32C6001AE8E3446E" modified="2010-04-20" version="1">MNTEIEAIHRTFAEYQEHQTEPEPFLAMHRDETIVVNIAGRRVLGKEALAQAMTAALASPLAQVRTTLDIEDVRFVREDVALVSAIKNVHDERDEKDEADAGFPSTGALTLLLSKEEGQWRVALAQTTPRLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9I4</accession>
    <name>D3Q9I4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018237.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2992"/>
    <dbReference type="EnsemblBacteria" id="ADD42666">
        <property type="protein sequence ID" value="ADD42666"/>
        <property type="gene ID" value="Snas_2992"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2992"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4978">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065103_2_2_11"/>
    <dbReference type="OMA" id="HYDKEEI"/>
    <dbReference type="OrthoDB" id="1748122at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="282" mass="30615" checksum="C4040BEA911C479C" modified="2010-04-20" version="1">MFTIGDFARHGRVSVRMLRHYDAIGLLSPAHVDRSTGYRYYRAEQLSRLNRLVALKDLGFTLRQVGSILDEDITVAELRAMLRLRRTELEETIATARSGLLQVEARLHSIEKEDSMPDEDIIVKKLPAVDLAELSAPADSFSPHHIGPVVDGLFDQLRARLAAAGVSATGPDTVYFETPDQLGEQIIVHAGLPVATGTAAEDFDVTTLPPVETAATVLFPGLGNGFLAISQQLVRWVDTHGYRFDGLARQISFGSSTDTAEQVAELQAPIVRTCGTPGGPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9U8</accession>
    <name>D3Q9U8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5007</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5007"/>
    <dbReference type="EnsemblBacteria" id="ADD44644">
        <property type="protein sequence ID" value="ADD44644"/>
        <property type="gene ID" value="Snas_5007"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5007"/>
    <dbReference type="HOGENOM" id="CLU_1569738_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048981" evidence="2">
        <location>
            <begin position="34"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="170" mass="17262" checksum="564F5EDFB4F70361" modified="2010-04-20" version="1">MSLLSHRRALVLAGLTGMLLAGGTLATATAAQANDTSPTDNTKLAPIPSATLDIAEAADKAEAKYPDCEATAALFYDTANTPIWDVELTCASGTIKYVTVDANSGTVADNGSTTDDTTDSTNPTDPTDPSDSTKSDKSEAPGSDKKNPSDNNSSASDSGDARGTGKNADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Y8</accession>
    <name>D3Q9Y8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Secretion protein snm4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0990</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EccD/Snm4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016271.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0990"/>
    <dbReference type="EnsemblBacteria" id="ADD40700">
        <property type="protein sequence ID" value="ADD40700"/>
        <property type="gene ID" value="Snas_0990"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0990"/>
    <dbReference type="eggNOG" id="ENOG502ZAY5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028325_1_0_11"/>
    <dbReference type="OMA" id="FKLAGMR"/>
    <dbReference type="OrthoDB" id="1786282at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044049">
        <property type="entry name" value="EccD_transm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006707">
        <property type="entry name" value="T7SS_EccD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024962">
        <property type="entry name" value="YukD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19053">
        <property type="entry name" value="EccD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08817">
        <property type="entry name" value="YukD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017804">
        <property type="entry name" value="Secretion_EccD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03920">
        <property type="entry name" value="T7SS_EccD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="441"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="EccD" evidence="5">
        <location>
            <begin position="100"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="470" mass="48913" checksum="977B0B67F942D752" modified="2010-04-20" version="1">MATTDTALCRVTIVAPHTRMDVALPAQVPLVELQTELLVHAASGPDGEYFVDDGIGVGGWALARLGEPALDAELSCAELGIIDGEELFFRPVEDAVPGIIFDDVVDAVSVAGVRRSGVWDSDASRKFGLAAAAAALLGAIGVAGYVGTVLAGTLVLIAGVVSLAAAWALERAFERTRPATLLGAMGVACGLFGGIILLSQERPLEDLGAPQFLAGGSVMAIFALLASLAVERAMPLFHSVILAGIGLILATATCTWLPVEQPAAAATLAAIFLLVIPALPMLSYRLAQLPIPEVPSSTDELRRETPPPDDAASDLALVRSDRADEFMSGLLTACSVVVGGCAMVLGLTVTGQVLPSLIMSGLFSAWLLLKSRYFRSIGQRLPLLIGGFLGPAALAYTGATALGPNARLLVVGASLTVLTILLLVHALAITGRKISPVWGRVGDVVQMLIGVAMVPMTLWVWGAYWWIRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAD9</accession>
    <name>D3QAD9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018293.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3051"/>
    <dbReference type="EnsemblBacteria" id="ADD42722">
        <property type="protein sequence ID" value="ADD42722"/>
        <property type="gene ID" value="Snas_3051"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3051"/>
    <dbReference type="eggNOG" id="ENOG50331K6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110740_1_1_11"/>
    <dbReference type="OMA" id="TFRPTRT"/>
    <dbReference type="OrthoDB" id="1801166at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019692">
        <property type="entry name" value="DUF2581"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10756">
        <property type="entry name" value="bPH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="152" mass="16148" checksum="16B4B2D48219A19F" modified="2010-04-20" version="1">MNKTAGSGVELVASPRKTTIACWIGAVLVLAVCVVAATAMGGKTEGGGVFHSADAYAMVGLGVLAALGILTFARPRVWADEHKVRVRNLFGSTEVPWQIVESVRFPRGASWAMLELADDDVIAVMAIQSVDKDRAVAAVRRLRELLAESRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAM4</accession>
    <name>D3QAM4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proton_antipo_M domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3136</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018378.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3136"/>
    <dbReference type="EnsemblBacteria" id="ADD42807">
        <property type="protein sequence ID" value="ADD42807"/>
        <property type="gene ID" value="Snas_3136"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3136"/>
    <dbReference type="eggNOG" id="COG0651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_632997_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="360"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="404"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="3">
        <location>
            <begin position="181"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="433" mass="44229" checksum="2A576F0FC69255F1" modified="2010-04-20" version="1">MPLYLALAVPAIVAAVYVYFGWTRRTRWLATMAAASILVSGLWLRASPQVDEALGGWLIATPETALLLIIVGLAATLTMAGFPAQLANEIKDHVIGPVTARGYGVFATTALPFAVIAATAAVPVISLVAIQIMVVLIAGMVAARRKPAQLRAAYGYGLACTAGLALVALGSLIPAGVTPMILVAAGWAALAGLAPLHWWLPPTVSVASAPVSALIVGVQAPLAWAMLLRLEGPTQRLLIVAAPVSIMVAIVGLIRQRDLRRLVAYVGIAGSGLLAWALATTPEPSSLRMVLSLSLNAVLLYLAVGHVVSLTGSGRIAMVRGQWTRAPLLGGALGLGLLAATVLMPYLAVRPLAALAPTPAGILGLACGIGMILVAIAAAIPTWRMLAGDPADRLDVTTGPARPLGSAGPVLIVATVLALLTPLAAGAISTDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAM8</accession>
    <name>D3QAM8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Threonine aldolase</fullName>
            <ecNumber evidence="6">4.1.2.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5037</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.5" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020245.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5037"/>
    <dbReference type="EnsemblBacteria" id="ADD44674">
        <property type="protein sequence ID" value="ADD44674"/>
        <property type="gene ID" value="Snas_5037"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5037"/>
    <dbReference type="eggNOG" id="COG2008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029381_0_4_11"/>
    <dbReference type="OMA" id="NKGGGAC"/>
    <dbReference type="OrthoDB" id="1124266at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004793">
        <property type="term" value="F:threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="PTHR48097:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="5">
        <location>
            <begin position="4"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="337" mass="35690" checksum="7237283F16B102C7" modified="2010-04-20" version="1">MTVDLRSDTVTKPTPGMREAMATAEVGDDVYGEDPTVTALETEVAALLGKEAALFVPSGSMGNQIALQLLVSPGEELLADSDAHIVSHEVGAAAAIGGISTRTWPTRGGHLDVGVVEEFIRTGVGYHTVNTAAIAVENTHNRGGGTALPLYKLEKLRTVADERGLKLHLDGARLWHAHVKDGVPLARYGTLFDTVSVCLSKGLGAPVGSLVVADAEGIERARVLRKRMGGGMRQAGILAAAGRYALTHHLARLKDDHARAHRLAAALEPFGVTDLSRVQTNIILLRIPRIADFAAAAADKGVMVSVMSKDQGRLLTHLDVDDDGLDHAIKVLTDLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBB6</accession>
    <name>D3QBB6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphotransferase system, phosphocarrier protein HPr</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1223"/>
    <dbReference type="EnsemblBacteria" id="ADD40933">
        <property type="protein sequence ID" value="ADD40933"/>
        <property type="gene ID" value="Snas_1223"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1223"/>
    <dbReference type="eggNOG" id="COG1925">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136230_3_2_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPr" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="93" mass="9667" checksum="291D966BE180E929" modified="2010-04-20" version="1">MSERRVKVACDGGLNDGNAVKLVQLAARAEAPVTISRDDAEPVAANHAVSVLALEIGEGEEVILASEDEAALDKLTELISCLAVVAAVWCARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBP2</accession>
    <name>D3QBP2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11 12">Xylose isomerase</fullName>
            <ecNumber evidence="4 11 12">5.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">xylA</name>
        <name evidence="15" type="ordered locus">Snas_3254</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11 12">
            <text>alpha-D-xylose = alpha-D-xylulofuranose</text>
            <dbReference type="Rhea" id="RHEA:22816"/>
            <dbReference type="ChEBI" id="CHEBI:28518"/>
            <dbReference type="ChEBI" id="CHEBI:188998"/>
            <dbReference type="EC" id="5.3.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11 13">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the xylose isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.5" evidence="4 11 12"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018495.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3254"/>
    <dbReference type="EnsemblBacteria" id="ADD42924">
        <property type="protein sequence ID" value="ADD42924"/>
        <property type="gene ID" value="Snas_3254"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3254"/>
    <dbReference type="eggNOG" id="COG2115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060750_0_0_11"/>
    <dbReference type="OMA" id="HKFTFGL"/>
    <dbReference type="OrthoDB" id="481478at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009045">
        <property type="term" value="F:xylose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00455">
        <property type="entry name" value="Xylose_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013453">
        <property type="entry name" value="XylA_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001998">
        <property type="entry name" value="Xylose_isomerase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00688">
        <property type="entry name" value="XYLOSISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02631">
        <property type="entry name" value="xylA_Arthro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51415">
        <property type="entry name" value="XYLOSE_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="14">
        <location>
            <begin position="43"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD42924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="390" mass="42765" checksum="17D67BC1082E08B0" modified="2010-04-20" version="1">MSDKYTPVPDDKFSFGIWTVGWAAQDVFGPATRAPMPADRAVHKLAEIGAYGVNFHDNDVFDFDDPETVRDAKIAAFRKALDATGLKVTTATTNLFSHPIFKDGAFTHNDRDVRRFALAKVMRNLDLAAELGAGVYVCWGGREGAESGGAKNIQAALDRMKEAFDILGAYVTDQGYDTRFAIEPKPNEPRGHILLPTVGHALAFINELEYSDRVGVNPEIGHEEMAGLDYAAGIRQALWHGKLFHIDLNGQTGPRYDQDLRFGAGNVGGAFWAVDAIEEGIANGQYSGPIHFDFKPPRTEDDDGVWVAAAACMRNYKILRDKVHTFRSDPRVREALEAARVDQLTVPTLAKGETWASIKDLTVDVAGLAARGMAFERLDQLALEHLYGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU06</accession>
    <name>D3PU06_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phenylacetate-CoA oxygenase/reductase, PaaK subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1242</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016523.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1242"/>
    <dbReference type="EnsemblBacteria" id="ADD40952">
        <property type="protein sequence ID" value="ADD40952"/>
        <property type="gene ID" value="Snas_1242"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1242"/>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_14_1_11"/>
    <dbReference type="OMA" id="FLCGPFE"/>
    <dbReference type="OrthoDB" id="1885467at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011884">
        <property type="entry name" value="PA_CoA_Oase5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02160">
        <property type="entry name" value="PA_CoA_Oxy5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="13"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="5">
        <location>
            <begin position="277"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="366" mass="40351" checksum="C33010DE2406DE04" modified="2010-04-20" version="1">MSVVLSRPKRRRPQWHKLRVADVERLTDEAVTVAFEVPEDLRETFDFTPGQHLTLRRFDDGEEVRRSYSICSTPSHLRSSGVVRVGIKKIAKGSFSGYATTSMRPGDVVELLPPLGTFTTQLDPARSRHYAGIVAGSGITPVMSIAASALETEPESRVTLVYGNRSAATVMFADAIADLKDRFPDRFQLIHVLSREPQAAELLSGRLDEDRLGRIFASLLPIDTVDDWFLCGPYGMVIGAQKVLSEAGVTDDHIHHELFYAEEIPDEPEQAPVEGETALTVTLDGRASTVTMRRDERVLDAALRVRPELPYACKGGVCATCRAKLLDGDVHMARNYALEQSDVDNGYVLTCQSTPTTDEVAVDYDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU71</accession>
    <name>D3PU71_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein tyrosine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1308</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016588.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1308"/>
    <dbReference type="EnsemblBacteria" id="ADD41017">
        <property type="protein sequence ID" value="ADD41017"/>
        <property type="gene ID" value="Snas_1308"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1308"/>
    <dbReference type="eggNOG" id="COG0394">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071415_1_0_11"/>
    <dbReference type="OMA" id="LDDPWGR"/>
    <dbReference type="OrthoDB" id="2062716at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="3">
        <location>
            <begin position="4"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="192" mass="20896" checksum="2878B6176BDE617C" modified="2010-04-20" version="1">MPPFTVLHVCMGNICRSPMAERLLTLRVNQIAGDEDLVYSHSCGIGLWHVGERMNPPAARELRSRGGTDAGFKAQHIARDLVEASDVILTATDEQYEYIAETFPDALPRTFLLRHFGRLAAGIDPNELPVSDGSAAAVHARGVALVAAADRRRDSQDAENLDDPWGESPAIFRRIGDEIDEALKPVVAALLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU97</accession>
    <name>D3PU97_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyridine nucleotide-disulfide oxidoreductase dimerization region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1334</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="2">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016614.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1334"/>
    <dbReference type="EnsemblBacteria" id="ADD41043">
        <property type="protein sequence ID" value="ADD41043"/>
        <property type="gene ID" value="Snas_1334"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1334"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016755_1_3_11"/>
    <dbReference type="OMA" id="MMIRAAN"/>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="6"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="4">
        <location>
            <begin position="339"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="177"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="3">
        <location>
            <begin position="42"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="452" mass="47382" checksum="E87DD4F2AE059EA0" modified="2010-04-20" version="1">MVKQVDVIVIGMGVGGEAVAESLAGEGLSVVGIEGRLVGGECPYWGCIPSKMMIRAADLIAETRRVDGIAGTATVTPDWSPVAIRIRDEATTNWDDAIAVKRFTDAGGEFVRGWAKLTGPGQVEVDGQAFEADKGVVIGTGTTPVIPPIDGLADTPYWTNRDAVETTTVPDSMIVLGGGAIGLELAQAFSRFGANVTVVEAADRLLPPEEPESSALARQALEADGITVHTGSRAERVEHDGHTFTVATADGKSLTAEKLLVAVGRRVDLSTLGVDTLGLDPKARNLTVDEFMRAGEKLWAVGDVTGHGAFTHVATYQADIAVADILGRSTPGADYRALPRVTFTDPEIGAVGLTESQAREQGLEVATASAQIPSTARGWIHKAGNEGFIKLVVDTEREVLVGATSAGPNGGEVLGALTVAVHGEVPIGRLKHMIYAYPTFHRGIQDALRELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUG4</accession>
    <name>D3PUG4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3311"/>
    <dbReference type="EnsemblBacteria" id="ADD42977">
        <property type="protein sequence ID" value="ADD42977"/>
        <property type="gene ID" value="Snas_3311"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3311"/>
    <dbReference type="HOGENOM" id="CLU_3205538_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="45" mass="4708" checksum="18194FEE3C05FF56" modified="2010-04-20" version="1">MISRIDGGNPTNVTAPGCGKRHGHNVQTGFVKSGEINNLTNGAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUG7</accession>
    <name>D3PUG7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3314</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018551.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3314"/>
    <dbReference type="EnsemblBacteria" id="ADD42980">
        <property type="protein sequence ID" value="ADD42980"/>
        <property type="gene ID" value="Snas_3314"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3314"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_11"/>
    <dbReference type="OMA" id="HIVGCAG"/>
    <dbReference type="OrthoDB" id="1209997at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="267" mass="27656" checksum="EAFC4F57C722AEB9" modified="2010-04-20" version="1">MLLNGKNAVVYGAGGAVGSAVARAFAREGARVFLTGRTLKPLEALATELRDSGAQAEAARVDALDEDAVDAHAEQVVSSAGSLDVSFNGVGIDNGDQGVPLVEISADVFGTPIRDYTRTHFITARAAALRMMKQKSGVILPLSGPMARSAAAFSGSFGLAHAAIESLSRQLAAELGPHGIRVVCIRPTGMRETAEQLGSHVGQVWQRAAERLGLPFEELLTMVSSGSPLERALAVNEVAEVAAFMASDRASAMTATTANVTLGSVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUL3</accession>
    <name>D3PUL3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Abortive infection protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018597.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3361"/>
    <dbReference type="EnsemblBacteria" id="ADD43026">
        <property type="protein sequence ID" value="ADD43026"/>
        <property type="gene ID" value="Snas_3361"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3361"/>
    <dbReference type="eggNOG" id="COG1266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051806_4_1_11"/>
    <dbReference type="OMA" id="ICAWHSI"/>
    <dbReference type="OrthoDB" id="1623593at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="278" mass="29325" checksum="CEC6E33492BF96D9" modified="2010-04-20" version="1">MRLLKQLVAIAAVSFLGGQAVYAVSDNKLLTLFVGLAVAVAALATYAWVVRWSERRKPVAELAANRAAAGIGWGTLIGAGLFALVIFNIAFLEGYHVNGRGSIESAVALFGFMAAAAVTEELLWRGVLFRIVEQRIGTWIALTLTGLAFGLVHLVNPNANLWGAIAIAIEAGGMLTAAYVATRSLWLPIGLHFGWNFAASGIFSTEVSGNGTPQGLLDASTSGPVILTGGDFGPEGSLYSVVFCVLATVVFLWLARRRGNLVPLRRSARAEAPATLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUT8</accession>
    <name>D3PUT8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Poly (3-hydroxybutyrate) depolymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020533.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5328"/>
    <dbReference type="EnsemblBacteria" id="ADD44962">
        <property type="protein sequence ID" value="ADD44962"/>
        <property type="gene ID" value="Snas_5328"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5328"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042524_0_0_11"/>
    <dbReference type="OMA" id="KGCFDWW"/>
    <dbReference type="OrthoDB" id="1152816at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048596" evidence="2">
        <location>
            <begin position="23"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="317" mass="33612" checksum="AA2728448F99AD51" modified="2010-04-20" version="1">MIPLVLALTATLVPAATPDTDATPADVYVVGISSGGYMADQLHMAHSSTFDGLGIFSAGPYHCARGNLTTAQLACMNDLQDNDPGALQQLARDRAAEGTIDPVDNLTTNPVWIYHGRNDSTVKQSVNDDLASFYTDFGANVSYRNDSPAGHAWVSPLGPNACETTAAPYINNCGDDPQSAMLTHLLGPITAPAPQLSGDLTTFDQNPHAPGGNAATISMGPTGYRYTPSTCTNGDCRLLVALHGCKQSATTIGTTFVENAYLNEYADTNNTVVLYPQATPSTDNPNGCWNWWGYGNDPNYDTHEGQQIQAIMSMVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV90</accession>
    <name>D3PV90_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_1437</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016714.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1437"/>
    <dbReference type="EnsemblBacteria" id="ADD41143">
        <property type="protein sequence ID" value="ADD41143"/>
        <property type="gene ID" value="Snas_1437"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1437"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_113_1_11"/>
    <dbReference type="OMA" id="LWATAFQ"/>
    <dbReference type="OrthoDB" id="1293707at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038318">
        <property type="entry name" value="KdpD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025201">
        <property type="entry name" value="KdpD_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003852">
        <property type="entry name" value="Sig_transdc_His_kinase_KdpD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13493">
        <property type="entry name" value="DUF4118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02702">
        <property type="entry name" value="KdpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="627"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD41143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="854" mass="91132" checksum="FC4EF1D02C38DC06" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVG0</accession>
    <name>D3PVG0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018645.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3410"/>
    <dbReference type="EnsemblBacteria" id="ADD43074">
        <property type="protein sequence ID" value="ADD43074"/>
        <property type="gene ID" value="Snas_3410"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3410"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_8_4_11"/>
    <dbReference type="OMA" id="SKHRIEH"/>
    <dbReference type="OrthoDB" id="1616572at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="295" mass="31937" checksum="86F5E16D6E4424AA" modified="2010-04-20" version="1">MTRVLVAGATGRQGGAVVDRLRQRGHEPVAYVRDPDSDAAKALARDGVRLATGDLADAEALTRAAKGADAIFGLTVPFGENGTEEEIAQGRALADAAAAVDAHLVYSSVKGANGDVDVTVEHASAKQIVHRYLVSQGLRFTGIQPSYFMENALNVGFTRLNQGVYAFPLTADRKLDQVTTLDIAGMAVHAIENAEALNGRAIDVVSETLTSVEVAAVLSEVIGKDLPYEQIPIPMIRQWAGDETAELFQRFEDNREHTDVAALRAEFPDIGWHSYRDWAKTVDWDQVLAQKPEWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVQ1</accession>
    <name>D3PVQ1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3502</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3502"/>
    <dbReference type="MEROPS" id="S08.069"/>
    <dbReference type="EnsemblBacteria" id="ADD43165">
        <property type="protein sequence ID" value="ADD43165"/>
        <property type="gene ID" value="Snas_3502"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3502"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007528_0_0_11"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049279" evidence="6">
        <location>
            <begin position="34"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="209"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1106" mass="116016" checksum="2C2B4663076C9DD2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVQ8</accession>
    <name>D3PVQ8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3509</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018743.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3509"/>
    <dbReference type="EnsemblBacteria" id="ADD43172">
        <property type="protein sequence ID" value="ADD43172"/>
        <property type="gene ID" value="Snas_3509"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3509"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_0_0_11"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="244"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="103"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="322" mass="34404" checksum="4DD5DB1A9F70AE5A" modified="2010-04-20" version="1">MIRTLVRNRVIQRIAQTLLTLFGVAIFIFVMLRAIPGDQITAGLGTEAAALTPAQRASLESYYGLDKPLVEQFFSWLGNVFTGNLGFSARAQESVLDLSLHALPVTAELAVLAIVLALLIGVPLGMLSASKPDSARDGFGQLVGLAGLSIPAFLLATLSLSILASTLGFNPNGEVFVTFVEDPLLNLQQMLLPSLVLGFGIAAPIMRTTRTAVLEVRSLDFVRTARAKGVPARRLQVKHVLGNALIPIVTMTGLQLGYLLGGAVVVEQIFSIPGIGRQVLLGIQQKEYALVQSTVLIIALAFVLVNLATDLLYRAIDPRVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVS5</accession>
    <name>D3PVS5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5414</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5414"/>
    <dbReference type="EnsemblBacteria" id="ADD45046">
        <property type="protein sequence ID" value="ADD45046"/>
        <property type="gene ID" value="Snas_5414"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5414"/>
    <dbReference type="HOGENOM" id="CLU_1947515_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="129" mass="14956" checksum="906AA1F0DD69220B" modified="2010-04-20" version="1">MEAKVLGRIVWRGYRWCGHTDMLRRSRDFPPLHPRHWTRFSATCIGQWADERRALDWLWNQMAEAHDHIVAEFPQRAVAIRSEYDDAAQRLCDSDDCACSWSIALPASIRLYVGIVAVYEHPSTIQGDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVW4</accession>
    <name>D3PVW4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020656.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5453"/>
    <dbReference type="EnsemblBacteria" id="ADD45085">
        <property type="protein sequence ID" value="ADD45085"/>
        <property type="gene ID" value="Snas_5453"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5453"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_3_0_11"/>
    <dbReference type="OMA" id="MSLVRVH"/>
    <dbReference type="OrthoDB" id="1920912at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="8"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="210" mass="22588" checksum="A172300B585383DB" modified="2010-04-20" version="1">MSEVRVHNFSISLDGFGTGDVQSADAPFGHAGERLHEWMFATRFWDKTGGSLGADNAFADRNSVGIGAEIMGAGKFGPPGWQDDADWKGWWGPNPPFHSPVIVLTHRPRPAIEMEGGTTFHFLDATPAEAIEQAKTAADGKDVRIGGGATVIRDCVAAGLVDHMHLVQVPIVLGRGVRVWDGLEALEDSFDIEATSTPSGVTHLTFTKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW02</accession>
    <name>D3PW02_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020694.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5492"/>
    <dbReference type="EnsemblBacteria" id="ADD45123">
        <property type="protein sequence ID" value="ADD45123"/>
        <property type="gene ID" value="Snas_5492"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5492"/>
    <dbReference type="eggNOG" id="ENOG5034AYS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_518657_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="561" mass="59578" checksum="985FCF72A2C9EE25" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW13</accession>
    <name>D3PW13_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_5503</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="7">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020705.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5503"/>
    <dbReference type="EnsemblBacteria" id="ADD45134">
        <property type="protein sequence ID" value="ADD45134"/>
        <property type="gene ID" value="Snas_5503"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5503"/>
    <dbReference type="eggNOG" id="COG1146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_0_3_11"/>
    <dbReference type="OMA" id="DRMLYIH"/>
    <dbReference type="OrthoDB" id="1873445at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000813">
        <property type="entry name" value="7Fe_ferredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00354">
        <property type="entry name" value="7FE8SFRDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="106" mass="11743" checksum="23BB998CEA75661F" modified="2010-04-20" version="1">MTYIIAEPCVDLLDKACIEECPVDCIYEGNRMLYIHPDECVDCGACEPVCPVEAIFYEDDVPEEWSDYTGANYEFFEELGSPGGASKVGKIEKDATFVASRPAKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW24</accession>
    <name>D3PW24_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5514</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020716.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5514"/>
    <dbReference type="EnsemblBacteria" id="ADD45145">
        <property type="protein sequence ID" value="ADD45145"/>
        <property type="gene ID" value="Snas_5514"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5514"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_4_11"/>
    <dbReference type="OMA" id="PSPPTWM"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="101"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="309" mass="33189" checksum="51B939C3B2EBA4B2" modified="2010-04-20" version="1">MSDVSAIEEAVTETPKVAKPASLFGDAVRDLRKRPTVILSVVIIVPILLIAFFPWLFTSVDPEVCRIAKVKAPPEPGHPFGFSPDGCDYYAQTIYGAGPSIKLSLMVVIGTLIIGGLVGILAGYYGGWLDAVFSRAVDTFNSIPFLLGALLMLSMFRNVEIPFVSANLAAILPAVITLIFFGWTSTMRLIRASVIESRGLDYVQAAKSLGASNRRIMFRHILPNAVAPVMSLIPLSIAGMISAEATLSFLGIGVRPPAISWGIMISKASDIFVTNPMLLIIPSIFLVATVLSFVLLGDAIRDALDPKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW71</accession>
    <name>D3PW71_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1524</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1524"/>
    <dbReference type="EnsemblBacteria" id="ADD41228">
        <property type="protein sequence ID" value="ADD41228"/>
        <property type="gene ID" value="Snas_1524"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1524"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="267"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="12"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="546" mass="56103" checksum="88DEBC8F076B7323" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWE7</accession>
    <name>D3PWE7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1601"/>
    <dbReference type="EnsemblBacteria" id="ADD41304">
        <property type="protein sequence ID" value="ADD41304"/>
        <property type="gene ID" value="Snas_1601"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1601"/>
    <dbReference type="HOGENOM" id="CLU_976296_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="285" mass="30023" checksum="6DF4497E27313FA8" modified="2010-04-20" version="1">MSALDRRTRILLGVGIGVVVLMVAAFGGVRLLTGATVDNAVAKFQPRYDSLRDKLTEVPGLLAKSELDKNSCSESRPKFHYVAADAGSDTKPDGNAEILMEPQTEHPDALIDYREHFGFGGSTLLEGLRLTGPKGYGGTGQFTLPSNAHPNGLAARLKNGADTRYLVVLRETGYTPPETGIDGDGGVSISAGFSGSVELDGYVVDLKAMTVDCRVTVDTPTPGGSLKYAKGQNPDEVLFERIQEDTGDTLARELERVTDGAAATPPTRGSTCGDADGDVVTAMCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWH6</accession>
    <name>D3PWH6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YCII-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3536</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018769.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3536"/>
    <dbReference type="EnsemblBacteria" id="ADD43198">
        <property type="protein sequence ID" value="ADD43198"/>
        <property type="gene ID" value="Snas_3536"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3536"/>
    <dbReference type="eggNOG" id="COG3795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130902_2_1_11"/>
    <dbReference type="OMA" id="YTRVEVR"/>
    <dbReference type="OrthoDB" id="2051456at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="112" mass="12540" checksum="D5B7600A4630C0D1" modified="2010-04-20" version="1">MEYLLLIYKDESRDGEFDWAQISQDYATFSKELVEAGAMRDGRRLQPSDTCTTVAVRDGEHLVTDGPFGEAREQLGGYYLLDCGDLDEALRWARRCPGASHGTVEIRPVAPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX50</accession>
    <name>D3PX50_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5644</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020845.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5644"/>
    <dbReference type="EnsemblBacteria" id="ADD45274">
        <property type="protein sequence ID" value="ADD45274"/>
        <property type="gene ID" value="Snas_5644"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5644"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="YDLDHYV"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="149"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="225" mass="24367" checksum="C89A7ED9987F3F46" modified="2010-04-20" version="1">MTEPLRVVVADDQALVRTGFRMILTADGMDVVAEAANGTEAIAAVRRTRPDVVLMDIRMPELDGLEAARRILAGGGDTRVVILTTFDLDHYVYAALSAGASGFLLKDVSPEHLVAAVRMVRDGDALLAPSITRRLVERFVGRDGDTTAIHRDLAALTPRELEVLRLLAQGLSNAELAARLHLSEATVKTHVARILAKLQLRDRVQAVIVAYETGLVSPSDRSTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXX8</accession>
    <name>D3PXX8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5677</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5677"/>
    <dbReference type="EnsemblBacteria" id="ADD45307">
        <property type="protein sequence ID" value="ADD45307"/>
        <property type="gene ID" value="Snas_5677"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5677"/>
    <dbReference type="eggNOG" id="COG3021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_896904_0_0_11"/>
    <dbReference type="OMA" id="CTTHILP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049343" evidence="2">
        <location>
            <begin position="27"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="3">
        <location>
            <begin position="35"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="33263" checksum="1920D9FE293F42E8" modified="2010-04-20" version="1">MRRSIRFAVAAVVAAAGLAVAPLAVADEATELNVLSWNTCGEAGGKRGDAGFCPYRDDPQAKVDVIADLVAERDLDVILLQEVCAETADSHLGRLKTALGDDWQIGNARGARPDGRTDCRGDLNGELGVAIAIKASNAEFTSKQTLPPDPTGQSKQTLPTLCATTTDWPTTVCTTHILADPEDPRRPQQVKNVRDYVWPSRANLVLGGDFNLFPGSSTLKPISDNFHECDGRSYGSGDKVDETTHHAWTGDDTHVYRKRDHIFASKPDSGTNFGSCDSRTDLMDTTENEPDSGPPSGYSDHAPLLGTVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYF9</accession>
    <name>D3PYF9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">sn-glycerol-3-phosphate transport system permease protein UgpE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1830</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017097.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1830"/>
    <dbReference type="EnsemblBacteria" id="ADD41526">
        <property type="protein sequence ID" value="ADD41526"/>
        <property type="gene ID" value="Snas_1830"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1830"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_1_11"/>
    <dbReference type="OMA" id="WVMIIPN"/>
    <dbReference type="OrthoDB" id="1074175at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055052">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015794">
        <property type="term" value="P:glycerol-3-phosphate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001407">
        <property type="term" value="P:glycerophosphodiester transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030165">
        <property type="entry name" value="UgpE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43744:SF8">
        <property type="entry name" value="PTHR43744:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="84"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="288" mass="31469" checksum="CF511636147C9A51" modified="2010-04-20" version="1">MALTPTIADSPETEPRPVRRRRGTVRLHVALIVICFVLCAPVVYALLIATQNNSEMANVQLWPGSSLADNFDVVWNKRNLGTFMLNSVLMAVIISGGKAVTGLLAGLAFVYFRFPGRWLVFFGVLVTLMMPTEISILALFGIVDDLGMSGNLSGLTIPFLASATAAFLFRQHFANLPANLSEAAQLDGANPMQFLFKVLIPVSWNVIGALTVIEFLYGWNMYLWPLLTVNDESDWVVQQGLASLQQAGEGLAYGPLMMGALIASIPPILVFLALQRPFMKGFAMSRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYL5</accession>
    <name>D3PYL5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3792</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">To bacterial alkanal monooxygenase alpha and beta chains.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019019.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3792"/>
    <dbReference type="EnsemblBacteria" id="ADD43448">
        <property type="protein sequence ID" value="ADD43448"/>
        <property type="gene ID" value="Snas_3792"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3792"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_9_0_11"/>
    <dbReference type="OMA" id="HHNMPSV"/>
    <dbReference type="OrthoDB" id="1003376at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019949">
        <property type="entry name" value="Luciferase_OxRdatse_group-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03558">
        <property type="entry name" value="oxido_grp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="2">
        <location>
            <begin position="26"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="361" mass="38650" checksum="C3A6073D47690A76" modified="2010-04-20" version="1">MNDTPQTPDPIRGSARGDAAVPLSVLDLATVSSGSDVATALRTTTDNARQAEALGYHRLWVAEHHSMPGIASSSPAVLLAHLAAATDTIRLGSGGVMLPNHAPLVVAEQFGTLEALHPGRIDLGLGRAPGTDQATMRALRRHNDPDPDDFDGQLDELVGFLDDAFGPRHPYAHIHAVPGPVQAKLSGTTASRPPIWLLGSSGYGARLAGQLGLPFAFAHHFAARNTLPALELYRENFMPSTVLDRPYAMVAASAVAADTEYEAARLARTMGLAMLRVRGGRPGLMPSPEEAEAYRYSDAEAEFVHSWLANVAFGEPHAVRQELDELIKATQADELMIVSNVHGHETRLRSFRLIAEAYGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ94</accession>
    <name>D3PZ94_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017139.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1872"/>
    <dbReference type="EnsemblBacteria" id="ADD41568">
        <property type="protein sequence ID" value="ADD41568"/>
        <property type="gene ID" value="Snas_1872"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1872"/>
    <dbReference type="HOGENOM" id="CLU_1569736_0_0_11"/>
    <dbReference type="OrthoDB" id="2080678at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="170" mass="18302" checksum="A94EDEA4FBBC9558" modified="2010-04-20" version="1">MTDETINTEQPELRKSRFGYRARFVAIVVLLSITLLGGVALALVLAEDKPKPRSVEDQAIDMCQDAVLQSLKAPSTADFVGEPIAFSDGGEVAPVYTVTGEVDAENSFGAMLRNLYTCDIQTSNDRDSWTVEAVDIVLCAAETGRGQSWVTGRGRGGTGVDWMIEVVVCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZP1</accession>
    <name>D3PZP1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019149.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3923"/>
    <dbReference type="EnsemblBacteria" id="ADD43578">
        <property type="protein sequence ID" value="ADD43578"/>
        <property type="gene ID" value="Snas_3923"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3923"/>
    <dbReference type="HOGENOM" id="CLU_1561933_0_0_11"/>
    <dbReference type="OrthoDB" id="2011443at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="171" mass="19163" checksum="D542DD2D826F8D1F" modified="2010-04-20" version="1">MTDKGVLGLRRPRLAAAQLVWLPLLVAGAAWLTLRSVDWEAPLWQLWLLALVIVAAATLSAPLGSPYLEQDDLLPVHAEPGAARSFGSVSRWESRLSGQRDVEDFQRVVQQNLILVIAERLRLRHGVELAHDGPRARQLLGDELYRFCVRPVAVAPSRAELERLITRIERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZQ4</accession>
    <name>D3PZQ4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3938</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019162.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3938"/>
    <dbReference type="EnsemblBacteria" id="ADD43591">
        <property type="protein sequence ID" value="ADD43591"/>
        <property type="gene ID" value="Snas_3938"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3938"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_4_2_11"/>
    <dbReference type="OMA" id="VINIRTY"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="133" mass="14491" checksum="9A420BEC84A1F7C8" modified="2010-04-20" version="1">MRKTYDNPEAAPKPGGHYTNVIKVESGDSVTLHLSGQIALDHDGEVVAPGDMTKQSHVVMEIIGKLLAAHGAGFDDIVNIRTFLTDMDRLREYGDVRRTYFDGEPPTSTTVEVTRLFRPGALLEVEVVAVIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZT1</accession>
    <name>D3PZT1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amidohydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3966</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3966"/>
    <dbReference type="EnsemblBacteria" id="ADD43618">
        <property type="protein sequence ID" value="ADD43618"/>
        <property type="gene ID" value="Snas_3966"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3966"/>
    <dbReference type="eggNOG" id="COG2159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_325938_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018891">
        <property type="entry name" value="Abortive_phage_infection"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10592">
        <property type="entry name" value="AIPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="3">
        <location>
            <begin position="614"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="563"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="884" mass="98759" checksum="F2D805206AD4F80F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZW9</accession>
    <name>D3PZW9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell wall synthesis protein Wag31</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Antigen 84</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_4004</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DivIVA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019227.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4004"/>
    <dbReference type="EnsemblBacteria" id="ADD43656">
        <property type="protein sequence ID" value="ADD43656"/>
        <property type="gene ID" value="Snas_4004"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4004"/>
    <dbReference type="eggNOG" id="COG3599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062236_0_0_11"/>
    <dbReference type="OMA" id="VNKRFQP"/>
    <dbReference type="OrthoDB" id="875822at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019933">
        <property type="entry name" value="DivIVA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007793">
        <property type="entry name" value="DivIVA_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35794">
        <property type="entry name" value="PTHR35794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05103">
        <property type="entry name" value="DivIVA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03544">
        <property type="entry name" value="DivI1A_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="218"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="25"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="150"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD43656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="254" mass="27962" checksum="AFFF86841EE66C42" modified="2010-04-20" version="1">MPLTPADVHSISFKKAPIGNRGYDEDEVDNFLDEVERELERLIEANNQLRKQNEQLAAGAPAGSVDNAELLAEFERLQHEKVQAEKAAAALESELDELRRSGALSNGPGAQGPEGGEQQALRLLMVAQRTADDHLESARSEADTVLTEARTEADSVLTKARSQAESLEEEAQRRHKEIMNNLESKRAALHKHIEELKTFERQYRTRLKAYLESQLRDLTGRGEGVIEGDSSDQGELRSSGPSPALTAAGNDAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZY0</accession>
    <name>D3PZY0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
            <ecNumber evidence="6 7">6.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">D-alanyl-D-alanine-adding enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">murF</name>
        <name evidence="11" type="ordered locus">Snas_4015</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="6 7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019238.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4015"/>
    <dbReference type="EnsemblBacteria" id="ADD43667">
        <property type="protein sequence ID" value="ADD43667"/>
        <property type="gene ID" value="Snas_4015"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4015"/>
    <dbReference type="eggNOG" id="COG0770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031507_0_0_11"/>
    <dbReference type="OMA" id="VEMGANH"/>
    <dbReference type="OrthoDB" id="1861122at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="8">
        <location>
            <begin position="31"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="10">
        <location>
            <begin position="108"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="9">
        <location>
            <begin position="316"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="110"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD43667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="463" mass="47969" checksum="93BF686C5194A3CF" modified="2010-04-20" version="1">MIAMSLAEIAEAVGGRLSDTANPETRVTGPVEHDSRKIEPGSLFVAFTGEHADGHDFAAAAVADGAVAALVSREVDAPSILVDDVQLAFGKLARAVVDRLPELKIIGVTGSAGKTSTKDVMAELCRALGPTVAPEGTLNNEIGLPYTVLKVDETTRYLVLEYSARGIGHIDYLCGIAPPGIAVVINVGTAHMGEFGTVDGIARAKGELAEAVAPGGVVILNADDARVAAMRDRARARVVTFGEAESADIRATDVVSEAGQPRFTLHTPNGSAPVALKLYGAHHVSNTLAAAAVAVELGMAAEAIASVVSGPLSLSPRRMDVFTRADGTTVIDDSYNANPSSMAAAINALADLGKESRKIAVLGYMAELGDETEAAHLQVGELAARNDIDIVISVEEVAAAIAEGAGLAGSIAYGVDDQAEAIAKLDELLDVGDVVLVKGSRYRTWKVADYLRETRNSTKEAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZZ1</accession>
    <name>D3PZZ1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hydrolase_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019249.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4026"/>
    <dbReference type="EnsemblBacteria" id="ADD43678">
        <property type="protein sequence ID" value="ADD43678"/>
        <property type="gene ID" value="Snas_4026"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4026"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029375_2_1_11"/>
    <dbReference type="OMA" id="PNGGHND"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="71"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="278" mass="29551" checksum="BE356A9EBCF582C3" modified="2010-04-20" version="1">MVKRRFLRTVLVAVAVIVLLLTMAWWFQRQLIYFPDTSAPPVPDSATEVELRTSDDLKLAAWQFAPTGADRKTAVLVANGNGGNRLNRIGLAEALTAKGFTVLVFDYRGYGGNPGSPDEDGLYADAKAALDHLTGPAGFDTDRIVYFGESLGCGVVSKLALDHPPAAMVLRSPFTSLPDVGQRHYPYLPVRLLLTETYPVESNVTKTGVPLLVAYGTGDSIVPPDLSKRVAESAENSGAEVTKLAIDGADHNELELVGGAEVIDGVATLADSAGLTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZZ5</accession>
    <name>D3PZZ5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5896"/>
    <dbReference type="EnsemblBacteria" id="ADD45524">
        <property type="protein sequence ID" value="ADD45524"/>
        <property type="gene ID" value="Snas_5896"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5896"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049031_0_0_11"/>
    <dbReference type="OMA" id="TWALMRE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="325" mass="34558" checksum="42BB6479E2053FE6" modified="2010-04-20" version="1">MSSMVRHVRPVAPRWARGVVADVYRHVGSEFADIGPTVRMASPTPEILAPGWALLWESRLAGELPLPHKLLAGLGVAQANRCGHDEDDWLAALRRAGAGELAEQVAAGGPPDEARLTRLFDWARATAFDPSARMPVRLRPKPAPELIGTVLFAHFRDRMSLAMLAPGLSPGIEAAASAPLWRNSRPVLRPGDTLTLLKRTGKTPDWGADSPVGIAYGALAANAARGAGMMSAEAAHTVTEVIAAYRGRIQPDPSLICLGELNRLSEADRFAARAAILAGLAPAELTDADVLAWRATDRHLSDHCTVLLLAYGAMTAVAHIEADIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q058</accession>
    <name>D3Q058_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L7/L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplL</name>
        <name evidence="7" type="ordered locus">Snas_5960</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021158.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5960"/>
    <dbReference type="EnsemblBacteria" id="ADD45587">
        <property type="protein sequence ID" value="ADD45587"/>
        <property type="gene ID" value="Snas_5960"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5960"/>
    <dbReference type="eggNOG" id="COG0222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086499_3_0_11"/>
    <dbReference type="OMA" id="LEDKWGV"/>
    <dbReference type="OrthoDB" id="1822695at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L12_N" evidence="6">
        <location>
            <begin position="7"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="5">
        <location>
            <begin position="62"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="128" mass="13346" checksum="8594519F48BEB85A" modified="2010-04-20" version="1">MAKLSNAELLDVFKEMTLLELSEFVKEFEETFDVTAAAPVAVAAAGGAGGGGEAAAEEKDEFDVVLEAAGDKKIQVIKEVRGLTSLGLKEAKELVEGAPKPVLEKAKKEDAEKAKEALEAAGATVSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0L3</accession>
    <name>D3Q0L3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017320.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2055"/>
    <dbReference type="EnsemblBacteria" id="ADD41749">
        <property type="protein sequence ID" value="ADD41749"/>
        <property type="gene ID" value="Snas_2055"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2055"/>
    <dbReference type="HOGENOM" id="CLU_168932_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="96" mass="10141" checksum="8016919D5A93D183" modified="2010-04-20" version="1">MATDDSIGADNAPPPRLLRWLERLPKVAIFIGVLVITVGFLWTPGLTGAILTTALAAGAAFLLYATWPAHTATSTRLVRVLVVAVLAVLGIAKFFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0V8</accession>
    <name>D3Q0V8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MbtH domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019279.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4056"/>
    <dbReference type="EnsemblBacteria" id="ADD43708">
        <property type="protein sequence ID" value="ADD43708"/>
        <property type="gene ID" value="Snas_4056"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4056"/>
    <dbReference type="eggNOG" id="COG3251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_181321_0_1_11"/>
    <dbReference type="OMA" id="REDCLAH"/>
    <dbReference type="OrthoDB" id="2067093at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005153">
        <property type="entry name" value="MbtH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038020">
        <property type="entry name" value="MbtH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037407">
        <property type="entry name" value="MLP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38444">
        <property type="entry name" value="PTHR38444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03621">
        <property type="entry name" value="MbtH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00923">
        <property type="entry name" value="MbtH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160582">
        <property type="entry name" value="SSF160582"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MbtH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="68" mass="7605" checksum="EC2F713320EE41C0" modified="2010-04-20" version="1">MFEDNDGREYVVVRNDVNQYSIWPSDRQPPTGWAPAGRTGSKADCLAEIAEVWTDMRPAPRTGTDAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q105</accession>
    <name>D3Q105_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4104</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4104"/>
    <dbReference type="EnsemblBacteria" id="ADD43755">
        <property type="protein sequence ID" value="ADD43755"/>
        <property type="gene ID" value="Snas_4104"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4104"/>
    <dbReference type="HOGENOM" id="CLU_3405625_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="30" mass="3128" checksum="DA9542624B0729DE" modified="2010-04-20" version="1">MVIGIIAAAAAVLVCACTVTILRRRSKNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q126</accession>
    <name>D3Q126_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4125"/>
    <dbReference type="EnsemblBacteria" id="ADD43776">
        <property type="protein sequence ID" value="ADD43776"/>
        <property type="gene ID" value="Snas_4125"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4125"/>
    <dbReference type="eggNOG" id="COG0476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_938870_0_0_11"/>
    <dbReference type="OMA" id="SGTPHLY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="290" mass="31287" checksum="78DB01BB3A7C3497" modified="2010-04-20" version="1">MDGMNHFRFLPGLRRVPLRPDFVQLGSDPDRSYLLQLPDSRLSQLLERLDGWIDETTYQLAAHALGVAGSEASGLLNLLRGKGLVVDSGAVTAEGSPEAHALALRRDRTPATVLAARRRQRVFVNGTGALARRTAVTLRAAGLGRVWCADEGRRGKATLTVLVNCAYPPTLAARGHARRRLPYLTVAILDGAVHIGPMVSPGTTPCLRCVDLHYRDCLPAWHTGGEPEILEASVATLAAGCVASAALQRLDGERCAVEASTIEIRPSLVIRRREWNVHPDCGCASTDTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1C6</accession>
    <name>D3Q1C6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021277.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6082"/>
    <dbReference type="EnsemblBacteria" id="ADD45706">
        <property type="protein sequence ID" value="ADD45706"/>
        <property type="gene ID" value="Snas_6082"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6082"/>
    <dbReference type="HOGENOM" id="CLU_2791968_0_0_11"/>
    <dbReference type="OMA" id="IHTIPPH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="68" mass="7512" checksum="FDCC607AD704D88E" modified="2010-04-20" version="1">MKRHSPDTLSLIAGLFFATLAVVWLIDDIHTIPPHAIGWIFASVFTLAGLVGLVRAIRRPRSEETDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1G9</accession>
    <name>D3Q1G9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021320.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45749">
        <property type="protein sequence ID" value="ADD45749"/>
        <property type="gene ID" value="Snas_6125"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6125"/>
    <dbReference type="HOGENOM" id="CLU_2556655_0_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="82" mass="9130" checksum="5DC412DF9BB04466" modified="2010-04-20" version="1">MWTKQGKYDEIDVVDGEMITTAFSKANGHVEPIQVFDWRTGKGKWQLAGGELVAHDDDHFVFVDPDAADGPTLSVVSRENPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1H9</accession>
    <name>D3Q1H9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015398.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0106"/>
    <dbReference type="EnsemblBacteria" id="ADD39827">
        <property type="protein sequence ID" value="ADD39827"/>
        <property type="gene ID" value="Snas_0106"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0106"/>
    <dbReference type="HOGENOM" id="CLU_799036_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="252"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="339" mass="36000" checksum="804716C9EAB8B62D" modified="2010-04-20" version="1">MGRNDSEFPSDEELKKLAGKIKGAAIRANTKILKSYDPDTYGNYLDQLDGIRSQAEWLGTAFDDFLKPSPWDFDDMLKALDEIASDLGQAVGETEIKNGIVQGRIDTTKQFLGEGGWKGALADSFKMDYLEPIGSHIAANQGAVTLVTHDGLQAMRDIYGKARENLKDLGEKAVTAFEQADGISASDLKTLLTVLSAAFGLGTAVLSAFAPAAAAGAGIASALVSGGIAVGSDKVGEDEESELAADYPDKVEENFKNALEKLKEQITTMEDELIKVLQKGTSDIASIVWGEKLDRLNGFSALFGMGNQSLLAPKVPDLSMVAFGDDPGKLKDGLVQVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1J3</accession>
    <name>D3Q1J3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015412.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0120"/>
    <dbReference type="EnsemblBacteria" id="ADD39841">
        <property type="protein sequence ID" value="ADD39841"/>
        <property type="gene ID" value="Snas_0120"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0120"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_40_3_11"/>
    <dbReference type="OMA" id="ELTREWG"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="4"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="193" mass="21279" checksum="85BFAFB25EDB7A7A" modified="2010-04-20" version="1">MPKPDTAQRIAEAALAILIAEGPKAVTMRRVAADAGVTTMASYRHFPNRETLLRTVADNAFAELGKTWGERDQLGDFDTRLRANLDDFLDFALTKPNLYTFLLTDRRDGNRQFPQDFGGDRSPAFAPLLATVEQGMRDGLLRSDDPLEVTLAIATTGMGLVDLYLGGRIGMPETEFRALCLRTAERVLNGCRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1S9</accession>
    <name>D3Q1S9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0208</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015498.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0208"/>
    <dbReference type="EnsemblBacteria" id="ADD39927">
        <property type="protein sequence ID" value="ADD39927"/>
        <property type="gene ID" value="Snas_0208"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0208"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="NTFHEVG"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="22"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD39927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="474" mass="47904" checksum="2309EF95DEBC6FC7" modified="2010-04-20" version="1">MTTETPSTESPRVAPHPWRWRILGFLGIAQLMLILDVTVVAIALPHIETDLDLSREALTWTVSAYPLAFGGLMLLGGRLADLWGAKRIVLAGLLTFTAASLVTGLATDGAVLLGGRVAQGVGAAMLSPAALSLVVTLFDGRERDKALGVWSALGGGGAALGVLVGGLLTTGPGWSWVFYVNVPVGAVIIVVLAKLLPRTGSAAVRGRLDILGALLVTASSGAVIYALISAGEAGWLTVANGVLALLAIAGYTAFVWWQKRSHSPLMDVRLLARRPVATGTFLILVATALMIAVFFLGTFYFQRARDYSALHTGLLFLPIAVATMLGANLTGRALGRFGARTLAIAGLLLAALGLAAPVVVMSPVVVVVGVAIAAAGTGALFVVASATALGQVSPQEAGVASGIVSTFHEFGASVGAAVVSSVAAASLIGDTLSGFTDGFVVIASAAAVAAVIAGFLTPGKQPTGSGAGAHLPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2G8</accession>
    <name>D3Q2G8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019472.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4252"/>
    <dbReference type="EnsemblBacteria" id="ADD43901">
        <property type="protein sequence ID" value="ADD43901"/>
        <property type="gene ID" value="Snas_4252"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4252"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108054_0_1_11"/>
    <dbReference type="OMA" id="RHVTIDC"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="129" mass="14312" checksum="A1E2B92CC338A7BF" modified="2010-04-20" version="1">MVATVRHITVDCANAYELARFWSEVTGWPISDQDEPGDAEVLLEAPAPMPGMLFIQVPEGKHSEPRTGRRIHLDVIPTDRTRDEEVERLKGIGAAGYEDHRKPDGTGWVTMADPEGNLFCVERSAAERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2M5</accession>
    <name>D3Q2M5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_6153</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021347.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6153"/>
    <dbReference type="EnsemblBacteria" id="ADD45776">
        <property type="protein sequence ID" value="ADD45776"/>
        <property type="gene ID" value="Snas_6153"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6153"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="VACHWAE"/>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="342" mass="37520" checksum="4B59AECA59AF935A" modified="2010-04-20" version="1">MSLLELEDLKVHFPIKRGVIFDRTVGHVYAVDGVSLSVESGQTYGLVGESGCGKTTLGRAVLRLNEITSGAVKFDGTDLAQLPREQMRQARRRLQMVFQDPMGSLDPRQNVESILVEGLHAHGIGSNRTERRQRIQRTLDAVGLPSAALARYPHEFSGGQRQRIGIARALVLEPDLIICDEPVSALDVSIQAQVLNLLEEIQDELGLTYLVIAHDLAVVRHISDVIGVMYLGSLVEEAGSDMLYAEPKHPYTKALMSAVPVPDPQVEDARERILLSGDLPSPAAPPPGCRFHTRCPWKQDTLCATERPQLRVLSEGHKVACHWAEKIEAGEITPRSEAVISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2R3</accession>
    <name>D3Q2R3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4037 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021385.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6191"/>
    <dbReference type="EnsemblBacteria" id="ADD45814">
        <property type="protein sequence ID" value="ADD45814"/>
        <property type="gene ID" value="Snas_6191"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6191"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056336_0_0_11"/>
    <dbReference type="OMA" id="DHDWGPR"/>
    <dbReference type="OrthoDB" id="681174at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025117">
        <property type="entry name" value="DUF4037"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13228">
        <property type="entry name" value="DUF4037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4037" evidence="1">
        <location>
            <begin position="148"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="367" mass="40653" checksum="407DB79706B44984" modified="2010-04-20" version="1">MAGEGEFLPGLELCRALYVDGVKPILESRYPDLRHSAARIGAGSEVQGFDTPVSPDHGWGPRLQLFLAPSDAAAVGAELTETLSRLLPRRIRGWSTHFAPSGDEPGASDVLADTDGPVAHGVEIADCATWFTRKLGVDATRRLDALEWLCVPQQYLAEATAGAVFHDGLGQLEPIRRRLTWYPEQVWRYLLASQWMKLSQEEAFVGRTAQVGDELGSMVVAARQVRELMRLALLQTRVYAPYSKWLGSAFARSVPEAAKLDASLRSALSAATYPERERHLCDAYEELARRHNALDLTPALDPSRRQFFDRPFQILGADRFANALRDSISHPELKRLPLTGAVDQWADNTDYIAQDDAIAASIRALRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2U3</accession>
    <name>D3Q2U3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021415.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6223"/>
    <dbReference type="EnsemblBacteria" id="ADD45844">
        <property type="protein sequence ID" value="ADD45844"/>
        <property type="gene ID" value="Snas_6223"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6223"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043786_1_0_11"/>
    <dbReference type="OMA" id="YRPDREW"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="332" mass="36886" checksum="A67EAD80E27290D8" modified="2010-04-20" version="1">MQVTPFDPATASEHELAGWRDVLNAVVASDMPGEPEWHSDRLRDYLAVTMPQEQRVAFVARDGGGDMAGHANLLLFSGDFSGTGIFEIFVHPTQRGSGVGRDLLKQVAQRAAAEGRETIGVEVIATTPAVGFYEHYGFVPSVIENRHLLNMRDMDWERVRDGSRRIAAGYRLEYYSGGLPESMLERYASTKVHLRVNGETSWRGSADARRLRDSLDTLANRGLRTHLVVAIAEPAESVVGLTELVVAAQRPTRGDQYDTVVAPEHRSYGLGLAMKARMLCELAENEPQLVDVQTWTASDGDPYAHVDAQLGFRNDVEWYEYEANVQQLLSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2U6</accession>
    <name>D3Q2U6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021418.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6226"/>
    <dbReference type="EnsemblBacteria" id="ADD45847">
        <property type="protein sequence ID" value="ADD45847"/>
        <property type="gene ID" value="Snas_6226"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6226"/>
    <dbReference type="HOGENOM" id="CLU_110577_0_0_11"/>
    <dbReference type="OrthoDB" id="1897239at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015068">
        <property type="entry name" value="DUF1877"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035944">
        <property type="entry name" value="YfbM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08974">
        <property type="entry name" value="DUF1877"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111069">
        <property type="entry name" value="SSF111069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="159" mass="17786" checksum="3BA084F043D67FC6" modified="2010-04-20" version="1">MGMYMTFVRLTPAELTKAVNDPEWAEEFVDEFYEDDDIDPLADLDLEKSWGGLIYLSDEAGLGLSLLDSGTRIISDDTCIDGWDADEVKATAKALSETPFSKLVAHYNPAAMMSQEVYPRVWDADPEGELESLEWNYRQMVEFFTAAAAANHAVLMSWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3B1</accession>
    <name>D3Q3B1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2263</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017523.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2263"/>
    <dbReference type="EnsemblBacteria" id="ADD41952">
        <property type="protein sequence ID" value="ADD41952"/>
        <property type="gene ID" value="Snas_2263"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2263"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_11"/>
    <dbReference type="OMA" id="TWRIFWR"/>
    <dbReference type="OrthoDB" id="1584669at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="65"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="270" mass="29333" checksum="EFE509B5184B6F8B" modified="2010-04-20" version="1">MSRVIRTTVLSVLGLFWLIPVYLLVVNASKSPEAFSSKDSWLPADFALFDNISEAMRLSGMAESAASTLLYSVVSPALAVLVGAAAGFAIVALRLRHGFAWFVVIFGGTVFPLQMILLPLMDSYTRIEVFDTQLGMIIVYTAISIPFSAFVMRNFFTGIANNVFEAAVLDGASTWRIFSRVYLPMAKSALVAVFILQATFIWNDFLLGLVLSQSDSVRPIMTSLSGMQSTYGGAQMSVVLAGGLLVSLPTVVLFLFTQKFFARGLALGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3C7</accession>
    <name>D3Q3C7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2279"/>
    <dbReference type="EnsemblBacteria" id="ADD41968">
        <property type="protein sequence ID" value="ADD41968"/>
        <property type="gene ID" value="Snas_2279"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2279"/>
    <dbReference type="HOGENOM" id="CLU_733438_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="377" mass="42275" checksum="51B441486F57D908" modified="2010-04-20" version="1">MAMRKRFGRYWFGNPGHLWMALRVGGGLLLAAVVLSVAGLHGLELEQPWRLVLAGAAVVSLAGTVACVAYIRRRTIVDERGVKVVRAWSSQRVGWTEIRGLAMGQDDGRWVLWADVAGGELVLFTYQLRGYGDDGPILGSSGSVDSAVLPDWAAPPFRSACAVIEHHWRGHVGPHARITARQPASPTVDAQAPLPVSASPPVERRLLRDRRFVSEVALWTTGMVLLFPVYMVIKWSRRDSPITWTWFLSLVAVFTAIMVAYFVARTREGTIVTSRGITLVRSLGFSRQRLPWSRIHGLELEHAWGQWLIQARTETGPTTVYHRRPGVEIPIGELILIQPRFRAHPNGSYPRPTDGTPMPVREAFALLHDYWHHHRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3E7</accession>
    <name>D3Q3E7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2299</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2299"/>
    <dbReference type="EnsemblBacteria" id="ADD41988">
        <property type="protein sequence ID" value="ADD41988"/>
        <property type="gene ID" value="Snas_2299"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2299"/>
    <dbReference type="eggNOG" id="ENOG5032DYH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_747846_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="386" mass="42144" checksum="465C0921E4A72A9C" modified="2010-04-20" version="1">MMRSVLDMASERASADAKAEPSKTPWWKKRRNLKILAVALVAVVAVSNLGYQLTRPGPEAVVSDYLSAIQDGDVDVALDYVDGIWEFDEVSDDLLVSGAMTTDWKVTNVARRPGVDPLVANIDFTITAADKTTRTGRFELLDNGSDWQILNPLAKIDVVAMPVGFAEFNRVVGYPSTTTKTDDSRTLVQKPARQLWMFPGAYDPYVDSDELVKPRMSSYIAIPSKYLRGEAVMLSSQTFAPELVPGKKFVKEVNRQFTDWLDKCAASSRIAPKNCPFAAGAGARRGAVSLEPDQEYLTEKADWKVTAHPEIELIQANGKFIVREVKPGTVAISGEGEPADQRDGFPVPFSGECTIDMASLSVTLAKPGDFAFKAQRPASNCAPTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3L8</accession>
    <name>D3Q3L8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FMN-dependent alpha-hydroxy acid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2374</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017630.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2374"/>
    <dbReference type="EnsemblBacteria" id="ADD42059">
        <property type="protein sequence ID" value="ADD42059"/>
        <property type="gene ID" value="Snas_2374"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2374"/>
    <dbReference type="eggNOG" id="COG1304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020639_0_0_11"/>
    <dbReference type="OMA" id="FQYEIYL"/>
    <dbReference type="OrthoDB" id="1186741at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="100"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="349"/>
            <end position="353"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="372"/>
            <end position="373"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="421" mass="45198" checksum="4EF9677012D9D72B" modified="2010-04-20" version="1">MRESVGRAVQSQIYRDGVYGRKPAVPVAAAALRDAAHRRLSKRALGYVAGSAGLETTATANRAAFDAWRVVPHILTDVSERDLGVDLFGRRRPTPYLLAPIGVLDLVHPEADLAVARAATDAGVPMIVSSQASTPMEDIAAAIGGGSWWFQLYWSREDALMESFVSRAEKAGAEAIVVTLDTHLLGWRPRDLDDAYLPFAFGRGIAQYTSDPVFTALVRERATRPRTTQRPTLAALSALASIARHHPGGFWTNLRSPLPRAAVETFLDVFSRPTLTWDDLEKLRQHTTLPILLKGVLHPDDAVRAVDSGVDGIVVSNHGGRQIDGAIASLEALPRVVTAVEDAIPVLFDSGIRGGADAYKALALGAHAVCLGRPYVYGLTLAGTIGVRQVLSHFIAELDLTLGLSGCTSIPDITRDTLRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3N4</accession>
    <name>D3Q3N4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4304"/>
    <dbReference type="EnsemblBacteria" id="ADD43951">
        <property type="protein sequence ID" value="ADD43951"/>
        <property type="gene ID" value="Snas_4304"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4304"/>
    <dbReference type="eggNOG" id="COG1476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_44_1_11"/>
    <dbReference type="OMA" id="VHNRISV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="80" mass="9169" checksum="AAC96E85C859BE1C" modified="2010-04-20" version="1">MATNNEVIYNRIAMLRAERGISRRQLAEALGVHYQTIGYLERGEYSPSLYLALRIAQYFEVEVEVVFSTAPFPRIGSERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3P5</accession>
    <name>D3Q3P5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019533.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4315"/>
    <dbReference type="EnsemblBacteria" id="ADD43962">
        <property type="protein sequence ID" value="ADD43962"/>
        <property type="gene ID" value="Snas_4315"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4315"/>
    <dbReference type="HOGENOM" id="CLU_184556_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="95" mass="11216" checksum="78B3AF1C36355890" modified="2010-04-20" version="1">MTIYGQFRDPLHTYVVTSSSMPDTIRVFAGDPHSAEMVCTISNLSARPYPSWNAKWYSNWPEWKRRFTDHAVSIWRTHNDHRPSPTRREFRTCDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3R1</accession>
    <name>D3Q3R1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">6-phosphogluconate dehydrogenase NAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4331</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019549.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4331"/>
    <dbReference type="EnsemblBacteria" id="ADD43978">
        <property type="protein sequence ID" value="ADD43978"/>
        <property type="gene ID" value="Snas_4331"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4331"/>
    <dbReference type="eggNOG" id="COG2084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035117_2_1_11"/>
    <dbReference type="OMA" id="MYGMFAG"/>
    <dbReference type="OrthoDB" id="1194694at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048846" evidence="1">
        <location>
            <begin position="23"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_binding_2" evidence="2">
        <location>
            <begin position="9"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="293" mass="30127" checksum="2CFB2818D4BE08DD" modified="2010-04-20" version="1">MAVDDAARVTVLGLGLMGKALAATLAKAGHATTVWNRTPGKAADLKSQGIAEAATLSEAVTASPLVVAVLLDHASVHDALDPVVGELSGRTLVNLTSTAPNQARELAQWAAANDIAYLDGGIMATPDMIGQAGSSILYSGTESVHAKYKPLLELWGEAAYFGDDAGLASLWDFALLSGMYTMFAGFYHGAAMVASAGVSADAFAARAVPWLTAIAPHIAAQAPAMDSGDYSTDVQHLNFTKAAADSIHQAGVDAGINPVVFAQFKALVDQQVADGHGAASFTRVFESLKNSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3S8</accession>
    <name>D3Q3S8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asp23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019566.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4348"/>
    <dbReference type="EnsemblBacteria" id="ADD43995">
        <property type="protein sequence ID" value="ADD43995"/>
        <property type="gene ID" value="Snas_4348"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4348"/>
    <dbReference type="eggNOG" id="COG1302">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113198_1_0_11"/>
    <dbReference type="OMA" id="DGVHAMG"/>
    <dbReference type="OrthoDB" id="2035639at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005531">
        <property type="entry name" value="Asp23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34297">
        <property type="entry name" value="PTHR34297"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03780">
        <property type="entry name" value="Asp23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="162" mass="16885" checksum="99C65D8C3B9632E3" modified="2010-04-20" version="1">MANTTTATKTTGGEAPAKAGTARPAARKTHSKLVTDTGSTTIAEGVVSKIAGLAAREIPGVHSMGTSMSRRIGQLKSLVPGASGTPSQGVAVEVGERETAIDLDVVTWYGQSIVDVTEAVRDNVVERVQDMTGLKVVEVNINVDDVFVEGQDSAEPKEPRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3X3</accession>
    <name>D3Q3X3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4393</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019611.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4393"/>
    <dbReference type="EnsemblBacteria" id="ADD44040">
        <property type="protein sequence ID" value="ADD44040"/>
        <property type="gene ID" value="Snas_4393"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4393"/>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_1_1_11"/>
    <dbReference type="OMA" id="QFLAAHT"/>
    <dbReference type="OrthoDB" id="1308229at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="2">
        <location>
            <begin position="8"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="379"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="683" mass="72635" checksum="FE29F260B2ED1CDF" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q494</accession>
    <name>D3Q494_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAD-superfamily subfamily IB hydrolase, TIGR01490</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily. SerB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021550.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6363"/>
    <dbReference type="EnsemblBacteria" id="ADD45979">
        <property type="protein sequence ID" value="ADD45979"/>
        <property type="gene ID" value="Snas_6363"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6363"/>
    <dbReference type="eggNOG" id="COG0560">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052657_1_0_11"/>
    <dbReference type="OMA" id="DHDQMER"/>
    <dbReference type="OrthoDB" id="1472357at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006385">
        <property type="entry name" value="HAD_hydro_SerB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01490">
        <property type="entry name" value="HAD-SF-IB-hyp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="272" mass="29732" checksum="C22BD66B603B6A8F" modified="2010-04-20" version="1">MSPSTASSAAFFDLDKTMIAKSSALAFGRPLYHGGLMARSDVLKAAYAQLAYLIAGADEDQMARTRDYLAQLCRGWETQQVSKIVAETLGELIDPYIYAEAVALVAEHRAAGRDIVLVSASGDELVRPIGRLLGIEDVIATRMVIEDGRYSGEIEFYAAGPAKAEAMAEFAEERGYDLKDCYAYSDSMTDMPMLEAVGHPTAVNPDRGLRKLALERGWPILSFKHPISLRRRVAALRHRPAVPATAVGVGVGLALTVALVWYSRKRKRRNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4K3</accession>
    <name>D3Q4K3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0448</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015734.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0448"/>
    <dbReference type="EnsemblBacteria" id="ADD40163">
        <property type="protein sequence ID" value="ADD40163"/>
        <property type="gene ID" value="Snas_0448"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0448"/>
    <dbReference type="HOGENOM" id="CLU_2720404_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="72" mass="7590" checksum="86ECC1001378A125" modified="2010-04-20" version="1">MERDDARAVATRAADYTKLRRGAAAERMLRAALTSEPGNGVLLIELARALHAQKRHDEALSAAESGTTSGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Z0</accession>
    <name>D3Q4Z0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017741.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2487"/>
    <dbReference type="EnsemblBacteria" id="ADD42170">
        <property type="protein sequence ID" value="ADD42170"/>
        <property type="gene ID" value="Snas_2487"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2487"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_6_11"/>
    <dbReference type="OMA" id="VYLEDHW"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="174" mass="19677" checksum="D2E5A6B8AE632048" modified="2010-04-20" version="1">MPPSLKLRPIVMDDWTAVHDWARLDESCRYQGWGPNTEHETRAFVERAVAGWNVEPVRHRVYVAEVDGEIVGSGVLHFRDRRHRQGEISYGVHPKLWGRGLGTAVGAELLRVGFDGLGLHRIAATCDPRNRASAAVLGKLGMSFEGRMRHTRRIGDGWRDSDLYSILDGEWRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q522</accession>
    <name>D3Q522_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chromosome segregation and condensation protein, ScpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4426</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019642.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4426"/>
    <dbReference type="EnsemblBacteria" id="ADD44071">
        <property type="protein sequence ID" value="ADD44071"/>
        <property type="gene ID" value="Snas_4426"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4426"/>
    <dbReference type="eggNOG" id="COG1386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045647_5_1_11"/>
    <dbReference type="OMA" id="DGWRFYT"/>
    <dbReference type="OrthoDB" id="1771906at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051304">
        <property type="term" value="P:chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005234">
        <property type="entry name" value="ScpB_csome_segregation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34298">
        <property type="entry name" value="PTHR34298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04079">
        <property type="entry name" value="SMC_ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00281">
        <property type="entry name" value="TIGR00281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="261" mass="28452" checksum="34E73B125594DE8E" modified="2010-04-20" version="1">MNNAEPAEEQGTSGSLAADIAEWSPPWQREEPRDTPADEPVEFAEPVSDGVAETPADTDAPRPEPEPVKAPEPEPEPLPLSQDLAGTLEAILMVSDEPVSETILAQTLGRPEGEIVGTLRRLAAEYTGDNRGFDLRRQAGGWRYYTRESFAPYVERFVLDGQQVRLTKAALETLAVVAYKQPVTRGRISAIRGVNCDGVIRTLTTRGLIAECGTEPDTNANLYRTTALFLDKLGLNSVEELPPLAPFLPDDVNEIGEADDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q528</accession>
    <name>D3Q528_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="9">CTP synthetase</shortName>
            <shortName evidence="9">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pyrG</name>
        <name evidence="12" type="ordered locus">Snas_4432</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4432"/>
    <dbReference type="MEROPS" id="C26.964"/>
    <dbReference type="EnsemblBacteria" id="ADD44077">
        <property type="protein sequence ID" value="ADD44077"/>
        <property type="gene ID" value="Snas_4432"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4432"/>
    <dbReference type="eggNOG" id="COG0504">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011675_5_0_11"/>
    <dbReference type="OMA" id="EFNNAYR"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP_synth_N" evidence="11">
        <location>
            <begin position="27"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="333"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Amidoligase domain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="9">
        <location>
            <begin position="414"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutamine hydrolysis" evidence="9">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="545"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="547"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="38"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="179"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="219"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="498"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD44077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="587" mass="63727" checksum="2DF4D29FD366AC26" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q534</accession>
    <name>D3Q534_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadK</name>
        <name evidence="6" type="ordered locus">Snas_4438</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4438"/>
    <dbReference type="EnsemblBacteria" id="ADD44083">
        <property type="protein sequence ID" value="ADD44083"/>
        <property type="gene ID" value="Snas_4438"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4438"/>
    <dbReference type="eggNOG" id="COG0061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008831_0_0_11"/>
    <dbReference type="OMA" id="VNLGHVG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="72"/>
            <end position="73"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="146"/>
            <end position="147"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="187"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="297" mass="31585" checksum="0AF7B9A81800B522" modified="2010-04-20" version="1">MNQPRNVLLVSHTGRRDIAMEAKALVTCLRAKGFEVRALATEAGELGLDGLVAMEESRAVCDVELVLALGGDGTFLRAAELARKAAVPLLGINLGQIGFLAEAEISDISEAVSRLQRGDYVVEERLTLDAVVTLDGAEVGRDWALNESTVEKGRPARMLEVLVEVDGRRLSRYGCDGVVCATPTGSTAHAMSAGGPVVWPRVDALLLVPISAHALFSRPLVVAPDSTIAITVEPYAPAAVLTSDGRRTVAIPPGATVTVRRGEHPVRVVRLTDQPFTDRLVAKLALPVDGWRGHRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q558</accession>
    <name>D3Q558_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Prokaryotic ubiquitin-like protein Pup</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Bacterial ubiquitin-like modifier</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pup</name>
        <name evidence="7" type="ordered locus">Snas_4462</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Protein degradation; proteasomal Pup-dependent pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.</text>
    </comment>
    <comment type="PTM">
        <text evidence="5">Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the prokaryotic ubiquitin-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019678.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4462"/>
    <dbReference type="EnsemblBacteria" id="ADD44107">
        <property type="protein sequence ID" value="ADD44107"/>
        <property type="gene ID" value="Snas_4462"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4462"/>
    <dbReference type="eggNOG" id="ENOG50333JS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183816_2_0_11"/>
    <dbReference type="OMA" id="DTGGQKH"/>
    <dbReference type="OrthoDB" id="2059180at2"/>
    <dbReference type="UniPathway" id="UPA00997"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031386">
        <property type="term" value="F:protein tag"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019941">
        <property type="term" value="P:modification-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070490">
        <property type="term" value="P:protein pupylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02106">
        <property type="entry name" value="Pup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008515">
        <property type="entry name" value="Ubiquitin-like_Pup"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05639">
        <property type="entry name" value="Pup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03687">
        <property type="entry name" value="pupylate_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="ARC ATPase binding" evidence="5">
        <location>
            <begin position="28"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="modified residue" description="Deamidated glutamine" evidence="5">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="cross-link" description="Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)" evidence="5">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="71" mass="7890" checksum="90129CA72F45A6CE" modified="2010-04-20" version="1">MAEKDTGGQAHSQHAKQTTEEETTEAVVDPEIAERHEEITEDVDDLLDEIDSVLESNSSEFVRSYVQKGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q564</accession>
    <name>D3Q564_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019684.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4468"/>
    <dbReference type="EnsemblBacteria" id="ADD44113">
        <property type="protein sequence ID" value="ADD44113"/>
        <property type="gene ID" value="Snas_4468"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4468"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_762700_0_0_11"/>
    <dbReference type="OMA" id="DITIVCA"/>
    <dbReference type="OrthoDB" id="889006at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="92"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="363" mass="40731" checksum="4D3BD2B9F265CE33" modified="2010-04-20" version="1">MTSRENPALLLARRLRGLREHAWPDVSLTQRDLARVLGGSRPLSVPLISSWENPQRPVVPPAERLLAYAAFFASRRSVESRPYRLLDDAELTTVERERRDRLERELLEARSEALTFQETATTPIPVGTLDGPWRFEDGKPITIVCAEVPKQQLDSLPTPDDPLRAYAELYSYADADSLLELHGHIRAANPFSEVTVRKAPELLPDDYTTHLVLLGGSDFNSATRTLIAMLKLPVMQVPAGPESRLPTMYRVEEDGRTDDHHADWDAGGTHLLSDVGQFVRAPNPLNGKRTLTICNGIDSRGVLGTVRALVDERFRERNSAYLRDRFAGCTKYGVLTRILIVDGAVVTPDWTLKETRLHEWKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q596</accession>
    <name>D3Q596_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019716.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4500"/>
    <dbReference type="EnsemblBacteria" id="ADD44145">
        <property type="protein sequence ID" value="ADD44145"/>
        <property type="gene ID" value="Snas_4500"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4500"/>
    <dbReference type="eggNOG" id="COG1938">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055821_1_0_11"/>
    <dbReference type="OMA" id="IEPNMRW"/>
    <dbReference type="OrthoDB" id="834483at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008492">
        <property type="entry name" value="DUF774"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019151">
        <property type="entry name" value="Proteasome_assmbl_chaperone_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038389">
        <property type="entry name" value="PSMG2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09754">
        <property type="entry name" value="PAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028754">
        <property type="entry name" value="UCP028754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="282" mass="30547" checksum="8F7E2829053222B1" modified="2010-04-20" version="1">MTPTDGLPDLRSPVLVAAFTGWNDAADAASHVIAHLSEQWQAEHTATIDPDPYYDFQMARPSVKVTAEGVERVDWPYTGFSVASPTDADRDVVLLTGAEPSMHWRGFCAEVAEICHSLGVEQVILLGSLMADVGYTRPLPVSGTTNDPALAKRMKMDPVDYEGPAGIIAVLQATFQEAGVPVTSCWVHVPHYAATSPCPKATLGLLHRVEELLDLPVPAGGLVEQTAQWENDVTQLVEADSDIADYISSLDEPQAGDEPSGDDIAKDFERYLRRRGPHTDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q613</accession>
    <name>D3Q613_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0598"/>
    <dbReference type="EnsemblBacteria" id="ADD40312">
        <property type="protein sequence ID" value="ADD40312"/>
        <property type="gene ID" value="Snas_0598"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0598"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014914_0_0_11"/>
    <dbReference type="OMA" id="VYYRYGP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="215"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="864" mass="92583" checksum="A127827AC3700BB3" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q658</accession>
    <name>D3Q658_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyoxalase-like_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017804.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2552"/>
    <dbReference type="EnsemblBacteria" id="ADD42233">
        <property type="protein sequence ID" value="ADD42233"/>
        <property type="gene ID" value="Snas_2552"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2552"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1146638_0_0_11"/>
    <dbReference type="OMA" id="DHLLHCV"/>
    <dbReference type="OrthoDB" id="1515834at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025870">
        <property type="entry name" value="Glyoxalase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13468">
        <property type="entry name" value="Glyoxalase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase-like_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="242" mass="26133" checksum="0E739B69F7D7C3A4" modified="2010-04-20" version="1">MTESPAFDHLLHCVPDVEATVAKYSAAGLPAHANEPFEGFHNGAWLLDVRYVEILTIVDRELFAPSAFGKATTGWMPTIDRLMGDGGGALNFAVNVTDVDATAERLRRQGHDVEVTTFSFDGSPVSFREAILTDAPPWAPFFITYTPSREEIWTKLAADRVNRGTHDLTGIVIETPRPDEAATWLSELTGVPRDEDTAAVPLPGATVHFVPGEADQITTLLLAEGNPPTTTVDGLALRPATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q696</accession>
    <name>D3Q696_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpe</name>
        <name evidence="15" type="ordered locus">Snas_2592</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2592"/>
    <dbReference type="EnsemblBacteria" id="ADD42271">
        <property type="protein sequence ID" value="ADD42271"/>
        <property type="gene ID" value="Snas_2592"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2592"/>
    <dbReference type="eggNOG" id="COG0036">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054856_2_1_11"/>
    <dbReference type="OMA" id="WLQVDGG"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="138"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="171"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="14">
        <location>
            <begin position="193"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD42271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="219" mass="22997" checksum="91696795DDFE1858" modified="2010-04-20" version="1">MIAPSLLAADFARLAEACSAVSEDADWLHVDVMDNHFVPNLTIGTPVVKSLKAATDLPLDCHLMITDPKRWAVGYAELGAYNVSFHAEACDDPVGLARDLRAAGTKAGLAIDRDTLIEPYLDMLPEFDTLLIMTIKAGFGGQAFMPELLDKVRTARNAVESGHLELRIEVDGGIADDTIAAAAEAGADAFVAGTAVYGAADPAAAIQRLRALAAHVGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6B5</accession>
    <name>D3Q6B5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2611</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017861.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2611"/>
    <dbReference type="EnsemblBacteria" id="ADD42290">
        <property type="protein sequence ID" value="ADD42290"/>
        <property type="gene ID" value="Snas_2611"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2611"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078424_1_0_11"/>
    <dbReference type="OMA" id="GYWFLQY"/>
    <dbReference type="OrthoDB" id="1557390at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="6">
        <location>
            <begin position="36"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="271" mass="28839" checksum="637BD3C0EDCB0B45" modified="2010-04-20" version="1">MSEALVARRSVGWLSILAAEVRKGLTSQLAHPLGHVISLVVGMTMYLGLQFVLGQGQLRADLLPQTLIAIGGYWFLQYSALVMVSDLVEEKNAGTFAQSQMSTAPPWLLMVGRLVTASVFGLVVAVAASAVPAAIAGIAIPWRWAALVPYALLLIGILAFTYILAAVAIRTPMVGVLQSLFTALILLLNGAFLPLSLYPEWLAAVARLLPTTMGIEAVNEVLFDGATLARLWTSGSLPLLVVHTAVLVGIGAVLFSRNHRRAVRDGSLGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6D8</accession>
    <name>D3Q6D8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2636</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017884.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2636"/>
    <dbReference type="EnsemblBacteria" id="ADD42313">
        <property type="protein sequence ID" value="ADD42313"/>
        <property type="gene ID" value="Snas_2636"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2636"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1474">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="HQQCHDI"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098542">
        <property type="term" value="P:defense response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="19"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="BTAD" evidence="5">
        <location>
            <begin position="102"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="294"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="715"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="835"/>
            <end position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="928" mass="101062" checksum="D7F06127E7B5DD3B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6F0</accession>
    <name>D3Q6F0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4549</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4549"/>
    <dbReference type="EnsemblBacteria" id="ADD44193">
        <property type="protein sequence ID" value="ADD44193"/>
        <property type="gene ID" value="Snas_4549"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4549"/>
    <dbReference type="eggNOG" id="ENOG5034500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1348254_0_0_11"/>
    <dbReference type="OMA" id="GGACILW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049721" evidence="2">
        <location>
            <begin position="31"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="20625" checksum="87909DBEE97C604E" modified="2010-04-20" version="1">MRSLKVGVATAALAAVAVTSGCGLIGDAGAKESSDATPSDAASSTPGKDSGSASPTGEAAEAGGICEYLDFASLKKATGQAFTIAEAGGSEVVNSCVIQTTEGSFPDVTLTKAKTATDAKTYEKEIPPKDHDEVKDLGKAAYSAVRKPVEKSGPVVEIGWLTKGHMYSLRYTTVSNTASAEADAAVDALVDVARDIYKASGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6S4</accession>
    <name>D3Q6S4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF418 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0609</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
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    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ADD40323">
        <property type="protein sequence ID" value="ADD40323"/>
        <property type="gene ID" value="Snas_0609"/>
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    <dbReference type="KEGG" id="sna:Snas_0609"/>
    <dbReference type="eggNOG" id="COG2311">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_356348_0_0_11"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
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        <property type="entry name" value="DUF6350"/>
    </dbReference>
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        <property type="entry name" value="DUF418"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF6350"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
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        <location>
            <begin position="102"/>
            <end position="122"/>
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    </feature>
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        <location>
            <begin position="142"/>
            <end position="175"/>
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    </feature>
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        <location>
            <begin position="226"/>
            <end position="245"/>
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        <location>
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            <end position="287"/>
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        <location>
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        <location>
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        <location>
            <begin position="473"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="514"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="584"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="620"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="689"/>
            <end position="710"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="717"/>
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        <location>
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            <end position="781"/>
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    </feature>
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        <location>
            <begin position="196"/>
            <end position="333"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
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        <source>
            <dbReference type="Pfam" id="PF04235"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ADD40323.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="787" mass="82704" checksum="9308A382377E9E84" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6T2</accession>
    <name>D3Q6T2_STANL</name>
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        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ordered locus">Snas_0617</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
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                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <location>
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            <end position="35"/>
        </location>
    </feature>
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            <begin position="93"/>
            <end position="476"/>
        </location>
    </feature>
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        <source>
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        </source>
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        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="596" mass="66681" checksum="F1E2B739F95D62FC" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q702</accession>
    <name>D3Q702_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="10">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Isoleucyl-tRNA synthetase</fullName>
            <shortName evidence="10">IleRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ileS</name>
        <name evidence="14" type="ordered locus">Snas_0688</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015972.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0688"/>
    <dbReference type="EnsemblBacteria" id="ADD40401">
        <property type="protein sequence ID" value="ADD40401"/>
        <property type="gene ID" value="Snas_0688"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0688"/>
    <dbReference type="eggNOG" id="COG0060">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001493_1_1_11"/>
    <dbReference type="OMA" id="KMMAPFT"/>
    <dbReference type="OrthoDB" id="32262at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07961">
        <property type="entry name" value="Anticodon_Ia_Ile_ABEc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02003">
        <property type="entry name" value="Ile_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033709">
        <property type="entry name" value="Anticodon_Ile_ABEc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="PTHR42780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="12">
        <location>
            <begin position="26"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="13">
        <location>
            <begin position="705"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="10">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="10">
        <location>
            <begin position="614"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="617"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD40401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1048" mass="117615" checksum="9B71D69F4C83E83F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q704</accession>
    <name>D3Q704_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015974.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0690"/>
    <dbReference type="EnsemblBacteria" id="ADD40403">
        <property type="protein sequence ID" value="ADD40403"/>
        <property type="gene ID" value="Snas_0690"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0690"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036302_1_1_11"/>
    <dbReference type="OMA" id="AANPTTC"/>
    <dbReference type="OrthoDB" id="311112at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007795">
        <property type="entry name" value="T7SS_EccB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044857">
        <property type="entry name" value="T7SS_EccB_R1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40765">
        <property type="entry name" value="PTHR40765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05108">
        <property type="entry name" value="T7SS_ESX1_EccB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03919">
        <property type="entry name" value="T7SS_EccB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="487" mass="51200" checksum="E4BCE3912C331519" modified="2010-04-20" version="1">MATRRDQLQSYQFLLQRIVSALVYRKTDPAESPFRRAGGAIFAGVMLSILALAVTAVIGLFATGCGRTANWKDGAAIIKEEETGAFYVILPRKDEKKADQKQVLYETANFASAALIAGTTEVFEIKAQSLRSDDDSVSMGPRVGIPGAPNSIPKADALSGDDWTLCSFPADKNNDTPTSKLYIGTAKTKGDALGKDALLAKAGEEQYLVSQGHKYPISDDAIGYLNATGETVHEADKAVLDGVESGEPLEAPDYGDPKDESTTGDPVGTVYKNTGGGNTTFWVATKDNIASITELQAYLITEGSEDKFKEANTSEFSDDPDDLKPAEESSPLEKLPEFADAADESRLCAVFPSEGKETKIVYNADTPDIDGVGTPEVKEGGAALADQIVVAPGTGALVETGDSEDEGGLSLVTASGEIFGIEQTDHSGSKNGAAAPADALTAFGYRGDNSKGIKAPARVHMPSQVLSLIPRGPDLSPDSAMETVGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q740</accession>
    <name>D3Q740_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Threonine ammonia-lyase</fullName>
            <ecNumber evidence="4">4.3.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0727</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0727"/>
    <dbReference type="EnsemblBacteria" id="ADD40439">
        <property type="protein sequence ID" value="ADD40439"/>
        <property type="gene ID" value="Snas_0727"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0727"/>
    <dbReference type="eggNOG" id="COG1171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021152_4_1_11"/>
    <dbReference type="OMA" id="LIHPFDH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:L-threonine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901607">
        <property type="term" value="P:alpha-amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04886">
        <property type="entry name" value="ACT_ThrD-II-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044561">
        <property type="entry name" value="ACT_ThrD-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005789">
        <property type="entry name" value="Thr_deHydtase_catblc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01127">
        <property type="entry name" value="ilvA_1Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="6">
        <location>
            <begin position="332"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="411" mass="42542" checksum="A181D16BDB9E6A5D" modified="2010-04-20" version="1">MITSMTSLVTVDEVFAARKALSGFARVTPMEPSRGMDSVPGPVYFKCENLQRAGSYKVRGAYVRISRLSKAERARGVVAASAGNHAQGVAVAAAELGAAATVFMPSGAPLPKVAATRGYGARVELVGSTVEDCLAAAREHSEATGAVFIHPFDHPDVIAGQGTVACEIFEQCPEVKTIVAGVGGGGLISGIGVAAKALRPEVKVIGVQAEQAAAMPPSLRAGRPVRLSSYATIADGIKVGRPGEVTFPHVRDLVDDVVTVSEEDITQAVLVLLERNKLLVEPAGVVGAAALLSGVLAAEPPTVVVLSGGNIDPLLLLRLIEHGLAASGRFLRFTVRCSDVPGVLASMLGLIAERGGNVIDVMHQRYDRGHYVGEVTVALSVETRGDDHAAHLLSALKDAGYAVTMQGSGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7D8</accession>
    <name>D3Q7D8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2733</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017980.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2733"/>
    <dbReference type="EnsemblBacteria" id="ADD42409">
        <property type="protein sequence ID" value="ADD42409"/>
        <property type="gene ID" value="Snas_2733"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2733"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_2_4_11"/>
    <dbReference type="OMA" id="YDKITVG"/>
    <dbReference type="OrthoDB" id="534010at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048711" evidence="2">
        <location>
            <begin position="29"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="434" mass="46017" checksum="C247F6C2D557B3D3" modified="2010-04-20" version="1">MSLRIRATAVGLAAAVVLAGCGGGTSPAAPVKNVDADKLNGEITVWSWDVAATALNRLAEDFEKQTDVKVKVVDIGYDNAADKTSVGLKSGNGLPDVVTVETQQMQSYIGQFPKGFAEMTDAAKKYEDDMDPSKWAASSSQDGKLFGLPWDAGTAGLFYRTDYFDEAGVDPESVETWDDLIEAGKKVKKATGAKLLVSDVSGSSSLVPLLMQQQGAGYFSQDGDITLDSPEAKKALDIVKRLNDAGLIHNEKGWDALVRANKSGKVATEATGVWWAGTLTGEMPELKGKFGAMPLPAVESGGARTAANGGSGLAIPAQAKNPDAAWAFTKFVLTNTDNQVSMMKKDGLFPAYLPALKDEFFSADQDYFGGQPIYEMFAEQTAEIPAIAYTEDRSKADDVMKTVVPGVVLNGEDPDEELDAAADQLAGTTGRKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7L4</accession>
    <name>D3Q7L4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4713</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019927.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4713"/>
    <dbReference type="EnsemblBacteria" id="ADD44356">
        <property type="protein sequence ID" value="ADD44356"/>
        <property type="gene ID" value="Snas_4713"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4713"/>
    <dbReference type="eggNOG" id="ENOG50336W9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133846_0_0_11"/>
    <dbReference type="OMA" id="TLCLFVE"/>
    <dbReference type="OrthoDB" id="1987612at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045990">
        <property type="entry name" value="DUF5946"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19371">
        <property type="entry name" value="DUF5946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="169" mass="18852" checksum="F40F5BE91145DCB8" modified="2010-04-20" version="1">MDECPGCGFVGAADDPAPTPPADRHSSGACWGRYEELLARSYGIAAYRGVHQLVVDVYVAQHPGGDSRTEIQRLALCLMTLCLFVEDDVDVRRGAELHKRMMADRPDYFHALEPPPLRGMLTAADVLTAPDAAEHERLVRAWGEQVWRAWRPHHALIRDWNARALGPMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7M5</accession>
    <name>D3Q7M5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4725</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019938.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4725"/>
    <dbReference type="EnsemblBacteria" id="ADD44367">
        <property type="protein sequence ID" value="ADD44367"/>
        <property type="gene ID" value="Snas_4725"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4725"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_0_11"/>
    <dbReference type="OMA" id="VGHEVCA"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="143"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="23647" checksum="4A09C0495A21E76D" modified="2010-04-20" version="1">MRVVILEDHALLQEGLGLLLGTAGFEVAAAVGTVEEFAAAVDAEPPDIAVVDIRLPPTFRDEGLRAAIDARTRHPRLPILVLSQYIERVYATELLADRRGGVGYLLKNRISRVDDFIDAVHRVAAGGTALDPDVVAQLLITRGPAPLECLTPREREVLALMAEGHANTAIAAKLFLTERAISKHIGNIFRKLELPVDDSAHRRVRAVVKYLSATADPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7S9</accession>
    <name>D3Q7S9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4780"/>
    <dbReference type="EnsemblBacteria" id="ADD44421">
        <property type="protein sequence ID" value="ADD44421"/>
        <property type="gene ID" value="Snas_4780"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4780"/>
    <dbReference type="HOGENOM" id="CLU_1015301_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="274" mass="29900" checksum="AE4FDE9A71FCF037" modified="2010-04-20" version="1">MGAAVAVSIGVLAAGYIGLRSMRLFDIFLGDPMPSMASVYVALFFVFLTKGLIAVPLVSLLRDPSGAGVAEAMGDLRILDLGLDAIWLTGAVAAPVLEYNRQWMFTLREAVSKVRYPFWFRTFRWFGPMAICTIGFWAHIKLTRQELVVAWSLLILSFIAMDLNVRSGLIRAMQLYLKVRDRVIDDLKARVEGTRPPRPEPPPAPSIGLVLRWIALTVASGVAGYLALLADALGQLIATTGPVILMMVLGTVIDGVKSSIDSRASADLARMHRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q896</accession>
    <name>D3Q896_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hemerythrin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018041.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2794"/>
    <dbReference type="EnsemblBacteria" id="ADD42470">
        <property type="protein sequence ID" value="ADD42470"/>
        <property type="gene ID" value="Snas_2794"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2794"/>
    <dbReference type="HOGENOM" id="CLU_1685500_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="1">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="156" mass="17923" checksum="2199C9D31C62DA62" modified="2010-04-20" version="1">MNAVAAITHDHDDIRDLIDRIGQDEQDAEFLISQLRLRLAAHDAATETQVYRELLRESPACSELVGTRTVQHRELEAKLDNVERDLGTADFSRSLTMFSHKVASEMESEESTVLPVLRQVFTSEWLDEVGRRYELRWLAEMDARIRQRDAAQEPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8S2</accession>
    <name>D3Q8S2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4873</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020085.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4873"/>
    <dbReference type="EnsemblBacteria" id="ADD44514">
        <property type="protein sequence ID" value="ADD44514"/>
        <property type="gene ID" value="Snas_4873"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4873"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_8_11"/>
    <dbReference type="OMA" id="YFGETRI"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="125"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="125"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="228" mass="24592" checksum="D587A97FD16E815D" modified="2010-04-20" version="1">MPHILVIEDDAEVRSALMRGLGDRGHAARCAATGAAGLTEAQRHEPDLVVLDLGLPDVDGVSVLRMLRAVSRVPILVLTARDEEPQIVAALNHGADDYVVKPCGIAQLDARIRAVLRRTGGEGQPALLTVGGLEIDPAARTANLDGAALDLAAREFDLLRYLAERAGQVVSKRELLAEVWHYGYRGADKTVDVHVSWLRRKLGESAQAPRYLHTVRRVGVKLTAPQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q913</accession>
    <name>D3Q913_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Thiamine-phosphate synthase</fullName>
            <shortName evidence="9">TP synthase</shortName>
            <shortName evidence="9">TPS</shortName>
            <ecNumber evidence="9">2.5.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Thiamine-phosphate pyrophosphorylase</fullName>
            <shortName evidence="9">TMP pyrophosphorylase</shortName>
            <shortName evidence="9">TMP-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">thiE</name>
        <name evidence="13" type="ordered locus">Snas_0911</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 9">Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 10">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 9 10">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 9 10">
            <text>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+) = diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 9 11">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the thiamine-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.3" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0911"/>
    <dbReference type="EnsemblBacteria" id="ADD40622">
        <property type="protein sequence ID" value="ADD40622"/>
        <property type="gene ID" value="Snas_0911"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0911"/>
    <dbReference type="eggNOG" id="COG0352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018272_3_4_11"/>
    <dbReference type="OMA" id="IDDRVHL"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="SSF51391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="6 9 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TMP-TENI" evidence="12">
        <location>
            <begin position="11"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="THZ-P binding" evidence="9">
        <location>
            <begin position="136"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD40622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="22090" checksum="65C212508D9B6ACC" modified="2010-04-20" version="1">MDSSLPLGRLHVITDTRPGADPVRVARAALAAGAPVLQVRVADHHTDREAFDLTLTLVELCREYGATCLVNDRLHVALAVGADGGHVGAHDLPVHAARVVLGGTAVIGGTCRNPEAARALRRAGASYLGAGPAFATTTKDGLPEPIGPGAIGRIAAAVDIPVIGIGGVTAATAGELIEAGAHGVAVVGAISLAPDPYAATRELLDVVERAARQRGRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q981</accession>
    <name>D3Q981_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">L-arabinose isomerase</fullName>
            <ecNumber evidence="8">5.3.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2888</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.4" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2888"/>
    <dbReference type="EnsemblBacteria" id="ADD42563">
        <property type="protein sequence ID" value="ADD42563"/>
        <property type="gene ID" value="Snas_2888"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2888"/>
    <dbReference type="eggNOG" id="COG2160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045663_0_0_11"/>
    <dbReference type="OMA" id="HMLEICP"/>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008733">
        <property type="term" value="F:L-arabinose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019568">
        <property type="term" value="P:arabinose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024664">
        <property type="entry name" value="Ara_Isoase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038583">
        <property type="entry name" value="AraA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004216">
        <property type="entry name" value="Fuc/Ara_isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009015">
        <property type="entry name" value="Fucose_isomerase_N/cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003762">
        <property type="entry name" value="Lara_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38464">
        <property type="entry name" value="PTHR38464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11762">
        <property type="entry name" value="Arabinose_Iso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02610">
        <property type="entry name" value="Arabinose_Isome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001478">
        <property type="entry name" value="L-ara_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50443">
        <property type="entry name" value="SSF50443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53743">
        <property type="entry name" value="SSF53743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0054">Arabinose catabolism</keyword>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arabinose_Iso_C" evidence="7">
        <location>
            <begin position="342"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="452" mass="49774" checksum="32664AE6A93E082D" modified="2010-04-20" version="1">MQDLYDHMIPGITERQGRYAADIAHRLSEHADFEVAPPVKDRADAESAMRRFADSDLDGVLVTMLTYGPAMRVARLFNENRMPVCLANIQPEAAVTPAWDMADMTYNQGIHGAQDTANAMVRAGRRFAVITEDWRSADFAVRFDRWARAASAVTAWRSLKIGVFGYAMNDMGDIRVDENALLRTLGPEISAIAPGELWRGMRAVTDEAIAALRAFEDERFEIDPKLSDEERDDHARMQLAIESILVDGGYAAYSTHFDAIGEDGRFDRLPLAAASSLMAAGYGYGAEGDAMAAAMVHAGHQLIGDGHFTEMYAMDFPSESILMSHMGEGNWRIARDDEPVRLIKRPLGIGKLADPPTFLFRYQPGPATLASLVSLGGNRFRLVVSEGEVLDGQVLPALEMPYGQFAPTSGLRACMDGWLRAGGTHHQVMNLGHRSRDWEAFAELADIDIVHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q993</accession>
    <name>D3Q993_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018146.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2900"/>
    <dbReference type="EnsemblBacteria" id="ADD42575">
        <property type="protein sequence ID" value="ADD42575"/>
        <property type="gene ID" value="Snas_2900"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2900"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_3_1_11"/>
    <dbReference type="OMA" id="FARMGHW"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="209" mass="21882" checksum="04E641237C04DDD6" modified="2010-04-20" version="1">MPIDVALLAAFTVTTLVAMITPGPDMLFVLGCGMRGGPRAGLLATAGVAVSEAVHVIVAAAGLAALFTAVPTAFTVVRFAGAAYLIYLGVQMIRNRRKGSDEMAVGGGMLGRRAFVSGLLTNLLNPKMVTFTIAFLPQFIDPSLGNVWAQFAILGTVLIVLEFIVDGTVGVLAGRIGGWLRRRQAAKRRIDTATGGIFIGLGIRLAVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9C3</accession>
    <name>D3Q9C3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome d ubiquinol oxidase, subunit II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2930</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018176.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2930"/>
    <dbReference type="EnsemblBacteria" id="ADD42605">
        <property type="protein sequence ID" value="ADD42605"/>
        <property type="gene ID" value="Snas_2930"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2930"/>
    <dbReference type="eggNOG" id="COG1294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049294_0_1_11"/>
    <dbReference type="OrthoDB" id="761975at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="317" mass="33255" checksum="8E0461320A994C93" modified="2010-04-20" version="1">MAELFYVLLGAVFAGYFALAGYDYGVGVLLRLCGRTDTERRLILGALGPFFLGNEVWLVAGLGLLLAAFPLAEGALLTGLYPALFPLIAAIVLFTAAVQIRSRATFARPLWDLLIVGSAALISFGWGASFGLVLQGMPVRFGPLPIITGALTTALFTMHGASLLAVRTPDPIRGRAALIGSRMTFSAVVLVIAAALTAAVNAHAVNQPVIAAIGALALIAVILASQRLRRRNRPGLALIATGTAATLPMIIAAAAMYPYLYVDLDAAHSLTLTQAVAANSSLDFLLATAVPVLPVLLGFQAATWWIWRASPTKPGFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9E4</accession>
    <name>D3Q9E4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2951</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018197.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2951"/>
    <dbReference type="EnsemblBacteria" id="ADD42626">
        <property type="protein sequence ID" value="ADD42626"/>
        <property type="gene ID" value="Snas_2951"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2951"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_425723_0_0_11"/>
    <dbReference type="OrthoDB" id="642202at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048334" evidence="2">
        <location>
            <begin position="24"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="641" mass="67403" checksum="DB71E476ECB7D08F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9F8</accession>
    <name>D3Q9F8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PKD domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2965</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018211.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2965"/>
    <dbReference type="EnsemblBacteria" id="ADD42640">
        <property type="protein sequence ID" value="ADD42640"/>
        <property type="gene ID" value="Snas_2965"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2965"/>
    <dbReference type="eggNOG" id="COG2133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_294553_0_0_11"/>
    <dbReference type="OrthoDB" id="99446at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049666" evidence="2">
        <location>
            <begin position="26"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="3">
        <location>
            <begin position="372"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1029" mass="109802" checksum="6890761C882B594E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9G8</accession>
    <name>D3Q9G8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleotide-binding protein Snas_2976</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Displays ATPase and GTPase activities.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RapZ-like family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018221.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2976"/>
    <dbReference type="EnsemblBacteria" id="ADD42650">
        <property type="protein sequence ID" value="ADD42650"/>
        <property type="gene ID" value="Snas_2976"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2976"/>
    <dbReference type="eggNOG" id="COG1660">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059558_0_0_11"/>
    <dbReference type="OMA" id="TVMSFGF"/>
    <dbReference type="OrthoDB" id="1603998at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00636">
        <property type="entry name" value="RapZ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005337">
        <property type="entry name" value="RapZ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30448">
        <property type="entry name" value="PTHR30448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03668">
        <property type="entry name" value="ATP_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005052">
        <property type="entry name" value="P-loopkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="75"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="300" mass="32736" checksum="40D2771404DC9D19" modified="2010-04-20" version="1">MPDLVSPPGAERSRADLDLVIVTGTSGGGRSTVAKALENVGYYVVDNLPEALMVTMAELVFESGDATRRTAMVLDVRSHAFTADLVGAVAELKNRGFKPKVVFVDAEDDVLVRRYEKVRRAHPLQGSGRILDGIAAEREVLASARETADALIDTSNLNENQLRARVEELFAPADTRRVRITTLSFGFKHGIPLDADFVVDVRFLPNPYWIPELREHTGTESDVSKYVLSQAGADDFLATFTDLISTTVPGFEREGKRYVTIAVGCTGGKHRSVAIAEALADRLRAVGLSAYPHHRDMGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA34</accession>
    <name>D3QA34_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Substrate-binding region of ABC-type glycine betaine transport system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1036</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016317.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1036"/>
    <dbReference type="EnsemblBacteria" id="ADD40746">
        <property type="protein sequence ID" value="ADD40746"/>
        <property type="gene ID" value="Snas_1036"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1036"/>
    <dbReference type="eggNOG" id="COG1732">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_731353_0_0_11"/>
    <dbReference type="OMA" id="CPERPFC"/>
    <dbReference type="OrthoDB" id="770506at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048357" evidence="2">
        <location>
            <begin position="38"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="52"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="134"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="339" mass="34978" checksum="14DAB5DE737F70EB" modified="2010-04-20" version="1">MSPHKITRIVALPAAVAVLALGLAACGSPGSSGTKDADKVSGKGCEPVAGDSLVALEDDKKLQASENILAAFNDKAADEQAIAAVNAVSAKLTTDDLIELNKSVDVDRKSAAKTAKAFAEKNKLTKGLDKGSGSLVVGHANYTESEIVANLYAIALEGAGYTTELKDVGNRETYLPALEDNDFQVIPEYAASLTETLNPDPDADSAKNPIADNDIDKTLDTLKPFAKDAGLALSEPAEAASQNAYVVTKAFAKEHGVKTLSDFADKCSGKASSLAGPPECPKRLYCEVGLKETYGIQFGTFNSLDLGTGTKQSVASGDSTVGTVTTTDSALADGVTVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAB1</accession>
    <name>D3QAB1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase class A-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018265.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3023"/>
    <dbReference type="EnsemblBacteria" id="ADD42694">
        <property type="protein sequence ID" value="ADD42694"/>
        <property type="gene ID" value="Snas_3023"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3023"/>
    <dbReference type="eggNOG" id="COG2367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031960_9_0_11"/>
    <dbReference type="OMA" id="HYAASTM"/>
    <dbReference type="OrthoDB" id="991474at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030655">
        <property type="term" value="P:beta-lactam antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045155">
        <property type="entry name" value="Beta-lactam_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000871">
        <property type="entry name" value="Beta-lactam_class-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35333">
        <property type="entry name" value="PTHR35333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13354">
        <property type="entry name" value="Beta-lactamase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase2" evidence="1">
        <location>
            <begin position="30"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="277" mass="29894" checksum="C65BA8EE15C5F07D" modified="2010-04-20" version="1">MDALTRFDARFGALDGEFSVWCGRPGKPPVYTLEPDRLHYPASTMKIGVMAAAYRLADAGKLDLDEHIAVHNEFTSAVGGGFAMDPEYDSDAEVWQYQGASASVRWLIRRMIVRSSNLATNLVLDKVGYAAAQEAYRAAGATRSITRRGIEDYAARDAGVDNEITAADLAAQLSAIQLGRLASPASCAEMLDVLAAQEFQVDFARGLPEGTRIALKNGWIDGVRHSAALVYPDDTEPYALVACATSPLATSQEGDDEVCRIFAELSAAVWQRRADLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAB8</accession>
    <name>D3QAB8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018272.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3030"/>
    <dbReference type="EnsemblBacteria" id="ADD42701">
        <property type="protein sequence ID" value="ADD42701"/>
        <property type="gene ID" value="Snas_3030"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3030"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_14_1_11"/>
    <dbReference type="OMA" id="PADVTGY"/>
    <dbReference type="OrthoDB" id="1261526at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="305" mass="33709" checksum="2AD4F90D4519B527" modified="2010-04-20" version="1">MTQDKPLAGKVALVAGATRGSGRAFAVELARAGAIVYATGRSSDAKRSEMDRPETIEGTAAKIAEAGGTGFGVVCDHLDREQVRDLVARIESEQGRLDILVNDIWGGDHLTKWDAKLWEYDLDNGFRMMRLAIDTHIITSYYALPLLIKNPGGLVFEVTDGNTEFNAQYRDDFFYDLAKVTPMRMAFALSKELEPHGGTALALSPGWLRSEAMLDHFGVTEETWRDATKNEPHFCMSETPTYVARCLVAVASDPERHRWNGKSVASWDLAPEYGVKDADGSQPVFGPYYRDIQEPGKPADPTGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAE2</accession>
    <name>D3QAE2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 7">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplT</name>
        <name evidence="8" type="ordered locus">Snas_3054</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018296.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3054"/>
    <dbReference type="EnsemblBacteria" id="ADD42725">
        <property type="protein sequence ID" value="ADD42725"/>
        <property type="gene ID" value="Snas_3054"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3054"/>
    <dbReference type="eggNOG" id="COG0292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123265_0_0_11"/>
    <dbReference type="OMA" id="GRRKNVW"/>
    <dbReference type="OrthoDB" id="1932144at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00937">
        <property type="entry name" value="RIBOSOMAL_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="121" mass="13881" checksum="339A7E8E5966437E" modified="2010-04-20" version="1">MARVKRALNAKKKRRVVLDSAKGYRGQRSRLYRKAKEQLLHSYEYSYRDRRARKGDFRRLWITRINAAARANGITYNRFIQGLKAAEVEVDRKVLADLAVTDEAAFTALVDVARKALPATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAS4</accession>
    <name>D3QAS4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5084</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5084"/>
    <dbReference type="ESTHER" id="stanl-d3qas4">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44720">
        <property type="protein sequence ID" value="ADD44720"/>
        <property type="gene ID" value="Snas_5084"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5084"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072027_0_0_11"/>
    <dbReference type="OMA" id="LLMHGWE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="3">
        <location>
            <begin position="82"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_4" evidence="2">
        <location>
            <begin position="229"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="302" mass="32413" checksum="25CC55F9BA8425D5" modified="2010-04-20" version="1">MSASRLKKSTTVRLFQLTRLGFRIGETIAPGIASRVSTHLWFRLPASESRRRRSRVPASANRFELDSEGTTVRGWDWGSGPLVYVQHGWGGCVGDFDTIASCLVANGYRVIAVDGPSHGHSGNGPYGPRASSPLQLANALGAAIDKFGQPHAVVAHSLGCLAAVLELRERAIPKRMVMISPFIGGPTFMKMFAGWLGVGPRTFARMVASAEARIGRPMSDFSIPDPALDVDTLIVHDRRDRSTPFQHGEAIADAWPNARLVATEGLGHMRLLRSPTVAGEVVAFVTGRSAQQGEPVLGAELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAT2</accession>
    <name>D3QAT2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5093</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020299.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5093"/>
    <dbReference type="EnsemblBacteria" id="ADD44728">
        <property type="protein sequence ID" value="ADD44728"/>
        <property type="gene ID" value="Snas_5093"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5093"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_1_2_11"/>
    <dbReference type="OMA" id="EFTFDHH"/>
    <dbReference type="OrthoDB" id="2089619at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041474">
        <property type="entry name" value="NicS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17938">
        <property type="entry name" value="TetR_C_29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="19"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="233" mass="26443" checksum="B0E5B0028CEB1145" modified="2010-04-20" version="1">MPAKPRPADDEPEKQRDAERTRAEILDVATREFADNGFAGARVDEIAAKTRTTKRMLYYYFGGKKQLYLAVLERAYAGIRALESELDVDHLDPAEAVRRLAELTFDHHESHPDFIRLVSIENIHRAEHIATSTVLPSLANPALDVLTRILQRGRAAGSFRDDVDALDVHMAISAFCFFRIANRHTFRAIFDRDMLDTSRREHHRTMLGDMVVAYLTGDLGPRPAGLTQWDTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB77</accession>
    <name>D3QB77_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsJ</name>
        <name evidence="6" type="ordered locus">Snas_1184</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016465.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1184"/>
    <dbReference type="EnsemblBacteria" id="ADD40894">
        <property type="protein sequence ID" value="ADD40894"/>
        <property type="gene ID" value="Snas_1184"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1184"/>
    <dbReference type="eggNOG" id="COG0051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122625_1_3_11"/>
    <dbReference type="OMA" id="QFEIRVH"/>
    <dbReference type="OrthoDB" id="2012682at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_S10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="5">
        <location>
            <begin position="7"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="102" mass="11617" checksum="3DE810EE159A5C0D" modified="2010-04-20" version="1">MAGQKIRIRLKAYDHDVVDSSARKIVETVTRTGANIAGPVPLPTELNRFCVIRSPHKYKDSREHFEMRTHKRLIDILDPTPKTVDSLMRLDLPAGVDIEIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBE1</accession>
    <name>D3QBE1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbamoyl-phosphate synthase small chain</fullName>
            <ecNumber evidence="2">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Carbamoyl-phosphate synthetase glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">carA</name>
        <name evidence="4" type="ordered locus">Snas_3152</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CarA family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018394.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3152"/>
    <dbReference type="EnsemblBacteria" id="ADD42823">
        <property type="protein sequence ID" value="ADD42823"/>
        <property type="gene ID" value="Snas_3152"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3152"/>
    <dbReference type="eggNOG" id="COG0505">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035901_2_1_11"/>
    <dbReference type="OMA" id="CFNTGMT"/>
    <dbReference type="OrthoDB" id="662268at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="SSF52021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CPSase_sm_chain" evidence="3">
        <location>
            <begin position="5"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="CPSase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="412" mass="44168" checksum="5B2B80562862E1B2" modified="2010-04-20" version="1">MSRRAPAILVLEDGRVFHGEAFGAVGETFGEAVFATGMTGYQETLTDPSYHRQVVTMTAPHIGNTGVNETDEESPRVWVAGFVIRSAARVASNWRSQRGLEDELATQGVVGICEVDTRALTRHLRERGAMRCGISSRDTDVAALLAKVKAAPRMDGANLVDEVTCAQPYVVPANGDKKFTVAALDFGIKRNTPRRMAERGIETHVLPASSTVDDILAVKPDAVFLSNGPGDPATASGPVALVRELLSRKVPIFGICFGNQILGRALGLPTFKLKYGHRGINQPVADLETGKVEVTAHNHGFAVGLPGREHEHSAVGLPGREHEHSAVGLPGREHEHSAVGKPEGVEDRVFATDFGPAEVTHICLNDNVVEGLRLLETPAFSVQYHPEAAAGPHDADYLFDRLVRLIGEPASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBI5</accession>
    <name>D3QBI5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3197</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018438.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3197"/>
    <dbReference type="EnsemblBacteria" id="ADD42867">
        <property type="protein sequence ID" value="ADD42867"/>
        <property type="gene ID" value="Snas_3197"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3197"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_1_0_11"/>
    <dbReference type="OMA" id="FIITARV"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="103"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="328" mass="35502" checksum="A6F71754BA503CC6" modified="2010-04-20" version="1">MSHRAAATFRFVGVRLGGAAVSLLLVLVSAFFIFRVLGGDPVTAMTRDSPATPEQKAALRRELGLDKGLGAQFVDYVREMLSGRLGVSYQSRSPVVEVIWERLPATVLLTGTALVLASGVGLWIGSRAGWRAGSRFDRVHVGVSLTLWSAPTFWLGLVSVMVFGRLLGWFPVNGMRSARGSDGWLAEVVDVAHHLVLPAVTMAAVIYAQYVLVMRSSIMEEKSADYVLTARAKGLRDEVVRRRHAVPNALLPTVTLVFLQLGGVVGGAVLTETVFSWPGLGLLTYQALKIPDIPLLQGTFVFFSAAVIVANTLADIVYRMLDPRVRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBT7</accession>
    <name>D3QBT7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Abasic site processing protein</fullName>
            <ecNumber evidence="7">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_5191</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020397.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5191"/>
    <dbReference type="EnsemblBacteria" id="ADD44826">
        <property type="protein sequence ID" value="ADD44826"/>
        <property type="gene ID" value="Snas_5191"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5191"/>
    <dbReference type="eggNOG" id="COG2135">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035990_6_2_11"/>
    <dbReference type="OMA" id="FPARYNI"/>
    <dbReference type="OrthoDB" id="1718602at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:cellular response to DNA damage stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018142">
        <property type="term" value="P:protein-DNA covalent cross-linking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="PTHR13604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="SSF143081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="208"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="239" mass="26202" checksum="EA70199F3848A234" modified="2010-04-20" version="1">MCGRYVSTLSSSDLATLFEAVDDSDGEAGAGYNLAPTQTIPVVRVSRSQESRVVSAARWGLVPPWSKDPSIGVRMINARSETVATSRAYRSPFARKRCLVPANGWYEWRKLPAGGKQPYYMTAPGEDPLVFAGLWEHWGKGEESLLTCTILTTDALGGLDRIHDRMPLLLTPDRHAAWLGETESDPAELLAPPDTELVSSLEVRPVGRAVGNVRNDSPELLDRVPEPEEPTKDDEATLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC07</accession>
    <name>D3QC07_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5262</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020467.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5262"/>
    <dbReference type="EnsemblBacteria" id="ADD44896">
        <property type="protein sequence ID" value="ADD44896"/>
        <property type="gene ID" value="Snas_5262"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5262"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="MEDEQHA"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="219" mass="23078" checksum="7F4348FD1EDD5EAB" modified="2010-04-20" version="1">MADDEAMIRAGVRAILASDPDIEVVAEAADGREAVEAVRKHRPDMALLDIRMPKMDGLSAAAEIRRIAPEVGVIILTTFGEDEYIARALGDGASGFLLKSGDPRELIAGIHAVAAGAAFLSPQVAQRVIAELARGSGGGKLSRAATARTKIDKLTDREREVLALVGAGCSNAEIAKRLHVVEGTVKAYVSAILTRLEVRNRVQAAIIAYEAGLVTDDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU04</accession>
    <name>D3PU04_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phenylacetate-CoA oxygenase, PaaI subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016521.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1240"/>
    <dbReference type="EnsemblBacteria" id="ADD40950">
        <property type="protein sequence ID" value="ADD40950"/>
        <property type="gene ID" value="Snas_1240"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1240"/>
    <dbReference type="eggNOG" id="COG3396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070585_0_0_11"/>
    <dbReference type="OMA" id="NGDFAHT"/>
    <dbReference type="OrthoDB" id="1389523at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007814">
        <property type="entry name" value="PaaA_PaaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011882">
        <property type="entry name" value="PaaC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05138">
        <property type="entry name" value="PaaA_PaaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037834">
        <property type="entry name" value="PA_CoA_Oase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02158">
        <property type="entry name" value="PA_CoA_Oxy3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="233" mass="25943" checksum="1E095FF846292B70" modified="2010-04-20" version="1">MSDFDTVLGLGDDVLIAAQRLAEWTSRAHDLEEDIALSNIALDLLGQARALLTHAGHLEGAGRDEDALAFLRDDRQFRNVLLVELPRGDFATTIVRLLFLSARLWERYTRLSQGEDATLAAIAAKAVKETAYHLDHAAQWTIRLGDGTEESHARAQRAVDEQWPYTFELTGESGRQAWLDRVVPVLDKATLTRPDPDPAFRPGGGRDGLHSEHLGYLLAEMQHLHRSHPGATW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU81</accession>
    <name>D3PU81_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1318</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016598.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1318"/>
    <dbReference type="EnsemblBacteria" id="ADD41027">
        <property type="protein sequence ID" value="ADD41027"/>
        <property type="gene ID" value="Snas_1318"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1318"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_325387_0_0_11"/>
    <dbReference type="OMA" id="THENFGR"/>
    <dbReference type="OrthoDB" id="67427at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="886" mass="95596" checksum="B4E2E516BE372FD1" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV15</accession>
    <name>D3PV15_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5753 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020610.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5407"/>
    <dbReference type="EnsemblBacteria" id="ADD45039">
        <property type="protein sequence ID" value="ADD45039"/>
        <property type="gene ID" value="Snas_5407"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5407"/>
    <dbReference type="eggNOG" id="COG1426">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055817_1_1_11"/>
    <dbReference type="OMA" id="MEWGAST"/>
    <dbReference type="OrthoDB" id="1847479at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043917">
        <property type="entry name" value="DUF5753"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19054">
        <property type="entry name" value="DUF5753"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5753" evidence="1">
        <location>
            <begin position="98"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="272" mass="30648" checksum="A90024760E43E75C" modified="2010-04-20" version="1">MSSNLNPNLAKIQLGRFLKEYRLRAGLKPGDAEVVKIAKASKLKAIEAGRVQSFRYADILAFGSIYDVTRDELDNLTELQEASEKPGWYHQFDVLEAFTTFLTMESVASKLLIVEIEFITGLFQIPEYTNALREFNLENKGGADKGVKSERQELVLDGEQPPEIVYITSEAALKRQVGGRKVMKAQLEHLVTMSERPGIDILVLPFSLGPHHAMFGPFTIMYFDGGEFPTTVYLESIDGSRYEEGERFIKLYESVSDKTRKQAIPIKDYAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVC4</accession>
    <name>D3PVC4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1473</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1473"/>
    <dbReference type="EnsemblBacteria" id="ADD41177">
        <property type="protein sequence ID" value="ADD41177"/>
        <property type="gene ID" value="Snas_1473"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1473"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1348249_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="135"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="21873" checksum="AA3ECB6BA12E63D9" modified="2010-04-20" version="1">MANRETSSPIAQECPSATDEDPWMWVATAAYRVARASSYGPCPDADLRQLQVAVRAARGVGDPAPRQNTGHLVPGLTGTVTQKNGAVIPVARGYGHTMTDQPARGYGRTLTTQPGAEPRGIGPRTSAYYRGDQLPSINGKQLTVREYQILNCAAQGKSNEHIGRELFVSEHTIKTHLRRLFDKIGAANRAHAVAIAFRQGALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVF1</accession>
    <name>D3PVF1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018636.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3401"/>
    <dbReference type="EnsemblBacteria" id="ADD43065">
        <property type="protein sequence ID" value="ADD43065"/>
        <property type="gene ID" value="Snas_3401"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3401"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_4_2_11"/>
    <dbReference type="OMA" id="MGFNQGE"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="131" mass="13862" checksum="A64BFD1AC4365153" modified="2010-04-20" version="1">MERTAVNPVQWSVEMGFNQGEVVSGHTRTLYCSGQTAMSDDGKPQHDGDMAAQLALSIDNLEAVLAEADMSLANLVRLNVYTTDVDLLFQHYGVLASRLGAAGVAPTTTMLGVTRLAIPGQLIELEGTAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVI5</accession>
    <name>D3PVI5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock protein Hsp20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3435</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018670.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3435"/>
    <dbReference type="EnsemblBacteria" id="ADD43099">
        <property type="protein sequence ID" value="ADD43099"/>
        <property type="gene ID" value="Snas_3435"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3435"/>
    <dbReference type="eggNOG" id="COG0071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046737_8_2_11"/>
    <dbReference type="OMA" id="THDETHS"/>
    <dbReference type="OrthoDB" id="1523369at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="19"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="131" mass="14460" checksum="88B3DD5678DBDD92" modified="2010-04-20" version="1">MTSLTPRIFGDLADFFGMSPGSHHTPPIRIAIQQSDQEYRVRAELPGMDPNKDIHVSVDHDVLSLRAERQSGTHDETHSEFRYGSMYRAVRLPGNADTDNIKAEYVRGVLDITVPLKAGSDTSVVIPVKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVM3</accession>
    <name>D3PVM3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH ubiquinone oxidoreductase 20 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3473</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018708.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3473"/>
    <dbReference type="EnsemblBacteria" id="ADD43137">
        <property type="protein sequence ID" value="ADD43137"/>
        <property type="gene ID" value="Snas_3473"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3473"/>
    <dbReference type="eggNOG" id="COG1941">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053270_0_0_11"/>
    <dbReference type="OMA" id="GSWPEDI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037024">
        <property type="entry name" value="NiFe_Hase_small_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Oxidored_q6" evidence="2">
        <location>
            <begin position="13"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="249" mass="26563" checksum="EA1AF788311AA6FA" modified="2010-04-20" version="1">MKTSLAVWKFASCDGCQLTLLDCEDELLPLTERITIAHFLEADSSTVEGPYDVSLVEGSVTTEADVARIGRIRENSKVLVSIGACATAGGVQALRNLGDINEFASIVYARPDYIDTLATSTPIASHVEVDYELHGCPIDKGQLLEFLGALLTGRKPRLPAHSVCFECKASGTTCLMVAEGRPCLGPVTRAGCGAICPRYSRGCFGCFGPAPGANTPALRHQLTQLGMPAVHQDRVLRTFTPEAYDDAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVN9</accession>
    <name>D3PVN9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3490"/>
    <dbReference type="EnsemblBacteria" id="ADD43153">
        <property type="protein sequence ID" value="ADD43153"/>
        <property type="gene ID" value="Snas_3490"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3490"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063440_10_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="36"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="108" mass="12001" checksum="5F824138D978F15D" modified="2010-04-20" version="1">MPEKVRITPIVASLLAVMLTEPSAEHYGLDLVRRTGLSAGTIYPVLMRLRKAEWVEATWEQIDPHEAGRPARRYYRLTAHGATAARTELEAMFRKLSIVPGITGEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVT7</accession>
    <name>D3PVT7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020629.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45058">
        <property type="protein sequence ID" value="ADD45058"/>
        <property type="gene ID" value="Snas_5426"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5426"/>
    <dbReference type="HOGENOM" id="CLU_1502583_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="179" mass="19890" checksum="8041F55E869FA3D9" modified="2010-04-20" version="1">MVAFLTNRSLHRSGAKERASGRSLDACIDFVGISLHYLTVTQEYIVELASVPNTPGGEEGAGLTDDIPTMRRNISSLDKEYLIAAVRAESFAPTQSVFSFIHTAQECQSEMKDLLNKSWSRNPPVDWDATRRGVAMRHDAAAQDMTEQLRLYGAQHTYLDSFPGKSSRPESEIERTPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVZ5</accession>
    <name>D3PVZ5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5485"/>
    <dbReference type="EnsemblBacteria" id="ADD45116">
        <property type="protein sequence ID" value="ADD45116"/>
        <property type="gene ID" value="Snas_5485"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5485"/>
    <dbReference type="HOGENOM" id="CLU_936613_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="297" mass="30230" checksum="2A4DF1050A94B82A" modified="2010-04-20" version="1">MTGPYQPPGGDFNSPFGPPDPNSPFTPAPGSQGGDSQGSKDEDESSPYEGVQYELETPGQPPMTPPPHSGPPSYGPTPPPPPAYAPQPTFMPSAPPKKSNNGLLIGGVIAGVVVLLLLVGIVIFAVALGSSDGSGDDADNAKYKIPSSPCSDVDLSPVTALASFSTEPTPSSSDYGSYGSASCSGGSLGDYATSTYGYFNMYIYTYDDVAGAESMYKTDTSGLSGCETSDLSGSWDQGTLGKGSSCYYGTSGSMTVLVIQDANLEAKISLDVTEDLSSGAEDAVKSVADSLLTASKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW20</accession>
    <name>D3PW20_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5510</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020712.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5510"/>
    <dbReference type="EnsemblBacteria" id="ADD45141">
        <property type="protein sequence ID" value="ADD45141"/>
        <property type="gene ID" value="Snas_5510"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5510"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_0_0_11"/>
    <dbReference type="OMA" id="FADIPVM"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="110"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="331" mass="35796" checksum="FDF1E6B57B15EA90" modified="2010-04-20" version="1">MIRFIVRRSLLAVLTLFTISVITFALFFALPSNPAQLMCAKDCTAEQVKATEEALGLDQPLTTQYAEYMGGIFTGRTMGEGQFAKECAAPCFGYSFFTDESVWGLIKDALPITLSIAIGAWIIQTLLGIVIGIIAALRRGTVIDKLAVGSTLVGASMPVYLLGALLLLVFVYSTGIFTRPANVYEPLTENPLAWFTALILPWLSLALIGFAGEARMMRATMLETLSEDFVRTARAKGLSKSKVHRKHALRASITPVVTMSGMNLGYLLGGAAITETVFGLRGLGLQAVDSVRILNLPIVMATVLIASVFIVVMTMVVDFLYAVIDPRVRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW61</accession>
    <name>D3PW61_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1514</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1514"/>
    <dbReference type="EnsemblBacteria" id="ADD41218">
        <property type="protein sequence ID" value="ADD41218"/>
        <property type="gene ID" value="Snas_1514"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1514"/>
    <dbReference type="eggNOG" id="COG4251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002554_3_1_11"/>
    <dbReference type="OMA" id="QAEWNTP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013587">
        <property type="entry name" value="Nitrate/nitrite_sensing"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08376">
        <property type="entry name" value="NIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="566"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="818"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="877"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="895" mass="94516" checksum="2331ECE292BFCF2E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW65</accession>
    <name>D3PW65_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sel1 domain protein repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1518</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016793.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1518"/>
    <dbReference type="EnsemblBacteria" id="ADD41222">
        <property type="protein sequence ID" value="ADD41222"/>
        <property type="gene ID" value="Snas_1518"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1518"/>
    <dbReference type="eggNOG" id="COG0790">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_896644_0_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="301" mass="31738" checksum="6BFDB0BDE149B2E6" modified="2010-04-20" version="1">MTAPTHDHAAALLAAPDSTAAELLAAARDLRDAFVRGDHLIGLLPGDASDTLVAALERAGDGGEVEAWVELGRLLVYGAAPHAPYPPRDIDAAIDAFRRADAAGSRDGALGWIRVAYFTRDAERAQAAAARLDRLVAEVPDDGEVLLFKGYLTHQGYGYEHDPAAGAAWHRKAADLGNAAAAFELSVLHTTGDGLPVDETEARRWTHRAAELGSARAMANLGSMYATASGVALDGRAALDWYVKAAEAGHETAAFKAGVMCLIGDAGLPVDTKRAAELFELAEESDIDVDEELEFMGLSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW86</accession>
    <name>D3PW86_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MoaD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016814.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1540"/>
    <dbReference type="EnsemblBacteria" id="ADD41243">
        <property type="protein sequence ID" value="ADD41243"/>
        <property type="gene ID" value="Snas_1540"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1540"/>
    <dbReference type="eggNOG" id="COG1977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114601_1_0_11"/>
    <dbReference type="OMA" id="CPGIKAR"/>
    <dbReference type="OrthoDB" id="1995573at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010038">
        <property type="entry name" value="MoaD_arc-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01687">
        <property type="entry name" value="moaD_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="91" mass="9856" checksum="D059C954DAC2364C" modified="2010-04-20" version="1">MSIEVRIPTILRQHTGGQKVVSGSGDTIDELFTNLDAEHTGLRKRVVTDEGKLQKFVNVYVNDEDVRFIDGLTTKLSDGDSVTILPAVAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWE4</accession>
    <name>D3PWE4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016872.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1598"/>
    <dbReference type="EnsemblBacteria" id="ADD41301">
        <property type="protein sequence ID" value="ADD41301"/>
        <property type="gene ID" value="Snas_1598"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1598"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065153_0_0_11"/>
    <dbReference type="OMA" id="RQESANP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="267" mass="28609" checksum="2028B0B22A4D3F40" modified="2010-04-20" version="1">MSDIETLGARVRGIAAELPVPDTQKAEQRLAEAHAGLSSALRESVEPAGIPQLARAREHVSKAMAVLSTASDNLDEYLISIGLNTAGNINESTSPDETVPVEVAPGSADWWRERVNTISEGDAKTEPGEVTVTRLFSELVERARRGDRDGYRDRLLVAGAGNGSKLPGLSWPLIRNLTADILGHAPTPKDDDRLRGLVRDPVRRLLPKLPEDVTLSQLHGACSLPHVAKDSEGRETDEKPHPADTAATGPAIVAALLSAREKVKGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWS8</accession>
    <name>D3PWS8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018871.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3642"/>
    <dbReference type="ESTHER" id="stanl-d3pws8">
        <property type="family name" value="Proline_iminopeptidase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43300">
        <property type="protein sequence ID" value="ADD43300"/>
        <property type="gene ID" value="Snas_3642"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3642"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024518_2_0_11"/>
    <dbReference type="OMA" id="AHYARYP"/>
    <dbReference type="OrthoDB" id="665798at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="48"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="412" mass="46505" checksum="6FCC01471C1B6BFA" modified="2010-04-20" version="1">MSATFHIPGLILTEHEFQVPLDHSRPDGQRITVFAREVADPKGRDRPFLVFLQGGPGQEAPRPHGVPYQPGWLDRALADYRVLMLDQRGTGRSTPVGDLAGMTPQEQADYLTHFRADAIVRDAEWIRAALGVDSWSVLGQSFGGFCCLNYLSQAPEGLREVFFTGGVPPVGRHPDDVYRNTYVTMRERNRRYYQRYPGDRDRVAAIVDRLEAGDLRLPDGDVLTARRFRQIGNMLGMSDGAERLHYIVERDPDSPAFRHDVAAAMPFSGRNPLYAVIHESSYADGHATRWSAQRTLPADFESDQTLFTGEHVYSWMFTDYRELAPLREAAEILAEHEWPVLYDAERLRACEVPCAAAIYAEDAYVDRVYSEETAALIPTMRSWLTNEFEHNGLRAAGDRVLDRLIALTNGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWT1</accession>
    <name>D3PWT1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MMPL domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3645</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3645"/>
    <dbReference type="EnsemblBacteria" id="ADD43303">
        <property type="protein sequence ID" value="ADD43303"/>
        <property type="gene ID" value="Snas_3645"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3645"/>
    <dbReference type="eggNOG" id="COG2409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005108_1_1_11"/>
    <dbReference type="OMA" id="GMRTWPQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="496"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="525"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="563"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="608"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="634"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="194"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="711" mass="74158" checksum="2DEB7F147BF28DAD" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWV0</accession>
    <name>D3PWV0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phytanoyl-CoA dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5543</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020745.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5543"/>
    <dbReference type="EnsemblBacteria" id="ADD45174">
        <property type="protein sequence ID" value="ADD45174"/>
        <property type="gene ID" value="Snas_5543"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5543"/>
    <dbReference type="eggNOG" id="COG5285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048953_6_0_11"/>
    <dbReference type="OMA" id="DMSLPRE"/>
    <dbReference type="OrthoDB" id="1070946at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="282" mass="31539" checksum="447491982D19E1F5" modified="2010-04-20" version="1">MTQTTVSRSYKQRFDEDGYVVVSGLFSGAEVDRLREHYMALRRRGPLPDDLVGVKASSRDPLRRYPRMAQMHRWDDTTRDWLLDPRLARQLSELLGAEPYAVQSMLYFKPAGSRGQALHQDNFYLRAEPGTCVAAWMALDDTDEENGCMKVVPGSQDWPMLCTAKADTRLSFTDVTVPLLAEQRVDAVHMKPGDVLFFNGSVVHGSHPNTSADRFRRALIGHYIQAEATQVAQYYHPALRMDGTPLELTVAEGGGACGEWAEESGQPVIAMTGHEAVTRKHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWV5</accession>
    <name>D3PWV5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="8">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">argS</name>
        <name evidence="12" type="ordered locus">Snas_5548</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020750.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5548"/>
    <dbReference type="EnsemblBacteria" id="ADD45179">
        <property type="protein sequence ID" value="ADD45179"/>
        <property type="gene ID" value="Snas_5548"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5548"/>
    <dbReference type="eggNOG" id="COG0018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006406_0_1_11"/>
    <dbReference type="OMA" id="NKPLHLG"/>
    <dbReference type="OrthoDB" id="1146366at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="11">
        <location>
            <begin position="4"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="10">
        <location>
            <begin position="428"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD45179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="550" mass="59294" checksum="856BDD07EE98DD67" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX16</accession>
    <name>D3PX16_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020811.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5610"/>
    <dbReference type="EnsemblBacteria" id="ADD45240">
        <property type="protein sequence ID" value="ADD45240"/>
        <property type="gene ID" value="Snas_5610"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5610"/>
    <dbReference type="eggNOG" id="ENOG50348RK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_745211_0_0_11"/>
    <dbReference type="OMA" id="TEGRHPL"/>
    <dbReference type="OrthoDB" id="2097694at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="347" mass="36953" checksum="EA058673E1F1DF34" modified="2010-04-20" version="1">MREATEVNDASTLERRYRRLLRAYPPDYRRERGEEMLTTLVDAAEARDRAPVGEDAMLVLRGLRLRLTAGTTSARVMAVLAAIIIGVLGAAGGALAGWQNASGLPDQDAAARIADTAVPGAKAAESRDVLFGWGSTDASMLHLGGDDYGAGFRGFAVEHVNDERRLLKQANRNLTAAGWDVEPLAATEYGTEFTATRDGLLVTVRTDGDATASSTTSVHIERAQPPTVLVLAAAGLILGAILGWAVIVWLEQLMAHWGGVRKSILAGPLTVAALALGLPTLFNLYMLALAVASPSRPTPVWLGYVWGPPGLLTLFGIAALAYGLWKVLAAMLRRPERVPVSRERVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX19</accession>
    <name>D3PX19_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyruvate phosphate dikinase PEP/pyruvate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020814.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5613"/>
    <dbReference type="EnsemblBacteria" id="ADD45243">
        <property type="protein sequence ID" value="ADD45243"/>
        <property type="gene ID" value="Snas_5613"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5613"/>
    <dbReference type="eggNOG" id="COG0574">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3848">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005950_0_0_11"/>
    <dbReference type="OMA" id="WRSVKSH"/>
    <dbReference type="OrthoDB" id="997616at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="2">
        <location>
            <begin position="22"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="1">
        <location>
            <begin position="792"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="873" mass="93648" checksum="D34E599CD5F49683" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX28</accession>
    <name>D3PX28_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5622</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020823.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5622"/>
    <dbReference type="ESTHER" id="stanl-d3px28">
        <property type="family name" value="Carb_B_Bacteria"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45252">
        <property type="protein sequence ID" value="ADD45252"/>
        <property type="gene ID" value="Snas_5622"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5622"/>
    <dbReference type="eggNOG" id="COG2272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_13_0_11"/>
    <dbReference type="OMA" id="KWFDLHR"/>
    <dbReference type="OrthoDB" id="489066at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005126347" description="Carboxylic ester hydrolase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="COesterase" evidence="3">
        <location>
            <begin position="36"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="521" mass="56719" checksum="3381A72A2E0229E0" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX54</accession>
    <name>D3PX54_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4097 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5648</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020849.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5648"/>
    <dbReference type="EnsemblBacteria" id="ADD45278">
        <property type="protein sequence ID" value="ADD45278"/>
        <property type="gene ID" value="Snas_5648"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5648"/>
    <dbReference type="eggNOG" id="COG3595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076844_2_0_11"/>
    <dbReference type="OMA" id="EMHARAD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049526" description="DUF4097 domain-containing protein" evidence="1">
        <location>
            <begin position="35"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4097" evidence="2">
        <location>
            <begin position="135"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="269" mass="28487" checksum="3AE509D0664784AB" modified="2010-04-20" version="1">MSEVEYRKPRSRGAVRLIVFLAVVVVLTAGGVFAWKFLFNGPKHKDEQTKTYDETITRLDVEGNSGNVDIVAGEGDEIEVETTLEWRGKEKPGADQDVTGKTLKVTATGCEGIDLFGGLTCEVHFRIAVPADIDLKAEVDSGNLTVAGIKGEQNLACDSGDIEVEGSGEKLTVHADSGNVVGRELDATTVKADVDSGDVELEFTTAPKKTRASADSGDVTLSVPKVKEGYDVNIGVDSGDKSVEVKTASDSPRKIDGTVDSGDFTVAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY07</accession>
    <name>D3PY07_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020907.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45336">
        <property type="protein sequence ID" value="ADD45336"/>
        <property type="gene ID" value="Snas_5706"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5706"/>
    <dbReference type="eggNOG" id="ENOG502ZSUD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_962811_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="289" mass="29675" checksum="78A495360908DFAB" modified="2010-04-20" version="1">MRDPRVVAVCSAGILAALLGIGQLLAADLTGILFSRGGVRATAQDTVDESAIVIWIAAVAVCLAAAAPRIFLKSVPGHRMRWVLSGAAAFGALLAAPVATAIASWAQVYGSELSQSRVLRLVCLGVVLGAVVSAAAVRSKPAAWSLISWVGVVWVLLLVSVRTSPGATPLISHLDPGPQWSSGNRFLQGSLLLLMVAVLCGAALGVAGIKLRWGRDMRRCRSAIALMSVAGPLVVLVAYLTAGVAGGDWNGGHVLNLTAASVLIATGYWAGACLTKRLRRDGPAGTMSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYE3</accession>
    <name>D3PYE3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1814</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017081.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1814"/>
    <dbReference type="EnsemblBacteria" id="ADD41510">
        <property type="protein sequence ID" value="ADD41510"/>
        <property type="gene ID" value="Snas_1814"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1814"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_7_3_11"/>
    <dbReference type="OMA" id="GSYFKEP"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="133" mass="14202" checksum="E392C427BD9E97D9" modified="2010-04-20" version="1">MSNKTAVTTDAAPAPAHTFSQGVRKGPILQVSGQGPVDPASGEYLYPGDVKAQTTRTLRNVAAIVTASGASFDDVIMLRVYLTKREDFAAMNEAYGEFLAEHVTDGVLPCRTTVFTGLPREEMLVEIDAQAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYY8</accession>
    <name>D3PYY8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020988.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5787"/>
    <dbReference type="EnsemblBacteria" id="ADD45417">
        <property type="protein sequence ID" value="ADD45417"/>
        <property type="gene ID" value="Snas_5787"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5787"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_15_11"/>
    <dbReference type="OMA" id="ICTLAVE"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="318"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="415" mass="44912" checksum="6DC4BB06B8F8B90A" modified="2010-04-20" version="1">MNTDRDGVGGRRWVRVNNGRAPLFLSGLFYFAVALLLTSSALDLGFLRLDIPASGGSEPLNAWGFLAATVVAAVVWPLLRWSRDGGRFTKLASVVFVAAVTLLLSVGGWAAIVLEAMVTVHIVFAFGLRFALGYVVALAVTSFGISWWYRGSVAIAVIETAISVVFALWAIAMAKVLQSEQRQAEQTRRLLAERTEAHEELRRYAARVKELTVSEERARMSREMHDSVGHYLTVISLGLRNAQRYREAGVGDAWAEVAQARQLTTEALEETRRWVKALRPLALEDRAGPAAMAALAESFSGFEVDFQAGDGLPELDENVELLLYRSLQEGLANVARHSGATRVTVRLSGDERSVRLSITDDGRGADPDRADGFGLAGLRQRAEAAGGTVATSRPDTGGFTLTIEAPTAPRPAMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZN9</accession>
    <name>D3PZN9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019147.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3921"/>
    <dbReference type="EnsemblBacteria" id="ADD43576">
        <property type="protein sequence ID" value="ADD43576"/>
        <property type="gene ID" value="Snas_3921"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3921"/>
    <dbReference type="HOGENOM" id="CLU_1460437_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="19484" checksum="8CC3ED5CFF400820" modified="2010-04-20" version="1">MTVTWWGWLVRQARRALSFGFGLRLGIAGSGALALWLAVPQLNHWGWYAFLIGTLPLVAALAPAKPFATLVQLQAVVMLLVNGYLVEEISPLVAIGVGVCCYLLHACAAMAALWRVDTVAESRVWQGWLARIGGVVTVSAVLAGVVVAVSGQPIEGPPALMAAAAACLALAVVSGVAWLYHRRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q008</accession>
    <name>D3Q008_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021108.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5909"/>
    <dbReference type="EnsemblBacteria" id="ADD45537">
        <property type="protein sequence ID" value="ADD45537"/>
        <property type="gene ID" value="Snas_5909"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5909"/>
    <dbReference type="eggNOG" id="ENOG503357V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048561_0_0_11"/>
    <dbReference type="OMA" id="DTVWASI"/>
    <dbReference type="OrthoDB" id="1396602at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="338" mass="36207" checksum="FA0416AD242B1805" modified="2010-04-20" version="1">MSFDMEDNAPDLTAKVATAWRDFTAALAAVLSGLPVGADLALILDPTTSGTGNAVYDVSVTVPAAGQIRADATSNATLPGTAQLGRRAVGQLVALGWQPPGVIDDSADRFALSSTAAESEELANIVARTMRDVYGAPHPAFLTYDYRDSAGIEGTELMLPPARRMPPPTEGELTDPSTAPTVPSDAGSLAEVVATVVAAMQDTTPAHLAIDDNGEISLRAGSAMVFIKPMDRPAIVDVYSPLLTEVAPNERLYRELSELTRRLPIGRLYYADGTMWASVPVYGRDFQPRHLMLAVESMTRLADELDDRLQLKFGGRRFFDQKAIEEAPEDAPPTGMYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q070</accession>
    <name>D3Q070_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-quinone oxidoreductase subunit H</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NADH dehydrogenase I subunit H</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nuoH</name>
        <name evidence="7" type="ordered locus">Snas_5972</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cell membrane</location>
            <topology evidence="5 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the complex I subunit 1 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021170.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5972"/>
    <dbReference type="EnsemblBacteria" id="ADD45599">
        <property type="protein sequence ID" value="ADD45599"/>
        <property type="gene ID" value="Snas_5972"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5972"/>
    <dbReference type="eggNOG" id="COG1005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015134_0_1_11"/>
    <dbReference type="OMA" id="MYVGMGI"/>
    <dbReference type="OrthoDB" id="1559067at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01350">
        <property type="entry name" value="NDH1_NuoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001694">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1/FPO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11432">
        <property type="entry name" value="PTHR11432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00146">
        <property type="entry name" value="NADHdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="320" mass="34725" checksum="A23E2F62C13A1EE2" modified="2010-04-20" version="1">MPVWLDLTIRLAAVVIAFLTLPLIVGQTEHKVMAHMQGRLGPMYAGAYHGWAQLIADGVKFVQKEEVAPRAADKPVFKLAPLVALFPYLVALLVIPLGPNDLVAQPLDIGLFLVLAIVGVGIVAVLMAGWASANKYTLIGAMRAAAQLLGYELPFVLAAASVAMAAGTLSLSGIVEAWNPWWLLWQAPALFVFFIAGLAEIRRPPFDAPIADSELVFGYLTEYTGLRFAFFLLAEYVGIVVIAALTTVLFLGGWQGPFLDAQLGWLWTLIKIGAVSFVVIWLRVAYPRLRVDQLQKLCWKVLVPIALGQLALTALVKVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0G8</accession>
    <name>D3Q0G8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2009</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017275.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2009"/>
    <dbReference type="EnsemblBacteria" id="ADD41704">
        <property type="protein sequence ID" value="ADD41704"/>
        <property type="gene ID" value="Snas_2009"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2009"/>
    <dbReference type="eggNOG" id="COG4225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023844_1_0_11"/>
    <dbReference type="OMA" id="PNNWNPW"/>
    <dbReference type="OrthoDB" id="442785at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012480">
        <property type="entry name" value="Hepar_II_III"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07940">
        <property type="entry name" value="Hepar_II_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="SSF48230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="581" mass="64335" checksum="23380F111749E826" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0N4</accession>
    <name>D3Q0N4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-1,2-mannosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2076</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017341.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2076"/>
    <dbReference type="CAZy" id="GH92">
        <property type="family name" value="Glycoside Hydrolase Family 92"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41770">
        <property type="protein sequence ID" value="ADD41770"/>
        <property type="gene ID" value="Snas_2076"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2076"/>
    <dbReference type="eggNOG" id="COG3537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003690_0_0_11"/>
    <dbReference type="OMA" id="DVRMGMY"/>
    <dbReference type="OrthoDB" id="100818at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="Alpha_mannosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049610" evidence="2">
        <location>
            <begin position="31"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92N" evidence="4">
        <location>
            <begin position="244"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92" evidence="3">
        <location>
            <begin position="469"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="978"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1124" mass="122373" checksum="B1CC81C8148B782F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0S5</accession>
    <name>D3Q0S5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2117</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017382.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2117"/>
    <dbReference type="EnsemblBacteria" id="ADD41811">
        <property type="protein sequence ID" value="ADD41811"/>
        <property type="gene ID" value="Snas_2117"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2117"/>
    <dbReference type="eggNOG" id="COG0742">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075826_1_0_11"/>
    <dbReference type="OMA" id="FNWLMPY"/>
    <dbReference type="OrthoDB" id="1827334at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031167">
        <property type="term" value="P:rRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00095">
        <property type="entry name" value="TIGR00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="188" mass="20187" checksum="2C180CDE1D256471" modified="2010-04-20" version="1">MTRIIGGSLGGRRLSTPEGDNTRPTSDRVREALFGSLEAAGVLDGAHVLDLYAGSGAVGLEALSRGAASALFVESHAATARVLRRNIAALGVAAETDVNTAKLPAALKQEPPRRFDLVFADPPYALDPTDLAIVLSHLVELDWLSEDADVVVEGPARGGEPFWPEGLTRDRSRRYGETILWYGHRSWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0V0</accession>
    <name>D3Q0V0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4048"/>
    <dbReference type="EnsemblBacteria" id="ADD43700">
        <property type="protein sequence ID" value="ADD43700"/>
        <property type="gene ID" value="Snas_4048"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4048"/>
    <dbReference type="eggNOG" id="COG1397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1073285_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="259" mass="28966" checksum="3FB838E01F75DB63" modified="2010-04-20" version="1">METWETTDKIYAALDRFEDAIDGWQRPAAYGILRSDGCEIEPVRVNLNEHYLPAVILATVCGHSSGTKSYDFDDVMLDRAIELLAPAGACPDFDHPNLAALRRVREHGSPSDLIGVVFVDDLDVVPADDYIRHTIGAALDGRCENPDGTTTLWRPTGPQELALVEQSGWRAWPPRLADQPIFYPVLNENYAVRIAREWNVPASGSGFVTKFHIDTPYARTLPTQRAGGNNERELWVPAERLTEFNEHIVGTIEVTHRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0V1</accession>
    <name>D3Q0V1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4049</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019272.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4049"/>
    <dbReference type="EnsemblBacteria" id="ADD43701">
        <property type="protein sequence ID" value="ADD43701"/>
        <property type="gene ID" value="Snas_4049"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4049"/>
    <dbReference type="eggNOG" id="COG2761">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087602_1_0_11"/>
    <dbReference type="OMA" id="VDGTVWF"/>
    <dbReference type="OrthoDB" id="996965at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="22805" checksum="CC2F6D31D8FB9108" modified="2010-04-20" version="1">MTQAKPVEFWFDPSCPYTWLTSRWLIEAATVRPIEIRWHIMSLAVLNEGREVDPEGDTEGYLWYPVRVCAAVERHRGKTKLAAFYTALGNRLHKDQPQWDDNVFTDALTEAGLPVELAKAATSDDLDVDVRASHERGIGLVGDHVGTPVIAATGPSDEPVAFFGPVISRIPRGEEAGRLWDLVVPLAGFDGFHELKTTAPKPPDYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0W4</accession>
    <name>D3Q0W4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carbonic anhydrase</fullName>
            <ecNumber evidence="3">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_4062</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + hydrogencarbonate = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019285.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4062"/>
    <dbReference type="EnsemblBacteria" id="ADD43714">
        <property type="protein sequence ID" value="ADD43714"/>
        <property type="gene ID" value="Snas_4062"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4062"/>
    <dbReference type="eggNOG" id="COG0288">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053879_4_2_11"/>
    <dbReference type="OMA" id="DLYVMRT"/>
    <dbReference type="OrthoDB" id="1841447at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048777" description="Carbonic anhydrase" evidence="7">
        <location>
            <begin position="35"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="233" mass="24929" checksum="D53C2A8D1463C039" modified="2010-04-20" version="1">MRLKPVHRRTLLTTAGLAVAGTAGTVALAPSAIAEDQAASPDAALDRLMRGNRRYIKGHSRHPHQSLEYLHEVAKGQHPFAITIGCADSRVPPEILFDQGLGDVFDHRIAGNIPDELLLGSIEFAIEEFAPPLLMALGHERCGAITATIDAIESGTEPPGHIAAIVEALRPVVEPVLDEPGDKVENGVRANIVDVVEQLQRRSDIVAEKVEAGELTVVGARYDLDTGKVTLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0X0</accession>
    <name>D3Q0X0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate kinase FGGY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4068</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019291.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4068"/>
    <dbReference type="EnsemblBacteria" id="ADD43720">
        <property type="protein sequence ID" value="ADD43720"/>
        <property type="gene ID" value="Snas_4068"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4068"/>
    <dbReference type="eggNOG" id="COG1070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009281_3_1_11"/>
    <dbReference type="OMA" id="WMGNRTP"/>
    <dbReference type="OrthoDB" id="1619686at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="1">
        <location>
            <begin position="1"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="2">
        <location>
            <begin position="272"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="482" mass="50384" checksum="51DDF9B2C134AB59" modified="2010-04-20" version="1">MYLGIDIGTSVTKAAAFDDDGRLVAVKGTPTRMSTPAEGFYEQDIDEVVASVAEVAAATATAAGGIPTAIGLTGQGDGVWLVDADGQAVRPAISWMDGRAASILTDWLADGTVAKAFRRTGNTMFPGSAGPILAWLDQHEPESLDRAATAGYCKDVVMQRLTGVRATDTSDASLPFLDPATRRYDPEVLEWCGIGHRASLLAPVAEPLPVGKLTDAAAARLGLPSGITVTSGPFDLPACALGSGIVTPGDGHLIIGTTLACQVLVDHVDTDVEPNGLTLATGTPNRWLRAMPAMVGTAAVDWVLKLIGRDHQALETLLADSPLGARGVTCLPFFSPAGERAPFLEPAARAGFDRVTIQTEPSDLVRATCEAVAFAARHCFEAAGLTGELAMCGGGTASPTWLKIFADVLNRPLKLAPQPETGARGAALAARRIAEPAASLSEWTTPEGVVEPDPIRAAEYEHRYAAYRARVDAARLTWKEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Z2</accession>
    <name>D3Q0Z2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <sequence length="92" mass="10468" checksum="5072DE4E5A4C86BF" modified="2010-04-20" version="1">MTSNQTTVEVEYARFTDPIRTYVITSSFTPDTIRVYAGEPRETETIVCTISNVSIHPIPAFGGLWVTNTPDWKDRFCAEAVRVYRNAVHRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q177</accession>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
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                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
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            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
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    <feature type="transmembrane region" description="Helical" evidence="3">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
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    </evidence>
    <sequence length="1652" mass="169478" checksum="2907739C26408AE4" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1C0</accession>
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        <recommendedName>
            <fullName evidence="1">Methyltransf_25 domain-containing protein</fullName>
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            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
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                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
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                <person name="Palaniappan K."/>
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                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
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        </location>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
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    </evidence>
    <sequence length="344" mass="37290" checksum="73B27E24468ACD89" modified="2010-04-20" version="1">MNAQAGGETDLYADALGHYRSPDRGDAVKVDWERPDYVGLLRVALRHVRAGRRGIRVVDLGAGAGEGWWLTRAALGRGVHFGYTAVDSSPSLLALGERRLGGEAGVRFRLTDMRDFDFAADPTDVYLSVGAPFSELDEESFAEVVRGIGMAVASRRGPSAVVLDVYGRDCLSWIPVAADRRTYSMTFFLDAASPPTRDMRFYTRGRLERVIHNGLTDAARNRLTGLVFSDRCVFSSRHTLTGAYNPDVPRLRTAVNALINGEDVPDGDRGLVIPEKAYLPHLGATPSHRALARTVDTWNKTVHTGLLGGRRSLARSLRGLNQITGTAAAGIGHYLTVVALFAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
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            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
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                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
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                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
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                <person name="Palaniappan K."/>
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                <person name="Hauser L."/>
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                <person name="Jeffries C.D."/>
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                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021283.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6088"/>
    <dbReference type="EnsemblBacteria" id="ADD45712">
        <property type="protein sequence ID" value="ADD45712"/>
        <property type="gene ID" value="Snas_6088"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6088"/>
    <dbReference type="eggNOG" id="COG4332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090982_1_0_11"/>
    <dbReference type="OMA" id="WLLVRCV"/>
    <dbReference type="OrthoDB" id="2037436at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009412">
        <property type="entry name" value="DUF1062"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06353">
        <property type="entry name" value="DUF1062"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="182" mass="20460" checksum="ABF0E51FF3191C8C" modified="2010-04-20" version="1">MLENWVVMPTRLPLIRRRCHVCASARFGPSGKFRVNANQKLIDVWLLALCTGCGETTKLTVLERTRVRAIPSGLLDRLLHDDPDLIAELLQDPAIQRRNRVCLDWEDAWRLDTGEPDRQGAEVIEVAVHFAARIPVRVERLIAEGLGLSRAEVERLTVTGNLVSAVKPSGKLSEDFTFTVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1F8</accession>
    <name>D3Q1F8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021309.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6114"/>
    <dbReference type="EnsemblBacteria" id="ADD45738">
        <property type="protein sequence ID" value="ADD45738"/>
        <property type="gene ID" value="Snas_6114"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6114"/>
    <dbReference type="eggNOG" id="ENOG5033CA0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_933541_0_0_11"/>
    <dbReference type="OMA" id="PHGWNAP"/>
    <dbReference type="OrthoDB" id="1919342at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="31469" checksum="C4F6555C0072CFD3" modified="2010-04-20" version="1">MSEAHSDTTVPPSSDPLVPRDFNEWTLNVYGIFKRSGYRIMGIVLLWSIIPVVAGVWTSSQLLRITDRLNKALPADQTTLTPAQTETMWAHVTEALSWSGIAVAVSLALSYFTAAGWAAALRVAVTDAAGKPIGFGEAMAYGARKGLSMWGWYLLVSLCAMVGACLCVLPGLYMAVAFALFAPVVVLEGGMAMARSFRLVHNAFGKMLGRIALSFAGVLSVGLVLYVLQLLIAGFGLGSDGMSPSSPLDLFADGVFALASAVLTAVILISGLLVTYAEARAREDGSATTVELLERSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1I8</accession>
    <name>D3Q1I8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acetyl-CoA acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0115</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0115"/>
    <dbReference type="EnsemblBacteria" id="ADD39836">
        <property type="protein sequence ID" value="ADD39836"/>
        <property type="gene ID" value="Snas_0115"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0115"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_2_2_11"/>
    <dbReference type="OMA" id="WGCANQA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="4">
        <location>
            <begin position="4"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="5">
        <location>
            <begin position="261"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="2">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="384" mass="40611" checksum="B57F1253E91F270C" modified="2010-04-20" version="1">MEAYLIDAVRTPFGRHAGGLSHIRTDDLAAMPIAELLRRNPDVDPASIDDVILGDTNQAGEDNRNVARMAALLADLPVTVPGVTVNRLCASGAEAIVLAARQVASGDAERVVAGGVESMSRAPFVLPRPDTAFPRNLSLVPTQVGWRLPNPKFARAWVDSLGECAQNLAAEYGIGREAQDTWALRSHLRAQDAWDKGLHAQRVMHVDGVPRDECVRADTNREKLAGLKPAFTVDGTVTAGNSSPISDGAAAVLVSRDPGENPMARLVSSATVGVSPERFAVAPVDAINKALFKAGLHFRDIAVWELNEAFSAMVLSCLHLLPEVDVNRVNPNGGAIAYGHPLGASAPRVIMDLCDQLRRRGGGYGVAAACIGVGQGMAVVVHVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1J8</accession>
    <name>D3Q1J8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0125"/>
    <dbReference type="EnsemblBacteria" id="ADD39846">
        <property type="protein sequence ID" value="ADD39846"/>
        <property type="gene ID" value="Snas_0125"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0125"/>
    <dbReference type="HOGENOM" id="CLU_930370_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048799" evidence="2">
        <location>
            <begin position="49"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="299" mass="30479" checksum="332A20505290D793" modified="2010-04-20" version="1">MTGQHRGTGERRLARLRACLTSRGLRRGLLIAGFATVAWLAGSSHANADSGPVADTELATTPLVSRALEAMTTSDETGVADEARSPDFRHASSTVDTAASETPNRVLRFTHPVTAPLAKQATPDMVAPLTSAARPVTGELDAVTKPVDGTLKRIARPVAVDANPIGAVLSWVKPTSNGTENETVRDHSDSAAAKARHGDLGANVTLDRTVPHDRNADGRTGASEPFTGTAQPDIYGIAAPGGIGTGTGPGGSPTHDTGAGLSMSAADSAVNAGTSRVNPLTAATGQLPDHVEDPAVSPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1K7</accession>
    <name>D3Q1K7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015426.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0134"/>
    <dbReference type="EnsemblBacteria" id="ADD39855">
        <property type="protein sequence ID" value="ADD39855"/>
        <property type="gene ID" value="Snas_0134"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0134"/>
    <dbReference type="eggNOG" id="ENOG503287X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2048300_0_0_11"/>
    <dbReference type="OrthoDB" id="2203671at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048801" evidence="1">
        <location>
            <begin position="29"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="120" mass="12029" checksum="DA89BE2E850B4338" modified="2010-04-20" version="1">MRKSIKALTVAAVAAGIGAFALAGTAQAGPTGADEMGMNPTGGGVSVLSDICAGNWNGPVLTGLTANNTDTRDVCSGFGGSDDAQLKLGSNLCAVNWDWNDAGKVGVINSVKDYQLCHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1K8</accession>
    <name>D3Q1K8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015427.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD39856">
        <property type="protein sequence ID" value="ADD39856"/>
        <property type="gene ID" value="Snas_0135"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0135"/>
    <dbReference type="HOGENOM" id="CLU_2791962_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048551" evidence="1">
        <location>
            <begin position="25"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="68" mass="6812" checksum="1A3BF694E82894B2" modified="2010-04-20" version="1">MKRTIAAVMLALGAAFFVATPALAEPVGQQAPTAGLGLPDPASVDLAKLPVCGLNVANQTLAPDCQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1R4</accession>
    <name>D3Q1R4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0193</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015483.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0193"/>
    <dbReference type="EnsemblBacteria" id="ADD39912">
        <property type="protein sequence ID" value="ADD39912"/>
        <property type="gene ID" value="Snas_0193"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0193"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_16_6_11"/>
    <dbReference type="OMA" id="CYRAVES"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="973"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="933"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1007"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD39912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1054" mass="109381" checksum="F91683EEFBB77A4F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1U1</accession>
    <name>D3Q1U1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015510.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0220"/>
    <dbReference type="EnsemblBacteria" id="ADD39939">
        <property type="protein sequence ID" value="ADD39939"/>
        <property type="gene ID" value="Snas_0220"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0220"/>
    <dbReference type="eggNOG" id="ENOG5034521">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_796721_0_0_11"/>
    <dbReference type="OrthoDB" id="1414873at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="348" mass="38625" checksum="B5C705E3B75E29F4" modified="2010-04-20" version="1">MPHPVLDLSSASRDVYLSPSRLSRETELIGELYALLEPQLNVLADDIEDDPDLAEAIEAVRTIAAGGRADADTAHELLTGWAEELEETGDHDDAITARIVWLVAAWLSVKVGRHLRTEAGSDPLWRFGGLVNVLALPRLGKDFREVMAAVDETGFHDAHRPAVSGEHYDRALEAVVAELSKLDSAKRLDVLYAWISPLLDEVAWENREFMDEPEMETAEAVERFRRLASGDTPDDGDEADAVHYHLTSFALGESEDQDPDMHVRSQAAYLAADWLRLKTGRQLRADENLGNYAPDDLPGLVNTLAWTRSRQISQLPEYVDELIDSGHDLLTPITELRAMLTDLTSPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q212</accession>
    <name>D3Q212_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Signal peptidase I</fullName>
            <ecNumber evidence="3 5">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2187</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the peptidase S26 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017450.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2187"/>
    <dbReference type="MEROPS" id="S26.025"/>
    <dbReference type="EnsemblBacteria" id="ADD41879">
        <property type="protein sequence ID" value="ADD41879"/>
        <property type="gene ID" value="Snas_2187"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2187"/>
    <dbReference type="eggNOG" id="COG0681">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028723_0_0_11"/>
    <dbReference type="OMA" id="ACDAYIK"/>
    <dbReference type="OrthoDB" id="1741894at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="6">
        <location>
            <begin position="37"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="261" mass="28884" checksum="A02A2C7E0133C95A" modified="2010-04-20" version="1">MWSRDHNCAYTACVIDDDSSTRAGADEPEEDKKGSFWRELPVLLAIAVVVALVVRTFALQSFWIPSGSMENTLQRGDRVLVNKLIYDFREPERGEVIVFKAPQSWRGEPGDEDFIKRVIAVGGDTVSYDAGDGQIAVNGEPLDESSYIYTDPTTGEQDLASKDGYEFSVTVPKGRLWVMGDHRGSSGDSRENYIRGGEDVQRATIPVDSVVGKAFLLMWPVAHWKWLSVPDTYSGIPPPKASELSGSCQAGRVRHPRKLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2J1</accession>
    <name>D3Q2J1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019495.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4275"/>
    <dbReference type="EnsemblBacteria" id="ADD43924">
        <property type="protein sequence ID" value="ADD43924"/>
        <property type="gene ID" value="Snas_4275"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4275"/>
    <dbReference type="eggNOG" id="COG4226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105073_1_0_11"/>
    <dbReference type="OMA" id="AMDLTPY"/>
    <dbReference type="OrthoDB" id="1988756at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="17252" checksum="C77D4917F4402BD4" modified="2010-04-20" version="1">MDLSPYLESLRRDLAAAAAPAGDAAVQTAELLAGSLESSLRLALLEALSDAAAEITGELNRTGNPATVEVRMRARQADLVVSETPQAPPEPPPAPSADSGDVARITLRLPEALKVSVENSASAESISVNAWLVRAINAAVHGAPPPPSSSAPAGRARFGRRVTGYAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2J4</accession>
    <name>D3Q2J4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019498.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4278"/>
    <dbReference type="EnsemblBacteria" id="ADD43927">
        <property type="protein sequence ID" value="ADD43927"/>
        <property type="gene ID" value="Snas_4278"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4278"/>
    <dbReference type="eggNOG" id="COG2339">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056942_0_0_11"/>
    <dbReference type="OMA" id="LIRDDEW"/>
    <dbReference type="OrthoDB" id="1626415at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026898">
        <property type="entry name" value="PrsW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36844">
        <property type="entry name" value="PTHR36844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13367">
        <property type="entry name" value="PrsW-protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="404" mass="44212" checksum="7BC5E8EF92D9D0B6" modified="2010-04-20" version="1">MITVERVVVEGQGTFVRVRKPAYWLYVVLVGFGLVSLGSMMSDAVTALSSALWIAALLNGALAAVFVLILSRMDLFEREPAAVRAAAFIWGAVVATSVAIIANNNLLALMTKLFGTGFAARWGAALAGPTNEEWLKTLGVIILVLIVKEHFNRSIDGLTYGAMCGLGFQVTENMVYAINNAYSNPNSDVAGAVSVTVIRILVAGPWSHPIYSGVAGLGIAYAVTTKGMRSPLRRYGIAVGLFIAAWLMHALWNSPLPDGMPNGVGALAVYGKGALILIFFFVLYRYAARYEWHWFERIMTGQSAEVITETEMASMRTLRTRRKARKQADFEYGPKGRKLVARMQRAHLMLGEALARAKRAEVDPNNALDVVVARQNVLAVRAELDAARRLGRKPRKRKRDPART</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2R9</accession>
    <name>D3Q2R9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6197</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021391.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45820">
        <property type="protein sequence ID" value="ADD45820"/>
        <property type="gene ID" value="Snas_6197"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6197"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="VIYPYWH"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="2">
        <location>
            <begin position="16"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="339" mass="37042" checksum="8087F4C626781DE5" modified="2010-04-20" version="1">MQYRNLGRTGVQVSSLALGAMNFGAIGRTTQDDAIAIVDAALEGGINLIDTADMYSQGESEKLVGTAIAGRRDDIVLATKASMPMGQERNHQGASRRWLVTELDNSLRRLGVDHVDLYQIHRWDPDTSDEETLSALTDLQRAGKIRYFGSSTFPAYRIVEAQWAAREHRLSRYVTEQPSYSILQRGIEAHVLPVTERYGLGVLAWSPLASGWLSGAIREGREFTTNRATMMPERFDTALPANRARLDAVEQLVKIAEEADLTLIQLALGFVTAHPGVTSAIVGPRTVDHLRSQLAAADTVLSADVLDAIDTVVAPGTDLAAHEKHDTPPALLDPALRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2S8</accession>
    <name>D3Q2S8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tagatose-bisphosphate aldolase</fullName>
            <ecNumber evidence="3">4.1.2.40</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6207</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.40" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021400.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6207"/>
    <dbReference type="EnsemblBacteria" id="ADD45829">
        <property type="protein sequence ID" value="ADD45829"/>
        <property type="gene ID" value="Snas_6207"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6207"/>
    <dbReference type="eggNOG" id="COG0191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040088_0_1_11"/>
    <dbReference type="OMA" id="NNMEIVQ"/>
    <dbReference type="OrthoDB" id="827430at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009025">
        <property type="term" value="F:tagatose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="280" mass="28947" checksum="4EBBF8494AD0AE42" modified="2010-04-20" version="1">MALVPTAELMENTRGGVGAFNVITVEHAEAIVDGAGRAERPVILQISENAIKFHHGQIAPIAAATAAVAETSDVPVALHLDHVTDASLWEVAPQHGFGSVMIDASKLPYAENVDETGRAVEYLNSRGLWVESELGQVGGKDGEAPLSAHAPGARTSPDEAAAYVMDTGVDALAVAVGSSHAMTTRDAVLDHDLIAAIKEAVAIPLVLHGSSGVPDAELAKAVRGGMIKINIGTALNIAYTDAVRGHLAANPDNVDPRKYLAAAREAMAAKVSHFLTVLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3E3</accession>
    <name>D3Q3E3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ADP-ribosylation/Crystallin J1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2295"/>
    <dbReference type="EnsemblBacteria" id="ADD41984">
        <property type="protein sequence ID" value="ADD41984"/>
        <property type="gene ID" value="Snas_2295"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2295"/>
    <dbReference type="eggNOG" id="COG1397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033331_1_1_11"/>
    <dbReference type="OMA" id="RNPFREW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005502">
        <property type="entry name" value="Ribosyl_crysJ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036705">
        <property type="entry name" value="Ribosyl_crysJ1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03747">
        <property type="entry name" value="ADP_ribosyl_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101478">
        <property type="entry name" value="SSF101478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="449" mass="48237" checksum="72D6A7104490CE95" modified="2010-04-20" version="1">MMRLSWTQPEDLVPHALVAAELDGRDTTEIRQRWRDGGGAAEPAVSGATPDPAPEHVRTLARELLSEIDKLPDPEVLRTNEPDDIDDILATTSSSDPPKPGPDFDDRVLGAWLGRASGCLLGKPVEKLPLAGIRAIGRATGNWPLRSYFTEVGLDATTAAKYPWNRRSRPTSLVENIDGMPEDDDLNFPLIALDLLERTGFGFSTEDVAQSWLSHLPGGRVFTAERITYRNLLDGYEPDVAGRVRNPFRDWIGAQIRTDVYGWTNPGQPQRAARLAWTDARLSHGRNGVYGAMFAAAASAAAVTAVPVTEVLETGLSVVPPASRYAAAVRRGTQLGLGDLPDDAAIDVLHEEYGHLHWVHVLNNAALLAFALARGDGDFARTITLAVSGGWDTDSVGATAGAITGALTGAKNLPPRWIDPLDDRLATTVPGFAGARFSNLAARTVAIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3I3</accession>
    <name>D3Q3I3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017595.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2338"/>
    <dbReference type="EnsemblBacteria" id="ADD42024">
        <property type="protein sequence ID" value="ADD42024"/>
        <property type="gene ID" value="Snas_2338"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2338"/>
    <dbReference type="eggNOG" id="COG0590">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_146218_1_0_11"/>
    <dbReference type="OMA" id="FRYVQLK"/>
    <dbReference type="OrthoDB" id="1263341at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="114" mass="12833" checksum="09956E0C2B540675" modified="2010-04-20" version="1">MTAPSLDGRRFGSTENTVDGEVGGDTSFEYFENDSEIWGTYSGGEVRRGYLVGTRDGDALDFRYTHLNTKRETSSGHCLTRIVVLDDGRLRLEETWEWESRPGSGFSAVEELRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3L4</accession>
    <name>D3Q3L4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2370"/>
    <dbReference type="EnsemblBacteria" id="ADD42055">
        <property type="protein sequence ID" value="ADD42055"/>
        <property type="gene ID" value="Snas_2370"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2370"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1276972_0_0_11"/>
    <dbReference type="OMA" id="NTTYQAF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="216" mass="23008" checksum="12DD8CC916A11461" modified="2010-04-20" version="1">MNSTIADTTPEYLGGSSLNLHDGANIYPGTDDDPAILGSGHLSLDGSTGYASTSDPLVNVEEGFTLIARARPTSVVSDHDMTVMALRGHNTNLVEIKYSAEAHAWRVVASKTDTADSETVTIDHRIPPLLEPTGQAIGVTYDAISGEMTLWVAGYAQTPKQVTFAGPWSITGFQVGRGIGDDAYFSGAIDEVRVYAGVCSPDLMYDLSGYYELPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3S0</accession>
    <name>D3Q3S0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">6-phosphogluconate dehydrogenase NAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019558.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4340"/>
    <dbReference type="EnsemblBacteria" id="ADD43987">
        <property type="protein sequence ID" value="ADD43987"/>
        <property type="gene ID" value="Snas_4340"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4340"/>
    <dbReference type="eggNOG" id="COG2084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035117_2_1_11"/>
    <dbReference type="OMA" id="GHGKEQY"/>
    <dbReference type="OrthoDB" id="1194694at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_2" evidence="2">
        <location>
            <begin position="6"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="290" mass="30546" checksum="DFAAC038532C784F" modified="2010-04-20" version="1">MTKTPVSVIGLGRMGATIAEIYLREGHPTTVWNRTPAKAEPLLAKGARPAATVAEAVAASPVSVIMLADDTVVRASLESATSELDGRTIVNLTTGRPDEARELGDWLAGHGAEYLDGGVLGVPQTLATPESVIIYSGSTAANQRHGEIVAALGTARYLGADHGLASLNDMAILSGMYGLFSGYFHSVAMVDSEGFKAAEFTKDLLIPWLRSIVDVLPTLADEIDSGDYPVNFSNLDVNVAGIENIMRTSRSQGVTDAPLVPLRDALAAQQEKGHGEASFSRAVEELKSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q402</accession>
    <name>D3Q402_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6267</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021458.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6267"/>
    <dbReference type="EnsemblBacteria" id="ADD45887">
        <property type="protein sequence ID" value="ADD45887"/>
        <property type="gene ID" value="Snas_6267"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6267"/>
    <dbReference type="HOGENOM" id="CLU_2958566_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="59" mass="6640" checksum="ABAE67C3F4BBAF5B" modified="2010-04-20" version="1">MTTTHKTTVEYDGTRRYPWLPTCTCGEQFWGYVAEHAAQAIVDEHVAETSGRPVGREAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q444</accession>
    <name>D3Q444_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATPase AAA-2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_6311</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
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    <dbReference type="EnsemblBacteria" id="ADD45929">
        <property type="protein sequence ID" value="ADD45929"/>
        <property type="gene ID" value="Snas_6311"/>
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        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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            <end position="170"/>
        </location>
    </feature>
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        <location>
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            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="822"/>
            <end position="854"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="ADD45929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="854" mass="94609" checksum="1A2F0A63AED8B6B8" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4G0</accession>
    <name>D3Q4G0_STANL</name>
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        <submittedName>
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        </submittedName>
    </protein>
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    </gene>
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        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ADD40120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ADD40120">
        <property type="protein sequence ID" value="ADD40120"/>
        <property type="gene ID" value="Snas_0403"/>
    </dbReference>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_6_11"/>
    <dbReference type="OMA" id="WTISRPG"/>
    <dbReference type="OrthoDB" id="1616572at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="10"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="287" mass="30266" checksum="CEF436DF9ECD125C" modified="2010-04-20" version="1">MTQQPILVTGATGKSGRRVVSQLRAKGLPVRAASRDGEHHFDWNDTGTWDPALAGTQAVYIVQLDGTRLVRGFVERAVGHGVRRIVLASGRGIDNPDYATDSGGVLDGLLDSEAAVRESGVNWTISRPGWFAQNFSEGFFAEAVRAGELRLPGGDGAASFIDAEDIAAVVTAALTDDRHAGQVYELSGPHAVTLAEAVATIAGVTGRDIRYVPLSVADYVDELVGQGLSSVDAKAFADVIEPLREGVDEYLSDGVQRALGRPPRTFTQFVEATAAAAGGWHTAATRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4J5</accession>
    <name>D3Q4J5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0440</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ADD40155">
        <property type="protein sequence ID" value="ADD40155"/>
        <property type="gene ID" value="Snas_0440"/>
    </dbReference>
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    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013104_0_0_11"/>
    <dbReference type="OMA" id="WIAGGHD"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="589"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="633"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="223"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="396"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="666"/>
            <end position="673"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="868" mass="92539" checksum="04EE2D018A4F3860" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4K9</accession>
    <name>D3Q4K9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0454</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015740.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0454"/>
    <dbReference type="EnsemblBacteria" id="ADD40169">
        <property type="protein sequence ID" value="ADD40169"/>
        <property type="gene ID" value="Snas_0454"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0454"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="VVHMARM"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="316" mass="34037" checksum="9404300D2C3AAE7F" modified="2010-04-20" version="1">MSTITIEALTKRYSRVTALDQLTVDVPEGVCGLVGANGAGKSTLIKILLGLSTPTAGRASVLGYDIASHGPEIRQLVGYMPEHDCLPPDVSAAEFVMHMARISGLPTGAARERTADTLRHVGLMEERYRRMGGYSTGMKQRVKLAQALVHDPKLVFLDEPTNGLDPVGRDEMLDLIRRIHTKFGISVLVTSHLLGELERTSDHVIIIDGGRLLKSRSTGELTSQTHTLILEVLDPAGGADAADRAQASLEASGLGVRRAGELMYVPATDESTFDSIRDTVAHAGLGLVRLQRDRHHIAEIFAENTPEGSQDHVVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4M9</accession>
    <name>D3Q4M9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PRC-barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015760.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0474"/>
    <dbReference type="EnsemblBacteria" id="ADD40189">
        <property type="protein sequence ID" value="ADD40189"/>
        <property type="gene ID" value="Snas_0474"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0474"/>
    <dbReference type="eggNOG" id="COG1873">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1821262_0_0_11"/>
    <dbReference type="OMA" id="HIDQERS"/>
    <dbReference type="OrthoDB" id="1849143at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030077">
        <property type="term" value="C:plasma membrane light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045156">
        <property type="term" value="F:electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019684">
        <property type="term" value="P:photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014747">
        <property type="entry name" value="Bac_photo_RC_H_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRC" evidence="1">
        <location>
            <begin position="24"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="142" mass="16162" checksum="81503FD29DBAFA9C" modified="2010-04-20" version="1">MANETATLVRLRDTGLTLAHEEEDVRGMTVVDRNGDEIGHVEDLFIDETQRRLRFLEIGSGGFLGIGKEKRLIPVDAITRVDEQVHIDQERSHVAASPGYDPELTPMPEPPTIEEIYGHYGYIPFWGPGYMYPIFPSRRPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4T3</accession>
    <name>D3Q4T3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome oxidase assembly</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2430</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2430"/>
    <dbReference type="EnsemblBacteria" id="ADD42113">
        <property type="protein sequence ID" value="ADD42113"/>
        <property type="gene ID" value="Snas_2430"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2430"/>
    <dbReference type="eggNOG" id="COG1612">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060266_1_0_11"/>
    <dbReference type="OMA" id="LVYAWLM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016653">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003780">
        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="325" mass="34150" checksum="5DC836E4A1B34610" modified="2010-04-20" version="1">MCQQPGIRALPVIFYNVSPKWVRRLSLANIIVNVAIVVTGGAVRLTGSGLGCPSWPNCAPGTFHATPEMGMHGAIEWGNRLFGAIVALVAIVTFVAALLRKPKRASLVWLTGFIGVAVAVQAFIGAATVGTDLSPWMVSVHFLVSIAILAAALVAWVRAGEPDGEVRLTVPKPVRSLWWVLVGVTVAVLFVGTLVTGAGPHAGDKDSPRSGLDTELISQAHADLVFLLVGVTIGLVFTLRVAGAPAAASRRVWVLIGVIAAQGLIGFVQYFTDLPAPLVGAHLLGAAVLWLTVLWVGVPMRERLAPSLEVRQRPAAERVTAEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4U2</accession>
    <name>D3Q4U2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formyl transferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017693.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2439"/>
    <dbReference type="EnsemblBacteria" id="ADD42122">
        <property type="protein sequence ID" value="ADD42122"/>
        <property type="gene ID" value="Snas_2439"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2439"/>
    <dbReference type="eggNOG" id="COG0223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073809_1_0_11"/>
    <dbReference type="OrthoDB" id="2009156at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016742">
        <property type="term" value="F:hydroxymethyl-, formyl- and related transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="1">
        <location>
            <begin position="97"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="252" mass="28966" checksum="917321E66972E743" modified="2010-04-20" version="1">MSRLRVAILRADDHHHRYLEWTLRSAFDVVFVAVEPGGEKVRRMWTNRRYRNYFYNRYHDLRRRWSGKDRYRREYFRHGPALPSTVETVPAVNSEPVVTGLRRAAADVTVVIGCSILKNDVLAAAGAPIVNLHGGFLPDYKGNHCVFFALYNGEPDKVGVTIHHVNAGVDAGDLIEVVRPPVHGGETAEHLYCRSEKIAINRLVRHLRRLEAGHALPAHPQPKRGRNYLTRDRGPSHDLRMWWRSRFKAART</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4V2</accession>
    <name>D3Q4V2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycerophosphoryl diester phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017703.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2449"/>
    <dbReference type="EnsemblBacteria" id="ADD42132">
        <property type="protein sequence ID" value="ADD42132"/>
        <property type="gene ID" value="Snas_2449"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2449"/>
    <dbReference type="eggNOG" id="COG0584">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074029_0_0_11"/>
    <dbReference type="OMA" id="YIGYGWT"/>
    <dbReference type="OrthoDB" id="1542724at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="71"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="334" mass="37088" checksum="C4B6F0BC21390068" modified="2010-04-20" version="1">MSEDSLPASKTTKPRFRKLKITGIALLLLAGFVFVNNTSLLAFPGGDAPQLLAHRGMSQTFDMSGVDSDTCTAERINEPRHDYLENTIRSMKAAFDAGADQVELDVQMTKDDQFAVFHDWELDCRTEASGKTRDLTMAQLRKLDIGYGYTADGGKTFPFRGKGVGMMPSLDEVFDEFGSQELLLHIKSDDPAEGELLAKRLSTLSDKRLRAITVYGGDKPIAALREKMPKLRVMSKALMMECLGWYEGLSWIGTVPASCRNTQLHIPESYAPWLWGWPHRFGERMASVGTRVVLVAGSGEHSEGFDSAESLRRIPEDFTGMVWTNSIEVVAPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4W1</accession>
    <name>D3Q4W1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YceI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017712.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2458"/>
    <dbReference type="EnsemblBacteria" id="ADD42141">
        <property type="protein sequence ID" value="ADD42141"/>
        <property type="gene ID" value="Snas_2458"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2458"/>
    <dbReference type="eggNOG" id="COG2353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071003_3_0_11"/>
    <dbReference type="OMA" id="FKCMQHP"/>
    <dbReference type="OrthoDB" id="1767227at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YceI" evidence="1">
        <location>
            <begin position="13"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="187" mass="20488" checksum="23C8062863C2FF28" modified="2010-04-20" version="1">MNTTAIDPTLSGTYVVDPTHSRFGFVARHAMVTKVRGSFPEFEATGFLNTDDPTSSTAEVTLQVASVDTGNEQRDGHLRTNDFFDAPNHPQITFRSTSVEDRGDNEYRLNGDLTIKGVTKPISVDLEYTGTALDPYGNRRIGLEGTATLNRRDFGVNFQAALETGGVLVSDKINLEFDISAIQQKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q582</accession>
    <name>D3Q582_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4486</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019702.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4486"/>
    <dbReference type="EnsemblBacteria" id="ADD44131">
        <property type="protein sequence ID" value="ADD44131"/>
        <property type="gene ID" value="Snas_4486"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4486"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136818_0_0_11"/>
    <dbReference type="OMA" id="AWFEGRY"/>
    <dbReference type="OrthoDB" id="1846332at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="39"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="169" mass="18771" checksum="03E33C84F5A5CB81" modified="2010-04-20" version="1">MYSPDRQANHCAFCGTRFQPTTTWPRDCPSCHETTWANPLPVAVTLLPTTDTDGTTNLVIVRRTIEPGSGLLALPGGYIELGETWQQAAVRELREESHIEADPNDVQLFHVDNSVRTIQIFALLPTRPVTDLPPSTPTPEADGWHLLPAPTELAFPTHTTAARMFFENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5B1</accession>
    <name>D3Q5B1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isochorismate synthase</fullName>
            <ecNumber evidence="3">5.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4515</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate = isochorismate</text>
            <dbReference type="Rhea" id="RHEA:18985"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="EC" id="5.4.4.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the isochorismate synthase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.4.2" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4515"/>
    <dbReference type="EnsemblBacteria" id="ADD44160">
        <property type="protein sequence ID" value="ADD44160"/>
        <property type="gene ID" value="Snas_4515"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4515"/>
    <dbReference type="eggNOG" id="COG1169">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006493_8_6_11"/>
    <dbReference type="OMA" id="TMWHLSS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008909">
        <property type="term" value="F:isochorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004561">
        <property type="entry name" value="IsoChor_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00543">
        <property type="entry name" value="isochor_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate_bind" evidence="5">
        <location>
            <begin position="123"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="401" mass="42288" checksum="42B1EBEA00F15193" modified="2010-04-20" version="1">MSTVAPRFADTPLSPLWSVHMHLVDEYRPGSSFFFDTGSRSLLTHGSAIVLPGRGGLAPARADTVLRALGGDQLLVGAVPFSDTEPAQLLVPDVYRWGPGLAGAEAAPTHSHDTPALCEPPPQHYRDAVATALADIDATELSKVVLARSLRIGLDAPVDIPAVLRQLRHRQRRGYVFACPLPEQRDLVGGSPELLVSRNGDVVTAHPLAGSRPRSGDPRVDTARGAELLASEKDRREHAVVVDAIARSLDPYCAELSAPSTPEIVSTGHMLHLGTRVTGRLRDPLPSALSLAAALHPTPAVCGTPTATAREAIARLEGFDRGFYSGMVGWCDSAGNGEWAVTIRCAEIGARDVRLFAGAGIVAGSDPAAELAETEAKLQTMLSALGHTGKVVDERAVHAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5H2</accession>
    <name>D3Q5H2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_6416</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021603.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6416"/>
    <dbReference type="EnsemblBacteria" id="ADD46032">
        <property type="protein sequence ID" value="ADD46032"/>
        <property type="gene ID" value="Snas_6416"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6416"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_2_11"/>
    <dbReference type="OMA" id="CFITNSG"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="122"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="232"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD46032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="384" mass="41668" checksum="A843A9D2C5D93A65" modified="2010-04-20" version="1">MDFRLSTEETALREAVEEFAREKVAPVAGDLYERGEFPYKLVAQLGEMGIFGACFDDKYGGAGGDYFMLCLALEELGRVDSSLAITVEAAVSLGAMPIYRFGTDEQKQRWLPKLCRGEALAAFGLTEPDGGSDAGATKTRAVLDGDEWVINGGKCFITNAGTDITEFVTVTAVTGTKPDGHKEISTIIVPRDTPGFTVGPKYSKVGWSSSDTRELFFDDCRVPAANLLGERGRGYAQFLRILDEGRIAIAALATGLAQGCVDESIRYAKERHAFGHPIGDFQAIQFAIADMELRAHTARLGYYDAAARMRADAPFKRQASIAKLHASNAAVDNSRAATQIFGGYGFMNETPVARMWRDSKILEIGEGTSEIQRMLIARDLGVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5K0</accession>
    <name>D3Q5K0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6444</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6444"/>
    <dbReference type="EnsemblBacteria" id="ADD46060">
        <property type="protein sequence ID" value="ADD46060"/>
        <property type="gene ID" value="Snas_6444"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6444"/>
    <dbReference type="eggNOG" id="ENOG5032TTP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_674238_0_0_11"/>
    <dbReference type="OMA" id="DSYAECV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD46060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="408" mass="40141" checksum="B1F68314A542C335" modified="2010-04-20" version="1">MLAPVEGETVTIKLKGLGQVAVAVGVIGVVSSMLLVPMSAAAETRSASSALAELDVTAIPAVGVDAFSGSYGTAGTPDLSKSADSVDGDFSDPDGVLDHMAVNGTQVSATSWESTTGQLTARTNATGFEVNYNGVDDFMTSGSIDSYARCLNNGGALAYARGDGSLAYVLGKPVSAGANTIEATGAQLNMSAVDTATLTVTVKRVENAVNTPTEVSAEAFFEIIVEGQLRDSAGDVIYDGPMLTLIEGHVKVTCKPQQEPTPSSSSATSSSSSSSATSSSSSSNSSSSSSSSSSSSPSTSSSSSSTSTSESPSSTSESPSPSSSSASPSSTTGSPSTSGSPSSSGSTSASSSASDDTTEPVAPTTAAADDGRGTLSVTGNSVLGVLVAGLSAVALGAFLLIVAKRRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5K8</accession>
    <name>D3Q5K8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_6453</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021639.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6453"/>
    <dbReference type="EnsemblBacteria" id="ADD46068">
        <property type="protein sequence ID" value="ADD46068"/>
        <property type="gene ID" value="Snas_6453"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6453"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_19_4_11"/>
    <dbReference type="OMA" id="SFVAMYT"/>
    <dbReference type="OrthoDB" id="1118058at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="29"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD46068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="410" mass="42159" checksum="6CDEF733701CB3F5" modified="2010-04-20" version="1">MASTTTLPSAAMTPATARAETRHAPLARTIPVFVLTALLATGQMYTAIPLFNAMEASWQVPASAMTWIVSAFAFGYAGGFILFGPLSDRFGHRRVIVTGMAAAGVVTLLTGLAFSMPLAVGLRVLQGLAIGSIPPAIMAYIGTRFAPRQRHVVITSVATSFLASTVLAQVASQLVVASFDWRVVFIGSAVLFGLLALALRWVMLDDAPATGISVRHSYAAIPAVLRTRAIWPVLGAGSLAMGVMVAVYTGIELTGLVHGNGELLGLRASALPIMFALPLLAAPLGRLARRSQIMLGIGLAAAAMVATAVVGSHVVPVAILLAFLVGGLGIVGPASLQTAGDLGGDHRAAASSVAMFIFYVGATVGPMVAAVVAPHGFAALAWTLAAMLALAFALLAPGARRRGHHPPPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5Q2</accession>
    <name>D3Q5Q2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015772.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0486"/>
    <dbReference type="EnsemblBacteria" id="ADD40201">
        <property type="protein sequence ID" value="ADD40201"/>
        <property type="gene ID" value="Snas_0486"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0486"/>
    <dbReference type="eggNOG" id="ENOG502ZUEP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1585462_0_0_11"/>
    <dbReference type="OrthoDB" id="1808686at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="18080" checksum="A9C4DF0DB8A49C5F" modified="2010-04-20" version="1">MSRKILRILGSRYGIAAILLVVVIIVVGLARANGGTDSDTTVDGSDSMGTEDAGEPNDGVVTESDEESAESSLPKKAVDNATEFAKAYIKTDRSAKAWRADVGKNATQKVKDELKYIDPEVVPIKEITDDPSAEGQTVRFPTDAGLLILRMKVQDEVWLVDGIDLDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5Q7</accession>
    <name>D3Q5Q7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0491"/>
    <dbReference type="EnsemblBacteria" id="ADD40206">
        <property type="protein sequence ID" value="ADD40206"/>
        <property type="gene ID" value="Snas_0491"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0491"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_882522_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="2">
        <location>
            <begin position="17"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="315" mass="33810" checksum="C8E477925F67C8FE" modified="2010-04-20" version="1">MTSRHAVTSQPLHPLLATRYSTRAFDPSGKVTDAQVTALLEAARWAPSSGNTQPSRFIVGRRDSPVFARVLATLRPGNQQWARHAALLLVAVRVTANAKGPLPHAAYDLGQAMAHLVVQAQAEGLTVRQMAGFSPSAVTEEFGLAEELVPTTVAAIGVAGDPAALPDDLRGPDDNPRRRKPLDELILAELQVRVRRFLGVAQPQRPGGAGALRVAAGGVDRRGHELPGDHSRAVVWWTVSIRGHGFHADHVSLGVLAVCYAITVAQLNPHAARPIASAGTDHNTVTVPYRLEISPRGRGQRHRNLNPRNTHVRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q610</accession>
    <name>D3Q610_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0595"/>
    <dbReference type="EnsemblBacteria" id="ADD40309">
        <property type="protein sequence ID" value="ADD40309"/>
        <property type="gene ID" value="Snas_0595"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0595"/>
    <dbReference type="HOGENOM" id="CLU_908848_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="331" mass="36700" checksum="3F8DD69EE7A8C420" modified="2010-04-20" version="1">MPTEEGSINSNTDRQTSRIKPRWMALSVIGILCLGVCIWWFADSKPESTSSSIEDSFILENASFYLFDQGVPQEKVQLNQGKYSPPGNADNGAHVRVDSKVQFADLDGDQDIDASAILEWVDNSGDKYSSWRALYFWLWDDNKVVPVKWPGAWQWNCVTKDQPKGGALSITSPASPFGVVIERNTNNLCGDDILDKKARTDASYFIGVKKGYPVVTAGQDLALATESCTGGDSDDPASSLKYTNITDTLKSDPRVQPFKNAPVVDGPRPPKKSPSKPTAQAPKIEYMIDKEFEPSDRYLRVHDGFVPVVIVWGYDYQGCGWASWDNVKKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q619</accession>
    <name>D3Q619_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class I and II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017765.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2512"/>
    <dbReference type="EnsemblBacteria" id="ADD42194">
        <property type="protein sequence ID" value="ADD42194"/>
        <property type="gene ID" value="Snas_2512"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2512"/>
    <dbReference type="eggNOG" id="COG0436">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_615248_0_0_11"/>
    <dbReference type="OMA" id="RESWINR"/>
    <dbReference type="OrthoDB" id="426203at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="133"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="445" mass="49445" checksum="01920F64D5144C8B" modified="2010-04-20" version="1">MLTAETLNALLNDEILPSRMPDAGLLTDYLRTSDPRPEPICLSFGETWSQVAPGLAARLATEPVHSHGYQLSQYGLPALRLLVRDQLRREHRLPDDSQAGRDYEVAVGWTGTRSAMFDFGRMILDQDAPSDAEPVVVVAGPSWDYEGVYGSLGYRVRYHHLRPESGFRPDAAELRQLFAEIGAGGEQRPALLVVNAQHNPTAVNWDAEFVTEAVSIAAESGAAILIDDAYYAVHDDDIEPTSALSILLGMLPGLPKSLRRRWLAVRSFGKQFHSNGWGIGALTADPKILDALVNRYRLHHGLMYGGCYQHAMRSWLADEASREFLVQQRRSYRSRRKMIGDYLTSRLGYPADRVHVGECSSYLMFAVPEAYAGLDDPAERFRLDCFAATGVLFAPAWPWPFIADRGPGLPWVRMFIGPSSQTITTALDRLADNGFRYDMAVSATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q636</accession>
    <name>D3Q636_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acyl-D-aspartate deacylase</fullName>
            <ecNumber evidence="2">3.5.1.83</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.83" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017782.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2530"/>
    <dbReference type="EnsemblBacteria" id="ADD42211">
        <property type="protein sequence ID" value="ADD42211"/>
        <property type="gene ID" value="Snas_2530"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2530"/>
    <dbReference type="eggNOG" id="COG3653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016107_2_1_11"/>
    <dbReference type="OMA" id="HATMNFG"/>
    <dbReference type="OrthoDB" id="1319925at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047422">
        <property type="term" value="F:N-acyl-D-aspartate deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023100">
        <property type="entry name" value="D-aminoacylase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="41"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="522" mass="55726" checksum="8BEC621F42A0D452" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q650</accession>
    <name>D3Q650_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017796.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2544"/>
    <dbReference type="EnsemblBacteria" id="ADD42225">
        <property type="protein sequence ID" value="ADD42225"/>
        <property type="gene ID" value="Snas_2544"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2544"/>
    <dbReference type="eggNOG" id="COG1975">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041115_1_0_11"/>
    <dbReference type="OMA" id="HTPIHHD"/>
    <dbReference type="OrthoDB" id="1879870at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003777">
        <property type="entry name" value="XdhC_CoxI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027051">
        <property type="entry name" value="XdhC_Rossmann_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13478">
        <property type="entry name" value="XdhC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02625">
        <property type="entry name" value="XdhC_CoxI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XdhC_CoxI" evidence="1">
        <location>
            <begin position="11"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="XdhC_C" evidence="2">
        <location>
            <begin position="213"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="385" mass="39987" checksum="33EF84F4675ADEFC" modified="2010-04-20" version="1">MRDIAAELADWLRTGRHFAMASVIDVAGSAPRPIGTALAVDADGTAVGGVSGGCVEGAVYELCQQVLATGESRIESFGYSDEDAFAIGLTCGGTVTVFVTRVEPGDPALLATVDAILAGRSVAVARAISGPGAGRALAVTDQAATPERPDCQAASGSLGDATADTVIGSLGAADVDAAAAEQARELLARGGFGRFDTGIGEVLVETYPSPPRLLVFGAVDFAAAVVRAGKFLGYRVTVCDARPIFATELRFPEADEVVVDWPHRYLDATTIDERTAVCVLTHDPKFDIPLLERALRLPLGYVGAMGSRRTHRDRVRRLREKGVTDTELAALHSPIGLDLGGRTPEETALSIAAEIVALRNNADGGFLSATDVPIHRGRGGAVEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q666</accession>
    <name>D3Q666_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017812.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2561"/>
    <dbReference type="EnsemblBacteria" id="ADD42241">
        <property type="protein sequence ID" value="ADD42241"/>
        <property type="gene ID" value="Snas_2561"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2561"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_11"/>
    <dbReference type="OMA" id="DHIDVYR"/>
    <dbReference type="OrthoDB" id="1054546at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="16"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="332" mass="35239" checksum="6E23C06AFDD8D371" modified="2010-04-20" version="1">MKQRQLGSTGPTVATLGLGLMGMSDMYGPADETESIATVHAALDAGINLLDTGDFYGSGHNELLLSRALKGRDRDQVVISVKTGALRDPAGGFVGVDTRPATLKNALAQTLRKLDTDHVDIYRPARLDPAVPIEDTVGAIAELVKEGYVRHIGLSEMGSDTLRRAAAVHPIVDLQIEYSLISRGIETGVLPTARELGIGITAYGVLSRGLISGHWTKSREKGARDFRAHSPRFSGDNLDRNLALVDALRAVAEAKGATPAQAAIAWVASRGEDIVPVIGARRRERLSESLGALDLELDAADLAAIEAAVPVETVAGERYDAHQMALLDSEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q671</accession>
    <name>D3Q671_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2566</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017817.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2566"/>
    <dbReference type="EnsemblBacteria" id="ADD42246">
        <property type="protein sequence ID" value="ADD42246"/>
        <property type="gene ID" value="Snas_2566"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2566"/>
    <dbReference type="eggNOG" id="COG1510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078983_0_0_11"/>
    <dbReference type="OMA" id="FAWISEQ"/>
    <dbReference type="OrthoDB" id="1265289at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_38" evidence="3">
        <location>
            <begin position="4"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="103"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="237" mass="26217" checksum="55058314910EFC93" modified="2010-04-20" version="1">MPGERLTQQDRRHIAAGLRDGLTYAAIARRIGRPTSTVTREVTRNGGPRHYYADRAHRASKHPEPRHRPTPRPARGGVDLGGRDPRTVEQTAAQLTDLFVQTGLSQMVAKVLAALLTTDGGSLTSAELVRRLGVSPASISKAVGYLEGLEMIKRERDPRNRAERYVFDDDAWFRTVMANSRVDALIVTVSARGAQSLGAETPAGSRLDRLSQFLNHVNEDVARSAERWRHVLFPPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6G2</accession>
    <name>D3Q6G2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcriptional repressor NrdR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nrdR</name>
        <name evidence="10" type="ordered locus">Snas_4561</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NrdR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019776.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4561"/>
    <dbReference type="EnsemblBacteria" id="ADD44205">
        <property type="protein sequence ID" value="ADD44205"/>
        <property type="gene ID" value="Snas_4561"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4561"/>
    <dbReference type="eggNOG" id="COG1327">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108412_1_0_11"/>
    <dbReference type="OMA" id="YRFTTYE"/>
    <dbReference type="OrthoDB" id="1551627at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00440">
        <property type="entry name" value="NrdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003796">
        <property type="entry name" value="RNR_NrdR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30455">
        <property type="entry name" value="PTHR30455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00244">
        <property type="entry name" value="TIGR00244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0678">Repressor</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ATP-cone" evidence="9">
        <location>
            <begin position="46"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="zinc finger region" evidence="7">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD44205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="156" mass="17391" checksum="AC3DB329DE9B1E6F" modified="2010-04-20" version="1">MRCPYCKHPDSRVVDSREAEDGLLIRRRRSCQECGKRFTTVEESILAVVKRSGVTEPFSRTKVASGVRKACQGRPVDDDALAVLAKRVEDEIRAKGMAEIPSNEVGLAILGPLRELDEVAYLRFASVYRSFESVEDFAAEIEALRDNRETGAEATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6P8</accession>
    <name>D3Q6P8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019862.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4648"/>
    <dbReference type="EnsemblBacteria" id="ADD44291">
        <property type="protein sequence ID" value="ADD44291"/>
        <property type="gene ID" value="Snas_4648"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4648"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027068_0_0_11"/>
    <dbReference type="OMA" id="KPWCAGI"/>
    <dbReference type="OrthoDB" id="480174at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049592" evidence="1">
        <location>
            <begin position="29"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="448" mass="49689" checksum="63C05DB85CB32E99" modified="2010-04-20" version="1">MIAPRKQRRLTAIAASTLTLALAVSACGAPEEDSNLSDKEKDCASYEKYGDFKDKDAEVSIYTPITDAEGDAYEKSWAYFAECTGIDVKYTGSNDFEAQIEVKVKGGKAPDIAFFPQPGLMARYKDKMVPASKKLVKEAEKGWSEDWLQYGTFDDELYAQPMSASLKSLVWYSPKYFKDNDLEVPETWDDLLAVSDKIAKTDVKPWCAGIESGEATGWPVTDWVEDALLRESGGELYDKWVNHEIAFNDKRIVKALDKVGGILKNKDYVNGGYGDVDSMAKVSFEEGGQPIVKGECAMHRQASFYAAQWPEGTKVGPDGDVFAFFLPGNKAEEKPLLGAGEFVAAFRDDPEVHAVREFLASELYVNARLKTGPLAFSHKGADPKNADNELNKMVIELYQDEGAEFRFDGSDQMPGHVGSKSFFVEMTKWIKGKSSKDALDAIEKSWDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Q8</accession>
    <name>D3Q7Q8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019971.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4758"/>
    <dbReference type="EnsemblBacteria" id="ADD44400">
        <property type="protein sequence ID" value="ADD44400"/>
        <property type="gene ID" value="Snas_4758"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4758"/>
    <dbReference type="eggNOG" id="COG3173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079051_0_0_11"/>
    <dbReference type="OMA" id="CEYPSLL"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="2">
        <location>
            <begin position="49"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="336" mass="36220" checksum="9D561D704FD43F7D" modified="2010-04-20" version="1">MGVEVQRERPPRAALAWAERVLGGEVTRVRAFTGGMTSAVHQLSLRLADGRTRQAVLRRYVLSEVLDDVPDIVEREDVVLRLLDDVELPTPRLLGSDGLKRRAADGGPDVPALLMERLPGRPVWRPHEENWLRGLAEVLPVLHAVRAGGEAGAAGSSPGVDGARAGSAAAGSALPSPDGGGSPAGAWADGVAAFEAYEPERYEPPPWLRRPKLWERALELFQRPVGEPSVLIHRDYHPGNVLWRGGKVSGVVDWQSACAGPPSIDVGWCRLELLQECGFEPAMQFTALWEDLAGATYHPAAEVTLLVDKLGMTHDEPPPLPQVHEELLAKALAALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q800</accession>
    <name>D3Q800_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin--[biotin carboxyl-carrier protein] ligase</fullName>
            <ecNumber evidence="2">6.3.4.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0793</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.3.4.15" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016076.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0793"/>
    <dbReference type="EnsemblBacteria" id="ADD40505">
        <property type="protein sequence ID" value="ADD40505"/>
        <property type="gene ID" value="Snas_0793"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0793"/>
    <dbReference type="eggNOG" id="COG0340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051096_5_0_11"/>
    <dbReference type="OMA" id="AVWKHIE"/>
    <dbReference type="OrthoDB" id="1842956at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin-[acetyl-CoA-carboxylase] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003142">
        <property type="entry name" value="BPL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02237">
        <property type="entry name" value="BPL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="3">
        <location>
            <begin position="5"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="263" mass="27804" checksum="B09CC3D9AD6D4874" modified="2010-04-20" version="1">MERKPLDAARLRRWCRDSRMWDSIEVLETVDSTNSLLAKRAAQGAHAGSVLVAEKQTAGRGRLSRSWESPPHAGLAVSMLLRPEVPTARWSWLPLLAGVATCQTIVDLCGVPAALKWPNDVLVGARLDKCSGILAEIAAGGVVLGIGLNVTLAREELPRADTTSLALAGAVETDRGTLLEGLLERIAAWYANWRATEGDPQASGLADAYTLRCHTLGLNVTVSLPDGAVITGVASAIDADGRLCVETEDGPVAVAAGDVYHVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q873</accession>
    <name>D3Q873_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018018.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2771"/>
    <dbReference type="CAZy" id="GH73">
        <property type="family name" value="Glycoside Hydrolase Family 73"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42447">
        <property type="protein sequence ID" value="ADD42447"/>
        <property type="gene ID" value="Snas_2771"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2771"/>
    <dbReference type="eggNOG" id="COG1705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_905875_0_0_11"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002901">
        <property type="entry name" value="MGlyc_endo_b_GlcNAc-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01832">
        <property type="entry name" value="Glucosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00047">
        <property type="entry name" value="LYZ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYZ2" evidence="2">
        <location>
            <begin position="147"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="307" mass="32831" checksum="C713B62EC3FCE980" modified="2010-04-20" version="1">MHIDVSQVQNTGQRIGRVGADAESYLRTMSGPLQQSTQANTGFSAVQRLRQVLDTLAKQTGELITGTNTTAGNVGKAAQAHARAEQRNQRSMRDLNQQLAAKNIKGPKGSGGSTPSKVPTPTPNPLREVLGPGGKPAEASPTQIAPASGKPGSRQEFINNVGNAAKAGQERFGVPASVASAQAILESGWGKSGLAQEANNYFGIKCADGDPGSTASSCVNYKTWEVINGNDTTVRDAFRAYDSPSDSFLDHGQFLSENPRYAEAFKHTDDPDQFIREVHKAGYATDPGYADKIIGLMQKYDLYRFNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8J8</accession>
    <name>D3Q8J8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4799</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4799"/>
    <dbReference type="EnsemblBacteria" id="ADD44440">
        <property type="protein sequence ID" value="ADD44440"/>
        <property type="gene ID" value="Snas_4799"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4799"/>
    <dbReference type="eggNOG" id="ENOG5032T12">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1427322_0_0_11"/>
    <dbReference type="OMA" id="SERMNAS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="217" mass="24916" checksum="0E4CD458A7214311" modified="2010-04-20" version="1">MTILTHLGPVLTRAELSTRGWTRSMVIELLDPPDQRKPNPFYRSSTPMYLYRLERVEQAEAGAEFARLSRRARLRSAQAKATAQRRRDALLAEVRSASITLPSLTRAELAEAAVRHRNKREEQRCYLVPDRHFEPATVDDIDPVTLARWQVDYLRRRQTGYDQLMSAVTGRVGRADATRAIRAKLYNAIATAYPSLRRECDRQLRLPDIPDHASRAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q941</accession>
    <name>D3Q941_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Proton-translocating NADH-quinone oxidoreductase, chain L</fullName>
            <ecNumber evidence="9">1.6.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_0939</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016221.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0939"/>
    <dbReference type="EnsemblBacteria" id="ADD40650">
        <property type="protein sequence ID" value="ADD40650"/>
        <property type="gene ID" value="Snas_0939"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0939"/>
    <dbReference type="eggNOG" id="COG1009">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007100_6_3_11"/>
    <dbReference type="OMA" id="MGICSYF"/>
    <dbReference type="OrthoDB" id="1274678at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018393">
        <property type="entry name" value="NADHpl_OxRdtase_5_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003945">
        <property type="entry name" value="NU5C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42829">
        <property type="entry name" value="PTHR42829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01974">
        <property type="entry name" value="NDH_I_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="581"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_N" evidence="8">
        <location>
            <begin position="62"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="7">
        <location>
            <begin position="127"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="604" mass="62443" checksum="BDBAD725E942EA8F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q972</accession>
    <name>D3Q972_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016252.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0971"/>
    <dbReference type="EnsemblBacteria" id="ADD40681">
        <property type="protein sequence ID" value="ADD40681"/>
        <property type="gene ID" value="Snas_0971"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0971"/>
    <dbReference type="eggNOG" id="ENOG502ZANI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_962356_0_0_11"/>
    <dbReference type="OMA" id="TRYPQPI"/>
    <dbReference type="OrthoDB" id="1715458at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="283" mass="29519" checksum="657F136DE8C7F1FA" modified="2010-04-20" version="1">MTMTTVKSAYPASIADLMPKARKMAEAEGLPSQNRFKETLRIGRPKARELRAALEGEGFQPQRPEPAVLDPDPAPVVPDPVAGTQHDTIELPVVVVADEDIATPEPQDIPVADPGAPTVEVTEPVAVHNSGDTGNADTVERKPIAVWPVLLLLLPATVAIWSGWVGLGKLAGFGPVSPLPGIVDSFVIDTSITLPIGMETYSAYALYVWLSGRASIKAIKFARTSALIALATGAAGQIAYHLMTAANVPAAHPFITAAVACIPVAVLGLGAALAHLVKNTQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9F6</accession>
    <name>D3Q9F6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_2963</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018209.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2963"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42638">
        <property type="protein sequence ID" value="ADD42638"/>
        <property type="gene ID" value="Snas_2963"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2963"/>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1287">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_356349_0_0_11"/>
    <dbReference type="OMA" id="YGMEMLP"/>
    <dbReference type="OrthoDB" id="544842at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="475"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="538"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="565"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="604"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="639"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="9">
        <location>
            <begin position="24"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="10">
        <location>
            <begin position="348"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD42638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="787" mass="87522" checksum="6D66928B71AA2D3F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9M3</accession>
    <name>D3Q9M3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase</fullName>
            <ecNumber evidence="5">4.1.1.112</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Oxaloacetate decarboxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Regulator of ribonuclease activity homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">RraA-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_4928</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + oxaloacetate = CO2 + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:15641"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="EC" id="4.1.1.112"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class II aldolase/RraA-like family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.112" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4928"/>
    <dbReference type="EnsemblBacteria" id="ADD44569">
        <property type="protein sequence ID" value="ADD44569"/>
        <property type="gene ID" value="Snas_4928"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4928"/>
    <dbReference type="eggNOG" id="COG0684">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072626_3_2_11"/>
    <dbReference type="OMA" id="MKLCGPA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16841">
        <property type="entry name" value="RraA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005493">
        <property type="entry name" value="RraA/RraA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03737">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="SSF89562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD44569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="219" mass="23073" checksum="CE7EE484C1901868" modified="2010-04-20" version="1">MSVRDHPGLGNLSAVTTGFENVPTTALADVLGRAQVMDTGIRPLWQPVPSVAGPAFTVRCPPGDNLMLHAAIYRAEPGAVIVVESGDLDYALAGGNVCAVAQRRGVAAFVVDGLIRDLAEVRDNGFPVFARGVIPIPGTKKAVAPLNGEVRCGGVTVNGGDIVVADEEGVVVTPFARRDEVVAAAREKLAKEEAQTLDDWEAEHRARIDKILTDNNFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Q4</accession>
    <name>D3Q9Q4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphonate ABC transporter, periplasmic phosphonate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4961</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphate/phosphite/phosphonate binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020171.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4961"/>
    <dbReference type="EnsemblBacteria" id="ADD44600">
        <property type="protein sequence ID" value="ADD44600"/>
        <property type="gene ID" value="Snas_4961"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4961"/>
    <dbReference type="eggNOG" id="COG3221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051472_6_4_11"/>
    <dbReference type="OMA" id="QGMRFDK"/>
    <dbReference type="OrthoDB" id="988224at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005770">
        <property type="entry name" value="PhnD"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01098">
        <property type="entry name" value="3A0109s03R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049672" evidence="3">
        <location>
            <begin position="28"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="314" mass="34022" checksum="613E39E0C8FFB2CD" modified="2010-04-20" version="1">MRKGLLLRLSALGAIAVLGLSACGESAVGDKDGKGETPDELVISGVPAEEGTDLSNTYEPVVKMLEKELDMKVKFKPSTSYAAVIEGQRNGKIHIAQYGALAYYQALQNGSDIDVLGAMVKAKGAEPGYQAYGIVPKGSKIKDIKDFAGKKLCFVDESSTSGYLYPVAGLMKAGVKKDDWEPVMAGGHDASAIAVSKKECEAGFALDSMVDETLIEKGDIKKGDLKVVWKSDTIAEPPITVYNGLEKGLKDKIKKVFETKANQDYLVKEGFCEKGKCDLTDQRIFGWEPVEESYYDSLTEVCEETKIDACEKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA91</accession>
    <name>D3QA91_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-methyltransferase family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1093</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016374.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1093"/>
    <dbReference type="EnsemblBacteria" id="ADD40803">
        <property type="protein sequence ID" value="ADD40803"/>
        <property type="gene ID" value="Snas_1093"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1093"/>
    <dbReference type="eggNOG" id="COG4122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067676_5_1_11"/>
    <dbReference type="OMA" id="SVARRYW"/>
    <dbReference type="OrthoDB" id="1948290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="219" mass="24160" checksum="0DDB4D1B768DC2ED" modified="2010-04-20" version="1">MGRNVIPLSPELRDYIVAHGTPPDEILRDLAEETYAALPGAAGMQIGPDQTSFMWLLTKIIGVRNAVEVGTFTGMSSLAVARGMEPGGKLICFDVSEEYTAIAKRYWERAGLADNIELRIGDAREGLKQLPSEPHLDLVFIDADKEGYETYWGELVPRMRPGGVLLMDNTLWSGRVVEENPEEESTRALKRFNDVAAADDRVDVVMLPIGDGVTVARKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA96</accession>
    <name>D3QA96_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CDP-alcohol phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1098</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1098"/>
    <dbReference type="EnsemblBacteria" id="ADD40808">
        <property type="protein sequence ID" value="ADD40808"/>
        <property type="gene ID" value="Snas_1098"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1098"/>
    <dbReference type="eggNOG" id="COG1183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_862312_0_0_11"/>
    <dbReference type="OMA" id="PVLWLRQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="284"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="35224" checksum="A86DABEF7FF28892" modified="2010-04-20" version="1">MRTTPWRRRRMSDSPRPAGRGLGRWRRSGSLARRLVAIRPIHPLRTFRRRRNSGDDVRVLETMEMDLALAPVSPAPVGEALVDTDTDPDAPPAPIALLPGDRTPRRRFFFALANACTVISILLGMSAIMLSLTGEVRIAAAVLLGCIIADALDGPLARKFGVASPFGAQMDSLADMCSFGIATPVVVFQWLSGDMPDWAIGGACGLVAVCAAIRLARFNVSPKDGRYFSGVPTTLAATVLALSILLLSVTHVAMAAGIAVLALTMVLGFPYAKLGQLRRVPPWLWILPMVGLYLNLEVTFLALVCAYLLSGPVLWAVHHRRRSVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAI4</accession>
    <name>D3QAI4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GAF sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018338.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3096"/>
    <dbReference type="EnsemblBacteria" id="ADD42767">
        <property type="protein sequence ID" value="ADD42767"/>
        <property type="gene ID" value="Snas_3096"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3096"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034370_1_0_11"/>
    <dbReference type="OMA" id="VKWMEAS"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="62"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="233"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="490"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="578" mass="62057" checksum="228EF96083BE3384" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAM0</accession>
    <name>D3QAM0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018374.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3132"/>
    <dbReference type="EnsemblBacteria" id="ADD42803">
        <property type="protein sequence ID" value="ADD42803"/>
        <property type="gene ID" value="Snas_3132"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3132"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_1_1_11"/>
    <dbReference type="OMA" id="ISASMRF"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="165" mass="18877" checksum="481957D4C183EAEF" modified="2010-04-20" version="1">MTASRDGLLEELVREMPWYISASMRFQMAVADQLDMPLADVHAIGALVEFEPIGAARLAELMGMTSGAVTRLVDRLERGGYVRRSPDPADRRRVVLRAVPERVAEIGRYYASMGESWQRQLADCSDEQLRFLVEFLRRGRDDTQRETARLRSDGRAHGTRRRREP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAV5</accession>
    <name>D3QAV5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020322.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44751">
        <property type="protein sequence ID" value="ADD44751"/>
        <property type="gene ID" value="Snas_5116"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5116"/>
    <dbReference type="eggNOG" id="ENOG5032Y6Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_847061_0_0_11"/>
    <dbReference type="OMA" id="GEPPSPM"/>
    <dbReference type="OrthoDB" id="1056318at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048379" evidence="1">
        <location>
            <begin position="31"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="328" mass="34328" checksum="A3766E3856399940" modified="2010-04-20" version="1">MSRLRRIAMWAVPGLAVALTTAAFVLPANAEPTVDRDKLTTAQKLKLDNAWVDPSADLQFGTEPLASVRTAAEAAVPGASCQISVDAAVALSIAMTWPETAPSGEPPSPMTLSRYDTQPTLGDPEGRAPGLWFHPGIGMWQMDSAGLGTDYTAGEAMNVEYTAGRAVPGILASYCDSLNGGASEASARRAAWQPWVACWEGACEDTYQRALAGVVTVDGVTNLGGAEPRECEFGGVKVECLFVNAANAQGANWWADPAGGRSPVAAPFYVYRLTEGDAVTEIRYWLAADSGAATDVQAARPFGGNARDSLTWSAGAGLCDMTTDRGTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBB7</accession>
    <name>D3QBB7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1224</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016505.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1224"/>
    <dbReference type="EnsemblBacteria" id="ADD40934">
        <property type="protein sequence ID" value="ADD40934"/>
        <property type="gene ID" value="Snas_1224"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1224"/>
    <dbReference type="eggNOG" id="COG3973">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010312_3_0_11"/>
    <dbReference type="OMA" id="KHDARMA"/>
    <dbReference type="OrthoDB" id="114076at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="645" mass="71127" checksum="930C24FBA0DF74B5" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBB8</accession>
    <name>D3QBB8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016506.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1225"/>
    <dbReference type="EnsemblBacteria" id="ADD40935">
        <property type="protein sequence ID" value="ADD40935"/>
        <property type="gene ID" value="Snas_1225"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1225"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087580_0_0_11"/>
    <dbReference type="OMA" id="SNCSWHL"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="15"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="193" mass="21987" checksum="219263F9C70A0E16" modified="2010-04-20" version="1">MTEATHDKPHFSDPELMRVLAHPARLDLIDHLHTVEDATATECAEVVGLSPSALSYHLRALAKVGLVEAAPGRGDGRERVWRLKARSFSIGADYRAPESAKLAQRTMIDSMRRRGDEKFARWMDKAHDEPKEWYDAAMSSEWALLMTAEELAEFNRRLADLTRPYRVRQRKASGEVPDGARRVAFQLRFFPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBU3</accession>
    <name>D3QBU3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5197"/>
    <dbReference type="EnsemblBacteria" id="ADD44832">
        <property type="protein sequence ID" value="ADD44832"/>
        <property type="gene ID" value="Snas_5197"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5197"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1026396_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="271" mass="30172" checksum="C4BA214AD3DDD333" modified="2010-04-20" version="1">MAEYAPEALKWLAREIIKAIPSAELSGIVGDPAHTYGYHRCRNKLPSSDYSVQTKPDREGDGDAASALDMKFNAEWMKKITRRLLDSAKDQNDPRLNYMREFFGTLDGKKVTGWDTYYGKPVTSDDSHLWHIHMSILRKYCTSKDKMANILSVIKGEDDMDLGDRVKVADWINDRWDDVGDSISVRTALGSSYGHARSAKDGIYDKVIPMLEKLTAAREGGAAALSNEDLKQKLTESLTDSLGDKFEDLDGDDLAEAVEKAVDKALDSLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBY7</accession>
    <name>D3QBY7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_5242</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
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        <property type="protein sequence ID" value="ADD44876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="Snas_5242"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:protein serine/threonine kinase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Prot_kinase_dom"/>
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        <property type="entry name" value="Protein_kinase_ATP_BS"/>
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        <property type="entry name" value="Ser/Thr_kinase_AS"/>
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        <property type="entry name" value="Tachylectin2"/>
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        <property type="entry name" value="Pkinase"/>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="11"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD44876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="581" mass="63034" checksum="89CAB5238A3BBF3D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU49</accession>
    <name>D3PU49_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Proton-translocating NADH-quinone oxidoreductase, chain M</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1286</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Membrane</location>
            <topology evidence="1 3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I subunit 4 family.</text>
    </comment>
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        <property type="protein sequence ID" value="ADD40995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="Snas_1286"/>
    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007100_4_4_11"/>
    <dbReference type="OMA" id="ITRWGNQ"/>
    <dbReference type="OrthoDB" id="535707at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="NADH4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010227">
        <property type="entry name" value="NADH_Q_OxRdtase_chainM/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43507">
        <property type="entry name" value="PTHR43507"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01059">
        <property type="entry name" value="Oxidored_q5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01972">
        <property type="entry name" value="NDH_I_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="168"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
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            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="460"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidored_q5_N" evidence="6">
        <location>
            <begin position="67"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="5">
        <location>
            <begin position="132"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="509" mass="53785" checksum="BD0E52F730DCC243" modified="2010-04-20" version="1">MNSFPYLSAVIVVPLIGALITASVPKGKPKQAKAIALGFSLAVAAITVGAWASYDTGDTGMQLTEHYSWVPAWGLNLSFGMDGIALVMLALTALLTPIVILASWNDAHKRNQPTFFALILALQATMIGTFISTNVLLFYIFFEVMLVPMYFLIGSYGGKRRQYAAVKFFLYSLLGGMVLLAAIIGLWVTTGGVFDFATLTDGKHSIAEGTLQNWLFLGFFIAFAIKAPFFPFHTWLPDAGGAAPAGIAALLVGVMDKIGTFAILRYCLPLFPDASQLFAPLAIALALVGVIYGALVAIGQKDLRRLVAYTSIAHFGFIGVGIFAFTTESASGAVLYMVNHGLATGLLFIVVGMLATRRGSSDIADFGGAGKTLPLLAGTFFIAGLASLALPGTAPFVSEFLILLGTYSANKPVAVIATLGVILAAAYVLWMYQRTMQGTVNVKLDGVPAMKRDLNLREKLVVAPLIVGILALGVYPQPVLDVINPAVEHTLDSVGVTGSADQAATGENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUI8</accession>
    <name>D3PUI8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta_helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018572.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3335"/>
    <dbReference type="EnsemblBacteria" id="ADD43001">
        <property type="protein sequence ID" value="ADD43001"/>
        <property type="gene ID" value="Snas_3335"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3335"/>
    <dbReference type="eggNOG" id="COG3420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_615249_0_0_11"/>
    <dbReference type="OrthoDB" id="1055328at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049467" description="Beta_helix domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Beta_helix" evidence="3">
        <location>
            <begin position="103"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="445" mass="47553" checksum="CDA201A0019CBC2E" modified="2010-04-20" version="1">MNKRIVTALIGVTLALTVAGVTVAASADDAETADRPKYGTDGNGNPETGDCTVSTDEDPQSAVDDAADGDVVCVKPGDHSDSTLNVDNAVTVRANGIVKLRNIVVSGDGATIDGFTVVGDELDDPSTGIKFSGTGHEIVNNLVNGKHIHYAIACDADECASDVLISRNSVTQTNNFGVYLWGGSDITVEWNNIYDLWSDEGNDDVDGMRIWGTGHLIRNNYIHDLNVNKGEGEPHADCIQNYQHSSRTDESYGVTVENNYCVRVSGQCLIMQNEHRPSADVRDYTFRGNVCESFGSQNIELGSVTGGTIENNILCGGVDGHVITFHSTVDGLETTDIKLRNNILATAGGSVFADGSKEALIDDTDNIEVTDPTIADDWEEFEGNPDAPVLAINPDDFTVFRDRSQLAGDIIDEGSQPNSSDFHEDVDGAARVRGATIDIGPFEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUJ3</accession>
    <name>D3PUJ3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018577.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3340"/>
    <dbReference type="EnsemblBacteria" id="ADD43006">
        <property type="protein sequence ID" value="ADD43006"/>
        <property type="gene ID" value="Snas_3340"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3340"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_3_1_11"/>
    <dbReference type="OMA" id="LWHFTMS"/>
    <dbReference type="OrthoDB" id="1920912at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="12"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="20048" checksum="7E61CEA249C1B4B8" modified="2010-04-20" version="1">MIDTTPQTADGKVLWHFSMSLDGFVAGPNHSMSWLSRTTSSRPGLVEEYMSTTGAVLGGRSGWDATPEGVRPYNDWQGPIFILTHHPEDARKEEGVTLLNCDVAEAVRIGLEAAGGKNLEVFSPTIGAQLLERGLIDEIDLHISPVLLGDGVRLFHNPGGQPVHLNLVGADEPTVEINVRYRPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUL0</accession>
    <name>D3PUL0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3358</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018594.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3358"/>
    <dbReference type="EnsemblBacteria" id="ADD43023">
        <property type="protein sequence ID" value="ADD43023"/>
        <property type="gene ID" value="Snas_3358"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3358"/>
    <dbReference type="HOGENOM" id="CLU_2234923_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="105" mass="11485" checksum="E21442A3D86923CC" modified="2010-04-20" version="1">MSVPWLADLPSHLRETLDRTEFAPPHSELSALRADLETRTGHLVMTYRLDPAPPRRGSSTLCQLIEAAELTTADAAALSAAEEGARRFGACLVAYRNPLTFKANH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUP1</accession>
    <name>D3PUP1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018625.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3390"/>
    <dbReference type="EnsemblBacteria" id="ADD43054">
        <property type="protein sequence ID" value="ADD43054"/>
        <property type="gene ID" value="Snas_3390"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3390"/>
    <dbReference type="eggNOG" id="COG2850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051161_0_0_11"/>
    <dbReference type="OMA" id="LYWPASY"/>
    <dbReference type="OrthoDB" id="1885303at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="Cupin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="109"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="420" mass="47032" checksum="3F562B1E47B98DE2" modified="2010-04-20" version="1">MKSIDKVPVETHFDWEHFAGNYWNQRPVLYRAVAEPPFEVGEVFAATANACAPVSNGAVPSGVQLTVEREQQRVPGDLLPAASDRDFDGYQDRVTAALDGRRYALTINAFHSHEWRLWHRERRFYRRLWDHVGIPSTSAITTMFHGTYEHSPVGVHKDRFATFMFGLKGDKRMRFWSRKPWTEDVSSVVDYAEYLPSSFVVEVEPGDLLYWPSTYFHVGESGGAPATSVNVGVPHDEHRAVYDTQKFFADIDRDVFTGVTPVSAAMPAVPVDLEATGPDADGLLPDAVPEPLRFAAEVLRQSLDDQRLDERIARASLTCVSAEGLEPPPSPRPRRPLADADVIHAEPEVNVTWTDRDVHGRMVSVNGHTLTTTMEPSRLRGLLRALRAPSPVSELLRDHESEARNVLETLESFGGIRRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUQ0</accession>
    <name>D3PUQ0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SCP-like extracellular</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5290"/>
    <dbReference type="EnsemblBacteria" id="ADD44924">
        <property type="protein sequence ID" value="ADD44924"/>
        <property type="gene ID" value="Snas_5290"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5290"/>
    <dbReference type="eggNOG" id="COG2340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1319134_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="SSF55797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048374" evidence="2">
        <location>
            <begin position="19"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="94"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="211" mass="21908" checksum="39750F43F0D1F027" modified="2010-04-20" version="1">MVATATLVLVTGVGLATAELTIAPDDTKPAADGNAAPTTEAESSSSSSKAEDLDQGKSPTPSKSKTKSPKPSDDEPTTEKPKDEFADLRSGVVDLVNQERANAGCGKVSSNDKLVAAATGHSKDMAANNYFDHTSQDGRTFSDRAAAQGYNSAIGENIAAGQTSAEAVMDSWMNSEGHRANILNCDARAIGMGVAKKSDGTLYWTQMFGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUV0</accession>
    <name>D3PUV0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Malate synthase</fullName>
            <ecNumber evidence="2">2.3.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5340</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.9"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.3.9" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020545.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5340"/>
    <dbReference type="EnsemblBacteria" id="ADD44974">
        <property type="protein sequence ID" value="ADD44974"/>
        <property type="gene ID" value="Snas_5340"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5340"/>
    <dbReference type="eggNOG" id="COG2225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018928_3_0_11"/>
    <dbReference type="OMA" id="MENVRAD"/>
    <dbReference type="OrthoDB" id="322024at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00727">
        <property type="entry name" value="malate_synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1220.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044856">
        <property type="entry name" value="Malate_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011076">
        <property type="entry name" value="Malate_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006252">
        <property type="entry name" value="Malate_synthA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001465">
        <property type="entry name" value="Malate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046363">
        <property type="entry name" value="MS_N_TIM-barrel_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902">
        <property type="entry name" value="PTHR42902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01274">
        <property type="entry name" value="Malate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001363">
        <property type="entry name" value="Malate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51645">
        <property type="entry name" value="SSF51645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01344">
        <property type="entry name" value="malate_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001363-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="537" mass="60282" checksum="F236818C609E2ECB" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUZ1</accession>
    <name>D3PUZ1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5383</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020586.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5383"/>
    <dbReference type="EnsemblBacteria" id="ADD45015">
        <property type="protein sequence ID" value="ADD45015"/>
        <property type="gene ID" value="Snas_5383"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5383"/>
    <dbReference type="eggNOG" id="ENOG50331ZU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156547_0_0_11"/>
    <dbReference type="OMA" id="ESACCSF"/>
    <dbReference type="OrthoDB" id="2057744at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="111" mass="12175" checksum="2AD0FD08171DAD45" modified="2010-04-20" version="1">MDTEINWTPEACTLPTAQQPLRIAEFTSLFVDSLRTVERVAPTRLRLRLDASARDRAVRLTEAESACCTFFTFTISDPTNGQITVDIDVPAAHTEVLDSLAAQATKAGAHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVH6</accession>
    <name>D3PVH6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein-tyrosine phosphatase, low molecular weight</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018661.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3426"/>
    <dbReference type="EnsemblBacteria" id="ADD43090">
        <property type="protein sequence ID" value="ADD43090"/>
        <property type="gene ID" value="Snas_3426"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3426"/>
    <dbReference type="eggNOG" id="COG0394">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071415_3_3_11"/>
    <dbReference type="OMA" id="KPITAHW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="1">
        <location>
            <begin position="5"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="136" mass="14427" checksum="CCE1D193C52ADB17" modified="2010-04-20" version="1">MSGKPEVLFVCVHNAGRSQMAAAILDHLAAGRVAVRSAGSAPAESINPAVVEALAEIGLDVSKEFPKKLSDEAVRASDVVITMGCGDACPVYPGKRYLNWELDDPAGQPVEKVRAVRDDIHVRVRKLLAELDVPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVP4</accession>
    <name>D3PVP4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mandelate racemase/muconate lactonizing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018729.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3495"/>
    <dbReference type="EnsemblBacteria" id="ADD43158">
        <property type="protein sequence ID" value="ADD43158"/>
        <property type="gene ID" value="Snas_3495"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3495"/>
    <dbReference type="eggNOG" id="COG4948">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030273_3_1_11"/>
    <dbReference type="OMA" id="NMAWSET"/>
    <dbReference type="OrthoDB" id="951991at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:cellular amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="Mandelate_racemase_DgoD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="PTHR48080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="1">
        <location>
            <begin position="141"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="395" mass="42327" checksum="CE1468825474F3BD" modified="2010-04-20" version="1">MRITKIRATPVAVPYRTDETWAFGSRSGMVSVLVELDTDEGIVGLGEAAAYPSAEIVLSVLKSVERLVVGADPFRIEQLIQRIDVVGTWHHVKATSPAIAAVEAACWDIVGKACGQPLVNLFGGRFRDSVEFFYYVAAPDPDTVKAEGTRATAAGFTTCYLKVGSDSLDIDIERVAALRDGIGPHMNIRIDANEAWTAGTALRAVRAMLPYGLELVEQPVSGRNLQQLAYVRGRMDVPMLANEACWTRYDQLSVIHNGAADVLSVDNQMDGGLLNLKRSAGLCAAAGMTVLKHSLGELGVALAAATHVIAATPNFRHANQAYGALLSDDIVDGFGGGVDNYRDGCLDVPTGPGIGVALDPDRVARYARLYREHGDTEFSFQHPRALTTGLALPKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW17</accession>
    <name>D3PW17_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5507</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020709.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5507"/>
    <dbReference type="EnsemblBacteria" id="ADD45138">
        <property type="protein sequence ID" value="ADD45138"/>
        <property type="gene ID" value="Snas_5507"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5507"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_9_0_11"/>
    <dbReference type="OMA" id="GWGQDWP"/>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049291" evidence="2">
        <location>
            <begin position="21"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="3">
        <location>
            <begin position="108"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="582" mass="64394" checksum="836DD8DC87B6C9F9" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW36</accession>
    <name>D3PW36_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5526"/>
    <dbReference type="EnsemblBacteria" id="ADD45157">
        <property type="protein sequence ID" value="ADD45157"/>
        <property type="gene ID" value="Snas_5526"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5526"/>
    <dbReference type="eggNOG" id="COG2154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_164085_0_0_11"/>
    <dbReference type="OMA" id="GHTQICL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="123" mass="13828" checksum="1852A1AF92ED963F" modified="2010-04-20" version="1">MTRGEDLLQDALRQLDGWSTDDTRMSRVLTLDESQHASLTEWIKIYADAFEQRPDVSRSDGQTRIAVAGTDGVTLSEVNFAARVEDAYQHIAGITSRGPRSTPHADTPTGALRAWWNRRRDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW51</accession>
    <name>D3PW51_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1504</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016779.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1504"/>
    <dbReference type="EnsemblBacteria" id="ADD41208">
        <property type="protein sequence ID" value="ADD41208"/>
        <property type="gene ID" value="Snas_1504"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1504"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_22_1_11"/>
    <dbReference type="OMA" id="GKPYIAF"/>
    <dbReference type="OrthoDB" id="1238555at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="PTHR43176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ECH_2" evidence="2">
        <location>
            <begin position="22"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="339" mass="36081" checksum="D8CC5C3E7A5323AA" modified="2010-04-20" version="1">MEFHPGRIATDEVGFARHGVLGRIRLHRPKAINALTHAMIAAMLAQLDDWASDASVRAVVIDGEGERGLCAGGDVRQLREAILHEVGDPESFWDDEYRLNAAIADYPKPFVAIMDGVVMGGGVGISAYGSLRLTTPRSKVAMPETAIGFFPDVGGLHPMSRAPGELGTHAALTGLPMTGADAVLCGLADTVVEPADIESIIDALAAGTPPAELALPVPPPAELEAERDWIDACYRGEDAVAIVAALRGRPEPAARRAAEVIASRSPLSVAVTLAAIRKAATMSLAEVLDQDRRLGRHFVTEPDFVEGVRAVLVDRDDNPRWRHDGLADVTADEVARMFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWI9</accession>
    <name>D3PWI9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018782.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3549"/>
    <dbReference type="EnsemblBacteria" id="ADD43211">
        <property type="protein sequence ID" value="ADD43211"/>
        <property type="gene ID" value="Snas_3549"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3549"/>
    <dbReference type="eggNOG" id="COG0272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_333130_0_0_11"/>
    <dbReference type="OrthoDB" id="912694at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="936" mass="103333" checksum="3981C46E37B7F9B7" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWQ9</accession>
    <name>D3PWQ9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic binding protein/LacI transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3621</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018852.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3621"/>
    <dbReference type="EnsemblBacteria" id="ADD43281">
        <property type="protein sequence ID" value="ADD43281"/>
        <property type="gene ID" value="Snas_3621"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3621"/>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_3_3_11"/>
    <dbReference type="OMA" id="SVDGGCT"/>
    <dbReference type="OrthoDB" id="1378040at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049308" evidence="1">
        <location>
            <begin position="29"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="35"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="329" mass="33902" checksum="1FDED3BAE6DE6149" modified="2010-04-20" version="1">MRSAHKPLRLAVTAGLLLATGGLTACSAADDGLKIGLITKTETNPFFVKMKDGAQKAAKEAGAELTTAAGKSDGDNESQVTAIENMITAGVDGILITPNDTEAIVPSIKKARDVGITVIALDTPTEPQDATDALFATDNERAGELIGEYAKALLGDTKPKIATLDLAPGITVGKLRHDGFLKGFGVTDKDPAVVCSQDTQGDQGKGQTAMENCLQSDPDINLVYTINEPAALGAYSAIDAAGKTKDVTIVSVDGGCTGVEAVKDGKIAATSQQYPLDMAAKGVTAIADKVNDGKDVSGYTDTGVNLVTDKPVDGVESKDVEFGLDKCWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXK7</accession>
    <name>D3PXK7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pentapeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018908.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3680"/>
    <dbReference type="EnsemblBacteria" id="ADD43337">
        <property type="protein sequence ID" value="ADD43337"/>
        <property type="gene ID" value="Snas_3680"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3680"/>
    <dbReference type="eggNOG" id="COG1357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100224_0_0_11"/>
    <dbReference type="OMA" id="HGFCVRD"/>
    <dbReference type="OrthoDB" id="985095at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="111"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="266" mass="30870" checksum="4FB02B04A45B698C" modified="2010-04-20" version="1">MTEFHDQDLTGASFERVNLRDASFTRVHLNDARLRAVDLTGVQIRGAMLSRSRMRGVELEDVDISGDLRNVIVNGVDIAPLVEAELNRRYPERAKLRPDDSDGFREAWTILERLWEETLTRARTFPEADLHRSVDDEWSFIQTLRHLSFASAAWVGRMILGDAAPWHPLDLPWDEAPGWDGIPWDRQARPTLDEALAVRRERQAMVRRVMENLTDEQLASEVTRLEPGWPRLEGFPLKECLHIVVMEEWEHRQYAERGLTILDKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXP5</accession>
    <name>D3PXP5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018946.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3718"/>
    <dbReference type="EnsemblBacteria" id="ADD43375">
        <property type="protein sequence ID" value="ADD43375"/>
        <property type="gene ID" value="Snas_3718"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3718"/>
    <dbReference type="eggNOG" id="ENOG502ZBYF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069617_0_0_11"/>
    <dbReference type="OMA" id="WRKPVTF"/>
    <dbReference type="OrthoDB" id="1464866at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="27250" checksum="977889CCD4A82E76" modified="2010-04-20" version="1">MIRELTNKITALWTNGRVVERIGYVVAILAFTSGLFHLIVYAIDGGPWTGPVSWRKPVTFGLSFGIVLATIVWVSTYISIGPKLRTVLVGAFTAASAIEVVGITTQQWRGLPSHFNDEDALSALIGRVGLAGGGAVLIAIVLALTVLSLRPAPQTPPSMRLAVRAGLLILVGAMASGAVMIATGATLSATESHELAYRVSGWLKPTHAVTMHAVTVLPALALLASCLKRDEAWRLRLVKLAVAAYGAAVVITVAVNVALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXS5</accession>
    <name>D3PXS5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018976.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43405">
        <property type="protein sequence ID" value="ADD43405"/>
        <property type="gene ID" value="Snas_3748"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3748"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_11"/>
    <dbReference type="OMA" id="SRPEMIN"/>
    <dbReference type="OrthoDB" id="1054546at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="317" mass="34328" checksum="461F22AD9179E926" modified="2010-04-20" version="1">MRSATLGQLTVSAQGLGCMGMSEFYGPGDWDESIATVRHALDNGVSFLDTADVYGQGHNEVLVGRAIAGRRDEVQLATKFGIDRSAGDHRRVLRGERDYVKRSCEASLLRLGVDVIDLYYVHRPPQDVEIEETVQAMAELKAEGKIRQLGLSEVDASLLRRAHEVHPIAAVQSEYSLWTRDLESEVAPAMRELGVGLVAYSPLGRGFLTGTVDLKSLAGTDFRNRNPRFQSEAAAANAAIVEAVATIAEARDLAPAQIALAWVFAQADRLGVTVTSIPGTKRIKWLDQNIAAMDVTLTDAELATLDPLAAKVVGARY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXU4</accession>
    <name>D3PXU4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA binding S1 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018995.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3767"/>
    <dbReference type="EnsemblBacteria" id="ADD43424">
        <property type="protein sequence ID" value="ADD43424"/>
        <property type="gene ID" value="Snas_3767"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3767"/>
    <dbReference type="eggNOG" id="COG0539">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015805_4_1_11"/>
    <dbReference type="OMA" id="WQQFART"/>
    <dbReference type="OrthoDB" id="1235756at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035104">
        <property type="entry name" value="Ribosomal_protein_S1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="PTHR10724:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="44"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="131"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="217"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="302"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="507" mass="55892" checksum="3D2489781B195EFD" modified="2010-04-20" version="1">MTSSIDAKSSTAAESGDKVVVDDLGSEEALLAAIDETIKYFNDGDIVEGTVVKVDRDEVLLDIGYKTEGVIPSRELSIKHDVDPAEVVSTGDQVEALVLQKEDKEGRLILSKKRAQYERAWGTIEKIKEEDGVVRGSVIEVVKGGLILDIGLRGFLPASLVEMRRVRDLQPYVGRELEAKIIELDKNRNNVVLSRRSWLEQTQSEVRTEFLNKLAKGQVRKGVVSSIVNFGAFVDLGGVDGLVHVSELSWKHIDHPGEVVEVGKEVEVEVLEVDMDRERVSLSLKATQEDPWRQFARTHAIGQIVPGKVTKLVPFGAFVRVEDGIEGLVHISELAERHVEVPEQVVEVGSDAMVKVIDIDLDRRRISLSLKQASEAYVENEEQFDPTLYGMAAQYDDQGNYIYPEGFDAETGEWLDGYDAAREEWERQYADARARWEEHGKQIAERVIKEAPAGAGESADGEKKPAGDKKPAPQQSQSQSAPAEQGPSGTLATDEALAALREKLAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXU8</accession>
    <name>D3PXU8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3771</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3771"/>
    <dbReference type="EnsemblBacteria" id="ADD43428">
        <property type="protein sequence ID" value="ADD43428"/>
        <property type="gene ID" value="Snas_3771"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3771"/>
    <dbReference type="eggNOG" id="COG0411">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="EHDMRFI"/>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="22"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="54"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="294" mass="32208" checksum="06DD93A78ED39DE8" modified="2010-04-20" version="1">MADNLVSETAAPYVDQTGPPLLSVDNVTLKFGGLTALNQVSFEVRKGEILALIGPNGAGKTTCFNVMTGLYRPTAGTVVFDGTKLPGRKPHHITKLGIARTFQSIRLFPEMTAMENVLVGADVHHKTSVVGALFGLPRHRREEREGRAEALRLLDFVGMKHLAGEVARNLSYGYQRRLEIARALATKPKLLCLDEPAAGFNPAEKEELRELIRRIRDLGHTILLIEHDMRLVMGIAERIVVLEFGQKIADAPPAEVRENPKVIAAYLGEPDEDDVDADLMPDRDDQGGSDDGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY61</accession>
    <name>D3PY61_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proline dehydrogenase</fullName>
            <ecNumber evidence="3">1.5.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_5760</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + L-proline = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="7">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 1/2.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020961.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5760"/>
    <dbReference type="EnsemblBacteria" id="ADD45390">
        <property type="protein sequence ID" value="ADD45390"/>
        <property type="gene ID" value="Snas_5760"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5760"/>
    <dbReference type="eggNOG" id="COG0506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061158_0_1_11"/>
    <dbReference type="OMA" id="KWGLRFG"/>
    <dbReference type="OrthoDB" id="1746057at2"/>
    <dbReference type="UniPathway" id="UPA00261">
        <property type="reaction ID" value="UER00373"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:proline catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008219">
        <property type="entry name" value="PRODH_bac_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PTHR13914"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000196">
        <property type="entry name" value="Pro_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pro_dh" evidence="8">
        <location>
            <begin position="42"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="185"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="224"/>
            <end position="225"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000196-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000196-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="306" mass="34564" checksum="ABBF64B213A035CC" modified="2010-04-20" version="1">MLRSIILAAARSSRLERLTATAPVSRNVVKRYVAGTDTNDALRTSRELVDSGLKVSLDYLGEDTLTTDQAESTRDEYLKLLSALKTEGLTPATEVSIKLSALGQRFDEELSLSLAEEICTAAADADTTVTVDMEDHTTTDITLDAVGKLRQRFSGTGAVLQSYLRRTEADCREFAVKNSRVRLCKGAYAEPESVAYQNRLEVDRSYVRCVNTLMSGEGYPMLATHDPRLVEIAIDRAKWYDRGPHSFEFQMLYGIRPDEQRRLAEAGYQVRVYVPFGDQWYGYLMRRLAERPANLRFFMQSLKSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY88</accession>
    <name>D3PY88_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1757</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1757"/>
    <dbReference type="EnsemblBacteria" id="ADD41455">
        <property type="protein sequence ID" value="ADD41455"/>
        <property type="gene ID" value="Snas_1757"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1757"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3899">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006850_0_2_11"/>
    <dbReference type="OMA" id="LPYLPFT"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="924"/>
            <end position="989"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="993" mass="106608" checksum="841E284DCF8427CB" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYA5</accession>
    <name>D3PYA5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M16 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017043.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1775"/>
    <dbReference type="EnsemblBacteria" id="ADD41472">
        <property type="protein sequence ID" value="ADD41472"/>
        <property type="gene ID" value="Snas_1775"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1775"/>
    <dbReference type="eggNOG" id="COG0612">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009902_1_1_11"/>
    <dbReference type="OMA" id="FNGSTHL"/>
    <dbReference type="OrthoDB" id="1188251at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="1">
        <location>
            <begin position="27"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="2">
        <location>
            <begin position="183"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="438" mass="47592" checksum="95733CF4E0D6DE86" modified="2010-04-20" version="1">MTSPQQVDIRAAAFPVEQYRLSNGLRVVLSPDRGVPVVAVAVVYDIGIRLEPQGRTGFAHLFEHLMFQGSANVAKMEHMSYVQGSGGTLNGSTHLDYTDYYEMLPSNALERALFLEADRMRGPAITEENLANQVDVVKEEIRVNVLNRPYGGFPWLKLPPVMFDTFPNAHDGYGSFADLEAATVADAQSFFDTYYTAGNAVLTVAGDFDVAEATAMIERHFADVPGRPAPAHPGIGEPDLTSERRHAYTDPRAPLPAIAAAWRVPDPVKDTKGYLPYVVLAELLTDGDASRLVERMIQKDRTATSLGGYVGFMGEPFAVRDPTALLFQAHLPPGGEPERVLATVDEELRRLASDGLAEGELERVKARIATHVLREDDSVMNRVLRLGTAAALHGDADVARQLPRLLGEVTAAEITQAASLLTPQRRAVVEVIAGGAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYK2</accession>
    <name>D3PYK2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019006.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3778"/>
    <dbReference type="EnsemblBacteria" id="ADD43435">
        <property type="protein sequence ID" value="ADD43435"/>
        <property type="gene ID" value="Snas_3778"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3778"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056342_4_0_11"/>
    <dbReference type="OMA" id="IERPVIW"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="33"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="319" mass="35598" checksum="B438238464B5015E" modified="2010-04-20" version="1">MSRPFASSADLAPKKQTLEILGDGVYALTAEGDPNVGAIEGEDFVVCFDAMATPHAARAWLQQLHHHTDKPVRYLVLSHYHAVRTLGASAFGTDMVIAHDNTRGLIAERGTDDWESEYARMPRLFDNPQSIPGLTWPSITFADKMTIQLGGDRGQLVLAHCGYGHTEGDIVAWLPKQRILFTGDLVEAQAALYTGDAYHRQWATTTLDHVASFEADTLVGGRGACVWGHEEVNAAIGQTRDFLDTMLREVSMVFETDGTLREAFHAVHAALEPRYGGWPIFEHCLPFNVSRLWDELDGINRPRVWTAERDRDIWETLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYL8</accession>
    <name>D3PYL8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019022.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43451">
        <property type="protein sequence ID" value="ADD43451"/>
        <property type="gene ID" value="Snas_3795"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3795"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107911_0_0_11"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="202" mass="22758" checksum="F1CA79E12E66F4BD" modified="2010-04-20" version="1">MNATAGPQNARGARTRAALLEAIHQIVEDEGFEALTMSEVAKRAGVSRRAVYLHFSNRSELIPALHDYVVEVLGLEDSLTRVWDEPDPVAALDEWAGHLVRVHIEAMGVDRTVRSAMHHDPDVADYRAAVGTRQRRNCRMLIENLDAAGRLSSRWDLDTGTDMLWALISTDLLEALYRERGWSKDAIREHLSFLLKRTFVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ02</accession>
    <name>D3PZ02_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5801</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021002.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45431">
        <property type="protein sequence ID" value="ADD45431"/>
        <property type="gene ID" value="Snas_5801"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5801"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_1_11"/>
    <dbReference type="OMA" id="HRCVGAE"/>
    <dbReference type="OrthoDB" id="816674at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="395" mass="43862" checksum="A84DF4A58CB8C7A6" modified="2010-04-20" version="1">MSDEPFNLVMFQRDGLDPVPELARRRAENPVSRVQYPIGPPIWLVTGYEDTRTVLGSNKFSNDFAKMTAEDDLAFLKDVNPGGLGFKDPPDHTRLRKMLTPEFTMRRLRRLIPRIEEIVAERLDAMEAAGDGVDLVDAFAVPIPSLVISELLGVPYPDRADFQRLSESRFDFLGDIEGCLAAVQDTLEYLSGLVAQQRAEPGDNLLGMLVREHGDNISDAELTEIADGILIGGHETTASMLALGALHLMTKPEHFAMVRDDDDKVVPVVDELLRYLTVVQVAFPRFALEDVKLSNGQVVRKGEVVLASLSGANRDSAFGADAEKVNIFRDMPPHVAFGYGLHRCVGAELGRIELQIAYPALLRRFPNLRLAVPFEELKFRELSIVYGVEKLPVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZA1</accession>
    <name>D3PZA1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferric uptake regulator, Fur family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1879</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1879"/>
    <dbReference type="EnsemblBacteria" id="ADD41575">
        <property type="protein sequence ID" value="ADD41575"/>
        <property type="gene ID" value="Snas_1879"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1879"/>
    <dbReference type="eggNOG" id="COG0735">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096072_4_0_11"/>
    <dbReference type="OMA" id="EADVIYW"/>
    <dbReference type="OrthoDB" id="1630127at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="139" mass="15050" checksum="1004D6A8BA46BA84" modified="2010-04-20" version="1">MDSEQLLRQNGLRVTRQRLAVLAVLGEGGHPTVDEIVQRARKRVGSLSTQAVYNVLTMLDDAGLARRIEPAGSNARFEARVGDNHHHLVCRDCGQVEDVDCAVGEVPCLAAADSHGFVIDEAEVIYWGRCPRCAAALSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZB6</accession>
    <name>D3PZB6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">YD repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1894</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017161.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1894"/>
    <dbReference type="EnsemblBacteria" id="ADD41590">
        <property type="protein sequence ID" value="ADD41590"/>
        <property type="gene ID" value="Snas_1894"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1894"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000672_1_0_11"/>
    <dbReference type="OMA" id="TGMERDE"/>
    <dbReference type="OrthoDB" id="1639867at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003284">
        <property type="entry name" value="Sal_SpvB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022044">
        <property type="entry name" value="TcdB_toxin_mid/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022045">
        <property type="entry name" value="TcdB_toxin_mid/N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03534">
        <property type="entry name" value="SpvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12255">
        <property type="entry name" value="TcdB_toxin_midC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12256">
        <property type="entry name" value="TcdB_toxin_midN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01341">
        <property type="entry name" value="SALSPVBPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="TcdB_toxin_midN" evidence="6">
        <location>
            <begin position="660"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="domain" description="TcdB_toxin_midC" evidence="5">
        <location>
            <begin position="877"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="2443" mass="271111" checksum="2AFCC277EE720486" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZB8</accession>
    <name>D3PZB8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase class-III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1896</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017163.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1896"/>
    <dbReference type="EnsemblBacteria" id="ADD41592">
        <property type="protein sequence ID" value="ADD41592"/>
        <property type="gene ID" value="Snas_1896"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1896"/>
    <dbReference type="eggNOG" id="COG0160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_10_0_11"/>
    <dbReference type="OMA" id="PSVGHCH"/>
    <dbReference type="OrthoDB" id="1322538at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="432" mass="45692" checksum="5040D204E1C0FE9C" modified="2010-04-20" version="1">MDTTSRDAADRLLIRYGVGFTPRLIERAAGSHVFDSDGTAILDFTSGQMSAILGHGHPDIVATVSRAVASLDHLYSGMLSPPVLQLAEKLDAALPAPLGKTLLLTTGAEANEAALKMAKLATGRYEIVSFDRSWHGMTQGAASATFSAGRRGYGPPTPGNLVLPTPNGYRSPFRNPDGSYDWEGELDYGFALVDQQSAGSLAACLVEPILSSGGIIDPPPGYLRRLRELCHERGMLLILDEAQTGLGRTGAMYAFERDGVVPDLLTLSKTLGAGLPVAAVVTSDAIERVCHERGFLFYTTHVSDPLAAAVAVTVLDVIEREGLVARAARLGAQLTDRLLALRERFEVVGDVRGRGLLQGLELVRDKKSKAPADELGKAVTAACLERGLHMNIVQLPGMGGIFRIAPPLTIGEAELHSGVDILEAAIAEALGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZN8</accession>
    <name>D3PZN8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019146.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3920"/>
    <dbReference type="EnsemblBacteria" id="ADD43575">
        <property type="protein sequence ID" value="ADD43575"/>
        <property type="gene ID" value="Snas_3920"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3920"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_4_11"/>
    <dbReference type="OMA" id="GWYWENY"/>
    <dbReference type="OrthoDB" id="1616572at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA" evidence="1">
        <location>
            <begin position="2"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="284" mass="29368" checksum="FD0536357EE64628" modified="2010-04-20" version="1">MIVVTGASGPLGRLAIEHLLARGVPAAELAAVVRDPAKAADLAAKGVQLRQADYDKPETLPAALAGADKLLLVSGNAIGQRVAQHTRVVEAAKTAGVGLIAYTSILRADSSGVGLAVEHLASENVVRDSGIPFVMLRNGWYLENYTEHLAPALEHGAWLGSAGTGRAAAAARTDYAEAAAVVLTTEGHSGKVYELAGDTSFDYSELAAEVAAQSGKTVVYRDLPSADHIAALTAAGVPQFMAELMADWDAGVARGDLEDDGKELHKLIGRDTTPLSEAVTAALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZR5</accession>
    <name>D3PZR5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-Lysine 56-aminomutase alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019173.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3950"/>
    <dbReference type="EnsemblBacteria" id="ADD43602">
        <property type="protein sequence ID" value="ADD43602"/>
        <property type="gene ID" value="Snas_3950"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3950"/>
    <dbReference type="eggNOG" id="COG0274">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_517447_0_0_11"/>
    <dbReference type="OMA" id="SGLCMPE"/>
    <dbReference type="OrthoDB" id="346908at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015130">
        <property type="entry name" value="Lys-AminoMut_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037086">
        <property type="entry name" value="Lys-AminoMut_asu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09043">
        <property type="entry name" value="Lys-AminoMut_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lys-AminoMut_A" evidence="1">
        <location>
            <begin position="7"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="525" mass="56893" checksum="03B802E9AA12C1DA" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q011</accession>
    <name>D3Q011_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dCTP deaminase, dUMP-forming</fullName>
            <ecNumber evidence="3">3.5.4.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Bifunctional dCTP deaminase:dUTPase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">DCD-DUT</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dcd</name>
        <name evidence="5" type="ordered locus">Snas_5912</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dCTP + 2 H2O = diphosphate + dUMP + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:19205"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.5.4.30"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dCTP deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.30" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021111.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5912"/>
    <dbReference type="EnsemblBacteria" id="ADD45540">
        <property type="protein sequence ID" value="ADD45540"/>
        <property type="gene ID" value="Snas_5912"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5912"/>
    <dbReference type="eggNOG" id="COG0717">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087476_2_1_11"/>
    <dbReference type="OMA" id="FENHRYP"/>
    <dbReference type="OrthoDB" id="1598407at2"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00667"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033973">
        <property type="term" value="F:dCTP deaminase (dUMP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008829">
        <property type="term" value="F:dCTP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006229">
        <property type="term" value="P:dUTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00146">
        <property type="entry name" value="dCTP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011962">
        <property type="entry name" value="dCTP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02274">
        <property type="entry name" value="dCTP_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="4">
        <location>
            <begin position="67"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="101"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="127"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for bifunctional activity" evidence="3">
        <location>
            <begin position="116"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="196" mass="21828" checksum="B9AEC1F38FECBB5B" modified="2010-04-20" version="1">MLLSDRDIVASMKDGRLGVEPFAPELIQPSSVDVRLDRWFRVFNNQKYTHIDPSKQQDELTSLSEVDEGESFVLHPGEFVLASTLEVITLPDDLAARLEGRSSLGRLGLLTHSTAGFIDPGFSGHITLELSNVANLPISLWPGMKIGQMCLFKLSSPAEHPYGFAEYGSRYQGQRGPTASRAYRNWQTWPTVYDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q078</accession>
    <name>D3Q078_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glu/Leu/Phe/Val dehydrogenase dimerization region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5981</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021178.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5981"/>
    <dbReference type="EnsemblBacteria" id="ADD45607">
        <property type="protein sequence ID" value="ADD45607"/>
        <property type="gene ID" value="Snas_5981"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5981"/>
    <dbReference type="eggNOG" id="COG0334">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025763_0_0_11"/>
    <dbReference type="OMA" id="TYVADMD"/>
    <dbReference type="OrthoDB" id="1184827at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016211">
        <property type="entry name" value="Glu/Phe/Leu/Val_DH_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42722">
        <property type="entry name" value="PTHR42722"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000188">
        <property type="entry name" value="Phe_leu_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="6">
        <location>
            <begin position="145"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="181"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000188-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000188-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="360" mass="38101" checksum="F532B8C8B550CAB1" modified="2010-04-20" version="1">MGVFEAPENLTGHEQVVFCQDKPSGLKAIIAVYSTALGPALGGTRFYPYASEEEAVHDALDLSKGMAYKNSLAGLDLGGGKAVIWGDPETDKSEALLRAYGRFVESLNGRYITACDVGTYVHDMDIVAKETRHATGRSVENGGAGDSSVLTAYGVFCGMRAAAQHRYGTADLTGRTVGVAGIGKVGRHLVTHLIEAGAQVVATDVSEKAHDWLSANHPQASFVDSTEKLIASDIDIYAPCALGGALNDDSVAALRAKIVVGAANNQLAHPGVEKLLADRGILYAPDYLVNSGGVIQVADEIHGFNFDRAKRRASKIFDITGQILRTADTEGVPPAVAADRLAERRMAECGRLRSIHLPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q133</accession>
    <name>D3Q133_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4132</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4132"/>
    <dbReference type="EnsemblBacteria" id="ADD43783">
        <property type="protein sequence ID" value="ADD43783"/>
        <property type="gene ID" value="Snas_4132"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4132"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_35_8_11"/>
    <dbReference type="OMA" id="ALDSLYW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="457"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="2129"/>
            <end position="2206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1811"/>
            <end position="1835"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="491"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="2166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="2277" mass="240884" checksum="B82089626F28B04B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q182</accession>
    <name>D3Q182_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">zf-CGNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021233.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6038"/>
    <dbReference type="EnsemblBacteria" id="ADD45662">
        <property type="protein sequence ID" value="ADD45662"/>
        <property type="gene ID" value="Snas_6038"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6038"/>
    <dbReference type="eggNOG" id="COG5516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087298_2_0_11"/>
    <dbReference type="OMA" id="WCKPSCG"/>
    <dbReference type="OrthoDB" id="1478254at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010852">
        <property type="entry name" value="ABATE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023286">
        <property type="entry name" value="ABATE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021005">
        <property type="entry name" value="Znf_CGNR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35525">
        <property type="entry name" value="PTHR35525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07336">
        <property type="entry name" value="ABATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11706">
        <property type="entry name" value="zf-CGNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160904">
        <property type="entry name" value="SSF160904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-CGNR" evidence="2">
        <location>
            <begin position="153"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="200" mass="22033" checksum="1B37A543DCD9823C" modified="2010-04-20" version="1">MVELLALDLASTIRHDGNGGVTDDLATPEGLTSWVRARSDRLGSWATRFTADDPDWHQVISLRQATRTLLARAVRPGPPSPADAHRLLPLDEAINRVNTAAAQVPTVPHLQWLDDSPPRQRVTAVTAPPTPTLTATLARATIDLLTGPHRPDIRACTAPRCVRYFVKGHGRQEFCKPSCGNRARAARHYRRHRDQTPADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q185</accession>
    <name>D3Q185_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylhydroperoxidase like protein, AhpD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021236.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6041"/>
    <dbReference type="EnsemblBacteria" id="ADD45665">
        <property type="protein sequence ID" value="ADD45665"/>
        <property type="gene ID" value="Snas_6041"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6041"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_6_1_11"/>
    <dbReference type="OMA" id="GCSVCID"/>
    <dbReference type="OrthoDB" id="1893149at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="13"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="152" mass="16499" checksum="8085B3F1DF16324E" modified="2010-04-20" version="1">MNARLNNPMMLLPDLNKPFLHLNKALGTAGVSGSTMELVHLRISQINGCGVCVYGGVDAAKKNGETDERLHSVAIWRESPLFTDAEKAALALAEAGTRIADRPESVSDEIWDNAAKHYDEKQLAALVAFIGLINFVNRVNAITRQEAGVTWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q187</accession>
    <name>D3Q187_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021238.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6043"/>
    <dbReference type="EnsemblBacteria" id="ADD45667">
        <property type="protein sequence ID" value="ADD45667"/>
        <property type="gene ID" value="Snas_6043"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6043"/>
    <dbReference type="eggNOG" id="COG4880">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015706_3_0_11"/>
    <dbReference type="OMA" id="FQGAYVY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019198">
        <property type="entry name" value="Beta_propeller_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014441">
        <property type="entry name" value="UCP006425_b-propeller"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09826">
        <property type="entry name" value="Beta_propel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006425">
        <property type="entry name" value="UCP006425_WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="635" mass="68674" checksum="8AF0294E923C854A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1S5</accession>
    <name>D3Q1S5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0204</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015494.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0204"/>
    <dbReference type="EnsemblBacteria" id="ADD39923">
        <property type="protein sequence ID" value="ADD39923"/>
        <property type="gene ID" value="Snas_0204"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0204"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="OMA" id="VGVTVWW"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="78"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="299" mass="33334" checksum="10345EC4CE924F45" modified="2010-04-20" version="1">MARNPTKAHTRWFTPYVFLAPYLVLFSVFVLAPAVYGLWISLHEWDYMLPSQPWVGLDNYVDLFDSESLVFGDFWSSMSATGIFTVASVPFLVVIPLGIALLLNRKFPGRNVFRAIYFAPYVLGVAVVGLLWRFLLDPNIGGVNYLLGLLGLPDDIAWVNSLPWGWIALVGMTVWWTLGFNAVIYLAGLQDVPRHLYEAAELDGATAWQRFWHVTLPGLRPVTAFVVTVTILASANMFGQSYLVTQGAPGDDTRTAIMYIAEEGLRAFRMGNAAAMGFVLALILGVISVLNFRLLRYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1V4</accession>
    <name>D3Q1V4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017392.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2127"/>
    <dbReference type="EnsemblBacteria" id="ADD41821">
        <property type="protein sequence ID" value="ADD41821"/>
        <property type="gene ID" value="Snas_2127"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2127"/>
    <dbReference type="eggNOG" id="ENOG503279X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061199_2_0_11"/>
    <dbReference type="OMA" id="YEAVTDM"/>
    <dbReference type="OrthoDB" id="1555988at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="208" mass="23744" checksum="6454815A8A68C4DC" modified="2010-04-20" version="1">MGELTVIGASFGRTGTASVRFALEQLGFGPCHHIRHLFASDRHARDWLRVAEGEPADWHRLLFGFAATIAWPASCYWRELAEANPSAKVLLVHRDPSDWYASVARTLYRRRPKRPVAERDRVFERLIWNGVFDGRFTDPRHAMDVYRDHYREVRATIPSDRLIEVDAAKGWPPLCEELGVPVPDETFPHANATGEYPNRPRTTGAVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1Y7</accession>
    <name>D3Q1Y7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MscS Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2161</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017425.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2161"/>
    <dbReference type="EnsemblBacteria" id="ADD41854">
        <property type="protein sequence ID" value="ADD41854"/>
        <property type="gene ID" value="Snas_2161"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2161"/>
    <dbReference type="eggNOG" id="COG0668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021080_0_0_11"/>
    <dbReference type="OMA" id="MPVSYFT"/>
    <dbReference type="OrthoDB" id="1597438at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="365" mass="40283" checksum="864A078DB8D04693" modified="2010-04-20" version="1">MNEIAPAILIPAVAVSVALIASAVRLVVKLLLRKSPRAVEMLTQIYRPTQAMVVLSATRAAINVGQDFQWRAVASHILLLAMFASGAWLANRLLRVARMSVDRVYNRADGSSARRRQRRTQIMVFYRTACALVWIIAVGIMFLTLPGARAIGTSLLASAGVAGVVVGFAAQTMLKNFLAGLGLAFGDTIRLGDAVEIEGEWGHIEDIALSYVVVKIWDERRLVLPTSYFNDHAFRNWSRESADVQGTVDIDVDWRLPVDPIREELTRIVSASSNWDGRKCNLMVSESVGPLKRLRPLVSANDGEVLWDLRCEVREKLIDFIVANYPDCVPGLRVETHGSPQESRITAILPLQPTRHDGHGPVSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2B5</accession>
    <name>D3Q2B5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4198"/>
    <dbReference type="EnsemblBacteria" id="ADD43848">
        <property type="protein sequence ID" value="ADD43848"/>
        <property type="gene ID" value="Snas_4198"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4198"/>
    <dbReference type="eggNOG" id="ENOG50331DK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129731_0_0_11"/>
    <dbReference type="OMA" id="KTGYPQR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="111" mass="12946" checksum="38A6722C93164ACB" modified="2010-04-20" version="1">MSWFRRKKRTGTSDRGAERMDTSHLEQFHATRQGVEAYVEPRTNMTETTVMLIAHDGEWTRRRVDGTEAAFSLGDRLGIPVYEVAKVGYPQRMRDYNARQRKLKEGRSTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2E3</accession>
    <name>D3Q2E3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019447.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4227"/>
    <dbReference type="EnsemblBacteria" id="ADD43876">
        <property type="protein sequence ID" value="ADD43876"/>
        <property type="gene ID" value="Snas_4227"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4227"/>
    <dbReference type="eggNOG" id="ENOG502ZC7X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053841_0_0_11"/>
    <dbReference type="OMA" id="RWLRDYD"/>
    <dbReference type="OrthoDB" id="1110894at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024659">
        <property type="entry name" value="Phage_coat_Gp5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11651">
        <property type="entry name" value="P22_CoatProtein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="322" mass="35269" checksum="919BD62B806B69FF" modified="2010-04-20" version="1">MNNQFLKPSVIAATALGLLERDIVLPGLVWRDAVESFDGADDDTVSIRVPARTKAQRRRMRVEPRGKIVAKKLKETKVDVTLTEHVISAIDVTDEEMTLDITNFGAKILAPQTRAIAEDLENQIAETMAAAPYETELTLDVAHPEDTFVDARRALNVESVPVADRVAVVGADVEAAILKADGLTRVDKSGDNTALRNAEIGKLRQFPVYLSNAIDPGTAYLFHRTAYVFALRAPIVPDGAPFGQSQSYGDLAMTWVRDYDSDYMQDRSIVHTFSGTAFVPDPPRDKTPETTDPKKFVRAVKITMPDTVALPAPKPGRKKAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2K1</accession>
    <name>D3Q2K1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4285</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019505.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4285"/>
    <dbReference type="EnsemblBacteria" id="ADD43934">
        <property type="protein sequence ID" value="ADD43934"/>
        <property type="gene ID" value="Snas_4285"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4285"/>
    <dbReference type="eggNOG" id="COG2271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040020_1_0_11"/>
    <dbReference type="OMA" id="GYGLFWF"/>
    <dbReference type="OrthoDB" id="1345431at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="27"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="412" mass="41762" checksum="8FE6E2DCC3D32C18" modified="2010-04-20" version="1">MYLSATRAADSARTTTATPAARRVGGTVIALGLVSLVTDMSAEMITAILPMYLMYGLGLGYLHLGMLDGLYTGATALLRLGGGFAADRLNRPKAVALSGYGLSAATKLGFPLVGASLGGIGTLVGLDRAGKGIRTAPRDALITAATAPEALGRAFGVHRALDTAGALLGPLLAFALLAGVAGGYDQVFVVSFCLAVVGVLILAFFVNNPPAAPGHRRATVRAALSAVTDARLRRVWLATGILGVATVGDMFLYLAIQRQLGLPPQALPLLPLGSALTFMLAAAPVGRVADRLGRWRVFLAGHLLLLGGYLALTGTASGWPIAVAVLAMHGVFYACSDGVLMAHIGPSIPDSVRATGMAVIQTTQALARAGGAVVFGIVAQTVALSTAFGFAAAALAAAVTASAVLCLRKPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2P2</accession>
    <name>D3Q2P2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA synthetase</fullName>
            <shortName evidence="7">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">serS</name>
        <name evidence="9" type="ordered locus">Snas_6170</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6170"/>
    <dbReference type="EnsemblBacteria" id="ADD45793">
        <property type="protein sequence ID" value="ADD45793"/>
        <property type="gene ID" value="Snas_6170"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6170"/>
    <dbReference type="eggNOG" id="COG0172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023797_0_1_11"/>
    <dbReference type="OMA" id="SPCFRRE"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="PTHR11778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="139"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Serine binding" evidence="7">
        <location>
            <begin position="230"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="260"/>
            <end position="262"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="347"/>
            <end position="350"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="422" mass="46857" checksum="FD4C7EFC26E595BA" modified="2010-04-20" version="1">MSVLVIDLRTVRENPDLIRRSQQVRGESEQVVDDLIAADTANREALARFETLRAEQKQLGKRVSRASGDEKQELLVRTKELSGEVKTAEAAVNAAAETLRAAQLAVPNIVEEGVPAGGEDDFVVLREVGERKVPETCRDHLELGEILGAIDMERGAKTSGSRFYYLVGMGALLQQALLNLALQQAVETGFTPMIPPVMVRPEAMEGTGFLGAHASEVYYLEDEELYLVGTSEVPLASYHAKEILDLEQPKRYAAWSSCFRKEAGSYGKDTRGIIRVHQFDKIEMFSYCRPEEAAAEHERLLGFEERMLAKIEVPYRVIDTAGGDLGSSAARKFDCEAWIPSQERYRELTSTSNCGTFQARRLGTRYRDENGKPQTAATLNGTLATTRWIVAILENHQQPDGSVRVPEALRPFLGREVLEPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Y3</accession>
    <name>D3Q2Y3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0234"/>
    <dbReference type="EnsemblBacteria" id="ADD39953">
        <property type="protein sequence ID" value="ADD39953"/>
        <property type="gene ID" value="Snas_0234"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0234"/>
    <dbReference type="eggNOG" id="ENOG50309SY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_816167_0_0_11"/>
    <dbReference type="OMA" id="WISDVIY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="337" mass="35344" checksum="18FE21CB69CD3DAD" modified="2010-04-20" version="1">MRRNNGSLPPAISLFFLTPVIAEFLPGYLSLDSLVTALVLAPMYGGGALLIRELTRRAGRGWWTILILGLAYGVVEEGFGTQSLFNPHYADLELLQPAHLPGLGMGAWWTVFVVALHAVWSIALPIAIVEAFTASRPRQPWLGRIGLTVTALVFALGVAVIASFTMAGDDFRATPGQFIGAAVAVVLLATLALTLGGKLDAQTLAERAAPPVWLVTALSLLAGAAFAGSAFLVSSGGADQLGWPLVLGYLVLVALMVTIVRHWSVSPDWGDAHRLALAGGALLTYAANAFIETPSTPVDPALDLAGNLGFALGAVVLLLLATRRVSNTALRPQRVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q346</accession>
    <name>D3Q346_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015587.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0298"/>
    <dbReference type="EnsemblBacteria" id="ADD40016">
        <property type="protein sequence ID" value="ADD40016"/>
        <property type="gene ID" value="Snas_0298"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0298"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_11"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="245" mass="25012" checksum="BD2BBC777C96810E" modified="2010-04-20" version="1">MTTVNTTAKPFDGKTVVVTGGAGGIGHAVSEAFTDAGAHVVTVDLTGADHDLDVTDAAALTRAMADVNARHGGPHVLVALAGGSLGIPRDLDAFTDEQFNKVLDVNVTGTLNACRAALPYLKQAKGSIVTCTSIGARQPSPVTGVAYAAAKAAIGGLTRRLAAEVGPDGVRVNALAPGLVLTPRLSGMFDGLSQSDRDSVTEAIALRRMPELREIVDPILFLAGEGAGYITGVTLDVNGGRYMPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3C5</accession>
    <name>D3Q3C5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane-associated protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2277</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DedA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017537.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2277"/>
    <dbReference type="EnsemblBacteria" id="ADD41966">
        <property type="protein sequence ID" value="ADD41966"/>
        <property type="gene ID" value="Snas_2277"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2277"/>
    <dbReference type="eggNOG" id="COG0586">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044208_2_0_11"/>
    <dbReference type="OMA" id="WLGATWL"/>
    <dbReference type="OrthoDB" id="1928533at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032818">
        <property type="entry name" value="DedA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30353">
        <property type="entry name" value="PTHR30353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="197" mass="21360" checksum="48D79DC70FA52452" modified="2010-04-20" version="1">MWPDIDHLLASPWVYLVVMALIMCDVYLPVLPSGTSLIVATVYAHTGATNELALLGCAALASTTGDWLAFRLASRGSGRLRARLARRPSLARADDRLRSMLRHHTGRSVVFARFVPAGRCVVTFACGSDPDISARRFQPWSAVAAICWATYTVGLGYLNALLFHTTWISAVVAVVALFTVGMLLARTRPATELVKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3F1</accession>
    <name>D3Q3F1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2303</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017563.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2303"/>
    <dbReference type="EnsemblBacteria" id="ADD41992">
        <property type="protein sequence ID" value="ADD41992"/>
        <property type="gene ID" value="Snas_2303"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2303"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_34_3_11"/>
    <dbReference type="OMA" id="MSFNYVV"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="10"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="463" mass="47239" checksum="24CE291AB49D2DD6" modified="2010-04-20" version="1">MSAALTRSPARLLVPALVFIALVVAAVASLGMPLITSVATTFHVSLDSAQWTLTITLLSGAVATPVLGRLGTGRHRRATILATLAIVVVGSALTVLPLPFAWLLVGRAAQGIGLGLTALMMGVARDHLPEKRGAATIALISVVSIIGAGVGYPLAALLAEFGGLRAAYGLGLLVTAIALLTAWRSIPAAPEGRFAHVNVAGALVLAGGLFLVLFLAGERSLWGRHLAVAVSLAVAAVLLLCLWTASELRSTTPLVDVRAVRHPAVAGANIAMFVGGSGMYLLLTLITRYAQTPHSAGYGFGLSTFVAGLVLIPFSVLGFVAGKLTQRVRERIDGPLLLAGSAAIVGGGFVLFAVARSNLAELLVAMGLLGFGVGGFSAAMPGVILAVTPKSETSSAMSFNYVVRSVGYSLGSAIGGLVLAVGTGRLFPNEAAYTTAALLGVAAMAITTMTSLALARRRSRPRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3K9</accession>
    <name>D3Q3K9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA ligase</fullName>
            <ecNumber evidence="9">6.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Polydeoxyribonucleotide synthase [NAD(+)]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ligA</name>
        <name evidence="11" type="ordered locus">Snas_2365</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the NAD-dependent DNA ligase family. LigA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017621.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2365"/>
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        <location>
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        <location>
            <begin position="46"/>
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        <ligand>
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        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
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        <source>
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        <source>
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        </source>
    </evidence>
    <sequence length="749" mass="81867" checksum="7F292FA3382D8001" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Q5</accession>
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        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
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        <name evidence="3" type="ordered locus">Snas_4325</name>
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        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
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            </authorList>
            <dbReference type="PubMed" id="21304662"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
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        <property type="entry name" value="TetR_N"/>
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        <property type="entry name" value="HTH_TETR_2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ADD43972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="19984" checksum="1E93BBBFB27E069A" modified="2010-04-20" version="1">MGRREIAVAALRLLNAKPTASMADIAAAAGVSRATLHRHFAGREELVRLLGELSIESWREALDNADIDTATASGDAAQLRSALEVLCGQLVRDAYEHGFALTEPSFETDDEMVAASEVQQNRELAFYAAAQKAGVVRDDMSATWIAHAVFGLLVGLREALRRGDIAVRDAERLLRETVFGGIAVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3R8</accession>
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        <recommendedName>
            <fullName evidence="1">zf-CGNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ordered locus">Snas_4338</name>
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    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
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                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
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            <dbReference type="DOI" id="10.4056/sigs.47643"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
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        <property type="entry name" value="ABATE"/>
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        <property type="entry name" value="ABATE_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Znf_CGNR"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11706">
        <property type="entry name" value="zf-CGNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160904">
        <property type="entry name" value="SSF160904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-CGNR" evidence="1">
        <location>
            <begin position="138"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="182" mass="19663" checksum="40015D4B693B8D1A" modified="2010-04-20" version="1">MHVNATTDGFQPAQRLVDLANLVRHDPSASRERLAELLATHGESAAELASLTARDAERLRATATALGDVLALTDVDAAAHALNALLDEHSAHPRLSNHDGHAWHLHVERDSGWDTWLAASGALALAQLLTERGRLAWGECAAEGCRNLFLDDGPGSPRRYCTTKCASRARVAEHRARKRTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4D1</accession>
    <name>D3Q4D1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0374</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0374"/>
    <dbReference type="EnsemblBacteria" id="ADD40091">
        <property type="protein sequence ID" value="ADD40091"/>
        <property type="gene ID" value="Snas_0374"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0374"/>
    <dbReference type="eggNOG" id="COG2944">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_737489_0_0_11"/>
    <dbReference type="OMA" id="LHRQACF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="361" mass="40217" checksum="60DAAD442661A49F" modified="2010-04-20" version="1">MKQEPRAYGGISGFMLKVARQSIPVSQEAFAETLAVDPTTVQSWESGRRPLGAATMTQVRRLGRQLLRLGVDSELVAMIPVAIEADLIITAIATPVPDGELGQHPLAGCVMDLRISELLTWALTGVPPRIASRIPPVRRRGPAPTRPELGWIDRKQLNANLLQLSDRGEQDGSTLLLRSQACFLTGLARLDTPAKLSTAASRYLVGGESWSPSWLDARSHVVSCAYRGDPEPLRRFITHAQESDDCETAALNYTAYWVGDMPDREGDDGFMPRNLLRWRGSRMYPHLVERLQTTHPLIDLNTHNLWLLLRSQRGLIIDDKQTSLLLLDRIDEAADSNRVSQQSLRELRSMKSALAELGYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4F2</accession>
    <name>D3Q4F2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015683.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0395"/>
    <dbReference type="EnsemblBacteria" id="ADD40112">
        <property type="protein sequence ID" value="ADD40112"/>
        <property type="gene ID" value="Snas_0395"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0395"/>
    <dbReference type="eggNOG" id="ENOG502ZX7Q">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2036606_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="121" mass="13208" checksum="CCC833CE57A20886" modified="2010-04-20" version="1">MPPPPPTDGRFEVDVDAIEDFQPTFNRLDSRVSTASGKVSPASAEGLGTFTDAMTVIRDHDRLRATYLTRLEMLRAAVAIANTKTTRLIANYRGTESTETSNMTALLGPLANVIQQIARKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Q1</accession>
    <name>D3Q4Q1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2398</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2398"/>
    <dbReference type="EnsemblBacteria" id="ADD42081">
        <property type="protein sequence ID" value="ADD42081"/>
        <property type="gene ID" value="Snas_2398"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2398"/>
    <dbReference type="HOGENOM" id="CLU_2810353_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="67" mass="7551" checksum="1B20C8CC6D802A01" modified="2010-04-20" version="1">MVRVGSSTATVGRTRLIGPAKVENFGVRFKVGEGFRDEVTILAGRRNLHREDLLAQLNAFDWPMEYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4S6</accession>
    <name>D3Q4S6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protoheme IX farnesyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Heme B farnesyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Heme O synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ctaB</name>
        <name evidence="8" type="ordered locus">Snas_2423</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(2E,6E)-farnesyl diphosphate + H2O + heme b = diphosphate + Fe(II)-heme o</text>
            <dbReference type="Rhea" id="RHEA:28070"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.141"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Porphyrin-containing compound metabolism; heme O biosynthesis; heme O from protoheme: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.141" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017677.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2423"/>
    <dbReference type="EnsemblBacteria" id="ADD42106">
        <property type="protein sequence ID" value="ADD42106"/>
        <property type="gene ID" value="Snas_2423"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2423"/>
    <dbReference type="eggNOG" id="COG0109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029631_0_1_11"/>
    <dbReference type="OMA" id="QFFWQFP"/>
    <dbReference type="OrthoDB" id="1875497at2"/>
    <dbReference type="UniPathway" id="UPA00834">
        <property type="reaction ID" value="UER00712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048034">
        <property type="term" value="P:heme O biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PTHR43448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="341" mass="36580" checksum="09410D015D3D8387" modified="2010-04-20" version="1">MRRNPTAAAGVTVPVHRIAESPTRPIIIDTGRQAPAPETAPTPRRGTGAAAVLKAYVALTKPRIVELLLITTVPAMLLAARKATGGLPEVWTVVAVVIGGALAAGSANALNCFLDRDIDQLMRRTSRRPLPQHTVSPRSALVFGLVLGVVSVTAIGLVTNLLAAGLTLAAIAYYDLIYTLWLKRTTAANTVWGGVCGAAPVLIGWAAVTGGLSWEAWILFAVVFFWQPPHFWALAVKYKDDYAAAGIPMLPVVASARRVGLESVIYAWLTLVSSLALWPLATTPLYGIVAAATGLMFCVEAHRMHGRARRDEDLKPMRLFHWSTSYLTLLFVALAVDSFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4T6</accession>
    <name>D3Q4T6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017687.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2433"/>
    <dbReference type="EnsemblBacteria" id="ADD42116">
        <property type="protein sequence ID" value="ADD42116"/>
        <property type="gene ID" value="Snas_2433"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2433"/>
    <dbReference type="HOGENOM" id="CLU_183045_2_0_11"/>
    <dbReference type="OMA" id="LAWIVMW"/>
    <dbReference type="OrthoDB" id="2071349at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021741">
        <property type="entry name" value="DUF3311"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40034">
        <property type="entry name" value="PTHR40034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11755">
        <property type="entry name" value="DUF3311"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="77" mass="8540" checksum="A37667B97165D339" modified="2010-04-20" version="1">MKLRIAITSLPFIGLLVGIHFANRATPYVLGLPFIVFYVAFWVVMCAVLMGLLTWLDDRAERKARETSAADAGRDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4W7</accession>
    <name>D3Q4W7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2464</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017718.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2464"/>
    <dbReference type="EnsemblBacteria" id="ADD42147">
        <property type="protein sequence ID" value="ADD42147"/>
        <property type="gene ID" value="Snas_2464"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2464"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029425_12_3_11"/>
    <dbReference type="OMA" id="LYGHINT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048661" evidence="2">
        <location>
            <begin position="45"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="3">
        <location>
            <begin position="126"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="231" mass="24074" checksum="C7AFBCFA95F199EE" modified="2010-04-20" version="1">MDTPHPKKPSRYLGRHRHPFLTRTVFAALATATVLGTGLTAASAAPPHDDAPAVAEESTDAKPESDPSIEPEPTPSEEDSSSAKPEETKDKPKANDAEKQQPSWVVPSADGISDVFGPRGWRGGEMHNGLDFAAEEGDENFAAADGTVVQAGSNGGYGLSVTIDHGNGVETLYGHHSQLSVQVGDKVSAGDVIGLAGSTGDITGPHLHFEVHVDGEPVDPAAYLEKKGVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q501</accession>
    <name>D3Q501_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2499</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017752.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2499"/>
    <dbReference type="EnsemblBacteria" id="ADD42181">
        <property type="protein sequence ID" value="ADD42181"/>
        <property type="gene ID" value="Snas_2499"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2499"/>
    <dbReference type="eggNOG" id="ENOG5032EQ4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086002_1_0_11"/>
    <dbReference type="OMA" id="LESVHWR"/>
    <dbReference type="OrthoDB" id="1407012at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="27116" checksum="D02D01AACE823720" modified="2010-04-20" version="1">MTVPVLLSARLVPWLRAWRAGMTSLDDVVEAMTSEGMSGVEQIVVTEAEIGPGATLTEGFSRLSGVDTEDIRLVLAVPGDARGLPTAGPFAAAALTAGEAVVAGRNGLVPERRAHTSGSGSTWETVLWHHFELDAVPVPADLVSPGEADASLTQALRAATKVLSDLDVAAWNPELGRALAGARTDSGRQLPPGFDTRSRRLYARAVMLERVLRVADSDAMGGAVTAHEAAARLEALRGLAASCRTAIGAACHARLHCGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5F3</accession>
    <name>D3Q5F3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chitinase</fullName>
            <ecNumber evidence="7">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_6397</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021584.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6397"/>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD46013">
        <property type="protein sequence ID" value="ADD46013"/>
        <property type="gene ID" value="Snas_6397"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6397"/>
    <dbReference type="eggNOG" id="COG3325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002833_14_4_11"/>
    <dbReference type="OMA" id="HRLLGQQ"/>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="SSF54556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048881" evidence="5">
        <location>
            <begin position="27"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="6">
        <location>
            <begin position="38"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD46013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="430" mass="46465" checksum="ED00DF6E1C83CA49" modified="2010-04-20" version="1">MKRPFPVLAALAAATALLLPTGAAVAAEPDADDPKSGGRSVGYFTQWGVYDRGFLVKDIVDSGQVNNLTHINYAFGNVNEQGRCFEANQAGVGDAWADYQRRYTAAESVDGVADTYDQPLAGNFNQLKELKAAHPDLKILFSLGGWTWSKYFSNAALPENREAFVSSCIDMFIKGNLPKIGGEPQGGDGVAAGIFDGFDLDWEWPGSPGNDGNVIRPEDKQNYTALVAEFREQLDALGDGYELSAFVPADPEKVEAGFEVPQLMENFDFVNVQGYDLAGAWDPTTNHQAQIHSPADNPNPAKWSSDLAIQTWKNAGAPADKLVLGLPAFGRGWTGVGSANNGLYQTSTGPAPGKYEPGIDDYKLVKDKPGQVFRDEENMAVWKYDGTQFWSYDDPAMIAKKMSYIAEQGLGGAMIWSLDGDDGTLVAEMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5J7</accession>
    <name>D3Q5J7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_6441</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021628.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6441"/>
    <dbReference type="EnsemblBacteria" id="ADD46057">
        <property type="protein sequence ID" value="ADD46057"/>
        <property type="gene ID" value="Snas_6441"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6441"/>
    <dbReference type="eggNOG" id="COG2015">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014655_1_0_11"/>
    <dbReference type="OMA" id="NPARLWP"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018741">
        <property type="term" value="F:alkyl sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018909">
        <property type="term" value="P:dodecyl sulfate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07710">
        <property type="entry name" value="arylsulfatase_Sdsa1-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038536">
        <property type="entry name" value="Alkyl/aryl-sulf_dimr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029229">
        <property type="entry name" value="Alkyl_sulf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029228">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044097">
        <property type="entry name" value="Bds1/SdsA1_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14864">
        <property type="entry name" value="Alkyl_sulf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14863">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="5">
        <location>
            <begin position="88"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD46057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="611" mass="66401" checksum="76333A28A5B55949" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5L6</accession>
    <name>D3Q5L6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021647.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6461"/>
    <dbReference type="EnsemblBacteria" id="ADD46076">
        <property type="protein sequence ID" value="ADD46076"/>
        <property type="gene ID" value="Snas_6461"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6461"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124277_3_0_11"/>
    <dbReference type="OMA" id="HEFPFLF"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="21"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD46076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="144" mass="15997" checksum="6C4603FCEDF20247" modified="2010-04-20" version="1">MNDAGLTPRQVWERSVWYGMQGDIDAQLALYAPDCVIEFPFVAEPVPNRFTGRDEIRDMIVRLRAATPAAENQPVQSESTVVVHETADPEVIIPEFTVAMANSGTGEVVKSSYVQVIRVRDGLITSIRDYFSPATVEDVRRALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5L7</accession>
    <name>D3Q5L7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ADD46077"/>
        <property type="gene ID" value="Snas_6462"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6462"/>
    <dbReference type="eggNOG" id="COG1691">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_065705_0_0_11"/>
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    <dbReference type="OrthoDB" id="1744359at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="P2CMN_synthase_LarB"/>
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        <property type="entry name" value="PurE_dom"/>
    </dbReference>
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        <property type="entry name" value="PTHR43064"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="1">
        <location>
            <begin position="126"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD46077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="26245" checksum="46824963744FFF56" modified="2010-04-20" version="1">MDNEAIRSLLEAVASGESSVTEAARRLTDGVFADGPGYAELGFAKVDTHRPLRTGEPEVVYGAGKTVDQVLSITARLRQAHPEHPILVTRASDETRAALRSTSEPVTEDPLAAIVAIGALPTPNLGTVAVLCAGTSDLPVATEAAFTARAFGLSVVEISDVGVAGLHRLLAARETLATADCVIVVAGMDGALPSAVGGLVAVPLIAVPTSVGYGAAFGGLAPLLTMLNSCAPGVSVVNIDNGFGAAVCAARIVRTKGALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5Q0</accession>
    <name>D3Q5Q0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
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            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0484"/>
    <dbReference type="EnsemblBacteria" id="ADD40199">
        <property type="protein sequence ID" value="ADD40199"/>
        <property type="gene ID" value="Snas_0484"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0484"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010663_0_0_11"/>
    <dbReference type="OMA" id="KIEREYW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1168"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1182"/>
            <end position="1201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1201" mass="131083" checksum="5E3D960664071BA5" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5T9</accession>
    <name>D3Q5T9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ADD40238"/>
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    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_3189274_0_0_11"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="46" mass="4880" checksum="48F196C722C700F1" modified="2010-04-20" version="1">MTINSTPTVPPQAASIEAVPAGNAHPGASPRPKRYHGRHRRPRNAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5Z4</accession>
    <name>D3Q5Z4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PAS/PAC sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0579</name>
    </gene>
    <organism evidence="3 4">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
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                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
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            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0579"/>
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        <property type="protein sequence ID" value="ADD40293"/>
        <property type="gene ID" value="Snas_0579"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_2_11"/>
    <dbReference type="OMA" id="AMLAFRW"/>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
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        <property type="entry name" value="HisK_dim/P"/>
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        <property type="entry name" value="HisK_dim/P_sf"/>
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        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
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        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BCTRLSENSOR"/>
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        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="160"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="401" mass="42423" checksum="EF4C094FC11D0468" modified="2010-04-20" version="1">MTFSNVPRAGRAAATFAVGLAAGAAAGYALNGRRRTLEPASDEEFSRTQVGAWHKVFEALRTGVCVVDADNQVTYANTGARALGVDAETELEPASLRSLAEHVRATGAPRQVELELNQGGDPTAVRVDVAPLPDGHVAVELTDISELHRVERVRRDFVANVGHELKTPVGALQLLAEALADAVDDPAAAARFTTRIQHESARMSRLVSELLELSRLQGAEPMPAPVTVWIDRVVNEAVDRGRTAASAKDITINRTGRRRLAVSGSENQLATALGNLVGNAIAYSPEGTSVTVDTTVKDDSVLIAVTDEGIGIDPSEQHRIFERFYRSDPARSRATGGTGLGLAIVKHIAGNHGGRVDVSSMPGNGATFTLTLPSVTADADEAELSPGEIDTLTTHIEEGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q664</accession>
    <name>D3Q664_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017810.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2559"/>
    <dbReference type="EnsemblBacteria" id="ADD42239">
        <property type="protein sequence ID" value="ADD42239"/>
        <property type="gene ID" value="Snas_2559"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2559"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048109_0_0_11"/>
    <dbReference type="OMA" id="WEPLAIM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="119"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="247" mass="26734" checksum="0CB5BAB73B94D47B" modified="2010-04-20" version="1">METIRIVQEAAARAMPPDHVEWLDGWLLRYTTSKSWWAGSVLAHGEPSSGEMMRRIIAAEEFYAGHGTAARFQISPPVSSPGLDDALAARGYGRSGQMSLQSADTATIVGNAPDTPLRIVVDEKPTSAWFDVWQTTHDVDPAAERAMCERVRQPVGYVRVLADGEAIAVGRAVADDGWAGVFGMATLPAARGKGAARTVLAALAEWAGRNGADRMYLQVEGDNDAALRLYGRMGFRELCGYHYRIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6M4</accession>
    <name>D3Q6M4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4624</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019838.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4624"/>
    <dbReference type="EnsemblBacteria" id="ADD44267">
        <property type="protein sequence ID" value="ADD44267"/>
        <property type="gene ID" value="Snas_4624"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4624"/>
    <dbReference type="eggNOG" id="COG0295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151846_0_0_11"/>
    <dbReference type="OMA" id="ARNQVPE"/>
    <dbReference type="OrthoDB" id="2043951at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="108" mass="10783" checksum="8FBB764DE899DC0B" modified="2010-04-20" version="1">MTAPLDAEDQKLVTLARAAASRIGASSAGAVRDDDGRSYVAASISLPSLQLTGLQLAVAQAAAAGAETLEAAIFLGTTDAPGTAAVRDLSRSAPIYAVDGTAIRKLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6P5</accession>
    <name>D3Q6P5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4645</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4645"/>
    <dbReference type="EnsemblBacteria" id="ADD44288">
        <property type="protein sequence ID" value="ADD44288"/>
        <property type="gene ID" value="Snas_4645"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4645"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_3_11"/>
    <dbReference type="OMA" id="LWYSVQS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="80"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="299" mass="32291" checksum="3E6CC3C102ABAFCB" modified="2010-04-20" version="1">MTATKEAAPISDAKAAERRLGWLLCAPAAIVMLAVAGWPILLSIITSFQRSDLRFPDDKGFVGFANYATVLTSEHWWTAFGVTMLIMVVSVAVELVLGMGLAVVMHRTLVAKGLLRTTVLIPYGIVTVVAAYGWQYAWTPDTGWLAGLLPEGSAPLTERWPALLIIIGAEIWKTTPFMALLLLAGLSVVPDELHRAASMDGAGRWQRFVKVTLPLMKPAILVALLFRMLDAFRIYDNIYVLTNGAQDTASVSITTYHNLVSGLNLGIGSTMSVLIFVTVAIIAFIFVKGLGTSTPEGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6S2</accession>
    <name>D3Q6S2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0607</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015892.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0607"/>
    <dbReference type="EnsemblBacteria" id="ADD40321">
        <property type="protein sequence ID" value="ADD40321"/>
        <property type="gene ID" value="Snas_0607"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0607"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="VRDPLNV"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="216" mass="23220" checksum="089531511A04998F" modified="2010-04-20" version="1">MTIRVTVADDQAMVRSGLRFILEDQPDITVVGEAADGVEAIELARRVRPDVCVVDIRMPRLDGIAVTRALAGPGVVDPLRVLIVTTFDLDEYVYGALRGGAVGFVLKDAGPVLLVEAVRAANAGNALISPSITLRLLSHLAPGAGEPEPDHRLSDRELEVVRAIAIGRTNQEVAAELFISLSTVKSHVSSIQAKLGARNRVAIAAWAWEHRVVDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6S9</accession>
    <name>D3Q6S9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional purine biosynthesis protein PurH</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Phosphoribosylaminoimidazolecarboxamide formyltransferase</fullName>
                <ecNumber evidence="8">2.1.2.3</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">AICAR transformylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">IMP cyclohydrolase</fullName>
                <ecNumber evidence="8">3.5.4.10</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">ATIC</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">IMP synthase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">Inosinicase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="8" type="primary">purH</name>
        <name evidence="10" type="ordered locus">Snas_0614</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6S)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The IMP cyclohydrolase activity resides in the N-terminal region.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PurH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.3" evidence="8"/>
    <dbReference type="EC" id="3.5.4.10" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015899.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0614"/>
    <dbReference type="EnsemblBacteria" id="ADD40328">
        <property type="protein sequence ID" value="ADD40328"/>
        <property type="gene ID" value="Snas_0614"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0614"/>
    <dbReference type="eggNOG" id="COG0138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016316_5_2_11"/>
    <dbReference type="OMA" id="WRVAKFV"/>
    <dbReference type="OrthoDB" id="1049662at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="PTHR11692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="9">
        <location>
            <begin position="5"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD40328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="518" mass="55070" checksum="AFBF471616C9D99A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Y0</accession>
    <name>D3Q6Y0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">O-methyltransferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0666</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015950.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0666"/>
    <dbReference type="EnsemblBacteria" id="ADD40379">
        <property type="protein sequence ID" value="ADD40379"/>
        <property type="gene ID" value="Snas_0666"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0666"/>
    <dbReference type="eggNOG" id="COG3315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069348_2_0_11"/>
    <dbReference type="OMA" id="LQYHRYA"/>
    <dbReference type="OrthoDB" id="847145at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016874">
        <property type="entry name" value="TcmP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028177">
        <property type="entry name" value="Polyketide_synth_Omtfrase_TcmP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="265" mass="30629" checksum="83C2E01E6F4DDAE2" modified="2010-04-20" version="1">MDDDRVELAGVKETMLFTLYCRDRDNRSRQPVLGDSHASRIIDSVYDRIPLKLRIASGDRYVVTLRARRLDGWTREFLATNPDAVVLHLACGLDSRAFRLDVPATVDWIDLDFPEIIELRRQLYPPRPGYRVIAASVTDPDWLTDLPAGRPLLVIAEGLLMYLPVSEVKALLHRLTERFPKGQMIFDVIAPWIARVGSLSGYRMYWGIDDPHQVEKWNPRLSLMDDAPIFCDYAEVPLNRYRVPYHLLSKVTGFRNAFRPLRFTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q747</accession>
    <name>D3Q747_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2641</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017889.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2641"/>
    <dbReference type="EnsemblBacteria" id="ADD42318">
        <property type="protein sequence ID" value="ADD42318"/>
        <property type="gene ID" value="Snas_2641"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2641"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_0_11"/>
    <dbReference type="OMA" id="AYVEDRY"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="220" mass="24013" checksum="94BAC8C0AA666CCD" modified="2010-04-20" version="1">MRVVIVEDDALLRRGLTLLLESEGFEVAASTTTAEEFLEAVDRERPDIAVVDVRLPPTFRDEGLRAAVEARRRHRGLPVLVLSAHVEHDYATQLLSDGDGRVGYLLKERVGKVEEFLDAIRRVVDGGAAIDPEVISQLLAGQKSSGRVLGKLSAREHEVLGLMAEGYGNGSIAATLVITETAVSKHIRNIFAKLDLPQSETGHRRVLAVLAYLQASNRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7F7</accession>
    <name>D3Q7F7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase BadF/BadG/BcrA/BcrD type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017999.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2752"/>
    <dbReference type="EnsemblBacteria" id="ADD42428">
        <property type="protein sequence ID" value="ADD42428"/>
        <property type="gene ID" value="Snas_2752"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2752"/>
    <dbReference type="eggNOG" id="COG2971">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016274_3_0_11"/>
    <dbReference type="OMA" id="PANIMRD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002731">
        <property type="entry name" value="ATPase_BadF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01869">
        <property type="entry name" value="BcrAD_BadFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BcrAD_BadFG" evidence="1">
        <location>
            <begin position="5"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="319" mass="31802" checksum="5F6E5DE4D6FA647F" modified="2010-04-20" version="1">MNVFLGIDAGGSGTTAVAIDLDGQLLGSGRAPAANPQVCSPDQVSSALELAARSALDGTAASVTGGVVGMSGLAATARGEVVKAIASAWDRAGLSCPMRVVGDAVTAFASATSEADGTVIVAGTGAVVAEVRDREITRTVDGLGWLLGDEGSGFWLGLAAARHTARHLSAGRPATRLTDAVTGHLGAHDGEAFVSACYLRPREALAELAPLVCESAADGDADARALAAEAGQRLADSYTTLDPGPGPVVITGGLLTNHTPVRAHLQRALVNRTGTTALIATDAALGGAWLAATRSDGLTAEGAAELHKRLAGDATRGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Y3</accession>
    <name>D3Q7Y3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
            <ecNumber evidence="2">3.5.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.14" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40488">
        <property type="protein sequence ID" value="ADD40488"/>
        <property type="gene ID" value="Snas_0776"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0776"/>
    <dbReference type="eggNOG" id="COG1473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023257_0_1_11"/>
    <dbReference type="OMA" id="RAHACGH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004046">
        <property type="term" value="F:aminoacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="187"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="391" mass="41400" checksum="760FCDE3BF27CAE1" modified="2010-04-20" version="1">MLDGWLTENGSELVQIRRHLHMNPELSGYEHATTALMAEKLAAEGLKPRLIPGGNGLTCDIGEGESGRIVALRGDMDALPIQDPKDVPYRSTVPGACHACGHDVHTTVLLGAGRVLAELDRRGELPGRVRLVFQPSEEKFPSGAPQMMRAGALDGVSSIFAFHCDPRLPTGMVGVRSGPLTAASDMLEVRLTGRGGHTSRPHLTTDLVHALSRVVVDVPALLDRRLDPRTGVALVFGAIEAGSAANAIPREGRVLGTVRMLDRDAWKTVPDMVTQIIEDVVRPTGAEAEITYTRGVPPVINDRVATAMFAGAASAALGESAVVETPVSMGGEDFSWYLEQVPGAMARLGVGRPGEHLDLHQGSFDVDEKAIAHGVRVLVHTALAASASAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q851</accession>
    <name>D3Q851_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tmk</name>
        <name evidence="7" type="ordered locus">Snas_0844</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016127.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0844"/>
    <dbReference type="EnsemblBacteria" id="ADD40556">
        <property type="protein sequence ID" value="ADD40556"/>
        <property type="gene ID" value="Snas_0844"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0844"/>
    <dbReference type="eggNOG" id="COG0125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008049_2_1_11"/>
    <dbReference type="OMA" id="LDRRWTM"/>
    <dbReference type="OrthoDB" id="1585072at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Thymidylate_kin" evidence="6">
        <location>
            <begin position="474"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="671"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="685"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="476"/>
            <end position="483"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="707" mass="74941" checksum="A944C50E2878346D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8C2</accession>
    <name>D3Q8C2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane-flanked domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2820</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018067.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2820"/>
    <dbReference type="EnsemblBacteria" id="ADD42496">
        <property type="protein sequence ID" value="ADD42496"/>
        <property type="gene ID" value="Snas_2820"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2820"/>
    <dbReference type="eggNOG" id="COG3402">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104197_4_0_11"/>
    <dbReference type="OMA" id="MPRWRYR"/>
    <dbReference type="OrthoDB" id="1768296at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="3">
        <location>
            <begin position="84"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="174" mass="19267" checksum="0F07874B7CF6AB77" modified="2010-04-20" version="1">MTQPEHEAPTDRRPARLRPPRHRVEPRAKGLWTVHALLVVLPPVAALAVLAILLPPARGWLTAGLVVVAVLGIGYVLVMPRWRYRVHRWETTEEAVYTASGWLRQEWRVAPMSRIQTIDTSRGPLQRMFRLSSLTITTASAKGAIAINGLDHEIADDLAHQLTAITQATPGDAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8J1</accession>
    <name>D3Q8J1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4792</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020004.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4792"/>
    <dbReference type="EnsemblBacteria" id="ADD44433">
        <property type="protein sequence ID" value="ADD44433"/>
        <property type="gene ID" value="Snas_4792"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4792"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_14_2_11"/>
    <dbReference type="OMA" id="VCTKELC"/>
    <dbReference type="OrthoDB" id="892697at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="3"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="3">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="154" mass="16881" checksum="8F5C94F42772E46D" modified="2010-04-20" version="1">MTVAVGTQAPDFTLKDQNNQEVTLSSFKGHKNVLLVFYPLAFTGVCEGELCGVRDNLSSYQSDEVQVLTVSVDSVFTHKVWADKEGFEFPLLSDFWPHGGVAKTFGVFDEDKGIANRGTFVIDTTGTVRFAEMNLPGEPRDQGAWQKALAELTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8P1</accession>
    <name>D3Q8P1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4842</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020054.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4842"/>
    <dbReference type="EnsemblBacteria" id="ADD44483">
        <property type="protein sequence ID" value="ADD44483"/>
        <property type="gene ID" value="Snas_4842"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4842"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_11"/>
    <dbReference type="OMA" id="HHQQVVP"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="225" mass="25178" checksum="16B9D0A3521AEAEB" modified="2010-04-20" version="1">MRLLIVEDEQRMANALARGLKADGFAVEVAADGEAGLEAARFGSYDAIILDIMLPKLSGYEVIRTLRRENNWVPVLVLSAKDGEYDQSDGLDLGADDYLTKPFSYVVLLARLRALLRRGTPARPSVLTVGDLTLDPARHTVHREDTEISLSTREFSLLEYLMRNAEQVVTKVTLLDHVWSASEDTHVNLVEVYIGYLRKKIDTPFGRSSLQTVRGAGYRLTADRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8T7</accession>
    <name>D3Q8T7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Octanoyltransferase</fullName>
            <ecNumber evidence="6 7">2.3.1.181</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lipoate-protein ligase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoyl/octanoyl transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipB</name>
        <name evidence="12" type="ordered locus">Snas_4888</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>L-lysyl-[protein] + octanoyl-[ACP] = H(+) + holo-[ACP] + N(6)-octanoyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="EC" id="2.3.1.181"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6 7">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the LipB family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="6 7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4888"/>
    <dbReference type="EnsemblBacteria" id="ADD44529">
        <property type="protein sequence ID" value="ADD44529"/>
        <property type="gene ID" value="Snas_4888"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4888"/>
    <dbReference type="eggNOG" id="COG0321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035168_2_1_11"/>
    <dbReference type="OMA" id="GEVTYHC"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16444">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00013">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016262">
        <property type="entry name" value="LPLase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="11">
        <location>
            <begin position="36"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="74"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="146"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="159"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6 8">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="6 10">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR016262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD44529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="213" mass="24149" checksum="346360CD8CD91CBC" modified="2010-04-20" version="1">MSDTRARTLKIDRLGTVDYARAWDLQKDLQDKRINDEIDDTVLLLEHPSVYTAGRRTEKWTYPDDGTPVVEVDRGGQITWHGPGQLVGYPIVKLTKPIDVVKYVRRVEDMLMAVCGEFGVATTRIDDRTGVWIPADDRGPERKIASIGVRVRWAVTLHGFALNCDNDMSFFDHIVPCAIMDKDMTSLSRETGRDVTVDEVIPVTEKHMHLILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q935</accession>
    <name>D3Q935_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016215.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0933"/>
    <dbReference type="EnsemblBacteria" id="ADD40644">
        <property type="protein sequence ID" value="ADD40644"/>
        <property type="gene ID" value="Snas_0933"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0933"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149291_0_0_11"/>
    <dbReference type="OMA" id="MNERARP"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="2"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="147" mass="16406" checksum="119CD9AFC555C889" modified="2010-04-20" version="1">MDDGLADLLHRVVTLLGDAARRRTDDRDGLTYSQIRLLGALEEIEPTTQHRLAQALSVSDPAISRALRPLEADGLVRITVDPAHARRRLVRLNQDGRDAFHAAGKPLYDEFRAALVAAGFPYERYLADTHRLAELLASDETARRKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Y4</accession>
    <name>D3Q9Y4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016267.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0986"/>
    <dbReference type="EnsemblBacteria" id="ADD40696">
        <property type="protein sequence ID" value="ADD40696"/>
        <property type="gene ID" value="Snas_0986"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0986"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036302_1_1_11"/>
    <dbReference type="OMA" id="HMFVMGR"/>
    <dbReference type="OrthoDB" id="311112at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007795">
        <property type="entry name" value="T7SS_EccB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044857">
        <property type="entry name" value="T7SS_EccB_R1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40765">
        <property type="entry name" value="PTHR40765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05108">
        <property type="entry name" value="T7SS_ESX1_EccB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03919">
        <property type="entry name" value="T7SS_EccB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="453" mass="48523" checksum="631347902FF6B466" modified="2010-04-20" version="1">MRTRKELVEAYLFVTRRIISSMMSTNPDALELPMRRSRYSVLGGILLALLIFAGFWVVGMFIPAGKDTWKKEGTIILDTDTGTTYVYMREVLFPVKNMASAKLIAAEEGVTEVGSVDLKGVDRGWELGIQDAPASIPDPQSLVGMPWQVCSARDAYDKTERVSHVVVSASPADAAIGKKALIVTTGKDMYLLWNNMRHHVKDDAALVALGMEPSDAVPVSPVFVSAVNTGPDLVAPKIKKNGKSAGKVDGVKRDYGEFFTVGDQDYVLTPDGFAPVGEVTTALLTEGEAPGPALTPASVIEKFGTTEIEPPGFPQAVPKMESAESDAVVCAVAKDDEKVTLAVHTDPPKAILDPKVFNPVNEYDETDTADHFWLPGGKGALVREVGSPGAQDGTVYLLTDQGAKYALADDAASRLGFREVKPTPVPASLVALVPTGPALDPETVRQQVPFEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA28</accession>
    <name>D3QA28_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sulfurtransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>hydrogen cyanide + thiosulfate = 2 H(+) + sulfite + thiocyanate</text>
            <dbReference type="Rhea" id="RHEA:16881"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:18022"/>
            <dbReference type="ChEBI" id="CHEBI:18407"/>
            <dbReference type="ChEBI" id="CHEBI:33542"/>
            <dbReference type="EC" id="2.8.1.1"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016311.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1030"/>
    <dbReference type="EnsemblBacteria" id="ADD40740">
        <property type="protein sequence ID" value="ADD40740"/>
        <property type="gene ID" value="Snas_1030"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1030"/>
    <dbReference type="eggNOG" id="COG2897">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031618_1_3_11"/>
    <dbReference type="OMA" id="QRPGHVP"/>
    <dbReference type="OrthoDB" id="1385159at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00380">
        <property type="entry name" value="RHODANESE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00683">
        <property type="entry name" value="RHODANESE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="18"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="154"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="283" mass="31544" checksum="1E9A26477DE5D8A1" modified="2010-04-20" version="1">MSRAETLVSADWAEQNLNTDKTVFVEVDEDTTAYDNSHIPGAVKLDWKTDLQDQVRRDFVDRQQFSDLLSQRGIANDDTVILYGGNNNWFAAYAYWYFKLYGHDSVKLLDGGRKKWELDARPLSSDPVNRPATSYVAAEQDRSIRALRDDVLGALGSSNLVDVRSPDEYAGRLLAPAHLPQEQSQRAGHIPTALSVPWSKAANEDGTFKSDKELSELYSEAGVDSSKPTIAYCRIGERSSHTWFVLRELLGHNDVRNYDGSWTEYGSLVGVPIALGDEPGKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA36</accession>
    <name>D3QA36_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016319.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1038"/>
    <dbReference type="EnsemblBacteria" id="ADD40748">
        <property type="protein sequence ID" value="ADD40748"/>
        <property type="gene ID" value="Snas_1038"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1038"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108054_2_1_11"/>
    <dbReference type="OMA" id="RPGANWR"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="3"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="123" mass="14264" checksum="33A02A602B7508CB" modified="2010-04-20" version="1">MLRFTDFIIDCPDPMKLGGFYAELLGLELADDSTDAWANIHCDGFTLAFQRVENYQRPKWPSQEHPQQFHIDFEVDEFEPEQRRAIKLGATLQKNNIGESGYGWQVYIDPAGHPFCLCRNRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA55</accession>
    <name>D3QA55_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcriptional regulator WhiB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">whiB</name>
        <name evidence="13" type="ordered locus">Snas_1057</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">The Fe-S cluster can be nitrosylated by nitric oxide (NO).</text>
    </comment>
    <comment type="PTM">
        <text evidence="11">Upon Fe-S cluster removal intramolecular disulfide bonds are formed.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the WhiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016338.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1057"/>
    <dbReference type="EnsemblBacteria" id="ADD40767">
        <property type="protein sequence ID" value="ADD40767"/>
        <property type="gene ID" value="Snas_1057"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1057"/>
    <dbReference type="eggNOG" id="ENOG5032RUK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106245_2_4_11"/>
    <dbReference type="OMA" id="FAAQRKH"/>
    <dbReference type="OrthoDB" id="1929976at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035731">
        <property type="term" value="F:dinitrosyl-iron complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01479">
        <property type="entry name" value="WhiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034768">
        <property type="entry name" value="4FE4S_WBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003482">
        <property type="entry name" value="Whib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38839">
        <property type="entry name" value="PTHR38839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02467">
        <property type="entry name" value="Whib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51674">
        <property type="entry name" value="4FE4S_WBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="4Fe-4S Wbl-type" evidence="12">
        <location>
            <begin position="12"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD40767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="103" mass="11512" checksum="D191DCE665727404" modified="2010-04-20" version="1">MTMMVDWTSAAACREGDPDALFVQGAEQNVAKKVCKGCRVRMECLADALDNQVEFGVWGGMTERERRALLRKHPDVTSWRKVFEAALEKEAADRIGRVLEPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA59</accession>
    <name>D3QA59_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1061"/>
    <dbReference type="EnsemblBacteria" id="ADD40771">
        <property type="protein sequence ID" value="ADD40771"/>
        <property type="gene ID" value="Snas_1061"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1061"/>
    <dbReference type="eggNOG" id="ENOG5032YI8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183720_1_0_11"/>
    <dbReference type="OMA" id="WEYVTVP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="57" mass="6477" checksum="FEF6C63FE456334D" modified="2010-04-20" version="1">MLHCMQKWEYATVPLLVHATKQILDTWGEDGWELVAVVPGPNAENTVAYLKRPKEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA74</accession>
    <name>D3QA74_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1076</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016357.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1076"/>
    <dbReference type="EnsemblBacteria" id="ADD40786">
        <property type="protein sequence ID" value="ADD40786"/>
        <property type="gene ID" value="Snas_1076"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1076"/>
    <dbReference type="eggNOG" id="COG1510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078983_0_0_11"/>
    <dbReference type="OMA" id="VELHTRW"/>
    <dbReference type="OrthoDB" id="1646730at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_38" evidence="3">
        <location>
            <begin position="5"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="104"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="239" mass="26827" checksum="CA15AB510C70FAD4" modified="2010-04-20" version="1">MPGGRLTPTDRRLIADGLAEGLGYAEIARRLDRPTSTISREVARNGGRDGYRAELAQHDTGRRAHRAAPVPSSPRPRDDGDYRRDPAAVRDFRKRYTAMMADMGLPPITAGVLVSVLITDEPYLTSADLVDQLGISAASVSKAVAYLEPLGLLRRERVPGERRERYLVDESWFQGWSRTVELHTRWASAAGEGAEIFGPRTPAGARLAEMAEFTRFLRDALARELVRWQEMRRRDRSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAA6</accession>
    <name>D3QAA6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018260.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3018"/>
    <dbReference type="EnsemblBacteria" id="ADD42689">
        <property type="protein sequence ID" value="ADD42689"/>
        <property type="gene ID" value="Snas_3018"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3018"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047208_0_0_11"/>
    <dbReference type="OMA" id="LYEFFTP"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="445" mass="46242" checksum="31F93CD95FAE72EB" modified="2010-04-20" version="1">MPDRYRNFANSAVGRQLVRRLGLPRPSPLRRQRPDAPALPGPVLLGGHDVAELEHVLAKRLSAEVHTAETKASAEARYAGLVFDASDLTTIAGLSELYAFFHDRLERLASCGRVLVLGAIPDETGDPEAAATQAALEGFTRSLGKELRAGGTAQLLRLAPGARDGLDATLRFFLSYRSAFVSGQVVTVAATEPGEVPDPARPLDGKVALVTGAARGIGAVTARTLADQGATVVCLDVPEAGEKLATVAGDIGGSALQLNLATDDAPSTLSRWLEERHGGVDIVVHNAGITRDKTLARMDAKRWDSVLGVNLAAPHRVTADLLDRGVLRDGGRVVVLSSVSGIGGNRGQTNYAASKAGLIGLVRALAPGLAERGITANAVAPGFIETRMTAAMPVMEREAGRRLSSLAQGGLPVDVAETIAWLAHPGSAGVTGNVVRVCGQSFLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAF6</accession>
    <name>D3QAF6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Argininosuccinate synthase</fullName>
            <ecNumber evidence="2 9">6.3.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Citrulline--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argG</name>
        <name evidence="10" type="ordered locus">Snas_3068</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10932"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the argininosuccinate synthase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="2 9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018310.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3068"/>
    <dbReference type="EnsemblBacteria" id="ADD42739">
        <property type="protein sequence ID" value="ADD42739"/>
        <property type="gene ID" value="Snas_3068"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3068"/>
    <dbReference type="eggNOG" id="COG0137">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032784_4_2_11"/>
    <dbReference type="OMA" id="QCEVVTF"/>
    <dbReference type="OrthoDB" id="357142at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
        <property type="term" value="F:argininosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01999">
        <property type="entry name" value="Argininosuccinate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00005">
        <property type="entry name" value="Arg_succ_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023434">
        <property type="entry name" value="Arginosuc_synth_type_1_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="PTHR11587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="SSF69864"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00565">
        <property type="entry name" value="ARGININOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="8"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD42739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="402" mass="43734" checksum="04BAD417A80A41CA" modified="2010-04-20" version="1">MTERVVLAFSGGLDTSVAIPYLAEQTGGEVIAVAIDVGQDGEDLNVIRQRALDCGAVEAEVVDAREEFAADYCFPAIQANALYMDRYPLLSGLSRPLIVKHLVDAAIKHGATIVSHGCTGKGNDQVRFEAGLAALAPHLKVIAPARDFAWTRDKAIEYAESKNLPIDVSNKSPYSIDQNLWGRAIETGFLEDIWNAPIEDIYAYTADPSVARDPDEVIITFDAGVPVALDGETKTPLQVITELNSRAGAQGVGRLDMVEDRLVGIKSREVYEAPAAIALITAHQELENVTVERDQARFKKGVDQRWGELVYDGLWFSPLKNSLDAFIGDTQKHVTGDIRLTLHGGRATVTGRRSEASLYDFGLATYDEGDAFDQSLAKGFVDLWSLPSKLASARDERLKGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAK8</accession>
    <name>D3QAK8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018362.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3120"/>
    <dbReference type="EnsemblBacteria" id="ADD42791">
        <property type="protein sequence ID" value="ADD42791"/>
        <property type="gene ID" value="Snas_3120"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3120"/>
    <dbReference type="eggNOG" id="COG4460">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127523_2_1_11"/>
    <dbReference type="OMA" id="DIRPGWQ"/>
    <dbReference type="OrthoDB" id="2062336at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016918">
        <property type="entry name" value="UCP029394"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029394">
        <property type="entry name" value="UCP029394"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="135" mass="14611" checksum="A7BDE9434F4E1B2F" modified="2010-04-20" version="1">MDALDARVAHAVEEMHADLALWLGTEAPPSVYQRIMHAQHPDFSMVGRDGDIVSREELGTELTGAANALPGMTIDIEDLTILASGGDVVVVRFTEIHRHSGTENRRRTTATLTADVSVEEGLRWLAVHETAIATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAR3</accession>
    <name>D3QAR3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020280.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5073"/>
    <dbReference type="EnsemblBacteria" id="ADD44709">
        <property type="protein sequence ID" value="ADD44709"/>
        <property type="gene ID" value="Snas_5073"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5073"/>
    <dbReference type="eggNOG" id="COG5500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111152_2_0_11"/>
    <dbReference type="OMA" id="STFVMRG"/>
    <dbReference type="OrthoDB" id="2075110at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="162" mass="17309" checksum="67088C3977AE38C6" modified="2010-04-20" version="1">MTLAALIFSLLAMMLIGLMTGTFFTWSNAVMPGLNAVKPIEAIAAMRSMNAKILNRVFLAAFTMSGLTALIAAVLLLLDGETDASIAMFVATGVYLAGCFGVTGAVNVPMNKELDAARISDEEWAVMKLWTEFSSKWSRWNAIRGFACAVSLALTGLALYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAY5</accession>
    <name>D3QAY5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="15">2-oxoglutarate dehydrogenase, E1 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Snas_5146</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA = (R)-N(6)-(S(8)-succinyldihydrolipoyl)-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + CoA</text>
            <dbReference type="Rhea" id="RHEA:15213"/>
            <dbReference type="Rhea" id="RHEA-COMP:10581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10582"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="2.3.1.61"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + 2-oxoglutarate + H(+) = (R)-N(6)-(S(8)-succinyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:12188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10483"/>
            <dbReference type="Rhea" id="RHEA-COMP:10484"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="1.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate metabolism; tricarboxylic acid cycle; succinyl-CoA from 2-oxoglutarate (dehydrogenase route): step 1/1.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020352.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5146"/>
    <dbReference type="EnsemblBacteria" id="ADD44781">
        <property type="protein sequence ID" value="ADD44781"/>
        <property type="gene ID" value="Snas_5146"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5146"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0567">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004709_1_0_11"/>
    <dbReference type="OMA" id="RDSYCRT"/>
    <dbReference type="OrthoDB" id="29166at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00997"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="PTHR23152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Transket_pyr" evidence="14">
        <location>
            <begin position="879"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="54"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD44781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1225" mass="134763" checksum="AFC1E64E5F55C18C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB81</accession>
    <name>D3QB81_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplB</name>
        <name evidence="7" type="ordered locus">Snas_1188</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016469.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1188"/>
    <dbReference type="EnsemblBacteria" id="ADD40898">
        <property type="protein sequence ID" value="ADD40898"/>
        <property type="gene ID" value="Snas_1188"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1188"/>
    <dbReference type="eggNOG" id="COG0090">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036235_2_1_11"/>
    <dbReference type="OMA" id="SCIELRP"/>
    <dbReference type="OrthoDB" id="961486at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_L2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="125"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="255"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="279" mass="30664" checksum="51FD24188F0BDDFE" modified="2010-04-20" version="1">MGIRKHKPTTPGRRGSSGADFAEVTRNTPEKSLLRPLTKSGGRNSRGKITTRHRGGGHKRAYRLIDFRRHDKDGIPAKVAHIEYDPNRTARIALLHFADGEKRYILCPKDLVQGARIENGPHADIKPGNNLPLRNIPVGTIVHAVELRPGGGAKLARSAGSGIQLLAREGKYAHLRMPSGEIRLVEVRCRATVGEVGNAEQSNINWGKAGRMRWKGRRPTVRGVVMNPVDHPHGGGEGKTSGGRHPVNPQGKPEGRTRSKGKASDRLIVRRRYANRKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBG6</accession>
    <name>D3QBG6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018419.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3177"/>
    <dbReference type="EnsemblBacteria" id="ADD42848">
        <property type="protein sequence ID" value="ADD42848"/>
        <property type="gene ID" value="Snas_3177"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3177"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060131_7_0_11"/>
    <dbReference type="OMA" id="MWPMWRE"/>
    <dbReference type="OrthoDB" id="1972497at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="113"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="197" mass="21848" checksum="5D2AB819D2B00663" modified="2010-04-20" version="1">MNPPVIRRAKDGEAAALADTVAAAFHDLDVSAWLVPDPGARAEILPRHFRLFTEHALKHGTVHTTDDYSGVAVWLPSSAPDIDDFETRNNPICGDRAPYFNDLGACFDDNHPHHAAHHYLQLLAVLPGAQNQGLGSALMKPQHDHADLTRMPAYLEAASLRCRELYLRHGYEDLGQPIRPRPDAPALYPMWRQPVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBI0</accession>
    <name>D3QBI0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_3192</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018433.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3192"/>
    <dbReference type="EnsemblBacteria" id="ADD42862">
        <property type="protein sequence ID" value="ADD42862"/>
        <property type="gene ID" value="Snas_3192"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3192"/>
    <dbReference type="eggNOG" id="COG0122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2169">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_72_6_11"/>
    <dbReference type="OMA" id="RWPDAFP"/>
    <dbReference type="OrthoDB" id="1781735at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035451">
        <property type="entry name" value="Ada-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004026">
        <property type="entry name" value="Ada_DNA_repair_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010316">
        <property type="entry name" value="AlkA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037046">
        <property type="entry name" value="AlkA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02805">
        <property type="entry name" value="Ada_Zn_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06029">
        <property type="entry name" value="AlkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01009">
        <property type="entry name" value="AlkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57884">
        <property type="entry name" value="SSF57884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="9">
        <location>
            <begin position="87"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD42862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="497" mass="53224" checksum="909F076429AF2606" modified="2010-04-20" version="1">MHEDFERCVRAVQSKDARFDGWFFTAVTSTGIYCRPSCPVVPPKPENMRFYPSSAAAQAAGFRACKRCRPDASPGSPEWNVRADVVARAMRLIADGVVDREGVSGLAARLGYSVRQLERQVRGELGAGPGAVARAQRASTARLLIETTDLAFGQIAFAAGFSSIRAFNDTVVRVFALSPTSLRQRAKSRAVSGGSGALSLRLPFRQPLCPDNVFGHLAATAVPGVEEWRDGAYRRTLRLPHGPGVVSLRPGPDHVGCVLWLSDLRDLSIAIARCRWLLDLDADPVAVDELLSRDEVLAPLVAKAPGRRVPRTVDPGEFAVRAVLGQQVSTAAARTHAARLVARYGQRVEDPGGGLTHLFPSPGELAGLDPDGLAMPVSRKNTLLGLVRALVDGDVELGVGVDWRSAKEALSALPGFGPWTVESIAMRALGDPDAFVASDLGIRLAAEQLGLPTGARALVERSRAWMPWRAYAVQYLWATGEHAINVLPSGDIVSEVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBI8</accession>
    <name>D3QBI8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018441.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3200"/>
    <dbReference type="EnsemblBacteria" id="ADD42870">
        <property type="protein sequence ID" value="ADD42870"/>
        <property type="gene ID" value="Snas_3200"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3200"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="PRHTVYD"/>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="321" mass="33587" checksum="7D1FC371E9C008CB" modified="2010-04-20" version="1">MTGSVVSGRGVAVRYRIGKRVARAVDDVDIDVAGGEVVALAGESGCGKTSLARALLGLEKPSAGVVSWRGVPLRYATKALRPFHADVQFVPQDPAGALNPRHTVYEAVAEGLRIHRRGDEAAKVAEALEWVGLTPAKRFADAYPRQLSGGQKQRVLIAGALVLRPSLVIADEPVASLDASVRGEILALLLRLRDDFGTACLLVTHDLSAAWSISDRTAIMYAGRIVETGATTSVLTAPSHPYTKALLSVLPESGWDAPVVLRGEPPDATAIAPGCRFHPRCPALAEGAAEAVAASCRGKELPVLPASGAHVACYLDDSCPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBK0</accession>
    <name>D3QBK0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3212</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018453.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3212"/>
    <dbReference type="EnsemblBacteria" id="ADD42882">
        <property type="protein sequence ID" value="ADD42882"/>
        <property type="gene ID" value="Snas_3212"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3212"/>
    <dbReference type="eggNOG" id="COG0178">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001370_2_1_11"/>
    <dbReference type="OMA" id="VCFEGTV"/>
    <dbReference type="OrthoDB" id="152379at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="2">
        <location>
            <begin position="479"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="519"/>
            <end position="526"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="790" mass="84191" checksum="38AE99714C9EA6D6" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBL5</accession>
    <name>D3QBL5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42897">
        <property type="protein sequence ID" value="ADD42897"/>
        <property type="gene ID" value="Snas_3227"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3227"/>
    <dbReference type="HOGENOM" id="CLU_2525938_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="84" mass="8879" checksum="D138BD65D64A8CCE" modified="2010-04-20" version="1">MTTHATTPATTTQWQQLCVGLTSLHRASASGHCLACSRALAYPVPHPCPRSRMAAPVVAAIGRDAVFRAFGVADASGRDRHSHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBU5</accession>
    <name>D3QBU5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020405.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5199"/>
    <dbReference type="EnsemblBacteria" id="ADD44834">
        <property type="protein sequence ID" value="ADD44834"/>
        <property type="gene ID" value="Snas_5199"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5199"/>
    <dbReference type="eggNOG" id="ENOG502ZBQ3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088222_0_0_11"/>
    <dbReference type="OMA" id="MIRNAYG"/>
    <dbReference type="OrthoDB" id="1544298at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="239" mass="26106" checksum="A0A00D9B2FC10B7B" modified="2010-04-20" version="1">MDALVDAWEHLFSTAKTIPAWIAIATGVAAVVVVLVSGTWRLSRNVITIAHEGGHAAVAILTGRSLHGIRLHSDTSGLTYTRGSRGGPSAILTLLAGYLTPAVIGLLSAWLIWVGKIVLLLWVMIVLLVAMAIFIRNLYGVFAIVVVGFAMFAIAWWASPEFQSTLAYAGAWFLLFGSVRPVWEIWLQRSRGQQRNSDPDQLAQLTRVPATLWLLLFALFNVGALALGFRLLFPDALTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBW1</accession>
    <name>D3QBW1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5216</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020421.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44850">
        <property type="protein sequence ID" value="ADD44850"/>
        <property type="gene ID" value="Snas_5216"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5216"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_2_3_11"/>
    <dbReference type="OMA" id="DGIGERW"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="7"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="153"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="31254" checksum="F54636A4FAFC4849" modified="2010-04-20" version="1">MPVPAPVAVGFDGSAASQVAVRWATTEARLRQRPLLIVHAFLALAPLRSDSPEAEAAAVRRAVGELLEAEVTRVRELAPDLDVSGVLVNGLTASNTLVDMSRSCELMVVGTRGRNGLTGLLLGSVATQVVEHACCPVLVARPGADEATPPDGRVVVGVDGSTLSHEALRFGFEEASMRGAELLAVHAWRHPASLAGGDLVTLVRDEAELADEKERLLADSLAGWEEKYPDVTVLRQLTHGDPRQVLKDASAGALLLVVGARGLGGFAGLLLGSTSQTLAHHAHSPVAIVHPGRSGYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU20</accession>
    <name>D3PU20_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1256</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016537.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40966">
        <property type="protein sequence ID" value="ADD40966"/>
        <property type="gene ID" value="Snas_1256"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1256"/>
    <dbReference type="HOGENOM" id="CLU_1651092_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="160" mass="16336" checksum="DB566E229BFCCAFE" modified="2010-04-20" version="1">MKTSDTSSEAEGGAADEADSGEAVTEVPTKGRPTAFVLLTCGFLACMCCVGGVFAGGSLGWMRMSNLDDVVTGLGEPDGWSTTDASSTPWRAEASLTGPADAEAVARWLSEVGAETSETKASKCLATKKGCTVELKSGGFPVKVEYGPDGENAEATVLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU36</accession>
    <name>D3PU36_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Geranylgeranyl reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016553.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1273"/>
    <dbReference type="EnsemblBacteria" id="ADD40982">
        <property type="protein sequence ID" value="ADD40982"/>
        <property type="gene ID" value="Snas_1273"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1273"/>
    <dbReference type="eggNOG" id="COG0644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024648_5_2_11"/>
    <dbReference type="OMA" id="LPMAFNR"/>
    <dbReference type="OrthoDB" id="1770293at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011777">
        <property type="entry name" value="Geranylgeranyl_Rdtase_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02032">
        <property type="entry name" value="GG-red-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="40"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="457" mass="49106" checksum="E7B4210266D358AD" modified="2010-04-20" version="1">MHSQALIQPLSSPNATAELKTDNRTARITVPSSNPAPNDADVIVVGAGPAGSASAYYLASHGLDVLLLEKTSFPREKVCGDGLTPKSVKALIRMGIDTSPEAGWTHNKGLRVVAGDTQLSLDWPKLDDYPAYGLTRTRLDFDELLADRAVSAGARLLTEVNVTTPIFDRAGRVCGVEAVVGAEKRPATYTAPIVVSADGVSARMALALGIAKRDDRPLGVAVRRYYKSPAKHDDEYLESWLQLRSAANPNVLLPGYGWIFGLGDGRVNVGLGVLNSSTAFGKTNYRKLLTDWLSSTPEEWGMRDESQADGPIRGAGLPMGFNRVPHYSRGLVLVGDSGGMVNPFNGEGIAYAMESGEIAARFVADALAKPAGPRREAVLRQYPVELKREFGGYYRMGDIFVKLIGNPTVMRLCTEHGLHHPLLMRFVLKLLANLTDARGGDAMDKLINGLSKVAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU60</accession>
    <name>D3PU60_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Erythromycin esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1297</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016577.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1297"/>
    <dbReference type="EnsemblBacteria" id="ADD41006">
        <property type="protein sequence ID" value="ADD41006"/>
        <property type="gene ID" value="Snas_1297"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1297"/>
    <dbReference type="eggNOG" id="COG2312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026490_1_0_11"/>
    <dbReference type="OMA" id="RYGCLTP"/>
    <dbReference type="OrthoDB" id="1068352at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14728">
        <property type="entry name" value="Ere-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007815">
        <property type="entry name" value="Emycin_Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014622">
        <property type="entry name" value="UCP036794_erythomycin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05139">
        <property type="entry name" value="Erythro_esteras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036794">
        <property type="entry name" value="UCP_erythr_ester"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="401" mass="44354" checksum="9E58CA49E459D66C" modified="2010-04-20" version="1">MPTAADVRDSMLSLDGTDDLDPLLRRARSARFVLIGEASHGGHEYYAWRAAITRRLIAEHGFSFVAVEGDGPDCRRVDASVRSDSAADPGDVLEGQRGWPSWLWANEETIEFCRWLRQHNAELPHRQRVGWYGLDAHPLHASIRTVVDYLRDNAPDYVDTALGVHGRGKPLVPAEHLESVTELLTRVHEADAPDDEYAAQDAKLRAGAEGYYNAMLTGGSFGWNTRVAHMVAVLEDLADHHGPNARAVVWAHNTHVGDARATAMAERGEHNLGEFMKDRHGVTDVFTVGFAGGQGEVIAVPVRGEPMRVMPVPPPRPGSLEALLADSGTERGLIFVDEHEWAREKRDQRAIGVVHDDTDDDHWVPTVAAERYNALCWFAATTPVRAVHLDEARRGELPVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU77</accession>
    <name>D3PU77_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP synthase subunit alpha</fullName>
            <ecNumber evidence="10">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">ATP synthase F1 sector subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">F-ATPase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">atpA</name>
        <name evidence="14" type="ordered locus">Snas_1314</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016594.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1314"/>
    <dbReference type="EnsemblBacteria" id="ADD41023">
        <property type="protein sequence ID" value="ADD41023"/>
        <property type="gene ID" value="Snas_1314"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1314"/>
    <dbReference type="eggNOG" id="COG0056">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010091_2_1_11"/>
    <dbReference type="OMA" id="LQAPGVM"/>
    <dbReference type="OrthoDB" id="837522at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1_ATPase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0139">CF(1)</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="13">
        <location>
            <begin position="29"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="11">
        <location>
            <begin position="152"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_C" evidence="12">
        <location>
            <begin position="382"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="172"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Required for activity" evidence="10">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD41023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="545" mass="58863" checksum="287A5DEF72BFFA7F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUG3</accession>
    <name>D3PUG3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018547.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3310"/>
    <dbReference type="MEROPS" id="S12.A11"/>
    <dbReference type="EnsemblBacteria" id="ADD42976">
        <property type="protein sequence ID" value="ADD42976"/>
        <property type="gene ID" value="Snas_3310"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3310"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035614_3_0_11"/>
    <dbReference type="OMA" id="YGYTRRR"/>
    <dbReference type="OrthoDB" id="1439085at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="382" mass="40699" checksum="3AF96B44487DD699" modified="2010-04-20" version="1">MTEVHGTVAEGFEAVREEFAAVAEEAGTQLAAYVHDRRVVDLWTGEDVTGDTLTGIYSSTKGAASLVAALLTQDGVLDLDRPIVDCWPEFGAAGKDRITLRDVLSHRSGIIGVDDGLSADELADDAVIAQRLAAQAPHWRPGMAYGYGGFVTFAVVGEVIRRITGRTLQAHFTERVREPFDLDVYLGLPEDREDRYRTILASLATPEEQAAFWANVPGPNSLLGVAYGLNTDPPLDQVAFANTRRVRERGQASGGGVGSARGLAGMYAAAAFGLHGRDPLLTAATATEFATIHTIGGDLVRGASSAFGLGFEAKGQQYPFLSARAFGHAGSAGSEAFADPITGIAFGYTRRRFSFNWSYPEHDRLVAAVHRAAVSRRTGKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV31</accession>
    <name>D3PV31_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016655.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1377"/>
    <dbReference type="ESTHER" id="stanl-d3pv31">
        <property type="family name" value="Aclacinomycin-methylesterase_RdmC"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41084">
        <property type="protein sequence ID" value="ADD41084"/>
        <property type="gene ID" value="Snas_1377"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1377"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_0_0_11"/>
    <dbReference type="OMA" id="DWETITH"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="27"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="279" mass="29905" checksum="E37575D2CBD8DE69" modified="2010-04-20" version="1">MTERMIDVDGTTLCTESFGDPANPPLLLIAGTGSSMLWWEAELCSTLADEGRFVIRYDHRDTGRSTTSPPGHPDYTGDDMITDAVGVLTAYDIPAAHVVGVSAGGGIAQLLTLDHPERVLSLTLISTTSALSSTHALPGPSEEFIRFVSTATVDWADSASVVEYLVDYCRVLAGETRPFDETPWRNLVQGDVDRAHDIAAIQNHDILQQKSRADQSLSSITAPTLVLHGTADPMFPFPHGEALRAAIPGAELVALRGAGHGVDRADWETITHTVIKHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVA3</accession>
    <name>D3PVA3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016727.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1450"/>
    <dbReference type="EnsemblBacteria" id="ADD41156">
        <property type="protein sequence ID" value="ADD41156"/>
        <property type="gene ID" value="Snas_1450"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1450"/>
    <dbReference type="eggNOG" id="COG1550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149981_1_0_11"/>
    <dbReference type="OMA" id="MYVGALE"/>
    <dbReference type="OrthoDB" id="1813824at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007546">
        <property type="entry name" value="DUF503"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036746">
        <property type="entry name" value="TT1725-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36441">
        <property type="entry name" value="PTHR36441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04456">
        <property type="entry name" value="DUF503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103007">
        <property type="entry name" value="SSF103007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="97" mass="10550" checksum="22B268292010B981" modified="2010-04-20" version="1">MFTGTAVFDILLPGDSRSLKAKRSYVRPIVASLRRLEVSAAEVGATDLHGRTEVGVAVVAGEHAHVQDVLDKCEKLVVGRPEAELLSVRRRIFGPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVE0</accession>
    <name>D3PVE0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016764.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1489"/>
    <dbReference type="EnsemblBacteria" id="ADD41193">
        <property type="protein sequence ID" value="ADD41193"/>
        <property type="gene ID" value="Snas_1489"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1489"/>
    <dbReference type="HOGENOM" id="CLU_1634360_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="162" mass="17323" checksum="5552CFF0D622D792" modified="2010-04-20" version="1">METHTGSADRIAVTAVSPDGSVKAQLADGDVTMNLNRRMLPRHDDFSLARQCGLAASGALAGGERALAMRAARDSDDATSDPEYGRMAERFEDELSHIVTSGRSGPVTVTLRGRTNAEFALRPRTANYLGAEQLARHLAAALAEARQAQVSPVIDICTRVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVG9</accession>
    <name>D3PVG9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3419</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018654.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3419"/>
    <dbReference type="EnsemblBacteria" id="ADD43083">
        <property type="protein sequence ID" value="ADD43083"/>
        <property type="gene ID" value="Snas_3419"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3419"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3899">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006850_4_1_11"/>
    <dbReference type="OMA" id="ERTRLMM"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="846"/>
            <end position="909"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="909" mass="97140" checksum="061F57D579AA2198" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVL4</accession>
    <name>D3PVL4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">H+transporting two-sector ATPase D subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3464</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018699.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3464"/>
    <dbReference type="EnsemblBacteria" id="ADD43128">
        <property type="protein sequence ID" value="ADD43128"/>
        <property type="gene ID" value="Snas_3464"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3464"/>
    <dbReference type="eggNOG" id="COG1394">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1348252_0_0_11"/>
    <dbReference type="OMA" id="WTRAREC"/>
    <dbReference type="OrthoDB" id="2102621at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="22910" checksum="A6FF428866B65E11" modified="2010-04-20" version="1">MIRVPPGRAGRQWLRHRVDTARNAAELLKRKLLILEQRHHHLWTRARECRESWELAARQARQWVDRAVLTGGLRGLRLSAPRESAEVTLTWDTVMGTRYPVATSCAPPRTPPGATVLTGAVWTEANVAHRRALEAAVDCAAAAEALRIVELEIATTRRRVRALDHRWIPGLEATLSELDASLEELERAEHLTRHWASGQDPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVV5</accession>
    <name>D3PVV5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5444</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020647.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5444"/>
    <dbReference type="EnsemblBacteria" id="ADD45076">
        <property type="protein sequence ID" value="ADD45076"/>
        <property type="gene ID" value="Snas_5444"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5444"/>
    <dbReference type="eggNOG" id="COG4198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_679053_0_0_11"/>
    <dbReference type="OMA" id="HPISRAW"/>
    <dbReference type="OrthoDB" id="591335at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008323">
        <property type="entry name" value="UCP033563"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36454">
        <property type="entry name" value="PTHR36454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06245">
        <property type="entry name" value="DUF1015"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="395" mass="42388" checksum="99F0B58F3E8A584B" modified="2010-04-20" version="1">MTAAHPIENAWLSTGGTGAQNYDEYADESRITEIVAAKPTSMLAVEMPDRTPEAVAAGMSFTDCLPAAAERLEALQQTGRFARAGQVVVAYRISGEDRCAYGLFCMVDTDEISTSAEEPGRVIRNEDVFIEKVRQRAALNAQLRHLLSPVLLVQHGKSEELQAALADACVGEPAVTDVDEAGRRHEIWPVAPGPKQDLLCELAGGGDLIVADGNHRSLAAQVGELPRFLAVVTTPESVTIQPYHRLLVSAPLTGEALLDALRERGAEVTAVPGPLSTPDGVVHLYLNETVYAVRLPAVEGSIVERLDHARVESVLFNDILGMDAGDKRITYVGGDYPPSWLAEQVDSGSAVAAILIAAVTVEDFISVNLARLKLPRKSTWFTPKARAGLVLADLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW07</accession>
    <name>D3PW07_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase S1 and S6 chymotrypsin/Hap</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5497</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020699.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5497"/>
    <dbReference type="EnsemblBacteria" id="ADD45128">
        <property type="protein sequence ID" value="ADD45128"/>
        <property type="gene ID" value="Snas_5497"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5497"/>
    <dbReference type="eggNOG" id="COG5640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006842_7_0_11"/>
    <dbReference type="OMA" id="KQGCNVS"/>
    <dbReference type="OrthoDB" id="1468733at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049288" evidence="3">
        <location>
            <begin position="32"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="48"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="272" mass="28130" checksum="B606BA193F8E0A12" modified="2010-04-20" version="1">MRKKTRALIAASAVLAAGTFAIVATTLPAQADDGPSYGEDKGDISTKVVGGEDAPEGAYPWMVRLSMGCGGSMITDQVVLTAAHCVDGTGEDTSVTAYYGANDLNSPDIQERTSAYIHQSETYASDGRGDWALIKLSEPIADAKTIKLATDGTSDEGPNFQLMGWGATSEGGPQADYLQHAEAPYVDDATCQGAYSNLDAEGEICSGLMDEGGIDTCQGDSGGPMVNMAGEEPVQVGIVSWGEGCARPGKPGVYAQVSFWNADINAALGTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW69</accession>
    <name>D3PW69_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016797.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1522"/>
    <dbReference type="EnsemblBacteria" id="ADD41226">
        <property type="protein sequence ID" value="ADD41226"/>
        <property type="gene ID" value="Snas_1522"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1522"/>
    <dbReference type="eggNOG" id="COG2339">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056942_0_0_11"/>
    <dbReference type="OMA" id="WEDINEI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026898">
        <property type="entry name" value="PrsW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36844">
        <property type="entry name" value="PTHR36844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13367">
        <property type="entry name" value="PrsW-protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="374" mass="40754" checksum="E28030173F00BB5C" modified="2010-04-20" version="1">MTGQVLAGRGSGRVFTQPQRPMYWVYVGLFAFGAFKMGTELSRFAELTPTALLISVLANGVLAFVVIKLINWLDLFGRLSVPLMAAAFGWGAVVATTVAAHANDLLTNVLATLGVTDWGIALAAATNEETLKLLGVVAVAVIGRRHIRRPMDGLVLGMMCGLGFEVVENLLYGVQTAITDVNSDISAAIVTNGARLVLGVGGHVMYTGIAGLGVGYFLTRQDRPAATRFAVAVGTFALAWVLHFLWDAPIGDGVSLGALVKYLVQLVAFFLLYRFAARWDWASFTATMSEQPSTVITSDELASMRTLTRRRRARSRARKEAGRAAGKRLRRLQEFQLGYAIALNHSSEPQHDPAVRTRWEDINEIRAEDHHQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWC1</accession>
    <name>D3PWC1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1575"/>
    <dbReference type="EnsemblBacteria" id="ADD41278">
        <property type="protein sequence ID" value="ADD41278"/>
        <property type="gene ID" value="Snas_1575"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1575"/>
    <dbReference type="eggNOG" id="COG5395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078522_1_0_11"/>
    <dbReference type="OMA" id="QIWPGLR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018750">
        <property type="entry name" value="DUF2306_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10067">
        <property type="entry name" value="DUF2306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="308" mass="34348" checksum="CFA9757BDEEB53DE" modified="2010-04-20" version="1">MTTTTNTPAAVAKPPRIRWWKRPWVVPLFFIATVFLAFSVPRYLTFDPANSFIDIPDWFPPYYALLVTHVVFAAVAMVTCCMQIWPWLRARKPKWHRISGRVYVFVGVLPAGLSALVIGAITPFGPVAAASSLIMAPLWLVFTFTGYRMARQRRFVEHRRWMIRSFALTMSIVLNRFLGAAATITLLRYKDSDFHGDDKIVTYLAAGMTTWLGWTICLLIAEWWLERGTAAQRRARKAKRANQTQPPRHQATRPAAEPQPGPAPTAPLTEAPPRVPPPQAAPLPPAAEPPRVPPPPAAPAPYGSGPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWV6</accession>
    <name>D3PWV6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5549</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020751.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5549"/>
    <dbReference type="EnsemblBacteria" id="ADD45180">
        <property type="protein sequence ID" value="ADD45180"/>
        <property type="gene ID" value="Snas_5549"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5549"/>
    <dbReference type="HOGENOM" id="CLU_717483_0_0_11"/>
    <dbReference type="OMA" id="GETSAMR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="357"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="385" mass="41989" checksum="B682D9C4084E2CEF" modified="2010-04-20" version="1">MSHNAFDQYGEPPWRGAPVSPAPQHGRRRNPYAPDGQADSGRQGPPRQRLMMDEPPSVEAPTLWPPVPEPSPPRMGAGLRPYAEPSTEEAPALRPQSRFREPSTSENLTVGQRPPSPYREYATGETATVRPHSAPPSQRHPSPPQSAPPYQRQQGFDAPQRPASAPPYQRQPGFDEPPTSFPPASAPPFQHHAPEPTARIERQSFREPPTGETSAMRPNSAPPFRQDSPPQRPYSAPPMPQSYAGDTATIDRQPFHEPPTAQATTVQPHSAPPLRHDSPPQRPHSAPPMQRPHAADTAIIDRQPPQFGYESPQSTIQVEPDTGSLTTSQLAPAPADPPWQSRRAAEEDASYISPVRVLGTVGVIVIVIAIAGALIWGLNLYGDQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWY4</accession>
    <name>D3PWY4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Multicopper oxidase type 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5577</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020779.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5577"/>
    <dbReference type="EnsemblBacteria" id="ADD45208">
        <property type="protein sequence ID" value="ADD45208"/>
        <property type="gene ID" value="Snas_5577"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5577"/>
    <dbReference type="eggNOG" id="COG2132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009100_6_0_11"/>
    <dbReference type="OMA" id="WNQMRMS"/>
    <dbReference type="OrthoDB" id="971126at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13896">
        <property type="entry name" value="CuRO_3_CopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034279">
        <property type="entry name" value="CuRO_3_CopA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048045" evidence="4">
        <location>
            <begin position="30"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="68"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="247"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="384"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="199"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="498" mass="53722" checksum="2C20FE56CA159EF9" modified="2010-04-20" version="1">MSPVSRRSVLRAGVAASGAAILTGCASESADSYVSPDGDRVAEAEAARDPGKVRKFTLKPGRTEVDLGGVAVTTWAYGGKIPGEPIRVTRGEQIKAVLDNGLPDPTTVHWHGLALRCDADGVPDVTQKPVGAGERHTYTFTAAHAGTYWFHPHVGVQQDRGLYAPLIVEDPDEPLSYDEEWIVVLDDWMDGVTGSPDDVLKELGGGMSHGGHSGGDSDDEPQSQGHMLMGADSDLLGGDAGDVSYPHFLINGRVPADPEVFKVKPGTRLRLRVINAAGDTAFRLALGGHTMTVTHTDGFGVRHTETDALLLGMGERYDVLVELGDGVFPLVALAEGKQELARAIVRTASGETPAADVRPTELDGTIAGYSDLEPDDSVRLKRRDPDETIDLDLTGGMMKYDWGINGESFDPDRLYGITEGDRVRLRFKNTTTMWHPMHLHGHTFALSGTGLRKDTAIVLPGQTLKVDFDADNPGRWMIHCHNVYHSESGMMTLLGYRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX34</accession>
    <name>D3PX34_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020829.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5628"/>
    <dbReference type="EnsemblBacteria" id="ADD45258">
        <property type="protein sequence ID" value="ADD45258"/>
        <property type="gene ID" value="Snas_5628"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5628"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083019_0_0_11"/>
    <dbReference type="OMA" id="EPMGVHR"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="149"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="288" mass="31421" checksum="889EDD741AF98E4E" modified="2010-04-20" version="1">MTIELAQPRVDQLSEATSALRSWQHEGAPMQLHPGDIGWYWRFGTETTAAAVRTWSRDGRILAVGLLDGSDLLRITMAPDSRRDEELSHQLTQDLTDPKRGVLPEGKVYVEAPQDALIQELLHETGWATDEPWTPLRLDLTEPVKDPGIRYEVAGPDKAHVAAEVVRASFDKSTFTEDRWQAMASGVPFADARCLVAYDENDNAVATVTVWSAGPGKPGLIEPMGVHRDHRGHGHGKAMNIAAAAVLRELGSSSVLVCTPSSNVGAVATYKSAGFQARPEVLDRRRDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXA7</accession>
    <name>D3PXA7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell wall hydrolase/autolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1668</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016941.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1668"/>
    <dbReference type="EnsemblBacteria" id="ADD41370">
        <property type="protein sequence ID" value="ADD41370"/>
        <property type="gene ID" value="Snas_1668"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1668"/>
    <dbReference type="eggNOG" id="COG0860">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014322_9_5_11"/>
    <dbReference type="OrthoDB" id="1184688at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048050" evidence="1">
        <location>
            <begin position="32"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="MurNAc-LAA" evidence="2">
        <location>
            <begin position="96"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="213" mass="22331" checksum="FA1921D31388FCA5" modified="2010-04-20" version="1">MPKTIMTRRNVLLAGITGLVAAPLVGGIAMADAAAKVYIDPGHGGSDSGAVGHGLQEKALTLDISLRLRDLLNANGNVEVRMSRDTDIDRSLSYRTSDANSWGAGFFISVHINSGGGTGFESYRYTGTTGDTQRAQETIHPAVYGAMTGVGQTPDRGIKTANFHVLRETAMPAVLTENLFIDRAEDAALLGNADFIAAVAQGHANGILSYLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXE0</accession>
    <name>D3PXE0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CMP/dCMP deaminase zinc-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016974.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1704"/>
    <dbReference type="EnsemblBacteria" id="ADD41403">
        <property type="protein sequence ID" value="ADD41403"/>
        <property type="gene ID" value="Snas_1704"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1704"/>
    <dbReference type="eggNOG" id="COG0590">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025810_5_1_11"/>
    <dbReference type="OMA" id="GDHPENP"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="163" mass="17601" checksum="8DF2AA6BE7EB59B2" modified="2010-04-20" version="1">MSVGSLTETDRQHLRRCVDLAREALDAGDDPFGSLLVDGAGVVRREERNRERSVDATCHPEFALAKWAGANLSPDERRDSVVYTSGEHCPMCSAAHAWVGLGRIVYVASSAQLTAWRREQGFGPGPVASLSIRDVAPAIPVAGPEPSLQEEIFALHRRAAARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXI5</accession>
    <name>D3PXI5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3657</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018886.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3657"/>
    <dbReference type="EnsemblBacteria" id="ADD43315">
        <property type="protein sequence ID" value="ADD43315"/>
        <property type="gene ID" value="Snas_3657"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3657"/>
    <dbReference type="eggNOG" id="ENOG502ZZP3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114557_0_0_11"/>
    <dbReference type="OMA" id="MGFVFLW"/>
    <dbReference type="OrthoDB" id="1853589at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="184" mass="19955" checksum="B5FDD83E1D587019" modified="2010-04-20" version="1">MSTSTRHVTHTGPCLPIDDTDPRQHHGRRVWALARIGVGWIFLWAFLDKTFGLGYATPPDHSWLNGGRPTQGFLANSASGPFKGIYTSIAGAAWADWLFMLGLAGIGIAMILGIGMRIAAIAAAIQLVLMWSVALPPANNPLIDDHIIMAILVIGLAYANAGDTWGLGRKWSQSQAVNRWPFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYF7</accession>
    <name>D3PYF7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1828"/>
    <dbReference type="EnsemblBacteria" id="ADD41524">
        <property type="protein sequence ID" value="ADD41524"/>
        <property type="gene ID" value="Snas_1828"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1828"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_3_1_11"/>
    <dbReference type="OMA" id="WSRFTGY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049560" evidence="1">
        <location>
            <begin position="25"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="455" mass="50610" checksum="E7264FEBD52300A9" modified="2010-04-20" version="1">MRRARALLAPALIAALLGGMTACAGEEKDPGEIDVWIGFVDHRLDWMKDRAKEFEDEHPGYKVNITPYKDYPTLWDKLTAAAEQGEPPTIAQNFEAATQESRDAVNSEGEPLFASVEKEIDGRKEILGEKVVLDDVIDATRNYYTLDGEFASMPWNTSTPVFYSNTDILKKAKIKEAPKTWEDLQAACDKIDKMKDGPKNCITWPNQAWFLEQPLAEQGGLLVNKDNGRSGRATKIDLTSDKFLAWAKVWADMSKKKQYSYSGKQEDWITPTKNFTGQEVAFMMTSSAEASVVAKQAKESDFGFEVTKMPLKKGAPYSGNFIGGATLWMTAGLEKKTSDGALAFMQYINNPENAADWHKITGYVPVTKSAEELLEKEKWFDDNPHHKVAIEQLAATDGSPAATGPIVGNFVAIRKEMQQAMEDIMNNGDDPAERFKEAEKACQKLLDDYNELSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYG4</accession>
    <name>D3PYG4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1835"/>
    <dbReference type="EnsemblBacteria" id="ADD41531">
        <property type="protein sequence ID" value="ADD41531"/>
        <property type="gene ID" value="Snas_1835"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1835"/>
    <dbReference type="HOGENOM" id="CLU_2208431_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="107" mass="11764" checksum="8C46536A0152F05F" modified="2010-04-20" version="1">MDADCPGIQPDTAARLVTLRERLRGFRAELQEGNVSPELWSGVVECGVEATSLRESAMNQLNREPDSEHTRRGAGYAISIETDIWSFANAIAGLCLKQAEARRDTDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYG6</accession>
    <name>D3PYG6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP synthase epsilon chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP synthase F1 sector epsilon subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">F-ATPase epsilon subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">atpC</name>
        <name evidence="10" type="ordered locus">Snas_1837</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 8">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cell membrane</location>
            <topology evidence="1 7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017104.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1837"/>
    <dbReference type="EnsemblBacteria" id="ADD41533">
        <property type="protein sequence ID" value="ADD41533"/>
        <property type="gene ID" value="Snas_1837"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1837"/>
    <dbReference type="eggNOG" id="COG0355">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084338_4_0_11"/>
    <dbReference type="OMA" id="AADHFVW"/>
    <dbReference type="OrthoDB" id="1696893at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="PTHR13822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="SSF51344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01216">
        <property type="entry name" value="ATP_synt_epsi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7 8" id="KW-0139">CF(1)</keyword>
    <keyword evidence="7" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 7 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_DE_N" evidence="9">
        <location>
            <begin position="5"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD41533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="93" mass="9603" checksum="1E4101D34CE28781" modified="2010-04-20" version="1">MAKTLTVELVAVEEKVWTGQATMLIARTTEGELGVMPGHAPLLGQLADPGTVRIKTESGEEIAYQVNGGFLSVTGTGATVLAETCEPAQTTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYJ1</accession>
    <name>D3PYJ1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tryptophan 2,3-dioxygenase</fullName>
            <shortName evidence="1">TDO</shortName>
            <ecNumber evidence="1">1.13.11.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Tryptamin 2,3-dioxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Tryptophan oxygenase</fullName>
            <shortName evidence="1">TO</shortName>
            <shortName evidence="1">TRPO</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Tryptophan pyrrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Tryptophanase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">kynA</name>
        <name evidence="2" type="ordered locus">Snas_1862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-tryptophan + O2 = N-formyl-L-kynurenine</text>
            <dbReference type="Rhea" id="RHEA:24536"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58629"/>
            <dbReference type="EC" id="1.13.11.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="1">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tryptophan 2,3-dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.11" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017129.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1862"/>
    <dbReference type="EnsemblBacteria" id="ADD41558">
        <property type="protein sequence ID" value="ADD41558"/>
        <property type="gene ID" value="Snas_1862"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1862"/>
    <dbReference type="eggNOG" id="COG3483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063240_0_0_11"/>
    <dbReference type="OMA" id="MLFIVVH"/>
    <dbReference type="OrthoDB" id="1660023at2"/>
    <dbReference type="UniPathway" id="UPA00333">
        <property type="reaction ID" value="UER00453"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004833">
        <property type="term" value="F:tryptophan 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01972">
        <property type="entry name" value="T23O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004981">
        <property type="entry name" value="Trp_2_3_dOase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10138">
        <property type="entry name" value="PTHR10138"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03301">
        <property type="entry name" value="Trp_dioxygenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="SSF140959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0823">Tryptophan catabolism</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="45"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="264" mass="30512" checksum="9D6DB783F7962159" modified="2010-04-20" version="1">MANDLDPRFGEQGGKLTYGSYLRIPELLAQQHPASNPEAHDELLFITIHQVYELWFKLLLHELDDARDRMLDGESYRPRVRLDRCHTILKVLIEQVDVIDTMTPQDFLEFRNRLAPASGFQSVQFRELEFLSGLKDPGYLERFRGLSEDESQRLRRRLTEPSLWDGYLAAVRHAGFATETRDERVAALREIAADRQSYGQLWDLAESLVDHDQALSLWRARHVLMAERQIGTKPGTGGSAGGTYLRSRVELRCFPELWELRSLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYP1</accession>
    <name>D3PYP1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019045.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3818"/>
    <dbReference type="EnsemblBacteria" id="ADD43474">
        <property type="protein sequence ID" value="ADD43474"/>
        <property type="gene ID" value="Snas_3818"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3818"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_5_0_11"/>
    <dbReference type="OMA" id="GAWGTNC"/>
    <dbReference type="OrthoDB" id="1581636at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="12"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="231" mass="24265" checksum="0FFF2AEF4472A985" modified="2010-04-20" version="1">MLIESVVAEAFATNCYVVATGAGSECVVIDPGIGIASRLEKLLADKRLRPVAVMLTHGHFDHTFSVVPVCGARGISAYVHPGDRGQLVDPFSGLPPQFKAMAGGLEWAEPDDVEELPQTGPLNLAGIDFTVDHAPGHTPGSVLFRASDDEADYCLSGDVLFAGSIGRTDFPGGDNAAMERSLADKILPLDDATVVLPGHGPATTIGAERRGNPFLRRIVDSGHMEAPTRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYQ3</accession>
    <name>D3PYQ3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bcr/CflA family efflux transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_3830</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Bcr/CmlA family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3830"/>
    <dbReference type="EnsemblBacteria" id="ADD43486">
        <property type="protein sequence ID" value="ADD43486"/>
        <property type="gene ID" value="Snas_3830"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3830"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_47_0_11"/>
    <dbReference type="OMA" id="YFFMLNI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004812">
        <property type="entry name" value="Efflux_drug-R_Bcr/CmlA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00710">
        <property type="entry name" value="efflux_Bcr_CflA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="9">
        <location>
            <begin position="19"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="413" mass="42660" checksum="368CFD00185FD087" modified="2010-04-20" version="1">MSAAEAAPQSAGHPRRFVALLVLTLGVITATGPLATDLYLPAFPEIAKDLDAPQSHIQLTLTSAMFGLAVGQMIIGPMSDAFGRRRPLLIGTAIFTVASFLCVFVPSAGVFIALRFVQGAAGAAGAVIARAIVRDHFSGDAITKFFSRLVLVTMLAPMLGPILGAQLLRVGPWQVGFIVLTVVSIIGMVLVYFALPESLPASQRRATTPAALLNVVRRLIADPRFIGPALTLALVFGGLFTYISSFSFVAQEQLGATAQQYSYVFGINTLAMLGGTQINGFLIGRVGTRSRLIAGLAGSCVGVLALAILDVSGATDLVSLTIALAILMLSLGMVFPNCTSLALASQPASVAGTGSALIGTLQFGLGGAIPAAAAWTPDGRVSLASMVIVMLSAILVAVPVFALFGVRATRYAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYR2</accession>
    <name>D3PYR2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">YidE/YbjL duplication</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_3839</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AAE transporter (TC 2.A.81) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019066.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3839"/>
    <dbReference type="EnsemblBacteria" id="ADD43495">
        <property type="protein sequence ID" value="ADD43495"/>
        <property type="gene ID" value="Snas_3839"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3839"/>
    <dbReference type="eggNOG" id="COG0490">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2985">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035023_2_2_11"/>
    <dbReference type="OMA" id="GPQFFAN"/>
    <dbReference type="OrthoDB" id="1458740at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022457">
        <property type="entry name" value="Asp_Ala_antiprt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006512">
        <property type="entry name" value="YidE_YbjL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06826">
        <property type="entry name" value="Asp-Al_Ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03802">
        <property type="entry name" value="Asp_Ala_antiprt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01625">
        <property type="entry name" value="YidE_YbjL_dupl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="448"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="472"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="538"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="9">
        <location>
            <begin position="202"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="562" mass="58451" checksum="E7EC36D7961A2E04" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ84</accession>
    <name>D3PZ84_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5885"/>
    <dbReference type="EnsemblBacteria" id="ADD45513">
        <property type="protein sequence ID" value="ADD45513"/>
        <property type="gene ID" value="Snas_5885"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5885"/>
    <dbReference type="eggNOG" id="ENOG50321E0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_754115_0_0_11"/>
    <dbReference type="OMA" id="CAHTSAM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="329" mass="35956" checksum="6A8121516C3CC183" modified="2010-04-20" version="1">METLCHRYAFGDVRELLPMLRLPESELNRLRRICLFGQRLLDLDAEDFDMADAEAGGPEYTALVDRARACRMPQEPREVNRGALSSLRPAYDLLLEVVRARHLRNEMASLVATVHIIAEYLPLLVWEAVWGHAADPMRIDDNVDGADSVFGQQDVTCGHNRTDKGATARILRIDKAPGQGWRTYLDRQHSNVAHALGVCAAECRDKCSVVTRLPAAVQGQLAERCVVALAFGDSGVIKLRHAAPVGHGFGVPSVEELDETWQHTREVLGKRGGLAESILADDGFCLPGLPSLLTALAGTAIVPDTLLRDTAALTVTKLHNATVHLREAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZA8</accession>
    <name>D3PZA8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_1886</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017153.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1886"/>
    <dbReference type="EnsemblBacteria" id="ADD41582">
        <property type="protein sequence ID" value="ADD41582"/>
        <property type="gene ID" value="Snas_1886"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1886"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012341_1_0_11"/>
    <dbReference type="OMA" id="LNIMYGL"/>
    <dbReference type="OrthoDB" id="856767at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048122" evidence="7">
        <location>
            <begin position="25"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="693"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="746"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="787"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="277"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="723"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD41582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="821" mass="84463" checksum="EFC16D00C6A357E2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZE2</accession>
    <name>D3PZE2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017187.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41616">
        <property type="protein sequence ID" value="ADD41616"/>
        <property type="gene ID" value="Snas_1920"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1920"/>
    <dbReference type="eggNOG" id="ENOG5033P7G">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_808066_0_0_11"/>
    <dbReference type="OMA" id="RIRFWAG"/>
    <dbReference type="OrthoDB" id="2197510at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="330" mass="34804" checksum="B0BCF9E0D8DBD6D5" modified="2010-04-20" version="1">MIPRIRFWAGLVCAMAAAIWWALGITVIQPMIEPLQTAENNTYWLRDVRWLALLVIVLAFVWSFRGDKRLSAMAAGALVVGIAVDILLDRFDDDFMTRNFDFVESSSIRWGAYLVVILVPGAWIRAKFQPNRPSPRVSMMAAMVAAVAAGFASALESPTDREWYLAASALVLVALLTAIGVGAAHSAANRWGRYEWGLAGLAALAIVGLTVIGRLGDPPAATALFSTLALLGTAAGAMALLATAGRWQLAPRLVIAVCLGALAVLVSVVAMIVMVATGVASVFTALAGNPAVNAADWDTVMTLPAVAAGLFLGWGLVSYDRKAMTAPGPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZJ1</accession>
    <name>D3PZJ1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">5-carboxymethyl-2-hydroxymuconateDelta-isomerase</fullName>
            <ecNumber evidence="3">5.3.3.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1969</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.3.3.10" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1969"/>
    <dbReference type="EnsemblBacteria" id="ADD41665">
        <property type="protein sequence ID" value="ADD41665"/>
        <property type="gene ID" value="Snas_1969"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1969"/>
    <dbReference type="eggNOG" id="COG0179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028458_4_2_11"/>
    <dbReference type="OMA" id="YALSIDM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008704">
        <property type="term" value="F:5-carboxymethyl-2-hydroxymuconate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018833">
        <property type="entry name" value="DUF2437"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10370">
        <property type="entry name" value="DUF2437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2437" evidence="2">
        <location>
            <begin position="5"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="62"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="262" mass="27721" checksum="9D7D0F6FAC68C081" modified="2010-04-20" version="1">MTAVRIARIAHARGMSFATVEGEGPGATVAEIDGLPFGDLSLTGQRWALEDVRLMAPILPSKVVCVGRNYAAHAAEQSAPVPTEPLLFLKPSTSVIGPGDAIRLPPQSQQVDHEAELAIVIGIPGARRVTTPAEAAAAIFGYTCANDVTARDLQKSDSQWTRAKGFDSFCPLGPWIETELDVSDVEVRCEVNDSVRQLGRTKDMTFSPATIVSYVSHVMTLLPGDVILTGTPEGIEPMVAGDSVTVSIEGIGTLTNTVVNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZR4</accession>
    <name>D3PZR4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cobalamin B12-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3949"/>
    <dbReference type="EnsemblBacteria" id="ADD43601">
        <property type="protein sequence ID" value="ADD43601"/>
        <property type="gene ID" value="Snas_3949"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3949"/>
    <dbReference type="eggNOG" id="COG2185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065773_0_0_11"/>
    <dbReference type="OMA" id="AIMNMKG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028991">
        <property type="entry name" value="KamE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036843">
        <property type="entry name" value="KamE_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16554">
        <property type="entry name" value="OAM_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117778">
        <property type="entry name" value="SSF117778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="1">
        <location>
            <begin position="103"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="248" mass="26957" checksum="79E7DF853256C76A" modified="2010-04-20" version="1">MSNIVRPYGDTTGDGMVQMSFTLPVKHDKRAEGAAAQLASKMGMDPAMVVHAQQMGDSHTFFVVYGKVSHLVNLEDVNVVERDYPLLGAKEVNAIVKERLGRKLVVVGACIGTDAHTVGIDAILNIKGFAGEKGLEYYRELRVLNLGAQVAVPDLVNRAVDEEADAVLVSQVVTQRDAHLHNTRELSAAFREALPPEKRPLLIIGGPRFDETMADELGVDRIFSRGTTPADVASYITHKLITSKELVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q064</accession>
    <name>D3Q064_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein translocase subunit SecE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">secE</name>
        <name evidence="9" type="ordered locus">Snas_5966</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021164.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5966"/>
    <dbReference type="EnsemblBacteria" id="ADD45593">
        <property type="protein sequence ID" value="ADD45593"/>
        <property type="gene ID" value="Snas_5966"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5966"/>
    <dbReference type="eggNOG" id="COG0690">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113663_1_2_11"/>
    <dbReference type="OMA" id="PNRKQMI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005807">
        <property type="entry name" value="SecE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038379">
        <property type="entry name" value="SecE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33910">
        <property type="entry name" value="PTHR33910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00964">
        <property type="entry name" value="secE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="147" mass="16400" checksum="7FF0820BD3972501" modified="2010-04-20" version="1">MADDDSRSEDAEKRPGKSSKPSKRPSKSEDAKAKAGKKSDKKSDKADDDAKPDKVEKSEKGKAVKTAAKSEAKDDKPKKKPGLLRRFGIFIREIFEQLRKVVYPTRKQLLTYTAVVLVFVTIMIGVIYGLDYVMSKGVMWVFGGNDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0M1</accession>
    <name>D3Q0M1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017328.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2063"/>
    <dbReference type="EnsemblBacteria" id="ADD41757">
        <property type="protein sequence ID" value="ADD41757"/>
        <property type="gene ID" value="Snas_2063"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2063"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_7_4_11"/>
    <dbReference type="OrthoDB" id="1865374at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="20"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="188" mass="20489" checksum="2C11F696E1C5E5B1" modified="2010-04-20" version="1">MSWQSNRKRRLLADLAGTVLEIGAGRGANFGYLPSGVRWLGLEPHRRRRASLIAAASRHGRGAEVLAAPAEAIPLPDASCDAVVSTIVLCSVRDQDAALAEVRRVLRPGGRFVFLEHVAAPRGTWTRRLQRCWAPVSRRVDSGCDPARDTAAAIERSGFAWRELELFEQPFAFGLSVPFIAGRAFTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Y2</accession>
    <name>D3Q0Y2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate kinase FGGY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019303.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4080"/>
    <dbReference type="EnsemblBacteria" id="ADD43732">
        <property type="protein sequence ID" value="ADD43732"/>
        <property type="gene ID" value="Snas_4080"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4080"/>
    <dbReference type="eggNOG" id="COG1070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009281_3_3_11"/>
    <dbReference type="OMA" id="FLHQADW"/>
    <dbReference type="OrthoDB" id="1619686at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="1">
        <location>
            <begin position="12"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="2">
        <location>
            <begin position="264"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="536" mass="55660" checksum="C56D1C126274E101" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q130</accession>
    <name>D3Q130_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_4129</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019351.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4129"/>
    <dbReference type="EnsemblBacteria" id="ADD43780">
        <property type="protein sequence ID" value="ADD43780"/>
        <property type="gene ID" value="Snas_4129"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4129"/>
    <dbReference type="eggNOG" id="COG1104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_0_0_11"/>
    <dbReference type="OMA" id="CLQSANH"/>
    <dbReference type="OrthoDB" id="839689at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="8">
        <location>
            <begin position="5"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD43780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="376" mass="39630" checksum="BA88374024CE9ACF" modified="2010-04-20" version="1">MTFTYLDAATASPVHPVAEQAFQAASADGWADPSRLYSRARRARQLLDAARETVAEAIGARPDEVSFTASGTQAVHAGVLGALAAGHRRGDRLVHSAVEHSSVLHAAGWHTDRGGASMQVPVARTGAIKLDALAEAVGQPGVALVAVQSANHEVGTVQPLTEVAELCGDIPLLVDAAQSLGRMPVPAWSLLCGSARKWGGPAGVGVLAVRAGVRWRSPWPEDSHDPDAPGALNLPAVVAAAASLRAVLTEREKEDERLRSLTSLIRAEVARIPYVEVVGDPVERLPHIVTFSYPFEDGQPLLVELDRRGFAVSAGSSCTSSTLSPSHVLENMGVLSHGNIRVSLHRETTADDVDRFLTALPQVVAKVRDESGVSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1X3</accession>
    <name>D3Q1X3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphotransferase system, phosphocarrier protein HPr</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017411.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2146"/>
    <dbReference type="EnsemblBacteria" id="ADD41840">
        <property type="protein sequence ID" value="ADD41840"/>
        <property type="gene ID" value="Snas_2146"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2146"/>
    <dbReference type="eggNOG" id="COG1925">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136230_3_2_11"/>
    <dbReference type="OMA" id="APHGIHT"/>
    <dbReference type="OrthoDB" id="404807at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPr" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="94" mass="9565" checksum="2E0B49FB63A4754F" modified="2010-04-20" version="1">MATRTVTIGSSSGLHARPAKLFVEAASEQPVEVRISTAAKAAVPARSLLAVMALGAHQGTEVTLEADDGPEADSALDTLAALLARDLDAEPDNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1Z8</accession>
    <name>D3Q1Z8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2173</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2173"/>
    <dbReference type="EnsemblBacteria" id="ADD41865">
        <property type="protein sequence ID" value="ADD41865"/>
        <property type="gene ID" value="Snas_2173"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2173"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="375"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="420"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="449"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="20"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="477" mass="49128" checksum="73F58F860BD2FAC1" modified="2010-04-20" version="1">MTGTTVHKPETTSGLRRRLVLAALLSGTFMLLLDTTIVNLALPPITADLGAGESALQWIVSGYALAYGLFLLPAGWLGDRIGHKSVLILGLSVFTVASLLCGVANGSGELIAWRVVQGVAAGAVNPSILAFIRLLYSNSERGRAFAAYGTVAGAATSLGPILGGLLIDWDVAGLSWRPIFLANLPVGIAAVAAVALLAPRTETTARRFDVPGLLLVTAAMFALTFPLTQGREIGWPVWTFVTLAAAPVLLLVFTRWQLFLIRRGRDPLVDVRLFARRSFAAGVGLIMAFFAGFIALMFAVSLYLQLGIGFSTLEAGLTMMPFAIGTGLGSVLGNTVIAPRLGRGVLHLGTAIVCVGIGGLEAVLGFATVPPNAGWLLGPFLVAGIGCGMIIGPNANIVLSDVPNNVAGIASGTLSTSQRLGTALGVAAIGVVLFTSLDGSTAPGDYTHATMIAVACSLGAMVLTGILAFLLPGRKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q257</accession>
    <name>D3Q257_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017495.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2234"/>
    <dbReference type="EnsemblBacteria" id="ADD41924">
        <property type="protein sequence ID" value="ADD41924"/>
        <property type="gene ID" value="Snas_2234"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2234"/>
    <dbReference type="eggNOG" id="ENOG5033408">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098258_1_1_11"/>
    <dbReference type="OMA" id="QERTPRW"/>
    <dbReference type="OrthoDB" id="1911879at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021215">
        <property type="entry name" value="DUF2752"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10825">
        <property type="entry name" value="DUF2752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="23981" checksum="4C9FBE62776E2091" modified="2010-04-20" version="1">MSDPLGSAPTQEFPRIHEDASETREIPYVTPSGTGTGDTSQATQQLPYVTPQPATAGPGHTPLPSQGWTRPVRRGKAATFFAKIRNAPAWVAPAALLTCFAGAAAVVVTTDPTDDVGTTTCAFKLVTGFDCPGCGGTRAFFYLLNGNIPEAARNHAIALFAAPFLVWMYLTWAGRRMFPKLRDKLPQFRITAAHATMFLIAWAVFWMVRNLPFAPFTSLYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q295</accession>
    <name>D3Q295_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019399.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4178"/>
    <dbReference type="EnsemblBacteria" id="ADD43828">
        <property type="protein sequence ID" value="ADD43828"/>
        <property type="gene ID" value="Snas_4178"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4178"/>
    <dbReference type="eggNOG" id="ENOG5033294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051322_0_0_11"/>
    <dbReference type="OMA" id="AIECEAR"/>
    <dbReference type="OrthoDB" id="1650329at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="315" mass="35336" checksum="EA912E4ACE93F9F6" modified="2010-04-20" version="1">MTLTQELIEELRLLHRGRGVAAAELGSRLGPRLLSLTELGSDADTSRLRAELMERLRLCVARLGDAELRLAAEADLGLRHSHLELAERRARLVIDLRWSERTVYRRVDEARCLLAEVIATELSGRGDSAEGWYLASFDALMRLDRDPVSIHESRTIVSTRDGLDEVELPFDVPQGAGGGWPRLDFDARSGGEIVAADASSPRRPRTRVALSKTLARGQTHLLEIDITVAEGELPRPHYILIPERTVERARLRVRFDKAALPRWVRRVEAEPVRAFDPPHDDGQWLVPDRSGEVGVEFRRLCLQLGYGIQWGTSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2K0</accession>
    <name>D3Q2K0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkaline phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4284</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019504.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4284"/>
    <dbReference type="EnsemblBacteria" id="ADD43933">
        <property type="protein sequence ID" value="ADD43933"/>
        <property type="gene ID" value="Snas_4284"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4284"/>
    <dbReference type="eggNOG" id="COG1409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_648770_0_0_11"/>
    <dbReference type="OrthoDB" id="1242748at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PPA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="PTHR22953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048584" evidence="1">
        <location>
            <begin position="34"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="165"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="423" mass="45534" checksum="201373995EA9AB61" modified="2010-04-20" version="1">MPKPRKLRQRLLTATGAVILIATVGFVATESSANQNSADDAPTVPKLTDMVTQVAEPGAKEAPISASGTGSKAAKRELCHDGASWQRFRFTELDLNGEDSLTVTGSEGGTFTFTNRHWPGKAFYSRAFSGECVTVEPKLSDKDSGYEIDAFQYGSKALTKETVTVAGAGDICGDACNQTDDLITNINPASVFTAGDNAYEDGTLDEFQEQYDPTWGAFKDKTRPAPGNHEYHTDGEGYYEYFGDNAGEAGKGYYSYDVGDWHFVAVNSEIDFDPDSEQGQWLADDLASNTKPCTAAYTHHPRFSSGEHGDDSGMDDIFSALYDNQADLFITGHDHHYERFAPAAPDGSQDDDKGLRSFVIGTGGRALYDVPGGSDGPSEVFNNDTFGVGKFDLTATGYSMDFVPVAGRDFTDHVEGGCHKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2T1</accession>
    <name>D3Q2T1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021403.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6210"/>
    <dbReference type="EnsemblBacteria" id="ADD45832">
        <property type="protein sequence ID" value="ADD45832"/>
        <property type="gene ID" value="Snas_6210"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6210"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_0_4_11"/>
    <dbReference type="OMA" id="FEPEVIC"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="302" mass="31107" checksum="681D8EDC9F17EC65" modified="2010-04-20" version="1">MSDVVVALDVGGTSMKCALVDVNGRVLHSETRVTPREHGPEAVIKSIVDTAVELAATPGYRARAVGLVVPGPVDNERGIAVYSSNLGWRDVPFRQLVEAELGLPTALGHDVRAGGLAEARLGAGRGSRQLLFVAIGTGIAGAHIIDGSGLSGAHGAACELGHVVVRPDGPKCGCGQYGCVESLASAVQFERRYAEASGTAREAMDIIAAVDTDPIAQRVWRETIEVLADGFLLGIALLDPDTIVVGGGLAKSGDALLTPLRTALTARATFHTVPRLVAAELGREAGCVGAALLGLERLEDGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Z2</accession>
    <name>D3Q2Z2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="13">FBP aldolase</shortName>
            <ecNumber evidence="5 13">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Snas_0244</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="5 13"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015533.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0244"/>
    <dbReference type="EnsemblBacteria" id="ADD39962">
        <property type="protein sequence ID" value="ADD39962"/>
        <property type="gene ID" value="Snas_0244"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0244"/>
    <dbReference type="eggNOG" id="COG0191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036923_1_0_11"/>
    <dbReference type="OMA" id="PRTWGKL"/>
    <dbReference type="OrthoDB" id="827430at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006411">
        <property type="entry name" value="Fruct_bisP_bact"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559">
        <property type="entry name" value="PTHR30559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01520">
        <property type="entry name" value="FruBisAldo_II_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="11">
        <location>
            <begin position="250"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="11">
        <location>
            <begin position="271"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD39962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="341" mass="36329" checksum="3D9481AB09F0106D" modified="2010-04-20" version="1">MPIATPEVYADMLDRAKNGAFAYPAINVSSSQTLNAALAGFAEAESDGIIQVSTGGADYFSGPTVKNMVSGSVAFAEFAREVAKNYPVNIALHTDHCPKDKLDGFVRPLLDISAERVKGGQEPLFQSHMWDGSAVPLDENLRIAEELLAKTAAARIILEIEVGVVGGEEDGVVGAIDEKLYTTVEDGLATAAALGSGEKGRYMTALTFGNVHGVYKPGNVKLRPEILKEIQEAVGAKVGKTKPFDLVFHGGSGSLLEEIRSAVDYGVIKMNVDTDTQYAFTRPVADHMLKNYDGVLKIDGEVGNKKKYDPRAYGKAAEAGMAKRVVEACENLRSVGTTAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q375</accession>
    <name>D3Q375_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0327"/>
    <dbReference type="EnsemblBacteria" id="ADD40045">
        <property type="protein sequence ID" value="ADD40045"/>
        <property type="gene ID" value="Snas_0327"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0327"/>
    <dbReference type="eggNOG" id="COG0510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1029116_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="57"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="274" mass="29214" checksum="A481FD95C7684287" modified="2010-04-20" version="1">MTASVEVPQYVAEETTARWPNVGPQWVSEAPGELRQLCEQYGAIPETVLPARYGLVVAVQAKDRELIMKGSPDPDGPNQVKVMSALADLQVGPTILESFSTDTGFWTIMTRIKPGEPLRNLGASLAPPDKLATILRPLVNQPSPSSTLPYIGDWLRDRLEDDALSDLAPGRTVASETERSEALSVLSELTDAGAQGLCHGDTSPGNILTGENGKLYLIDPRGMRGEAAYDVAVLGLKSAMTVSPETRVSDLAKAVGVDVGRAERWAAIALAARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3A7</accession>
    <name>D3Q3A7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2259</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017519.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2259"/>
    <dbReference type="EnsemblBacteria" id="ADD41948">
        <property type="protein sequence ID" value="ADD41948"/>
        <property type="gene ID" value="Snas_2259"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2259"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_0_3_11"/>
    <dbReference type="OMA" id="HIAHPYM"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048205" evidence="1">
        <location>
            <begin position="42"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="59"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="416" mass="44674" checksum="7E2A6CD5B4B57D15" modified="2010-04-20" version="1">MSNTSSSPAPLSRRAALGLVGGGALAASGLATVAMPSRATAAGNEKLPPDTLPGGAYDRFVRKLAEADKFSGTILLTYRGEKVLSRSYGLADREKSVPNRANTIFALASASKPFTGLAIVQLAEQGKLSFHDTVGTYLDGFADDIAKTVTIHHLLLHTSGLDVPLDDEEFLENHHKWDSAAEVMSETMRIIKKHPLAFTPGTRNQYSNAGYSTLGAVVEAVSGKSFGDYVKEHIFEPAGMRRSAYYTRPQWMKSARFAHPYWLDASGERRDALTSDPVLGGVPNAGRSFIGGGGGNGFSTAPDLVRFAEALDDGTLLGPAFREVYWSGKYPLAPRSRSSETDVRQAFQAYGAPAGVIGGCRMFGHGGGAAGEATHWNIYRDRDWVGVILCNYGPIGPNEYTPIPEMLERERQAILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3C9</accession>
    <name>D3Q3C9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017541.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2281"/>
    <dbReference type="EnsemblBacteria" id="ADD41970">
        <property type="protein sequence ID" value="ADD41970"/>
        <property type="gene ID" value="Snas_2281"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2281"/>
    <dbReference type="eggNOG" id="COG2072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039832_0_0_11"/>
    <dbReference type="OMA" id="ETRILWA"/>
    <dbReference type="OrthoDB" id="324612at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="494" mass="51287" checksum="425F4CFC30BE7342" modified="2010-04-20" version="1">MSEYEQSSAEPVVVIGAGPVGLAAAAHLVERGITPVVLEAGFGPGAAIREWGHVRVFSPWRFNIDAAARRLLEAEGWSAPNAAHLPTGDELVDDYLKPLAELPRLAPHVHFDTRVVAVARHGIDKTRTVGRDGRPYLVRTRTGAGEYRDVVARAVIDASGTWGKSNPLGAHGLPAPGEAEASSYMAGALPDILGADRERFAGRHALVVGMGHSAANALLALADLAEVAPGTRITWVVRGRSAARLYGGGDADALPERGKLGTRVKQLVADGRLTLIKNFTIDRFEPATDGPLAVVGRSGDEPVKLDVDVVVAATGFRPDVDMLREVRLDLDPAVEAPSQLAPLIDPNFHSCGTVPPHGERVLAHPDEGFYVAGMKSYGRAPTFLMATGYEQVRSIVAAIAGDREAADEVHLELPETGVCSSSPTVEDADGNVTFAEASGGCGTGDEGSSCGTAAAPRGLTTGVLHGYSGEGATLPVVQEAAPAGGCCGGEPATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3D9</accession>
    <name>D3Q3D9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2291</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017551.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2291"/>
    <dbReference type="EnsemblBacteria" id="ADD41980">
        <property type="protein sequence ID" value="ADD41980"/>
        <property type="gene ID" value="Snas_2291"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2291"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_3_11"/>
    <dbReference type="OMA" id="AFRYGQF"/>
    <dbReference type="OrthoDB" id="1619224at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="277"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="88"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="311" mass="34124" checksum="619F08C2003DE7F3" modified="2010-04-20" version="1">MTAMTQSVGNPQPRARRRRRRLGSSGRDAWPFVLPALLPVMLFSVYPLVYGVFLGFTDAEAGLNVETNFNGVDNYIKLGGNELFWSSFKIGLIWAFSVTILQFLASLGLALLLNLDLRLRWLARTLALVPWAMPPVIIAIMWQLMLNPDYGPVNRSLEALGLPGGVNWLGDGSTALAVVIIVGVWAGMPQTTITLLAGLQAVPVELHEAAAIDGANTRRRFWHVTLPAIRPVVVAITTLDLIWNFNSFALVFVLTAGGPGGTTMLPSLFAYNEAFRYGNFGYAAAMGNVMVIVIGAILFFYLRGQMRRRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3F6</accession>
    <name>D3Q3F6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017568.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2309"/>
    <dbReference type="EnsemblBacteria" id="ADD41997">
        <property type="protein sequence ID" value="ADD41997"/>
        <property type="gene ID" value="Snas_2309"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2309"/>
    <dbReference type="eggNOG" id="COG5470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145407_4_1_11"/>
    <dbReference type="OrthoDB" id="1534521at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010753">
        <property type="entry name" value="DUF1330"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07045">
        <property type="entry name" value="DUF1330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1330" evidence="1">
        <location>
            <begin position="3"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="99" mass="11139" checksum="0328C09E57C5C6AD" modified="2010-04-20" version="1">MSYYLIGMTNTANPAAMKDYVERVRPMVENHGGQFVLEAAIEQVMEGAFPATNGVVMRFDSAEAAQRWYSSPEYIELKKVRTDNGESILVLARPYNSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3J8</accession>
    <name>D3Q3J8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thymidylate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017610.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2353"/>
    <dbReference type="EnsemblBacteria" id="ADD42039">
        <property type="protein sequence ID" value="ADD42039"/>
        <property type="gene ID" value="Snas_2353"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2353"/>
    <dbReference type="eggNOG" id="COG0125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092360_0_0_11"/>
    <dbReference type="OMA" id="CQYASIR"/>
    <dbReference type="OrthoDB" id="1585072at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="1">
        <location>
            <begin position="14"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="204" mass="22771" checksum="B4AFB8F5F20AFE02" modified="2010-04-20" version="1">MARETRQATIALVGIDGAGKTTQARWLKRWLTQLGHPVRYRMVASGRRVLGNTARRLGRPDSVALLGPGMAIRAETLLRYWNLTVGNGGGILIADRYAVCQYARTRVVYPRLEPWARRLLGRVPPPDLTLYLDVAPETAHLRVKTRGIDEEPVDSLAAMDSAYRSLPEFASFAIVDANRDPEEIAETIRDEVRTALPRLLDGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Q7</accession>
    <name>D3Q3Q7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4327</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019545.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4327"/>
    <dbReference type="EnsemblBacteria" id="ADD43974">
        <property type="protein sequence ID" value="ADD43974"/>
        <property type="gene ID" value="Snas_4327"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4327"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_0_3_11"/>
    <dbReference type="OMA" id="HAFLMDR"/>
    <dbReference type="OrthoDB" id="1534467at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="154" mass="17599" checksum="92D56906A814CF15" modified="2010-04-20" version="1">MDELDARIVRLLQANARQSNRELARTLGIAPSTCLERVRTLTRRGVIRGYHAEVDLPAMNRDVQALVSVQMRRHSRPIYEAFRDAAKNWREVITLFVVSGEHDIVMHVAVPDSDSLHSFLVDRLATRQEVARFQSSLIFQRIHNNVLDVLDSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3S3</accession>
    <name>D3Q3S3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent pyridine nucleotide-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019561.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4343"/>
    <dbReference type="EnsemblBacteria" id="ADD43990">
        <property type="protein sequence ID" value="ADD43990"/>
        <property type="gene ID" value="Snas_4343"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4343"/>
    <dbReference type="eggNOG" id="COG1252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021377_8_1_11"/>
    <dbReference type="OMA" id="YFNQCIS"/>
    <dbReference type="OrthoDB" id="403436at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="9"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="414" mass="44497" checksum="EE6D75F889D95996" modified="2010-04-20" version="1">MSTSTRKHRIVILGAGYAGSITASRLAGHLRRDEVDITVVNAVPDFVERVRLHQLAAGQELAKVPLARVFRGSGIRLRLGWVRGLDTEQRRVTVDTDGGVDAIGYDTLVYALGSQAAVAPVPGVDTHGFSVSTRTEALRLRDRIAATGGTGTLTVVGGGLTGLEVASEMAESHSRLRVRMVTDAELGDWLNPRARAYLRQVFARLGIETVTAKVAEVREDAIVTTDGDVLDSDTTVWTTGFAVPGLATESGLATDADGRIHIDQTMRSASHPDVYAVGDAAVVRGPQGTILRMACGTGAPMALQAADAIAARLSGRRPHRFVFRYIHQNISLGRRDGLIQYVTSDDRPKNTILKGRAAVMYKEMVNGWAVTFARHAGPYLPRPRRRLVAASDRRGQSVDDLGAGELGERLAAHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3T2</accession>
    <name>D3Q3T2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019570.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4352"/>
    <dbReference type="EnsemblBacteria" id="ADD43999">
        <property type="protein sequence ID" value="ADD43999"/>
        <property type="gene ID" value="Snas_4352"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4352"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079347_0_0_11"/>
    <dbReference type="OMA" id="PLYRYQL"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="169"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="274" mass="29487" checksum="1E430B3EA7521384" modified="2010-04-20" version="1">MLTTTLLARHRDFAVHAVHCRDDHRGWAAETVRDDHRIVLVRRGGFRRRADGASGYVDVTCGYVGLPGQEERFAHPVNGDVCTSIHLDRALWAGIVGDTAAPTSVRVDAPLDLAHRGLLRAAEVRDVDFAVAEQLVHLAALAVRRAVGGGVGGRDASGAVGRRDAGLVAQAREAIAAGHPQAAGLTTLAQLLRVSPYRLSRAFSAHTGMSVTRYRNRLRTGRAVDAIEAGETRLGELALRLGFADQAHLTRTVKQHYGHPPVALRELLRRAGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3W8</accession>
    <name>D3Q3W8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable cytosol aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucine aminopeptidase</fullName>
            <shortName evidence="8">LAP</shortName>
            <ecNumber evidence="8">3.4.11.10</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Leucyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pepA</name>
        <name evidence="10" type="ordered locus">Snas_4388</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.</text>
            <dbReference type="EC" id="3.4.11.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="8"/>
    <dbReference type="EC" id="3.4.11.10" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019606.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4388"/>
    <dbReference type="EnsemblBacteria" id="ADD44035">
        <property type="protein sequence ID" value="ADD44035"/>
        <property type="gene ID" value="Snas_4388"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4388"/>
    <dbReference type="eggNOG" id="COG0260">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013734_2_0_11"/>
    <dbReference type="OMA" id="MKNTGPR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="9">
        <location>
            <begin position="332"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD44035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="490" mass="50597" checksum="F2D97EC8871D75F1" modified="2010-04-20" version="1">MTRLIASAVDPATLDVDVLVVGVHSGDDGPFLAPGAETVSTAWSDLTETLELLGAKGSAGSVSKLPSGGRVAAKLLVAVGLGEPDENGSVDDETLRRAAGVAARAAVGRESLAFALRADAELLATGAILGAYQFDGYKSDDPDRKEPVASITVAGPDAQLERAGSIAAGVTAARDWVNTPANLLRPPDLAADVERRATEAGLGVEVLDEHALTEGGYGGILAVGMGSAAKPRLVRLTWRPEGASKHVALVGKGITFDTGGISIKPANGMWDMKGDMAGAAAVAGTMLAVAALKPAVNVTAYLALAENMPSGDAYRPGDVVTIYGGKTVEVLNTDAEGRMVLADALVRAAEDEPDVLYDTATLTGGQVIALGKRTAGIMGTDEECERVRAAGEKVGEPGWPMPLPEEIKKTMESPIADIKQVSANMERSGHMLQGGIFLAKFVPEDLPWAHIDIAGPGDHSGDAYGYTVSGGTGRPVRTLVELVEEHARRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q442</accession>
    <name>D3Q442_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lysyl-tRNA synthetase</fullName>
            <shortName evidence="6">LysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lysS</name>
        <name evidence="9" type="ordered locus">Snas_6309</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6 7">Binds 3 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6309"/>
    <dbReference type="EnsemblBacteria" id="ADD45927">
        <property type="protein sequence ID" value="ADD45927"/>
        <property type="gene ID" value="Snas_6309"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6309"/>
    <dbReference type="eggNOG" id="COG1190">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008255_6_0_11"/>
    <dbReference type="OMA" id="EIFGEKC"/>
    <dbReference type="OrthoDB" id="63621at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="185"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="501" mass="55762" checksum="A256299C35EBBC26" modified="2010-04-20" version="1">MTENPSTTATEDDIPEQLKVRHAKRADMLAEGAKPYPLGVKRTTTLKRLREEYGHLEAEASTGVIASVTGRVIFVRTGGKLCFATIREGDGTQLQLMLSLAKVGEESLGEWKRLIDIGDVVAVTGEVITSKRGELSVMADEWEMAAKALRPLPVAHKPMSEETRVRQRYVDLIMRPEARDTARNRAAVVHTLRDIMHQRDFMEVETPVLQAIASGANARPFTTHFNAINMDVYLRIALELYLKRCVVGGIDRVFEISRNFRNEGADSTHSPEFSMMEAYEAYGDYRSIGRLTRDLVVGCAESVFGSTTVTHADGTELEFGGEWREVTLFGALSEALGEPVSIETPYDRLVAFAEKTDLEVNPVWGPGKLAEELFEHLVTDTLVNPTFVLDYPEETSPLTAAHRDTPGLTEKWDLYVRGVELATGYSELIDPVVQRERFEQQARLAAKGDDEAMKLDEDFLRAMEYGMPPTGGMGMGIDRLLMALTGLGIRETILFPFVKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q454</accession>
    <name>D3Q454_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6321</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UDPGP type 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021510.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6321"/>
    <dbReference type="EnsemblBacteria" id="ADD45939">
        <property type="protein sequence ID" value="ADD45939"/>
        <property type="gene ID" value="Snas_6321"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6321"/>
    <dbReference type="eggNOG" id="COG1210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_1_0_11"/>
    <dbReference type="OMA" id="MHYVRQG"/>
    <dbReference type="OrthoDB" id="1402673at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02541">
        <property type="entry name" value="UGPase_prokaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005771">
        <property type="entry name" value="GalU_uridylyltTrfase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43197">
        <property type="entry name" value="PTHR43197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="4">
        <location>
            <begin position="12"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="32810" checksum="C7F2FDA14602596D" modified="2010-04-20" version="1">MPASNNESPAFKAVIPAAGFATRFLPATKAVPKELFPVIDKPVLQHVVEEAVAADVRDVILITGRGKTSMVDHFDRRPDLEQRLVEKGDTTRLASIIEASDLVDIFTCRQSEPLGLGHAVSYAESHVGEEPFAVLLADEFTAPTDRLLPRMFEKQKETGGIVLALKEMPREEIHRYGVAAIEERGDSDVVTVTGLVEKPDPAEAPSNLILIGRYVLPSAIFDAIRKTKPGRGGEIQLTDAMELLLKDGMPVHGIVFTGTRHDTGEPEGYLRTIVELAWQREDLTTFKEWLSDFMAKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q478</accession>
    <name>D3Q478_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6346</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6346"/>
    <dbReference type="EnsemblBacteria" id="ADD45963">
        <property type="protein sequence ID" value="ADD45963"/>
        <property type="gene ID" value="Snas_6346"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6346"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="HERRVTH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="BTAD" evidence="3">
        <location>
            <begin position="96"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1034" mass="112011" checksum="5B452861534170E3" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q484</accession>
    <name>D3Q484_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6353</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021540.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6353"/>
    <dbReference type="EnsemblBacteria" id="ADD45969">
        <property type="protein sequence ID" value="ADD45969"/>
        <property type="gene ID" value="Snas_6353"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6353"/>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_5_11"/>
    <dbReference type="OMA" id="AFHVVDD"/>
    <dbReference type="OrthoDB" id="1911275at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="22"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="232" mass="26100" checksum="093656F935B03D2D" modified="2010-04-20" version="1">MTTPPPESFVYESRTVDPPTRNSTAEFVAGLLRTEIADGKRQPGDKLPEAELCELHQVSRNTLREAFQLLTHERLVIHNLNRGFKVRRPSAEDLSDIYRVRRVIECGAIRSAVIVPERLAGLQRAVADGERAAKQHDGRAVGSANIQFHRSIGSLAESARIDEVMNQVLAELRLVFHVMGNHGDFHLPYLPRNREILDCLAEHDIMRASQLLSNYLDDAEEQLQAAYEEADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4P9</accession>
    <name>D3Q4P9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Substrate-binding region of ABC-type glycine betaine transport system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2396</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017650.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2396"/>
    <dbReference type="EnsemblBacteria" id="ADD42079">
        <property type="protein sequence ID" value="ADD42079"/>
        <property type="gene ID" value="Snas_2396"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2396"/>
    <dbReference type="eggNOG" id="COG2113">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072064_0_0_11"/>
    <dbReference type="OMA" id="QVIAEEW"/>
    <dbReference type="OrthoDB" id="770506at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049697" evidence="2">
        <location>
            <begin position="22"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="30"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="314" mass="35368" checksum="385208C38D383092" modified="2010-04-20" version="1">MRSKVIAALAVGVMAATSACGGATTDSGGDKVNIAINPWTGYEASAAVIQYLLENELDVEVDTKELKEENAWQGFEREGDDGVDVIVEDWQHTDLRKKYIDDKKVAVNAGTTGNKGLIGWYVPTWMLKKYPGIDEWKNLNKYAKDLETSESKGKGQLLFGDKSYVSNEEALIDNLGLDYEVVVGGSENALIEAAQQSEKQQEPLLFYFWDPHWLFEDVELTRVKLPEYSDDTTQCPTDPKKVKCDYPEMDLETIVSKDFADNGGDAYKLVKNFEWTNEDQNSVALDILKNDMKPEEAAEKWVNANKDVWKKWLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4W3</accession>
    <name>D3Q4W3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2460</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017714.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2460"/>
    <dbReference type="EnsemblBacteria" id="ADD42143">
        <property type="protein sequence ID" value="ADD42143"/>
        <property type="gene ID" value="Snas_2460"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2460"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100874_1_0_11"/>
    <dbReference type="OMA" id="VERDVRW"/>
    <dbReference type="OrthoDB" id="1345242at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="5"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="165" mass="18129" checksum="0FBF22FE542FAF96" modified="2010-04-20" version="1">MSSMNFRHAVRAIILDERDRVLLCRFVVPDPPGTMTVWVAPGGGVDPGETRQQALRRELMEEVGLALETDPPLVWNQKTAGPEYTPGYDGTINDYYLVRASAFDPRGTFTDEQLAAENIAGWRWWPLGDIVEHDGADLFSPRDLATPLAALIADGVPARPVSLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q531</accession>
    <name>D3Q531_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019651.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4435"/>
    <dbReference type="EnsemblBacteria" id="ADD44080">
        <property type="protein sequence ID" value="ADD44080"/>
        <property type="gene ID" value="Snas_4435"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4435"/>
    <dbReference type="eggNOG" id="ENOG5032TBA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072020_0_1_11"/>
    <dbReference type="OMA" id="FRYHIVS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055070">
        <property type="term" value="P:copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021522">
        <property type="entry name" value="MctB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11382">
        <property type="entry name" value="MctB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048664" evidence="2">
        <location>
            <begin position="39"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="295" mass="30316" checksum="E7CDF7A9849EDFAB" modified="2010-04-20" version="1">MINHRFHLVAVVAIFLAVAVGLGLGMVGVGGSAGSAHAEAEQADTQRLRAEVDRLGTASEKARDFATGVAPVTLAELLADERVLLVGIGGAKDAELDAISDTLEYSRATSAGTLNFTDAFTDPDNSASLIDLAAKLTPKGVKPPNDNNGVETVSALLAMSILDKSEVSASERDRLVSALEGLKMVDVAENLSDERATAVVIVSGKPESGHQPSVVTASDRFGREGATVLAAAKPDGVIEAVREDPARSKRISTVDNVDSPQGRVTAALALPSTIEGETGHYGTGESANAVVPVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q542</accession>
    <name>D3Q542_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Tyrosyl-tRNA synthetase</fullName>
            <shortName evidence="7">TyrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tyrS</name>
        <name evidence="9" type="ordered locus">Snas_4446</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4446"/>
    <dbReference type="EnsemblBacteria" id="ADD44091">
        <property type="protein sequence ID" value="ADD44091"/>
        <property type="gene ID" value="Snas_4446"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4446"/>
    <dbReference type="eggNOG" id="COG0162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024003_0_3_11"/>
    <dbReference type="OMA" id="YMMAKDS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02006">
        <property type="entry name" value="Tyr_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024107">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'HIGH' region" evidence="7">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="7">
        <location>
            <begin position="227"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="416" mass="45557" checksum="AAD8A1C789E896A1" modified="2010-04-20" version="1">MNIFDDLQWRGLIQDATDSDALRAHFEAGPVRFYVGFDPTAASLHVGHFTQVLTARRLQLAGHRPLLLVGGATGQIGDPKESGERVMNSPEVVAGYLDRIREQMRPFVTYDGDNAAVLVNNLDWTGRMNAIDFLRDVGKHFPVNKMLARDVVKARLESGISFTEFAYQLIQANDYYNLHQEYGCSVQFGGSDQWGNITAGVDFIRRKGSGPVHAFVTPLVTKADGTKFGKTEGGAVWLDPELTTPYAFYQFWVNVDDRDIGTYLRRFSFKSHDEILELDKATAEKPAARAAQRALAEELTTLLHGETECAQVIAASKALFGRGELSELAPSTLESALSEAGLVTATDDSPITALFKETGLTASTSEARRAIADGGAYVNNVRITDVDAKLADVELLHGRFAVLRRGKKNIAGVTRS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-08-10" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q556</accession>
    <name>PSA_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Proteasome subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">20S proteasome alpha subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Proteasome core protein PrcA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">prcA</name>
        <name type="ordered locus">Snas_4460</name>
    </gene>
    <organism>
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein degradation; proteasomal Pup-dependent pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019676.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D3Q556"/>
    <dbReference type="SMR" id="D3Q556"/>
    <dbReference type="STRING" id="446470.Snas_4460"/>
    <dbReference type="MEROPS" id="T01.980"/>
    <dbReference type="EnsemblBacteria" id="ADD44105">
        <property type="protein sequence ID" value="ADD44105"/>
        <property type="gene ID" value="Snas_4460"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4460"/>
    <dbReference type="eggNOG" id="COG0638">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071031_0_0_11"/>
    <dbReference type="OMA" id="QIYRLPH"/>
    <dbReference type="OrthoDB" id="1243753at2"/>
    <dbReference type="UniPathway" id="UPA00997"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019941">
        <property type="term" value="P:modification-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00289_B">
        <property type="entry name" value="Proteasome_A_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022296">
        <property type="entry name" value="Proteasome_asu_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599:SF69">
        <property type="entry name" value="PTHR11599:SF69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03691">
        <property type="entry name" value="20S_bact_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0647">Proteasome</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000397175" description="Proteasome subunit alpha">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="228"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="265" mass="28970" checksum="2943DE37A9CDF031" modified="2010-04-20" version="1">MAMQFYTSPEQIMRDRSEYARKNISRGRNTVVLSYAGGVLFVAENISTTLHKISELYDRIGFAAVGRYNEFENLRTAGVRMADTRGYAYDRRDVKARPLAQAYAQTLGAIFTEQTKPFEVEICVAGVGSSPDDDELYRLTYDGSINDEPGYLVMGGQADKLTSVLKEGHNFDLDLTGAFRLALKALSSIGGENGKDRTVGAELLEVAVLDREREGRVFRRILGPALDALMPESSGDAETPDTGGSGQHSDEPSKPDAEGGEKEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5D0</accession>
    <name>D3Q5D0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019750.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4534"/>
    <dbReference type="EnsemblBacteria" id="ADD44179">
        <property type="protein sequence ID" value="ADD44179"/>
        <property type="gene ID" value="Snas_4534"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4534"/>
    <dbReference type="eggNOG" id="ENOG5032RNQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151863_0_0_11"/>
    <dbReference type="OMA" id="ASCFLVH"/>
    <dbReference type="OrthoDB" id="1959396at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025242">
        <property type="entry name" value="DUF4193"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13834">
        <property type="entry name" value="DUF4193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="99" mass="10947" checksum="808997D46FE2618B" modified="2010-04-20" version="1">MATDYDAPRRDTEESGDDSLEELKARRADAQSGSVDVDEAEVAENFELPGADLADEELTVKVLPMQNDEFRCSSCFLVHHRSQLASQKKGKLICRDCAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5U7</accession>
    <name>D3Q5U7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0532"/>
    <dbReference type="EnsemblBacteria" id="ADD40246">
        <property type="protein sequence ID" value="ADD40246"/>
        <property type="gene ID" value="Snas_0532"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0532"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014914_0_0_11"/>
    <dbReference type="OMA" id="GWRTMPY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="226"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="853" mass="93885" checksum="AA6528C8B0E90C24" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6C3</accession>
    <name>D3Q6C3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017869.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2620"/>
    <dbReference type="EnsemblBacteria" id="ADD42298">
        <property type="protein sequence ID" value="ADD42298"/>
        <property type="gene ID" value="Snas_2620"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2620"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="LEIPQGC"/>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="8"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="348" mass="37531" checksum="C458BB9CE2F97EBD" modified="2010-04-20" version="1">MNEATPVLRIDKLSVDYGYDSRAVHALREVSLTLHSGEVLGLAGESGCGKSTLAYAATRLLPPPGLITGGRVLFSTADGGTLDLLGASDDELRAVRWEEIAIVFQGAMNSLNPVYRIGKQLTDVIAAHRPKTGRAAARDRAVELLDHVGISADRLRAYPHELSGGMRQRVMIAMALALEPRVIIMDEPTTALDVVVQRQILEQITELKTRLGFAVIFITHDVSLLIEIADRIAIMYAGQIIEDATAAEVYHAPRHPYTSGLLHSFPPLHGPKRLLGGIPGSPPDLQALPSGCAFQPRCQLAFDRCGTDRPALSATAFGPDEPLRRVACFHHDADPPLIPDTLSARLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6L1</accession>
    <name>D3Q6L1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PLD phosphodiesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019825.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4611"/>
    <dbReference type="EnsemblBacteria" id="ADD44254">
        <property type="protein sequence ID" value="ADD44254"/>
        <property type="gene ID" value="Snas_4611"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4611"/>
    <dbReference type="eggNOG" id="COG1502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047394_1_0_11"/>
    <dbReference type="OMA" id="AYNHNKF"/>
    <dbReference type="OrthoDB" id="1881748at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049588" description="PLD phosphodiesterase domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="350"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="418" mass="46004" checksum="3E7114A940C33EB4" modified="2010-04-20" version="1">MRLSRVLTFAAAAALAAVAVAVPSIAQAEEADPVIDHAVFNNPTGTTAEKYAIFIQFGRLIDRVPAGETISMSFFGLDKVTDSDSPDTPDLTAKLVAAHERGVKVRIITDNGNVGNDAWNKLTAALGTDDSKGSWIVHCSDKFADNPDRGCIGTRVKEWSNGPLYAYNHNKFATFSAVKMNGGSTASNVVFTGSSNIGSWDAVTAFNNMFTFSDEPGYKIFEKYFEDLRVTRSSAEGNNNYYTDTGSTSKYRMFFFPRHERSGQPFEDPGSDTVYNTLQSVDPSCKYQEPDGSWHQTDVRVAMLAFNRPAIAQKLAQLKKNGCWIDVVYSSANADVLNALSGIQTTKCQGALRVHSKYMLIDGGFDDDITPRVYTGSHNYAWSALRQSDETLVRMTGRELHTEYLNNFYDTRTACKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q751</accession>
    <name>D3Q751_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2645"/>
    <dbReference type="EnsemblBacteria" id="ADD42322">
        <property type="protein sequence ID" value="ADD42322"/>
        <property type="gene ID" value="Snas_2645"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2645"/>
    <dbReference type="HOGENOM" id="CLU_1065220_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="277" mass="30442" checksum="449528A4662FC259" modified="2010-04-20" version="1">MTTSPYRGHEMSPRVEDAAALKKQLASARRFKIVALVIGLGYPVFYFLITYQARPESGNDWAAFITGAVCGTALFVSIPLAVGINKGRKAAERLYLNGTQLTIVGMPRKTETVLDLTRARAEVRLDWLVDSDLVNSKALTEAQRQTRIEMVHKALDKQIANGTAPCVYVPVLLLYRDDGHKFPILLADNKTRQIRAVGEIHMLERAMQFAADPAIQHAAGQLRTIARWQRLPAIYEARPDTIPATPTDHPATAPPPPTPVIRGEPAPETTVTGPPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7G3</accession>
    <name>D3Q7G3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018005.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2758"/>
    <dbReference type="EnsemblBacteria" id="ADD42434">
        <property type="protein sequence ID" value="ADD42434"/>
        <property type="gene ID" value="Snas_2758"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2758"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_10_0_11"/>
    <dbReference type="OMA" id="VDEWNAT"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049770" evidence="1">
        <location>
            <begin position="26"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="423" mass="44975" checksum="9145A8DF32DD5C55" modified="2010-04-20" version="1">MRIRALALATVLVLTASGCATSSFGDEPGKTLTVLTHYGSEPHKSGLKKLVDEWNRTHPEVQVKTQSVLYNELLQTVTARHASGQTPDIINAYSLWGGQLAAADVLDEPPTDVATDIRDEYSPAASEAVTVDDQVLGYPTEMQTYALIYNKKLLAKAGVTEPPKTWDELEDIAERTTVTDDSGNLDVAGFGLTTDFSDTAVVHPFASLLQAAGGRYMNADGSAAFDSKAGQRALSLQKQLVESGSADPGLNTIKAFPSNRVAMTINAGYWIGVLKGMMGDDYENVGVAPIPGPKAGDKGSLAYGFFTGVSSHSDQKDDAWEFLRWLNAEQAADGATRMGAFQFGAGSIPARVSDSEALTADDPNFEPFVQAMDYALPEPNPRGGQQMKTALQGSIQSVWTGDLSVAEALRSAAAEADATLNQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7I5</accession>
    <name>D3Q7I5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulatory protein, MarR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019898.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4684"/>
    <dbReference type="EnsemblBacteria" id="ADD44327">
        <property type="protein sequence ID" value="ADD44327"/>
        <property type="gene ID" value="Snas_4684"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4684"/>
    <dbReference type="eggNOG" id="COG1510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120349_2_1_11"/>
    <dbReference type="OMA" id="RDFCEFC"/>
    <dbReference type="OrthoDB" id="1646730at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="157" mass="18095" checksum="8E74C6DD4B0986FA" modified="2010-04-20" version="1">MSTDEDRTERHAFAEELGLYMESKGLPRIPGRVLGWLLVCEPEHQSAEELAEALTTSRGSISMATQYLQRAGVVERYPVPGSRRIYYRIRPGFWLNEASEKAKVAEEAVKLAERGLSTMADSSEDSRARLRDMRDMYSFLATEYARIENKWRQMQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7K4</accession>
    <name>D3Q7K4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gas vesicle synthesis family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4703"/>
    <dbReference type="EnsemblBacteria" id="ADD44346">
        <property type="protein sequence ID" value="ADD44346"/>
        <property type="gene ID" value="Snas_4703"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4703"/>
    <dbReference type="eggNOG" id="ENOG50334QT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142302_2_1_11"/>
    <dbReference type="OMA" id="RYRRGAQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031412">
        <property type="term" value="P:gas vesicle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008634">
        <property type="entry name" value="Gas-vesicle_GvpO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05800">
        <property type="entry name" value="GvpO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="114" mass="11961" checksum="E92FC1201E52F4C2" modified="2010-04-20" version="1">MARTSRTKDNEPDDAKADGKSTSSPSLGAAKAARLAAEQVAELTSREPIGIVGVEARDGGWRVDIEVIEAARIPSSTDMLATYSADLDADGALLSCRRASRYLRGSNYSNGDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7R5</accession>
    <name>D3Q7R5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019978.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4765"/>
    <dbReference type="EnsemblBacteria" id="ADD44407">
        <property type="protein sequence ID" value="ADD44407"/>
        <property type="gene ID" value="Snas_4765"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4765"/>
    <dbReference type="HOGENOM" id="CLU_121293_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="165" mass="18765" checksum="6E35FDF17425B033" modified="2010-04-20" version="1">MSRREWYRTLESLVAEAVSPDGVITATVVKGQTLRLRLLPRTYTDYTACELESQLSTVVTTAFGAYREARRDFRERHGLGGHPGRDGPRTRLAAEARELTAQASSGQDWVRVWTRGLTDWRFALADNIIRSLSVGRFVDETLSAVHAATAEYQRKLFILRRQRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8A3</accession>
    <name>D3Q8A3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclase/dehydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018048.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2801"/>
    <dbReference type="EnsemblBacteria" id="ADD42477">
        <property type="protein sequence ID" value="ADD42477"/>
        <property type="gene ID" value="Snas_2801"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2801"/>
    <dbReference type="eggNOG" id="COG5637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079860_3_1_11"/>
    <dbReference type="OMA" id="NQIIQWE"/>
    <dbReference type="OrthoDB" id="1719670at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polyketide_cyc" evidence="1">
        <location>
            <begin position="10"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="145" mass="15928" checksum="72D4FFD6485253A6" modified="2010-04-20" version="1">MSNIVESITVNVPASDAYGQWSKFDELPKFMSGVSRVDLGPNGLTHWVIDIGGVTREFDAKVLTAETDRRVAWTSVEGPRHSGSVEFAPINESSTRVTAQLDVDPEGFVESAADKLGVLNLRLKKDLASFKNYMEDPANPHGERH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8D1</accession>
    <name>D3Q8D1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="5">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP cyclohydrolase I</fullName>
            <shortName evidence="5">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">folE</name>
        <name evidence="7" type="ordered locus">Snas_2829</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2829"/>
    <dbReference type="EnsemblBacteria" id="ADD42505">
        <property type="protein sequence ID" value="ADD42505"/>
        <property type="gene ID" value="Snas_2829"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2829"/>
    <dbReference type="eggNOG" id="COG0302">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049768_2_0_11"/>
    <dbReference type="OMA" id="VACVIDA"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="6">
        <location>
            <begin position="44"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="220" mass="24259" checksum="BDD39153878F1A2F" modified="2010-04-20" version="1">MASPAPNPANLSSLSEMKVPHAIPAQRTLRVVHDREDVDLDAAHKAVTDLLVALGRNPMSEHLADTPRRVAEAYAEMLTPREFNLTTFPNDEGYDELVLARGIPVQSLCQHHLLPFHGVAHVGYLPGERILGLSKLARVVELFARDLQVQERLTKQVADWLRDHLAPKGVGVVIEAEHMCMALRGVRATGSRTLTSAMHGQLRDDARSRQEFFALTGTNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8E8</accession>
    <name>D3Q8E8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2847</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2847"/>
    <dbReference type="EnsemblBacteria" id="ADD42522">
        <property type="protein sequence ID" value="ADD42522"/>
        <property type="gene ID" value="Snas_2847"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2847"/>
    <dbReference type="eggNOG" id="COG0559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039929_2_1_11"/>
    <dbReference type="OMA" id="MPEFGEF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="289" mass="28958" checksum="4A740FF0EDBDA8DF" modified="2010-04-20" version="1">MLDLYLIPVINGFAYGLLLFVVAAGLTLAFGVADVLNLAHGTVYVVGGYAAATLTDGSWGGLLLAIAVGCLAGAACGGLLSVAVAPLTGRGHLAQALLTFGIALVGGALLVYAFGADDLRPTLPEALTEPVLINGQRYSGYRLSMIGLGVILAVVIWFVITRTRAGARVRAMVDDPGMVASLGTNPRTILNGVMVAAGALAGTAGAIGAPLIGPGPGTANQVLLMSLVIVVVGGLGSVLGAFVAALVVGQVQALGPIVAETWAPYLLFVAMAVALLVRRPQSLLPGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8E9</accession>
    <name>D3Q8E9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2848</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2848"/>
    <dbReference type="EnsemblBacteria" id="ADD42523">
        <property type="protein sequence ID" value="ADD42523"/>
        <property type="gene ID" value="Snas_2848"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2848"/>
    <dbReference type="eggNOG" id="COG4177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031365_0_1_11"/>
    <dbReference type="OMA" id="SPFGMML"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="337" mass="35059" checksum="BAF9DEBEE3BB92C6" modified="2010-04-20" version="1">MTVLEQERTTTAPGRRAFNPLRLWPLAVVAVLACVPFIVDDYTLITGNRVLSLGLLAASVALLTGTAGLPSLGQAAPYGIGAYLAYNLAELDWTFAPLQVVAAAAAGALFNAVTGPVVVRTRGVVFLMVTLAVGEIAVVAAGKWESVTNGTDGTGRIPPGELIPGEPLVDDANLYWYALGVAVVVITAMVLVQRSRGGKLLHGSRDNEMRMRASGHRVSGYLLLTYIAAGAIAGVGGSVLATTQRYVSPSDMDFSVAALILLAVVIGGAFSITGALAGVLLVIVARDLIGNHLPGQGPLLLGILFIVAVYLLPNGLAGRLGDLTRLLTRKRDREEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8L4</accession>
    <name>D3Q8L4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonuclease H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4815"/>
    <dbReference type="EnsemblBacteria" id="ADD44456">
        <property type="protein sequence ID" value="ADD44456"/>
        <property type="gene ID" value="Snas_4815"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4815"/>
    <dbReference type="eggNOG" id="COG0328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095977_0_3_11"/>
    <dbReference type="OMA" id="NPGRSGC"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13456">
        <property type="entry name" value="RVT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="3"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="137" mass="14440" checksum="A92F319305793FE9" modified="2010-04-20" version="1">MSEIDKVIVEADGGSRGNPGPAGYGAVVLDETGQELMDRQGFLGIATNNVAEYSGLIAGLTAARELGAANVAVRMDSKLVVEQMNGNWKVRHPGLRPLAAEAAALVRQFDSVTFTWIPRADNTRADALANAAMDDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8V6</accession>
    <name>D3Q8V6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020119.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4907"/>
    <dbReference type="EnsemblBacteria" id="ADD44548">
        <property type="protein sequence ID" value="ADD44548"/>
        <property type="gene ID" value="Snas_4907"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4907"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055817_1_1_11"/>
    <dbReference type="OMA" id="FLIHESA"/>
    <dbReference type="OrthoDB" id="1847479at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043917">
        <property type="entry name" value="DUF5753"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19054">
        <property type="entry name" value="DUF5753"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="15"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="271" mass="30804" checksum="0B1D892B5A70CB9D" modified="2010-04-20" version="1">MVEGPLFTRKQLGIRLRELRHASGKTVEDIEVADIMGKSKLYYIEAGRQPKPSWPEIKELAELLGADTALRNELVRMAKDCLRSGWYVPFDVPQQFQPYLDLEGAATKLSFFEVEYVNGLFQTDAYTRAIQVGWGLKGAELDHTQTFRAQRKKRFWQRDPAPEVVLVMSEAAVRRQVGGPEVMAEQMVHLRKLAEKPNVAIRVVPYSAGSYPSMGGNYTLLEFKSGAYPEVAYVESRAECQYHERAAVVALYKRILQETLDIAVLMEEMQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Y4</accession>
    <name>D3Q8Y4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016164.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0882"/>
    <dbReference type="EnsemblBacteria" id="ADD40593">
        <property type="protein sequence ID" value="ADD40593"/>
        <property type="gene ID" value="Snas_0882"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0882"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_15_1_11"/>
    <dbReference type="OMA" id="NWLWINP"/>
    <dbReference type="OrthoDB" id="1746871at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048325" evidence="1">
        <location>
            <begin position="30"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="419" mass="46460" checksum="19B908B9AAA4240E" modified="2010-04-20" version="1">MKRRGFVALAAAPALAPLLASCGGSESDAKKVEIFSWWSGPGEKEGLEKLIKMYEDDNSGVKVVNNGIAGGGGSKAKDQLATRLKNQDPPDSFQGHAGAELYDYIDNKVLEDITKFIKSEKLDGVLHPEIFKGVTVDGKTYSVPVNVHRANLMWYNPKVLEEAKLEPPKSWTELIEQNKKLKKDDKITLAVGPLWTQMQLMETVLLGELKAEAYTGLWDGNTDWASSEVIDALDLFTKVLEVTDLKSASDDWQPQLDKMMKGTAAYAVMGDWVYSYLTSSKKKEYDKDYKVVVTPGSEGVFDYLADSFTLPVGAPHKANAEAWLKICGSKEGQTVFNQTKGSLPARTDIEESEFTGYLAWNYKQWKDEKTTVVGSLAHGAVVRPTWMTEIETLLGSFVDDGDSKKFADKMMSTYEKTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Z1</accession>
    <name>D3Q8Z1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LicD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0889</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0889"/>
    <dbReference type="EnsemblBacteria" id="ADD40600">
        <property type="protein sequence ID" value="ADD40600"/>
        <property type="gene ID" value="Snas_0889"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0889"/>
    <dbReference type="eggNOG" id="COG3475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_741681_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007074">
        <property type="entry name" value="LicD_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04991">
        <property type="entry name" value="LicD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="373" mass="42508" checksum="2AE0825AA1566F18" modified="2010-04-20" version="1">MTTMRESATVSAVLPEVMPETPPEREQLAASVLAEAKKVRASGDRDGAKDLLVTAIRSGLWRYARLWSELRSLMEKPEDYEPIRALWWDSPRGCHKVLPMLTTVARAASVAGEHAECRALLRKAIVLQALRGRRLRRRLGRMKHNAVKQIKARRSTPDADAFESKATVALAQLNAEFEKLGVRGFLISGTLLGLVRDGGFISWDKDIDLGFFTTEISPYDLEHAFDRSLDFNVRKIDFNTDRLRINHENGMMIDVFPHYKDEADGKIWHDGTATRWWNSPFDLTTVDFLGKPQFVPDPPERYLDENYGEWRVPNSNFDARLDAPNAQVTDQEFLNSLNYFALLAAVGKRDQVKIQRYVGLLHELGEGEWLDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9E6</accession>
    <name>D3Q9E6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2953</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018199.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2953"/>
    <dbReference type="EnsemblBacteria" id="ADD42628">
        <property type="protein sequence ID" value="ADD42628"/>
        <property type="gene ID" value="Snas_2953"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2953"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_14_1_11"/>
    <dbReference type="OMA" id="SIAWWRT"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="209"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="413" mass="43373" checksum="E68034A2390AC56D" modified="2010-04-20" version="1">MVDTPTRVRYRDVFAVREFRALWLAELLSICGDQLARVALSVMVFNSTSSATLTGLTYGLTYAPSLVGGILLTGIADRFPRRTVMAVVDLLRAALILLVVIPGMPFWGLCVLVGSVSLLNPVFKAAQLAVLPDMLPGDRFAVGMAIRQMTIQFAQLLGFAGGGLLIAVVSAHTALVADSATFLASALFVWTGLRARPAAVDTATSRPGWLSAMSRGARLAFTDRGLRTLMLLGWLMAVITVYEGLAAPYAADLGGGSAYTGLLLAADPLGGVIGAYLFGRWVPAWLRPRLVGTLAIVAAGLLGGCLLRPGLPGSLLLFVVCGGLGTIVVMQASTTFTTAVPDEHRGQVVGLSNTGLSTASGASPLLAGMIADEIGAVETVGWFGLASAALAVPLSIAWWRTYRGDRRRWTPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9G5</accession>
    <name>D3Q9G5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycerophosphoryl diester phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018218.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2973"/>
    <dbReference type="EnsemblBacteria" id="ADD42647">
        <property type="protein sequence ID" value="ADD42647"/>
        <property type="gene ID" value="Snas_2973"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2973"/>
    <dbReference type="eggNOG" id="COG0584">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030006_3_6_11"/>
    <dbReference type="OMA" id="YRMFECD"/>
    <dbReference type="OrthoDB" id="1542724at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="23"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="268" mass="29170" checksum="044DF30762EC9300" modified="2010-04-20" version="1">MRAIHFPRRRVLGPYPFLNGGRPLAFAHRGGAADGDENTPAAFARAVACGYRYLETDAHASRDGVAVLFHDHDLSRLTGDSVTIASLKWSDLRTIRLNGEPLIPRLDDTLASWPGIRFNIDTKSDAAVQPVLDAVAGAAARDRVLIGSFSDARLARVRAATSPRLATAMGTREVARLWAASRLGFAAGLLGFVPRAPAVQVPLYRGRIKVVDERFVRHAHRLGIDVHVWTVDDAQTISALLDLGVDGIMTDRLDILADVYRARGLWPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9J8</accession>
    <name>D3Q9J8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3009</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018251.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3009"/>
    <dbReference type="EnsemblBacteria" id="ADD42680">
        <property type="protein sequence ID" value="ADD42680"/>
        <property type="gene ID" value="Snas_3009"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3009"/>
    <dbReference type="HOGENOM" id="CLU_2095371_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="116" mass="12175" checksum="05663BD9146A8E3E" modified="2010-04-20" version="1">MTVQLSVAEVGAIHDEAVEIAAASGRVGNAMTKEPPDASNTGLKPGFNTLNALKAAQKRYGEKADWCAKRWSYFAVAVNDAKLALQKVDEEGADGIEHAVPFAFPATPPAGTVGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9L1</accession>
    <name>D3Q9L1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4916</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020128.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4916"/>
    <dbReference type="EnsemblBacteria" id="ADD44557">
        <property type="protein sequence ID" value="ADD44557"/>
        <property type="gene ID" value="Snas_4916"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4916"/>
    <dbReference type="eggNOG" id="COG1721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026152_2_0_11"/>
    <dbReference type="OMA" id="SDPFGMC"/>
    <dbReference type="OrthoDB" id="848990at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="DUF58" evidence="2">
        <location>
            <begin position="197"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="432" mass="46950" checksum="5EC8558608F9B896" modified="2010-04-20" version="1">MREALTNLTIRGKSLMSVGLALIVLSILLGEKDLLRVAVLVALLPFASAFVLSRTRYNIVAHRSLQPPRIAAGQQARVTLRLRNLSRIPTGSMMLEDNLPYALGSRPRLVLERLLGGGGSKVSYSVGSDFRGRYEIGPLTVRLTDPFGLVEVTRTYLVSDHLTVTPPILPLPPVRLPGEFSGRGETRARAVAVHGEDDAATREYRHGDDLRRVHWPSTAHSGELMVRREEQPWDSRATVLLDVRAAGHRGEGPTSSFEWGVSAAASIVNHLRRGGYQLRLVTEDIEVEPDPTSDGSLMDYLAGVQPHRQGSVAKLLERAGQGDTGGLLIAAIGSLSTQEAERLAGLHSSAGNRVALLIDSMSWLSLTGHARAEAEKAYQLTTATLMRGGWRVVPIRNGDNLAVRWRDLSRGRHGFAHRAAMAETVAPQGGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9T2</accession>
    <name>D3Q9T2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020199.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4991"/>
    <dbReference type="EnsemblBacteria" id="ADD44628">
        <property type="protein sequence ID" value="ADD44628"/>
        <property type="gene ID" value="Snas_4991"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4991"/>
    <dbReference type="HOGENOM" id="CLU_2669288_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="75" mass="7990" checksum="4CF298C1A6DCDB6E" modified="2010-04-20" version="1">MNFKLLAWIVLPVAGLIVAGVLVSWLIGALFSAVSWVLGLAFYLVLGAVAVGVVMWGWSKVRGKVAGAPRRKELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9T7</accession>
    <name>D3Q9T7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospho-N-acetylmuramoyl-pentapeptide-transferase</fullName>
            <ecNumber evidence="7">2.7.8.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-pentapeptide phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraY</name>
        <name evidence="8" type="ordered locus">Snas_4996</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP</text>
            <dbReference type="Rhea" id="RHEA:28386"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="EC" id="2.7.8.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.13" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4996"/>
    <dbReference type="EnsemblBacteria" id="ADD44633">
        <property type="protein sequence ID" value="ADD44633"/>
        <property type="gene ID" value="Snas_4996"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4996"/>
    <dbReference type="eggNOG" id="COG0472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023982_0_1_11"/>
    <dbReference type="OMA" id="ICSELAI"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051992">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00038">
        <property type="entry name" value="MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10555">
        <property type="entry name" value="MraY_sig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01347">
        <property type="entry name" value="MRAY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="358" mass="38057" checksum="0870248AD5673AC7" modified="2010-04-20" version="1">MLIGAIVAFVISIFITPFAIKLLRRWQQPVRNELGLASNEGKQRTPTMGGIVFVCATVIAYAVGHVSLLPLQGRPHLPTVTGLMLLGLLVGGAFIGLLDDILKVVKRHPGGLAGRYKILGQIVVGAGFGAMALYLPSPEGYTVGTGHLSLVRDLPWANITEIGALVVFVLVVMAASNSVNLTDGLDGLAAGSTAIVMAAYVVIAFWQYRHWCAEVPKLGPCYEVRDPLEVALVAGAAAGALVGFLWWNTSPAKIIMGDVGSLGLGCLIAGMAMATRTLLLLPVVCGLFVFVTSSRIIQYVSFKTTGKRVFRMSPIHHHFEMAGWSEVTIVTRFWLLAAISASLAIGVFFAEFLRAAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9U5</accession>
    <name>D3Q9U5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Malate synthase</fullName>
            <ecNumber evidence="2 7">2.3.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5004</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the malate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.9" evidence="2 7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020212.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5004"/>
    <dbReference type="EnsemblBacteria" id="ADD44641">
        <property type="protein sequence ID" value="ADD44641"/>
        <property type="gene ID" value="Snas_5004"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5004"/>
    <dbReference type="eggNOG" id="COG2225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018928_3_0_11"/>
    <dbReference type="OMA" id="CHKRGAP"/>
    <dbReference type="UniPathway" id="UPA00703">
        <property type="reaction ID" value="UER00720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00727">
        <property type="entry name" value="malate_synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1220.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044856">
        <property type="entry name" value="Malate_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011076">
        <property type="entry name" value="Malate_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006252">
        <property type="entry name" value="Malate_synthA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001465">
        <property type="entry name" value="Malate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019830">
        <property type="entry name" value="Malate_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046363">
        <property type="entry name" value="MS_N_TIM-barrel_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902">
        <property type="entry name" value="PTHR42902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01274">
        <property type="entry name" value="Malate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001363">
        <property type="entry name" value="Malate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51645">
        <property type="entry name" value="SSF51645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01344">
        <property type="entry name" value="malate_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00510">
        <property type="entry name" value="MALATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 7" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001363-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="519" mass="57660" checksum="C241BBC230C0A9A1" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9W9</accession>
    <name>D3Q9W9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyprenyl synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5028</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020236.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5028"/>
    <dbReference type="EnsemblBacteria" id="ADD44665">
        <property type="protein sequence ID" value="ADD44665"/>
        <property type="gene ID" value="Snas_5028"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5028"/>
    <dbReference type="eggNOG" id="COG0142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_2_1_11"/>
    <dbReference type="OMA" id="LELFQNW"/>
    <dbReference type="OrthoDB" id="1861068at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="357" mass="38313" checksum="F425F8AFBF73273F" modified="2010-04-20" version="1">MSTPNGHQDLQVRVERALSKFLSRQRDRLTGIDSELAPVCEAAEIFILGGGKRIRPAFAYWGFRGAGGEDGDAVVACVSALELLQASALMHDDLMDGSDTRRGEPSVHRRFALRHTSSGWSGGADDFGACAAILLGDLCMTWSDEMFTGAGMPDAAVAAARADFDWMRTEVSAGQYLDVLTQAQRDTTSARALKVARYKAAKYTIERPLLIGAALAGGSPELRSAYSAFGLPLGEAFQLRDDVLGVFGDPTQTGKPAGDDLREGKHTFLVAGAYEAADAAQLRVLDERLGDRELDDAGVAELRDIIVATGALDRTERRIDTLAEQTATALREAKALIEPRACQALTELAEAAVRRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Y1</accession>
    <name>D3Q9Y1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0983"/>
    <dbReference type="EnsemblBacteria" id="ADD40693">
        <property type="protein sequence ID" value="ADD40693"/>
        <property type="gene ID" value="Snas_0983"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0983"/>
    <dbReference type="eggNOG" id="ENOG5033H5V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139199_0_0_11"/>
    <dbReference type="OMA" id="TMEQWAT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="161" mass="17919" checksum="98331D5BEF45D284" modified="2010-04-20" version="1">MVRALSLEEYRHPLAGFSLPVPPGWERIEDPQDGVALITAEPPDGDTEFRSNAVVTVESLPFEFDLGEWQDSAETLLPQQLPNYSLIDRERLDYEGRQVIRRLAHYVTAETGSVTMEQWATIAGGTGFTLTASISTLAYDSLADVFAEMALRFRPETEVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAC1</accession>
    <name>D3QAC1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aconitate hydratase</fullName>
            <shortName evidence="10">Aconitase</shortName>
            <ecNumber evidence="10">4.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Snas_3033</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:17941"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="ChEBI" id="CHEBI:57872"/>
            <dbReference type="EC" id="4.2.1.99"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <text evidence="10">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="entry name" value="ACONITASE_2"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="12">
        <location>
            <begin position="72"/>
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    <sequence length="914" mass="97920" checksum="A05B3FDB61580CD1" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAF1</accession>
    <name>D3QAF1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="7">Glutamate N-acetyltransferase</fullName>
                <ecNumber evidence="7">2.3.1.35</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">Ornithine acetyltransferase</fullName>
                <shortName evidence="7">OATase</shortName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="7">Ornithine transacetylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="7">Amino-acid acetyltransferase</fullName>
                <ecNumber evidence="7">2.3.1.1</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">N-acetylglutamate synthase</fullName>
                <shortName evidence="7">AGSase</shortName>
            </alternativeName>
        </domain>
        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="7" type="primary">argJ</name>
        <name evidence="8" type="ordered locus">Snas_3063</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:15349"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.3.1.35"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Heterotetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ArgJ family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.35" evidence="7"/>
    <dbReference type="EC" id="2.3.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018305.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3063"/>
    <dbReference type="EnsemblBacteria" id="ADD42734">
        <property type="protein sequence ID" value="ADD42734"/>
        <property type="gene ID" value="Snas_3063"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3063"/>
    <dbReference type="eggNOG" id="COG1364">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027172_2_0_11"/>
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    <dbReference type="OrthoDB" id="1083409at2"/>
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        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:acetyl-CoA:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004358">
        <property type="term" value="F:glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103045">
        <property type="term" value="F:methione N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02152">
        <property type="entry name" value="OAT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01106">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Arg_biosynth_ArgJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042195">
        <property type="entry name" value="ArgJ_beta_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100">
        <property type="entry name" value="PTHR23100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01960">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="SSF56266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00120">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_5023459143" description="Arginine biosynthesis bifunctional protein ArgJ alpha chain" evidence="7">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023459144" description="Arginine biosynthesis bifunctional protein ArgJ beta chain" evidence="7">
        <location>
            <begin position="178"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="7">
        <location>
            <begin position="177"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="382" mass="38912" checksum="6000C242C739B057" modified="2010-04-20" version="1">MTVTVPQGFTAAGIAAGIKAGKRDLALVVNNGPQYTAAGVVTKNRIKAAPVLWTQQVIKDGKLRAVVLNSGGANACTGPAGFADTHHTAEKVAEVLDIGSADVAVCSTGLIGERLPMDAILSGVDKVAAELSATGGADAAEAIMTTDTKPKDTVVRGDGYCIGGIGKGAGMLAPGLATMLCVFTTDALIEPDIAAAALTEACRLTFDRLDSDGSMSTNDTVLLLASGASGVIPDVKGFTSELTHACGSIARQLMSDAEGSTKDVTITVTGAADTDDAVEVGRAVARDNLVKTALFGCDPNWGRILAAVGTTAAAFEPDAVDVAVNGVWICRDGAAAEDRSGVDLSGREVDITIDLRSGRDSATIWTNDLSHAYVHENSAYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAN6</accession>
    <name>D3QAN6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020253.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5045"/>
    <dbReference type="EnsemblBacteria" id="ADD44682">
        <property type="protein sequence ID" value="ADD44682"/>
        <property type="gene ID" value="Snas_5045"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5045"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_27_0_11"/>
    <dbReference type="OMA" id="LAIVECW"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="208" mass="22587" checksum="B70D9B07DB9E0FD5" modified="2010-04-20" version="1">MVEQAATGRIDKRNAVMAAAFDVFSREGYQQAHVDQIAARAKVAKATVYNHFGDKETLFRAAIEALSEAALARNLAAVARLDEAGADPGPALTDVGVRLIDCYCEEQSWALRRLLYAETPRFPDLVALVQDRVAVPVVRALADRLARLSLAGLLATDDADAAAEQFTALLTGPLEARSRYGTRRVSRAERRAVAERAVTTFLRAYSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAV9</accession>
    <name>D3QAV9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Peptidase M50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_5120</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020326.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5120"/>
    <dbReference type="EnsemblBacteria" id="ADD44755">
        <property type="protein sequence ID" value="ADD44755"/>
        <property type="gene ID" value="Snas_5120"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5120"/>
    <dbReference type="eggNOG" id="COG0750">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025778_1_2_11"/>
    <dbReference type="OMA" id="QYMVGFG"/>
    <dbReference type="OrthoDB" id="1395197at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004387">
        <property type="entry name" value="Pept_M50_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42837">
        <property type="entry name" value="PTHR42837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="102"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="10">
        <location>
            <begin position="10"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD44755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="428" mass="46760" checksum="11B01A795687C907" modified="2010-04-20" version="1">MAYVVGLVLFALGILISVSLHEAGHMGTAKMFGMRVTRFFVGFGPTMFSFRKGETEYGVKWIPLGGFVKIAGMTPQEEEEDQTPPEEQHRVFWRKPVWQRTIVLAAGSTVHFILGFLILWIMVSFVAAPNPAFANEINTSTKITVSDCLITDASRAECSDEDPEAPAKTGGLKSGDTLIKVAGKQVAGEECRVPGTSEQLDPTSWSCAINAIRALPPGKEATFTIERDGKTLTKKVAPKTVEIKGTDGKTQEVTQVGISQQNPTVPGTVTYGPVDGVGAAVTMTGDMAVKMGEAMTRIPEKIPALWNSIFGEERDKDTPVSVVGASRLGGEMVENDLWEMFFYLLITLNFFIGVFNMLPLLPMDGGHIAIAWFEKVRSWIAKKRNKPDPGRVDYMKLMPLTYTVLAIMIGFTVLTVTADIVNPITLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAX0</accession>
    <name>D3QAX0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5131</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020337.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5131"/>
    <dbReference type="EnsemblBacteria" id="ADD44766">
        <property type="protein sequence ID" value="ADD44766"/>
        <property type="gene ID" value="Snas_5131"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5131"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="EDAYLWY"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="301" mass="32535" checksum="47C9BFCC5F02DF00" modified="2010-04-20" version="1">MDAAIIAQDLRKRYGDLAAVDGVSFEVASGEFFGILGPNGAGKTTTVEIVEGLRKPDYGTVSLLGVSPWPHDRDLSRRVGVQLQATAFFERLTAREQLHTFADLYGVAASRADEMLEQVGLTEKAATRIEKLSGGQAQRLSIACALVHDPELVFLDEPTAALDPQARRNLWDLLRQVNSAGRTVVLTTHYMDEAESLCDRVAIMDHGKVLKVDTPANLVRDLNAATHISVSSGHLSAEQAAVIADGVAEVDDDGMDLRFTTHEPSAVLTALAEQSALDGLRVRGATLEDVFLELTGREYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAX6</accession>
    <name>D3QAX6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5137"/>
    <dbReference type="EnsemblBacteria" id="ADD44772">
        <property type="protein sequence ID" value="ADD44772"/>
        <property type="gene ID" value="Snas_5137"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5137"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1348255_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="30"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="22172" checksum="769E6D806E8CA51B" modified="2010-04-20" version="1">MTISKLLKCYPMRYVEYDPSPKDKQSTAEISIRVAESEADFEACAVLSNRYIREADLESSREDTQRHAAGRGNSVLIACLPDGEIVGYARVTWVGVPPKAPDNVAPPGFYLGGMAVAAEYRRRGVGRQLTVHRMKLLSRLADEAWYIVNSSNEASIDLHLEHGFHEATREFVFPGDVSDGPGTILCHAPLGPTASRCPGCPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBA9</accession>
    <name>D3QBA9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsD</name>
        <name evidence="10" type="ordered locus">Snas_1216</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="6">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016497.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1216"/>
    <dbReference type="EnsemblBacteria" id="ADD40926">
        <property type="protein sequence ID" value="ADD40926"/>
        <property type="gene ID" value="Snas_1216"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1216"/>
    <dbReference type="eggNOG" id="COG0522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092403_0_2_11"/>
    <dbReference type="OMA" id="NVVFRMG"/>
    <dbReference type="OrthoDB" id="1211060at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_S4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="PTHR11831:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S4" evidence="9">
        <location>
            <begin position="3"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="S4" evidence="8">
        <location>
            <begin position="98"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD40926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="208" mass="24033" checksum="5CCE9CEA283018BB" modified="2010-04-20" version="1">MARYTGPDCRRCRREKMKLFLKGAKCESAKCPLESRPFPPGQHGRGRPKETEYLLQLREKQKAKRTYGVLEKQFSNYYKEANRRSGKTGEELLKILESRLDNVVYRAGFAKSRDMARQLVLHGHFIVNGRKVNIPSYRVTAKDIVEVRPKSVEMTPFVVARAEAGEKKTPAWLESIPSKMKILVHNLPERQSIDTQVQEQLIVELYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBI3</accession>
    <name>D3QBI3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemopexin repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018436.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3195"/>
    <dbReference type="EnsemblBacteria" id="ADD42865">
        <property type="protein sequence ID" value="ADD42865"/>
        <property type="gene ID" value="Snas_3195"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3195"/>
    <dbReference type="eggNOG" id="COG1524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068063_0_0_11"/>
    <dbReference type="OMA" id="WVNKHNV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="262" mass="27642" checksum="3B1068487BBB2927" modified="2010-04-20" version="1">MKHKVIVFGIDGVRLDTLRTADTPNLDTITDSGFLTAVRVPDINPTISGPCWATIATGVHADEHNIHGNDLSGHRLHNHPCFLARASKAGNTSYAAAGWLPLLTDYSGGPIFKPDHQYTPPRPGGSRNGGDHISDQATTDNACRTLTDIDVDIAFVYLGQVDEVGHHQGTGAPYTAAIENADNCVGQVLDAIRSRTTYASEQWTILAVTDHGHRDGGGHGGDSDLERTAWIAGCGPGITAETGTGLGHADMPRLALTPLGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBS2</accession>
    <name>D3QBS2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mrr_cat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020382.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5176"/>
    <dbReference type="EnsemblBacteria" id="ADD44811">
        <property type="protein sequence ID" value="ADD44811"/>
        <property type="gene ID" value="Snas_5176"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5176"/>
    <dbReference type="eggNOG" id="COG4127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1106583_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Mrr_cat" evidence="2">
        <location>
            <begin position="7"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="251" mass="27334" checksum="5547B29DA9D702A4" modified="2010-04-20" version="1">MPPSISDWQEAEALASLHMRQLGLSRPHLTPPGADGGVDVLADEAAAQVKFEKSTTGKPAVQRLYGEVKRRGIHGIFYSLSGFSAPAITFANETGIALFKFNVDGLVAPVNGHAGHMAAQVRRMAPEARTASRSPWWLAPVAKGRWYFYLPILTWGFLAFVPFIHASVKSRNRRMGWLACLFGAMTFGSCVSLSIISPPADTGPPPEPAMSILMFSLLLGGIIATVLLIRIRREVYHLDGRVPETRRVTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBV0</accession>
    <name>D3QBV0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5204</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5204"/>
    <dbReference type="EnsemblBacteria" id="ADD44839">
        <property type="protein sequence ID" value="ADD44839"/>
        <property type="gene ID" value="Snas_5204"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5204"/>
    <dbReference type="HOGENOM" id="CLU_1229268_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="225" mass="23728" checksum="78AB687E9D247625" modified="2010-04-20" version="1">MGSRQHVQGLQLGQVLAQFVQQPGAAAHQRRNHVQVQLVEQPCPDELPHRVGATGDVDVPVSRDGSGLLQGTVDTVGDEGVRGAALLLDPVPAAVGQHEHRAPERWVLAPRHLAGVEHGPSHHHRAGGVEPVAHQRRVQVVLAAGQMLPFPPARQAVDRAEQLLGAVPDGIVGGAHVRPGDVTIQRDRQVGGNDRHGVLLSFDGACGQARFAGDVETAGRSSTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBZ0</accession>
    <name>D3QBZ0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M14 carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5245"/>
    <dbReference type="EnsemblBacteria" id="ADD44879">
        <property type="protein sequence ID" value="ADD44879"/>
        <property type="gene ID" value="Snas_5245"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5245"/>
    <dbReference type="eggNOG" id="COG2866">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022371_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048852" evidence="1">
        <location>
            <begin position="24"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M14" evidence="2">
        <location>
            <begin position="104"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="432" mass="45638" checksum="F11D6177774E7802" modified="2010-04-20" version="1">MATATAVALSLAVLSAASGTATADDLDTEPAYLSVPGLSGAQTRALSADGFDVVKRTADGATTVIGDAKVADRLRDRGLEPTVLDTVYKKVSTKAALGEYYGGYKTPDLHFKHLDDVAAAHPDLAKVYDIGDSWLKTQGQGGHDIKAICITKMADGDCELSPESAKPRFSVISQIHAREIATGEISWRWIDYLANGYGSDETVTSILDTTEVWVVPIVNPDGVDKVASGGDSPLLQRKNLDNSHGDCGGTQTGVDLNRNHSYGWGDAGTQPCSETFQGPSAGSEPEIVAVEEFFGKIHPDQRGDGDAPAPDDTRDVMISLHSYGEYLIVPWGHSTSPPPNDSQLRALGNAMAESNGYQVGNPSQTVGYLASGTSDDYTYGTLGIASYTFEVGGQFGECGGFLPAYSCVEDLWTLNQGALITAAQNAKAPYQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC00</accession>
    <name>D3QC00_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5255</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5255"/>
    <dbReference type="EnsemblBacteria" id="ADD44889">
        <property type="protein sequence ID" value="ADD44889"/>
        <property type="gene ID" value="Snas_5255"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5255"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_11"/>
    <dbReference type="OMA" id="QLWGYPP"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="18"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="143"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="143"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="242" mass="26803" checksum="2FFEBB72190FDB6A" modified="2010-04-20" version="1">MTSTGPKALRRPDGSPIRVLVVDDEAPLAELLSMAVRYEGWQAYTAGDGTAALKLAREHRPDAVILDIMLPDMDGLSVLDRLHADAPETPVLFLTAKDAVEDRVRGLTAGGDDYVTKPFSLEEVLARLRNLLRRSGAARANRASALTVGDLTLNEDTHEVSRAGEDIPLTATEFELLRYLMRNPRRVLSKAQILDRVWNYDFGGQANVVELYISYLRRKIDAGRPPMIHTRRGAGYILKPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTZ0</accession>
    <name>D3PTZ0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0026</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0026"/>
    <dbReference type="EnsemblBacteria" id="ADD39748">
        <property type="protein sequence ID" value="ADD39748"/>
        <property type="gene ID" value="Snas_0026"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0026"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_353324_0_0_11"/>
    <dbReference type="OMA" id="PVHHEAY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="6">
        <location>
            <begin position="528"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="492"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD39748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="823" mass="84403" checksum="B8229AAC9F1277F8" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUA0</accession>
    <name>D3PUA0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor 3</fullName>
            <shortName evidence="5">RF-3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prfC</name>
        <name evidence="8" type="ordered locus">Snas_1338</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016617.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1338"/>
    <dbReference type="EnsemblBacteria" id="ADD41046">
        <property type="protein sequence ID" value="ADD41046"/>
        <property type="gene ID" value="Snas_1338"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1338"/>
    <dbReference type="eggNOG" id="COG4108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002794_2_1_11"/>
    <dbReference type="OMA" id="GFVFKIH"/>
    <dbReference type="OrthoDB" id="164090at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006449">
        <property type="term" value="P:regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04169">
        <property type="entry name" value="RF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00072">
        <property type="entry name" value="Rel_fac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004548">
        <property type="entry name" value="PrfC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032090">
        <property type="entry name" value="RF3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038467">
        <property type="entry name" value="RF3_dom_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041732">
        <property type="entry name" value="RF3_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43556">
        <property type="entry name" value="PTHR43556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16658">
        <property type="entry name" value="RF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00503">
        <property type="entry name" value="prfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="9"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="198"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="86"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="528" mass="57392" checksum="E0D2EDD5E6BD1F03" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUE5</accession>
    <name>D3PUE5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018529.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3290"/>
    <dbReference type="EnsemblBacteria" id="ADD42958">
        <property type="protein sequence ID" value="ADD42958"/>
        <property type="gene ID" value="Snas_3290"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3290"/>
    <dbReference type="eggNOG" id="ENOG5032U97">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1718862_0_0_11"/>
    <dbReference type="OMA" id="TGVFVVC"/>
    <dbReference type="OrthoDB" id="1661001at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045674">
        <property type="entry name" value="DUF6196"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19696">
        <property type="entry name" value="DUF6196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="15479" checksum="C2BB3E297878709E" modified="2010-04-20" version="1">MVSVSVESPEQTDLRLRRVIAEAEFVVHDGVWTFAETPDPPVLTDEVLAVVRDTEVWSALVPASPELAGGERFGLFSFHFPGAPDNSGFVGWLAGHLKRELGTGVFVVCGSNTARGGIFDYWGSPAELLPQAVEVVERLRANT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUV1</accession>
    <name>D3PUV1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020546.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5341"/>
    <dbReference type="EnsemblBacteria" id="ADD44975">
        <property type="protein sequence ID" value="ADD44975"/>
        <property type="gene ID" value="Snas_5341"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5341"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_1_0_11"/>
    <dbReference type="OMA" id="FPFADRP"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="2">
        <location>
            <begin position="34"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="418" mass="44479" checksum="797861DAC03DA3C0" modified="2010-04-20" version="1">MRNGDGDNVCGGSRDGRASGASDSAPNGGARTKRVIISGAGIAGLATALRFQRAGWRTLIVEKAPGRRSSGYMVNLLGTGYDAADRLGLVPALRPNDLGVFTSMIVNPDGSQKFTIPAALTQAALGKRAITVFRGDLESALYEAVRDTAEFRFGTTVREVDQDASEVRATLSDGTVESGDLLVGADGLHSGVRELVFGPETDFRVDLRHMVGAFPLPEVPTRVPDGASATYIGPLRTAAIVNLGPGRSSAFFAYRCEDPQAELARGAFASLAERFGDLGGGFPDALRQLKADPDAAYFDSVSQIDLGSWFRGRVVLLGDAAWCVTLFAGYGAALAMTGAERLGAAITESGVDLATALEQWEAELRPEVRKRQSLARKGTAQFCPPTRFHVWMRDTTIRAIQMPGIRNLVLGSLKRATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUX6</accession>
    <name>D3PUX6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020571.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5368"/>
    <dbReference type="EnsemblBacteria" id="ADD45000">
        <property type="protein sequence ID" value="ADD45000"/>
        <property type="gene ID" value="Snas_5368"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5368"/>
    <dbReference type="eggNOG" id="COG4106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1057310_0_0_11"/>
    <dbReference type="OMA" id="VPRFAPW"/>
    <dbReference type="OrthoDB" id="1448234at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="51"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="263" mass="28659" checksum="C6155741F633AAA6" modified="2010-04-20" version="1">MPEDSERLARLARAWDDAAAGYDAYFVPRFAPWVELAVSAVVEADLPDGPILVPCCGTFPEAELLVERFPDREIAGIDLSDGMVARARERTSPWPNVTAIVGDAATLDPRWSGECAAVVSVFGLQQLPDPGLVMRSWLDALGPGGRLSVVFWPEKTETDGPFALMSEVVRGRLSAGEARPDRFAEIVTGHGAALERDEFVSYPMTHADASTFFDAFTRSGPARALALAQGDAFMDSLREEFLRLAPSGEWVHHPQARLIVAHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVD7</accession>
    <name>D3PVD7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016761.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1486"/>
    <dbReference type="EnsemblBacteria" id="ADD41190">
        <property type="protein sequence ID" value="ADD41190"/>
        <property type="gene ID" value="Snas_1486"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1486"/>
    <dbReference type="HOGENOM" id="CLU_1926278_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="139" mass="15191" checksum="48A3F3BE864AE952" modified="2010-04-20" version="1">MTDISLDKDELREFVDLMHATAREMRQIRQAQATGYAQADGNPTAAYRNGVKMTLGSVNYAHSGRLAGEIIADRIAETLEFVQSVEEGTQAMGDFVDRVLTELGAEDSIAATELARIGNDFLPPMRRRGRPSDSDTEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVK9</accession>
    <name>D3PVK9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">H+transporting two-sector ATPase C subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3459</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018694.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3459"/>
    <dbReference type="EnsemblBacteria" id="ADD43123">
        <property type="protein sequence ID" value="ADD43123"/>
        <property type="gene ID" value="Snas_3459"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3459"/>
    <dbReference type="eggNOG" id="COG0636">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148047_3_0_11"/>
    <dbReference type="OMA" id="GHIRASF"/>
    <dbReference type="OrthoDB" id="2077475at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="7">
        <location>
            <begin position="75"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="138" mass="13624" checksum="61959C3DFDA11D53" modified="2010-04-20" version="1">MIVLLAGLALVVAAVAAAYGLSRRRRRAGTVLLIAVNALLLASALLVVLLVLTGEPAQAAAPAESGDEANWAALLGAAIAVVGSSIGAAIAVAYTGSAALAALSERPELFGRAMVIVGLAEGIAIYGLIVAIILIGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVP0</accession>
    <name>D3PVP0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018725.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3491"/>
    <dbReference type="EnsemblBacteria" id="ADD43154">
        <property type="protein sequence ID" value="ADD43154"/>
        <property type="gene ID" value="Snas_3491"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3491"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="WNGTVGM"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="290" mass="31476" checksum="557061999C04FD00" modified="2010-04-20" version="1">MEFRLLQYFVAVAEERHFGRAAARLHMTQPPLSRAIKQLEADLDAVLLRRSATGVALTAAGATLYDDARALLEQVELIRTRVRAATGSTTLTIGTLADSADEAGTRLATTFRRRHPEVSIRFREADFADPTTGLRTGLVDVALTRSPFDETGISVRVLREDRVGAVLRADDPLAARDSLHLADLADRPWFQLPEGTDTMWREYWNGATPVGDRPAGPVVRTVSECVQAVLWNGTVGIAPLGHDLPEGLRLVPLADMPPSPLVVAWASASHNPLIASLVDVAVNTYRSAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVP2</accession>
    <name>D3PVP2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="2">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3493</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018727.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3493"/>
    <dbReference type="EnsemblBacteria" id="ADD43156">
        <property type="protein sequence ID" value="ADD43156"/>
        <property type="gene ID" value="Snas_3493"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3493"/>
    <dbReference type="eggNOG" id="COG1893">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031468_0_0_11"/>
    <dbReference type="OMA" id="AIWHKAG"/>
    <dbReference type="OrthoDB" id="427052at2"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApbA" evidence="3">
        <location>
            <begin position="3"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="ApbA_C" evidence="4">
        <location>
            <begin position="174"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="336" mass="35189" checksum="A9D1B5AAA73E2641" modified="2010-04-20" version="1">MKICVYGAGSIGCYVGGRLAATGADVVLIGRERLGAQLADNGLTVTDWQGAKFHVEAPRFDTTPDAASDADLVLVTVKSAATAETASTLAGLLKPGAVVISFQNGLRNAQVLRDGLPSATVLAGMVAFNVVNQGGGAFHGATEGGLEVQQDPSVSAFAEAFARAGIPLARHEDMAGVQAAKLLLNLNNAVNALCGLPLREQLSRKAYRQCLASAQREALAVFAASGIKPAKITPLPPHWIPRLLGTPDAVFARAAKRMLAIDPHARSSMWEDLEAGRVTEVDYINGEIVSLAAAHDRSAPVNQKLVELVHDAETGGRRDWPGEHLLAALRSATTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVP8</accession>
    <name>D3PVP8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018733.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3499"/>
    <dbReference type="EnsemblBacteria" id="ADD43162">
        <property type="protein sequence ID" value="ADD43162"/>
        <property type="gene ID" value="Snas_3499"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3499"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_6_0_11"/>
    <dbReference type="OMA" id="VWSHRHA"/>
    <dbReference type="OrthoDB" id="1465613at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="366" mass="38344" checksum="33D31085EA73E1FA" modified="2010-04-20" version="1">MSGVGVGVIGAGVISDTYLANMTSFPDLRVLRVADLVVEQAEAQAAKYGVPAAGSVAELLADPDIDIVVNLTIPVAHAPVSTMALEAGKHVWQEKPLALDRPSARALLDRARASGLRVACAPDTVLGAGLQTARRAIDSGRIGEPLMGLALFQSPGPESWHPNPEFLFQDGAGPLFDIGPYYVTELVQVFGPVRRVTAAGGRARDTRVIGSGPKAGTSFPVTVPTAVSALVEFERGGSAQLLLSFDSALSRAGMVEVTGVGGTAVVPDPNRFDGPTTLLVLGNPEPEVLEPQGHNATRGIGVVELARAIRAGTVERAGGELAYHVLDIMMSIDESLTRRVSVDVDSTVKVPPPLPIDWDPYERTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVU8</accession>
    <name>D3PVU8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5437</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5437"/>
    <dbReference type="EnsemblBacteria" id="ADD45069">
        <property type="protein sequence ID" value="ADD45069"/>
        <property type="gene ID" value="Snas_5437"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5437"/>
    <dbReference type="eggNOG" id="ENOG5032VBJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1026397_0_0_11"/>
    <dbReference type="OMA" id="TEWHAMA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="271" mass="30084" checksum="6B4DE30F2FABDC6C" modified="2010-04-20" version="1">MTMPALTPTARLKPARAVTRVIPRRLRHRGTNTHPEAEHALPQRLTEWHAMAPLQRAQAWSELVDWVAWLHDRYELSVANRLPACWPGHPGLIEELWALRLWRRDIYSTQDTDSGSAPNGLGQPARYWHTELHNVITRAEQFYASKCRSGHKPAATLTDHPETVREWHAADPLIGVATMPAGADPANDIDGGATVAETIMTAAFLRGTAKPVNNTAGQFAWYRGSWWAPDGPNWVSVPDSTMTAWLDNHAAHVRTTEAAVVGTPTKSTRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVX9</accession>
    <name>D3PVX9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5469</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5469"/>
    <dbReference type="EnsemblBacteria" id="ADD45100">
        <property type="protein sequence ID" value="ADD45100"/>
        <property type="gene ID" value="Snas_5469"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5469"/>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045498_2_1_11"/>
    <dbReference type="OMA" id="YAYGFIM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="264" mass="27444" checksum="951E0D32E68FBD2B" modified="2010-04-20" version="1">MVYLKNRGMETVAPAVLLALFAVALIAGSVDAIAGGGGLLTLPALLLAQIPPVHAMATNKLQSSFGTFTSAMSMRRKGLAGPVDMQAPFLFALAGSAVGTVTVQFIDTRALTVVVPVVLAGIAIYFIAMPKRPDRDVEPRLALAPYNSLVVPGIGFYDGAFGPGTGSFFTAAGVSLRGQRLVPASAQARMLNFATNVASLVVFAIGGKTMWLVGGIMAVGSMSGAYLGALAVSRGGARLIRPIVVVMCLGMLVQYLWRQGWLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVY1</accession>
    <name>D3PVY1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Competence protein ComEA helix-hairpin-helix repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5471</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020673.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5471"/>
    <dbReference type="EnsemblBacteria" id="ADD45102">
        <property type="protein sequence ID" value="ADD45102"/>
        <property type="gene ID" value="Snas_5471"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5471"/>
    <dbReference type="eggNOG" id="COG1555">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052011_1_1_11"/>
    <dbReference type="OMA" id="MVDIKGA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004509">
        <property type="entry name" value="Competence_ComEA_HhH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00426">
        <property type="entry name" value="TIGR00426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="3">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="3">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="225" mass="22820" checksum="CDD968D14A41DDB0" modified="2010-04-20" version="1">MRGRVAGLLGLTGSRFLLAGRTRGVLVMLLLIVAVTAGALTWFSWPSPQPAPGAVAVAQTNDGDGGAVGRLKVSVVGDVSEPGIVELAAGARVADAIEAAGGLTPESASPGYLNLARKVKDGELIVVEAEGENPDDPEAPAEPDPSEEPPTGETPDDPNAPGEPVNLNKATEDELATLPGIGPVTAASIVEYREQSGGFDSVDQLTEVDGIGPATLDKLADKVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW21</accession>
    <name>D3PW21_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5511</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020713.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5511"/>
    <dbReference type="EnsemblBacteria" id="ADD45142">
        <property type="protein sequence ID" value="ADD45142"/>
        <property type="gene ID" value="Snas_5511"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5511"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_2_11"/>
    <dbReference type="OMA" id="TPDWGVM"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="105"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="322" mass="34256" checksum="A91C0E55E3B242D6" modified="2010-04-20" version="1">MNGDPDPDEPKEIIGRSPGQLAWQRLKRDKTAMTAGIIVALMFIVAYGAPIIEMIYGHSPTKNNPDLLDLDSRPLGLLNGVSGDHWFGIQPNTGRDVFIRVVYGLRTSLTIAIIATIVTIALGALVGAIAGFFGRKVDAALGWITDVAMALPFLIFGLAFIPVAGTTIAGEGETPGPILVGGLLIFLFVFFGWMGSARLVRGQVISLREREFVEAARAAGAGNGHIIFKQILPNVWAPILVTFSLMVPQLVTAEAALSFLGIGIPEPTPDLGVDLGDAISVLEGDGMWFYFAVVGGTLFLMVLAFNLLGDAVRDALDPKSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW84</accession>
    <name>D3PW84_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PASTA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1538</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016812.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1538"/>
    <dbReference type="EnsemblBacteria" id="ADD41241">
        <property type="protein sequence ID" value="ADD41241"/>
        <property type="gene ID" value="Snas_1538"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1538"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_717482_0_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03793">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="3">
        <location>
            <begin position="319"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="385" mass="38549" checksum="DEA267FA1B440B4A" modified="2010-04-20" version="1">MPPAEHTTGANPGPATGRTLGDLLREHGTVAPAETMRILAEAADALDFAHSKGLAHRALTADSIRVETNGTVRLTGLAVGDGGANAETAVIDADAEFSQADADADVLALAAIGYRCLTGRMLDRAAPQPFPPQVPPVVAHPLWLSLGVQPDTRTPSATKFAQLCRGAIAGLGITTPMRPAAMSAPTPAGPPPTAALAAPKRQRQGILVAGVIAAVVLLLAGGLLVVLQPWASGNEAFAGGSKDDGGDAHSTSSADPKNSASRDDTDKSKSSKPSPSDADKDSGDGNGGGGDNGGGGDNGGGGGDDGGGGGEDDIYSGPMPDVVGMTVKQAYEAIVTEAYVQTDVNYSSSDPTCIVHTQYPSPGTHLDENSEPSITADGSAGDCGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWI1</accession>
    <name>D3PWI1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3541</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3541"/>
    <dbReference type="EnsemblBacteria" id="ADD43203">
        <property type="protein sequence ID" value="ADD43203"/>
        <property type="gene ID" value="Snas_3541"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3541"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_19_3_11"/>
    <dbReference type="OMA" id="NPAGDWE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="4"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="138" mass="15471" checksum="FF73F7004D1EB98A" modified="2010-04-20" version="1">MSEGPRFPVSVKGVCVQDGRVLLLYNERDEWELPGGKLELGEPPDVCVAREITEEAGWPVRVGGILDSWQYHIREGVDVLILTYGCYVDTTAAPVVSHEHKEAALFTLDEVAGLRMPQGYRASIRNWFAHLQGHGRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWQ1</accession>
    <name>D3PWQ1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3613</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018844.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3613"/>
    <dbReference type="EnsemblBacteria" id="ADD43273">
        <property type="protein sequence ID" value="ADD43273"/>
        <property type="gene ID" value="Snas_3613"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3613"/>
    <dbReference type="HOGENOM" id="CLU_2119617_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="114" mass="12668" checksum="17CC9B3600B70EE2" modified="2010-04-20" version="1">MHAHLPPATLVVVTSPHSAPTTTAHGLYLATHHHPEVGAYHMVCLRYQYAPPYGSRIQAYPRDEVAPTPHHLSSLDIYDMLELKTTLHHWGYPEALPTITAINNTLNHIAPLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWR6</accession>
    <name>D3PWR6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3628</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3628"/>
    <dbReference type="EnsemblBacteria" id="ADD43288">
        <property type="protein sequence ID" value="ADD43288"/>
        <property type="gene ID" value="Snas_3628"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3628"/>
    <dbReference type="HOGENOM" id="CLU_3367486_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="35" mass="3680" checksum="F172BA4B02E63FCE" modified="2010-04-20" version="1">MDSSLPALKTGTARTLATVIFDANPLTWENTGAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWW2</accession>
    <name>D3PWW2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020757.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5555"/>
    <dbReference type="EnsemblBacteria" id="ADD45186">
        <property type="protein sequence ID" value="ADD45186"/>
        <property type="gene ID" value="Snas_5555"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5555"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_11"/>
    <dbReference type="OMA" id="YIMNFAL"/>
    <dbReference type="OrthoDB" id="1209997at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048044" evidence="1">
        <location>
            <begin position="29"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="262" mass="26726" checksum="8FD837FFD43F77E1" modified="2010-04-20" version="1">MDLRLQGKTALVTGASRGIGLATAIALAAEGVTVVGASRTVSDELRDADVTVITTDLSEADAPARLVSQAIEALGGRLDIVVNNAGGGDDVTVGGLLSYDEDFWQRIFDLNFYSAVRICRAAIPALLETGGSVVNVSSMGAKIPGTPGTPVPYATAKAALNAFGKSLSEEYGPQGISVRTVSPGPTLTSIWDADKYGGGVAASAGVEHSDLMKNLPALSGMTTGRFVTAEEVGAFITYLVSPLGESIVGSDHLIEGGAIKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX45</accession>
    <name>D3PX45_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">UDP-N-acetylenolpyruvoylglucosamine reductase</fullName>
            <ecNumber evidence="17">1.3.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">UDP-N-acetylmuramate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">murB</name>
        <name evidence="19" type="ordered locus">Snas_5639</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 17">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>NADP(+) + UDP-N-acetyl-alpha-D-muramate = H(+) + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:12248"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="EC" id="1.3.1.98"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 17">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 17">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 17">Belongs to the MurB family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.98" evidence="17"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020840.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5639"/>
    <dbReference type="EnsemblBacteria" id="ADD45269">
        <property type="protein sequence ID" value="ADD45269"/>
        <property type="gene ID" value="Snas_5639"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5639"/>
    <dbReference type="eggNOG" id="COG0812">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035304_0_1_11"/>
    <dbReference type="OMA" id="MQNIGAY"/>
    <dbReference type="OrthoDB" id="841869at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008762">
        <property type="term" value="F:UDP-N-acetylmuramate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.78.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00037">
        <property type="entry name" value="MurB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003170">
        <property type="entry name" value="MurB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011601">
        <property type="entry name" value="MurB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036635">
        <property type="entry name" value="MurB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21071">
        <property type="entry name" value="PTHR21071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02873">
        <property type="entry name" value="MurB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56194">
        <property type="entry name" value="SSF56194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00179">
        <property type="entry name" value="murB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15 17" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8 17" id="KW-0132">Cell division</keyword>
    <keyword evidence="12 17" id="KW-0133">Cell shape</keyword>
    <keyword evidence="16 17" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 17" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 17" id="KW-0274">FAD</keyword>
    <keyword evidence="9 17" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 17" id="KW-0521">NADP</keyword>
    <keyword evidence="14 17 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13 17" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="18">
        <location>
            <begin position="17"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="active site" evidence="17">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="17">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <feature type="active site" evidence="17">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ADD45269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="347" mass="36640" checksum="53887E106AB2F9EC" modified="2010-04-20" version="1">MSDANLTPLATLTTLRLGGPAKRLVEAADARELVDVVRTADSANEPVLLVAGGSNLVIGDAGFDGTAVVIRSSGAEVAVDGDDVLVTVAAGHNWDSLVERAVAEGWSGIECLSGIPGSAGATPIQNVGAYGQEVAETIETVTVYDRELGETVVFTAADCRFAYRDSVFKHSDRFLVLDVRYRLRRSRRSAPIRYAETARTLGIEAGETVDATVARETVLKLRRGKGMVLDAADHDTYSAGSFFINPVVEPDVIDVIAAKAGKPPPNWPAGDKVKTSAAWLIAQAGFEKGYGHDGVSISTKHTLALTNRGDGTTAALLRLADEVRAGVEAAFGVRLRPEPTLVGTDWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXA8</accession>
    <name>D3PXA8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016942.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1669"/>
    <dbReference type="EnsemblBacteria" id="ADD41371">
        <property type="protein sequence ID" value="ADD41371"/>
        <property type="gene ID" value="Snas_1669"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1669"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_0_1_11"/>
    <dbReference type="OMA" id="PSGPNQI"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="28"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="255" mass="28128" checksum="6365083443D34258" modified="2010-04-20" version="1">MTTEDEVPAQLRRLWGLSAPAKRGRPAELDGGRVVAAAVELADREGLTGVTLAKLAKHLGYSPMSLYRYMGSMDELLELMVDAAASDTSEVEYFPDDWRTSLRSWAAAQLRQAHRHPWIHHVPITGPPSGPNQIAWLELGLRALRETGLDWPQKVGTIMLVSGYVRTFVLQMESSRRRREISGMEQAQAEAAWATHVARLIDAERFPETARLMASATFTPSDQPTSDDPAEDTDFAYGLERILDGVAVSVEAAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXD3</accession>
    <name>D3PXD3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MDMPI_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016967.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1697"/>
    <dbReference type="EnsemblBacteria" id="ADD41396">
        <property type="protein sequence ID" value="ADD41396"/>
        <property type="gene ID" value="Snas_1697"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1697"/>
    <dbReference type="eggNOG" id="ENOG50314EV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094601_0_0_11"/>
    <dbReference type="OMA" id="HITMPYR"/>
    <dbReference type="OrthoDB" id="2054078at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="1">
        <location>
            <begin position="13"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="202" mass="21856" checksum="D23B42848B8094FD" modified="2010-04-20" version="1">MGSTDPRLVEATHAERERLAHLFADLGPVQWSAPSLCHGWRNREVLAHMTMPFRLSGLGFLGGMVRARFNFNRFADRDARATADATSDAELVDLYRANIRHPWRPPGGGQAGALGHEIIHGLDITEPLRLPAPPPDRIALALGSAGPRNLAYFGVDLAGRRLVADDADCSVGIGEELRLPARDLMLVVTGRRALADVTGNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXM4</accession>
    <name>D3PXM4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3697"/>
    <dbReference type="EnsemblBacteria" id="ADD43354">
        <property type="protein sequence ID" value="ADD43354"/>
        <property type="gene ID" value="Snas_3697"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3697"/>
    <dbReference type="eggNOG" id="COG2343">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059611_0_0_11"/>
    <dbReference type="OMA" id="RYYIPRI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007361">
        <property type="entry name" value="DUF427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038694">
        <property type="entry name" value="DUF427_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04248">
        <property type="entry name" value="NTP_transf_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_9" evidence="1">
        <location>
            <begin position="37"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="NTP_transf_9" evidence="1">
        <location>
            <begin position="161"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="265" mass="30138" checksum="A17A6560C441C450" modified="2010-04-20" version="1">MLTIGGGPLSMHPPQRVNYTIDGPAHKLMMIDFPRRVRATFAGQTVLDTRAGTLLYESALLPQLYVPETDINTALLTPTDHSTHCPFKGDASYWSVSVDDRTAENAVWAYPTPNEAATWLTGYRAFYWKAMDSWHDEDEEVFGHLRDPFTRVEVVPSSRSVRVLIDDAVIAETHNPKILSETGLPNRYYLPWEDIRSDMLEHSETRTYCPYKGRSTYWSLRLGDELIPDVAWCYENPLNDAIPVLGHACFLHDRLRVEVDGQPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXV1</accession>
    <name>D3PXV1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular ligand-binding receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3774</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3774"/>
    <dbReference type="EnsemblBacteria" id="ADD43431">
        <property type="protein sequence ID" value="ADD43431"/>
        <property type="gene ID" value="Snas_3774"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3774"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_6_0_11"/>
    <dbReference type="OMA" id="MEFTGAR"/>
    <dbReference type="OrthoDB" id="776281at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049338" evidence="1">
        <location>
            <begin position="26"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="41"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="381" mass="40378" checksum="468DC4F2A364C07F" modified="2010-04-20" version="1">MTVNRRVWRVLASAAAMATVVGAMAACGNPNDSASGDCEYAIASMGALTGPNAGLGEVMRDGAKVAVEIYNEKNKDAQVCFEEFDSKGTEKDAPGVAKKIAKDKKILGVVGPGFSGESTAANPIFEEAGMPIISGSATAPELAEKGWKVFHRTIGNDAVQGPAVASYINDVLKAKKVFVIDDQTAYGEGLAKTLKDALGDKLAGEEQVKTDQKEFAPVINKLKDSKADAVFYSGYYPEGGPFLNQMKKAGVEAQFIGPDGVKDENFIEAAKDASEGAIITCPCIPGEKAEGDFAKEFEKRIGEAPGTYGAEAFDAANVFLDGIKDGVKDTKSMLDFVNKYDKAGASKHIKFDKDGNIAVDVVWAYKVEDGKIVADQEIELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXY8</accession>
    <name>D3PXY8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Low temperature requirement A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020888.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5687"/>
    <dbReference type="EnsemblBacteria" id="ADD45317">
        <property type="protein sequence ID" value="ADD45317"/>
        <property type="gene ID" value="Snas_5687"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5687"/>
    <dbReference type="eggNOG" id="COG4292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045667_0_0_11"/>
    <dbReference type="OMA" id="HMAERCA"/>
    <dbReference type="OrthoDB" id="886435at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010640">
        <property type="entry name" value="Low_temperature_requirement_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36840">
        <property type="entry name" value="PTHR36840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06772">
        <property type="entry name" value="LtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="395" mass="42598" checksum="A281294B873647D2" modified="2010-04-20" version="1">MTALGHSGQLWRRVMRPRDPDEPHRAATVLELFFDLVFVVAVAQAAVGLEHAFVEHHIGSGVVYYAMAFFAIWWAWMNFTWFASAYDVDDVPYRLLTLLQMSGALVMAAGVGDTISVHNYTVMVAGYVLMRVAMIGQWLRAAACDPARRVTALRYAGGIAVVQCFWVGWLWVPAKFQIPAFVVFALLELAVPPFAERVNVTPWHPHHIAERYGLFTIIVLGECILAATTSVQSARAAGAGGVELYLLAGAGLVIVFAMWWVYFDQPGHVMLLTSLAKALKWGYGHLLIFASVAAVGAGLQVAVAVHRGDAELGATTVGYAVAVPVAVYLLGVGVLQIFPRACWQMTVAVLVAVIAVLVAPSLLKSSIVVIAACLVVLVAVIAVLDHRLAREANPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYL4</accession>
    <name>D3PYL4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SMI1_KNR4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019018.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3791"/>
    <dbReference type="EnsemblBacteria" id="ADD43447">
        <property type="protein sequence ID" value="ADD43447"/>
        <property type="gene ID" value="Snas_3791"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3791"/>
    <dbReference type="eggNOG" id="ENOG5032X5I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1544519_0_0_11"/>
    <dbReference type="OMA" id="SHANGWP"/>
    <dbReference type="OrthoDB" id="1448907at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00860">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SSF160631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMI1_KNR4" evidence="1">
        <location>
            <begin position="40"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="181" mass="20062" checksum="131BC8D2270BD0A1" modified="2010-04-20" version="1">MMDAADTVWSVLLGQMVVAKQAIAEADPGRLEPFSPPRPKATEVEIAAFEIQTGQRLPTSYREFLSHANGWPYFYFDMDLFGLAELSGSGQHRLADELLTIYADDEVLDDIGLDHDALLPVAAGRGMRHLVAIVRTGLPDAGQVTWLDGEQVGRYPDFRAYFTAMTQFLMGQALRLRDAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYM4</accession>
    <name>D3PYM4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3801</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3801"/>
    <dbReference type="EnsemblBacteria" id="ADD43457">
        <property type="protein sequence ID" value="ADD43457"/>
        <property type="gene ID" value="Snas_3801"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3801"/>
    <dbReference type="eggNOG" id="COG3063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="ACAVQWA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="993" mass="106562" checksum="F68CCEC2C0E6880A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYM8</accession>
    <name>D3PYM8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3805"/>
    <dbReference type="EnsemblBacteria" id="ADD43461">
        <property type="protein sequence ID" value="ADD43461"/>
        <property type="gene ID" value="Snas_3805"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3805"/>
    <dbReference type="HOGENOM" id="CLU_1721235_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="152" mass="17302" checksum="5EC81DB09F88D49A" modified="2010-04-20" version="1">MANDYGDHVSPDPADENNGRPEPDHDDEQALARHRAAVEADLSKANETLDRVRREMPYRKALWGYRLYYIGILSSVGSLIAGCVGENSAPMVVIPIALPLGILGYVYGYFQLRREYHAYMSAASAEVWHSRRDRKNLWQSSIFRDAFMGRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYN2</accession>
    <name>D3PYN2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3809</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43465">
        <property type="protein sequence ID" value="ADD43465"/>
        <property type="gene ID" value="Snas_3809"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3809"/>
    <dbReference type="HOGENOM" id="CLU_1766899_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="147" mass="15070" checksum="AA08691761B6E390" modified="2010-04-20" version="1">MIGIIIAVVAVLILAVGIGGFFLIRGAANDSADGGDESTTSESSSSSSEETTSALPSETSDDTGNFADAAQAGDCLDYPTDPNDTKVVDCGDSSAYYEVLERVDSPSTTENTDEAAAAECEGTSFDSTLYLLGSDVADPFVLCLKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYY4</accession>
    <name>D3PYY4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nuclear export factor GLE1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5783</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5783"/>
    <dbReference type="EnsemblBacteria" id="ADD45413">
        <property type="protein sequence ID" value="ADD45413"/>
        <property type="gene ID" value="Snas_5783"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5783"/>
    <dbReference type="eggNOG" id="COG4549">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087540_0_0_11"/>
    <dbReference type="OMA" id="NKEVVRW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08545">
        <property type="entry name" value="YcnI_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012533">
        <property type="entry name" value="YcnI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038507">
        <property type="entry name" value="YcnI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07987">
        <property type="entry name" value="DUF1775"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049376" evidence="3">
        <location>
            <begin position="30"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1775" evidence="4">
        <location>
            <begin position="35"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="254" mass="26609" checksum="254DFD82A2EF1A13" modified="2010-04-20" version="1">MMKGISMNPMVRRAATILAASALGVLAFAAPASAHVTIAPVEAEAGSYARLDFRVPNESDEASTIEVEVNLPKETPLASVRTKKIDGWKVETKTRKLDKPIDLHGRKVKEAIGTIIWTADSDKTGIQPGEFGEFPITAGPLPDKGTLVFKTIQTYSDKSKSEWIDEPNEDGSEPEEPAPTLKITPAKGGGHHGGTTTGDDDDADDADDHADDEDEAAGSGTTILAAVGTGLAAIALVVAVLAFLARQRGSAAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ16</accession>
    <name>D3PZ16_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide TPR_4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5815"/>
    <dbReference type="EnsemblBacteria" id="ADD45445">
        <property type="protein sequence ID" value="ADD45445"/>
        <property type="gene ID" value="Snas_5815"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5815"/>
    <dbReference type="eggNOG" id="COG0790">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1077320_0_0_11"/>
    <dbReference type="OMA" id="HEEARTG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="258" mass="28445" checksum="BFD194CCDE7DAEEC" modified="2010-04-20" version="1">MATLDAPYVLESLMDHTGPLREDFEAAREGDSNSMFNLGLAFARIGQIDDAVHWYTRAAEHGDNDAVANLGLLLRDQERYDEAEKWLRHGAEAGHAMSANNLGNLLLGWLRFDEALFWAERAVELGSTAAAGNLERVRLLARYHVPDTEPNREFARGMELVEKADVDAALPHLGAAAAQAHPDAAFELASLLAARDERDDAAGWYRIATMLGNPRAMVRLVMVCLRQGNRDEARRWAEKAVESGETLAGPLLEALDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ45</accession>
    <name>D3PZ45_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5845</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5845"/>
    <dbReference type="EnsemblBacteria" id="ADD45474">
        <property type="protein sequence ID" value="ADD45474"/>
        <property type="gene ID" value="Snas_5845"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5845"/>
    <dbReference type="HOGENOM" id="CLU_080168_4_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070273">
        <property type="term" value="F:phosphatidylinositol-4-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008628">
        <property type="entry name" value="GPP34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038261">
        <property type="entry name" value="GPP34-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05719">
        <property type="entry name" value="GPP34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="215" mass="23249" checksum="DF0FBC06C68016E3" modified="2010-04-20" version="1">MTTLAEAMILLSDRGSSARFTTVDRNSATVGATLADLALAGRIALHGKDVTVVDPQPTGDAVMDEVLAQIAASKPRQPAKWMSRLYWGFPNRVRDALAGREVLTRTTSKLFHVRKYTSATPAAETETRQRLLAAVATGGTDDAWVAELAAQVRAANMEQYLLPELPRAEARQRIAAIAASSWTGEASRAARHNNYIAYTAALLPIAVTLMIVFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ56</accession>
    <name>D3PZ56_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5856"/>
    <dbReference type="EnsemblBacteria" id="ADD45485">
        <property type="protein sequence ID" value="ADD45485"/>
        <property type="gene ID" value="Snas_5856"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5856"/>
    <dbReference type="eggNOG" id="ENOG502ZBU7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035969_1_0_11"/>
    <dbReference type="OMA" id="PEPSHLW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021391">
        <property type="entry name" value="DUF3027"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11228">
        <property type="entry name" value="DUF3027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="492" mass="51961" checksum="8F1B4DDF12EBD922" modified="2010-04-20" version="1">MNDASTLLVFDTGPVTAMRDCDGTCWPRAVTASYPCRVSQIPTMSRPARLDRLCAEAVELARAAAEETGEGVGEYLHAEPEAERVVTHFFETTLAGYRGWRWAVVVARAPRSRTVTVNETALLPGPDALKSPEWVPWAERLRAGDVGVGDLLPTDESDARLTPAYTYSDDDAVEDIAFELGVGRARVMSREGRIDCAERWYEGDHGPSAEISVSAPPEARCGSCGFYLPLAGSLRQVFGVCGNMYASDDATVVSSDHGCGAHSEVLTQIDATGPRDVELTDTAYDDALIEQVDTTADDEEPEAPVAEVEEADEADEADATAEVEAETETAEVEVEVTETAEAEPETTVTEPAPEPTAVEVAEAPADTPETTEIDAVEAPAVEAPQPVETEPVAEAQPAAEPVAEAEPEVAVVEPMTEADQVADTPEGGVTEPIAEPLAVTEVAAPADVETPAEAEVTEAEQPQATQDDSGKDEEPNDASPAGDVSGSDREAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ57</accession>
    <name>D3PZ57_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Futalosine hydrolase</fullName>
            <shortName evidence="1">FL hydrolase</shortName>
            <ecNumber evidence="1">3.2.2.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Futalosine nucleosidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Menaquinone biosynthetic enzyme MqnB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mqnB</name>
        <name evidence="3" type="ordered locus">Snas_5857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>futalosine + H2O = dehypoxanthine futalosine + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:25904"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:58863"/>
            <dbReference type="ChEBI" id="CHEBI:58864"/>
            <dbReference type="EC" id="3.2.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.26" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021057.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5857"/>
    <dbReference type="EnsemblBacteria" id="ADD45486">
        <property type="protein sequence ID" value="ADD45486"/>
        <property type="gene ID" value="Snas_5857"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5857"/>
    <dbReference type="eggNOG" id="COG0775">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031248_3_0_11"/>
    <dbReference type="OMA" id="MEGYGVA"/>
    <dbReference type="OrthoDB" id="1860206at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00991">
        <property type="entry name" value="MqnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019963">
        <property type="entry name" value="FL_hydrolase_MqnB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03664">
        <property type="entry name" value="fut_nucase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="2">
        <location>
            <begin position="28"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="204" mass="20465" checksum="16B55DA759E1B38F" modified="2010-04-20" version="1">MKLLIVTAVDAERDAVLRGLSGTVHDVYTVGVGPAAAAAGTARLLALAEAAGTRYDGVVNAGIAGGLAGRADIGDVVVGTASISAELGVRTDDGFTPLGKLGFGSAVAECSLRLAAGVTGARGEILTLATITGSAQRVDELAESYPHALAEAMEGFGAATAAARVRLPFTEIRAISNAVGDRDASGWNWQAAFDALTKAAGELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZJ2</accession>
    <name>D3PZJ2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="9">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gltX</name>
        <name evidence="13" type="ordered locus">Snas_1970</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017237.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1970"/>
    <dbReference type="EnsemblBacteria" id="ADD41666">
        <property type="protein sequence ID" value="ADD41666"/>
        <property type="gene ID" value="Snas_1970"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1970"/>
    <dbReference type="eggNOG" id="COG0008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015768_6_1_11"/>
    <dbReference type="OMA" id="HYINTLP"/>
    <dbReference type="OrthoDB" id="1409413at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020752">
        <property type="entry name" value="Glu-tRNA-synth_I_codon-bd_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020061">
        <property type="entry name" value="Glu_tRNA_lig_a-bdl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="SSF48163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="11">
        <location>
            <begin position="3"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_2" evidence="12">
        <location>
            <begin position="339"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="254"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD41666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="492" mass="55081" checksum="1C2531BBB92803F6" modified="2010-04-20" version="1">MTEVRTRFCPSPTGVPHVGLVRTYLFSWAYARHHGGQFVFRIEDTDAARDSEESYHQLVDALSWMGLDWDEGVEKGGPHGPYRQSERTEIYADVMKRLLDGGYVYEAFSTPDEVEARHRAAGRDPKLGYDNFDRTLTQEQKDTYRAEGRKPVLRLRMPDTPITFTDGVRGEITYEPGNIPDFVIARADGSPLYTLTNPVDDAMMRITHIIRGEDLLSSTPRQIALYRALVDLGVAERVPQFAHAPLVVDESRKKMSKRDPRMDLLAYRDKGYLPEGIINYVGTLGWSIAADRDVFTLDEMVAAFDLADVNSSPARFDEKKLDAINAHHIRQLAPEDLAKRLIPVLQKLNLLPDEPTAEQLRVLAVATPLVQERTGTLVQGAEMLRFLYAGEDFALDEASATKTLKGDAGTVLDASIEVLSKLDDWSTEAIETALKTKLIDELEIKPRKAFAPVRVAATGKTVSPPLYESLELLGREVSLDRLRAARERVAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q013</accession>
    <name>D3Q013_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5914"/>
    <dbReference type="EnsemblBacteria" id="ADD45542">
        <property type="protein sequence ID" value="ADD45542"/>
        <property type="gene ID" value="Snas_5914"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5914"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_11_8_11"/>
    <dbReference type="OMA" id="PVACGGW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="167" mass="18091" checksum="51D5C17A89CD43F1" modified="2010-04-20" version="1">MRPEFRLESYDSEVVRHLNTAVQREYHRRYGGGDETVLAAADFVPPNGAFFVAYLDGEPVASGAWRSHGESDAEMKRLYVVDTARGLGLARSMVALLEENAAAAGRARMILETGTEQPEALALYASLGYAPVEPFGFYANEEGARHLGKALSGHNPHLTHKTGTTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q022</accession>
    <name>D3Q022_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021122.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5923"/>
    <dbReference type="EnsemblBacteria" id="ADD45551">
        <property type="protein sequence ID" value="ADD45551"/>
        <property type="gene ID" value="Snas_5923"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5923"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108054_2_1_11"/>
    <dbReference type="OMA" id="VTWAGLM"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="16"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="136" mass="15285" checksum="F1F2CB839A6D0C53" modified="2010-04-20" version="1">MRGRAKFDPDIPRKKRHDYWGIVIEAPDAHALARFYAELLGWEIASQSEDGAALLPFDGVGYLGIQQADDYVAPAWPTREGEQQMMMHLDFEVTDLNAAVAHARELGAVEADFQPQDNVRVMLDPAGHPFCLYQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0C5</accession>
    <name>D3Q0C5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015360.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0067"/>
    <dbReference type="EnsemblBacteria" id="ADD39789">
        <property type="protein sequence ID" value="ADD39789"/>
        <property type="gene ID" value="Snas_0067"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0067"/>
    <dbReference type="eggNOG" id="ENOG5034AYS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_518657_0_0_11"/>
    <dbReference type="OMA" id="EETWQQG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038332">
        <property type="entry name" value="PPE_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="485" mass="51271" checksum="4C8D69DA8595A935" modified="2010-04-20" version="1">MGEFDAYDIDELAEMVSRDRPGGLFDQAAGWRKLHRLLDGYATRLSERLDQARPSWAGAAADVYFAELRARHDELRWASDTADFNASAWDRIASNAARSQGEVLRIQQEWRDVDGSEPTDGTESRLREERRRSYDEAARAVMDEVSGDNDLSRAAMADHHQFTPMPGVDLPEDHPVEPRDPGEPRGPVNPRDPRDPVNPPSGRGPELQGPGGAPPAPQPASVLPPDPGPAPGPRPVPVPTPTPVPGPRPTPVPRPGPGSGPGPKPTPAPRPGLGPRPTPTPAPRPGVTPRPVPGTRPTPRPPGPTVRPVIGSRPGTNVPGPGTRVPGSLTRPVIGSRPAVGGTEAPKALIGKDGVAGRRGTGATPGVRSSTSHFGGGGLNRPVVGSSRAKPASGAAPGPGGRVGRRRGDDETNHGDGPLGEFWTPGRTVPSVITSRPTVEHDPGPVSQLGRRRPRAETTPDEETLWSPPMSHQEGLSRKDAERWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0G9</accession>
    <name>D3Q0G9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017276.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41705">
        <property type="protein sequence ID" value="ADD41705"/>
        <property type="gene ID" value="Snas_2010"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2010"/>
    <dbReference type="eggNOG" id="COG5563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_737521_0_0_11"/>
    <dbReference type="OrthoDB" id="816743at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049605" evidence="1">
        <location>
            <begin position="36"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="354" mass="37439" checksum="2A8000C25E09579D" modified="2010-04-20" version="1">MPKWWTKRVRLTASAAVVVATISAAVITLVVTGDADSEADGVKVIRPEGAASCEVVKLDSPDSGSPVLPEGVSPEGEYIIGDATGASGLPGLWRDGKPIRFTGLDKSLSHEVSDVTDSGAVVGTTTSGGEDESVLGWRWEDDRVRELSENWATPTAIDEGGTIIGERSDGELVKWDEAKGKTSTITLEVDDDMYATLNDVSEDGVMVGRQEDGGSEGEFDPYQQARIWDGKGKGRNVPLDGSVRSQVVDISGDWVLIRHDQGEFRWNITGEDRPEKLDGILAQAIDGSGNVYGTLERGKDSLPGLYDGELRPLPVLGGVDEHGPASDSAVSAVSADGSVLAGDWKGNPVMWSCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0L0</accession>
    <name>D3Q0L0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Branched-chain amino acid transport</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017317.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2052"/>
    <dbReference type="EnsemblBacteria" id="ADD41746">
        <property type="protein sequence ID" value="ADD41746"/>
        <property type="gene ID" value="Snas_2052"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2052"/>
    <dbReference type="eggNOG" id="ENOG5032T1U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159912_0_0_11"/>
    <dbReference type="OMA" id="WRRAPFV"/>
    <dbReference type="OrthoDB" id="1965661at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008407">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_AzlD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05437">
        <property type="entry name" value="AzlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="102" mass="10636" checksum="710E31D95DC6F07E" modified="2010-04-20" version="1">MTWTTILVLAAGTYAFRIAGPLLRKRITVSKAAEEWMKRGATVLLVGLIATAAVYEGGQFADWALPAGVVVGGVLAWRKAPFVVVVIAAATTAAAIRLVVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0M0</accession>
    <name>D3Q0M0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2062"/>
    <dbReference type="EnsemblBacteria" id="ADD41756">
        <property type="protein sequence ID" value="ADD41756"/>
        <property type="gene ID" value="Snas_2062"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2062"/>
    <dbReference type="HOGENOM" id="CLU_132127_0_0_11"/>
    <dbReference type="OMA" id="TDQRVTP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045713">
        <property type="entry name" value="DUF6069"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19545">
        <property type="entry name" value="DUF6069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="138" mass="14379" checksum="EE74CA6AC244A9F3" modified="2010-04-20" version="1">MNTETVTATPVPANRRRVWILSIVAAVSLPTALWTIVDPLAGHELVAASGGQTMHVTLPWVIAGAMAPGMIGLGLSMVLRRLTKHSRIVWLIVSILALAGSLGSPLGGTTTTTVLVLMTMHLMVGAAIIPGGLKLTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0U1</accession>
    <name>D3Q0U1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4039</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019262.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4039"/>
    <dbReference type="EnsemblBacteria" id="ADD43691">
        <property type="protein sequence ID" value="ADD43691"/>
        <property type="gene ID" value="Snas_4039"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4039"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033532_0_1_11"/>
    <dbReference type="OMA" id="EGMTWAL"/>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="212"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="409" mass="41628" checksum="82C7D5CC31C9CEF8" modified="2010-04-20" version="1">MLKPYREIFAAPGSLRFSLAGFVARMPQSMLPIGLVAMLSELRGQYGLAGAVSATFTLSMALLSPLVSRLVDRHGQRRILVPAMAVSAASITGVLLSAHFGAPAWTLFAFAVPAGTLPTMSAMVRARWTEIYRGSDAMTTTHSFESVVDELTYVTGPAVSILLSTAVFPQAGPLLAIVLLVAGVAAFAVQRRTEPAPRPAETGGGSAIRRAPLRLLVFVLFAGGVVVGTVDVVSVAFAEQQGITAAAGIVATCYALGSGIAGLAFGAWKPRIALPKQLVIGAAGTAATTLPFLLAADIASLSAAVFVAGAFFAPTMIIVMSLIEKLVPPAQLTEGLTWAATGVSIGMAAGAGASGFVVDAFGATTGFTVALCGGVLALAAATVGLRMLTRALRSRPGATERMPVTSAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1D9</accession>
    <name>D3Q1D9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ErfK/YbiS/YcfS/YnhG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_6095</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2015-05" db="PDB data bank">
            <title>Crystal structures of L,D-transpeptidases (Yku).</title>
            <authorList>
                <person name="Chang C."/>
                <person name="Bigelow L."/>
                <person name="Clancy S."/>
                <person name="Joachimiak A."/>
            </authorList>
        </citation>
        <scope>X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS) OF 61-303</scope>
        <scope>DISULFIDE BONDS</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PDB" id="5BMQ">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="2.05 A"/>
        <property type="chains" value="A=61-303"/>
    </dbReference>
    <dbReference type="PDBsum" id="5BMQ"/>
    <dbReference type="SMR" id="D3Q1D9"/>
    <dbReference type="STRING" id="446470.Snas_6095"/>
    <dbReference type="EnsemblBacteria" id="ADD45719">
        <property type="protein sequence ID" value="ADD45719"/>
        <property type="gene ID" value="Snas_6095"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6095"/>
    <dbReference type="eggNOG" id="COG1376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056729_1_0_11"/>
    <dbReference type="OMA" id="YNTPMPY"/>
    <dbReference type="OrthoDB" id="975147at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword evidence="8" id="KW-0002">3D-structure</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="5">
        <location>
            <begin position="186"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="72"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="107"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <evidence type="ECO:0007829" key="8">
        <source>
            <dbReference type="PDB" id="5BMQ"/>
        </source>
    </evidence>
    <sequence length="303" mass="33256" checksum="2B47FFEEAD164AF5" modified="2010-04-20" version="1">MTTTSVGVGSNVLFIESVEKVVAMLLWEAKLNSEALRRGRAFLMFAIAAVALVALSNGFLAYASDGSDQADLVSATEEAKDEKSEEPTPSETPTETETATPTTDHDCGKAGEYQKDLETTLASLADYGTIFADGKQSKEDCAAIKKFQKRMGIQPAEGYAGKLTLDVAQRIAKSSFDKCQEAKKGKTVCVDLTHQTLWVVEDGKRIFEPTVVRTGMAGYATQPGAWKIFVKEGTHWSKKYKVWLPYWQNFNNGEGLHTTTTYIHEPWIGSHGCVNLLPSDSKKLYEMLDFGDTVQVFGNRPGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1E4</accession>
    <name>D3Q1E4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_6100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021295.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6100"/>
    <dbReference type="EnsemblBacteria" id="ADD45724">
        <property type="protein sequence ID" value="ADD45724"/>
        <property type="gene ID" value="Snas_6100"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6100"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_46_8_11"/>
    <dbReference type="OMA" id="HWLLLTY"/>
    <dbReference type="OrthoDB" id="1121832at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="21"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="482" mass="51033" checksum="55DD3C2FE7AE9FD3" modified="2010-04-20" version="1">MASPTGIAGSFRQLSAPQRKAFFAAWLGYLLDGFDFILITLVLTEIADEFDLGLTAAATLVSAAFVSRWLGGLLLGSIGDRFGRKPAMIISILAFSVGSLLCGLAWGYWSLFVFRAIVGLGMAGEYGSSATYVMESWPKSMRNRATGFLLSAYPIGTVVAALAYQVIVPLGGWRWLFFAGLLPIALTLYLRRALPEAAEWQAEVGDRADKDVATSSVLFTPRRRLPNALLATVLAAALVLLFSENTGGFGWLLIAVTVAGFVAFTVQVAGRLWPVMLAIMVTVFSAFLYSWPIQSLLPTYLKTELHYTAGQVSTALTWAGLGYAAGCCLAGVVADRLGTRVTYVGGLFISLLFVVPVFILPAGNIVLLWILLFVMQATSQGISGLLPKYIGDHFPTRLRAAGLGFSYNVGALGGALAPLAGAAIAAEMDSLGHALMILAGSLTVLVALIIGFDIPARIGRALKTDSEAPAFAKPEGTLTSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1G7</accession>
    <name>D3Q1G7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6123</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6123"/>
    <dbReference type="EnsemblBacteria" id="ADD45747">
        <property type="protein sequence ID" value="ADD45747"/>
        <property type="gene ID" value="Snas_6123"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6123"/>
    <dbReference type="HOGENOM" id="CLU_2994515_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="57" mass="6444" checksum="92A0DA5A2F7C478C" modified="2010-04-20" version="1">MNTIYRNAFDNGEDYGPHGPNAWNGKTCAHCTAEKGHTVEWPCSPARKLRERDRGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1J2</accession>
    <name>D3Q1J2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0119</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0119"/>
    <dbReference type="EnsemblBacteria" id="ADD39840">
        <property type="protein sequence ID" value="ADD39840"/>
        <property type="gene ID" value="Snas_0119"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0119"/>
    <dbReference type="eggNOG" id="COG0815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040924_0_0_11"/>
    <dbReference type="OMA" id="WPENEFA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045378">
        <property type="entry name" value="LNT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20154">
        <property type="entry name" value="LNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="454"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="3">
        <location>
            <begin position="221"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD39840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="505" mass="52545" checksum="3E0DEA55FB03159F" modified="2010-04-20" version="1">MDAVRKTPLWIVVVATAASAVLLYSGTGIYAVAALTWLAPVPVLWLAPRVSARAAFLTSAVAGLVGATNNLIWYITSPSDAPLWPMGLMIMLAYSLTFALGVLPYRALLLRGRALLAAVTLPAVWTVVLWIVAVSNPTGIMGTLASAQGDVPLVLQTTTVTGMWGLEFLVLFVPAGIAALFAPSVGAGARWRTAGVAVVVAGLVLGLGAWRLVGGGEGPSQTVALLSNNDSGWGARLDQPAGEELVAKYEKRIAALPDGVEAVVLPEGEFTADEESLGVLVEPMRRLAKEKDLTIVVGAVYKDEPKQYNNALVIPPKGDVVTYTKHHDGGPNTLGTELAFQPGHGKRVGIAICADLNIPNPARQYGVAGARALLVPAADERYDGWLHARAGVLQTVANGSSMAWAGRTGTLTVTDGYGRVLAEKDSGGAGEFTEVVTEVPQGPGATVYSRYGDWFVWLCIGLAAVGTVLALSKRRDKPSPAASATVEAAAAASGRPTEPVRSGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1K1</accession>
    <name>D3Q1K1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0128</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015420.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0128"/>
    <dbReference type="EnsemblBacteria" id="ADD39849">
        <property type="protein sequence ID" value="ADD39849"/>
        <property type="gene ID" value="Snas_0128"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0128"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_1_0_11"/>
    <dbReference type="OMA" id="GQMQERT"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="163" mass="17325" checksum="2E710E82B6D7A5A0" modified="2010-04-20" version="1">MAGETVITVVGNLTDDPELRYTPSGAAVAKFRVASTPRTFDKASGEWKDGEALFLSCNAWRQLAENCAETLSRGSRVVVQGRLRQRSYETREGEKRTVFELEVDEIGPSLKYATAKVQKVSRGAGGGGGRSGGGSAPDDPWATAVPAGSSGQQRGGFDEEPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1M5</accession>
    <name>D3Q1M5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_0153</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0153"/>
    <dbReference type="EnsemblBacteria" id="ADD39873">
        <property type="protein sequence ID" value="ADD39873"/>
        <property type="gene ID" value="Snas_0153"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0153"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_3_11"/>
    <dbReference type="OMA" id="WITERHG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="102"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="170"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD39873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="398" mass="42552" checksum="D68CAACF6BCAAE66" modified="2010-04-20" version="1">MRWPRFTARGRLTLLYMAMVLGAGAVMTALTYVLMRSSLRRRSFVHTDVDPDSPAGLPFPERFDELIERDRMTILSDLLVKATVALVVVSVLAAVLGWFVAGRVLRPIRQISAASRRLSAENLAERVPVRGPADELAELADTVNGMLDRIQRGVAERDRALASQRLFTANAAHELRTPLTTMRTAIDVTLDGEPDRDELLAMIADLDTTVERSRRTLDGLLLLAGSHAAPAEQSPVALDGLVAELLEAKAPAIAEHRIDVRRELFPAPALGDPLLLERLTGNLIDNAVRYNHPDGHIALRTGTADGRAFLRVANSGPHVAPESAPGLLEPFVRGGGGRIRATGGVGLGLSIVRAVVTAHDGDLSIAANPDGGLTVTVELAVDPAAATRTDGGRDDHVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1S8</accession>
    <name>D3Q1S8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0207</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015497.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0207"/>
    <dbReference type="EnsemblBacteria" id="ADD39926">
        <property type="protein sequence ID" value="ADD39926"/>
        <property type="gene ID" value="Snas_0207"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0207"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_101_2_11"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="68"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="68"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="180" mass="19639" checksum="66A7B9F41CE6D342" modified="2010-04-20" version="1">MSTSTITHARPPRPARRLAVTVEFPRGTDGLGDQMLSVLATLKELVGQGGTVTVASDPPQAPVPLLPKKSHAAAPPDGGIRVFPETRIVTDGPRPVPLSRLEFDLLHFLIARPDRVHTRQQLLEVVWGVGRGDIGQRTVDVHVRRLRAKMPRLAEALVTVRGVGYRFDSTDTVALISIRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1V9</accession>
    <name>D3Q1V9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_2132</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017397.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2132"/>
    <dbReference type="EnsemblBacteria" id="ADD41826">
        <property type="protein sequence ID" value="ADD41826"/>
        <property type="gene ID" value="Snas_2132"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2132"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="IAPERMS"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03793">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00740">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51178">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="28"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="10">
        <location>
            <begin position="425"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="359"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="366"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="398"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="426"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD41826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="499" mass="52490" checksum="88E87796158F1778" modified="2010-04-20" version="1">MPTPDETPIGREPTRESLPPTAIVSDRYRLDHRIGSGGMGEVWSGLDTRLERPVAVKLMHHELSGNKRFRARFASEAKLVAALDSPHVATLYDYGEEATPGGPRSYLVMEMVRGGSLADLLDTRDTLAPGETMKIIAQAAEGLQAAHDAGIIHRDVKPGNILVTGDRHVKLIDFGIARAKGEARLTKSGEAVLGTLAYTSPEQLNGDEPTPSVDVYSLGVVAYECLAGRPPFASDNPGAVLKGHLYQQPPPLPDNVPAPVAEAVMRALDKDPEQRWTSTAAFAQACRDAVEAPEPLPVKVSAPVGGPESEATTVPLGPTGPVPSSGTRRIGFGRVAAVLAAVVLLVAVAVLWRPWTYFGEAPGHDGSKEAATKDVADSSDGKSDKSSEKDKTKNSASSKSEAAEGGQSSDSGGNDSSSGGDDGNGNERVEVPDLEGRTHTEAPNVLESHGFDNYKGVAQPWNPGDQACVVTSQVPVAGAKVDPDTKINFYFKGGEGICQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2G2</accession>
    <name>D3Q2G2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019466.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43895">
        <property type="protein sequence ID" value="ADD43895"/>
        <property type="gene ID" value="Snas_4246"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4246"/>
    <dbReference type="eggNOG" id="ENOG502ZK00">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1115233_0_0_11"/>
    <dbReference type="OrthoDB" id="2192208at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="249" mass="26632" checksum="6AE2F41A0FDE3A3A" modified="2010-04-20" version="1">MRHPNANTSARTVFLAIGKWTALVAAAFLTAKGEHELALLIGIHDPYAWLFPVALDVYAAVAFATHANREANIALALMVVCQSITHIQSAGPDNLWSVVLTVAVSAVPPIICQRVHHLGTNTSDETKPAPQPAAKTVDPEPVAVTVPALTAHPLPWPTARAETVLAEIAAATQTTTNPAATTGTTRRPAKRAPRKTREQRLADLRAIITARPTVDQTDAARHMGVSERYVRNLFPGSWDDFRATVAATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2J7</accession>
    <name>D3Q2J7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4281</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019501.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4281"/>
    <dbReference type="EnsemblBacteria" id="ADD43930">
        <property type="protein sequence ID" value="ADD43930"/>
        <property type="gene ID" value="Snas_4281"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4281"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040011_1_1_11"/>
    <dbReference type="OMA" id="WAWLTRF"/>
    <dbReference type="OrthoDB" id="1345431at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="234"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="423" mass="43731" checksum="A94EEFF23A5FC651" modified="2010-04-20" version="1">MTTGTAGPPSALTEPRDKVGPGWIGGITAGVLGIYMAFFTPIQILLPIQLAAIDPGSKVETFGLVTGAGALVAVIANPLAGALSDRTTSRFGRRHPWTLGGVVLGAAALIALGYQTSVLGVLIGWCAAQAALNAAYASINAAVPDHVPVRQRAVVSGWIGFPQALGLVLGAIVVTMLVTGAEAGYLAIALAAVALALPFVLTTADPPLSRAHRPTVSWRRILAGFWVSPREHPDFAWAWITRFLVMLGNSTGTLYLLFFLQDAVGYERLFPGHSSDEGVLILTLIYTAGVMATAVVSGVVSDRIGRRKSLVTASAAVIAFAALLLTFWHTWPMSMIAAGVMGAGFGVYLSVDQALITQVLPAAADRAKDLGVINIANSAPQVLGPALAAPIVAGLGGYTGLYALTAAITLLGGVLVWKIRSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q301</accession>
    <name>D3Q301_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015542.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0253"/>
    <dbReference type="EnsemblBacteria" id="ADD39971">
        <property type="protein sequence ID" value="ADD39971"/>
        <property type="gene ID" value="Snas_0253"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0253"/>
    <dbReference type="eggNOG" id="COG1335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066901_1_2_11"/>
    <dbReference type="OMA" id="SNDRMRD"/>
    <dbReference type="OrthoDB" id="1860541at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="204" mass="21149" checksum="40C8952BCDC6D2DE" modified="2010-04-20" version="1">MTPEVLTADNTAVLLVDHQIGLFTGVRDLGTDELAHNVAALAASATRLGLPVIATTTAADSMWGPLVPELVAALPHGHPVIDRGTVNAWDDERVRRAVEATGRRNLVIAGVSLEVCAALPALAAVRNGLNAYVAVDASGTFSRTKRETGLLRLAQAGVVVADYSALMVEILADNAAPHAGEVYGALDMPFAKLVGGLSAAIRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3H7</accession>
    <name>D3Q3H7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2331</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2331"/>
    <dbReference type="EnsemblBacteria" id="ADD42018">
        <property type="protein sequence ID" value="ADD42018"/>
        <property type="gene ID" value="Snas_2331"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2331"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_1_3_11"/>
    <dbReference type="OMA" id="VYASFWQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="61"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="261" mass="26896" checksum="F49F1F9389ACA965" modified="2010-04-20" version="1">MRIPLPGARLGYGLAGVAAAVGLAELLPRLGVVDPRHLPPVSRIAAALGTELGQSGFWLAVADTLAAWAQGLLIAVVAGVVCGVVIASVPGLRAATASTIEFLRPIPSVALIPLAILLLGTGIESTLLLVVYASFWQVLIQVIAGINDIDSVAADTARSFRLSAARRVWHLALPSALPYILTGVRLAASVALVLAVTAELVIGAPGLGHEISVAKTSAAVPRMYALIAVTGILGVAVNLAARGAERRLLRWHPSIRQEVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3M3</accession>
    <name>D3Q3M3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4291"/>
    <dbReference type="EnsemblBacteria" id="ADD43940">
        <property type="protein sequence ID" value="ADD43940"/>
        <property type="gene ID" value="Snas_4291"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4291"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1255332_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="11"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="220" mass="23802" checksum="59C0213BFE89F761" modified="2010-04-20" version="1">MSQANEKLAVEFIEAFGRGDREALTGYLTEDVVFESPRVRLAGVAEVSAAIAGFGTAITELSIETVFADEHRALVAYTMMAGPLGPLRAVDRLEFRDGRIAADTVVFDTYPVRRAEAPGRGTEATVIQYRTLPEAADANEKLVADVFEQLAAEDPGGVRYVSLRLDDGVGFVHVVINEPGGTNLTELSSFAEFQREFSDRVPDGPTRSGAKLIGQYRMVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4A0</accession>
    <name>D3Q4A0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6369</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6369"/>
    <dbReference type="EnsemblBacteria" id="ADD45985">
        <property type="protein sequence ID" value="ADD45985"/>
        <property type="gene ID" value="Snas_6369"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6369"/>
    <dbReference type="eggNOG" id="COG3023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015278_1_0_11"/>
    <dbReference type="OMA" id="MHTDPGP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049527" evidence="2">
        <location>
            <begin position="38"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="3">
        <location>
            <begin position="278"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="646" mass="69619" checksum="437C3A1166ABA586" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4H1</accession>
    <name>D3Q4H1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0414"/>
    <dbReference type="EnsemblBacteria" id="ADD40131">
        <property type="protein sequence ID" value="ADD40131"/>
        <property type="gene ID" value="Snas_0414"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0414"/>
    <dbReference type="HOGENOM" id="CLU_2439326_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="90" mass="9451" checksum="8E6D66F638398E80" modified="2010-04-20" version="1">MSAEVASTPLWIPVLLGGTLLLSLAAVVAVILLSVRVNKLSAELRARHPVQPMRPAPPPHGYGQQPQSPQPGQQPPLPPGQNPQQPPPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4P0</accession>
    <name>D3Q4P0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF402 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2386"/>
    <dbReference type="EnsemblBacteria" id="ADD42070">
        <property type="protein sequence ID" value="ADD42070"/>
        <property type="gene ID" value="Snas_2386"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2386"/>
    <dbReference type="eggNOG" id="COG3557">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120820_0_0_11"/>
    <dbReference type="OMA" id="AWVVANI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007295">
        <property type="entry name" value="DUF402"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035930">
        <property type="entry name" value="FomD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04167">
        <property type="entry name" value="DUF402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159234">
        <property type="entry name" value="SSF159234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF402" evidence="1">
        <location>
            <begin position="59"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="188" mass="21335" checksum="93AF408C63AC1C71" modified="2010-04-20" version="1">MSSSWVWRRGRKLKRADHVHGWWWEAVLGDDEHGQWAAQLAQAPTFLRDGTVFRMADAVIRCYPRDEWWVATFYGSERGVTFVRPGGGVDERLNPNAIYVDMSTPPEWTEAGISFVDLTVDVVKRYDGTIAVLDEDEVDEEARKWATPAGQLAQARHSRARVEGFMTAGVGVFGVVAESWRDRFEGCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4P2</accession>
    <name>D3Q4P2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2388</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017643.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2388"/>
    <dbReference type="EnsemblBacteria" id="ADD42072">
        <property type="protein sequence ID" value="ADD42072"/>
        <property type="gene ID" value="Snas_2388"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2388"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_0_0_11"/>
    <dbReference type="OMA" id="TIFIHEC"/>
    <dbReference type="OrthoDB" id="1919329at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="148" mass="16678" checksum="082B6E4202138927" modified="2010-04-20" version="1">MLGRLYPSQECSAARALELVGERWTLLILRDALFKDFTRFSQFQQSLSIAPNILTKRLNDLVDNGILRTHTAADRSDHHEYLLTEMGQTLKPVITSLTVWGDRWVRPGPAVFVHETCGTEVSQRYDCPHCGDTVAPEAVRANPRLTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4V6</accession>
    <name>D3Q4V6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2453</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017707.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2453"/>
    <dbReference type="EnsemblBacteria" id="ADD42136">
        <property type="protein sequence ID" value="ADD42136"/>
        <property type="gene ID" value="Snas_2453"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2453"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051161_0_0_11"/>
    <dbReference type="OrthoDB" id="1885303at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="380" mass="41332" checksum="0A799C6D6D4D79D0" modified="2010-04-20" version="1">MTWTTIAANWNHGCAVESHARPAVDPGLAFTVLRTACEPYLRGMRHYALPSVSFDADGELISAPGDRLPSSGDSDLDGYRDRLSSRAANWRLRAVEPLFTDYRLWHRVREQLTPLWSIVGMPVLPVASELIVAAGDVGLCESEASHLNLVFVLDGRVTLLDDGTEQELSEGDVVRIPAAGTAALRSSTASLSLRLRIPVDRRLPTADAVRLISRVVAAEAAELDEPVPELSFPPPTDGEELKLPAETVAPQRPPHRADYRAEAERLSRVWWAGRASAAGLDPVPDPAEPPPLRLEQRVRARVPVLVLPGEEPDQQLWAVNGMAFSVAGPTPGLVLDRLRGNDSVEVAELCRDADGQDNGAGPLLDRLRELRAIEIVEETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4X3</accession>
    <name>D3Q4X3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017724.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2470"/>
    <dbReference type="EnsemblBacteria" id="ADD42153">
        <property type="protein sequence ID" value="ADD42153"/>
        <property type="gene ID" value="Snas_2470"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2470"/>
    <dbReference type="HOGENOM" id="CLU_1460438_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="192" mass="19892" checksum="B1FB6FD45776B5C3" modified="2010-04-20" version="1">MTSLETTTKRPGPVSAAVNIQYFLIALGVLSAIFAAVNGDKINAAAKAELERLDASKLQIDAMANIGGSGALGLVIAAVSTVVFLLLTIMVAKGKQWARVTTWVLSGLGLVFSLLGLLGTLALSADDKLAKATEAGMEAAGSWYGPWQTAYLVLSVLGGLAVIILLALPAAHPFFRKAQPEAVLPPEAYTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5G9</accession>
    <name>D3Q5G9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Apurinic endonuclease Apn1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_6413</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AP endonuclease 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021600.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6413"/>
    <dbReference type="EnsemblBacteria" id="ADD46029">
        <property type="protein sequence ID" value="ADD46029"/>
        <property type="gene ID" value="Snas_6413"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6413"/>
    <dbReference type="eggNOG" id="COG0648">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025885_0_2_11"/>
    <dbReference type="OMA" id="HPGSHLK"/>
    <dbReference type="OrthoDB" id="1088517at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00019">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001719">
        <property type="entry name" value="AP_endonuc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018246">
        <property type="entry name" value="AP_endonuc_F2_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445">
        <property type="entry name" value="PTHR21445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00518">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00730">
        <property type="entry name" value="AP_NUCLEASE_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51432">
        <property type="entry name" value="AP_NUCLEASE_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="8">
        <location>
            <begin position="13"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD46029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="258" mass="27786" checksum="1BB791CB20C3A96F" modified="2010-04-20" version="1">MRIGSHVDASSPLDEAAKRGAEVVQFFIGDPQGWKKPESRPDAEALRASDVDIFVHAPYVINVASPNNRIRIPSRKLLLQQARVAAEIGAKGLIVHGGHVTKDEDMAVGFANWRKAFEFGADQGGFGLPILIENTAGGDKACARRLENIERLWEAVGDFDPGFCLDTCHAHAGGLDLSDVVDRAKAITGHIDLIHANDSRDTFDSGRDRHANLGAGHIDPQRIVDIISAARCPAVVETPGDAEAQSADIALIREHLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5I8</accession>
    <name>D3Q5I8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6432</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021619.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6432"/>
    <dbReference type="EnsemblBacteria" id="ADD46048">
        <property type="protein sequence ID" value="ADD46048"/>
        <property type="gene ID" value="Snas_6432"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6432"/>
    <dbReference type="eggNOG" id="ENOG5030H8U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1133053_0_0_11"/>
    <dbReference type="OrthoDB" id="1697184at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD46048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="245" mass="25470" checksum="A85DDB7DB8DCFA56" modified="2010-04-20" version="1">MTTNPAPHGDEADAAVTAGLRALSQSYPDMPSQVAERLERTLAELPELTAPDTALAPAPKPKQPWWRRRYALASASLAVAAFVAGGILIAQFTPMNSDAATNAEGNSESSVQPFDKERDNPGENDQSEKDSGTDSEGSAYRMSYSGTDYSESDLARARGLSATGDKAALDPALEPLSTDKSVRDACLSELTGTYGGSVESVDFGQYEGEPAMVAVVADESSGGTVAAVGPDCRSGDPQVLGSAKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5K7</accession>
    <name>D3Q5K7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6452</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021638.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6452"/>
    <dbReference type="EnsemblBacteria" id="ADD46067">
        <property type="protein sequence ID" value="ADD46067"/>
        <property type="gene ID" value="Snas_6452"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6452"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_976029_0_0_11"/>
    <dbReference type="OMA" id="RDAHACG"/>
    <dbReference type="OrthoDB" id="2089619at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041467">
        <property type="entry name" value="Sco4008_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17926">
        <property type="entry name" value="TetR_C_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="196"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD46067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="264" mass="29411" checksum="FBEEA71DEE6F7087" modified="2010-04-20" version="1">MKRGEATRQALLRAARDEFAEYGLAGARVDRVAEQAGVNKERIYSLFGSKDKLFDAILIDTMQEFTELVDPLDTEIELGDYVSRLYEFHRHHPQLQRLLLWEALHRGDDAHDIDGWRNAHYRKKIVAAMARFGADEKQAGLLLMALASLVNWPNALPQVNRLLLGESAGDRDAIRRFLVSFVRAAVRGHESEAESVKALTTDVEQAAARLRRAQAETDRARAELAHALRAANTDGESANQLAKRVAGTLSRPVVLKLLAEEPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5T6</accession>
    <name>D3Q5T6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0520</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0520"/>
    <dbReference type="EnsemblBacteria" id="ADD40235">
        <property type="protein sequence ID" value="ADD40235"/>
        <property type="gene ID" value="Snas_0520"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0520"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_9_4_11"/>
    <dbReference type="OMA" id="AWRHPEV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="26"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="123"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="20914" checksum="D5A8AA7FE791D54D" modified="2010-04-20" version="1">MDEATPSTGLSASMSADEQLIHALHAEHADALWRYACRLTGGDEARAQDAVQETLLRAWRNSRVLASSPDHARRWLYRTLRSRVIDEWRYRKNRPEVITDTLPERHAADHVDSALQGLLVVEALRKLSPAHREVLMECFYGGRSVNEAAEKLAIPAGTVKSRLHYALRALKLALEEAGVVRREER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5W3</accession>
    <name>D3Q5W3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015833.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0548"/>
    <dbReference type="EnsemblBacteria" id="ADD40262">
        <property type="protein sequence ID" value="ADD40262"/>
        <property type="gene ID" value="Snas_0548"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0548"/>
    <dbReference type="eggNOG" id="COG1950">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120441_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007165">
        <property type="entry name" value="Phage_holin_4_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37309">
        <property type="entry name" value="PTHR37309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04020">
        <property type="entry name" value="Phage_holin_4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="136" mass="15042" checksum="413E66EAEB308626" modified="2010-04-20" version="1">MKILLKILVTAATLWITTLIFDDIVIDTDSPLTYVGTLLFVALVFGLVNAIVKPIAKFMLKASCLYYLSLGILGLVLNALLFLLVIFVADQFGLPFTIEGEGFHRFWIALLASIVITVVSWVLNLVIPDKNDKKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5W7</accession>
    <name>D3Q5W7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0552</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0552"/>
    <dbReference type="EnsemblBacteria" id="ADD40266">
        <property type="protein sequence ID" value="ADD40266"/>
        <property type="gene ID" value="Snas_0552"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0552"/>
    <dbReference type="eggNOG" id="COG0674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1014">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017038_1_0_11"/>
    <dbReference type="OMA" id="LNPFPKN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022367">
        <property type="entry name" value="2-oxoacid/accept_OxRdtase_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03710">
        <property type="entry name" value="OAFO_sf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR" evidence="2">
        <location>
            <begin position="18"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="POR_N" evidence="3">
        <location>
            <begin position="255"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="617" mass="65834" checksum="5E735D71B0E6CC90" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5X6</accession>
    <name>D3Q5X6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0561</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015846.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0561"/>
    <dbReference type="EnsemblBacteria" id="ADD40275">
        <property type="protein sequence ID" value="ADD40275"/>
        <property type="gene ID" value="Snas_0561"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0561"/>
    <dbReference type="eggNOG" id="COG0802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087829_1_1_11"/>
    <dbReference type="OMA" id="SVIVVEW"/>
    <dbReference type="OrthoDB" id="1827295at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00150">
        <property type="entry name" value="T6A_YjeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="178" mass="19100" checksum="308C2435E5E4F0C4" modified="2010-04-20" version="1">MLLETVEDTWAFGARLAALLRPGDLLILTGSLGAGKTALTQGIGEGLKVEGTVASPTFVIARIHKGSTPLVHVDAYRLGGLDELDDLDLDATVEDSVTVVEWGAGVAEQLSSDHLEIRIDRRPDDVRELTLHPTGGDWAERLRALALSPVSARLSLASVVRGYRQKWGGGRRPRGLNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6G1</accession>
    <name>D3Q6G1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Vitamin B12-dependent ribonucleotide reductase</fullName>
            <ecNumber evidence="4 10">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Snas_4560</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ribonucleoside diphosphate reductase class-2 family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4 10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019775.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4560"/>
    <dbReference type="EnsemblBacteria" id="ADD44204">
        <property type="protein sequence ID" value="ADD44204"/>
        <property type="gene ID" value="Snas_4560"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4560"/>
    <dbReference type="eggNOG" id="COG0209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000404_0_1_11"/>
    <dbReference type="OMA" id="WACADPG"/>
    <dbReference type="OrthoDB" id="357568at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02888">
        <property type="entry name" value="RNR_II_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013678">
        <property type="entry name" value="RNR_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013344">
        <property type="entry name" value="RNR_NrdJ/NrdZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08471">
        <property type="entry name" value="Ribonuc_red_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02504">
        <property type="entry name" value="NrdJ_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="8 10" id="KW-0170">Cobalt</keyword>
    <keyword evidence="7 10" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonuc_red_2_N" evidence="13">
        <location>
            <begin position="58"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="RIBORED_LARGE" evidence="12">
        <location>
            <begin position="162"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD44204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="946" mass="103297" checksum="865DD7086B5BA118" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6H8</accession>
    <name>D3Q6H8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019792.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4577"/>
    <dbReference type="EnsemblBacteria" id="ADD44221">
        <property type="protein sequence ID" value="ADD44221"/>
        <property type="gene ID" value="Snas_4577"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4577"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="TTDYRSH"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="20"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="353" mass="38354" checksum="9A282EFBD1352222" modified="2010-04-20" version="1">MSNTLDNYRLLGSSGLRVSPLSLGAMTFGDDWGWGSDKADSRRIFDTYLERGGNFIDTANAYTAGTSEEYVGEFAEGNRDRVVIATKYSMSIRAGDPNAGGNGRKALRQSVEQSLRRLRTDHIDLLYLHAWDFTTSADEVMRGLDDLVRSGKVLYIGLSDIPAWQAARMQTIAELRGWEPLAAMQIQYSLIERTVERDLIPMAAELGMGVVPWSPLGSGVLTGKYTRADLDTQLTDDPKGTRKQVAAANGALTPRALDIADVVVAVAKEMEVAPAQVALAWTLLNPAVASPIIGARTLEQLESNLGALEVEFTDEQRERLDAASAIELGFPHDFLSGGMVNGVLHGGAKIQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6M0</accession>
    <name>D3Q6M0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_4620</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4620"/>
    <dbReference type="EnsemblBacteria" id="ADD44263">
        <property type="protein sequence ID" value="ADD44263"/>
        <property type="gene ID" value="Snas_4620"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4620"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_13_3_11"/>
    <dbReference type="OMA" id="QVRDAQW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048906" evidence="8">
        <location>
            <begin position="29"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="9">
        <location>
            <begin position="52"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="333"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="354"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD44263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="421" mass="43288" checksum="48DE271E3EB7151B" modified="2010-04-20" version="1">MRHRFIAAIGSLAVLTAMIVVAPMSAFADEPRSQEWIVDALRLKDVHKLSQGEGVTVGVIDSGVDADHPDLDGNVKAGKDFGTSKDDGLNDHDGHGTSVSSLIVGHGHGDSNTDGIIGIAPKAKVVSVGLRWGKGEGEKVGGYIAGAIKWLVDQKVDIISISMSGYPEISDAVKYAMDNGVPLVGSAGNTDKYADDPILGQVKNNTTGWPAMDAGAIPVSGTTQDNEFWEGSVQLSEAAVQPQFGLSAPATELVAATKGGGYGTFSGTSGSAPIVAGTLAIIKSAYPNLDYSSLVDRLLDTVDDKGPKGFDNKYGWGIVNPYKALTEETVYKGPTGKETVSDPADRLPLDEQGKGQGQQDNGNGSGNSDGALTPSGASSLLLPLCITAAVLVLAAAVVIAVVVAKRRAKTRGGSPQPPGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q710</accession>
    <name>D3Q710_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0696"/>
    <dbReference type="EnsemblBacteria" id="ADD40409">
        <property type="protein sequence ID" value="ADD40409"/>
        <property type="gene ID" value="Snas_0696"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0696"/>
    <dbReference type="HOGENOM" id="CLU_2439327_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="90" mass="10113" checksum="FE62C75B9E56D16A" modified="2010-04-20" version="1">MSAPGARSPGEEMPRGWDDAADTQDQDDDFVDEDSIWTPTKKALPPVLGRYDKDTGERLMHYSDDVIQNANKDEEFDWTDSEGTSIDIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q748</accession>
    <name>D3Q748_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017890.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2642"/>
    <dbReference type="EnsemblBacteria" id="ADD42319">
        <property type="protein sequence ID" value="ADD42319"/>
        <property type="gene ID" value="Snas_2642"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2642"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_2_11"/>
    <dbReference type="OMA" id="VELPCAW"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025828">
        <property type="entry name" value="Put_sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13796">
        <property type="entry name" value="Sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="336"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="426" mass="45385" checksum="AD841AC81468DECA" modified="2010-04-20" version="1">MNSDNTSGPGMFGRRVRITVRACGHLVGGIATALPALVTLGLLPLLTVSMSVLLIGVFGLPYLVLWIRVLAGRERRRLSRYLGRDAPAAYRRIEGPASTRLRIALTDGATGRDLLWLLFQATAGLVVSLFGLALSVAVLFAASVPLWWYLVPEGRPVSMLYPVDSWPDAVGMLGLAVGLFGIAMLAAPPLARWHARAGRRLLTSPTRRRKHLAEQVAELTASRAAALDAHGIELRRIERDLHDGVQNRLVAVTMHLGMVERALSREPSRPATALPLVREVQETAVEALAELRQVVRAVYPPILADRGLGGALAALAARCPISCDLRIGDLPPIPAALEATGYFIVAESLTNAVKHSGASRVEVSVSGGKGDLMVTVTDNGDGGADATGGTGLLGLRRRVEAHWGRFTLDSPPGGPTVIEAVLPCEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7C6</accession>
    <name>D3Q7C6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nitrite reductase (NAD(P)H), small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2721</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017968.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2721"/>
    <dbReference type="EnsemblBacteria" id="ADD42397">
        <property type="protein sequence ID" value="ADD42397"/>
        <property type="gene ID" value="Snas_2721"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2721"/>
    <dbReference type="eggNOG" id="COG2146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055690_3_0_11"/>
    <dbReference type="OMA" id="IDNRDPF"/>
    <dbReference type="OrthoDB" id="1681886at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008942">
        <property type="term" value="F:nitrite reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03529">
        <property type="entry name" value="Rieske_NirD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017881">
        <property type="entry name" value="NirD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012748">
        <property type="entry name" value="Rieske-like_NirD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40562">
        <property type="entry name" value="PTHR40562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13806">
        <property type="entry name" value="Rieske_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02378">
        <property type="entry name" value="nirD_assim_sml"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="5">
        <location>
            <begin position="3"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="113" mass="12444" checksum="B41FD1CC218EA780" modified="2010-04-20" version="1">MSWEPICALEQLTPERGRAALLPDGTQVALFRTRDDDLFAVENLDPFSNAYVMSRGILGDRAGTPTVASPMYKQVFDLATGECKDAERVRLRTFEVSCRDGVVAVRVPEAVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7E4</accession>
    <name>D3Q7E4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2739</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017986.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2739"/>
    <dbReference type="EnsemblBacteria" id="ADD42415">
        <property type="protein sequence ID" value="ADD42415"/>
        <property type="gene ID" value="Snas_2739"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2739"/>
    <dbReference type="eggNOG" id="COG1141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_6_0_11"/>
    <dbReference type="OMA" id="AMAIHIE"/>
    <dbReference type="OrthoDB" id="1873445at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001080">
        <property type="entry name" value="3Fe4S_ferredoxin"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00352">
        <property type="entry name" value="3FE4SFRDOXIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 4" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="64" mass="6824" checksum="5C62C69913D46F8E" modified="2010-04-20" version="1">MHVKADTDKCVGAGQCVLVAAAVFDQRETDGIVELLQPEPPGETHDAVREAALLCPTHAIQVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7H3</accession>
    <name>D3Q7H3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4672"/>
    <dbReference type="EnsemblBacteria" id="ADD44315">
        <property type="protein sequence ID" value="ADD44315"/>
        <property type="gene ID" value="Snas_4672"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4672"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_663755_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="414" mass="46231" checksum="80ED26164797CC9B" modified="2010-04-20" version="1">MARHFAYPAIDPKPGHRVVGRPAIIWSAPHLPGPEGDNPLGLSHWDQKGFRRHRRRQWMYISVTVALAASMLVVAWRYGDGFAQNLLVELGGGLLLLVGAGVLLDKALTRFQVREVEALRNLDQNAVAENFAASHRQIDILGGWSSLLTERHAKSTIDSLRSAIGKGATVRVLLLNPYGDPARIRSEELGHNPNVPEEIVRQLRKLHEFSTELPRDQRPRIVVRLYSTMPAVQANRWDDKMVMAFLSPTRPTNETQQLETFVSTPLAEFVIDKFETIWNGATISFGEYMSTTGVLKGRNGSELTSALEYFRVGNVTYVSGEELSEWLDHHALTEVRLTWAPAQNLGISPGTYWLDRVTESGGATDESAKPRALQEAKRVRRHYEAKYGKSSLPIYRLIRDEPGPAAATDAPTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7N7</accession>
    <name>D3Q7N7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GyrI-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019950.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4737"/>
    <dbReference type="EnsemblBacteria" id="ADD44379">
        <property type="protein sequence ID" value="ADD44379"/>
        <property type="gene ID" value="Snas_4737"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4737"/>
    <dbReference type="eggNOG" id="COG4832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083625_0_0_11"/>
    <dbReference type="OMA" id="GKHHEIY"/>
    <dbReference type="OrthoDB" id="1748122at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008319">
        <property type="entry name" value="UCP031644"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031644">
        <property type="entry name" value="UCP031644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GyrI-like" evidence="1">
        <location>
            <begin position="18"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="204" mass="23386" checksum="4D635529D006DDF8" modified="2010-04-20" version="1">MLKQDLKKVHRDLYGPKTEPELVEVPTRAFLMIDGHGDPDVESSGYGAAVEALYTVAYTLRFALKKAEVIEYPVPPLEGLWWTDEFSDTPEWLRRDEWNWTMMIPQPPQVDAVGFADAVASARRKKGEREEFGRVRFEEFTEGLSAQILHIGPYSSEPETMERLNAFVKDKGLSWTGRHHEIYLSDPRKAVPERMKTILRHGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7S3</accession>
    <name>D3Q7S3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019986.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4773"/>
    <dbReference type="EnsemblBacteria" id="ADD44415">
        <property type="protein sequence ID" value="ADD44415"/>
        <property type="gene ID" value="Snas_4773"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4773"/>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089574_6_4_11"/>
    <dbReference type="OMA" id="REGIQDW"/>
    <dbReference type="OrthoDB" id="2056793at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="13"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="104" mass="11146" checksum="D7EBAE5071DA6BB2" modified="2010-04-20" version="1">MTALITRDELAKDIANLTVVDALGAEYHAKRHLPGAVPLAPGEVEARAAEVLPDRDAAIVTYCSNVACPNSGQVADKLTKLGYTNVRKYREGIEDWADAGLPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q872</accession>
    <name>D3Q872_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rieske (2Fe-2S) domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2770</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018017.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2770"/>
    <dbReference type="EnsemblBacteria" id="ADD42446">
        <property type="protein sequence ID" value="ADD42446"/>
        <property type="gene ID" value="Snas_2770"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2770"/>
    <dbReference type="eggNOG" id="COG4638">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026244_3_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015879">
        <property type="entry name" value="Ring_hydroxy_dOase_asu_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001663">
        <property type="entry name" value="Rng_hydr_dOase-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43756">
        <property type="entry name" value="PTHR43756"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00848">
        <property type="entry name" value="Ring_hydroxyl_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00090">
        <property type="entry name" value="RNGDIOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="6">
        <location>
            <begin position="34"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="398" mass="44820" checksum="76DD774C0180171A" modified="2010-04-20" version="1">MTAVNHQILRPETYYSREWFDREQAELFGDTWQFAGMADDYGPPGAFQSVQAGRHPLVVLRDGEGVLRAFHNLCRHRGAAVLPQSGVVKRAIVCPYHNWTYGLDGCLLATPQRKELDPAPDRSTLGLHPAGLAQWQGMLFVHPDPAAQPLDEWLADLPQRVAPVDPLELTEPGEPEVHHLKCNWKIFMENALDNYHLGYVHRDNLAEYDHKRQEQHQCGQWHWSFYEPPKKPGHMPPSEVRAGLRPIHIDPRWYGSSFGMIFPNTFVLTGPTFWVSVEVIPTGAETTTVRLRARVAAGQNGALARGLVTEAAARVFRPIRSLAGGMVSAIRTRSSVRAAIRKASQDQRRYTVVEEDVFCCEALQRGIRSPRFSIGPVAPRLERGVLTFQQNVRDYLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8I7</accession>
    <name>D3Q8I7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribulokinase</fullName>
            <ecNumber evidence="3">2.7.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2886</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP + L-ribulose = ADP + H(+) + L-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:22072"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16880"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58226"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribulokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.16" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018132.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2886"/>
    <dbReference type="EnsemblBacteria" id="ADD42561">
        <property type="protein sequence ID" value="ADD42561"/>
        <property type="gene ID" value="Snas_2886"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2886"/>
    <dbReference type="eggNOG" id="COG1069">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009281_9_1_11"/>
    <dbReference type="OMA" id="GHKAMWH"/>
    <dbReference type="OrthoDB" id="1619686at2"/>
    <dbReference type="UniPathway" id="UPA00145">
        <property type="reaction ID" value="UER00566"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008741">
        <property type="term" value="F:ribulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019569">
        <property type="term" value="P:L-arabinose catabolic process to xylulose 5-phosphate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005929">
        <property type="entry name" value="Ribulokinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01234">
        <property type="entry name" value="L-ribulokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0054">Arabinose catabolism</keyword>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_C" evidence="4">
        <location>
            <begin position="292"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="556" mass="59615" checksum="CD1F58C0C2C78C3B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8J0</accession>
    <name>D3Q8J0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020003.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44432">
        <property type="protein sequence ID" value="ADD44432"/>
        <property type="gene ID" value="Snas_4791"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4791"/>
    <dbReference type="HOGENOM" id="CLU_121293_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="18698" checksum="9D1EBF94B70E8876" modified="2010-04-20" version="1">MGRLADTLDALSVRALSPDHRIQGQLHHRTKVDISFTSEDSYYEYKSEQAVAAQLSAVLNALIVGRNEGFCAAVREVTDLRLDDRPHWDARRRRFREERDGAPLEGQSAGGWLTVASVGLRDANATVKPGAFDELDASGFLIEVHSAIADLWKDQAMAMSYLRRTHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8L3</accession>
    <name>D3Q8L3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4814"/>
    <dbReference type="EnsemblBacteria" id="ADD44455">
        <property type="protein sequence ID" value="ADD44455"/>
        <property type="gene ID" value="Snas_4814"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4814"/>
    <dbReference type="eggNOG" id="ENOG5032CNN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_209514_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="47" mass="5034" checksum="DD264BC80227DFB5" modified="2010-04-20" version="1">MELILWIIAVILVVAGIFQLFKGKLLWGIVLIIVGLLVGPGGVSIFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8P6</accession>
    <name>D3Q8P6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyltransferase (Isoleucine patch superfamily)-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4847</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020059.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4847"/>
    <dbReference type="EnsemblBacteria" id="ADD44488">
        <property type="protein sequence ID" value="ADD44488"/>
        <property type="gene ID" value="Snas_4847"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4847"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_7_0_11"/>
    <dbReference type="OMA" id="CTISAYQ"/>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="179" mass="19844" checksum="4FC194295C60E595" modified="2010-04-20" version="1">MWRLRFTPDYLRFAWLRLRRPWIRCRGMVYLGRRVTLTARRTYGRLILGRDVRLGADCAIRAHEGTVHIGDRCVFGARVTVNSYLDIHIGPETLIADDVYIIDFDHRFADTTTPIMDQGIVKSAVRVGSGCWLGTKVTVTRGVRIGDGAVIGAGSVVTRDIPPNAIAAGVPARVIGERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q960</accession>
    <name>D3Q960_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0234 protein Snas_0959</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0234 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016240.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40669">
        <property type="protein sequence ID" value="ADD40669"/>
        <property type="gene ID" value="Snas_0959"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0959"/>
    <dbReference type="eggNOG" id="COG1666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099839_0_0_11"/>
    <dbReference type="OMA" id="SDFDRQE"/>
    <dbReference type="OrthoDB" id="1612988at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd11740">
        <property type="entry name" value="YajQ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00632">
        <property type="entry name" value="UPF0234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007551">
        <property type="entry name" value="DUF520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035571">
        <property type="entry name" value="UPF0234-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035570">
        <property type="entry name" value="UPF0234_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036183">
        <property type="entry name" value="YajQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30476">
        <property type="entry name" value="PTHR30476"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04461">
        <property type="entry name" value="DUF520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89963">
        <property type="entry name" value="SSF89963"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="164" mass="17947" checksum="D249F809FF0E6C9A" modified="2010-04-20" version="1">MANPSFDIVSELDSAELDNAINQTSKELSTRFDFRGTGAGIERSGDEAVVLTAETEDRVKAALDVFKDKLIKRGISLKAMEAGEPRASGKTSKIDCALKQGIEQDVAKKINKAIRDEGPKGVQTQIQGDQIRVTAKKRDDLQSVIAMLKKADFDVALQFTNYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q961</accession>
    <name>D3Q961_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016241.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0960"/>
    <dbReference type="EnsemblBacteria" id="ADD40670">
        <property type="protein sequence ID" value="ADD40670"/>
        <property type="gene ID" value="Snas_0960"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0960"/>
    <dbReference type="eggNOG" id="COG3021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052333_1_0_11"/>
    <dbReference type="OMA" id="CNAIATE"/>
    <dbReference type="OrthoDB" id="1387978at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="106"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="35304" checksum="B40AB7AA284C41A7" modified="2010-04-20" version="1">MSSPRSRTPLRRVTYVLLWIMVLGWALFTGWRLFGAEVAWPVAVVISYTPYIAAAILIPIAVAVWLRTIALLTVLVVCACALVVVLMPRFFADGDGAGDGPQLRVMTANVLTGDADLDAIADLVVDNKIDVLTVLELDADAVDKLAKTEVADQLPHQVLKPADKAAGTGIYSRHELTENDELAVDGLFYNPAATIDVPKAGDVEFVAVHPSPPINPDRTRHWRHDLRALPPAPTDGTPRILAGDFNATLDHRILRDLIAMGYTDAADATGSGLTGTWPTDKNFPPKVTIDHVLTSTGITPTTYATHTIPNSDHRALTTTMTLPKPDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9H8</accession>
    <name>D3Q9H8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase molybdopterin binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2986</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2986"/>
    <dbReference type="EnsemblBacteria" id="ADD42660">
        <property type="protein sequence ID" value="ADD42660"/>
        <property type="gene ID" value="Snas_2986"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2986"/>
    <dbReference type="eggNOG" id="COG2041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040538_0_0_11"/>
    <dbReference type="OMA" id="FYPLHFY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidored_molyb" evidence="2">
        <location>
            <begin position="263"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="395" mass="43376" checksum="7C3AFED4E4619616" modified="2010-04-20" version="1">MADMVSSKRVARAATVVRRHRLSPFRDGAFSTFLHNPRTATVLGRLIAACFALCLLTGLYSHFLQEPLGWMTFPVRPVWLYRLSQGLHVATGTALIPLLLAKLWTVYPRLFTWPVVRSPLHALERLSIAVLVATSLLQLFLGFANTVKWYPWSFSFRTVHFWLSLVILGSLLIHIAVKLPLLRGNWRKPKDPEPTPASGWSRRGFFATVAAATVAVTVTTVGQSFTPLGGLALLAPRKPGVGPQGLPVNRTAAQANVTETATDAGYRLTVRGPRTYSLSLDELNALPQHEVELPIACVEGWSQNARWGGVRLRDLLKRAGAPPDADVEVASLETDGHYRTSRMGPEFAQDAATLLALRLDGETLHIDHGYPARLIAPARPGVLQTKWVATIEVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9M9</accession>
    <name>D3Q9M9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsD</name>
        <name evidence="10" type="ordered locus">Snas_4934</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="6">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020146.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4934"/>
    <dbReference type="EnsemblBacteria" id="ADD44575">
        <property type="protein sequence ID" value="ADD44575"/>
        <property type="gene ID" value="Snas_4934"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4934"/>
    <dbReference type="eggNOG" id="COG0522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092403_0_3_11"/>
    <dbReference type="OMA" id="PVICDEQ"/>
    <dbReference type="OrthoDB" id="1211060at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="PTHR11831:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S4" evidence="9">
        <location>
            <begin position="2"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="S4" evidence="8">
        <location>
            <begin position="91"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD44575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="23301" checksum="4355BBD1829E765D" modified="2010-04-20" version="1">MNRPRPKAKRSRALGIALTPKCVKYFERRPFPPGQHGRRRRSESDYSRRLLEKQRLREQYNIREAQMKRAFAEAVRRDGKTGDNLVSLLERRLDAFVLRAGFARTIYQSRQQVVHRHFLVNGRRVDKPSYRLKPGDVVQVAPGSRDKTPFQLAAAGAWAGSGPLPGYLEAKLPELKARLIAEPPRAQVPVVCDEQLVVEFYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA60</accession>
    <name>D3QA60_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016343.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1062"/>
    <dbReference type="EnsemblBacteria" id="ADD40772">
        <property type="protein sequence ID" value="ADD40772"/>
        <property type="gene ID" value="Snas_1062"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1062"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104845_0_1_11"/>
    <dbReference type="OMA" id="VANYVGF"/>
    <dbReference type="OrthoDB" id="1956412at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd02199">
        <property type="entry name" value="YjgF_YER057c_UK114_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013813">
        <property type="entry name" value="Endoribo_LPSP/chorism_mut-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14588">
        <property type="entry name" value="YjgF_endoribonc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjgF_endoribonc" evidence="1">
        <location>
            <begin position="6"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="151" mass="15627" checksum="322D918C2CAB6BE2" modified="2010-04-20" version="1">MSDHLARLTELGLTLPPVVPPVAAYQPAIRSGAHVYVSGQVPMVDGKLPEVGPVDTLELERAQELARICALNGLAAIDALVGLNAVVRIVKVTGYVAASDVYTDHPKVINGASELLGEVFGEAGRHARAAVGVSSLPMGAPVEVDMIAEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAF3</accession>
    <name>D3QAF3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acetylornithine aminotransferase</fullName>
            <shortName evidence="2">ACOAT</shortName>
            <ecNumber evidence="2">2.6.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">argD</name>
        <name evidence="4" type="ordered locus">Snas_3065</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L-glutamate 5-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:18049"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.6.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="2">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.11" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018307.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3065"/>
    <dbReference type="EnsemblBacteria" id="ADD42736">
        <property type="protein sequence ID" value="ADD42736"/>
        <property type="gene ID" value="Snas_3065"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3065"/>
    <dbReference type="eggNOG" id="COG4992">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_10_1_11"/>
    <dbReference type="OMA" id="PFMVPTY"/>
    <dbReference type="OrthoDB" id="572533at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00109"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003992">
        <property type="term" value="F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01107">
        <property type="entry name" value="ArgD_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004636">
        <property type="entry name" value="AcOrn/SuccOrn_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00707">
        <property type="entry name" value="argD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="107"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="222"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="401" mass="41387" checksum="2878A66A8BBE2B72" modified="2010-04-20" version="1">MTATQDLRERFTDALMPNYGTPGVALSHGDGTTVYDVDGNEYLDFIGGIAVSALGHAHPALVTAVSEQVARIAHTSNLFLHEPEVALAEKLLSLVGEPGKVFFSNSGTEANECALKLAIANGKAKGRTYFVASTDGFHGRSMGALALTGKAAIREPFAPFGIDVRFVPYGDAAALNDAVDESCAAVILEPTQGETGVVPPPEGYFAAVRDICDTTGALFIADEIQSGIGRTGTWFAYQQTGIVPDVVTLAKGLGGGLPIGACIGIGAYGDVFAKGDHGSTFGGNPVATAAALAVLDTIESDKLTEAAADKGKRLAEGIRALNHPLVAEVRGKGLWLGVELTAEVAADVDSTLRSSGVLANPVRPNVIRLAPPLVVTDAQIDAFLSVLPRALDAAYPPGGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAG3</accession>
    <name>D3QAG3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3075"/>
    <dbReference type="EnsemblBacteria" id="ADD42746">
        <property type="protein sequence ID" value="ADD42746"/>
        <property type="gene ID" value="Snas_3075"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3075"/>
    <dbReference type="eggNOG" id="ENOG5030I0S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_518656_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027860">
        <property type="entry name" value="DUF4429"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14472">
        <property type="entry name" value="DUF4429"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4429" evidence="2">
        <location>
            <begin position="10"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4429" evidence="2">
        <location>
            <begin position="134"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="525" mass="57241" checksum="C4BDDA2CEEBA8D8A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAU0</accession>
    <name>D3QAU0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ion transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5101</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5101"/>
    <dbReference type="EnsemblBacteria" id="ADD44736">
        <property type="protein sequence ID" value="ADD44736"/>
        <property type="gene ID" value="Snas_5101"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5101"/>
    <dbReference type="eggNOG" id="ENOG502Z7ZD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055047_0_0_11"/>
    <dbReference type="OMA" id="IRMIPAI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043227">
        <property type="term" value="C:membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005261">
        <property type="term" value="F:cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003915">
        <property type="entry name" value="PKD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043203">
        <property type="entry name" value="VGCC_Ca_Na"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037">
        <property type="entry name" value="PTHR10037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01433">
        <property type="entry name" value="POLYCYSTIN2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans" evidence="7">
        <location>
            <begin position="43"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="304" mass="33807" checksum="ACC3F5213B98066C" modified="2010-04-20" version="1">MPSRRRIVPVRMDTTSPDPSLPPAPDIPPQPLARMCHRVAYAPWFQWTSTAVIVLNAIVIGVGTYQEATAQFGWLLNLLDEAFLIYFVVELVIRIGSFGTTPWRFFRKGWNIFDFIVIAAALLPGIRENVTLLRLVRLARTVRLMKAFPSLRILLTAVARSMPGALGLLGVCVVVLYLYGMVGWILFAEAEPTEYGSVGQAALTLFGLLTLDNVGEVVRDGMEVTAWAVPYYVSYIFLAGFILVNLLVGVVITSMEEARQIEGAQTNFRSREPETSADTAEILARLEALQRSLNELQSRDDSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAV0</accession>
    <name>D3QAV0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase M16 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5111</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5111"/>
    <dbReference type="EnsemblBacteria" id="ADD44746">
        <property type="protein sequence ID" value="ADD44746"/>
        <property type="gene ID" value="Snas_5111"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5111"/>
    <dbReference type="eggNOG" id="COG0612">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009902_3_3_11"/>
    <dbReference type="OMA" id="IDVVCDM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="3">
        <location>
            <begin position="28"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="4">
        <location>
            <begin position="182"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="438" mass="47197" checksum="96D4BBF6000B6729" modified="2010-04-20" version="1">MTRAFTRTLADDPLGGTVRRTVLPGGLRVLTESIPAMRSASVGVWVGIGSRDESQQLSGASHFLEHLLFKGTNRRSALDISAQIEAVGGETNAYTAKEFTCYYARVLDEDVPLAIDVLADVITDSKLDADDVETERGVILEEIAMQRDEPGDEVHDIFAALMFGDHPLAHDISGTPASIEAMDRDQIHRFYKRRYTAPHMVVAAAGNVDHEQVVTLVQKGFAPLLSDVDAEPAPLRDETATVPPAPTRLRVATRDSEQAHLVLGCHGLARRDERRFAFEVLGGILGGGMSSRLFHRIREDEGLAYSVFSSTSEYAETGLFSVYAGCTPDNAHRVLELTNEVLAEIAADGVTASELKRGKGMVKGGLVLGMEDTGSRMARLGRGELLFGDKLTVDEILAKVDAVTLADVAELAAVVLSRPRSLAVAGPFTESDFSGHVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB90</accession>
    <name>D3QB90_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplE</name>
        <name evidence="9" type="ordered locus">Snas_1197</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016478.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1197"/>
    <dbReference type="EnsemblBacteria" id="ADD40907">
        <property type="protein sequence ID" value="ADD40907"/>
        <property type="gene ID" value="Snas_1197"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1197"/>
    <dbReference type="eggNOG" id="COG0094">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061015_2_1_11"/>
    <dbReference type="OMA" id="ERMYAFL"/>
    <dbReference type="OrthoDB" id="1456375at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_L5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_L5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="7">
        <location>
            <begin position="33"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="8">
        <location>
            <begin position="93"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="192" mass="21424" checksum="A3427CC87F99393E" modified="2010-04-20" version="1">MATATDTKVTPRLKERYKAEIATALNEQFGYGNVMQIPTVQKVVVNMGVGDAARDSKLINGAMTDLATITGQKPQMRRATKSIAQFKLREGMPIGAKATLRGDRMWEFLDRLLSIALPRIRDFRGLSDKQFDGNGNYTFGLTEQSVFHEIDQDKIDRVRGMDITVVTTAKTNDEGRALLKLLGFPFKTAENH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB92</accession>
    <name>D3QB92_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsH</name>
        <name evidence="7" type="ordered locus">Snas_1199</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016480.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1199"/>
    <dbReference type="EnsemblBacteria" id="ADD40909">
        <property type="protein sequence ID" value="ADD40909"/>
        <property type="gene ID" value="Snas_1199"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1199"/>
    <dbReference type="eggNOG" id="COG0096">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098428_0_1_11"/>
    <dbReference type="OMA" id="FDQGYIL"/>
    <dbReference type="OrthoDB" id="1692188at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_S8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="135" mass="14965" checksum="0F9E5CBEF3B5F8E1" modified="2010-04-20" version="1">MTMTDPIADMLTRLRNANRAFHDVVAMPHSKLKANVAEVLKQEGYLADWHVEEPGEDEVSKKLVLDLKFGENRQRSLAGIRRVSKPGLRVYAKSTELPRVLGGLGVAIISTSQGLLTDRQARKRGVGGEVLAYVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBA3</accession>
    <name>D3QBA3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016491.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1210"/>
    <dbReference type="EnsemblBacteria" id="ADD40920">
        <property type="protein sequence ID" value="ADD40920"/>
        <property type="gene ID" value="Snas_1210"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1210"/>
    <dbReference type="eggNOG" id="COG4758">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102484_4_1_11"/>
    <dbReference type="OMA" id="WRYWLGG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012551">
        <property type="entry name" value="DUF1707"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08044">
        <property type="entry name" value="DUF1707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="165" mass="18572" checksum="D9D1BCF9B5CE682D" modified="2010-04-20" version="1">MNDKDKLRIGDSDRELVSRLLKQAVDEGRLTLPEYDLRLQQVYEAKTVGDLDPITGDLMGSNQGVLAVTESGNLSTVHDAPPRRTRPRRDKTPAWVKWMWFGWLVPVTVCTTIWGIGLVTGGTGYMWPLWVAGTIGAPMACVTFMERFMIRPALIERDQQRLVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBC1</accession>
    <name>D3QBC1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1228"/>
    <dbReference type="EnsemblBacteria" id="ADD40938">
        <property type="protein sequence ID" value="ADD40938"/>
        <property type="gene ID" value="Snas_1228"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1228"/>
    <dbReference type="eggNOG" id="ENOG50347RZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1073284_0_0_11"/>
    <dbReference type="OMA" id="HEPHRSH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="259" mass="30014" checksum="4E6D624060A78004" modified="2010-04-20" version="1">MRLFPKYLKKLSSRMRIEFDSSDVRKTATERTELPVPLYVAAIGGVFDFTVDCTLVWKSRDYTARRLRIEIPKCEERAIEDIEYRVLEMGHRFHAEQSEALEAALTREFRSSAGTFTSRRGRIQCLPHVRVNIDPDVRQTLRPNHLRRLQLDGEHTNNMRRADLVDTLSRRWSDLLGNIKDEPLIAHAAALTDEEFADVIKEMNARRQLHSYELLDLLREANERAGDLKMGAFEWAQAFDRALKQQPGAESVFQQSDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBG2</accession>
    <name>D3QBG2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">5'-3' exonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018415.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3173"/>
    <dbReference type="EnsemblBacteria" id="ADD42844">
        <property type="protein sequence ID" value="ADD42844"/>
        <property type="gene ID" value="Snas_3173"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3173"/>
    <dbReference type="eggNOG" id="COG0258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004675_1_3_11"/>
    <dbReference type="OMA" id="WRVDLIP"/>
    <dbReference type="OrthoDB" id="1220182at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033567">
        <property type="term" value="P:DNA replication, Okazaki fragment processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038969">
        <property type="entry name" value="FEN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42646">
        <property type="entry name" value="PTHR42646"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="53EXOc" evidence="2">
        <location>
            <begin position="2"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="303" mass="32136" checksum="39475024BEC0FFBE" modified="2010-04-20" version="1">MLVLVDAPGLWYRSFYGLPSSLRGPDGTQINAVRGFIDGLATLIRNHNATGLACAVDNDWRPAWRVDLLPSYKTHRLADNGGEEEPDALPHQVAIITQLLTAWGIPVIGVDGYEADDVLATLATTTKGPVGVATGDRDLFQLIDDDNDIRVIYFGRGIAKAETLDDAALVARHGVHPDQYVDFAVLRGDPSDGLPGVKGIGDKTAATLITTHGNLTDARAAAADPATTMAPRVRKALTESGEYLDAAVKVVRTANDAPVPDIDPSLRPEPADPQAVETLSDTYGLANSLNRLREALTAATGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBZ6</accession>
    <name>D3QBZ6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glycosyl transferase family 39</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_5251</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5251"/>
    <dbReference type="EnsemblBacteria" id="ADD44885">
        <property type="protein sequence ID" value="ADD44885"/>
        <property type="gene ID" value="Snas_5251"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5251"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007261_1_0_11"/>
    <dbReference type="OMA" id="WAMLVPQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="185"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="496"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="10">
        <location>
            <begin position="86"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="535"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD44885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="747" mass="77353" checksum="3F53460B82E54E14" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC17</accession>
    <name>D3QC17_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_5272</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020477.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5272"/>
    <dbReference type="EnsemblBacteria" id="ADD44906">
        <property type="protein sequence ID" value="ADD44906"/>
        <property type="gene ID" value="Snas_5272"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5272"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002554_0_1_11"/>
    <dbReference type="OrthoDB" id="811938at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013587">
        <property type="entry name" value="Nitrate/nitrite_sensing"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08376">
        <property type="entry name" value="NIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="476"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="675"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="819"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="690"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="880"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="925"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1014"/>
            <end position="1029"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD44906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1047" mass="112316" checksum="93B5CA108E071781" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU32</accession>
    <name>D3PU32_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016549.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1269"/>
    <dbReference type="EnsemblBacteria" id="ADD40978">
        <property type="protein sequence ID" value="ADD40978"/>
        <property type="gene ID" value="Snas_1269"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1269"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056342_1_1_11"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="49"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="331" mass="36286" checksum="01E1E2C32C49332D" modified="2010-04-20" version="1">MSKHVLPHEIQEHPTGYSGPNLTPVGLELLPRELGEGVVALMANVPPKDNNGVVFGERAALVVDAGITPTVGRRIRGHARELSPVAPKFLVNTTYHGDHTFGNLAFDDLTIVTSRANREFMDDLDREKRDRTDNMYGDEHLFEAFDAWRGPDVVFDSHTEIDLGGRTVELHHFGAGNGPGDTIVYVPSARTAWTGNYLCGAGSPHMLLQAGPTPYLESLRGMREALPELETIVPGHGPIGDGPRAVAALIEYLERLRDEVTAAFDAGYDVEETYRRCTDPWADGLDAEIAAALAEYEAPTQAVHSGFQRLARDLHRLNILTTYRVCEQLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU88</accession>
    <name>D3PU88_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1325"/>
    <dbReference type="EnsemblBacteria" id="ADD41034">
        <property type="protein sequence ID" value="ADD41034"/>
        <property type="gene ID" value="Snas_1325"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1325"/>
    <dbReference type="HOGENOM" id="CLU_107584_0_0_11"/>
    <dbReference type="OMA" id="DRICIAW"/>
    <dbReference type="OrthoDB" id="2007224at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025350">
        <property type="entry name" value="DUF4254"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14063">
        <property type="entry name" value="DUF4254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="164" mass="18240" checksum="72A197125D3F1E61" modified="2010-04-20" version="1">MLLTHLDSETEPAGGEPGRVVSVARRLRAHHDEQWQAEDLSRDAADDDAVVAKVKRRIDGMNVERSRMFDELDAWLSGELVQNPDAAPHTETIGSVVDRICIAWVRADRLSRKPNAEAMAVAARRQLTELAAAYDQLVSEVLTGRRRVPDWRALKSYGAGDDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUB1</accession>
    <name>D3PUB1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SNARE associated Golgi protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1349</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1349"/>
    <dbReference type="EnsemblBacteria" id="ADD41057">
        <property type="protein sequence ID" value="ADD41057"/>
        <property type="gene ID" value="Snas_1349"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1349"/>
    <dbReference type="eggNOG" id="COG0586">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044208_1_1_11"/>
    <dbReference type="OMA" id="FICYFIP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="241" mass="25840" checksum="F96ED3A27A11C2CB" modified="2010-04-20" version="1">MTTTEGVLGQITDWATSLMETMGGPGAGLAIALENLFPPIPSEVILPLAGFTAGQGKMNLFSAIIWTTAGSLVGAVALYYIGMVMGRDRIVRLAVKLPLIKLSDIEKTEAWFGKHGGKAVFFGRFIPIFRSFISIPAGLEKMAMPKFLLYTAGGSLIWNSIFILLGYKLGEHWEVVEEYVGAYSKGVIAVVLIAVVVFVVLRIRSMRRDRGEEEGPGDGGGDDATGGPQPQGGGVYRSRNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUC0</accession>
    <name>D3PUC0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1358</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016637.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1358"/>
    <dbReference type="EnsemblBacteria" id="ADD41066">
        <property type="protein sequence ID" value="ADD41066"/>
        <property type="gene ID" value="Snas_1358"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1358"/>
    <dbReference type="eggNOG" id="ENOG50336PU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1224319_0_0_11"/>
    <dbReference type="OMA" id="KGDHRSF"/>
    <dbReference type="OrthoDB" id="1700639at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025368">
        <property type="entry name" value="DUF4272"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14094">
        <property type="entry name" value="DUF4272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="224" mass="25462" checksum="13A0E5314F0622B9" modified="2010-04-20" version="1">MTSLLFDPRHIRTRTCDDLAQLGVKVHPDYLPLIFAPGEDISLRSLRDIEARSAILNVVQARVFDMPPQLAMRWLLDAHVLEELTPDEWQFIATGKGTPQRYSEQLECLFALAWTLGLVPHLDPSEYCSDALPSLMPDLRTSESFTTWKARTLPACRDAVEIAEMLDLYSCLDWLYSDARSRRAAPPGPLDESLLWHRRWALEWVVVLTGRGRSGGSTWDKVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUD0</accession>
    <name>D3PUD0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3273"/>
    <dbReference type="EnsemblBacteria" id="ADD42943">
        <property type="protein sequence ID" value="ADD42943"/>
        <property type="gene ID" value="Snas_3273"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3273"/>
    <dbReference type="HOGENOM" id="CLU_2883736_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="63" mass="6817" checksum="91079EDFE4060732" modified="2010-04-20" version="1">MSTTDEPLVAALLGAHDLPADPRERRGLTAVYRAQRPAVAAMYTVAPNTDSPHDTPEVDDDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUP0</accession>
    <name>D3PUP0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3389</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018624.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3389"/>
    <dbReference type="EnsemblBacteria" id="ADD43053">
        <property type="protein sequence ID" value="ADD43053"/>
        <property type="gene ID" value="Snas_3389"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3389"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051161_0_0_11"/>
    <dbReference type="OMA" id="HALRGIE"/>
    <dbReference type="OrthoDB" id="1885303at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="394" mass="43438" checksum="B54A148BEC642389" modified="2010-04-20" version="1">MDDWIASVSKGWRTQPVHVPHAWHDPPLDPDRLFALTVRASLPFRAGFRFQAVTDVRFSTATGIISAPGDLLPDDSDANWEAYRRRLPDDITGPGFRITVTQPLWLDFPLWSRVRDLVRPLWESVGYPVLPVAAEINHGGGHRTGHPPLRDSGNAVLTFVLRGRLTTQVFESDAPDEPAAEKWDTSTGGVVYLPAGTRFADNHDADCVTLRLRIPADRRLASASVFDLVNNMIDSRRISDKVPYVDQDALRYDHGGLATVPGLADTGHAFRELVATSNLPRIMRILWTRRVSACGLEPAPAPRHEISLYREQLVRLREQPVRMPQADDSAMWAVNGHVFAVEGSAADHILDRLRGGEAVRVGALWGQAGPTGGITALLSKLHALRGIDLVKENG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUQ1</accession>
    <name>D3PUQ1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5291</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020496.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5291"/>
    <dbReference type="EnsemblBacteria" id="ADD44925">
        <property type="protein sequence ID" value="ADD44925"/>
        <property type="gene ID" value="Snas_5291"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5291"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_686731_0_0_11"/>
    <dbReference type="OMA" id="FGFTVMY"/>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="397" mass="41404" checksum="0665C7F6E97047D4" modified="2010-04-20" version="1">MVTDREYRRFLILFMVNGGASSAGMPLVSLFLTQELDASLAEVGVVTVAGLLVIVTGPVVGGLSDRMRSRSPLMVGLAVWMAAGWAVYPFVDVFWLAIAVQVVMLSWIGPLNAQIFASLSETLEERAAPNASTITSTLRGGYSLGFMIGPVVSTALVTLVDLRTAFALAVALYLVTATLGWRSPVAAKRARGDGEPKAKARNGSILPLLVFASGACLVMVGDMLRAVYLPIYVVEELGHSAAMFGALISVAAGLEILAFPLVGRLADRFGVRRVMMAGLGAGIAAHTVLATSSSLWQVWLFTVLTVVVFTVTMGLGVTYAQSLAPGQRGLAASMFFSAQTGAMPVSGIVTAAAVGSLGLPGIFWVPAGLCAVCLVALVLASRRTSRRPAAEAAAEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUY4</accession>
    <name>D3PUY4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arsenical-resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5376</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020579.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5376"/>
    <dbReference type="EnsemblBacteria" id="ADD45008">
        <property type="protein sequence ID" value="ADD45008"/>
        <property type="gene ID" value="Snas_5376"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5376"/>
    <dbReference type="eggNOG" id="COG0798">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022869_0_0_11"/>
    <dbReference type="OMA" id="GGNKEYG"/>
    <dbReference type="OrthoDB" id="1493959at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015103">
        <property type="term" value="F:inorganic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="PTHR43057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="328"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR005508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="367" mass="39327" checksum="5231569CDF4815FD" modified="2010-04-20" version="1">MPVTSAPDLAATAAPAARKLSLVDKLLPAWILVAMAAGLLLGRSIPGLNSAMQAIEIGGVSLPIALGLLLMMYPVLAKVRYDRLDTVTGDRRLLVSSLVVNWLVGPAVMFALAWIFLPDLPEFRTGLIIVGLARCIAMVIIWNDLACGDREAAAVLVALNSVFQVLAFGLLGWFYLDILPGWLGLAQSDLDVSAWSIFVNVLIFLGIPLAAGYLTRRLGERAKGRDWYETRFLPKIGPIALYGLLFTIVILFALQGKAITAQPGDVARIAIPLLVYFALMWAGPFALGKLIGLGYDRATTLAFTAAGNNFELAIAVAIATFGVTSGQALAGVVGPLIEVPVLVGLVYVSLWARRYFPGNTRPQEVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV86</accession>
    <name>D3PV86_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016710.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1433"/>
    <dbReference type="EnsemblBacteria" id="ADD41139">
        <property type="protein sequence ID" value="ADD41139"/>
        <property type="gene ID" value="Snas_1433"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1433"/>
    <dbReference type="eggNOG" id="COG4279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122386_0_0_11"/>
    <dbReference type="OMA" id="PCKHGSA"/>
    <dbReference type="OrthoDB" id="1906220at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="211" mass="23289" checksum="758CA4CC414A4572" modified="2010-04-20" version="1">MSRFGVTWWGKRWLRTLEQLGLTYPDSRMATGRTLASKDAVDLMNVETGELSAWVDAPRKSFGVVVSVEPFTEEQWRTFDTVVASRLGNLADLLDDRLPTGIDRQLEPHGLTLFPGDDEIDTSCPCRDKTKVCVHVIALQHAFAVNFDDDPYLLGVLRGRDRETMLTALRSAGPGHEDLPPVSVDGAVPIASLSVADFYTGRGSFDALLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV96</accession>
    <name>D3PV96_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc D-Ala-D-Ala carboxypeptidase</fullName>
            <ecNumber evidence="4">3.4.17.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1443</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.17.14" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016720.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1443"/>
    <dbReference type="MEROPS" id="M15.001"/>
    <dbReference type="EnsemblBacteria" id="ADD41149">
        <property type="protein sequence ID" value="ADD41149"/>
        <property type="gene ID" value="Snas_1443"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1443"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1119635_0_0_11"/>
    <dbReference type="OMA" id="RSKACND"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009046">
        <property type="term" value="F:zinc D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013230">
        <property type="entry name" value="Peptidase_M15A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08291">
        <property type="entry name" value="Peptidase_M15_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049270" evidence="1">
        <location>
            <begin position="33"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="46"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M15_3" evidence="3">
        <location>
            <begin position="114"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="242" mass="25643" checksum="0035A883194F4794" modified="2010-04-20" version="1">MSDATRRALLSAAVMVPTSAAVIAMTSGTAHAAYSWDRKLKKGMKGNDVKQLQIRVAGYPGYGNILSLDGEFGARTESAVKRFQKAYGLAADGVAGSRTFRKIYSLQDGDNTPKHFSYAELNGCNSSWAGGTVSSTTAKYRALITMWKLEAMRHALGDKSISVSSGFRSKACNDAVGGASNSQHMTGSAADLVGSHSLCTLAKQARYHGFGTILGPGYDGHGDHVHLDGLNRIYWSAPNCGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVC2</accession>
    <name>D3PVC2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016746.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1471"/>
    <dbReference type="EnsemblBacteria" id="ADD41175">
        <property type="protein sequence ID" value="ADD41175"/>
        <property type="gene ID" value="Snas_1471"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1471"/>
    <dbReference type="HOGENOM" id="CLU_131550_3_3_11"/>
    <dbReference type="OrthoDB" id="1996962at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="1">
        <location>
            <begin position="16"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="76" mass="8180" checksum="2EF80DC6E5A368D4" modified="2010-04-20" version="1">MTSHNIARRLLTLDQAAWRKSIRSSSSGNGNCVEAASISTVVAIRDSKLAATVGFPVLTVDREDWTGFLTTVRTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVX2</accession>
    <name>D3PVX2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020664.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5461"/>
    <dbReference type="EnsemblBacteria" id="ADD45093">
        <property type="protein sequence ID" value="ADD45093"/>
        <property type="gene ID" value="Snas_5461"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5461"/>
    <dbReference type="eggNOG" id="COG3214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047003_2_0_11"/>
    <dbReference type="OMA" id="MQTWAGL"/>
    <dbReference type="OrthoDB" id="1819400at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009351">
        <property type="entry name" value="YcaQ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06224">
        <property type="entry name" value="HTH_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="367" mass="41014" checksum="0D4CE89537A417C0" modified="2010-04-20" version="1">MKTFDDRALNRARLHRQWLTERRDATPLETMEHLVGMQGQLGDPPYFQLWSRLNDFTTDDLSTLLEDRRAVRVVLMRGTIHLVSARDALTLRTLVQPYLSKTVFNGSEYGKRIQGVDPEALVEAGRRLLADKPLHVDELGAGLAEQFDGYAGGDLAYGLRGLMPLIQTPPRGVWGQGGGLTYASTGQWLGADPDTDWDAALDAAIPRYLAAYGPATIQDFQTWSSLTRTAPAFARLRDRLIVHRDAAGRELYDLPDIELPDLDGPLKPLLLGGFDNILLSHREREFVISKPAQKKVFRQNAMMKGTILIDGLVVGTWFTTLKKKTALLTFEPFESLSAKNRRYLEGEGERLLDFAAGTAETRTVEFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW77</accession>
    <name>D3PW77_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016805.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1530"/>
    <dbReference type="EnsemblBacteria" id="ADD41234">
        <property type="protein sequence ID" value="ADD41234"/>
        <property type="gene ID" value="Snas_1530"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1530"/>
    <dbReference type="eggNOG" id="COG0421">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101666_0_0_11"/>
    <dbReference type="OMA" id="KRAQWAL"/>
    <dbReference type="OrthoDB" id="1613081at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="238" mass="26121" checksum="222639D7C50ABC93" modified="2010-04-20" version="1">MRARFEELDWRETPMGELSLRRRVEPSLKVDVYEVKLGDEFLMSSLFTVAEIELARLGLAAATGTGLDVVVGGLGLGYTARAALADERVDRLLVVEALDAVIDWHQRELLPHADELTGDGRTGFVNGDFFALAADPRGFDPATPGRRFDAVLLDVDHSPRHVLHPSHAAFYTPDGLRALAAHLHPGGVFALWSNDPPDEQFTAVLGEVFTDVAAHVVSFPNHLQDRDSSNTVYTARTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW96</accession>
    <name>D3PW96_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TRAP C4-dicarboxylate transport system permease DctM subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1550</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016824.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1550"/>
    <dbReference type="EnsemblBacteria" id="ADD41253">
        <property type="protein sequence ID" value="ADD41253"/>
        <property type="gene ID" value="Snas_1550"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1550"/>
    <dbReference type="eggNOG" id="COG1593">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049437_0_0_11"/>
    <dbReference type="OMA" id="PIGLCLC"/>
    <dbReference type="OrthoDB" id="1128351at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004681">
        <property type="entry name" value="TRAP_DctM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33362">
        <property type="entry name" value="PTHR33362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="4">
        <location>
            <begin position="6"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="444" mass="45379" checksum="3D799801D4C44C14" modified="2010-04-20" version="1">MTAIYALAAFIAVIIVWNSVFKRNIAEAMVVGFMACCAFAGTGFLPLLVDSLWAGMQNEVTFAALAFVIVADILTRAGIVQRIVDIFGSLLGRRRGGSLYAATVGSGVFGAVAHNGAATAATIGAITIPWIKRSKASGETAAIVLGGNAGVGAVFPFSGAYFLLLAAPTVMGKLDAEGMVLTMFVAALWMVAIRIVIAAVMIRRRDVGAMDPEDVKPLRDTFSRGWSSLLVLAAVAIPIVATSGTLVTSIVGAEAADAVPVLVWLPVALLLPGLVVGRKSLPRTGRAWWSLLGDSSPKLGVVGVTMVAAFSASEAVSSLGLSEQLTPLLQGLGHLPAWLVAVIVGVVVIVVAGPLSTTATIAAVGGVAFAALTAVGVPEYAAFAALLVWGASESASPPGAAPLYVAAGIANVDPVRTFMPVIGYYLIPTFLLGVLMAVGVAWVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWJ4</accession>
    <name>D3PWJ4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3554"/>
    <dbReference type="EnsemblBacteria" id="ADD43216">
        <property type="protein sequence ID" value="ADD43216"/>
        <property type="gene ID" value="Snas_3554"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3554"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_3_0_11"/>
    <dbReference type="OMA" id="YMSISVD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="29"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="215" mass="23433" checksum="1B7693BE1BF309E3" modified="2010-04-20" version="1">MVLAAMSFGFGFRLRGMNDITSPDSSRTTIRLHMSMSLDGFIAGPDDQPGQELGRDGGRLFNWLDDRHGDGPSGQVYGEVLATGAVISGRRTFELAGRWNGDHHDGVPIFVLTNHVDPDDVPPGSAQFVTDVTECAELARTAAGDRVVMVHGAGAAQSLLRAGQLDEIDIHLVSVLLGEGRRLFDALGSQHIELERVRVVEARDVTHLRYRVRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWY1</accession>
    <name>D3PWY1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2OG-Fe(II) oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5574</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Antibiotic biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5574"/>
    <dbReference type="EnsemblBacteria" id="ADD45205">
        <property type="protein sequence ID" value="ADD45205"/>
        <property type="gene ID" value="Snas_5574"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5574"/>
    <dbReference type="eggNOG" id="COG3491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010119_6_3_11"/>
    <dbReference type="OMA" id="DGNSVMR"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0045">Antibiotic biosynthesis</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="4">
        <location>
            <begin position="179"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="321" mass="35631" checksum="39E4719F032CBC96" modified="2010-04-20" version="1">MTTTDFVPVIDISQRTDARERARLAEAIGRACENSGFYVIVGHGIPGELIDTMFSVTESFFTLPDSEKDAVANRPGVSGLRRSVGTTANSLGQRTPPDLCETFGVHVTGDLDDAERENLGDYWASWKLANVWPRRPQEFEPTWRAYLYSVEELAEDLMRLSALALGLAENYYEDKFDNHVSSLVANYYYPQTQKPLPGQLRLGAHTDFGGLTVLYQETDRGGLQVRRGDDDWRDVPAIPGSFVVNIGDLMAMWTGGRWVSTMHRVVNPQDGDTASRISIPFFFQPNHDAVIAPLGETADQGVIAGEWMAAKMRKIVPADRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX44</accession>
    <name>D3PX44_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5638</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020839.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5638"/>
    <dbReference type="EnsemblBacteria" id="ADD45268">
        <property type="protein sequence ID" value="ADD45268"/>
        <property type="gene ID" value="Snas_5638"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5638"/>
    <dbReference type="eggNOG" id="COG3154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070584_1_0_11"/>
    <dbReference type="OMA" id="AWNWAPQ"/>
    <dbReference type="OrthoDB" id="1713977at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010872">
        <property type="entry name" value="MDMPI_C-term_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07398">
        <property type="entry name" value="MDMPI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="2">
        <location>
            <begin position="14"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="MDMPI_C" evidence="1">
        <location>
            <begin position="147"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="249" mass="27927" checksum="3D54C28084D14132" modified="2010-04-20" version="1">MTRWDKNAFLMAWRADSDRLREAAVADELDREVPSCPGWSLRDLVAHVARVFLNYERLVTATAAPPADSKGDGDFDLGEDVLAEYDTAVRKLTTTLDGVRLDDPAWVPGPHARIARFWIRRLMCETAVHRWDAQMAFAAAEPIGSRAAAEGIQEVFDTFIPWGRRREESTATGVVQLFARDIDRHWFVRLREGRETLLDPDSVDVDNTAIQASASGNASDLYLALWGRVQTSVLELAGDETLFKALRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX73</accession>
    <name>D3PX73_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1633</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016907.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1633"/>
    <dbReference type="EnsemblBacteria" id="ADD41336">
        <property type="protein sequence ID" value="ADD41336"/>
        <property type="gene ID" value="Snas_1633"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1633"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="DNMVLTV"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="11"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="503" mass="52186" checksum="AF6698580109FB33" modified="2010-04-20" version="1">MTTKNPRRWWILGALCLSLLVLTIDNMILTLAIPALMSDLGASPASVQWILDAYILVFAGALLTAGSMSDRFGRRRFLNIGLSILGVASLLAAFAEEPWQVVACRAVMGLGAAIAMPSTLSILINVFEDDERRKAMSIWGMVSMLGIVLGPAAGGLLLEHFGWASAFLINVPLAIIGIISAVILIPESKGPARPSDPVGAVLSVAGMAALVFALIQIPHEGWSNRVVAAAVAAVVILAVFVVWELKREYPMLPLGIFRSRDFTGASLACVLIVFTNGAVMLALTQYLQLVLGFSPMTSALAFAPMAVVVGIVNPLAATVGKHISNKTLTVVGLLVIAGSFVILSMTGPEDGYGWLILGLVTVGVGTGLTTPAVYATLTSAIPPEHAGVGSAVNDTIQQGGMALGVAALGSVLSSAYTDALPSDVPEAARGSLTDALALAERTGATDLVRVARDAFLESQSTVFTVAAAMSVLGAVFALIVLRRKTSGPVEEASAEAELETSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX93</accession>
    <name>D3PX93_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016927.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1654"/>
    <dbReference type="EnsemblBacteria" id="ADD41356">
        <property type="protein sequence ID" value="ADD41356"/>
        <property type="gene ID" value="Snas_1654"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1654"/>
    <dbReference type="eggNOG" id="ENOG5033SAN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_943070_0_0_11"/>
    <dbReference type="OMA" id="ETWIEAQ"/>
    <dbReference type="OrthoDB" id="1642870at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048663" evidence="1">
        <location>
            <begin position="32"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="334" mass="35580" checksum="2A74207C65EE11AA" modified="2010-04-20" version="1">MRRAVTRLAAVATVLVTVPLAVLWASTTASSETTRGAPAYEYPVTRHADTSKPIPGVSVDISADKGQAVYLWARDLAAENVTPLGSGDNIGTTFSLECRHRDGTALDGERGTYWAANLVPPGEKKLTATLRWTFVAPAAGDYTCEVLVTSYSTIIVDGREVTMRVPAGASLAHRVYPASQRWTLPAESERTVKAGQSVTTLGFTYRPTTSEPKLAVVQDTNLTTCKAGSSICDGGSPGNSGSKVTTQVVAKLLNEDGTACGADLKSPAKNGYISTAKHHWTSTNTLYIEKSQLGNCPRLRLSLSLRVTEGNPVVIHAGFSVYRARTHGTAFEYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXF9</accession>
    <name>D3PXF9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidoglycan-binding domain 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1724</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016993.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1724"/>
    <dbReference type="EnsemblBacteria" id="ADD41422">
        <property type="protein sequence ID" value="ADD41422"/>
        <property type="gene ID" value="Snas_1724"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1724"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1414406_0_0_11"/>
    <dbReference type="OrthoDB" id="2025306at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049322" evidence="1">
        <location>
            <begin position="32"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="74"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="198" mass="21261" checksum="C34ED0233EC06397" modified="2010-04-20" version="1">MRNRKWKIAAGIGAAALIVGGVAGVAGLANADPTAKSTTFVDGFGNINDDWSDNHREAGVLCDGCDNSQGTDLVHLWQAILAADGYLTDEQIDGYFGPATAKATKQWKADRGLTANGRVGNGSWTLADDYLEPDPELGDEYPIYNGETDGNVQFGRATDATGAYRMNVVVTSEGYEMFNSSYEQGVQLFEETVTWTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXR3</accession>
    <name>D3PXR3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chorismate binding-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3736"/>
    <dbReference type="EnsemblBacteria" id="ADD43393">
        <property type="protein sequence ID" value="ADD43393"/>
        <property type="gene ID" value="Snas_3736"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3736"/>
    <dbReference type="eggNOG" id="COG0147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006493_1_0_11"/>
    <dbReference type="OMA" id="YQANLCR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate_bind" evidence="1">
        <location>
            <begin position="105"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="369" mass="38022" checksum="97BCE75D4D17B6D7" modified="2010-04-20" version="1">MQWRVGDGGDPAQLLRDFCEESGLDVADLSRSGVHDVSRRLCGVAVLVSAAAGAVMIGGEPGPPSPATAVPDLAAVAYHHAPVATSRPVGGFALTGEWEQSWTPAQHAAAVSAVRAAIGRGDVYQVNIVGHQSAPVSGDADGVVRRLASWPQARFGGTMSGPGWTVASASPECLAEVASGVVTTAPIKGTAPATVEGARQLRRSVKERAEHVMIVDLERNDLAHVAVPGSIAVEELFALREWGGLWQAESVIRARLAEGTGLDRLLRGLCPPGSVTGTPKLAALEHIADLEVVGRGPAMGAMGYVTGEGLRLGLTIRTVAVAESRLHVWAGGGITWRSDPNEEVAEAAAKATPITAALASYTSALTANT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXS6</accession>
    <name>D3PXS6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018977.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3749"/>
    <dbReference type="EnsemblBacteria" id="ADD43406">
        <property type="protein sequence ID" value="ADD43406"/>
        <property type="gene ID" value="Snas_3749"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3749"/>
    <dbReference type="eggNOG" id="COG1938">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055821_0_1_11"/>
    <dbReference type="OMA" id="MGVPHTR"/>
    <dbReference type="OrthoDB" id="605198at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008492">
        <property type="entry name" value="DUF774"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019151">
        <property type="entry name" value="Proteasome_assmbl_chaperone_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038389">
        <property type="entry name" value="PSMG2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09754">
        <property type="entry name" value="PAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028754">
        <property type="entry name" value="UCP028754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="301" mass="33337" checksum="DFE9D53D40A33526" modified="2010-04-20" version="1">MPNGEDLYTVEADTPDISGAVMLVELRGFMDAGQAGQGVTEYLLKELDHQVVASFDVDELIDYRGRRPVMTFDTDHWVDYDAPRLRVYLMRDDVGVPFLLLSGDEPDLRWERFAEAVQSLIEKFGIRLTVALHGIPMGAPHTRPLGVTAHGTDASLLPSGERTLNRLQVPGNAAALLELRLGQAGHDAIGFAVHVPHYLAQASYPNASVRLLESLHQATGLSVSVESLREEGRVVDAEVDSQVRASQEVSDVVAALERQYDMFDDSRPSLLVEESEEELPTGDELGEQFERFLAEQQRRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXY9</accession>
    <name>D3PXY9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020889.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45318">
        <property type="protein sequence ID" value="ADD45318"/>
        <property type="gene ID" value="Snas_5688"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5688"/>
    <dbReference type="eggNOG" id="ENOG502ZDIF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_185378_0_0_11"/>
    <dbReference type="OrthoDB" id="2092783at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="76" mass="8465" checksum="D787C5F5A224C98B" modified="2010-04-20" version="1">MDNLCPHCGWPDAEPYQVISRRLTRDSTQLSWVRCACGSLQMRQQPRGGEVSVLTRGRPTSDMSNLGNGHSELPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY92</accession>
    <name>D3PY92_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1761</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1761"/>
    <dbReference type="ESTHER" id="stanl-d3py92">
        <property type="family name" value="Proline_iminopeptidase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41459">
        <property type="protein sequence ID" value="ADD41459"/>
        <property type="gene ID" value="Snas_1761"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1761"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_4_11"/>
    <dbReference type="OMA" id="GDGPWTW"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="23"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="300" mass="32497" checksum="1907BFFF0B0DC039" modified="2010-04-20" version="1">MSDMTIHSGSVPIATRDHGGDGPPVLLLHGGGGNLLGWRDFPNRLTPAHRVVSFDLRGHGHSGDGDWDTASLLADIRAVADHFGFDEPALVGHSLGGMLSALWARDNPGCPAAVSIDGHRSAATHEHNYDGLDPETLRADLKAITEVFDAQTAALERPVPPEQLEAMRAMRSPDEGEAVFEARLQRDLVERDGQTYSRLGADTARLLRVMPEFVDAVPVLNDVAVPFLMLLATRDFPGLPPQFGPLMAAHRAGLRRDLATVRQTRPNLEVTEVDGSHGMVSERPDEVAALVLDFLARDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYA4</accession>
    <name>D3PYA4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1774</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017042.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1774"/>
    <dbReference type="EnsemblBacteria" id="ADD41471">
        <property type="protein sequence ID" value="ADD41471"/>
        <property type="gene ID" value="Snas_1774"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1774"/>
    <dbReference type="eggNOG" id="COG1135">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_3_11"/>
    <dbReference type="OMA" id="VIRKICH"/>
    <dbReference type="OrthoDB" id="1058434at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033232">
        <property type="term" value="F:ABC-type D-methionine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026253">
        <property type="entry name" value="ABC_MetN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018449">
        <property type="entry name" value="NIL_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43166:SF5">
        <property type="entry name" value="PTHR43166:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09383">
        <property type="entry name" value="NIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00930">
        <property type="entry name" value="NIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="320" mass="34029" checksum="6FB165DDE5D72229" modified="2010-04-20" version="1">MISLSKVSKRFGSTRAVDDVSLDVPAATIHGVLGRSGAGKSTLLRVVNLLEPPDSGTVTVAGRDLGTLTPAGLRDARARIGMVFQHFHLLHNRTVAANVELPLKLHRVERGERQRRVAELLELVGLSDQARKFPAQLSGGQRQRVAIARALALRPDVLLSDEATSALDPGTTVEILDLFVKLRDTLGLTILLITHELDVITRICDSASVMRDGKVVEHGPVAELLATPGSDLADQAFRLAAPGEGGGINVEVTFTGSAVGEPVLAALVRHFDVDASITDASVHTVAQGTVGRLRLRLPQSAASEKAAAWLSEQGYGVRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYM7</accession>
    <name>D3PYM7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Pyruvate kinase</fullName>
            <ecNumber evidence="4 12">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Snas_3804</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="4 12"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3804"/>
    <dbReference type="EnsemblBacteria" id="ADD43460">
        <property type="protein sequence ID" value="ADD43460"/>
        <property type="gene ID" value="Snas_3804"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3804"/>
    <dbReference type="eggNOG" id="COG0469">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015439_0_2_11"/>
    <dbReference type="OMA" id="QVPIVQK"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PTHR11817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="SSF52935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 12 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 15" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PK" evidence="13">
        <location>
            <begin position="6"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="PK_C" evidence="14">
        <location>
            <begin position="356"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD43460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="476" mass="50760" checksum="9AA16452413E8B03" modified="2010-04-20" version="1">MPIVTRRAKIVCTLGPATSTPDRIRGLVEAGMNVARLNFSHGTHADHESMYHMVRQAAADANAAVGILADLQGPKIRLGKFEEGKAEWNTGDHVSLTSEDVPGTAKRVSVTYTKLPEEVKGGDRLLVDDGRLVLEVLDVDGDDINCLVIEGGPVSNHKGLSLPNVAISVPALSEKDTEDLRFALRLGVDLVALSFVRDPADVDPVHAIMTELDVRRPVLAKIEKPEAVSRLEAIVDAFDGIMVARGDLGVELPLEQVPLVQKRAVQMCRENAKPVIVATQMLDSMINNARPTRAETSDVANAILDGADAVMLSGETSVGKYPIGTVRTMASIVTTTEAGSFTVPKLEHDPKTQGGALTSAASKVARAVDAKALVAFSQTGDTVRRLARLHCPLPLLAFTPEPKTRGQLALSWGVESHEVAYVDHTDDMFDQVDQAVFSLGKANVGDLVVIVAGSPPGTPGSTNTLRVHRIGETDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYR6</accession>
    <name>D3PYR6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FtsX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3843</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019070.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3843"/>
    <dbReference type="EnsemblBacteria" id="ADD43499">
        <property type="protein sequence ID" value="ADD43499"/>
        <property type="gene ID" value="Snas_3843"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3843"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021084_0_0_11"/>
    <dbReference type="OMA" id="WQTAIPI"/>
    <dbReference type="OrthoDB" id="1195369at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="647"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="695"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="739"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="239"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="770" mass="82870" checksum="BF2A99B80391AB00" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYS3</accession>
    <name>D3PYS3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proton-translocating NAD(P)(+) transhydrogenase</fullName>
            <ecNumber evidence="3">7.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Snas_3850</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019077.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3850"/>
    <dbReference type="EnsemblBacteria" id="ADD43506">
        <property type="protein sequence ID" value="ADD43506"/>
        <property type="gene ID" value="Snas_3850"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3850"/>
    <dbReference type="eggNOG" id="COG3288">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137885_1_1_11"/>
    <dbReference type="OMA" id="FVVTDRM"/>
    <dbReference type="OrthoDB" id="1933548at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024605">
        <property type="entry name" value="NADP_transhyd_a_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12769">
        <property type="entry name" value="PNTB_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="PNTB_4TM" evidence="11">
        <location>
            <begin position="9"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD43506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="102" mass="10582" checksum="756630C73EB9F70F" modified="2010-04-20" version="1">MELDLLTAVTVFVLGVLVGFEVISKVPATLHTPLMSGANSIHGIVVIGAMLITATADGFLGYLLAFLAVAFGFANVVGGYVVTDRMLHMFKARPAAKEGSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYX1</accession>
    <name>D3PYX1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_3899</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019125.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3899"/>
    <dbReference type="EnsemblBacteria" id="ADD43554">
        <property type="protein sequence ID" value="ADD43554"/>
        <property type="gene ID" value="Snas_3899"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3899"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_2_11"/>
    <dbReference type="OMA" id="QWEKDGI"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="123"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="230"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD43554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="380" mass="42263" checksum="C7FCD85749F1543D" modified="2010-04-20" version="1">MRRDIFTDEHDAFRETARTFAEREIVPHHGQWEEDGLVPRELWTAAGRQGLLCVDLPEKYGGAGLDDFRYHAIVAEELARSRATGVGFVVHNDMAVPYLSRLATEEQKDRWFSGLCAGELIAAIAMSEPGAGSDLQGIATTAVRDGEDYVLNGQKTFITNGIHADLVIVLARTDPEAAHLGFSLFAVERGMEGFERGRKLDKIGMRAQDTAELFFNDVRIPAANLVGEEGKGFIYLMEGLPRERLAIAVVGQAGAEAVFDETVEYVRGRKAFGRNIGKFQHVRMTMAEMKTELHIGRTFVDQCMLALNAGELDVTEAAMSKWWITEMQKRVTDQCLQLHGGYGYMSEYPIAQAYLDTRAQTIYGGTTEIMKEIIGRSLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYZ9</accession>
    <name>D3PYZ9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5798</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020999.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5798"/>
    <dbReference type="EnsemblBacteria" id="ADD45428">
        <property type="protein sequence ID" value="ADD45428"/>
        <property type="gene ID" value="Snas_5798"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5798"/>
    <dbReference type="eggNOG" id="COG3226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_21_0_11"/>
    <dbReference type="OMA" id="NEARRTQ"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041583">
        <property type="entry name" value="TetR_C_31"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17940">
        <property type="entry name" value="TetR_C_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="188" mass="20800" checksum="17E3DF81B2F5F143" modified="2010-04-20" version="1">MVSNPRRRTALLDAAVEVLAAQGARGLTFRAVDTEAGVPVGTASNYFSGRDELLRQAAEYVFVRLSPPAEEYQPPPGEGLELLIAQMREITERARVDRAGYLALFELRLEAARRPDLRDFFTERFRVNLDNIIAGYETWQRRGDRVTPVLLYLAMTGLLLEDLTLPGVLAGEGDGDLVTRLVAAIAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ21</accession>
    <name>D3PZ21_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Septum formation initiator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5820"/>
    <dbReference type="EnsemblBacteria" id="ADD45450">
        <property type="protein sequence ID" value="ADD45450"/>
        <property type="gene ID" value="Snas_5820"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5820"/>
    <dbReference type="eggNOG" id="COG2919">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085342_3_1_11"/>
    <dbReference type="OMA" id="IPYQVQL"/>
    <dbReference type="OrthoDB" id="1711819at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007060">
        <property type="entry name" value="FtsL/DivIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04977">
        <property type="entry name" value="DivIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="120" mass="13482" checksum="357B221F4F7CF5E2" modified="2010-04-20" version="1">MSGRTAVIALVLSALALSYAYPVRTYLEQRAEINRLRDSQGEQAQRIAELEAERAKWDDPAYVKAQARERLLLVEPGEELIIIVDDKPDKGDKDSGPSKSSKDPWFDDLWESFDNADNSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZG5</accession>
    <name>D3PZG5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017210.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1943"/>
    <dbReference type="EnsemblBacteria" id="ADD41639">
        <property type="protein sequence ID" value="ADD41639"/>
        <property type="gene ID" value="Snas_1943"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1943"/>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065741_0_0_11"/>
    <dbReference type="OMA" id="QCHFGQD"/>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="60"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="268" mass="29676" checksum="179B622D7F8F7633" modified="2010-04-20" version="1">MDTTPDYRVVNAANWDERVPIHLASDFYDLDGFRQRRDSLNDYERAEMGDVDGKSLVHLQCHFGRDTLSWAKYGATVAGVDFSALAIEAARELAAELGIDASFVTADVYDAAEALGGRTFDIVYTGIGALCWLPDLTRWAETVARLLVPGGFLYLTEFHPVVDALDGKTGTHVDKDYFDTEPSVYDETPTYTDGGENLANGTTVEFHHTLGDIITALAAAGLRIEWLREHDFTLFQQFAGLRRRDDGTFVYEGTGRAPLMFSVKATRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZH1</accession>
    <name>D3PZH1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017216.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1949"/>
    <dbReference type="EnsemblBacteria" id="ADD41645">
        <property type="protein sequence ID" value="ADD41645"/>
        <property type="gene ID" value="Snas_1949"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1949"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131959_0_0_11"/>
    <dbReference type="OMA" id="YFERCWP"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="112" mass="12921" checksum="67B21519663A33C0" modified="2010-04-20" version="1">MSNTDVVRAMFDNYRAQNREATEALLAEDFEFTSPNDDHIDKAAYLEHCFPTAHRFVTQALLDVVEASTDGVFARYEYELTDGERYRNTEHFTVRDGRIRAVEVYFGGKFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZI6</accession>
    <name>D3PZI6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="1">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoribosyl pyrophosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_1964</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.6.1" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017231.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1964"/>
    <dbReference type="EnsemblBacteria" id="ADD41660">
        <property type="protein sequence ID" value="ADD41660"/>
        <property type="gene ID" value="Snas_1964"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1964"/>
    <dbReference type="eggNOG" id="COG0462">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033546_4_0_11"/>
    <dbReference type="OMA" id="HYAYARS"/>
    <dbReference type="OrthoDB" id="1011035at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD41660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="314" mass="34074" checksum="E36C66E2CE861EB8" modified="2010-04-20" version="1">MRDDELVVLGGSASPLLTKEICRILQVPVGEGEVHQFSDGNLFVKIGQNVRGRHVYLVQSTVFPANDHFMELLFWVDALKRASAASVTVIIPYFSYAKGDKKDEPRVSIRARVCAQSIEAAGADRVVTLDLHAPQIQGFFGVPVDDLYGEPVLSDAIAAEKLDDLVIVSPDAGFAKKAKQYAKRLGAPLAIADKERIDHTESARIADLIGDVDGRNAVIVDDFTITAGTLAEVADTLIEKGARSVRAAVTHGVFTEKAMPRLDASAIETLWCTDTVENRPAELSPRVSTVSVAPLFAEAIRRIHNRESLSVLFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZM4</accession>
    <name>D3PZM4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019132.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43561">
        <property type="protein sequence ID" value="ADD43561"/>
        <property type="gene ID" value="Snas_3906"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3906"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_2_4_11"/>
    <dbReference type="OMA" id="WHMRMAQ"/>
    <dbReference type="OrthoDB" id="1681849at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="140" mass="15825" checksum="0C71AD80F8F906EF" modified="2010-04-20" version="1">MSRARGWRRLAALHARIEDRIERAMQATHDLSVNEYCVLHLLSEQEMEGRHYRMQAIAEAIVLSQSATTRLVNRLEDRDLVKRYLCPDDRRGIYADITETGIAVHAAAAPTHDEALEAALIEASAEPEYADLVKSLDELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZV2</accession>
    <name>D3PZV2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019210.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3987"/>
    <dbReference type="EnsemblBacteria" id="ADD43639">
        <property type="protein sequence ID" value="ADD43639"/>
        <property type="gene ID" value="Snas_3987"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3987"/>
    <dbReference type="eggNOG" id="COG1234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031317_3_0_11"/>
    <dbReference type="OMA" id="NPCSGYL"/>
    <dbReference type="OrthoDB" id="1712770at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="23"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="257" mass="27061" checksum="C4676D8EE87D2A4D" modified="2010-04-20" version="1">MTTAGLRLNVLGSATPYPRPDNPCSGYLLTSGDTRIWLDAGTGTLAALQRHVRLTDLDAIWISHAHADHSADLLTAYYALLYADLRLTAPLPLYGPPGIADRLADFLTNGPERSPVERAFTIHELHDGHRAEIGPLSLTTRAVEHGLPAFAVRVDDGDVSLVYSGDTAPCAKLTELATTCDTLLCEADSAEPSTPPVHHTPEDAGTTATAAGVGRLIITHVGPFLTPEQAVDRAAATFSGPIGYAAPGTTIDITPMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZW3</accession>
    <name>D3PZW3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019221.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3998"/>
    <dbReference type="EnsemblBacteria" id="ADD43650">
        <property type="protein sequence ID" value="ADD43650"/>
        <property type="gene ID" value="Snas_3998"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3998"/>
    <dbReference type="eggNOG" id="ENOG5033AGQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1097987_0_0_11"/>
    <dbReference type="OrthoDB" id="1967418at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021213">
        <property type="entry name" value="DUF2567"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10821">
        <property type="entry name" value="DUF2567"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="253" mass="27838" checksum="E08987AF10952A48" modified="2010-04-20" version="1">MTSSERSRDESDTIELAPAAAGASDVAPDPFDDPDESRLSRMWRRGSRRRRDLLAATGIVALLTVLGFPLGALWNLLAPRVEMVRVDGGWAFTEENPEQYMGDDGVFALLGLGAGITVALVLWLGWRSRRGPLMLTGLVLGSILCQTVAWRFGRFGRDDYLNSLDSVRVGWHTWRAPDLLMVDFHPFGTGEPGKIDTAWEAMVRGDLAGMWDHLSLGVLATMGFAAAFIYTVCAGWSKYASLRAERLPGEDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q041</accession>
    <name>D3Q041_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_5943</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5943"/>
    <dbReference type="EnsemblBacteria" id="ADD45570">
        <property type="protein sequence ID" value="ADD45570"/>
        <property type="gene ID" value="Snas_5943"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5943"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_8_0_11"/>
    <dbReference type="OMA" id="GSLYRIR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="56"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="331"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD45570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="425" mass="43684" checksum="EA202FF90C43D3D0" modified="2010-04-20" version="1">MTVDETAPPPNRDSASGEAEPVVADPDEALTPARLRPRDIVRVGAVGLRTRPLRAFLSALGIAIGIAAMVCVVGISSSSQAELDRTLSALGTNLLSVTPGSTLTGETSELPLEAEDMIARMDGVQEVSAVGKVADTQVYRSEKIDRNDTGGITPYAARLDLPDVLGATMRDGTWLNAATAKFPATVLGSSAAERLGIGEADLGTQVVIGGQRFTVVGILDPIALAPDLDNAVMVGWPVAKAELGFDGHATEVHTRSDESKLEAVRSILGATANPQAPNEVEVSRPSDALAAKQATNQAFTSLLLGLGAVALLVGGVGVANTMVISVLERRPEIGLRRSLGATRGQIRAQFIVESLLLSLLGGVSGLILGLGVTTGYALSQGWPPIVPSWASGLGLAATVLIGAVAGLYPAVRASRLPPTEALAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q069</accession>
    <name>D3Q069_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH dehydrogenase (Ubiquinone) 30 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021169.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5971"/>
    <dbReference type="EnsemblBacteria" id="ADD45598">
        <property type="protein sequence ID" value="ADD45598"/>
        <property type="gene ID" value="Snas_5971"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5971"/>
    <dbReference type="eggNOG" id="COG0852">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042628_1_1_11"/>
    <dbReference type="OMA" id="PPEFEGH"/>
    <dbReference type="OrthoDB" id="1735902at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="SSF143243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Complex1_30kDa" evidence="2">
        <location>
            <begin position="24"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="22172" checksum="8B0E0AE186283E32" modified="2010-04-20" version="1">MWTEDIAAALPDAEVSADEPRPTVTVAPGGWHAAVLTARDRLGLDFFDWLSAVDEGEGAYRVVTHLWSIAGRRGLLLNTVTSSGAVDSIVDVYPGASWHERETHEMFGLDFGGHPDLAPLLLAPEFEGHPLRKDFVLASRVAKPWPGAKEPGGDGPRKRQPMRPPGVPAPGEWGPPLPEAETDGDTEATPARPARKTARPPRKDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q093</accession>
    <name>D3Q093_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5996</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021193.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45622">
        <property type="protein sequence ID" value="ADD45622"/>
        <property type="gene ID" value="Snas_5996"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5996"/>
    <dbReference type="eggNOG" id="ENOG5033X8U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_885406_0_0_11"/>
    <dbReference type="OMA" id="CAIFRDD"/>
    <dbReference type="OrthoDB" id="2128865at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="314" mass="33845" checksum="277AD01B184B0D89" modified="2010-04-20" version="1">MTTPDPVSDETPQADPDGTPRVDQDSPPLIAPANRPRAILILVIGLAALVWFCSGMPFDDTPPHLSTPSPESTDTVPPDAPPTDKPSDDGEVRIVEKGYQPLVDVAGEPQVSWGAMVENTSEEMVAVVTLKLAILDGDGKSLNKEHGDYDLDPTVPVILPGQRVGIGDVVYMDSSGVAKVKLDVADVRWYPVDGQTGAFAELKVSKVKGSWVNQGQEVPYWGDDEIGAYADERGDLLLRFRVDSGYERIVERPGGCAIFRDDNGKIVGASPLEALNLRAEIPPGWSKQHLIVTDGPPENFDASATKVYVYPKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0C7</accession>
    <name>D3Q0C7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015362.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0069"/>
    <dbReference type="EnsemblBacteria" id="ADD39791">
        <property type="protein sequence ID" value="ADD39791"/>
        <property type="gene ID" value="Snas_0069"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0069"/>
    <dbReference type="HOGENOM" id="CLU_2182343_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="109" mass="11516" checksum="6EE8DB3347B375AB" modified="2010-04-20" version="1">MADDIEVVLTNLNRIARNELPPIITNTSTASQEIKSGLEGIEPAFDGDVFGPTLEAFQSTVTSVCAELDKANERVKDTVHAVIEVLGAYRAVDGANARSITATTSPVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0N7</accession>
    <name>D3Q0N7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2079</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017344.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2079"/>
    <dbReference type="EnsemblBacteria" id="ADD41773">
        <property type="protein sequence ID" value="ADD41773"/>
        <property type="gene ID" value="Snas_2079"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2079"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="PERHEEM"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03793">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00740">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51178">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="11"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="6">
        <location>
            <begin position="422"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="298"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="361"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="361"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="388"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="503" mass="53132" checksum="431EC82935357141" modified="2010-04-20" version="1">MDNIRILGNRYRLDERVDGGGMGDVWRGRDIRLDRTVAIKVLHAGLSGDPAFRERFHGEARAVAALSAPGVVNLFDYGEDASADAGVVSYLVMEYVPGRSLRTVLSERGSLRVDEVLDIVAQSAEALDVAHEAGIIHRDIKPGNILIDAETGVVKIVDFGIARTRGQSSLTETGVVMGSVCYVSPEQLYGHEPSGSSDVYSLGVVAYEALTGRKPFASDVPATVIHEQIHKAPPPLPETVPAGVREAIMRALAKEPRHRWPNAAAFAAACRELIGAAAPREDATVRVAADAVPTTVIPTPQPTTVRAAAGPRPVTPTSGARRNRGAVVSHRRSGLRPRTLVVTTAIVALLAAGGIAAARPWDDERKRPAEGKGSTVADDRDETTAATTDSDKAPSPSEEQPSSQSSSHSPSETPSTSSPSEKPEEGKVPSLMGLSEDEAYAKAEAKGFTNVAAYEVGSGEYACTVVEQNPSAGSSQELDEELSFGVEYGDTPDCETDSSPEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q121</accession>
    <name>D3Q121_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome aa3 subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_4120</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019342.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4120"/>
    <dbReference type="EnsemblBacteria" id="ADD43771">
        <property type="protein sequence ID" value="ADD43771"/>
        <property type="gene ID" value="Snas_4120"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4120"/>
    <dbReference type="eggNOG" id="COG1845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044071_1_1_11"/>
    <dbReference type="OMA" id="SIYWWGS"/>
    <dbReference type="OrthoDB" id="1502742at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="PTHR11403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="SSF81452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="COX3" evidence="9">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="200" mass="22617" checksum="1608E1FB9A4FCB7D" modified="2010-04-20" version="1">MTAAEATIDPRRIHSLTRPNMVSVGTIVWLSSELMFFAALFAMYFSIRAAAPELWEEHTKHLNIPYAAVFTLILVASSFTCQMGVFCAERGDVYGLRRWFTITFLMGLVFVLGQVNEYRTLVSEGIAINTDGYGTMFYLTTGFHGLHVTGGLIAFIIYLIRTTMGRFTPAQATSAIVVSYYWHFVDVVWIALFAMIYFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q179</accession>
    <name>D3Q179_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021230.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6035"/>
    <dbReference type="EnsemblBacteria" id="ADD45659">
        <property type="protein sequence ID" value="ADD45659"/>
        <property type="gene ID" value="Snas_6035"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6035"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_25_6_11"/>
    <dbReference type="OMA" id="VSHPELM"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16859">
        <property type="entry name" value="TetR_C_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="22484" checksum="48BDA71265196CD0" modified="2010-04-20" version="1">MTAPKTDGPGRPRDPAADKAILRAAIDLLVERGVDQTSIEQIAKRAGVAKVTVYRRWRTKEDLFAQAIETARQDIPNTADADRPSEALPQVIADLLPRWGQVLAEPRFRALTARLLGAGPSHPKLLDAYRRHHVQPRRELARAAMIQAQADGVLSPSADVDMLIDMMTGAIMQHLLLEPEPLHPKDISDYLRRLLQQAGFTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q190</accession>
    <name>D3Q190_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021241.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6046"/>
    <dbReference type="EnsemblBacteria" id="ADD45670">
        <property type="protein sequence ID" value="ADD45670"/>
        <property type="gene ID" value="Snas_6046"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6046"/>
    <dbReference type="HOGENOM" id="CLU_782816_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="354" mass="38449" checksum="BCB0334E0DA7F7C9" modified="2010-04-20" version="1">MYGPEELKEKAEKIHKLAMEVTFKSSAQRDSDHNTRDAVKHANGEPCGGDDVAIGPGPICYDSDKASVSGYYRQYTDQILEHIRPYPAELDALVKSVKQVEHRLGVADGTIKMVAPGSSSDSFPGLLDATMDDHMDSMEAHVRDWNGLFAENLRHAVVNPIDVIHKNNVFALNVFTQATEAIYLVNLRKRQTLTGIVDEVISALNEAKNTLDFLDGDELKTAIFVAGAAVAIGTATIANPPLGVAIGSATLGVVVGLAKDELPKKESLDFMSETPAHVIEKMGTALKKMHDEYEKSLAEITSTLRENVGMMEKALQAPNDDYGFTLFTIPRPSIVGEPGSPPSADTIRTSMWPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1R0</accession>
    <name>D3Q1R0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015479.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0189"/>
    <dbReference type="EnsemblBacteria" id="ADD39908">
        <property type="protein sequence ID" value="ADD39908"/>
        <property type="gene ID" value="Snas_0189"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0189"/>
    <dbReference type="eggNOG" id="COG2211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_13_2_11"/>
    <dbReference type="OMA" id="RCIVMIL"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="426" mass="45595" checksum="4CFDF7DACF5E5CB8" modified="2010-04-20" version="1">MTSRTENVTFRFREERNYSRFFSGQSLSLLGDEISAMAIPLIAIQILDAGAFEQGLLFFSKFLPALLFGLHFGAIIDKFAKRSILVAADLARMLLLAVIVILWAVGLLSLPVFLVIAFGFGAFNVLATICGQAYIPKLVPEPKLLDANGKLQKVTTFAEVSGGSVAGAVVQVLTAPIALILDAISFLVSALFVAGVREPGHPPERAEHEKPRIWDGVTFILRNVRLRAITLCTATSNFFSAMMVSLYLLFAMNVLHFTPLMIGILLSVASCTALISGFFTERGTRHLGVRGSLIAGQLVMAAGCVVLPFAGGDTIVKSLLLVASHGIFVIGMIAFMTTQVTYRQQVTPENMQGRVHAGSYMLTYGAFALGALAGGVSGEYLGIRETLVIGALGHILAAAWLLPRSVRVTDGEPPTPAKEEAHDIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1R3</accession>
    <name>D3Q1R3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid adenylation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0192</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015482.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0192"/>
    <dbReference type="EnsemblBacteria" id="ADD39911">
        <property type="protein sequence ID" value="ADD39911"/>
        <property type="gene ID" value="Snas_0192"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0192"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_0_12_11"/>
    <dbReference type="OMA" id="CAPESIR"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1360"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1914" mass="209626" checksum="E204A72C29933230" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1X4</accession>
    <name>D3Q1X4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Phosphoenolpyruvate-protein phosphotransferase</fullName>
            <ecNumber evidence="5 13">2.7.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Phosphotransferase system, enzyme I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ordered locus">Snas_2147</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5 13"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017412.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2147"/>
    <dbReference type="EnsemblBacteria" id="ADD41841">
        <property type="protein sequence ID" value="ADD41841"/>
        <property type="gene ID" value="Snas_2147"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2147"/>
    <dbReference type="eggNOG" id="COG1080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007308_7_0_11"/>
    <dbReference type="OMA" id="MFPMISE"/>
    <dbReference type="OrthoDB" id="467393at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024692">
        <property type="entry name" value="PTS_EI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000732">
        <property type="entry name" value="PTS_enzyme_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="21" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="13 21" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PEP-utilisers_N" evidence="20">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="18">
        <location>
            <begin position="150"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="19">
        <location>
            <begin position="243"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="PEP binding" evidence="15">
        <location>
            <begin position="432"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="14">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="480"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR000732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF05524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ADD41841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="538" mass="55026" checksum="BC5FE57943DC719E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1X9</accession>
    <name>D3Q1X9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF418 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2152"/>
    <dbReference type="EnsemblBacteria" id="ADD41846">
        <property type="protein sequence ID" value="ADD41846"/>
        <property type="gene ID" value="Snas_2152"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2152"/>
    <dbReference type="eggNOG" id="COG2311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039610_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04235">
        <property type="entry name" value="DUF418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="DUF418" evidence="2">
        <location>
            <begin position="227"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="393" mass="41902" checksum="A025DEBA63FD94EA" modified="2010-04-20" version="1">MNNLPAARTLTETATPTRRILTPDLARGFMLLLIAMAYAPIYVTTGSVGGYGHRPGGSAIDHIVSFLTTLLLENRAFPMFGVLFGYGLVMLVNGAKRKGLTDAESKRILRRRSLWLIVFGTVHTLLAYSGEVLAAYGVAGLTIGWLLYRPTLKLGKALAILTPFYAVTVALMMVSAGATGSSSEPFIHPGYTTMGDWLTRIAAIVAGPLGNTFIFPMLLFVVIGIWAARKGLLERPHEHQVLLKRLAIVGISASVAGALPSALAGAGAFDVSDYGFGVLSTIQVLTGVFAGIGYTALFGLLGMRMERRQTTITKTLAAAGQRSMSVYLFISLSLALLMNYDLVGLGTQVHKAGAVVIAFLVWLVGVSLARTLALKGIPGPAETLLRSLIHRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q215</accession>
    <name>D3Q215_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2190"/>
    <dbReference type="EnsemblBacteria" id="ADD41882">
        <property type="protein sequence ID" value="ADD41882"/>
        <property type="gene ID" value="Snas_2190"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2190"/>
    <dbReference type="eggNOG" id="ENOG503161G">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148679_0_0_11"/>
    <dbReference type="OMA" id="YETDMEL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019592">
        <property type="entry name" value="DUF2469"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10611">
        <property type="entry name" value="DUF2469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="109" mass="13204" checksum="FB89A969C8AB9C21" modified="2010-04-20" version="1">MTLSAEDLEKYETEMELQLYREYRDIVRQFSYVVETERRFYLTNHVEMHVRNTDGETFFEVEMSDAWVWDMYRPARFVKNVRVMTFKDVNVEELDKPDIELPTEGGFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q222</accession>
    <name>D3Q222_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsB</name>
        <name evidence="7" type="ordered locus">Snas_2198</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017460.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2198"/>
    <dbReference type="EnsemblBacteria" id="ADD41889">
        <property type="protein sequence ID" value="ADD41889"/>
        <property type="gene ID" value="Snas_2198"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2198"/>
    <dbReference type="eggNOG" id="COG0052">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040318_2_2_11"/>
    <dbReference type="OMA" id="SYIDRAY"/>
    <dbReference type="OrthoDB" id="1623045at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="230"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="297" mass="32707" checksum="7A94C4FC24E6531A" modified="2010-04-20" version="1">MPVVSMRQLLESGVHFGHQTRRWNPKMKRFILTERNGIYVIDLRQTLDYIEKAYGFIKNTVAEGGSIMFVGTKKQAQEAIAEQAQRVGMPYVNYRWLGGMLTNFQTMFKRLQRLKELEILEQSGNAKEGRTKKELLQLMREKDKLARTLGGLRDMTKLPSAIWVVDTKKEHIAVDEARKLGIPVVAILDTNCDPDEVNFPVPGNDDAIRSAALLTRVVADAVADGLIARSSKSDKEEDKPGAAGGDAAEPLAEWEQELLKPTETGASEGAHAESAAEAKTEADTTVAEAEASGEVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q277</accession>
    <name>D3Q277_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4159"/>
    <dbReference type="EnsemblBacteria" id="ADD43810">
        <property type="protein sequence ID" value="ADD43810"/>
        <property type="gene ID" value="Snas_4159"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4159"/>
    <dbReference type="eggNOG" id="ENOG50333S1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_972901_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="288" mass="31150" checksum="9B9D5D6BA28A54C5" modified="2010-04-20" version="1">MTVSAADLANKGMEVRNKAVEKWMEEEAGIYASTELQTAVEGAFDYIVTMFEQMGLRDPKRLDTMSGYLADARTTLTEPVIGEIDTIKGQLDDWEGDAADNFIFDYLSPLTQINANQIYYIGVLENTLDGVKTMLEESRKNTIQLGDKTIEALDALEDTGEGMYALTIVAAVVGVVGAVVTGGASVALAVSFASISGAISIGAGAVTLEEQRVSGDDVEAVLNSMIDSYWDINDTNRIIEEDLAKLLGQDVDTVREQANRYRPIIPDISGYGSSPKDREILGEFQPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2M6</accession>
    <name>D3Q2M6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6154"/>
    <dbReference type="EnsemblBacteria" id="ADD45777">
        <property type="protein sequence ID" value="ADD45777"/>
        <property type="gene ID" value="Snas_6154"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6154"/>
    <dbReference type="HOGENOM" id="CLU_3189277_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="46" mass="4966" checksum="6C98F0ADEA5FFD41" modified="2010-04-20" version="1">MRIVKRVAATGIMLGIALVALSPDEPVSPLVMFTSGPHCSWRSSPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2R4</accession>
    <name>D3Q2R4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021386.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6192"/>
    <dbReference type="EnsemblBacteria" id="ADD45815">
        <property type="protein sequence ID" value="ADD45815"/>
        <property type="gene ID" value="Snas_6192"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6192"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_32_1_11"/>
    <dbReference type="OMA" id="VHFLYHR"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032962">
        <property type="entry name" value="HPA2/HPA3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10545:SF42">
        <property type="entry name" value="PTHR10545:SF42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="144" mass="16508" checksum="E5CB26CCB49B6911" modified="2010-04-20" version="1">MISIGKLTENDREAWEKLFTGYNTFYERTLPSEMMNRAWQAFQDDTRMHAFGAKLDGQLVGIVHFLTHASTTAFDVCYLQDLFTAPEARGKGVARALIDEVTAWARARECSRVYWSTHETNSTARKLYDQVAENKGFILYQIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2R8</accession>
    <name>D3Q2R8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021390.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6196"/>
    <dbReference type="EnsemblBacteria" id="ADD45819">
        <property type="protein sequence ID" value="ADD45819"/>
        <property type="gene ID" value="Snas_6196"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6196"/>
    <dbReference type="eggNOG" id="ENOG5032ZXS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2700907_0_0_11"/>
    <dbReference type="OMA" id="RWLSIAF"/>
    <dbReference type="OrthoDB" id="2038731at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="73" mass="8304" checksum="32A49D70C64D1191" modified="2010-04-20" version="1">MNWSNRIRQTHRWLAVFFTVTVVGTAVALSLPEPVVWVSYIPLLPLALMFFSGIFLFVHPYVAKRRGSAVAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2T5</accession>
    <name>D3Q2T5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021407.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6215"/>
    <dbReference type="EnsemblBacteria" id="ADD45836">
        <property type="protein sequence ID" value="ADD45836"/>
        <property type="gene ID" value="Snas_6215"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6215"/>
    <dbReference type="eggNOG" id="ENOG5033CMQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123281_2_1_11"/>
    <dbReference type="OMA" id="WAGARLW"/>
    <dbReference type="OrthoDB" id="2086273at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021517">
        <property type="entry name" value="DUF3180"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11377">
        <property type="entry name" value="DUF3180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="169" mass="17607" checksum="78DF3C79B87923D0" modified="2010-04-20" version="1">MNEGQQEPKQPTLKPTAPSTLLVAALAAGALILVLATVNYPPVPGWYTPTTLLLLALVLAYTAHTTRARIERKEGAKPVEPLLFARFAALAKASSVGGALIAGAYAGIVVYLVAHRYLAAAGRDLPLAVFGFVACLILVAAALWLERACRIPEDSEDDDQTSGGASANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2X7</accession>
    <name>D3Q2X7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015518.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0228"/>
    <dbReference type="EnsemblBacteria" id="ADD39947">
        <property type="protein sequence ID" value="ADD39947"/>
        <property type="gene ID" value="Snas_0228"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0228"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_5_1_11"/>
    <dbReference type="OMA" id="INNIAWL"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="9"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="255" mass="26888" checksum="BD7E3659E2982628" modified="2010-04-20" version="1">MSASILVTGGTGTLGRLVTPLLRDTGARLRVLSRGSRATEPGVEHVTGDLLKNEGLTAAVAGVDTILHLAGGAKGDAEATANLVRAAHRAGTVRHLVHISVIGADRMPLAWFANQRGAEQAVTESGLPWTMLRAAQFHDLVLTMVRGMSKLPLIPAPGGLRFQPVATADVASRLAELTLGDPAGLVPDLAGPTVYTLDELVRGYLSANGRRRLFLPIRIPGKAGRAYRAGHNLNLDTAVTGEHTWEDFLADRVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q302</accession>
    <name>D3Q302_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015543.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0254"/>
    <dbReference type="EnsemblBacteria" id="ADD39972">
        <property type="protein sequence ID" value="ADD39972"/>
        <property type="gene ID" value="Snas_0254"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0254"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_27_5_11"/>
    <dbReference type="OMA" id="WHEVRPE"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="23"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="166" mass="18755" checksum="71497B81FAD29C9C" modified="2010-04-20" version="1">MPDMMDEVQRLWHEVRPEADVGPMGVVGRIQRASRLLEQGHRDYFSRFDIDDGEFNVLATIRRYGPPYTVTPGKLTETSYIKAAAITNRVDRLVAKGYVTRETDPDNRRKVRVTLTSSGLDIVERAFDGHVTNEDRMLAALDGEEREQLAGLLRKLLESLGDVPKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q303</accession>
    <name>D3Q303_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015544.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0255"/>
    <dbReference type="EnsemblBacteria" id="ADD39973">
        <property type="protein sequence ID" value="ADD39973"/>
        <property type="gene ID" value="Snas_0255"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0255"/>
    <dbReference type="HOGENOM" id="CLU_2511082_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="85" mass="8825" checksum="FE32B7BBBC9835C3" modified="2010-04-20" version="1">MLGQLFVPKLVDGKRTSRVLALAALLWALGGGLGLQHLGGLWWLIGAGIGVLAAIGNLAAEPARERRLATATERGRPAAWSESGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q339</accession>
    <name>D3Q339_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015580.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0291"/>
    <dbReference type="EnsemblBacteria" id="ADD40009">
        <property type="protein sequence ID" value="ADD40009"/>
        <property type="gene ID" value="Snas_0291"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0291"/>
    <dbReference type="eggNOG" id="COG1167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_6_11"/>
    <dbReference type="OMA" id="WRKIYKH"/>
    <dbReference type="OrthoDB" id="1024978at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="5"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="363" mass="39025" checksum="6375EF8B6A9CB05C" modified="2010-04-20" version="1">MAPTDVISFSRGAPSLDIVDIEGLKAAAAKAFETDPARIAGYGTAVGYPPLREWIAAKHNVPVEQVIVTNGSLQADAFLFDALVTPDSPVIVERPTYDRTLLGLRNRRGQLHPVHVQPDGLDVAELAEILKGGVRPTLAHVIPNFQNPAGVTLSGPKRTELLRLANEYDFVIFEDDPYLDIRFRGENLPTMLELDDNDKVVFASSFSKTICPGLRTGYLVGPTDLIKKITTMATNTYVAPNMLAQATVYQFAASGALDASIANVKKALAERADALGAALTKHLPQATFVLPDGGYFLWVDFGDDVDVDKLAPAAEARGVQVVKGTGFVVDGGQHSLRLAYSAVSTDRIDEGVRRLAAAVEDCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q387</accession>
    <name>D3Q387_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015628.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0339"/>
    <dbReference type="EnsemblBacteria" id="ADD40057">
        <property type="protein sequence ID" value="ADD40057"/>
        <property type="gene ID" value="Snas_0339"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0339"/>
    <dbReference type="HOGENOM" id="CLU_541741_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="472" mass="52577" checksum="1B86C275D147D02B" modified="2010-04-20" version="1">MDPITIAIIGLIAARVVGLGATDIAYAVRGKDSPRWEARKAAIKASAQTGRPVRYGFGGYMADMIDDAWISARERRERKHTGPAPHKNKPMRSYLGRVWGHRWEDAGLKHDKKHRDRQIKRGLVDPDTPVEGSVDDAFATVPRDQAANHFNTEGDPRASAGDPFTPDDLRRYGEWVKQRLAPRHHAAVDEWVTAESQAARDRSSFFDHRFTELADVDNSLNSWLNGTHPVVVQRQRSQDLIDQAMDLVDTTAKEPTQEEPIANSDTAMDHGDVDDLRTNPNPDPDGADMFKHPLDQRPDAFMAWVRQTYPDSWQQRLELTPELTKSEWDHHILDKEATTTDTPSAESSTPMEPTTPSTVTYLHEFINRKDPNTMTTTANAEAVGLDDAITYAEQSTQHHTDTASALELFKISLAQGGCGQGTLGIVDEIDDANTVIQGLYQRLHDSLVQDKVTVGDAYNARPDAGTKEFVTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3S6</accession>
    <name>D3Q3S6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6286 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019564.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4346"/>
    <dbReference type="EnsemblBacteria" id="ADD43993">
        <property type="protein sequence ID" value="ADD43993"/>
        <property type="gene ID" value="Snas_4346"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4346"/>
    <dbReference type="eggNOG" id="ENOG5033MQF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128210_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046253">
        <property type="entry name" value="DUF6286"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19803">
        <property type="entry name" value="DUF6286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6286" evidence="2">
        <location>
            <begin position="67"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="169" mass="18641" checksum="B5AA12B63C04807A" modified="2010-04-20" version="1">MRILNRLAAILLAVALVAGGALLVAETVLVWLARPPLLVPRDAWYRALTQTSAGDSIVLVVSASVLALGVIVLFLQLRPWRPVRLPANKPDWFLRRRSAQHSLAAAVDRLPSVAQARARLGRGWRLRLRASGDAQDRDAVREAAVAELERLAAADTSRLRVRLTRRRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Z6</accession>
    <name>D3Q3Z6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021452.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6261"/>
    <dbReference type="EnsemblBacteria" id="ADD45881">
        <property type="protein sequence ID" value="ADD45881"/>
        <property type="gene ID" value="Snas_6261"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6261"/>
    <dbReference type="eggNOG" id="ENOG50331AT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051256_2_2_11"/>
    <dbReference type="OMA" id="TIRQPWA"/>
    <dbReference type="OrthoDB" id="2016960at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="160" mass="17654" checksum="ECFE3B06C3382DDB" modified="2010-04-20" version="1">MTAQPCLRAITVRQPWAELITYARKTVENRSWTCTWRGLLAIHAGKTPEADAAEICRYFGLRKPSALTYGAIIAVARLVDVHDNCSGDCSYWAEPEAQFHWVLADTVDLRQPMNCSGKQRLWTPEADTATAVLDQLPARLHAAPGIDASTDPSPLEVIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q438</accession>
    <name>D3Q438_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase PA-phosphatase related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6304</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021494.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6304"/>
    <dbReference type="EnsemblBacteria" id="ADD45923">
        <property type="protein sequence ID" value="ADD45923"/>
        <property type="gene ID" value="Snas_6304"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6304"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078789_0_0_11"/>
    <dbReference type="OMA" id="RVADWAF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="96"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="256" mass="27857" checksum="0CAFDA8F5AE8E971" modified="2010-04-20" version="1">MSEWRVYGGAPRRWWPDLALLLGFVGLTALLLWPSPLVSLDVAVRDAGQAALSPVPYWIARGLTYLGQGLPLSIGCGIIAVLVARRHRSWRPVLLFASVYVGLAVVLGLKQWFDRIPPRWPDPGNPPYVDAVGAVLFGGDGGVSYPSGHLANTAVWYGLAIALVGERLSRRNRLLLLTAPPLIVLVAQTYLGFHWLSDQPAGYVLGLLIVRGARRVFTYVEVRRRRRVSRARRNRLTNAGSAASAAGLSSSSDNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4I6</accession>
    <name>D3Q4I6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0430"/>
    <dbReference type="ESTHER" id="stanl-d3q4i6">
        <property type="family name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40146">
        <property type="protein sequence ID" value="ADD40146"/>
        <property type="gene ID" value="Snas_0430"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0430"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_13_3_11"/>
    <dbReference type="OMA" id="HIPTENA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="50"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="296" mass="31971" checksum="DE10F7D115811585" modified="2010-04-20" version="1">MSFRTPGKTVVPEYARPMSEFSETEVWRAEVLVDGEPASYLTAGQDGPVVLLLHGTYWSRVWLPVIGELARAGLRPVAVDFPGLGRSGGELTLETATVPALADWVVRFASALRISGPLAVAGHDIGGAVAQHLLVHDLLDVSRLALVNSVAYDSWPAPHVARYRDPDTVAATTAAELLSARRRAVASALSGAATEGLIAEYLEPWTEARVQRSWLAMAGAADSRHTLDLVPALRRSTVPKLLIWGEDDDFEKVAYAEMFASEMPRTTLMRIPDADHIPTENAPVPIARALGDFFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4J2</accession>
    <name>D3Q4J2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0437"/>
    <dbReference type="EnsemblBacteria" id="ADD40152">
        <property type="protein sequence ID" value="ADD40152"/>
        <property type="gene ID" value="Snas_0437"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0437"/>
    <dbReference type="eggNOG" id="ENOG50333G0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133099_0_0_11"/>
    <dbReference type="OMA" id="ANGAFWI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045590">
        <property type="entry name" value="DUF6463"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20064">
        <property type="entry name" value="DUF6463"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="14911" checksum="E607420C8493D6AE" modified="2010-04-20" version="1">MTKVDKTPGSALNRWAGYLMVFIALAHTAFFVPAAEWSQWLSGGLWNGAASDASYATFWALPGGFVPALLVLGLLVVRQARRGEYLPAYVGWVLLAWCVGCTALIGPSGFISGIAPAVLLIGGNLAARRAATSHSHRAGVAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4T1</accession>
    <name>D3Q4T1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zf-CGNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2428"/>
    <dbReference type="EnsemblBacteria" id="ADD42111">
        <property type="protein sequence ID" value="ADD42111"/>
        <property type="gene ID" value="Snas_2428"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2428"/>
    <dbReference type="eggNOG" id="COG5516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087298_0_0_11"/>
    <dbReference type="OMA" id="CGARAKM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010852">
        <property type="entry name" value="ABATE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023286">
        <property type="entry name" value="ABATE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021005">
        <property type="entry name" value="Znf_CGNR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35525">
        <property type="entry name" value="PTHR35525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07336">
        <property type="entry name" value="ABATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11706">
        <property type="entry name" value="zf-CGNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160904">
        <property type="entry name" value="SSF160904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-CGNR" evidence="1">
        <location>
            <begin position="128"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="20495" checksum="89755628AEE034B0" modified="2010-04-20" version="1">MEDMVEPSAATAFIRDFANTVDVEDRTDKLATRAGLDTWLRDNGLPTGEASEPILTLRAGLRERLLLNNNGDADTDLIAAAEHVLRGVPLYARLGTDPVPDDPLLAETALARVARDWAVTVASGEWIRLKQCPDHACLWVFWDGSRSRTRRWCTMRVCGNRAKTRAYTARHREPAQADLSLAKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5D8</accession>
    <name>D3Q5D8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021569.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6382"/>
    <dbReference type="EnsemblBacteria" id="ADD45998">
        <property type="protein sequence ID" value="ADD45998"/>
        <property type="gene ID" value="Snas_6382"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6382"/>
    <dbReference type="HOGENOM" id="CLU_1833983_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="140" mass="14321" checksum="056B15C94BAFDBA4" modified="2010-04-20" version="1">MTTETPAAVGKPPKAATLLLAGTCVAYLLLTGLDAKSTAVLAGSLDFFGLKTVALDGLLALGFGYVALRLRRGGQGVHVVAFVLTGAALWRAIDVLLDAASASLGNDFQYWRIGQLATAALLVIAGVAAVVASALLARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5E1</accession>
    <name>D3Q5E1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell envelope-related transcriptional attenuator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6385</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021572.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6385"/>
    <dbReference type="EnsemblBacteria" id="ADD46001">
        <property type="protein sequence ID" value="ADD46001"/>
        <property type="gene ID" value="Snas_6385"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6385"/>
    <dbReference type="eggNOG" id="COG1316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016455_0_2_11"/>
    <dbReference type="OMA" id="YDRQTHQ"/>
    <dbReference type="OrthoDB" id="491753at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048243" evidence="3">
        <location>
            <begin position="19"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="4">
        <location>
            <begin position="87"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD46001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="358" mass="38716" checksum="D1FA3BDB303E9AD7" modified="2010-04-20" version="1">MGRRGRRRAVSPRSPVWAKVLVGTGAVLMTASMVTVGYTKMMLDKVNDSVHSKDLLGNSGGGGDIKGPLNFLMIGTDQRVGSKAEARTDSIMVLHVNSSLTEATIVSIPRDLRVEIANCGTLFSSPCQTKINDAYPAGGPSVEGSVSNLAETVTHLTGVSFDGAAIVNFEGFLDVVKTLGSVELCLPMEMTPAHAKGQTFPKGCNDYGYADALGIVRERYAYDPTNPEFDPSWGIGDYGRQHMQQHFVKQLLKRAAEKGYLSDPTKVGDLIARIGDQLTLDLGGHTPVDFAFALRGIKPEALATVKIPSEPADIEGVSYVVTQPGEQQETADRLYEAIRSDDLDKWIPENNEWVNKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5G3</accession>
    <name>D3Q5G3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit PurS</fullName>
            <shortName evidence="5">FGAM synthase</shortName>
            <ecNumber evidence="5">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Formylglycinamide ribonucleotide amidotransferase subunit III</fullName>
            <shortName evidence="5">FGAR amidotransferase III</shortName>
            <shortName evidence="5">FGAR-AT III</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit III</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purS</name>
        <name evidence="6" type="ordered locus">Snas_6407</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PurS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021594.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6407"/>
    <dbReference type="EnsemblBacteria" id="ADD46023">
        <property type="protein sequence ID" value="ADD46023"/>
        <property type="gene ID" value="Snas_6407"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6407"/>
    <dbReference type="eggNOG" id="COG1828">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_164833_1_0_11"/>
    <dbReference type="OMA" id="IENYRFE"/>
    <dbReference type="OrthoDB" id="2012814at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01926">
        <property type="entry name" value="PurS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003850">
        <property type="entry name" value="PurS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34696">
        <property type="entry name" value="PTHR34696"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02700">
        <property type="entry name" value="PurS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="SSF82697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00302">
        <property type="entry name" value="TIGR00302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD46023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="91" mass="9778" checksum="241535DEFF2FEF05" modified="2010-04-20" version="1">MARVVVDVMLKPEILDPQGEAVVNALPRLGVAGVSGVRIGKRIELEFSDDLDEATVLERANEAADKLLANPVIETYTLRVETPHAVNAESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5M4</accession>
    <name>D3Q5M4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6469</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021655.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6469"/>
    <dbReference type="EnsemblBacteria" id="ADD46084">
        <property type="protein sequence ID" value="ADD46084"/>
        <property type="gene ID" value="Snas_6469"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6469"/>
    <dbReference type="eggNOG" id="COG0124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058236_0_0_11"/>
    <dbReference type="OMA" id="ICACRDR"/>
    <dbReference type="OrthoDB" id="1317397at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD46084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="273" mass="28725" checksum="49DBDDD87D770F1D" modified="2010-04-20" version="1">MCSHQLNAIPSLLRGLIDDAAVFPPGNAPLPEALASHREHRNAWYAGLVGPLLLPSSKLADVPESDEPLRVGLIADTGIEAVSQVLAQLPPGVEITHVEARADDDEAMEALVAASTRWGLRVFAEIPMTADVSHALKTLGPTSITPKFRTGGETADKFPSPQTLATAIVGCAEQGLSFKLTAGLHRAVRHTDPETGFVHHGFANVLLAATDADGGAGVASVTDTLSITESGPLRDRIRGMLAHPRPLWVGFGSCSIVEPLEDLSGLSLVYEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5T1</accession>
    <name>D3Q5T1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0515</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015801.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0515"/>
    <dbReference type="EnsemblBacteria" id="ADD40230">
        <property type="protein sequence ID" value="ADD40230"/>
        <property type="gene ID" value="Snas_0515"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0515"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058221_0_0_11"/>
    <dbReference type="OMA" id="VGYIGYM"/>
    <dbReference type="OrthoDB" id="1345431at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010645">
        <property type="entry name" value="MFS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06779">
        <property type="entry name" value="MFS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="18"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="399" mass="41549" checksum="22DC20E4F4C7E16C" modified="2010-04-20" version="1">MTVSIERPTTVRGPAAWQVGLAGTAMIAATFGFARYSYGLYAPALRAEFDLSVGLVGLIGSATYVGYLLSLLVVGVFSQRLGPRPLVVIGGLSAAVGMLAVGLATGPWLLVAGLVLAGTSPGWAWAPYSDAVDRLVEPGKRQRVMGLIPSGTAFGVVLAGPAALFLYGPVWRVAWLVFAVITFAVTVYNALILPGTRRRETPDVETQARVGPSWFLRPGVTRHYLTAFSYGLIGAIYWTFAVEAIAADSTRSTAPLFWTLMGAVGMLGALAGVAIGRYGLRVVHIGLFASMAAAILLLGLAPGSLAAVIASAVLYGPAFMAGSSLLQVWSYELFPDRPTTGFSATVFFIGIGTILGPTLAGQIASGWGLGITFVATATVAAATLAIAPRRQAAIRTPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5T4</accession>
    <name>D3Q5T4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DEAD/DEAH box helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0518</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0518"/>
    <dbReference type="EnsemblBacteria" id="ADD40233">
        <property type="protein sequence ID" value="ADD40233"/>
        <property type="gene ID" value="Snas_0518"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0518"/>
    <dbReference type="eggNOG" id="COG1205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000809_3_2_11"/>
    <dbReference type="OMA" id="CIQSPKC"/>
    <dbReference type="OrthoDB" id="35275at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022307">
        <property type="entry name" value="Helicase_put_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018973">
        <property type="entry name" value="MZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09369">
        <property type="entry name" value="DUF1998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03817">
        <property type="entry name" value="DECH_helic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="65"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="280"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="763" mass="82514" checksum="25A2AF5616CAAE62" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q630</accession>
    <name>D3Q630_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphopantetheine-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2524</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017776.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2524"/>
    <dbReference type="EnsemblBacteria" id="ADD42205">
        <property type="protein sequence ID" value="ADD42205"/>
        <property type="gene ID" value="Snas_2524"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2524"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2669286_0_0_11"/>
    <dbReference type="OrthoDB" id="1943389at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="75" mass="8006" checksum="96E7AB7EE1049FBB" modified="2010-04-20" version="1">MSKPIEDKLLSIMADKFDIEPGKITPTTSFEAMDVDSLVLVELSVLAEKQFGVRLGDAGTIRGAALLLRDNGVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q640</accession>
    <name>D3Q640_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-diphosphocytidyl-2C-methyl-D-erythritol synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017786.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2534"/>
    <dbReference type="EnsemblBacteria" id="ADD42215">
        <property type="protein sequence ID" value="ADD42215"/>
        <property type="gene ID" value="Snas_2534"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2534"/>
    <dbReference type="eggNOG" id="COG2068">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061980_2_2_11"/>
    <dbReference type="OMA" id="LFGAAHW"/>
    <dbReference type="OrthoDB" id="1432587at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="1">
        <location>
            <begin position="5"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="193" mass="20646" checksum="1878DDF661DEF32B" modified="2010-04-20" version="1">MSVAGLVLAAGAGTRFGRPKALVEYRGATLLDRAVTILREGGCETVYGVLGISAYAARARSATAFTPVYNPRWHTGMGSSLRAGLAALDREHEGVVVLLVDQPGISPVSVRRVREAHALGALVAMAVYNGRRGHPVCFDRGLWPEIAEAAHDDVGAREFLRAHPDLITEVACDGLGDPRDIDTPADLARLRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q641</accession>
    <name>D3Q641_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, PucR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CdaR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2535"/>
    <dbReference type="EnsemblBacteria" id="ADD42216">
        <property type="protein sequence ID" value="ADD42216"/>
        <property type="gene ID" value="Snas_2535"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2535"/>
    <dbReference type="eggNOG" id="COG2508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017436_4_2_11"/>
    <dbReference type="OMA" id="DCDGSWT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041522">
        <property type="entry name" value="CdaR_GGDEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012914">
        <property type="entry name" value="PucR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17853">
        <property type="entry name" value="GGDEF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07905">
        <property type="entry name" value="PucR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PucR" evidence="2">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF_2" evidence="4">
        <location>
            <begin position="277"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_30" evidence="3">
        <location>
            <begin position="446"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="505" mass="54354" checksum="EC9E01C226A8A7A5" modified="2010-04-20" version="1">MDLHALLQMPELGLTLLSGQGHLDRKIRWVVPTDLPDPRRYLSGGELVLTGMLWRHDETDADKFVGCIAAAGVSALGAGDPERSDIPAELVDACRRHDLPLFHVSPEVSFSTITERVVQRLSAHRSADVAAVLGRHRQLIASGGGLGEVLALVHDELGMDCQILSATGRVIRSSTPEATPSASARRTIAAKVLGGGPLPRRIRVNKRSEYSVFGVGGPSPHCGWMLVVDDDHTQWPPQRRDVTEELVALISLELRRTVERDQSEHDLVLALDTGADHLASHLAHAGLSGPGGYVVAVCTATGPASLSLGPSVLTEAIAPASAAFTLARRHGEVIAVARVESGHAEIVAHAREVAATLSKGLRDDRVAIGISDAVDSAEALTGALSEARHAVHLATAREAAVEVAGPDDLTSHVLLMATVPDGVRRAYRSKVLGPVLEYDKEHKSELVSTLEEFLECEGSWSRCAAKLHLHVNTLRYRIERVERLTGRDLRRLTDRVDLFLALRVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q682</accession>
    <name>D3Q682_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc finger SWIM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2577</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017828.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2577"/>
    <dbReference type="EnsemblBacteria" id="ADD42257">
        <property type="protein sequence ID" value="ADD42257"/>
        <property type="gene ID" value="Snas_2577"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2577"/>
    <dbReference type="eggNOG" id="COG2345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023622_1_0_11"/>
    <dbReference type="OMA" id="HRELPYD"/>
    <dbReference type="OrthoDB" id="448815at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="407"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="451" mass="48581" checksum="F3142770AE8AC147" modified="2010-04-20" version="1">MTTTPQVYRYLRPSTIASGRLGLATSGGVTTQGAAANPDFFTGFLQHPETAATGLLATAAVARARYFQPGLASLRDPVVTCDGDGLRFESFSSCGGVYARFDVASAALDGEMRDRGTTNVDFNAALCEALAKVGGRDPLRLNVGAEELSVTTTDTKVTEKKVPLPQRWLRGFAEVQVITPRFDLRAELSAPEATRFLRSLPTGEQAADIVWLSVAGRGLRRTSRPAPGAVCLAGPSRLETLRPLLRFAKSLRVYGPPVTHSAPPTASAWELVLPDMRLMLTLSPEPRRGFSGEGAVLDALIDDAVESDAELIGNLLDFRPYIDIAVLADTSGLSPQRVRAALTQLGTAGRVGYDVANASFFHRELPYDADKVEQLNPRLRNARALARSGAVHITGDIANVTSRDKRYQVRLDADGLPAGCTCRWWAEHRGERGKCKHVLAVHMSLNGSDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q689</accession>
    <name>D3Q689_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2584</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017835.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2584"/>
    <dbReference type="EnsemblBacteria" id="ADD42264">
        <property type="protein sequence ID" value="ADD42264"/>
        <property type="gene ID" value="Snas_2584"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2584"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_61_1_11"/>
    <dbReference type="OMA" id="LLMTGHF"/>
    <dbReference type="OrthoDB" id="1384345at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="21"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="402" mass="40432" checksum="C2393484798304EC" modified="2010-04-20" version="1">MTTTLTPAPTRPRRSAALGWIGVVAVATGTFSIVTTEMLPVGLLTRIGPDLGVSDGASGQLMTTASSMAFVAALTIVLVAGRLDRRFVLAGMMGVLLVANLVTALTDSFVVLLAARVMVGMAIGGFWAIGASLATRLVPERSVARASSVIFSGVSIASVAGVPAGMFIGDHAGWRAAFLALAGLSAIVLVAMLTLLPALPSRRSLRPRDLAVLLRNRPVLIGLGGLALIVIGHFTAYTYVTPALKAAAGIDGGAAAVVLLIYGSAGIAGTFVAGALTGGHLRAVLLTSGGFIVAATVAIPLLVSGPITATVTLIVWGLGYGAVPVGLQVLTLRSAPEAPEAVSALFVAGFQVAIGLGAVFGGVAVDLSGPQAPMWVGAIAAAAMVALVFAAVRLPHRPRDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6D4</accession>
    <name>D3Q6D4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017880.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2631"/>
    <dbReference type="EnsemblBacteria" id="ADD42309">
        <property type="protein sequence ID" value="ADD42309"/>
        <property type="gene ID" value="Snas_2631"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2631"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_88_16_11"/>
    <dbReference type="OMA" id="RAWRMLY"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="178"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="282" mass="30993" checksum="BB6172F7AB79B156" modified="2010-04-20" version="1">MSTGKNSVRYWRDGVRPLEAMQANFHDHVYCPHSHDAYSFGITDAGAQRFRCRGAQHVSAAGMVMSFNPDEAHDGRAAAELGYHYRIVHIGQSVVRDILADASDGRSPALPLFASPVLTDRTLTEALGRLHSALLGSASDLVREELLTTAVLTMAEHGATRAPRLRTLAGTQQRAAARRARAVLDEAPLEPVSARQLAEAAGYSRFAVYRAFRAEYGMAPSDYQRLVRLRRARRLLTDGVPPGRAAASSGFADQAHFNRWFKRAYGLTPAIYQRSAGHRNHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6G8</accession>
    <name>D3Q6G8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4567</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019782.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4567"/>
    <dbReference type="EnsemblBacteria" id="ADD44211">
        <property type="protein sequence ID" value="ADD44211"/>
        <property type="gene ID" value="Snas_4567"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4567"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="DAYVHTM"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="21"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="103"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="172" mass="19752" checksum="10AA3BF9268625DC" modified="2010-04-20" version="1">MRVRHDAEFQEYARSKLDSMRYFAYLSCGDWHRAEDAVQVAFVKLYAAWGRAARESLDAYTRRIVVNVLINEGRRFRFRREHLDDDPAVPVTWDGDDRSDDRMVLLQALSGLPRRQRITLVLRFWEDLSVEQTAAIMRCSPSTVKSQSVKGLAAMRDRLSGSFPTLPKGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q712</accession>
    <name>D3Q712_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015982.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0698"/>
    <dbReference type="EnsemblBacteria" id="ADD40411">
        <property type="protein sequence ID" value="ADD40411"/>
        <property type="gene ID" value="Snas_0698"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0698"/>
    <dbReference type="eggNOG" id="COG3599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1824142_0_0_11"/>
    <dbReference type="OrthoDB" id="2060110at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019933">
        <property type="entry name" value="DivIVA_domain"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03544">
        <property type="entry name" value="DivI1A_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048917" evidence="2">
        <location>
            <begin position="35"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="141" mass="15017" checksum="8A13B03C6CE734B4" modified="2010-04-20" version="1">MEFVLVVLALALSCGIAFGIVVLVTGNDPGLVSATDGVPAHLPSDRPLSEQDVLAAKFDTGLRGYQTGQVDDALARLAYDVGFKDELIKVLASEVTALRDGRTEEADALRDARQRALADKEDLTGDAGETTDETEPKEDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q715</accession>
    <name>D3Q715_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015985.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0701"/>
    <dbReference type="EnsemblBacteria" id="ADD40414">
        <property type="protein sequence ID" value="ADD40414"/>
        <property type="gene ID" value="Snas_0701"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0701"/>
    <dbReference type="HOGENOM" id="CLU_1034090_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="269" mass="29169" checksum="C026E8B2AE8E2CC1" modified="2010-04-20" version="1">MSQHGPHGGYPDQGPSGYPQYSPSYYSQPVTGAQPVTGMPMMGAAPQQPQPDPRPRGPLKFLVPLCVVLALAFGGSAYFFFISGDAPSEVVGQYITHAQDEDFAGAREFTSDSATKATKFQGNSEGMETMRRWFGEDTMRWEVRGDSTSGSKSTVTVDKTLVLPNYDEPVEMRWDYRLERESGNWKIDRVKIMSIVDDGIAGPGDCMLATGFAYEAADCSDGPNSEASVLVEVTDAVDVPDDCPNPTGPAVETTKKRILCIEEQSPESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q779</accession>
    <name>D3Q779_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2673</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017921.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2673"/>
    <dbReference type="EnsemblBacteria" id="ADD42350">
        <property type="protein sequence ID" value="ADD42350"/>
        <property type="gene ID" value="Snas_2673"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2673"/>
    <dbReference type="eggNOG" id="COG2311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036065_1_0_11"/>
    <dbReference type="OMA" id="SAWWSDT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012429">
        <property type="entry name" value="HGSNAT_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04235">
        <property type="entry name" value="DUF418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07786">
        <property type="entry name" value="HGSNAT_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="HGSNAT_cat" evidence="4">
        <location>
            <begin position="36"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="DUF418" evidence="3">
        <location>
            <begin position="321"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="434" mass="45807" checksum="1A25BA3477F4FC5B" modified="2010-04-20" version="1">MTDTDTVRSERTLRPFRTDRETPPQPKPQRGGALGRVLGLDLARALAIFGMFYAHVGPMQEFKNPVVNTIMQIPHGRASALFAVLAGLSLVLLAGGRRPLPALERRQRIVKIVIRALLLIALGTALTLWLHTDIVILAFYGLFFLLALPFVRCGVKTLAVLSAAFAVVGSVVFYWIAMAQPSFVTALNAHDPITRMGADGLGRLLFTGLYPAVPWLAYIFAGMAIAKLDLSAKRVRIGMASVGAGLGLAGYGLSWVLQKVLFAGGGMGGGSGSSGSSTASTSTASGSSGMSGSSGTWSDSMSGFDPWSSDMLQFLLSASPHSGTAFELLGNIGIAMLVITGSVVLLDRSALAQKLLAPVTAAGAMSLTLYVAHLWALNHVPSNSDGGSVTAALAVWGWFCVAGIAFAFVWSRFFKRGPLEYAMQWATSPAKLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q864</accession>
    <name>D3Q864_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018009.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2762"/>
    <dbReference type="EnsemblBacteria" id="ADD42438">
        <property type="protein sequence ID" value="ADD42438"/>
        <property type="gene ID" value="Snas_2762"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2762"/>
    <dbReference type="eggNOG" id="COG1376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_516690_0_0_11"/>
    <dbReference type="OMA" id="GHVYTSW"/>
    <dbReference type="OrthoDB" id="376756at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="484"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="527" mass="57155" checksum="B72E99534AFB8C41" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q869</accession>
    <name>D3Q869_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TAP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018014.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2767"/>
    <dbReference type="EnsemblBacteria" id="ADD42443">
        <property type="protein sequence ID" value="ADD42443"/>
        <property type="gene ID" value="Snas_2767"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2767"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_3_1_11"/>
    <dbReference type="OMA" id="LNCAYWP"/>
    <dbReference type="OrthoDB" id="665798at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048937" evidence="1">
        <location>
            <begin position="27"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="104"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="546" mass="58366" checksum="06B2ABC0FA1F9C7B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8A1</accession>
    <name>D3Q8A1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNA polymerase, sigma 28 subunit, Sig B/F/G subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_2799</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018046.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2799"/>
    <dbReference type="EnsemblBacteria" id="ADD42475">
        <property type="protein sequence ID" value="ADD42475"/>
        <property type="gene ID" value="Snas_2799"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2799"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_8_5_11"/>
    <dbReference type="OMA" id="CGVNTAK"/>
    <dbReference type="OrthoDB" id="1857862at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014322">
        <property type="entry name" value="RNA_pol_sigma-B/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02980">
        <property type="entry name" value="SigBFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="7">
        <location>
            <begin position="50"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r3" evidence="6">
        <location>
            <begin position="132"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="8">
        <location>
            <begin position="214"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="267" mass="30423" checksum="0E25E2AC69A8272C" modified="2010-04-20" version="1">MRNATLSRTRTQPTPARREDLDPQVKPVLERMERLKKTDPRRRALRNTVVQRALPLADRLARRFEHRGQPLEDLTQVARLGLINAVDNFKCGRGGGFTHFAVPSILGELKRHFRDKGWLVRVPRRLQETRLAFNEASKDLSQRLGRSPTLEDYAEYLSMPVEQVRAGINCVGAYEGVSLHTPAHRESSEELIDSLGGSDPAMASAEARMLLRPAIKELTPRECRILSLRFVDDLHQSEIAREVGLSQMHVSRLLRQTLTKLRERLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8K3</accession>
    <name>D3Q8K3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4804</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4804"/>
    <dbReference type="EnsemblBacteria" id="ADD44445">
        <property type="protein sequence ID" value="ADD44445"/>
        <property type="gene ID" value="Snas_4804"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4804"/>
    <dbReference type="HOGENOM" id="CLU_1958243_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="128" mass="13888" checksum="0B5FB646FB9E0636" modified="2010-04-20" version="1">MDHVVPQGDRRSRFEARLRDVETELARLRGVRDTMVAAGARARELAATLAADTVASTSDDGVATVSCDGRGHVDTVVFDRAGYNRIDEKQLCDSVLQARYRARDRARRESAAVGRDLFHGDSGAATGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8N0</accession>
    <name>D3Q8N0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4831</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020043.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4831"/>
    <dbReference type="EnsemblBacteria" id="ADD44472">
        <property type="protein sequence ID" value="ADD44472"/>
        <property type="gene ID" value="Snas_4831"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4831"/>
    <dbReference type="eggNOG" id="COG1141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_6_0_11"/>
    <dbReference type="OMA" id="CVMVASE"/>
    <dbReference type="OrthoDB" id="1873445at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001080">
        <property type="entry name" value="3Fe4S_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00352">
        <property type="entry name" value="3FE4SFRDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 4" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="65" mass="6862" checksum="2D832B343329BC05" modified="2010-04-20" version="1">MRLSADRDTCVGAGMCVLTAPEVFDQDDEQGRVVILDPGVVDERAEAVREAAVLCPAAALTVTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8S1</accession>
    <name>D3Q8S1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4872"/>
    <dbReference type="EnsemblBacteria" id="ADD44513">
        <property type="protein sequence ID" value="ADD44513"/>
        <property type="gene ID" value="Snas_4872"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4872"/>
    <dbReference type="HOGENOM" id="CLU_1785713_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="145" mass="14921" checksum="EFD30053A61E1A5F" modified="2010-04-20" version="1">MALWMVVAVAAIAGGVAAILFTGAGTTSTQILSPAQVRDALEDADTTTSGEPEEPEPSGESEPQTKTTAAGTVTVTCRGDAIASDTVTPAADWDADDPAGNDVKREVTFTTDQPTAHEASQDGGDTLVVAYTCRSGEVAWDSRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8U0</accession>
    <name>D3Q8U0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020103.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4891"/>
    <dbReference type="EnsemblBacteria" id="ADD44532">
        <property type="protein sequence ID" value="ADD44532"/>
        <property type="gene ID" value="Snas_4891"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4891"/>
    <dbReference type="HOGENOM" id="CLU_1958244_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="128" mass="13333" checksum="9B8492DF033261F3" modified="2010-04-20" version="1">MTDEPYIDFDGDGSEDEYSTEELDGGGYAHTSEDGEVAYDYDGDGLIDELHTDEDGNGSLDTVHIDETGDGYMDSEESLEEEPADTEEPPADTTAGSSSGMPLGYLGGEGTASGTEEETGATEKPAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q973</accession>
    <name>D3Q973_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell division FtsK/SpoIIIE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0972</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016253.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0972"/>
    <dbReference type="EnsemblBacteria" id="ADD40682">
        <property type="protein sequence ID" value="ADD40682"/>
        <property type="gene ID" value="Snas_0972"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0972"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020567_1_0_11"/>
    <dbReference type="OMA" id="CLKVMGQ"/>
    <dbReference type="OrthoDB" id="374938at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="3">
        <location>
            <begin position="348"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="364"/>
            <end position="371"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="719" mass="77918" checksum="85611FFFB3931C28" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Q6</accession>
    <name>D3Q9Q6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44602">
        <property type="protein sequence ID" value="ADD44602"/>
        <property type="gene ID" value="Snas_4963"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4963"/>
    <dbReference type="eggNOG" id="ENOG50346NH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109391_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048978" evidence="1">
        <location>
            <begin position="24"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="150" mass="15820" checksum="CE1F35A5F934F90E" modified="2010-04-20" version="1">MRFTVKKVLSAAVLVAVTGGALAFSGASAVAQQDGTSRINDSFETVTTDRGGVVVFEDYGPGAPGGGGNDDYVQIGDEGDDGYGVRAYAWVNGNYKGVKYFGKGYLEYTIWDPFGNVKAGQRVKIKVCLARWSGAPNENCGSKTRTITDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9T1</accession>
    <name>D3Q9T1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020198.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4990"/>
    <dbReference type="EnsemblBacteria" id="ADD44627">
        <property type="protein sequence ID" value="ADD44627"/>
        <property type="gene ID" value="Snas_4990"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4990"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027938_4_1_11"/>
    <dbReference type="OMA" id="QYNTGRV"/>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="57"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="257" mass="28595" checksum="2BE316822E68EBBC" modified="2010-04-20" version="1">MPRSKDKLDAKYWFGRPGGDRRGFWLLVVAQPIKWFLWFIASRTWSGMRHVPMKGGVILACNHISQADPLVVAHFVYNTGRNPSFLAKDGVFKVPVVGKLIKWTGQIPVYRGGTDAVKSLHAAIERVDSGGSVIFYPEGTTSKQPEHWPMRGRTGVARLAMETGAPVIPMTVWGPQRIFDPIRKKARFRLRAPVTVTAGPPVDLSAWEGAEPNAENLNAMTDAIMLRIRDQLAELRGEAAPPLYDLKAAKKKSREET</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9X9</accession>
    <name>D3Q9X9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016262.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0981"/>
    <dbReference type="EnsemblBacteria" id="ADD40691">
        <property type="protein sequence ID" value="ADD40691"/>
        <property type="gene ID" value="Snas_0981"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0981"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_709616_0_0_11"/>
    <dbReference type="OMA" id="GWIANHT"/>
    <dbReference type="OrthoDB" id="2213221at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="389" mass="38987" checksum="4B7E5E35E429D8EA" modified="2010-04-20" version="1">MVDYAQLRNLDTSKLTSAAEAAGGLSSAVTSRGGEVANAAQIPQGMWAGLDSSAASGMMSPLSNPLYDVSDSATHSQGVITTLVDDLEKAKSKLDDAHDVIAGTGITISPDGTVTTPVVNDPAVAAENDRKAKEAKRIIDEAVADANGADDKASGALASVGQFLAQTLGPPQNSPLGPWATASWGAGQAAGRFGNLASWMGTAHYGRFAPYAKLPNGMHSFLSPSNMSAWQRAKAGADGQFRAIPYKSGTRAAWANAGKWVGRGGGVLSGITGGATQLSKDWSDPNMGTDEKVGRAAWRGGLEGGGAYGGGILGAKVGAGIGTLIAPGVGTVVGGAIGGLVGGIAGSKAGGWIANHTVDFAGDAVDSIGNGLSAAKDKAGEVWEDITPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAH7</accession>
    <name>D3QAH7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Activator of Hsp90 ATPase 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018331.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3089"/>
    <dbReference type="EnsemblBacteria" id="ADD42760">
        <property type="protein sequence ID" value="ADD42760"/>
        <property type="gene ID" value="Snas_3089"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3089"/>
    <dbReference type="eggNOG" id="COG3832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108923_4_0_11"/>
    <dbReference type="OrthoDB" id="1498264at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="161" mass="18305" checksum="4B49FF0AFCF76278" modified="2010-04-20" version="1">MNGASYVYVSLIEATPRQVWRALTDPGYIALYFDNAGPRSNWRVGSTVEWCTEEGEPYHDWGQRVLESTPERRLSYTWHNYEPEMAKYFPEWTGDRLAELRREPVSTVTFDLEPVGDAATKLTMVHDGFAEGSQMLAGVSEGWPQILSKLKTVLEADSPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAZ9</accession>
    <name>D3QAZ9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020366.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5160"/>
    <dbReference type="EnsemblBacteria" id="ADD44795">
        <property type="protein sequence ID" value="ADD44795"/>
        <property type="gene ID" value="Snas_5160"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5160"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116681_1_1_11"/>
    <dbReference type="OMA" id="GWHVLET"/>
    <dbReference type="OrthoDB" id="1832160at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="130" mass="13687" checksum="6CEB179A62154BCF" modified="2010-04-20" version="1">MTHGVDGDVLLLDLPAAPAFLPVLRTATAGLATRLSFGLDAIEDLRLAVDEAAGLMMAAVDNHDASAILNCRFDVTETELLISIGAAGIGSLPPRQSFDWRVLDALTGSVSTELHNGVTTVRLAQPRPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB16</accession>
    <name>D3QB16_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1123"/>
    <dbReference type="EnsemblBacteria" id="ADD40833">
        <property type="protein sequence ID" value="ADD40833"/>
        <property type="gene ID" value="Snas_1123"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1123"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_339760_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="189"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="535"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="625"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="701"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="815"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="230"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="579"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="626"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="641"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="725"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="750"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="836" mass="91334" checksum="187FB4165EE8841D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBD3</accession>
    <name>D3QBD3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3144</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018386.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3144"/>
    <dbReference type="EnsemblBacteria" id="ADD42815">
        <property type="protein sequence ID" value="ADD42815"/>
        <property type="gene ID" value="Snas_3144"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3144"/>
    <dbReference type="eggNOG" id="COG2807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038046_1_0_11"/>
    <dbReference type="OMA" id="RDPLAWQ"/>
    <dbReference type="OrthoDB" id="806182at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="8"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="411" mass="42527" checksum="CD66AF355DE5D1FC" modified="2010-04-20" version="1">MSASTSARTWLIATGVILAALNLRTAVTSVGPLLDLIQHDLGMSASVAGVLTTLPVLAFAVLGGLTPLLSRRFGPQSVLIAALAVMAAGLIVRAMVPSTTVFLVASAAALAGGAVGNVAIPGMVKLYFPDRIGAMTTVYTTSLALGTTVAAAIAVPLADGFGGHWQPALGLWAVPAVLAMVPWLLLRSPKATAEAPRPVQQPLPGLTRSRIAWLMLLAFGSQSLIAYSMFGWLPEMMRDHGYDASTAGFMLAIFNAVSVPISMVVPVIAGRLNSQRPVLAVLLAGYLLGFPGLWLGGVSAWTWISLLLVAVGMGTFPLMLTMFALRTRTAGGTAGLSAFAQSGGYLLSGLGPLLIGVLLEATGSWTAPFALLLTAVAVHAFAGWRIARPRFLEDELAAPEPTVARPVPANC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBZ4</accession>
    <name>D3QBZ4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020454.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5249"/>
    <dbReference type="EnsemblBacteria" id="ADD44883">
        <property type="protein sequence ID" value="ADD44883"/>
        <property type="gene ID" value="Snas_5249"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5249"/>
    <dbReference type="eggNOG" id="ENOG5030S65">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130344_0_0_11"/>
    <dbReference type="OMA" id="ITIFHMI"/>
    <dbReference type="OrthoDB" id="2004651at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020348">
        <property type="entry name" value="Uncharacterised_YvaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17314">
        <property type="entry name" value="DUF5360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="15879" checksum="954849F36D9FC5AA" modified="2010-04-20" version="1">MERPPAWIKRSMLATDLGFVAYWTATAIAAIPPYPRQILIDWNWSYLVLDLLASLSGLAALLALRRGVAHARTLMVVSLALTHAAGLTALNFWVLRGEFDLMWWIPNLWLALFPIAAIGRLMRSPRRGAVTSARACRTLPGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC28</accession>
    <name>D3QC28_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Anaerobic ribonucleoside-triphosphate reductase-activating protein</fullName>
            <ecNumber evidence="7">1.97.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_5283</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the organic radical-activating enzymes family.</text>
    </comment>
    <dbReference type="EC" id="1.97.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020488.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5283"/>
    <dbReference type="EnsemblBacteria" id="ADD44917">
        <property type="protein sequence ID" value="ADD44917"/>
        <property type="gene ID" value="Snas_5283"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5283"/>
    <dbReference type="eggNOG" id="COG0602">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089926_1_0_11"/>
    <dbReference type="OMA" id="EVNGPGC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043365">
        <property type="term" value="F:[formate-C-acetyltransferase]-activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012837">
        <property type="entry name" value="NrdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352:SF2">
        <property type="entry name" value="PTHR30352:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000368">
        <property type="entry name" value="NrdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="25"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="184" mass="19730" checksum="A4DD5FF9ECFDB710" modified="2010-04-20" version="1">MTSTVRVHATLSDSRANGPGERFVVWFQGCSLACPGCFNPETHGPDAEELSVAELAGRVLARADRWEGITLTGGEPLQQPEAVAELCRRIREGSRLGVLILTGYTRGEIEADPARLAAVADADLVIAGRYNAGLRLGTGLRGSSNKTYWWLTDRYREADLAAVPEAEVRIGADGTLIFTGMEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU66</accession>
    <name>D3PU66_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpmE</name>
        <name evidence="8" type="ordered locus">Snas_1303</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds the 23S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016583.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1303"/>
    <dbReference type="EnsemblBacteria" id="ADD41012">
        <property type="protein sequence ID" value="ADD41012"/>
        <property type="gene ID" value="Snas_1303"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1303"/>
    <dbReference type="eggNOG" id="COG0254">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114306_4_0_11"/>
    <dbReference type="OMA" id="WYPDAKV"/>
    <dbReference type="OrthoDB" id="2014569at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00501">
        <property type="entry name" value="Ribosomal_L31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_L31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027491">
        <property type="entry name" value="Ribosomal_L31_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_L31_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="PTHR33280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01143">
        <property type="entry name" value="RIBOSOMAL_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="75" mass="8278" checksum="3A1392985920FC74" modified="2010-04-20" version="1">MKPDIHPAYVTTEVTCSCGNTFTTRSTVEGGKIHAETCNVCHPFYTGKQRILDSGGRVARFQKKYAKAQAAKKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUH3</accession>
    <name>D3PUH3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Creatininase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3320</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the creatininase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018557.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3320"/>
    <dbReference type="EnsemblBacteria" id="ADD42986">
        <property type="protein sequence ID" value="ADD42986"/>
        <property type="gene ID" value="Snas_3320"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3320"/>
    <dbReference type="eggNOG" id="COG1402">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055029_0_0_11"/>
    <dbReference type="OMA" id="PCFLWSG"/>
    <dbReference type="OrthoDB" id="984747at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024087">
        <property type="entry name" value="Creatininase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003785">
        <property type="entry name" value="Creatininase/forma_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35005">
        <property type="entry name" value="PTHR35005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02633">
        <property type="entry name" value="Creatininase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102215">
        <property type="entry name" value="SSF102215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="26760" checksum="1CF60A85FA3388B9" modified="2010-04-20" version="1">MPPDFLRLAAIDRGQVARIAPEAVLVLPIGAIEQHGPSLPLGTDAALAEAVAEAGIEASATSRPLVLAPTIPYGNSIHHLFACAGSVSSRTLQLVLADLIDSFVRSGFRRIFILNGHGGNDECVHLAVKDAVNRHPVVLGAASYWTLVPDGIFPADQVPGHAGAFEASLLMAARADLLPPDAAAGGPPGSSMVHTGDFGPGVTVVRAGDWATSGGFTDDPAKADIEAGRECLRALGQRLGQALDRFADVSLPDDDQAGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUV7</accession>
    <name>D3PUV7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase M28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5347</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020552.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5347"/>
    <dbReference type="EnsemblBacteria" id="ADD44981">
        <property type="protein sequence ID" value="ADD44981"/>
        <property type="gene ID" value="Snas_5347"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5347"/>
    <dbReference type="eggNOG" id="COG2234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019249_1_0_11"/>
    <dbReference type="OMA" id="FAFIDDH"/>
    <dbReference type="OrthoDB" id="1255662at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049259" evidence="3">
        <location>
            <begin position="35"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="317"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="362"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="485"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="518"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="552"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M28" evidence="4">
        <location>
            <begin position="111"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="743"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="743"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="772" mass="81204" checksum="3EEDC129BB74AEFE" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUZ2</accession>
    <name>D3PUZ2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020587.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5384"/>
    <dbReference type="EnsemblBacteria" id="ADD45016">
        <property type="protein sequence ID" value="ADD45016"/>
        <property type="gene ID" value="Snas_5384"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5384"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_2_0_11"/>
    <dbReference type="OMA" id="ELSNICC"/>
    <dbReference type="OrthoDB" id="1748559at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="149" mass="16098" checksum="67BCBA2D78D49F26" modified="2010-04-20" version="1">MTTELRPGALAEAAGINRETLRYYERRGLIAEPHRTIGGHRLYPPETVTVLKVIKAAQRLGFTLNEIEDLLAVGAHRHGRRRNDAGLQARAAAKLAEVEQKIADLTVIGDTLRQAIAAGCDDLVACSANQCCPIPFADIVTDDPGSHHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV38</accession>
    <name>D3PV38_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1384</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016662.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1384"/>
    <dbReference type="EnsemblBacteria" id="ADD41091">
        <property type="protein sequence ID" value="ADD41091"/>
        <property type="gene ID" value="Snas_1384"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1384"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="RNIWLAQ"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="14"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="294" mass="30617" checksum="A2C716653B60DC6D" modified="2010-04-20" version="1">MSGTVTPADKALGITCRGLVYIYHLDGYDVVALSGVDIDIAAGESVALVGPSGSGKSTLVALTAGLLRPAAGRLHVGGHDLVKADDDELQRLRAGEIGMILQGSDRNLIPYLSAVDNIRFAQRGIRRRDRADLASPRELLALVGIDSEADANARISQLTLGQRQRLAVAVGIAGGAGLLLADEPTAQLDAEARDEVVQALLAVHAAGHTVVVVTHDPEVGAHMGRTVTIRGGRVGSEGRRGEDFLVMGAGGTVHLPPEVTARFPAGSLLRVAQDEDGVVRLWAADSGLETKDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV44</accession>
    <name>D3PV44_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016668.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1390"/>
    <dbReference type="EnsemblBacteria" id="ADD41097">
        <property type="protein sequence ID" value="ADD41097"/>
        <property type="gene ID" value="Snas_1390"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1390"/>
    <dbReference type="HOGENOM" id="CLU_148707_0_0_11"/>
    <dbReference type="OrthoDB" id="1893188at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="135" mass="14623" checksum="8382CFBC43DE604C" modified="2010-04-20" version="1">MGDNQVTGGDIHKLWMTAHMDISAVEDAYIKLTEQLDGDVAEGDEGKYGKAFDSWNIYREIVQLALFRTAVSARATRLALDLAVSEFTFVDGDAANGITDAGKEFLEAVGDENQTPPEYVVEPEGDPVAPLGNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVG1</accession>
    <name>D3PVG1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018646.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3411"/>
    <dbReference type="EnsemblBacteria" id="ADD43075">
        <property type="protein sequence ID" value="ADD43075"/>
        <property type="gene ID" value="Snas_3411"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3411"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_1_5_11"/>
    <dbReference type="OMA" id="RWHEEQP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041467">
        <property type="entry name" value="Sco4008_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17926">
        <property type="entry name" value="TetR_C_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="22458" checksum="F297C939D257EDC4" modified="2010-04-20" version="1">MATSDTGDKRNATQTRQRILDAALDEFSAKGYSGARTAGIAKRAGVNVQLISYYFGGKEGLLDALRETWRERRSSLEDSSAESSFLDGFRAALDVTLRDPRRARLVVWQALGDYPGDTGPLVAEWERVAASAVEQTRARQSEGQIGSETSPEFVALLQFLLAFAPVAIPQAVQGIYGVDPLSAEYRERVSRQLARLLGADDDGETT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVY6</accession>
    <name>D3PVY6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable nicotinate-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Deamido-NAD(+) diphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Deamido-NAD(+) pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nicotinate mononucleotide adenylyltransferase</fullName>
            <shortName evidence="6">NaMN adenylyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nadD</name>
        <name evidence="8" type="ordered locus">Snas_5476</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NadD family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.18" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5476"/>
    <dbReference type="EnsemblBacteria" id="ADD45107">
        <property type="protein sequence ID" value="ADD45107"/>
        <property type="gene ID" value="Snas_5476"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5476"/>
    <dbReference type="eggNOG" id="COG1057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069765_1_1_11"/>
    <dbReference type="OMA" id="IHIGHLI"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02165">
        <property type="entry name" value="NMNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00244">
        <property type="entry name" value="NaMN_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00482">
        <property type="entry name" value="TIGR00482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="13"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="207" mass="22798" checksum="DF14F014A3C5FC0E" modified="2010-04-20" version="1">MGDKGSRPRRVGVMGGTFDPIHNGHLVAAAEVADRCDLDEVVFVPTGQPWHKADTTVSDAEHRYAMTLLATASHPRFRVSRVDVDRPGPTYSVDTLRDLGRKYGPGVRLFFIIGADTVETVLTWKAVDEVFSLATFAAVNRTGHRRGATRLPAHAEVVTVDMPGIDVSSTDCRERVAQGRPIWFLTPDEVVRYIDKHGLYRATVGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW05</accession>
    <name>D3PW05_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020697.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5495"/>
    <dbReference type="EnsemblBacteria" id="ADD45126">
        <property type="protein sequence ID" value="ADD45126"/>
        <property type="gene ID" value="Snas_5495"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5495"/>
    <dbReference type="HOGENOM" id="CLU_518657_0_0_11"/>
    <dbReference type="OMA" id="DHHGEPD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038332">
        <property type="entry name" value="PPE_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="538" mass="55949" checksum="E2BBFB3FFF5F1A30" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW97</accession>
    <name>D3PW97_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016825.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1551"/>
    <dbReference type="EnsemblBacteria" id="ADD41254">
        <property type="protein sequence ID" value="ADD41254"/>
        <property type="gene ID" value="Snas_1551"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1551"/>
    <dbReference type="HOGENOM" id="CLU_2572179_0_0_11"/>
    <dbReference type="OrthoDB" id="2229490at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="81" mass="8165" checksum="3AFBC0C2449B5607" modified="2010-04-20" version="1">MSAFLSHASRVCIVLLLVGGVVVTFGQVVGIAIADAELVTVLGTTGVSAISVIAGLAAIFAFVRSYGRQGKADQAKAVTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWA6</accession>
    <name>D3PWA6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016834.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1560"/>
    <dbReference type="EnsemblBacteria" id="ADD41263">
        <property type="protein sequence ID" value="ADD41263"/>
        <property type="gene ID" value="Snas_1560"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1560"/>
    <dbReference type="eggNOG" id="COG2764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_17_2_11"/>
    <dbReference type="OMA" id="LEKQMWG"/>
    <dbReference type="OrthoDB" id="2051456at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06588">
        <property type="entry name" value="PhnB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028973">
        <property type="entry name" value="PhnB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06983">
        <property type="entry name" value="3-dmu-9_3-mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-dmu-9_3-mt" evidence="1">
        <location>
            <begin position="7"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="138" mass="14895" checksum="B4E3E9D90282CCBD" modified="2010-04-20" version="1">MTSLLNPYISFDGDAADAMKFYQSVFGGDLAVNTFGETGYDDPAFADKVMHAKLETGNGFHLMAADTPPGGEHKPGNNISISLSGDDGDTLRGYWNKLSESGTVMMPLEKQVWGDEFGMCADRFGIAWMVNISQPQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWB6</accession>
    <name>D3PWB6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cobalamin (Vitamin B12) biosynthesis CbiM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1570</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016844.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1570"/>
    <dbReference type="EnsemblBacteria" id="ADD41273">
        <property type="protein sequence ID" value="ADD41273"/>
        <property type="gene ID" value="Snas_1570"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1570"/>
    <dbReference type="eggNOG" id="COG0310">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137910_0_1_11"/>
    <dbReference type="OMA" id="GDCIAQH"/>
    <dbReference type="OrthoDB" id="2022748at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025937">
        <property type="entry name" value="PDGLE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13190">
        <property type="entry name" value="PDGLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049505" evidence="6">
        <location>
            <begin position="30"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="PDGLE" evidence="7">
        <location>
            <begin position="15"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="117" mass="11806" checksum="8E161F99FBC2EAE3" modified="2010-04-20" version="1">MRVKTGGFILAGLLLALLLAGVVSNFASGSPDGLDSATLEGCTTNAEGEITGGECMAQKAADHDLSGGPFADYATAGIGNDFLSTAISGVLGVIVVFAIGAGIFWLVKRRDLATDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWM3</accession>
    <name>D3PWM3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43245">
        <property type="protein sequence ID" value="ADD43245"/>
        <property type="gene ID" value="Snas_3584"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3584"/>
    <dbReference type="HOGENOM" id="CLU_1309482_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="210" mass="22156" checksum="42CF48B4E45795C7" modified="2010-04-20" version="1">MRPPGVTPPVAPGRNIGLIVGLVIAGVAVLLAGVGVAVAVWPQEADSAALVAAGRDNVYGTTSTPCDLVDQQELADLVGFEGAKYDEETYGPDDDFDYNGMLCQLSTQVSDVTEYPLFELRAESHADTASADSAFEERVAEIGIEESVGLEQTMLLLKPNGSSPACLIMRNGNLVLTMELDSNYLDIPEDAAGDFLTDSAKKVMAALKDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWP7</accession>
    <name>D3PWP7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage/plasmid-related protein TIGR03299</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3609</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018840.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43269">
        <property type="protein sequence ID" value="ADD43269"/>
        <property type="gene ID" value="Snas_3609"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3609"/>
    <dbReference type="eggNOG" id="ENOG502Z7QU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058825_0_0_11"/>
    <dbReference type="OrthoDB" id="1540547at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026325">
        <property type="entry name" value="DUF932"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017686">
        <property type="entry name" value="Phg/plasmid-like_prot"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06067">
        <property type="entry name" value="DUF932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03299">
        <property type="entry name" value="LGT_TIGR03299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="395" mass="44052" checksum="420FB83D488C170F" modified="2010-04-20" version="1">MDAAFDVNDAFAQAKLDQIRAADNQQAAIAAQVARGDLQPLGGDTYRVMTGWDRGEIIAYDTVQGIIAHHGLDTTTGQAALYSAAPPWHGLGCYIPGGTRDIDEVLKLSRLDFTVHTTPALYQWDDQLHTHPDKFHTLRSDTAAPLGVVGSKYHTVQNRECFEFLRNLVESYDVVWESAGAVRGGRRTFVSMRLPDTVTVDAAGINDTITPFVVVFNSHDGSSSITAVVTPYRPVCANTERLALDNAYTSWSIRHTESAMHQMRQARRTLKMSVKYYDEFAAQQTTLAHHDMVIDEFRALIDELWPLEPNATKRGKTNAKNRREALMAQWDTESRRCGSTLYAAERAITGYIDHDKPRMLGKFSTLNAARATAIVEGRDDGLKTKAHKKLMLRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWQ2</accession>
    <name>D3PWQ2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3614</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018845.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3614"/>
    <dbReference type="EnsemblBacteria" id="ADD43274">
        <property type="protein sequence ID" value="ADD43274"/>
        <property type="gene ID" value="Snas_3614"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3614"/>
    <dbReference type="HOGENOM" id="CLU_1004393_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="277" mass="30688" checksum="3313E68231FD9F01" modified="2010-04-20" version="1">MFRINIPIPPPNESNALLARSAAAATHTFNHPDADPQSERTHPAGYLATALMHLSDQLVDDSAGFANEALPATTLDCVDEFNKAKNQRCPHCHSPYIESRAWHEPCPTCGQPAHSAEPRTTTLSLTTHLTPPKHTHSIANRNQAEQAANALNAFMVEQSNGHMSPDIQSLLRHDQEVLTIIVASAFKGIIHLTRSHDLSPAVVMAAAIARYAQDINNETQELRDTPRMRGCLHCEQIVTDQFRWHEKCQSCRDAHKDVISILRCLTCDNPDECTGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX48</accession>
    <name>D3PX48_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5642</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020843.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5642"/>
    <dbReference type="EnsemblBacteria" id="ADD45272">
        <property type="protein sequence ID" value="ADD45272"/>
        <property type="gene ID" value="Snas_5642"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5642"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="AQQCHRI"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="230" mass="24282" checksum="081196071EA3F8BE" modified="2010-04-20" version="1">MSTPVIELRGTTRRYDEGPPALDDVSLTVGAGEAVAILGPSGSGKSTMLNLIAGLDRPSQGTVTVDGTRVDGLSEAASARYRRAKVGMVFQFFNLLDDLTVADNVTLPALLAGMRRREARSRAAELLDSLGIKRLAAAHPARLSGGERQRVAVARALMNRPTLLLADEPTGALDSASGLEVRQLLNELHADGQTIVLVTHDLALAEACATRTVRLVDGHVAADTAMEPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXE9</accession>
    <name>D3PXE9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1713</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016983.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1713"/>
    <dbReference type="EnsemblBacteria" id="ADD41412">
        <property type="protein sequence ID" value="ADD41412"/>
        <property type="gene ID" value="Snas_1713"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1713"/>
    <dbReference type="eggNOG" id="ENOG5030QJH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112770_0_0_11"/>
    <dbReference type="OrthoDB" id="1973662at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="208" mass="22966" checksum="764B7B31B37F478C" modified="2010-04-20" version="1">MNSLIRELTDVLCPGMSIPAEFQHLYDWITANGNTSLHNGRTSGWLAMPGEQAATTGIEFRADGTELLEHWLGTEDRAVIQRLCVFAITGAEGSMAAFWLDDDGGQRIVHMGSGSGSTTVCLLGREPLDFLRLLAIGYDELCWSEDWDEPPSDEDGHPVSADSSYRRWLVTEYGVTVPRTGLDIATPTEMDDEDPADPFARWLTTIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXJ9</accession>
    <name>D3PXJ9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018900.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43329">
        <property type="protein sequence ID" value="ADD43329"/>
        <property type="gene ID" value="Snas_3672"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3672"/>
    <dbReference type="eggNOG" id="ENOG503431C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129331_0_0_11"/>
    <dbReference type="OMA" id="CEIAKPA"/>
    <dbReference type="OrthoDB" id="246606at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048676" evidence="2">
        <location>
            <begin position="29"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="167" mass="17669" checksum="5068D006424A9555" modified="2010-04-20" version="1">MRFPVLRAVAIMLVAALALSACKDNASKDDAKPRDEASSSKSSPSSSPSAADTEVPKTSGAAVDRYEDYLHAVGKSELDTMCEIAKPAMDTVPGDCESNFKIMLGMFSADQLKALETATIDTSQVKKQGPGTVDIPASAVQADATFGANDLGDVTLEYQKDNWFIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXU1</accession>
    <name>D3PXU1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dephospho-CoA kinase</fullName>
            <ecNumber evidence="3">2.7.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Dephosphocoenzyme A kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">coaE</name>
        <name evidence="4" type="ordered locus">Snas_3764</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>3'-dephospho-CoA + ATP = ADP + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18245"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CoaE family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the UPF0157 (GrpB) family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the CoaE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.24" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018992.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3764"/>
    <dbReference type="EnsemblBacteria" id="ADD43421">
        <property type="protein sequence ID" value="ADD43421"/>
        <property type="gene ID" value="Snas_3764"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3764"/>
    <dbReference type="eggNOG" id="COG0237">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2320">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067032_0_0_11"/>
    <dbReference type="OMA" id="IRVDGWP"/>
    <dbReference type="OrthoDB" id="1515383at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007344">
        <property type="entry name" value="GrpB/CoaE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04229">
        <property type="entry name" value="GrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00152">
        <property type="entry name" value="TIGR00152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="395" mass="43047" checksum="DD727E95E9A13D55" modified="2010-04-20" version="1">MLSVGLTGGIGAGKSTVARRLTELGAVLIDSDVLAREVIAPGTPGLAKVADTFGADILDATGALDRAALAQRVFADPEARTRLEAIIHPLVRQRSVELAEAAADDAIVVNDVPLLAEVGLAPTFDLVIVVEASHELRLERLTARGLPAEQAQARIAAQASDDVRRAVADVVIDNAGTVDDLNAAVDALWHERLVPFEDNKRNRRIARRSETITMADYSPQWPSRFERLAARLRHVMGDKALRVDHVGSTAVPGLVAKDVIDIQITVADLADADAAAEQLAAAGFPRLEGITNDTPKPFAPEVSQWRKRMHCGCDPRNITQIHIRQVDSAGWRYALLFVDWLRADTAARDDYAHHKRALANDHATTSDYADAKEPWFDLALPRAEDWAKRTNWHPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY89</accession>
    <name>D3PY89_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Proline--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="8">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">proS</name>
        <name evidence="10" type="ordered locus">Snas_1758</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017027.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1758"/>
    <dbReference type="EnsemblBacteria" id="ADD41456">
        <property type="protein sequence ID" value="ADD41456"/>
        <property type="gene ID" value="Snas_1758"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1758"/>
    <dbReference type="eggNOG" id="COG0442">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016739_0_0_11"/>
    <dbReference type="OMA" id="NCDYAAN"/>
    <dbReference type="OrthoDB" id="665824at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00861">
        <property type="entry name" value="ProRS_anticodon_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01569">
        <property type="entry name" value="Pro_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004500">
        <property type="entry name" value="Pro-tRNA-synth_IIa_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023717">
        <property type="entry name" value="Pro-tRNA-Synthase_IIa_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044140">
        <property type="entry name" value="ProRS_anticodon_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00409">
        <property type="entry name" value="proS_fam_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="38"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD41456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="562" mass="61344" checksum="21F5E639C651FC19" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYA0</accession>
    <name>D3PYA0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide TPR_4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1770"/>
    <dbReference type="EnsemblBacteria" id="ADD41467">
        <property type="protein sequence ID" value="ADD41467"/>
        <property type="gene ID" value="Snas_1770"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1770"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_1_11"/>
    <dbReference type="OMA" id="NEFESAW"/>
    <dbReference type="OrthoDB" id="490981at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="81"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="741" mass="80788" checksum="3D67AD74FDE51976" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYD0</accession>
    <name>D3PYD0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_1801</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017068.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1801"/>
    <dbReference type="EnsemblBacteria" id="ADD41497">
        <property type="protein sequence ID" value="ADD41497"/>
        <property type="gene ID" value="Snas_1801"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1801"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_3_1_11"/>
    <dbReference type="OMA" id="WISPIWH"/>
    <dbReference type="OrthoDB" id="1891092at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="9">
        <location>
            <begin position="12"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD41497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="253" mass="27756" checksum="578CDB9CFFB2D243" modified="2010-04-20" version="1">MIGTLHALEYWWMNYRRVWYGSVFSSFVMPVLFLVSIGYGVGSYVGSTESLGGVDYAAFVAPGLLASTALQMVGGEMTWPVFAALRWGQQYKAMQTSPLTPRQILSGHLLYGLIRVAVTAIVFAVVMAAFGIFSATAPLSVVATIGVGYAFIGWVYAFSVSVKSETTLSIIHRFGIVPVSLFSGVFFPLSQLPAYLQPLAWISPLWHGAELSRWAVSGTPTPWPWYLHIAYLLVLGTVGWWLAGAQLRRRMTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYD8</accession>
    <name>D3PYD8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017076.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41505">
        <property type="protein sequence ID" value="ADD41505"/>
        <property type="gene ID" value="Snas_1809"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1809"/>
    <dbReference type="eggNOG" id="ENOG503419Q">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1123968_0_0_11"/>
    <dbReference type="OrthoDB" id="2151172at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="247" mass="27655" checksum="E265E07693A62C8A" modified="2010-04-20" version="1">MPNLPSNDELDALVEELFSTLGNERTGDDFHFDPESLSESTRFYYVDFLKWLGIDDSVLEAERICIHAGREQPANLDRRRINESGVDGYSLFIDNSLYRSLDAVYAALAHQFTHLRLIIDEDQTLAEAQKCRPIELDTKGKKDDDDDDDDDDEKDTKPAVNADLEIRTEVASFVLGFGKLVLNGAAEWDELDIDDDEGFEDITTLPLSSLAYLYKKVANHADVGTKAMEAGLTDEAKEALGKVKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYE2</accession>
    <name>D3PYE2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017080.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1813"/>
    <dbReference type="EnsemblBacteria" id="ADD41509">
        <property type="protein sequence ID" value="ADD41509"/>
        <property type="gene ID" value="Snas_1813"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1813"/>
    <dbReference type="eggNOG" id="COG1808">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075569_0_0_11"/>
    <dbReference type="OMA" id="MAVGPEF"/>
    <dbReference type="OrthoDB" id="1006184at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005240">
        <property type="entry name" value="DUF389"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20992">
        <property type="entry name" value="PTHR20992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04087">
        <property type="entry name" value="DUF389"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="312" mass="32944" checksum="1E421B09CEDD83D4" modified="2010-04-20" version="1">MQHLRIISPVDRTDAVCEALSGHCGVTNLVVFPNSARKPAGDLVQCDVARESVNEVLDELDALGIDDDGSIAMERVDLSISLAADNAKDAAPGDGEDAVVWDELAQKVDESSRLTWSFVAFLAIATQIAAIGVLLDSPIMIVGAMVLGPEFGPVAAIGFGMLRREWWRIGVSVRTLVFGFAAAIAVTWLCAFVSVHLGWIEPVMLDTGSETKFIVKPDKWSFIVAVLAGIAGVLSLTSDKSSALVGVFISVTTVPAAGYIAVAIALAHWAEVTPSIIQLGLNLGGMIVSGLATLIVLRLLWGRAGLRERIGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYI3</accession>
    <name>D3PYI3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1854</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017121.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1854"/>
    <dbReference type="EnsemblBacteria" id="ADD41550">
        <property type="protein sequence ID" value="ADD41550"/>
        <property type="gene ID" value="Snas_1854"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1854"/>
    <dbReference type="eggNOG" id="COG0631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067299_0_0_11"/>
    <dbReference type="OMA" id="PWFTARL"/>
    <dbReference type="OrthoDB" id="1359757at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="247" mass="26115" checksum="6A139A8B09984B15" modified="2010-04-20" version="1">MEIAAATLASPGSPNDDTYIAGQGFAAVLDGATAPKDRDSGCVHDVPWLVARLSGHLAALLTHEDQTPLPRLLAATIERTRADHGDTCDLSNPDSPSSTVTVLREGPNTVDYLVLGDSPLVLRGPGDTVQAIVDDRVEHLPSYTYEAVARLRNSPEGFWVASTDVGAAGHALTGSLPRGEVTRALLLTDGASRLADRYGRDWPDLLVTAEKSGPQTLLNEVRAADATAPASRGKRFDDATAVWCRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYI8</accession>
    <name>D3PYI8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1859</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017126.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1859"/>
    <dbReference type="EnsemblBacteria" id="ADD41555">
        <property type="protein sequence ID" value="ADD41555"/>
        <property type="gene ID" value="Snas_1859"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1859"/>
    <dbReference type="eggNOG" id="ENOG5033JPI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108513_0_0_11"/>
    <dbReference type="OMA" id="MRVYVPL"/>
    <dbReference type="OrthoDB" id="1943830at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="163" mass="17486" checksum="7002E4A954BC4D4B" modified="2010-04-20" version="1">MTRIYLPATIAVLRELRDAGKYRAERAHAVTPGLREWYTEGDLEDLEYVAFTRAAQDSLWLLRADTAAPRRRAVVSADVADTEVSTTGGELGASDVSLLAPVSLSAVAAIHVDGAEAETDVTVAVGALSAASDGDADLQFIVESVEDHELEWYDPTELDQLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ10</accession>
    <name>D3PZ10_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5809"/>
    <dbReference type="EnsemblBacteria" id="ADD45439">
        <property type="protein sequence ID" value="ADD45439"/>
        <property type="gene ID" value="Snas_5809"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5809"/>
    <dbReference type="eggNOG" id="ENOG5031XHA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094927_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048474" evidence="1">
        <location>
            <begin position="22"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="232" mass="25048" checksum="BB17132903ADFC65" modified="2010-04-20" version="1">MRIRAIAAMGLAAAALLTVSACRVEQGAALFVGDERISEKRVDEVVDSISASDRAKLADLNQLTGGQLPDISTGNLRGYVVDALVVTELGQRVAADTGVKPDRESSSVIKKNWELLELDSDSEFVQLTAEAEAYRTVLVDGSKPHRPSDKEVDALTAQLEHTFGQELDEQQKAGFAQFLTSEDGQVVVGQQRQVSDYIAEYDVTANPRYGQSFIVIARNAGPQPLITSDIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZI5</accession>
    <name>D3PZI5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1963</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017230.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1963"/>
    <dbReference type="EnsemblBacteria" id="ADD41659">
        <property type="protein sequence ID" value="ADD41659"/>
        <property type="gene ID" value="Snas_1963"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1963"/>
    <dbReference type="eggNOG" id="ENOG502ZD5A">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074786_0_0_11"/>
    <dbReference type="OMA" id="DAFANWY"/>
    <dbReference type="OrthoDB" id="1378624at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021247">
        <property type="entry name" value="DUF2785"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10978">
        <property type="entry name" value="DUF2785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="264" mass="29375" checksum="959044BBD8B0B089" modified="2010-04-20" version="1">MTDWQRVKDADFAVPDDKPLADLVAELTGNLRSPDPVLRDEQSYYVLATWVEKGVLDGDLERLGDEMAALLDDPEVQARTFATLILGEIVDRGTYFPRWLDAFANWYPSEVDLRGHDEKLGWLHAVAHGADTLKAFGGHTDVDPARMLSIAAQRLLAPTEFVWRDQEDDRLAFAVAHVLTRPELTEADSVGWLAAVDTDFTSGEPGPPPPHASNTMRTLRLLYILADRGVRPSWRGGDVTQLQHRDAVKQRLAEVLARVAPFTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZQ3</accession>
    <name>D3PZQ3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3937</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019161.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3937"/>
    <dbReference type="EnsemblBacteria" id="ADD43590">
        <property type="protein sequence ID" value="ADD43590"/>
        <property type="gene ID" value="Snas_3937"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3937"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1446826_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="187" mass="20858" checksum="AC774CB0803FDEF4" modified="2010-04-20" version="1">MPKPTASTDRRQQLVEAAFDEIAANGFEGLRTRAVARAVGIDHSTVHHHFATKADLIAAVVDHAIAPFRTGKPLTGSPAEQLRDHLNLLVRLMRERPRLFIVLRELDLRATRDDNIRAILAERDNRWRDTTTTLFRQPGWHSDTDPEAAAELVIAAVKGASFAPDPDRAAAAIDELLRLLTPREERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZX6</accession>
    <name>D3PZX6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase</fullName>
            <ecNumber evidence="10">2.4.1.227</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">murG</name>
        <name evidence="13" type="ordered locus">Snas_4011</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1-&gt;4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:31227"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="ChEBI" id="CHEBI:61388"/>
            <dbReference type="EC" id="2.4.1.227"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 28 family. MurG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.227" evidence="10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019234.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4011"/>
    <dbReference type="CAZy" id="GT28">
        <property type="family name" value="Glycosyltransferase Family 28"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43663">
        <property type="protein sequence ID" value="ADD43663"/>
        <property type="gene ID" value="Snas_4011"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4011"/>
    <dbReference type="eggNOG" id="COG0707">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037404_1_0_11"/>
    <dbReference type="OMA" id="AADMMLC"/>
    <dbReference type="OrthoDB" id="1165736at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051991">
        <property type="term" value="F:UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050511">
        <property type="term" value="F:undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00033">
        <property type="entry name" value="MurG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006009">
        <property type="entry name" value="GlcNAc_MurG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 10" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9 10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 10 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="11">
        <location>
            <begin position="7"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="12">
        <location>
            <begin position="197"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-N-acetyl-alpha-D-glucosamine binding" evidence="10">
        <location>
            <begin position="14"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD43663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="372" mass="39635" checksum="668EFEC60DACE4F1" modified="2010-04-20" version="1">MTQLRSVVLAGGGTGGHVYPLLAFADCLRRHEPDVRITCLGTEKGLEKDLVPAAGYDLRMVPAHQLPRKVNLDLIKTGPRMMRATKVTRGIMDEVDAQAVVGFGGYVSVPAYLGAWRRKTPMVIFEFNDPIGVANRLGMRFDHKLAVGFPHLPQQVPGLKDGTVTGVPLRTGISQLDRAARKAEARAKLGLDPDRTTLFVFGASQGANSINQAVAGAAASLTGSGAQVLHVIGARRDEPVEVPANLPAKYITMPFLNEMELGYAAADLVLCRGGAMTCAEVAAVGLPAVYVPLPWGNREQYKNAGPVVAAGGGLFCDDADISPQWIERELIPLLRDPARLTDMGAAALAFGRRDGDEALRRLTIEAVAEAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q071</accession>
    <name>D3Q071_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5974</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5974"/>
    <dbReference type="EnsemblBacteria" id="ADD45600">
        <property type="protein sequence ID" value="ADD45600"/>
        <property type="gene ID" value="Snas_5974"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5974"/>
    <dbReference type="HOGENOM" id="CLU_3398642_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="31" mass="3327" checksum="4406C9DBA2B8BB2E" modified="2010-04-20" version="1">MLNRTSSVWLKGVAIPSGPIDMTGTNPLEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0I1</accession>
    <name>D3Q0I1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2022</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017288.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2022"/>
    <dbReference type="EnsemblBacteria" id="ADD41717">
        <property type="protein sequence ID" value="ADD41717"/>
        <property type="gene ID" value="Snas_2022"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2022"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_22_0_11"/>
    <dbReference type="OMA" id="CYRMTGV"/>
    <dbReference type="OrthoDB" id="1335404at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014303">
        <property type="entry name" value="RNA_pol_sigma-70_ECF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02957">
        <property type="entry name" value="SigX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="18"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="113"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="301" mass="33037" checksum="9697F3BFFC88443E" modified="2010-04-20" version="1">MTAGSEDARPDAATEAFVRHRNLLFTVAYELLGSAADAEDVLQETWLRWAGVDLAPVRDHRAYLVRIATRQALTRLRTLSRRKELYVGPWLPEPLVTAPDVAEDVELADSVSMAMLLVLETLTPTERAVFVLREVFDLDYDEIAEAVDKTPAAVRQIARRARSHVAARRPRGAVTSAQTKAAADAFQRAIETGDLQSLVDILAPDVVALSDGGGVKRATPRPIVGADKVAHGLATQWRHLNATPSIEPVHVNGHPGLIMRLDGDIENVIAMRVEDGLITGLYFVRNPEKLSRVEHETALTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q143</accession>
    <name>D3Q143_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4142</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019364.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4142"/>
    <dbReference type="EnsemblBacteria" id="ADD43793">
        <property type="protein sequence ID" value="ADD43793"/>
        <property type="gene ID" value="Snas_4142"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4142"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_2_11"/>
    <dbReference type="OMA" id="VHMRESA"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="100"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="311" mass="33532" checksum="465F2EF9A25967F5" modified="2010-04-20" version="1">MSEAAAQQEAQESMALSAPASGMWRDAFRSLRRRPDAVISAVWILVVILMAVAPWIFTSKDYLACDGDNSKIKPQWFGGEFFLGTNNQGCDYFAMTIAGARPSIFLSFMVILITVTVGFILGGLAGYYGGWIDAIVSRVVEVWMVIPFFLGAVLLLTLFQDFKLGGGQILAVIPPTLALAFFGWTTDTRLVRASVLQAKQFDYVQAARSLGASDRRMLFRHILPNAIAPVLSGLPIAVGAYITTEAALSVLGLGVRPPATSWGTLIAEGAPWVQGGYPHLLIIPGTVLLLTILAFALLGDALRDALDPKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q166</accession>
    <name>D3Q166_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021217.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6021"/>
    <dbReference type="EnsemblBacteria" id="ADD45646">
        <property type="protein sequence ID" value="ADD45646"/>
        <property type="gene ID" value="Snas_6021"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6021"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_60_5_11"/>
    <dbReference type="OMA" id="QYQGFFG"/>
    <dbReference type="OrthoDB" id="1452500at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="410" mass="42515" checksum="1F628A10A598727B" modified="2010-04-20" version="1">MPLRVLPPAGAPRTLALAQLANAIGDGVFIVTSALYFSRIVGLPAGQIGLGLTVGWGLGALAGVPLGHLADRRGPRGVAAALAVATAASVAGLLLVRDFVPFLVVVCFYTCSQCGLLAARQALLAGLVDATERTKVRAYLQSTVNAGLAIGAGFGGLALYFDTEAAYLTVLGLDAAGFAVSALVLSRLPKLPPAPPRASGEPMLAVLRDRPYAVLTFLNGVLLLYMPLLSLVVPLWIVAHTAAPRWLVAATLVLNTASVMLFQVRVARGVTGPDSASRYVRLAGLIMAASCAAFALSTLGKSPWLAALVLLVAAGLQVWGEMTQASGMWEISFALAPSDKHGQYQGFFGSSTTMARMLGPVALTMLIVDWGWPGWLVLGGVFVAAGVAVGPVTRWAQRTRPAAEPERALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1D1</accession>
    <name>D3Q1D1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chorismate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6087"/>
    <dbReference type="EnsemblBacteria" id="ADD45711">
        <property type="protein sequence ID" value="ADD45711"/>
        <property type="gene ID" value="Snas_6087"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6087"/>
    <dbReference type="eggNOG" id="COG1605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139648_2_0_11"/>
    <dbReference type="OMA" id="RFSELGQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010958">
        <property type="entry name" value="Chorismate_mutase_highGC-bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01808">
        <property type="entry name" value="CM_M_hiGC-arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="87" mass="9818" checksum="E186AECDC9559CCD" modified="2010-04-20" version="1">MNADTATTEPDLNTLRERINGIDDEIIRLWKERSQVSKEVGRIRMAAGGTRLVLSRERQICERFREALGEDGTQLALLLLRAGRGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q251</accession>
    <name>D3Q251_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2228</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017489.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2228"/>
    <dbReference type="EnsemblBacteria" id="ADD41918">
        <property type="protein sequence ID" value="ADD41918"/>
        <property type="gene ID" value="Snas_2228"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2228"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="KGMQMKA"/>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="287" mass="31223" checksum="D68DD2BAA886A7D4" modified="2010-04-20" version="1">MEEIALEATGLSKHYRRTRALDNCTVRVPVGRVSALVGPNGAGKTTLMSLACGLRTPTAGEVSVLGQRPDNKGMPDGVAFLSQDKPLYRGFNVSEMLHAASKLNSDFDEDRARRLVADADVPLKAKVKTLSGGQRTRVALAIALGRRPRLIILDEPLADLDPLARKQVMQTLMSDVAEFGTTVVMSSHVLADLEEVCDHLVLLASGHVQLCDEVENLLDNHRLAVGPGIEGEPPFPRESIVEASRTRRETTLLLRQSTDDGPPDWDISSPSLEELVLAYMRTKEAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2C8</accession>
    <name>D3Q2C8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional DNA primase/polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019432.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4212"/>
    <dbReference type="EnsemblBacteria" id="ADD43861">
        <property type="protein sequence ID" value="ADD43861"/>
        <property type="gene ID" value="Snas_4212"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4212"/>
    <dbReference type="eggNOG" id="COG5519">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057861_0_0_11"/>
    <dbReference type="OMA" id="WAACRAY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015330">
        <property type="entry name" value="DNA_primase/pol_bifunc_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09250">
        <property type="entry name" value="Prim-Pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00943">
        <property type="entry name" value="Prim-Pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prim-Pol" evidence="1">
        <location>
            <begin position="17"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="304" mass="31149" checksum="0CE0D4C00D404761" modified="2010-04-20" version="1">MDDGSRILATAELTRHALDYAARGWPVFMLGAGKVPLRLCRPCREADGDHDMEACPCLTCHGFYAASTDPERVVAMVTGHPRGVLALRTGASSGVVVVDVDPRNDGTHTFVRLLADGVLPATVTANTGSRGLHLYYAHPGGTVKSGGNRLGPGVDVKADGAYVVLPPSTVNGKAYTWRPGTDPTSLELSPIGHKLAELLAPAEPSAPVFRPAPMVSASASAFAAPSNARGRLAGLVSVVLSAPEGNRNDVLNWAAYKAADVIMTGAAPAEAVVAALADAAAHIGLAPAETRGTIRSGLRAGGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2D4</accession>
    <name>D3Q2D4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019438.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4218"/>
    <dbReference type="EnsemblBacteria" id="ADD43867">
        <property type="protein sequence ID" value="ADD43867"/>
        <property type="gene ID" value="Snas_4218"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4218"/>
    <dbReference type="eggNOG" id="COG0175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070815_0_1_11"/>
    <dbReference type="OMA" id="IPVRMAN"/>
    <dbReference type="OrthoDB" id="674332at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="273" mass="30141" checksum="51DD7FBD137ECB25" modified="2010-04-20" version="1">MSPLRVIAYGGGVQSTALLVLAASRRIDFVTFLFSNVGNDSEHPATLDYVTRVAKPFAERHGLALVELERVRRDGTTETLYRRLTREGSRSLPIPVRMSNGAPGTRSCTADFKIKVLGRWLKANGATKDNPATVGIGISLDEMHRVNRRRALAYENPVYPLLEHSPPLRRADCLRIIAEAGLPVPGKSACYFCPFHTRDAWATMARDEPDLFARACHLETILNHRRATLGRDPVYLTRYARPLGEAITPAQDTLAGLADLDDDATCDNGACWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2H7</accession>
    <name>D3Q2H7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="15">CDP-diacylglycerol/glycerol-3-phosphate3-phosphatidyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Snas_4261</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4261"/>
    <dbReference type="EnsemblBacteria" id="ADD43910">
        <property type="protein sequence ID" value="ADD43910"/>
        <property type="gene ID" value="Snas_4261"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4261"/>
    <dbReference type="eggNOG" id="COG0558">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051314_2_0_11"/>
    <dbReference type="OMA" id="WSMVYYL"/>
    <dbReference type="OrthoDB" id="1702107at2"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000847">
        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00560">
        <property type="entry name" value="pgsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD43910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="22835" checksum="46713B5AF73B2C67" modified="2010-04-20" version="1">MPREAPGASIYNIPNLLTVLRLLLIPAFVLCAIESQFTNPGWRWAAALVFTAAAVTDYVDGWLARRIGQVTAFGKIADPIADKALTGTALVLFSLWDLLPWWVTIVILVRELGITALRFWVIRLGIIAASRGGKIKTVLQIVAIVWYLVPLPELLAMLAPWVMAAATIATVVSGADYIVQVVRLRHQAGRNGDGDTGAAAGAVEPTPQDDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2I3</accession>
    <name>D3Q2I3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019487.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4267"/>
    <dbReference type="EnsemblBacteria" id="ADD43916">
        <property type="protein sequence ID" value="ADD43916"/>
        <property type="gene ID" value="Snas_4267"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4267"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_5_11"/>
    <dbReference type="OMA" id="WDIAPAR"/>
    <dbReference type="OrthoDB" id="1616572at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="9"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="292" mass="31420" checksum="CBE6C21009C66C42" modified="2010-04-20" version="1">MSIVVTTPTGHVGSRVVRLLVQAGVRPRLLLRDPSRLDAETLSLVEAVPGDLTDATYVRESITGADTVLWVDPTPHFGPDPIDTSLRTAEPLIEAARAGDVNRVVLLSSIGAEKRHGVGHIDALGGIEERLDATDIDVLHVRCAYFFTNLLFEVDGLRDGVLSTAFEPDRPMPWADPRDIGEVIAARLLNPAWHGHLTQAVHGPRDLSFRQVAAILTEALGREIRLQPVTDAQVRDALTEAGLPPSAVDAIAGMSAGSADVKPEQPRDVVTTTPGTLEAWAYSVLRPVIDQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2K9</accession>
    <name>D3Q2K9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021331.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6137"/>
    <dbReference type="EnsemblBacteria" id="ADD45760">
        <property type="protein sequence ID" value="ADD45760"/>
        <property type="gene ID" value="Snas_6137"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6137"/>
    <dbReference type="HOGENOM" id="CLU_1061340_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048816" evidence="1">
        <location>
            <begin position="28"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="262" mass="27663" checksum="728A0EAFD792F941" modified="2010-04-20" version="1">MRPLAVVLTLAALVGGLAACGQKDGDAKSPADEGIRKFDFANAEVRLGTGGKYQLKDGDYTEKGYEGTDVGLHQVSAPKFADVDGDADLDAAVVYEWIPAAGAPTMSAYVWTWDGKRAEQVAYPIRGGNDGKLSGLKAKKDGFTITAVSRPYNSPASEQDGERETFTFALEKGFPVQTDPGFGSVDRCVIHDGDPPGAVGDGTAPRVAPESDAPRIGKDGEFASIHTVASVFNTEEWTLARAQRSDGSIGCGWIKTDEATQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2M0</accession>
    <name>D3Q2M0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Recombination protein RecR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recR</name>
        <name evidence="9" type="ordered locus">Snas_6148</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RecR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021342.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6148"/>
    <dbReference type="EnsemblBacteria" id="ADD45771">
        <property type="protein sequence ID" value="ADD45771"/>
        <property type="gene ID" value="Snas_6148"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6148"/>
    <dbReference type="eggNOG" id="COG0353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060739_1_0_11"/>
    <dbReference type="OMA" id="DVMAIEN"/>
    <dbReference type="OrthoDB" id="1661836at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01025">
        <property type="entry name" value="TOPRIM_recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00017">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000093">
        <property type="entry name" value="DNA_Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023627">
        <property type="entry name" value="Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023628">
        <property type="entry name" value="Rcmb_RecR_C4-type_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034137">
        <property type="entry name" value="TOPRIM_RecR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30446">
        <property type="entry name" value="PTHR30446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02132">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111304">
        <property type="entry name" value="SSF111304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00615">
        <property type="entry name" value="recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="79"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="7">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="199" mass="21769" checksum="109D1029810DB425" modified="2010-04-20" version="1">MYEGALGDLVDELGRLPGIGPKSAQRIAFHILGTDKADVDRLAEALRVVKERVRFCEICGNVATEEKCRICRDARRTDEMICVVEEPKDVIAIERTGEFRGRYHVLGGAINPLDGVGPEDLRIRELMTRLQAGVTKELVIATDPNTEGEATATYLALMITPMGLTVSRLASGLPVGGDLEYADEVTLGRAFEGRRTVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2S3</accession>
    <name>D3Q2S3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine triad (HIT) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6201</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021395.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6201"/>
    <dbReference type="EnsemblBacteria" id="ADD45824">
        <property type="protein sequence ID" value="ADD45824"/>
        <property type="gene ID" value="Snas_6201"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6201"/>
    <dbReference type="eggNOG" id="COG0537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056776_3_3_11"/>
    <dbReference type="OMA" id="IAFMDIM"/>
    <dbReference type="OrthoDB" id="1934382at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23089">
        <property type="entry name" value="PTHR23089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="7"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="100"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="141" mass="15241" checksum="12900BE61C07131F" modified="2010-04-20" version="1">MANVSCVFCSIVAGDAPSSVVHEDDVSLAFMDLAPVSDGHTLIVPKAHYAGLEALPEDIGAHLWTVAHRIGRAVRRTPLRCEGVSLTLADGEAAGQDVFHVHLHVFPRYPGDSYRVHADWRQRERPDLDATAALVRAALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Z0</accession>
    <name>D3Q2Z0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0241</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015531.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0241"/>
    <dbReference type="EnsemblBacteria" id="ADD39960">
        <property type="protein sequence ID" value="ADD39960"/>
        <property type="gene ID" value="Snas_0241"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0241"/>
    <dbReference type="eggNOG" id="COG0306">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015355_1_1_11"/>
    <dbReference type="OMA" id="RANPHKA"/>
    <dbReference type="OrthoDB" id="1329125at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD39960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="334" mass="34724" checksum="DAEC4268DF97F25E" modified="2010-04-20" version="1">MDPILIGVIAVVAAAMIFDYTNGFHDAANAIATSVSTRALTPRAALALAAVGNFVGAHLGEGVAKTVGGDLVHIPQEFSGLAVVLAGVLGAITWNLITWWFGLPSSSSHALFGGLVGATLVAGYDVLWAGILEKVIIPMVASPMVGFVLGFIVMIAIMWIFKRKNPRKLSRGFKIAQSVSAAAMSVGHGMQDAAKTMGIIVLALYVGGFQDSNEHIPEWVFYSSAAMLALGTYAGGWRIIKTLGRRVIDLGPPEGFAAETVASGVLYTNALVFEAPISTTHTITSSIMGVGATKGKAAVRWGVAGNIVIAWVLTFPAAAAVAAGVYLLVRPLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Z4</accession>
    <name>D3Q2Z4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4440 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015535.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0246"/>
    <dbReference type="EnsemblBacteria" id="ADD39964">
        <property type="protein sequence ID" value="ADD39964"/>
        <property type="gene ID" value="Snas_0246"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0246"/>
    <dbReference type="eggNOG" id="COG4538">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129336_1_0_11"/>
    <dbReference type="OMA" id="DAWTHES"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027843">
        <property type="entry name" value="DUF4440"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011944">
        <property type="entry name" value="Steroid_delta5-4_isomerase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14534">
        <property type="entry name" value="DUF4440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02246">
        <property type="entry name" value="TIGR02246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049489" description="DUF4440 domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4440" evidence="2">
        <location>
            <begin position="48"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="171" mass="18579" checksum="AEB44F904ACE22BD" modified="2010-04-20" version="1">MRTISKIGAVAAVAVALLGGVATVAVAEGGAAGTTAAQREKEARDALERLRERQFEAWDEKDGAAFASTFAKDGDMVTFNGDHLATRAGIASGMQYYFDNFIEDTTIELLDEKVRFVDGKLAIVVRTTCLVRDGESECRDGSDSVNTNVMAKRHGVWEQQSFQNTRIDPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q324</accession>
    <name>D3Q324_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0276</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0276"/>
    <dbReference type="EnsemblBacteria" id="ADD39994">
        <property type="protein sequence ID" value="ADD39994"/>
        <property type="gene ID" value="Snas_0276"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0276"/>
    <dbReference type="eggNOG" id="COG1607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050164_3_0_11"/>
    <dbReference type="OMA" id="KWIDQAG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040170">
        <property type="entry name" value="Cytosol_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11049">
        <property type="entry name" value="PTHR11049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="4">
        <location>
            <begin position="17"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD39994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="176" mass="18553" checksum="EFF161F8A3C49C21" modified="2010-04-20" version="1">MSTIEAALTAGTGQAPSDSRLTLSSIMSPQDTNLMGTVHGGVILKLIDSVAGVVAARHSQGPAVTASMDETVFLAPVRVGDVAHVDARITWAGRTSMEVAVTVTADRWNETVPATTVATAHLVMVAVDDNGNPRPVPPVVPVSQEDRLAWREAEIRRTHRLALRASLSSKKDDNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q356</accession>
    <name>D3Q356_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR/EmrR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0308"/>
    <dbReference type="EnsemblBacteria" id="ADD40026">
        <property type="protein sequence ID" value="ADD40026"/>
        <property type="gene ID" value="Snas_0308"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0308"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142189_0_0_11"/>
    <dbReference type="OMA" id="RTAFEGH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027395">
        <property type="entry name" value="WH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13601">
        <property type="entry name" value="HTH_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_34" evidence="1">
        <location>
            <begin position="15"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="97" mass="10750" checksum="D94D7DCBDD0CF777" modified="2010-04-20" version="1">MPQPGFDALIHAPTRLSIMAFLIPLDWAEFRLVRDEVGLSDSALSKQITTLEEAGYLEVKKEFQGKRPRTSVRVTDAGRTAFEGHLAALRGIVGDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q365</accession>
    <name>D3Q365_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015606.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0317"/>
    <dbReference type="EnsemblBacteria" id="ADD40035">
        <property type="protein sequence ID" value="ADD40035"/>
        <property type="gene ID" value="Snas_0317"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0317"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047930_0_1_11"/>
    <dbReference type="OMA" id="LQFRGMS"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035418">
        <property type="entry name" value="AraC-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14525">
        <property type="entry name" value="AraC_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="251"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="362" mass="40328" checksum="D6D1F1B6C45E4AFB" modified="2010-04-20" version="1">MSAADYTPSQTGRTRFEVARTMLELPMLSETVPLARYPIFRTTDPVMAAERARTLFCPHRITEIDEPRHFHARQQGVNLRSLSISVLSYHCGVRLRTTELRDRYLILIPLGGAAEINVDGESLAVYPTLGCVVGACGPVRMGWSANCLMLVVRVERGALEAELRERIGGTGPVPIRFESAMDFASGLRAGWWRQLTHLVEDLDADSALPRHPLCVGGLESGLMLGLLVAQPHNHSERLRAAHPAIGEHRIMRAVAILEREPQRPWTTAGLAREAGIGVRALYTDFRRVLDTSPMAYLRNVRLRRVHRELRQPSRNTGVTVAKVATTWGFSHLGEFAAAYRRFYGENPSATLRRAEAATRVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q389</accession>
    <name>D3Q389_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015630.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0341"/>
    <dbReference type="EnsemblBacteria" id="ADD40059">
        <property type="protein sequence ID" value="ADD40059"/>
        <property type="gene ID" value="Snas_0341"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0341"/>
    <dbReference type="HOGENOM" id="CLU_2496408_0_0_11"/>
    <dbReference type="OrthoDB" id="891566at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="86" mass="9644" checksum="4C5052A788BFB90D" modified="2010-04-20" version="1">MANTNITCRHGTTGFCWDDATPDQRKLFDYAHTHAYDWAIERGLARDDAERYAGASAAHTVDVYPDAYSHSLNLVSDLATKYPHVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3K0</accession>
    <name>D3Q3K0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Electron transfer flavoprotein alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2355</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017612.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2355"/>
    <dbReference type="EnsemblBacteria" id="ADD42041">
        <property type="protein sequence ID" value="ADD42041"/>
        <property type="gene ID" value="Snas_2355"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2355"/>
    <dbReference type="eggNOG" id="COG2025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034178_0_1_11"/>
    <dbReference type="OMA" id="WRPYAEQ"/>
    <dbReference type="OrthoDB" id="1400253at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018206">
        <property type="entry name" value="ETF_asu_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00696">
        <property type="entry name" value="ETF_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ETF" evidence="7">
        <location>
            <begin position="4"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="315" mass="32093" checksum="12236B709E3E7A4C" modified="2010-04-20" version="1">MAEVFVVATGANKLTYEMLTLARGLGEVSAVVLGAPGTAASIADNLAEYGAAKIYAAEDEALDKYLVAPKADALAALVTAKSPAAVLVPSTQEGKEIAGRVAVALDNGVLTDVTGLEADGTATQEIFAGATVVKSKVAKGIPLVTVKPNSVTPEPAPATATIEAVEVSVADSSKLVTVEETVVEPKGDRPDLTEANIVVSGGRGVGSAEQFSVIEEFADLLGAAVGASRAATDSGFYPHKFQVGQTGTTVSPQLYVAAGISGAIQHRAGMQTSKTIVAVNKDEGAPIFEIADYGVVGDLFTVLPQAGEEIRKRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3M5</accession>
    <name>D3Q3M5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4294</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4294"/>
    <dbReference type="EnsemblBacteria" id="ADD43942">
        <property type="protein sequence ID" value="ADD43942"/>
        <property type="gene ID" value="Snas_4294"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4294"/>
    <dbReference type="eggNOG" id="COG0645">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111135_0_0_11"/>
    <dbReference type="OMA" id="GTLVMPM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="174" mass="19387" checksum="E962F866B6FDABD8" modified="2010-04-20" version="1">MWINGTFGAGKTTTVTRLTELLPDTLVFDSELVGHLLRHLLRSRPPVGDFQDYPAWRYLVPHTAAQLLAHSGGTLVIPQTVLVEQYWKELMSGFDGLGLTVHHVVLHADRDTLTHRIDNDTAEAGARPWRLDHLDAYERALPWLREAAHVIDTTELAPADTARTIAARLGQAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3N9</accession>
    <name>D3Q3N9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4309</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019527.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4309"/>
    <dbReference type="EnsemblBacteria" id="ADD43956">
        <property type="protein sequence ID" value="ADD43956"/>
        <property type="gene ID" value="Snas_4309"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4309"/>
    <dbReference type="HOGENOM" id="CLU_1299116_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="22509" checksum="5089F0751CA8B1DF" modified="2010-04-20" version="1">MKRSLPALAIASALLLTACGQRGGVDDGEGGAAMDGAEFSSSIDVDGDDVTVEFTLNNTGSGALLAYDRGWVTDPKSPTDEELEPTEDDVQIIVDGDSVEFGLRIIHACHGNPQGEMPPEEVPECETDTATGGRYAATIVEPDRALSREYQFDAASVWPDYPTKLAGTTIDLKGKDVRFCLGVDRPENPADEELYPPEAAETVLCGEAVTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q457</accession>
    <name>D3Q457_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulatory protein, FmdB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6324</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021513.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6324"/>
    <dbReference type="EnsemblBacteria" id="ADD45942">
        <property type="protein sequence ID" value="ADD45942"/>
        <property type="gene ID" value="Snas_6324"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6324"/>
    <dbReference type="eggNOG" id="COG2331">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136025_1_1_11"/>
    <dbReference type="OMA" id="TYQYQCT"/>
    <dbReference type="OrthoDB" id="1914830at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013429">
        <property type="entry name" value="Regulatory_FmdB_Zinc_ribbon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09723">
        <property type="entry name" value="Zn-ribbon_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00834">
        <property type="entry name" value="CxxC_CXXC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02605">
        <property type="entry name" value="CxxC_CxxC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxxC_CXXC_SSSS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="108" mass="11491" checksum="1207D1CFC1BD0A40" modified="2010-04-20" version="1">MPTYQYVCTKCGHDLEARQSFTDKALTDCPSCGIDGALRKQFGSVGVVFKGSGFYRTDSRTGSGKELAKNDSKPAKAASESKSEAKSESKPKTETKKADKPKAASSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4U1</accession>
    <name>D3Q4U1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2438</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017692.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2438"/>
    <dbReference type="EnsemblBacteria" id="ADD42121">
        <property type="protein sequence ID" value="ADD42121"/>
        <property type="gene ID" value="Snas_2438"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2438"/>
    <dbReference type="eggNOG" id="COG1821">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029016_6_2_11"/>
    <dbReference type="OMA" id="GYMSGWT"/>
    <dbReference type="OrthoDB" id="1677960at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041472">
        <property type="entry name" value="BL00235/CARNS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040570">
        <property type="entry name" value="LAL_C2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18130">
        <property type="entry name" value="ATPgrasp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18603">
        <property type="entry name" value="LAL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="115"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="410" mass="42479" checksum="3FFFE0AE47F80CA1" modified="2010-04-20" version="1">MNSAQLVLVESNTTGTGRLFASSGRALGLRPVLLAADPSRYPYVIEDGLECITVDTSDPADVHAVCVGLDKQAPIAAVLSSSEYFVAAAARLAAEFGLPGPAPEAIERCRDKTAQLKALDGAVAVPRYAECATAEAAETAAKELGGDVVVKPCLGSGSEGVRACADPREAADWAATLLAKRHNERGAPIEPRVLVQERVDGPEYSVELLDGEVVGITAKHLGRPPFFVETGHDFPAALPPDRDAAIAASARAAVAALDLLTGPAHVELRYGADGPVLIEVNPRLAGGMIPQLVKLATGFDLITAVVAGASGAPARPEDLAGHHAAIRFLVLDRDGTITAVDGVDNAWETPGVVEVAMIARPGEDRARHHSFRDRLGYVIAIGETTADAATAAEAGRDAVRVALAETGETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5A7</accession>
    <name>D3Q5A7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_4511</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4511"/>
    <dbReference type="EnsemblBacteria" id="ADD44156">
        <property type="protein sequence ID" value="ADD44156"/>
        <property type="gene ID" value="Snas_4511"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4511"/>
    <dbReference type="eggNOG" id="COG0609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013016_1_0_11"/>
    <dbReference type="OMA" id="SWTRNPL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="349" mass="35091" checksum="4A50EF5D75608DDB" modified="2010-04-20" version="1">MFRSAAGSRPRPSPLVAAFAIAVILCGLMVASLLVGGGDVGVGRSLAFLLGDTGARADEHLAMVVTQLRFPRTIVAIITGISLGIAGCVLQTVTRNPLAETGLLGVNAGAALAVVAGISLLAADTAPALLGLALCGALAASAVVLLVASGAKLSPLRLVLAGVALSATFRGATSYLLMSDGAAYDRYRFWVLGSLSGVDLVQVYWVLPAVAGGLLLVLLLIRPLAALSLGDDIAAGLGHRPRRTRILAAAAVTLLTGASVALCGPIAFLGLLAPHLARSLTGPNLARQLLLSGVFGAGIMIAADVAARVVIAPYEAPVSVLLAVIGGPVLILIVRSRRILTLRVPGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5C7</accession>
    <name>D3Q5C7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019747.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4531"/>
    <dbReference type="EnsemblBacteria" id="ADD44176">
        <property type="protein sequence ID" value="ADD44176"/>
        <property type="gene ID" value="Snas_4531"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4531"/>
    <dbReference type="eggNOG" id="ENOG502Z90C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069776_1_2_11"/>
    <dbReference type="OMA" id="DIPDNKP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022183">
        <property type="entry name" value="DUF3710"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12502">
        <property type="entry name" value="DUF3710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="243" mass="26384" checksum="DBB84C8935390A64" modified="2010-04-20" version="1">MFGRKRRRQEEEAVEETVDVVEDDAAPEATTGPYDAADAPEDDEQHLDLGSMRIPALAGLKVGVASDERGNTRPEVVISTEDSVMRLLACAAPRTEGIWDEVRAELAESLSKQGGKVEEIEDGPYGAELRAQQPAGQNDTVTIRFVGIDGPRWFLRVMFQGACATDPEAAPVLDECLRGVVVDRGVEAMPVREPLTLRLTPEMAEQQKKQAESAAATEAPAKANGAERAGARKRKPSPKPRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5C8</accession>
    <name>D3Q5C8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="4">dUTPase</shortName>
            <ecNumber evidence="4">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dut</name>
        <name evidence="7" type="ordered locus">Snas_4532</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>dUTP + H2O = diphosphate + dUMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dUTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019748.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4532"/>
    <dbReference type="EnsemblBacteria" id="ADD44177">
        <property type="protein sequence ID" value="ADD44177"/>
        <property type="gene ID" value="Snas_4532"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4532"/>
    <dbReference type="eggNOG" id="COG0756">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068508_1_3_11"/>
    <dbReference type="OMA" id="YAAFVHP"/>
    <dbReference type="OrthoDB" id="1669228at2"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00116">
        <property type="entry name" value="dUTPase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="PTHR11241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="6">
        <location>
            <begin position="18"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="67"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="84"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="132"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="17237" checksum="9ED5CC1DBD9D20A5" modified="2010-04-20" version="1">MSANDVTVQVRRLDQGLPLPEYAKPGDAGADLYAAGDVTLAPGQRALVPTGVAVALPTGYVGLVHPRSGLAARCGVTVLNAPGTVDAGYRGEIRVNLVNTDTTQPVTLLRGDRIAQLVVQRVERAGFHEVDELPASERGAAGHGSTGGFPQSTGSMNMAATGHGKDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5D9</accession>
    <name>D3Q5D9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Fumarate hydratase class I</fullName>
            <ecNumber evidence="10">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Snas_6383</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible hydration of fumarate to (S)-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the class-I fumarase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021570.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6383"/>
    <dbReference type="EnsemblBacteria" id="ADD45999">
        <property type="protein sequence ID" value="ADD45999"/>
        <property type="gene ID" value="Snas_6383"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6383"/>
    <dbReference type="eggNOG" id="COG1838">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1951">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026758_0_0_11"/>
    <dbReference type="OMA" id="AGVLPMC"/>
    <dbReference type="OrthoDB" id="1627779at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004646">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdA-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004647">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdB-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036660">
        <property type="entry name" value="Fe-S_hydroAse_TtdB_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011167">
        <property type="entry name" value="Fe_dep_fumarate_hydratase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05681">
        <property type="entry name" value="Fumerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05683">
        <property type="entry name" value="Fumerase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001394">
        <property type="entry name" value="Fe_dep_fumar_hy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117457">
        <property type="entry name" value="SSF117457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00722">
        <property type="entry name" value="ttdA_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00723">
        <property type="entry name" value="ttdB_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 10 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumerase" evidence="11">
        <location>
            <begin position="49"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Fumerase_C" evidence="12">
        <location>
            <begin position="331"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD45999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="547" mass="59311" checksum="4AF6264CAC8466B7" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5L0</accession>
    <name>D3Q5L0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, PaaX family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021641.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6455"/>
    <dbReference type="EnsemblBacteria" id="ADD46070">
        <property type="protein sequence ID" value="ADD46070"/>
        <property type="gene ID" value="Snas_6455"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6455"/>
    <dbReference type="eggNOG" id="COG3327">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067515_1_0_11"/>
    <dbReference type="OMA" id="LLIHEYR"/>
    <dbReference type="OrthoDB" id="1210594at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012906">
        <property type="entry name" value="PaaX-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013225">
        <property type="entry name" value="PaaX_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011965">
        <property type="entry name" value="PaaX_trns_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07848">
        <property type="entry name" value="PaaX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08223">
        <property type="entry name" value="PaaX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020623">
        <property type="entry name" value="PaaX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PaaX" evidence="1">
        <location>
            <begin position="5"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="PaaX_C" evidence="2">
        <location>
            <begin position="169"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD46070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="28112" checksum="7BB73DCAF8C11724" modified="2010-04-20" version="1">MASSPRSLIVTVFGLYAREAGGTLPVSGLVRVLATLSVDTQAVRAAVSRLKRRGMLEPSKVDGAAGYALTGSGRRLLAEGDARIFHPPRAELSDGWVLCVFSVPETMRAKRHVLRGKLTWLGFGQAAPGVWIAPAHTMDAARAMLAANDLAGYVNLFRSDYCGDAPVAEAARQWWDLPRLEAMYREFIDALRGDPGADQALPAWIRAVTDWRKLPFLDPGLPRELLPADWPGHDAVTLFGELEADLAPAAAAHARRLLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5L4</accession>
    <name>D3Q5L4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_6459</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6459"/>
    <dbReference type="EnsemblBacteria" id="ADD46074">
        <property type="protein sequence ID" value="ADD46074"/>
        <property type="gene ID" value="Snas_6459"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6459"/>
    <dbReference type="eggNOG" id="COG2119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_769269_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="Gdt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="PTHR12608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD46074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="360" mass="37757" checksum="7BA6D996BD49A2BE" modified="2010-04-20" version="1">MSWVPLFAAFGLIFLAELPDKTMMATLVLSSRYKPIPVLLGVSAAFVVQTAIAVAAGGLLGLLPSWVVLSIVALLFAVGAVLLFRESLASDDDDETGNGRNGLSFWPTVFTSFGVLFAAEWGDASQLGTAALSAHYSAPWEVFTGAALGLITVAALAVVLGRVVVRYVPLKWIQRGAAILFGVFAVIAVVELIRGLGHHCPGMVGGTYGTGRARNARKYRLTGGKAINVTATIEAMPTANPLPIAESTSHIGKCSFRSTSLPLYPSVRDWAAACAKMVRKNSTYPLQHRCQAIAIPPAIHTAIRPPLAPRNANATPPAAIRLSSMLTTTIAIRNPFHTASDCCASLSAAASGGSIPVRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5N8</accession>
    <name>D3Q5N8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Single-stranded nucleic acid binding R3H domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6483</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6483"/>
    <dbReference type="EnsemblBacteria" id="ADD46098">
        <property type="protein sequence ID" value="ADD46098"/>
        <property type="gene ID" value="Snas_6483"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6483"/>
    <dbReference type="eggNOG" id="COG1847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042512_3_0_11"/>
    <dbReference type="OMA" id="MLDIASW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02414">
        <property type="entry name" value="jag_KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02644">
        <property type="entry name" value="R3H_jag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038008">
        <property type="entry name" value="Jag_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039247">
        <property type="entry name" value="KhpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034079">
        <property type="entry name" value="R3H_KhpB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35800">
        <property type="entry name" value="PTHR35800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="SSF82708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H" evidence="4">
        <location>
            <begin position="109"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD46098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="176" mass="19202" checksum="63C6262ECCE8896A" modified="2010-04-20" version="1">MAPISEAETSAAPQADENDTVNTDDLFAESEIAADYLEGFLDIIDSDGDIDELTRGDRPVVEIVGKGLGKLIGQNGATLEALQELARLAVYRKTGEHSRLMLDVGGYRANRRKELTELAEKTVQKVLDSGRMVRLEAMSAFERKCVHDVINATEGVESESEGSEPNRRIVVRPVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5Q4</accession>
    <name>D3Q5Q4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0488"/>
    <dbReference type="EnsemblBacteria" id="ADD40203">
        <property type="protein sequence ID" value="ADD40203"/>
        <property type="gene ID" value="Snas_0488"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0488"/>
    <dbReference type="HOGENOM" id="CLU_1502576_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="179" mass="19714" checksum="7CCFC780DBEB0FD3" modified="2010-04-20" version="1">MSVQQPRTRQAEGEADSYPDPKRSWGRSGSLLGTWGVLLVAVYLAGWMFDGLVDKSPESNLDKPVEDANQTARRVLQFSLVHREPTKADPLLCDGFTGLTPKQLTKELTDWEASEGVLSEATVTFENVNGEAVDGGTLFPMRVELEVDPSFIVWNYDVTVKPDGDSFCVSKVENVTSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5Z2</accession>
    <name>D3Q5Z2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zf-CGNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015862.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0577"/>
    <dbReference type="EnsemblBacteria" id="ADD40291">
        <property type="protein sequence ID" value="ADD40291"/>
        <property type="gene ID" value="Snas_0577"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0577"/>
    <dbReference type="eggNOG" id="COG5516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087298_1_0_11"/>
    <dbReference type="OMA" id="CTARAKT"/>
    <dbReference type="OrthoDB" id="1770002at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010852">
        <property type="entry name" value="ABATE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023286">
        <property type="entry name" value="ABATE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021005">
        <property type="entry name" value="Znf_CGNR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35525">
        <property type="entry name" value="PTHR35525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11706">
        <property type="entry name" value="zf-CGNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160904">
        <property type="entry name" value="SSF160904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-CGNR" evidence="1">
        <location>
            <begin position="143"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="191" mass="20985" checksum="8E96D516F9538782" modified="2010-04-20" version="1">MEIAHNVIRLAPLITELVNLVTPRWRGGSELPRLPEGRLADAFTALLDSRSAADIRAVSDVETRLTALAWALRDAITAPSPSVMAARVNDMIERYRARPYLVDDMDQPFHIHFDGDGETPVESMGGEFASAVALIVDGYGVERFGSCEAHQCEAVYIDLTRNGSRRYCSSGCTARAKTAAYRKRRAGETGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q612</accession>
    <name>D3Q612_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0597"/>
    <dbReference type="EnsemblBacteria" id="ADD40311">
        <property type="protein sequence ID" value="ADD40311"/>
        <property type="gene ID" value="Snas_0597"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0597"/>
    <dbReference type="HOGENOM" id="CLU_1517031_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="177" mass="19947" checksum="903D36E05B4DF768" modified="2010-04-20" version="1">MGDEDYTGFATDCYNLWKAGHVYIPIVADTYAEASRSLGSIYAWHDGEAMGTNEEDVVFRNKMARGQSEAKQEFKDLRDLIQTILARTSQNLYDVGEVLEDAAKGFADRDKDNANEIGSARDQLDQQIDDYEKKVKEDEKDADRDDEPIAPEGEAETKPDNSRDDSDVVKDILPEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6J9</accession>
    <name>D3Q6J9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polar amino acid ABC transporter, inner membrane subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_4598</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019813.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4598"/>
    <dbReference type="EnsemblBacteria" id="ADD44242">
        <property type="protein sequence ID" value="ADD44242"/>
        <property type="gene ID" value="Snas_4598"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4598"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_0_11"/>
    <dbReference type="OMA" id="IGLHYST"/>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="21"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="242" mass="26477" checksum="358ED2BEA20AA12C" modified="2010-04-20" version="1">MDDFWDGALAAQLWDPLLEGFIIILAVTILASIICLVLGLIVAIALRSGPRWLSAPLFGVMEFIRNTPLLVQLFFAWFGIALAIGVSDTIFTVPTFSIGGWEIGPLDFGGPFFVGVIVLGIHYSTYTAEVYRAGIDGVPKGQWEAITALSLPKRYGWQHVILPQALRRVIPALGNYIISMFKEVPVLIAIGLADMIYKTQEFQAANFAGAVEGYTIAGLIFLAASYPIAVAMRKLENRLEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Q7</accession>
    <name>D3Q6Q7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019871.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4657"/>
    <dbReference type="EnsemblBacteria" id="ADD44300">
        <property type="protein sequence ID" value="ADD44300"/>
        <property type="gene ID" value="Snas_4657"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4657"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_17_2_11"/>
    <dbReference type="OMA" id="TYLGYPM"/>
    <dbReference type="OrthoDB" id="1339160at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="14"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="143"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="366" mass="38804" checksum="D51CC87BDD56E708" modified="2010-04-20" version="1">MPVTEDIAPRSGYRAAIIGTGFMGRVHAGAVRVAGGSVVGLVGSTVDKAAEAVDALGADGVFADAAEAIASPDVDVVHVCTPNHLHSELALAALEAGKHVVCEKPLATDARSAQTLTDAAKRGGRVATVPFVYRFHPMVREARELVRRGSIGTVTLAHGGYLQDWLLRPEDDNWRVDPDIGGRTRAFADIGSHWCDLLEFVTGQRITRLSAQLSTVNPRRGAASATEDIATLQFNTDAGAVGTSVISQVSAGRKNRLHLEVSGSDATLHFDQEQPELLWLGGRQRSSVLVRDPETLTPPAARLAVVPSGHPQGYQDCFNAFVADTRAAIDGETPDGLPTFADGLRAARLAEAVLESARDNAWVEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6T9</accession>
    <name>D3Q6T9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Abortive infection protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015909.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0624"/>
    <dbReference type="EnsemblBacteria" id="ADD40338">
        <property type="protein sequence ID" value="ADD40338"/>
        <property type="gene ID" value="Snas_0624"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0624"/>
    <dbReference type="eggNOG" id="COG1266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064706_0_0_11"/>
    <dbReference type="OMA" id="IWIGESG"/>
    <dbReference type="OrthoDB" id="1623593at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042150">
        <property type="entry name" value="MmRce1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35797">
        <property type="entry name" value="PTHR35797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="286" mass="31574" checksum="BDE5A206FA7795E0" modified="2010-04-20" version="1">MTTRAKGLTWFLVISFVVTWTWILAAYYLFDMSLAEPLPQIGMAFTPALAAIVVRAWITREGFGDAGLAFRWRQCWWLYLAAWLGPLAFAAVGGATAALLGLWEPDLSALDAFVPGLPGWAFVLILMLVVPLLTPIYWGEEFGWTSYLRLRLFPERPISSTLATGLIWAVWHFPLAFTDYVVFGNLAIGLLLWTVSFMFQEIILSWMRLRGGSIWPVSLAHAGNNMVLFLLLGELLHGGNLGVVAVTVMGTVPMALVSLWIIATGRLNHIPTEPAKPSLVDARIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6X4</accession>
    <name>D3Q6X4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Myo-inositol catabolism IolB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015944.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0660"/>
    <dbReference type="EnsemblBacteria" id="ADD40373">
        <property type="protein sequence ID" value="ADD40373"/>
        <property type="gene ID" value="Snas_0660"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0660"/>
    <dbReference type="eggNOG" id="COG3718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066438_0_0_11"/>
    <dbReference type="OMA" id="HGYDLYY"/>
    <dbReference type="OrthoDB" id="1047507at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008880">
        <property type="term" value="F:glucuronate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019310">
        <property type="term" value="P:inositol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024203">
        <property type="entry name" value="Deoxy-glucuronate_isom_IolB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021120">
        <property type="entry name" value="KduI/IolB_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39193">
        <property type="entry name" value="PTHR39193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04962">
        <property type="entry name" value="KduI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036628">
        <property type="entry name" value="IolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04378">
        <property type="entry name" value="myo_inos_iolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="286" mass="31257" checksum="A0DF003C47F73346" modified="2010-04-20" version="1">MNYHLPAFSTSADPYETVITPDSAGWHYSGLLVLTLEPGDTHELSTGDSETLVLPLNGGCVVECEGQTIAVTGRASVFSRVSDFVYLPRDATATISSAAGGRFALPSARCERRLSVRYGAAEDVPVELRGAGQCSRQVNNFCTPDVFPADRLIACEVLTPGANWSSYPPHKHDRAGDGECELEEIYYFEVDGSGMGYQRVYGSDRPIDVLAEVRGGDVVLIPHGWHGPAMATPGYDLYYLNVMAGPGEHRAWLISDDPAHGWIRDTWRDLDIDPRLPLTSTVERRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Y4</accession>
    <name>D3Q6Y4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015954.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0670"/>
    <dbReference type="EnsemblBacteria" id="ADD40383">
        <property type="protein sequence ID" value="ADD40383"/>
        <property type="gene ID" value="Snas_0670"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0670"/>
    <dbReference type="HOGENOM" id="CLU_545018_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="500" mass="53337" checksum="E7F3DEF6513C1524" modified="2010-04-20" version="1">MLSFKTLYEAEFGRITVPANGAQAVGKEFDTAGDQMESHAKRLPGMWEGKDGETAVTLLQDQKVPLEGAGEVFRKTSQVLTDLGSRLKTQQDNVRQTVSEAETRIPAKVNIADGSVTPEPIKNPESYSDAALIRERQRRQSLAKSYANLFKQQLEVARQVDRRAKGYLDRLDQYKDAGKAYNVKVEDKGPGLIKKPEAGLIYKDGKWQPSTEKFPPTHYMSWRKNPQTGKFEPIRDSAGNFVPAFRDPNTGEIIPALVDNRTGRLVTDRQGNPIQVIRDPNYRGDPLNAHLIAANPDADPRTPQNRKPVHPTIKLAEKGVGGEHTWLGDPKGGQSEFLGGDLKHKTTLSSGWNAGAGAEVSDGNAFGKAEIGGNLIKFATEADYGNGPFKAKVGGEALIGANAELEGSIGKDGVNAKAGAFAGAKAKVTGSTEFAGVGVGAEAEGWAGAGAEAEFNLGRGPDGKFHIGGKVGVGLGLGGKVGGNVTIDPKEIVKFANPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q754</accession>
    <name>D3Q754_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TrkA-C domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017896.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2648"/>
    <dbReference type="EnsemblBacteria" id="ADD42325">
        <property type="protein sequence ID" value="ADD42325"/>
        <property type="gene ID" value="Snas_2648"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2648"/>
    <dbReference type="eggNOG" id="COG0490">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116143_1_0_11"/>
    <dbReference type="OMA" id="EGAYFQP"/>
    <dbReference type="OrthoDB" id="941006at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026278">
        <property type="entry name" value="K(+)/H(+)_antiporter_KhtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005028">
        <property type="entry name" value="KhtT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RCK C-terminal" evidence="1">
        <location>
            <begin position="73"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="160" mass="17350" checksum="65343BE66A76004D" modified="2010-04-20" version="1">MDVERTALPGIGLRYEFGTERGRRMGVVTHRSGRRELIVYDPDDPDSTSECVVLSGEEANVLAELLGGARIVERLAELERQADGLVSRQVRIHDGSPFDHRTLGDTQARSRTGASIVAVVRHGEVIASPRPDFRFETGDVVVVIGTEDGTNAVESLLANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7I7</accession>
    <name>D3Q7I7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Clp domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4686</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019900.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4686"/>
    <dbReference type="EnsemblBacteria" id="ADD44329">
        <property type="protein sequence ID" value="ADD44329"/>
        <property type="gene ID" value="Snas_4686"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4686"/>
    <dbReference type="eggNOG" id="ENOG5031PET">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1523200_0_0_11"/>
    <dbReference type="OMA" id="IQDMRTI"/>
    <dbReference type="OrthoDB" id="1959218at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="3">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="153" mass="16642" checksum="338B9BA13D23E334" modified="2010-04-20" version="1">MNAFDKYLHAVIMRAQIEASDEGSPSIEASHLLLAIAAEPDASAQRLLASLGLDRDAIRRALDREFEHSLSVVGVSRASYDLPRATRMPSRPSMGTSAKLALERLVKGYRKKDLRSGHVLLGVLMAEVGTVPRALRLAGIDPDEARTQVKEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7J1</accession>
    <name>D3Q7J1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine-type D-Ala-D-Ala carboxypeptidase</fullName>
            <ecNumber evidence="3">3.4.16.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.16.4" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4690"/>
    <dbReference type="EnsemblBacteria" id="ADD44333">
        <property type="protein sequence ID" value="ADD44333"/>
        <property type="gene ID" value="Snas_4690"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4690"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_2_3_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048297" evidence="1">
        <location>
            <begin position="33"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="49"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="379" mass="41275" checksum="D236918D36B59495" modified="2010-04-20" version="1">MRQVIPRRRLLGAGLAAAVAVPVLGWAGTATAREDAAAKIRSGAEKLCRDGVPGLVYAARSTDWRAVEAVGVADMDSGRPMREHYRSRMASISKTFTAVGVLRLVADGLVDVDALADDYLPGVIDGDRAKRITVRMLLNHTTGIGDYGGVYFEGDSREAVERLRWSRAEPQDSARVGLEQPATNEPGEKFDYSNTNYVLLGMIITKVTGVDAEEWLNREVIRAAGLRDTYFPGTAMRIKGPHSKAYHRFPDGDLGEYSVFRMRWDSTAGSLIATPADVGAFYRALLRGELLPSAQLKQLKTLVPAPDEDHGYGMGLGALKLPGKGLAWFHGGGNPGVHTGAWVSDDGKRSFVYSFNMTGVAYEAIEAWQQDAMRRVLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7V0</accession>
    <name>D3Q7V0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Deoxyribose-phosphate aldolase</fullName>
            <ecNumber evidence="2">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0743</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016026.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0743"/>
    <dbReference type="EnsemblBacteria" id="ADD40455">
        <property type="protein sequence ID" value="ADD40455"/>
        <property type="gene ID" value="Snas_0743"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0743"/>
    <dbReference type="eggNOG" id="COG0274">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053595_3_0_11"/>
    <dbReference type="OMA" id="RYSGPDY"/>
    <dbReference type="OrthoDB" id="1227369at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="PTHR10889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="306" mass="32211" checksum="B987C0FCE752F0C9" modified="2010-04-20" version="1">MTSLLTADAVARVRGLPGVDQVGLEQRAAGLATRSIKTTAKKWAIDTAIRMVDLTTLEGADTPGKVRSLCAKAMRPDPSDPSCPAVAAVCVYPSMVPVAAEAVAGSGVHVASVATAFPSGQAPMEVKIADTKAAVAAGAGEIDMVINRGAFLSGRLDEVYEEIVAVKEACGEAHLKVILETGELATYDNVRAASWLAMYAGGDFIKTSTGKVSPAATLPVTLLMLQAVRDFRDETGRQVGVKPAGGIRATKDAMRYLVTVNEVAGEDWLDPDWFRFGASSLLNDLLMQRQKLATGHYSGPDYVTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q807</accession>
    <name>D3Q807_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl-CoA hydratase 2</fullName>
            <ecNumber evidence="1">4.2.1.119</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Enoyl-CoA hydratase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26526"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57319"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="EC" id="4.2.1.119"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.1.119" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016083.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0800"/>
    <dbReference type="EnsemblBacteria" id="ADD40512">
        <property type="protein sequence ID" value="ADD40512"/>
        <property type="gene ID" value="Snas_0800"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0800"/>
    <dbReference type="eggNOG" id="COG2030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094876_1_0_11"/>
    <dbReference type="OMA" id="ISSGWMT"/>
    <dbReference type="OrthoDB" id="1563802at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC-like" evidence="5">
        <location>
            <begin position="19"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="161" mass="17634" checksum="F41384D6E40516C5" modified="2010-04-20" version="1">MWRSGTGETATIFYEDFTIGREFDLGSTTVDDTEMRGFAGRFDPQWYHLDDELAAAGSFGAVTASGWFTASLFMRMYTDAVLSRAAADASPGLEELRWLAPVYAGDELTGRLTVLDRSPSQSRPGLGTVKLSGVLAAANRETAVLSMRFRGWFGMRGPQRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q818</accession>
    <name>D3Q818_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016094.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0811"/>
    <dbReference type="EnsemblBacteria" id="ADD40523">
        <property type="protein sequence ID" value="ADD40523"/>
        <property type="gene ID" value="Snas_0811"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0811"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088490_0_0_11"/>
    <dbReference type="OMA" id="GWGTWKT"/>
    <dbReference type="OrthoDB" id="1286457at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="274" mass="28378" checksum="8A5E17B142376BFF" modified="2010-04-20" version="1">MWASTKAELHKMVRRGANWFMLAIALVLGLTFAYLVPYAGYVGGDSDIPSADRGLEALLPAEFVGNSIGGLPFFTGAISLILGALAIGNEYGWGTWKTVLTQGPSRLTVFSGKLAALTVANLVLVASGIATSAAASAIIASVEDQAMDWPAFADVALGLGGGWLIAMMWTMMGVTLAVTTRGVAVAVGIGLVWMLAVQNLLVSIAAPLIDWIADAQEWLPGPVAGSLVESLGANPNTPGVAELVSDGHALTVICGYLLLFGVLSGVLLRRRDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Q5</accession>
    <name>D3Q8Q5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidyl-dipeptidase Dcp</fullName>
            <ecNumber evidence="8">3.4.15.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_4856</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.15.5" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4856"/>
    <dbReference type="EnsemblBacteria" id="ADD44497">
        <property type="protein sequence ID" value="ADD44497"/>
        <property type="gene ID" value="Snas_4856"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4856"/>
    <dbReference type="eggNOG" id="COG0339">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001805_4_0_11"/>
    <dbReference type="OMA" id="KNFQSAM"/>
    <dbReference type="OrthoDB" id="1935578at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06456">
        <property type="entry name" value="M3A_DCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034005">
        <property type="entry name" value="M3A_DCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43660">
        <property type="entry name" value="PTHR43660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M3" evidence="7">
        <location>
            <begin position="237"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="691" mass="76851" checksum="EF7D1B3E4F4A3F05" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Q6</accession>
    <name>D3Q8Q6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein tyrosine/serine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020069.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4857"/>
    <dbReference type="EnsemblBacteria" id="ADD44498">
        <property type="protein sequence ID" value="ADD44498"/>
        <property type="gene ID" value="Snas_4857"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4857"/>
    <dbReference type="eggNOG" id="COG2365">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057546_0_0_11"/>
    <dbReference type="OMA" id="YIFRSGM"/>
    <dbReference type="OrthoDB" id="1972497at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026893">
        <property type="entry name" value="Tyr/Ser_Pase_IphP-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13350">
        <property type="entry name" value="Y_phosphatase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="2">
        <location>
            <begin position="135"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="266" mass="28593" checksum="1362524A4B9FE3FE" modified="2010-04-20" version="1">MSDTTEPKLSGSPNLRDLGGYRTGDGRRTRHGLLYRSGSLATLSDADVETLAGMGLRAVVDFRLPGEVSFGGADRLPEGLTPVSLPVGGGSLDGFYSLAKSGDWELINRALGDGKAHRSMIDVYRGFVSKDDDRAGFAAALRRITEGDALPLLFHCTAGKDRTGWLAAIVLKLVGVTRVEIFDDFLLSDLYFLPSAIALMEGLGVSRVEAQVFRPLLSQDPKYLEAAFAEAEGRYGSFEGFVHKGLGVGPEAVERLRSRLLEPDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q912</accession>
    <name>D3Q912_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secretory lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016192.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0910"/>
    <dbReference type="ESTHER" id="stanl-d3q912">
        <property type="family name" value="Fungal-Bact_LIP"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40621">
        <property type="protein sequence ID" value="ADD40621"/>
        <property type="gene ID" value="Snas_0910"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0910"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029538_3_0_11"/>
    <dbReference type="OMA" id="FPAHAND"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triglyceride lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005152">
        <property type="entry name" value="Lipase_secreted"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853">
        <property type="entry name" value="PTHR34853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03583">
        <property type="entry name" value="LIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029171">
        <property type="entry name" value="Esterase_LipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="346" mass="37036" checksum="B12496ECE2E68B3C" modified="2010-04-20" version="1">MAEPRRAAGTLVKVGELPVALWPEHAHQAFRIHYQGMGYRGRPRLISGSVFIPAGAAPATGWPVVGYAHGTCGLADKTAPSRTGFFRLEREFLSGWLRAGFAVAATDYEGLGTPGPHPYLDGVAAADDIVDAVRAARQLDAPVDDQWFAVGYSQGGHAALHAAAMATQYAPELRFNGTAALAPVSYLREQVDAKTALADGPVSAILPFILVGLRAKHPHFDCRDHLDDMGDELADLAERGSLVELFKATKGLTNDDLGATDIDSVPALAEALATHEIPIAALDRPLFIGQGDADVSIRPHLTRRLATELETAGTTIHYRRYDTADHASILEHALDDAVAWTNTVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q959</accession>
    <name>D3Q959_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016239.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0958"/>
    <dbReference type="EnsemblBacteria" id="ADD40668">
        <property type="protein sequence ID" value="ADD40668"/>
        <property type="gene ID" value="Snas_0958"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0958"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_4_0_11"/>
    <dbReference type="OMA" id="IGIFERQ"/>
    <dbReference type="OrthoDB" id="1180629at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="297" mass="33456" checksum="0FF827A290C9ECD2" modified="2010-04-20" version="1">MDVNTIVVTGGAGFVGSQLIRGLVEKYPRAAIVSIDNYFTGRRDAHIDNPRVTYVEDSTVNINKLWANSEFGKPDLVFHLGEYARIPQSFDEPDLVWEYNTWGTKEVVKFCTDNQARLIYAGSSSKFGNDGQDEHLNPYAWTKAKNGELIRNYGDWYGLDYVITYFYNVYGPGQIEQGRYATVIGIFERQYKDGEPLTVVEPGTQTRDFTHIDDTVAGLLVCAEHGKGDGYLIGAGHEWPMLDVAKMFGTEYTLIPAKRGERVRGEADNAKVRALGWEPRQSLDRYIAEFVARTPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9C0</accession>
    <name>D3Q9C0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epoxide hydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2927</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2927"/>
    <dbReference type="MEROPS" id="S33.971"/>
    <dbReference type="EnsemblBacteria" id="ADD42602">
        <property type="protein sequence ID" value="ADD42602"/>
        <property type="gene ID" value="Snas_2927"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2927"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_1_11"/>
    <dbReference type="OMA" id="WPSLFVP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033961">
        <property type="term" value="F:cis-stilbene-oxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EHN" evidence="4">
        <location>
            <begin position="4"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="383" mass="42826" checksum="214AFD3D2D121803" modified="2010-04-20" version="1">MNDIHPYRIDIPESRLADLRDRLDRTRWPHQPAGVGWEYGADVSYMRELVEYWRTTYDWRGHEKLLNSYPQFTTTIDGADVHFIHVRSPEAGALPLIMTHGWPGSIVEFLDVIGPLTDPVAHGGRASDAFHLVLPTIPGYGLSGPTPDTGWTVERIAGAWAELMRRLGYDRYGAQGGDWGYPISHQLGILFSERVVGVHLNALATPRPDDAEYEALTAQERERLDAVDRITFDRTGYSHLQATRPQTLAYALTDSPAGQLAWIAEKFKEWTDSDTVPEDAVSRDRLLTNVMLYWLTGTAGSSSHIYLETMRSGTDPYLQPTATPTGVAVFGGDLVKPVRSLAEKAHNIVHWSEFPRGGHFAAMEQPELMVADVRDFFGELAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9E9</accession>
    <name>D3Q9E9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2956</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018202.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2956"/>
    <dbReference type="EnsemblBacteria" id="ADD42631">
        <property type="protein sequence ID" value="ADD42631"/>
        <property type="gene ID" value="Snas_2956"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2956"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_14_1_11"/>
    <dbReference type="OMA" id="NRISAGW"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022324">
        <property type="entry name" value="Bacilysin_exporter_BacE_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01988">
        <property type="entry name" value="EXPORTERBACE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="212"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="412" mass="43118" checksum="AE8533CD2DCF4DE4" modified="2010-04-20" version="1">MVDARARVRYRDVFGVPEFRALWFAELLSICGDQLARVALSVMVFTATDSAALTGLTYGLTYAPSLVGGILLSGLADRFPRREVMAVTDVVRAGLILLVAIPGLPFWVLCVLVGSVSLLTPVFKAAQIAVLPEILSEERFAAAMAIRQMTIQVAQLLGFAGGGLLIAAVSGQTALVLDAATFLFSALLVRMGLRARPAAASASTRPSWLHSMRQGARLAFTDRGLRTLMLLTWLMAVLTVYEGLAAPYAVALGGGSAVTGLLLTADPLGGVIGAYIFGRWVPAQLRPRLIGPLGILAAACLLGCLLQPGLIASLLLFVVSGGLGTIVVMQATTTFTVAVPDANRGQVMGLSNTGLSTASGLSPLLAGVLADDLGAVETVGWFGLASVAVAVPLAVLWRRVMRSDQHRWVPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9H0</accession>
    <name>D3Q9H0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable cell division protein WhiA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">whiA</name>
        <name evidence="8" type="ordered locus">Snas_2978</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in cell division and chromosome segregation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WhiA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018223.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2978"/>
    <dbReference type="EnsemblBacteria" id="ADD42652">
        <property type="protein sequence ID" value="ADD42652"/>
        <property type="gene ID" value="Snas_2978"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2978"/>
    <dbReference type="eggNOG" id="COG1481">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053282_0_0_11"/>
    <dbReference type="OMA" id="CDAEAAW"/>
    <dbReference type="OrthoDB" id="1634356at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043937">
        <property type="term" value="P:regulation of sporulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01420">
        <property type="entry name" value="HTH_type_WhiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018478">
        <property type="entry name" value="Sporu_reg_WhiA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003802">
        <property type="entry name" value="Sporulation_regulator_WhiA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023054">
        <property type="entry name" value="Sporulation_regulator_WhiA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039518">
        <property type="entry name" value="WhiA_LAGLIDADG_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37307">
        <property type="entry name" value="PTHR37307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02650">
        <property type="entry name" value="HTH_WhiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14527">
        <property type="entry name" value="LAGLIDADG_WhiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10298">
        <property type="entry name" value="WhiA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00647">
        <property type="entry name" value="DNA_bind_WhiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WhiA_N" evidence="6">
        <location>
            <begin position="19"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="LAGLIDADG_WhiA" evidence="7">
        <location>
            <begin position="127"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_WhiA" evidence="5">
        <location>
            <begin position="221"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="34583" checksum="D9166632C3800764" modified="2010-04-20" version="1">MAMTASVKDELSRIDNSKPCCRRSEMSALFRFAGGLHLVGGSLVVEAELDAGSVARRLRAAIQDAYGYDSEMQVLTAGGLRRHTHYVLRVINDGEALARQTGLLDARGRPVRGLPAHVVAGNLCCAEAAWRGAFMAHGSLTEPGRSSSLEITCPGPESALALVGAARRLGITAKARDARGVDRVVIRDGDAIGQLLVRLGAHAGVLAWEERRVRREVRATANRLANFDDANLRRSARAAVAAAAKVSRALELLGDEVPGHLAEAGRLRLANRQASLEELGAMADPPLTKDAIAGRIRRLINLANKHAAAAGEPPVEAVVTDEMLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9J1</accession>
    <name>D3Q9J1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018244.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3001"/>
    <dbReference type="EnsemblBacteria" id="ADD42673">
        <property type="protein sequence ID" value="ADD42673"/>
        <property type="gene ID" value="Snas_3001"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3001"/>
    <dbReference type="eggNOG" id="COG2188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063236_2_2_11"/>
    <dbReference type="OMA" id="FAPRYFR"/>
    <dbReference type="OrthoDB" id="1775418at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="236" mass="25951" checksum="D9312E282F1C7EA4" modified="2010-04-20" version="1">MAETQTPRYHAIEQALRQRIRDLPAHTALPSESRLSAEFGVSRMTARGAVTRLVNAGLVYRMSGRGTFVAPPPSNRRADSLIRFTEQMRRSGRTATSRLLGTDTRAATEAERTDLRPGKNGVIEIRRIRLADATPIAVETAVFSATLSRLLDTDLSVSLHTQLARLGRVPTSGHATVTAESATVTDADLLDIPAGSAVLVERRLINDQHGHPLERTESRYAAERYRLDVVFDVDQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9K6</accession>
    <name>D3Q9K6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020123.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4911"/>
    <dbReference type="EnsemblBacteria" id="ADD44552">
        <property type="protein sequence ID" value="ADD44552"/>
        <property type="gene ID" value="Snas_4911"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4911"/>
    <dbReference type="HOGENOM" id="CLU_121293_0_0_11"/>
    <dbReference type="OrthoDB" id="2050869at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="176" mass="19897" checksum="C2FAF3D9DC78E623" modified="2010-04-20" version="1">MGEIADSLAGLTISVVSPDNQLAATVRRRREVTVHFRPGSYERYDARTLETQLSQLFTLVMSGYRQGYMSVMEAHDMTVMADASDVDTEAGRIVRRRRDETVALGESAQGMVRAKTRGLSEWRFKIADGALSRLSEEQFTAEIHGAFMNVMADWSRRVRRIHWEVFSPDRVPAAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9N5</accession>
    <name>D3Q9N5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020152.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4940"/>
    <dbReference type="EnsemblBacteria" id="ADD44581">
        <property type="protein sequence ID" value="ADD44581"/>
        <property type="gene ID" value="Snas_4940"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4940"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_2_2_11"/>
    <dbReference type="OMA" id="AMIPAFF"/>
    <dbReference type="OrthoDB" id="1425840at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="11"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="144"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="303" mass="31321" checksum="2B55EA6AC6958522" modified="2010-04-20" version="1">MNRELRDIAITALAPVMWGTTYIVTTELLPPGRPLLTALLRALPAGLLLVVLARKLPQGSWWWKASVIGALNIAAFFALLFIAAYRLPGGVAAVVSAIGPLVTAGMTILILNQKVRLRTWLLGIAGVAGVAMVMLNAAAKLDALGMIAGLAAATSMAVATTLTKRWGAPTGAGSAALAGWQLTAGGLFLLPFALIIEGGIPALSLTNVAGYVYLGLVNTALGYWLWFRGISRLSVAPLSFLGLLSPLTAATVGWIVLGEALTPLQLLGMVVAFGATVAGQLTSVRRPAVVPQATPRAELAKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9V6</accession>
    <name>D3Q9V6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Male sterility domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020223.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5015"/>
    <dbReference type="ESTHER" id="stanl-d3q9v6">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44652">
        <property type="protein sequence ID" value="ADD44652"/>
        <property type="gene ID" value="Snas_5015"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5015"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_460527_0_0_11"/>
    <dbReference type="OMA" id="QNGQHNH"/>
    <dbReference type="OrthoDB" id="81004at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="Far_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_4" evidence="1">
        <location>
            <begin position="15"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="389"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="667" mass="70037" checksum="841719801DA5DC79" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAL4</accession>
    <name>D3QAL4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">L-fucose isomerase 2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_3126</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018368.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3126"/>
    <dbReference type="EnsemblBacteria" id="ADD42797">
        <property type="protein sequence ID" value="ADD42797"/>
        <property type="gene ID" value="Snas_3126"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3126"/>
    <dbReference type="eggNOG" id="COG2407">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039041_0_0_11"/>
    <dbReference type="OMA" id="VWQYSHH"/>
    <dbReference type="OrthoDB" id="507566at2"/>
    <dbReference type="UniPathway" id="UPA01068">
        <property type="reaction ID" value="UER00304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008736">
        <property type="term" value="F:L-fucose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.14.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004216">
        <property type="entry name" value="Fuc/Ara_isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038393">
        <property type="entry name" value="Fuc_iso_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015888">
        <property type="entry name" value="Fuc_isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038391">
        <property type="entry name" value="Fucose_iso_dom1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012888">
        <property type="entry name" value="Fucose_iso_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038392">
        <property type="entry name" value="Fucose_isomerase_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009015">
        <property type="entry name" value="Fucose_isomerase_N/cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012889">
        <property type="entry name" value="Fucose_isomerase_N2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02952">
        <property type="entry name" value="Fucose_iso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07881">
        <property type="entry name" value="Fucose_iso_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07882">
        <property type="entry name" value="Fucose_iso_N2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50443">
        <property type="entry name" value="SSF50443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53743">
        <property type="entry name" value="SSF53743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fucose_iso_N1" evidence="7">
        <location>
            <begin position="2"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Fucose_iso_N2" evidence="8">
        <location>
            <begin position="160"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Fucose_iso_N2" evidence="8">
        <location>
            <begin position="252"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Fucose_iso_C" evidence="6">
        <location>
            <begin position="330"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="470" mass="52065" checksum="A1816CD17058FE5F" modified="2010-04-20" version="1">MARIGVISISDGREYVQKDIGDFIAGYEDRLVASLEAAGHEVIRGEEQVTSNTVATAVARRVAARGVDLTVLHYAVWAFPHFTMLAADASPGPLLLLSTIDPAQPGMVGMLAAGGALDQIGREHTRLWGDADDTELIDAIGVRASAAAAVSSLRGSTFGRIGGRPMGMYTAVANTDQWQREFGIDVEEIDQYEIVRRAELADASEKKHAREWLETNANVHYDGKKLTPELLERQIGSYMAMRELIEEWNLDFTGIKGQPELTQYFATMDIAEAFLNDPYDWNGPKAPHVCATEADMDGALTMQLLKGITGTPVLFADVRHYHADRDVWDLCNSGQHATWYAARSDDPAVNLARVHLYPEVFFFPAGGASVHHIAAPGEMTLARLTRLDGKYRMQLMHGEFQEFDDEVNTEMMRRSTPEWPHAWARIHAPAATFLSRFGANHIHAVPGDRRAELRTVCELMGISLDEFTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAM1</accession>
    <name>D3QAM1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018375.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3133"/>
    <dbReference type="EnsemblBacteria" id="ADD42804">
        <property type="protein sequence ID" value="ADD42804"/>
        <property type="gene ID" value="Snas_3133"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3133"/>
    <dbReference type="HOGENOM" id="CLU_1229267_0_0_11"/>
    <dbReference type="OrthoDB" id="2154782at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="225" mass="24374" checksum="FA3A72D6E942E515" modified="2010-04-20" version="1">MTPTQQRLQPFYLAVPFTAVITGLFNLSETLPAPLALLAGAAWGIVLGLIATWLNTKATLSAWLEDGFVYLGIVGFAFAGCGGLMAILMLDGALGASSLTAEALEALFLPSIPYYIVVNSALELLVIPGLLYFGWRAGKRRVLILAAAGLYFAMRVWTYLAFVPARMGWAEAEHSGEALSAAERRQAASDLMVDDPRWILLLVMLAILLVAAYLPRVRERKTRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAN5</accession>
    <name>D3QAN5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020252.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5044"/>
    <dbReference type="EnsemblBacteria" id="ADD44681">
        <property type="protein sequence ID" value="ADD44681"/>
        <property type="gene ID" value="Snas_5044"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5044"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_5_11"/>
    <dbReference type="OMA" id="CARHFRS"/>
    <dbReference type="OrthoDB" id="1377545at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="286" mass="31267" checksum="04F2534BD089B41A" modified="2010-04-20" version="1">MSLNSEREPRTIVITGGTDGMGKALGLHYLRRGDRVVAIGTDADKGARFEAEAEALDARDRATFLRADLSLVAENNRVLAELTTRFPSLDAVILGARYYRSTRAETPEGIEHNFALFYLSRYLFSHGLVEPLARNENPVILNLAGPGGELSALNWDDPQFRRGYRPDLVMAQCGKLCDLLGVDFTLANPDTHIRYVLAHPGLTASGFTGQYSPADAELVAAMRERGQPLDVAVDMLRRHIDDPDPEPLSAYMQHDKLDVTGPAFDPTAARRLAGYATRTLSAVASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAT3</accession>
    <name>D3QAT3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Shikimate dehydrogenase (NADP(+))</fullName>
            <shortName evidence="3">SDH</shortName>
            <ecNumber evidence="3">1.1.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">aroE</name>
        <name evidence="6" type="ordered locus">Snas_5094</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>NADP(+) + shikimate = 3-dehydroshikimate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17737"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the shikimate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.25" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020300.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5094"/>
    <dbReference type="EnsemblBacteria" id="ADD44729">
        <property type="protein sequence ID" value="ADD44729"/>
        <property type="gene ID" value="Snas_5094"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5094"/>
    <dbReference type="eggNOG" id="COG0169">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044063_4_3_11"/>
    <dbReference type="OMA" id="HEHEGDA"/>
    <dbReference type="OrthoDB" id="1054867at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00087"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00222">
        <property type="entry name" value="Shikimate_DH_AroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="PTHR21089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate_dh_N" evidence="4">
        <location>
            <begin position="11"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_C" evidence="5">
        <location>
            <begin position="271"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate binding" evidence="3">
        <location>
            <begin position="19"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="135"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="31956" checksum="8B205F87B440C89B" modified="2010-04-20" version="1">MTAHDGYLIGLIGSGIGPSLSPALHEREAAELGLRYLYRRLDLAATGRGPGACVEVLAAARLAGYDGLNITHPCKQLVIPHLDELSADAAALGAVNTIDLSGGRAVGHNTDWSGFSRAFTLGLPEAAIERVVVLGAGGAGAAVAHALLTLGANRIELFDRVAERSHELAAKLSNHFGAGRVVAGRLGGDGALATAPTAGQPFGEADGLAAALAVADGLVHATPTGMSAHPGLPLSVELLRPQCWVAEVVYRPLQTPLLAAARARGCRVLDGGRMAVFQAAESFRLFTGAEPDPDRMSRHFQDLIGAESHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAY0</accession>
    <name>D3QAY0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5141</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5141"/>
    <dbReference type="EnsemblBacteria" id="ADD44776">
        <property type="protein sequence ID" value="ADD44776"/>
        <property type="gene ID" value="Snas_5141"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5141"/>
    <dbReference type="eggNOG" id="COG1236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009673_5_1_11"/>
    <dbReference type="OMA" id="YLDGMIW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="148"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="3">
        <location>
            <begin position="383"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="51"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="577" mass="61244" checksum="3907CEABA669C60A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB19</accession>
    <name>D3QB19_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-xylose-binding periplasmic ABC transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1126</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1126"/>
    <dbReference type="EnsemblBacteria" id="ADD40836">
        <property type="protein sequence ID" value="ADD40836"/>
        <property type="gene ID" value="Snas_1126"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1126"/>
    <dbReference type="eggNOG" id="COG4213">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_13_3_11"/>
    <dbReference type="OMA" id="YTDGWLP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049709" evidence="1">
        <location>
            <begin position="34"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="46"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="367" mass="39002" checksum="BA421EBAD8F40D0A" modified="2010-04-20" version="1">MRSSARPAAAKGFRLLALTCAAALGVAGMSACGDDSGTGEAKIGVILPDSKSSPRWETADRKYLEAAFKKADVDYDIQNAQGDKTDFQTIADQMITNGATVLMIVNLDSGTGKAVLKKARAQGVATIDYDRYTIEGKADYYVSFDNVAVGKQNAEGLVECLKEKKVKKPVIAELNGAPTDNNATLFKEGYDSVLDPLYDSGEFVKGPDESVPEWDGTQAGTIFEQMMTEKKNKIDGVLAANDTLAHAAISVLKKNKLGGEVPVSGMDASTQGLQNVLTGDQCLTVYKPVKQEADAAAELAISLAEGKKEKLDDTLTDPETGHKTPSVFLKAQIITAENVQDVVDDGYVTAEKLCKDIAAECEKAGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB28</accession>
    <name>D3QB28_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1135"/>
    <dbReference type="EnsemblBacteria" id="ADD40845">
        <property type="protein sequence ID" value="ADD40845"/>
        <property type="gene ID" value="Snas_1135"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1135"/>
    <dbReference type="eggNOG" id="ENOG50307VP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095244_1_0_11"/>
    <dbReference type="OMA" id="QHADREP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025339">
        <property type="entry name" value="DUF4245"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14030">
        <property type="entry name" value="DUF4245"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="198" mass="21064" checksum="41F249EB06255103" modified="2010-04-20" version="1">MNRVGGLCYASIGENRSMSTEAGPAPKRGRLTARRPRDMIISLAILLVPIGLIFVGWRFLMGDQDVNPVDFSETVGEAERAGLPVVEPDGLSGDWVPISHSVDEEKGAVTLRIGYLTPDEAGLQLVESDAKPDAVIDAALGEESPTKTGSTEVAGREWQTYTTADGHSAFVSTDDDMTIAVVGDAASRELKEFTAALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB72</accession>
    <name>D3QB72_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016460.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1179"/>
    <dbReference type="EnsemblBacteria" id="ADD40889">
        <property type="protein sequence ID" value="ADD40889"/>
        <property type="gene ID" value="Snas_1179"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1179"/>
    <dbReference type="HOGENOM" id="CLU_865758_0_0_11"/>
    <dbReference type="OMA" id="SEGMKWE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="293"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="321" mass="31468" checksum="50B0F1226F9354B3" modified="2010-04-20" version="1">MTTQQPDDRTPTSPARPDPAAPGQPSASEPTSAPGSTPPPQDRPAPESPVARPSLQATEPTPADDLPQAPAAPAADVTPPPETAPAVAEPTAEGESEVASDDVPHAAAEPVAEPTSDVTPQPAEAPAVSDAGDAPADAEPPVEMTPPGESPSGAADAAAAEEAAKAEADSPVDAPVTGGSMPIPMPPVSRPPAGSAYGYPTRYAEAPGSGHFQLALPQLGTIVAGPAAGSMIAGIAAILVAFSVGCTGMFGSVMVPVAATVLAVFFISTAGLLAAVALRQIRRGGGEYRGKGMAIAGLACGGAAILVLLFMLLLVTVALSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB83</accession>
    <name>D3QB83_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 11">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplV</name>
        <name evidence="13" type="ordered locus">Snas_1190</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="7">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="8 11">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 10">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016471.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1190"/>
    <dbReference type="EnsemblBacteria" id="ADD40900">
        <property type="protein sequence ID" value="ADD40900"/>
        <property type="gene ID" value="Snas_1190"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1190"/>
    <dbReference type="eggNOG" id="COG0091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083987_3_2_11"/>
    <dbReference type="OMA" id="KRIQPRA"/>
    <dbReference type="OrthoDB" id="1666043at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_L22/L17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="118"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD40900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="158" mass="17257" checksum="7D231700E601A7EB" modified="2010-04-20" version="1">MASNEATLAPSARAVARYVRVSPMKARRVVNLVRGLPADEALTVLQFAPQAASEPVYKVIASAIANAENNEKLDRESLLVSEAFVDEGPTMKRYRPRAHGRAYRIRKRTSHITVVLESVQASEQPSGTIRRPKRSASKSTKPAAAEPTSTDTAEKETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBF0</accession>
    <name>D3QBF0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <shortName evidence="11">AdoMet synthase</shortName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">MAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Methionine adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">metK</name>
        <name evidence="17" type="ordered locus">Snas_3161</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 13">Belongs to the AdoMet synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018403.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3161"/>
    <dbReference type="EnsemblBacteria" id="ADD42832">
        <property type="protein sequence ID" value="ADD42832"/>
        <property type="gene ID" value="Snas_3161"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3161"/>
    <dbReference type="eggNOG" id="COG0192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041802_1_1_11"/>
    <dbReference type="OMA" id="EFTWEMP"/>
    <dbReference type="OrthoDB" id="1024388at2"/>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="PTHR11964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="SSF55973"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10 11 12" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-AdoMet_synt_N" evidence="14">
        <location>
            <begin position="4"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_M" evidence="15">
        <location>
            <begin position="126"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_C" evidence="16">
        <location>
            <begin position="246"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Flexible loop" evidence="11">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="175"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="243"/>
            <end position="244"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="258"/>
            <end position="259"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ADD42832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="396" mass="42253" checksum="CF4F6BE21C6AEE27" modified="2010-04-20" version="1">MARRLFTSESVTEGHPDKIADQISDGILDALLTEDPASRVAVETLITTGQVHVAGEVTTGAYADIPSIVRETILGIGYDSSKKGFDGASCGVSVSIGSQSPDIAQGVDKALESREDASDHDALDLQGAGDQGMMFGFACGETPELMPLPIALSHRLSQRLSAVRKDGTVPYLRPDGKTQVTIEYDDLKPVKLNTVVVSSQHAPDVSLDSLMTPDIAEHVVAPELKALDIDVSDFRLLVNPTGRFEIGGPMGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLAERCETQVAYAIGKAHPVSVRVETFGTETIPVAKIEEAIGKVFDLRPAAIIRDLNLLRPIYRQTAAYGHFGRELPELSWETTDRVDALKAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBS3</accession>
    <name>D3QBS3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020383.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5177"/>
    <dbReference type="EnsemblBacteria" id="ADD44812">
        <property type="protein sequence ID" value="ADD44812"/>
        <property type="gene ID" value="Snas_5177"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5177"/>
    <dbReference type="eggNOG" id="COG3920">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045351_1_0_11"/>
    <dbReference type="OMA" id="GSIAIVH"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038424">
        <property type="entry name" value="H_kinase_PdtaS_GAF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022066">
        <property type="entry name" value="PdtaS_GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011495">
        <property type="entry name" value="Sig_transdc_His_kin_sub2_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12282">
        <property type="entry name" value="H_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07568">
        <property type="entry name" value="HisKA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="299"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="492" mass="53654" checksum="1D15C14B86261C18" modified="2010-04-20" version="1">MSTLGDLIAAHTDLSANTSEHLHRLAAEWQLLADLSFADLLLWAPVRDREGCYICLAQVRPTTGPTAYDDDQVGRVLSGKDAEHLHTSFSEGRIFREGDPVWHGATPARHEAVPVRRRDRQQVVAVVARDTNLSDTRSPSHLELNYLKTADYLIRMLTDGGFPPPLLPGEPTTAPRVGDGLVRIGADGLVRYASPNALSAYRRMGVTGVLSGENLAELTRGLVDDPEKAKDVHRRINRALSGETPRRKEIEARGAVVLVRALPLRPDGQGAGALVLVRDVTEVRRLDRELVTKEATIREIHHRVKNNLQTVAALLRLQARRVGVPQARAALEESVRRVTSIALVHETLSRSSDEAVSFDAIVDKVASMAAEVAAPESQVRPRRVGNFGVLPSEVATPLVMILNELVQNAVEHAYPPGQGGEVVVDVQREGDRLQVTVYDHGRGLPEGFRIDATHRLGLQIVHTLATGELRGTIKLGNREDGGAEAVLDFTIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBU1</accession>
    <name>D3QBU1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5195"/>
    <dbReference type="EnsemblBacteria" id="ADD44830">
        <property type="protein sequence ID" value="ADD44830"/>
        <property type="gene ID" value="Snas_5195"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5195"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065119_1_0_11"/>
    <dbReference type="OMA" id="RTTVHHS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="322" mass="33397" checksum="E8A138264F1FEFDE" modified="2010-04-20" version="1">MALALGWIFLGTMVISYGVANFLQAVATGREQRHESLNPRLLLKLASQKTYLTGIAFQILGFLLAIAARADLPLFLVQAAVAAGLGVTAVLGVVLLKWRLPKAEIALLIGLSLGIVMLVISAKPSASKDLDLVAILALAGSWVLIAVAGWFTARKLHGVPGSVALGALAGLSFGAAAVASRPLASAVGVTGLLSDPLLYVIIVQSLTGQLLLALAMQRGSATAAVAAMDAAFAVPAAAVGLLLLGDQIRPNLEWLAATGFLVTLGTVLALTRYAQPQQHTAAIARWRSRPSELEASVDVHASDLFPPTDDGAPDPMREPSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBY3</accession>
    <name>D3QBY3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5238</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="ADD44872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44872">
        <property type="protein sequence ID" value="ADD44872"/>
        <property type="gene ID" value="Snas_5238"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5238"/>
    <dbReference type="eggNOG" id="ENOG502ZUJ3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1309484_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:transmembrane transporter activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
    </dbReference>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
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            <end position="36"/>
        </location>
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            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="210" mass="20855" checksum="97A9E869E5580CBF" modified="2010-04-20" version="1">MYPPTQGEAAAPRPFHRLLFLVGGGLAAVIGAYLLTAPLAPGGATITTAIGIQPAVALPMMLLGFLIPAAVGAALGFFARRFPAIVAIVGIAVMAIGISVSGIAPNFLLLVAGSVVTGFGAGAVWGSVTVVALAAGGNKVVELSVLGGAVVLALAVGPFVSGAINMSLSFRIGHYMTVPPLLVALVIAIIAAAARDNRTMPQQTTVQPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC22</accession>
    <name>D3QC22_STANL</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ordered locus">Snas_5277</name>
    </gene>
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        <lineage>
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            <taxon>Actinobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
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                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
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            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ADD44911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5277"/>
    <dbReference type="EnsemblBacteria" id="ADD44911">
        <property type="protein sequence ID" value="ADD44911"/>
        <property type="gene ID" value="Snas_5277"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG3647">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087528_0_0_11"/>
    <dbReference type="OMA" id="WDTQWDM"/>
    <dbReference type="OrthoDB" id="1341485at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014509">
        <property type="entry name" value="UCP020606"/>
    </dbReference>
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        <property type="entry name" value="DUF2238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020606">
        <property type="entry name" value="UCP020606"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="12"/>
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        </location>
    </feature>
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        <location>
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            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
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        <location>
            <begin position="104"/>
            <end position="124"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="24620" checksum="6BCE6E6FB30BBBAA" modified="2010-04-20" version="1">MTTPEIRTPGRAEGWVLVGIVLAVLVWSGIGPNSLGTWALEIAWVVAGLVIIPLCWRRFPLSRLLCWLLAIHAVILIYGGHYTYAETPLGDWVRDLLDLRRNNYDRLGHFVQGFIPAILFRELLLRKGPLRPGKLLFVLVTACGLAFSAFFEMIEWWAALILGADAEAYLATQGDVWDTQWDMFLALCGAALSQLLLSRWHDRQLGLSGRIPTAVPAGTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTX6</accession>
    <name>D3PTX6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_0011</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="OrthoDB" id="643917at2"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="41"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="360"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="393"/>
            <end position="400"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD39734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="608" mass="65922" checksum="DAD4EA41DAB0D147" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUA2</accession>
    <name>D3PUA2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016619.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1340"/>
    <dbReference type="EnsemblBacteria" id="ADD41048">
        <property type="protein sequence ID" value="ADD41048"/>
        <property type="gene ID" value="Snas_1340"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1340"/>
    <dbReference type="eggNOG" id="ENOG5033F74">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174878_0_0_11"/>
    <dbReference type="OMA" id="QWIVVVE"/>
    <dbReference type="OrthoDB" id="1895616at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="87" mass="9180" checksum="077A7101C3B5284B" modified="2010-04-20" version="1">MRADTTPRLLVTPDRDSAESAAEAITDAGLAPAPPRVVREALAGEDDAEDAQWLAVVEAPSQGWNAETLAALDDIASDHEGWLEIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV72</accession>
    <name>D3PV72_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome maturation factor RimP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rimP</name>
        <name evidence="6" type="ordered locus">Snas_1418</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for maturation of 30S ribosomal subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RimP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016696.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1418"/>
    <dbReference type="EnsemblBacteria" id="ADD41125">
        <property type="protein sequence ID" value="ADD41125"/>
        <property type="gene ID" value="Snas_1418"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1418"/>
    <dbReference type="eggNOG" id="COG0779">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070525_3_0_11"/>
    <dbReference type="OMA" id="TEHRHYV"/>
    <dbReference type="OrthoDB" id="1595498at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01734">
        <property type="entry name" value="YlxS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01077">
        <property type="entry name" value="RimP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003728">
        <property type="entry name" value="Ribosome_maturation_RimP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028998">
        <property type="entry name" value="RimP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028989">
        <property type="entry name" value="RimP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035956">
        <property type="entry name" value="RimP_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33867">
        <property type="entry name" value="PTHR33867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02576">
        <property type="entry name" value="DUF150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17384">
        <property type="entry name" value="DUF150_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75420">
        <property type="entry name" value="SSF75420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="DUF150" evidence="4">
        <location>
            <begin position="13"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="DUF150_C" evidence="5">
        <location>
            <begin position="92"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="162" mass="17767" checksum="25F9B145245E0CDB" modified="2010-04-20" version="1">MADVTRKRILAVLEPVLAEAGYDLEELKVSQAGRRTLVRVLVDRDAGVDLDAIASVSRVLSKALDKSEADDGPFATNSYTLEVSSPGVDRPLTLPRHWRRNVGRLVSVRLSDATVTARIHAADDENVELELSDGTRRVAYGDLGPGRVQLEFSRSASKERQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVJ8</accession>
    <name>D3PVJ8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CoA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3448</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018683.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3448"/>
    <dbReference type="EnsemblBacteria" id="ADD43112">
        <property type="protein sequence ID" value="ADD43112"/>
        <property type="gene ID" value="Snas_3448"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3448"/>
    <dbReference type="eggNOG" id="COG0045">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1042">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007415_3_0_11"/>
    <dbReference type="OMA" id="VARMTQI"/>
    <dbReference type="OrthoDB" id="445933at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043758">
        <property type="term" value="F:acetate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043938">
        <property type="entry name" value="Ligase_CoA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032875">
        <property type="entry name" value="Succ_CoA_lig_flav_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19045">
        <property type="entry name" value="Ligase_CoA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13607">
        <property type="entry name" value="Succ_CoA_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="22"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="681"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="898" mass="94377" checksum="FB94F6B36CAACD93" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVK2</accession>
    <name>D3PVK2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018687.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3452"/>
    <dbReference type="EnsemblBacteria" id="ADD43116">
        <property type="protein sequence ID" value="ADD43116"/>
        <property type="gene ID" value="Snas_3452"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3452"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_2_3_11"/>
    <dbReference type="OMA" id="ECEPAMA"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="9"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="153"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="289" mass="30305" checksum="40A0E3BF14579A59" modified="2010-04-20" version="1">MNENSPAPVVVGVDGSDDSPSTVILAAAYAADRQSPLRIVHARAWPTYTGNPPLLTPPVAPIEDEPTARLIVDNARDLVRGVHPDVNVTGHVIDGGPAVVLIDESRHATLVVVGSHGHGGLARRALGSTAMDVAARATCPVLVVRGEVTRNGPVVVGVDGRGTSKAAIDFAFAEARARSVPLRAVHAWHHSTNLVDTAESEADGRQRARSVLDEWLSDDRGNFGDVVVETVPVHQANPARALGEESAKASLVVLGSRMRGALRSRLLGSTGYAMVHTSQCPVVIVRSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW28</accession>
    <name>D3PW28_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5518</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020720.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5518"/>
    <dbReference type="EnsemblBacteria" id="ADD45149">
        <property type="protein sequence ID" value="ADD45149"/>
        <property type="gene ID" value="Snas_5518"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5518"/>
    <dbReference type="eggNOG" id="COG1053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014312_8_1_11"/>
    <dbReference type="OMA" id="PTAHHFM"/>
    <dbReference type="OrthoDB" id="153138at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033765">
        <property type="term" value="F:steroid dehydrogenase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="3">
        <location>
            <begin position="10"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="4">
        <location>
            <begin position="488"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="641" mass="70228" checksum="F049C5BE54D11B56" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW33</accession>
    <name>D3PW33_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020725.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45154">
        <property type="protein sequence ID" value="ADD45154"/>
        <property type="gene ID" value="Snas_5523"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5523"/>
    <dbReference type="eggNOG" id="ENOG5032205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097550_0_0_11"/>
    <dbReference type="OMA" id="WFGWAQE"/>
    <dbReference type="OrthoDB" id="1942018at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="180" mass="19344" checksum="7BB9F16E2E87A0FD" modified="2010-04-20" version="1">MLTDYLRDALFTAAWFGLMTGVWLGWAQEDPPRRWRGWLGAGSVLGIACALGFGAATGLNWGLDSALEGKYQWFGVLVTVEVVLAGGGCWWLARTRRSRWMAWWVAVVVAAHFLPLGWMLDDASIAVAGVVQLVALGALVPRLRRTKRTTSALVGAVMGGTLLAYALITAAVTLPVLLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW50</accession>
    <name>D3PW50_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative aminoacid/polyamine transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1503</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
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                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="entry name" value="AA_permease_2"/>
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    </dbReference>
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            <end position="93"/>
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        <location>
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            <end position="462"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
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    </evidence>
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            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ADD41207.1"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
    <sequence length="619" mass="65658" checksum="C4C32D2FDBFCC80F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW64</accession>
    <name>D3PW64_STANL</name>
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        <recommendedName>
            <fullName evidence="9">Cytochrome c oxidase subunit 1</fullName>
            <ecNumber evidence="9">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
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        <name evidence="11" type="ordered locus">Snas_1517</name>
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        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
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            <dbReference type="DOI" id="10.4056/sigs.47643"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
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    </reference>
    <comment type="function">
        <text evidence="6 9">Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
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            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
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            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
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        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Energy metabolism; oxidative phosphorylation.</text>
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        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the heme-copper respiratory oxidase family.</text>
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        <property type="entry name" value="Cyt_c_oxidase_su1_bac"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CYCOXIDASEI"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="9" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0679">Respiratory chain</keyword>
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    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
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            <end position="148"/>
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            <end position="231"/>
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    </feature>
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        <location>
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            <end position="275"/>
        </location>
    </feature>
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        <location>
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            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
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        </location>
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    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="469"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="10">
        <location>
            <begin position="18"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD41221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="572" mass="63682" checksum="8B13FA95C4B2DC83" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWF7</accession>
    <name>D3PWF7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chitin-binding domain 3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1611</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1611"/>
    <dbReference type="CAZy" id="AA10">
        <property type="family name" value="Auxiliary Activities 10"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41314">
        <property type="protein sequence ID" value="ADD41314"/>
        <property type="gene ID" value="Snas_1611"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1611"/>
    <dbReference type="eggNOG" id="COG3397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047929_2_0_11"/>
    <dbReference type="OMA" id="FRWQFTA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048646" evidence="2">
        <location>
            <begin position="34"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-4" evidence="3">
        <location>
            <begin position="34"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="201" mass="20892" checksum="FD57B27C1ADFF94C" modified="2010-04-20" version="1">MPAPRTVRVGISVLAGTAAAVMLSVLGASPASAHGYTTSPTSRAAFCADGTVTDCGQIQWEPQSVEGPKGFPAAGPQDGSICAGGNGQFAELDDPRGGQWPATDVQPGGSMNFQWKLTAAHSTTDFQYFITKDGWDSSKPLTRADLDATPFLTVPFSGQPPSDVSHSGTLPNKSGKHLILGVWTIADTANAFYQCSDVNFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWI5</accession>
    <name>D3PWI5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MDMPI_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018778.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3545"/>
    <dbReference type="EnsemblBacteria" id="ADD43207">
        <property type="protein sequence ID" value="ADD43207"/>
        <property type="gene ID" value="Snas_3545"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3545"/>
    <dbReference type="eggNOG" id="COG1576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051661_2_1_11"/>
    <dbReference type="OMA" id="VTHTWDL"/>
    <dbReference type="OrthoDB" id="2055578at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017520">
        <property type="entry name" value="CHP03086"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03086">
        <property type="entry name" value="TIGR03086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="1">
        <location>
            <begin position="17"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="197" mass="21427" checksum="9A1AE005C0281A31" modified="2010-04-20" version="1">MTGITPTDTSFDPRPRLATALDQMQAQIEAVGADDLDRPTPCGDYNVRMLLGHVLAVIRKLAVAGRGGDASQVTDPADDITEGWTDAIRQARADLDQVWSADTSLERDCTLPWATMPGRDVLDTYTHEFTVHAWDLARATGRVDDLDPVLAKMALEWFSRNVPEDARSEDGAFGPAIAVADDADVFTKLAAYVGRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWP1</accession>
    <name>D3PWP1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lanthionine synthetase C family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3603</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018834.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3603"/>
    <dbReference type="EnsemblBacteria" id="ADD43263">
        <property type="protein sequence ID" value="ADD43263"/>
        <property type="gene ID" value="Snas_3603"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3603"/>
    <dbReference type="eggNOG" id="COG4403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049438_0_1_11"/>
    <dbReference type="OMA" id="CHGWAGA"/>
    <dbReference type="OrthoDB" id="393144at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd04793">
        <property type="entry name" value="LanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033889">
        <property type="entry name" value="LanC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="409" mass="42679" checksum="973CB007272584DE" modified="2010-04-20" version="1">MTTLDDQITTVAQRLRDPETVVAAVAGAEVASLTHGLAGTALLHARLAHIDPDFAHAAHRHWTAAAELLKNHPGGFSGIQGGLGGLAASLIIGTSYLPDTHHHPATAPGATWLSTCASDMADLYQRTDILTWDVYDAITGLAGIGRVLLAAHHTAVGNVEPGLKAALTTLTAILAPRDTHRPGWWMPAADHPEAVAVHPSGAATTGLAHGVAGPLAFLSTAHIAGWSVPGQTDAIDHAATWLVRWRRDDGTWPPAVTGDELDNHTPPATTGRADAWCYGTPGITRALILAGHALGEPEVLLIAGNALHDFADRSPEQWDVDGPTLCHGYAGIVQSQPAKDPVTKAAVNEVAAAFDPESPFGFQHHDHGQTHDQPGLLVGAAGVALALADYRQLPAPSTPAPWDCLLHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWS6</accession>
    <name>D3PWS6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018869.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3640"/>
    <dbReference type="EnsemblBacteria" id="ADD43298">
        <property type="protein sequence ID" value="ADD43298"/>
        <property type="gene ID" value="Snas_3640"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3640"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="WTEPRPP"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="180"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="380" mass="40146" checksum="F3476CC3A00483FA" modified="2010-04-20" version="1">MAANALRSLWVEPRPANAPPRGPRDWALVAVLICSTVLEAVLREDMAPLPLLFIAALAVVVPLPWRRTHPLVVTAVAFGTVTVVDTVRVLTESPGTLPSSVAATLVIAYALFRWGSGREAAGGLGIILVWLAITCVAESTNVVELVAGYAFFLFAAALGAAIRYRAKVRVRDLDQARARERELLARELHDTVAHHVSGIAIQAQAGRAIAASRPERAAEALAIIEDAATRTLTELRAIVGVLRAPPDTGFAPQPGVAEVEQLATDGHTRPRVAVTLSGEFDDLSPAVGAAIYRLAQESITNARRHARHATQVTVAVTGDADRVRLTIDDDGSAAGGRAPAGYGLVGMRERACLLGGTFHAGPTAERGWRVEAVLPRTGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWT2</accession>
    <name>D3PWT2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3646</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018875.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3646"/>
    <dbReference type="EnsemblBacteria" id="ADD43304">
        <property type="protein sequence ID" value="ADD43304"/>
        <property type="gene ID" value="Snas_3646"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3646"/>
    <dbReference type="eggNOG" id="COG3413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1174848_0_0_11"/>
    <dbReference type="OMA" id="FANELWW"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="236" mass="26165" checksum="4FB8D5B31D868CB4" modified="2010-04-20" version="1">MSGIDIEHDGATHRLEPGGSLTVGRDESCDICLDPQDMGISRLAGRIADVGGIWAVTNLSRKRPLHIVDATGFAVPLPVALSNGPPSRRVVDTVPMTVLIAGEEWTHALVLRLCHSPGEPAAPSPRDGLETRTQLPNMTDRRREVLVAMAEGYLRPYPFYDPRPRTYQDIADRLGLSKSQVVKRIEQVRLDLVAAGVLGLEKEVDARRALCEWLLATRALSRSDVDWLRHRRDRNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX36</accession>
    <name>D3PX36_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020831.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5630"/>
    <dbReference type="EnsemblBacteria" id="ADD45260">
        <property type="protein sequence ID" value="ADD45260"/>
        <property type="gene ID" value="Snas_5630"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5630"/>
    <dbReference type="HOGENOM" id="CLU_128232_2_0_11"/>
    <dbReference type="OMA" id="PIHNDIT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="122" mass="12747" checksum="090B0D232DB78C45" modified="2010-04-20" version="1">MPDPIMMAIAGAVAGKTAEVAFKGGRKAYDAVVALVKRRFAKEPLAQTALEAAESDPEANTERLAAALELVAAADPEFDRELRQAGQALIAAAPGATVNINSGTVGHDSYQAQTININRDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXH4</accession>
    <name>D3PXH4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1739"/>
    <dbReference type="EnsemblBacteria" id="ADD41437">
        <property type="protein sequence ID" value="ADD41437"/>
        <property type="gene ID" value="Snas_1739"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1739"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="VTAHIPY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="186"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="392" mass="41265" checksum="4C0FF9D394D954F6" modified="2010-04-20" version="1">MRNPPDDDDGPAPLFSRRLSRGQLIALDCVAAVGYVLALLPFSSRTGAPSWTVLLFAAATGLPVALRRLWPVPVFAVVLSASVTSLFFDVPRDSFVAAGFALYLVALTVRFDHRWLTSFIGVATIVFGLVLSVAGTVSAPYEAVASGLLGCVALGIAWTLGRAIRDRRAQADKAARRLAAELVSQERLHIARELHDVVAHSMSLIAVKAAVANHVAAKHPDEAHKALTVIETTAKTALTEMRRLLGVLRSESEEAAELAPAPGLSELPALARRAALAGVRVDIRADATVSDLPTGLDLSAYRIVQEAVTNVVKHAAPANCHVDVSHVDDQLRIRVTDDGPGGRVLPGDTAGHGLVGMAERVAMYGGEFDAAPRPGGGFAVSAKIPYPAEVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXJ1</accession>
    <name>D3PXJ1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3663</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3663"/>
    <dbReference type="EnsemblBacteria" id="ADD43321">
        <property type="protein sequence ID" value="ADD43321"/>
        <property type="gene ID" value="Snas_3663"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3663"/>
    <dbReference type="eggNOG" id="COG1510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120349_2_1_11"/>
    <dbReference type="OMA" id="LICDPPY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="152" mass="17169" checksum="B24CE4693AF91A26" modified="2010-04-20" version="1">MNDHIEHERLMEWVERLTAFLARDGVSPIAARCLGWLMVCDPPEQSAQQIGDAINASRGSMTTNLRLLTAMGFVTHRTRPGDRTTYYRVDDNAWDTVVRRQIASLTAFQDLAQNGLDILGPGTQRAARIKEAHDTFAWMSEVFNNAPPRRQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXS7</accession>
    <name>D3PXS7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018978.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3750"/>
    <dbReference type="EnsemblBacteria" id="ADD43407">
        <property type="protein sequence ID" value="ADD43407"/>
        <property type="gene ID" value="Snas_3750"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3750"/>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_11"/>
    <dbReference type="OMA" id="YRTNVLA"/>
    <dbReference type="OrthoDB" id="1135906at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="234" mass="24124" checksum="A46541C1BB21CD73" modified="2010-04-20" version="1">MTNNNPKIALITGASRGLGKALATELSRRGWRLLLTARGAEDLAAVASELDAEAIAGDVADPGHRERLAAAIERLGGLDLLVNNASSLGTSPLPRLADYSREVLTGLFDTNVVAPLALIQDLLPRLRERDGAVVNISSDAATGGYEGWGGYGATKAALDQVSNVLAAEEPGLRVWWVDPGEMRTAMLADAVGDEAADAPPPEAVAAPAIAGLLDSRPASGRYVAAELGVEAGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXV7</accession>
    <name>D3PXV7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5656"/>
    <dbReference type="EnsemblBacteria" id="ADD45286">
        <property type="protein sequence ID" value="ADD45286"/>
        <property type="gene ID" value="Snas_5656"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5656"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_414416_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="621"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="662" mass="70636" checksum="99A766D9A4D1FC62" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY06</accession>
    <name>D3PY06_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative DNA topology modulation protein FlaR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020906.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5705"/>
    <dbReference type="EnsemblBacteria" id="ADD45335">
        <property type="protein sequence ID" value="ADD45335"/>
        <property type="gene ID" value="Snas_5705"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5705"/>
    <dbReference type="eggNOG" id="COG0563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092618_0_0_11"/>
    <dbReference type="OMA" id="WIWEYPN"/>
    <dbReference type="OrthoDB" id="1793376at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="163" mass="18857" checksum="140AEE984026DF31" modified="2010-04-20" version="1">MVVGCAGAGKSTITVALNRAHGLPIVHLDRLYWKPGWQRSPDDEWELVLRELVAEDAWIHDGNYDSTMDFRLPRADLVVFVDTPRRRCLYRAVKRRLVGNRIHDIPGCPENLDREFFGYVWRFPTVHRPRLLERLAGHPNVVRLRTRREVRRFLAGLAAPSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY59</accession>
    <name>D3PY59_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase domain protein TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020959.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5758"/>
    <dbReference type="EnsemblBacteria" id="ADD45388">
        <property type="protein sequence ID" value="ADD45388"/>
        <property type="gene ID" value="Snas_5758"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5758"/>
    <dbReference type="eggNOG" id="COG1082">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065571_0_0_11"/>
    <dbReference type="OMA" id="EVMVWTD"/>
    <dbReference type="OrthoDB" id="1007505at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="24"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="263" mass="28926" checksum="941ACCBD0046905C" modified="2010-04-20" version="1">MAGASPPVLLSTSSVYPEPTAVAFELAAKLGYDGVEVMVWTDSVSQDFRTLATLSDHYGVKVGSVHAPCLLMTQRVWSKDPWERLRRAAVMAEHLEASTVVIHPPFAWQRGYGRVFPAGLERMAQRFPQLRFAVENMYPIKMARKGFVPYAPHWDPTNPGYDNYTLDLSHCAASNSDALEMAERMGSNLTHVHLGDGAGPGRDEHAVPGRGNQPCAELLRKLATSGNDFTVAVEVSTRKSGHRAVREADLAESLNFARRHLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYA6</accession>
    <name>D3PYA6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M16 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1776</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017044.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1776"/>
    <dbReference type="EnsemblBacteria" id="ADD41473">
        <property type="protein sequence ID" value="ADD41473"/>
        <property type="gene ID" value="Snas_1776"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1776"/>
    <dbReference type="eggNOG" id="COG0612">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009902_6_1_11"/>
    <dbReference type="OMA" id="RLMRYEY"/>
    <dbReference type="OrthoDB" id="1077305at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="1">
        <location>
            <begin position="65"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="2">
        <location>
            <begin position="178"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="438" mass="46511" checksum="258035C886B55BD9" modified="2010-04-20" version="1">MTVHTVPDLAPATEFTLPDCHERVLDNGLTILAIRRPSVPLVEVRLRLPFAEADVAVSSVMAQTIMSGTADKSIVDIAAELQSVGGGLSASVDPDRFLLAGNALVDGLPRLLATMSEVLHGATYPEDQVDVERERLADHINVARQQPGHLVQVALLKRMYGAHPYAVQTPEPEDVGAITPQQLLDLHAGRIHPAGATLVIVGDLPAEQALDAGAAALADWNGHSEPRSLEPVAPLTAGPVTFVDRPDSVQSSIRVALTALPRVHDDNAAQQLANLIYGGYFSSRLVANVRENKGYSYSPRSAVDHALAGSAVVISADVATEVTAPALWEVWYELGRIAATPPTEDELEQARRYALGTLRLGTATQSGLASLASSFAGWDLRPDWLLEHANRLASVTIEDVQRVAADIFAPAKAVTVVLGDAAHVKAPLEGLTHVEGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYC9</accession>
    <name>D3PYC9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017067.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1800"/>
    <dbReference type="EnsemblBacteria" id="ADD41496">
        <property type="protein sequence ID" value="ADD41496"/>
        <property type="gene ID" value="Snas_1800"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1800"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="ICGKTKA"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="312" mass="34285" checksum="94C706007A89D77F" modified="2010-04-20" version="1">MSTAPHISAHKLVKRYGDSNAVDGIDLSVAPGEAFGFLGPNGAGKSTTMRMIGCVSRPTGGQLSVLGMDTATQGPAIRARLGVVPQEDTLDTEITLFDNLVIYARYFGIKYKVAKQRATELLEFVRLADRAKMKVEELSGGMKRRLTIARALVNEPDIIMLDEPTTGLDPQARHLVWERLFRLKQRGITIILTTHYMDEAEQLCDRLVIMDGGRIAAQGSPRELIDTHVTREVVELRFEGQHTDELSDLADKLDGIDAQVEALPDRILLYAADGDAAVAEVHGRAIQPSSVLARRATLEDVFLRLTGRSLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYH5</accession>
    <name>D3PYH5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1846</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017113.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1846"/>
    <dbReference type="EnsemblBacteria" id="ADD41542">
        <property type="protein sequence ID" value="ADD41542"/>
        <property type="gene ID" value="Snas_1846"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1846"/>
    <dbReference type="eggNOG" id="ENOG502ZY4N">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037015_0_1_11"/>
    <dbReference type="OMA" id="HLVWYLP"/>
    <dbReference type="OrthoDB" id="1939201at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="440" mass="46945" checksum="ACFE48F23693BFF9" modified="2010-04-20" version="1">MTAVVDTEVRQPQPEAPRKRPPLRRRHLLIPLAAAAALIVFTIVAAFVESPSPGSDSFLSPRAAGGNGSSQLAKSLEEKDVTVDRFTDAGDSFFDAASSGDTTVFIPAPDYLNSSEISRLQEAAIAENTRVVFVDPSRDLLGSLGLSEAGAPRIAPKVVAPSDGCDLPEAAKAGDAGMLRQAYAEAKSSGGLELDLNWRFCYDDGLAWTGTGSMSFVVAGAADPFTDEYFGEAGNAELATGLLGQHRKVVWLDKHSLTKEPPPSETLPTPDGDYTPPPDPSRDPIEYPNQGQTNPIYDAMPAWMWAMLLGALVLGVLMALWKGRRLGPPVTEPLPVTVPAAETVHGRARLYRRAHAYTETLRALRAGALHRIRPVLGLSSQAGDAEVVEAVATRTGWPREHITATLYSTQPTNEDELYNATQAIDALVSAVENASPQGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYS5</accession>
    <name>D3PYS5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3852</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019079.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3852"/>
    <dbReference type="EnsemblBacteria" id="ADD43508">
        <property type="protein sequence ID" value="ADD43508"/>
        <property type="gene ID" value="Snas_3852"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3852"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="WRREHAY"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="21"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="103"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="170" mass="19915" checksum="5B21334991F16C64" modified="2010-04-20" version="1">MRPEHESEYCDYAANRLVPMRRFAYLVCGDWHRAEDAVQNAFVKLYLAWARAQRADSLDAYTRRIVLNCVKEVQRRHWFTRERSTSEPPDRAATGDTGSEERRLVLDALAQLPMRRRATLVLRYWEDLSVEQTARVLRCSPATVKSQTVRGLRTLRGLLTDSFREQIERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYT3</accession>
    <name>D3PYT3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019087.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3860"/>
    <dbReference type="EnsemblBacteria" id="ADD43516">
        <property type="protein sequence ID" value="ADD43516"/>
        <property type="gene ID" value="Snas_3860"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3860"/>
    <dbReference type="eggNOG" id="ENOG502Z9Y5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_547202_0_0_11"/>
    <dbReference type="OMA" id="FSWPDGL"/>
    <dbReference type="OrthoDB" id="1834774at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="424"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="443" mass="46496" checksum="8E275D7718561B3F" modified="2010-04-20" version="1">MAGLQTRNRVQASGVGNRERLDATVWMVLVAAGLLITVLAVALGAQLGTDAPPFLLGYQLEASPGLVAPLLVIVGVLWTVRRRFAVRCHWPSLLALSYVGAFAWLVALSLPHGADGLTRYVRDADGYTPPVNAGSISEILTSLAQPDGHASTAVTGHPPGPAVLLWLLRWLPLSDTAIALVWTALAAATVPLVLLAARSTCGPVAARRMAPLLVLAPYGLWMAVGPDAITAMLGAGALAAACHASHRRCRGWSATGWALLAGVLLAAATMFAYVAAWLGLSMVCLYFARRRPWHNLATGAVTLVPLAWLQAAGFDWVTGLTDAYHGFLGRVEEGRSLWWWIPLSLTVLIIACGPAIVASARKFRNTPAWPFLVGACAAIVFSVVAGIARGGVEQTWLVFFPWLTIAATAPAVQAGRPLPVPARLAALGGLGAVALAAVLISPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYW2</accession>
    <name>D3PYW2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_3890</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.35" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019116.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3890"/>
    <dbReference type="EnsemblBacteria" id="ADD43545">
        <property type="protein sequence ID" value="ADD43545"/>
        <property type="gene ID" value="Snas_3890"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3890"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_15_3_11"/>
    <dbReference type="OMA" id="IIDIWAR"/>
    <dbReference type="OrthoDB" id="977512at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="9">
        <location>
            <begin position="316"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="8">
        <location>
            <begin position="497"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="711" mass="75101" checksum="B8D366BA58ADB280" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYX6</accession>
    <name>D3PYX6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formiminoglutamate deiminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020976.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5775"/>
    <dbReference type="EnsemblBacteria" id="ADD45405">
        <property type="protein sequence ID" value="ADD45405"/>
        <property type="gene ID" value="Snas_5775"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5775"/>
    <dbReference type="eggNOG" id="COG0402">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012358_3_1_11"/>
    <dbReference type="OMA" id="MCPTTER"/>
    <dbReference type="OrthoDB" id="1592010at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010252">
        <property type="entry name" value="HutF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43608">
        <property type="entry name" value="PTHR43608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02022">
        <property type="entry name" value="hutF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="55"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="453" mass="47669" checksum="32BBF0C88E08D717" modified="2010-04-20" version="1">MTGYLPQRSYFAERAWLSSTDGLVENVRIDVVAGMIESVVVGEAAPADAVRLPGFVMPGLVNAHSHAFHRALRGRTHGGGGDFWTWREQMYTVARRLDPDSYRALARAVYAEMALAGITTVCEFHYVHHGPDGVPYEDPAAMPQALAQAARETGMFLVYLDTCYLQSDVSGTPLSGPQRRFGDAGIEAWLERVEAVKLARPGPDALGVAIHSVRGCPPEAMRAVARWAREHDAPLHIHLSEQVKENEDCVAVHGLTPAGLCAETGVLGPETTAVHATHLTEADIRLLGDSGTIAGFCPTTERDLADGIGPAAALRAAGSPLSLGSDSHAVIDLFEEARAVELNERLATQRRGIHGAPALLAAATEGGAASAGLSRRAGRIAEGHYADFVAVDTSSVRLAGADDPVAAVVFAASACDVTHVVSGGEVIVEDGRHTMVDDVAGELASVVSALFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ18</accession>
    <name>D3PZ18_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5817</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021018.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5817"/>
    <dbReference type="EnsemblBacteria" id="ADD45447">
        <property type="protein sequence ID" value="ADD45447"/>
        <property type="gene ID" value="Snas_5817"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5817"/>
    <dbReference type="eggNOG" id="COG4805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028527_0_0_11"/>
    <dbReference type="OMA" id="VHEAMPG"/>
    <dbReference type="OrthoDB" id="520320at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="536" mass="59222" checksum="57BFD1FD8504F129" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ83</accession>
    <name>D3PZ83_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltranfer_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021083.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5884"/>
    <dbReference type="EnsemblBacteria" id="ADD45512">
        <property type="protein sequence ID" value="ADD45512"/>
        <property type="gene ID" value="Snas_5884"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5884"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031012_0_0_11"/>
    <dbReference type="OMA" id="CGYETKV"/>
    <dbReference type="OrthoDB" id="880894at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13679">
        <property type="entry name" value="Methyltransf_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="2">
        <location>
            <begin position="147"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="376" mass="41125" checksum="BF5BFBAA7CA05F7D" modified="2010-04-20" version="1">MTESLEQALAEIRGLLAERHKLVRAVASGRRRNERPAHVKTELRPVAVKGGVKLQISQHDGQRPLVTNVDGDEADKRVDDVLAEPYGNWLVETTEATVQLRVTKRGDAQVHRAAASRDRDLAHDRTPPHLIAPDDPLFRELGAGAAKRRQVDAFLRAVASLLGDGAAVEHVVDLGCGNAYLTFATHRYLNLAGADPRVTGVDVREDQRHRNTELAQKLGVGERVRFIAGTAAETPLDDVDMVLALHACDTATDDALARGVSLGAKHIVAAPCCHHDLAAQLRKAAAPSPYGQLTADGILRERFADVLTDALRATLLRAHGYRVDVIEFIDSAHTPRNTLLRATRSTATPDPRHAEEFRQLTSQWNIRPYLADLLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ86</accession>
    <name>D3PZ86_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021086.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5887"/>
    <dbReference type="EnsemblBacteria" id="ADD45515">
        <property type="protein sequence ID" value="ADD45515"/>
        <property type="gene ID" value="Snas_5887"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5887"/>
    <dbReference type="eggNOG" id="ENOG5032RVX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117498_0_0_11"/>
    <dbReference type="OMA" id="PRPMRFF"/>
    <dbReference type="OrthoDB" id="1775135at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045713">
        <property type="entry name" value="DUF6069"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19545">
        <property type="entry name" value="DUF6069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="177" mass="18386" checksum="1E6A28CF3D770E9B" modified="2010-04-20" version="1">MSEPNYRYGQASPRQPVDPTQRMPSASAPEPKPQPRINAGKLWAGGVGAAVVVALVVLVGILLVRGVLKIPVLAAQGEGAYGTASTTTYAVTAGALALAATALLHVLLIAMPRPMQFFYWICALVTAVAVLLPFTLVAELNAQVATAGINLVAGICLMSVLGSIGASSVNYDREPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZE7</accession>
    <name>D3PZE7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017192.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1925"/>
    <dbReference type="EnsemblBacteria" id="ADD41621">
        <property type="protein sequence ID" value="ADD41621"/>
        <property type="gene ID" value="Snas_1925"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1925"/>
    <dbReference type="eggNOG" id="COG3118">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046120_0_0_11"/>
    <dbReference type="OMA" id="QPRNMSM"/>
    <dbReference type="OrthoDB" id="1630944at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="23"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="299" mass="31634" checksum="CE00CBAC4097A80D" modified="2010-04-20" version="1">MNTPEPSQAPQRLLAGAVDLSSLAAPRPAPPRPTDGEAPAAANGAAVIDVTEATFQAEVLERSLSVPVVIDFWADWCQPCKQLSPVLEKLAVESGGAWTLAKIDVDANPQLQAAFQVQSIPMVIAMWQGRPVDGFQGVQPETTLRQWIGRLIEATGGEAPEVPADPQLVAAESALDAGDLTGAENAFTSYLDLHPGDAAAESGLAQVRLLRRVEAAGPAAQEAAVTNPTDIPQALLASDIQVINGQAENAYRQLIDLIARLNGEDRDTVRKHLLDLFTIAGPEDPVVAQARRKLAAVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZQ0</accession>
    <name>D3PZQ0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3933"/>
    <dbReference type="EnsemblBacteria" id="ADD43587">
        <property type="protein sequence ID" value="ADD43587"/>
        <property type="gene ID" value="Snas_3933"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3933"/>
    <dbReference type="HOGENOM" id="CLU_3012114_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="56" mass="6389" checksum="CE2EBE956A468933" modified="2010-04-20" version="1">MKWTVTLRSAGGQEWTYEIETDPKTSQTEVARAAWLWHDREGGGEVDPRLTEANRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZS9</accession>
    <name>D3PZS9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3964</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019187.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3964"/>
    <dbReference type="EnsemblBacteria" id="ADD43616">
        <property type="protein sequence ID" value="ADD43616"/>
        <property type="gene ID" value="Snas_3964"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3964"/>
    <dbReference type="HOGENOM" id="CLU_2652706_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048503" evidence="2">
        <location>
            <begin position="28"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="76" mass="7807" checksum="7B0BE832BB803D80" modified="2010-04-20" version="1">MRKEPLITVATITALASAVLSALVAFGINLTEAQSTSILGLVAVAAPLAVAWFARSKVASPNTVEKIQAEQTANAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZU7</accession>
    <name>D3PZU7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease V</fullName>
            <ecNumber evidence="1">3.1.21.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Deoxyinosine 3'endonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Deoxyribonuclease V</fullName>
            <shortName evidence="1">DNase V</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nfi</name>
        <name evidence="2" type="ordered locus">Snas_3982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate.</text>
            <dbReference type="EC" id="3.1.21.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the endonuclease V family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.7" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019205.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3982"/>
    <dbReference type="EnsemblBacteria" id="ADD43634">
        <property type="protein sequence ID" value="ADD43634"/>
        <property type="gene ID" value="Snas_3982"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3982"/>
    <dbReference type="eggNOG" id="COG1515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047631_1_1_11"/>
    <dbReference type="OMA" id="RIHFRQA"/>
    <dbReference type="OrthoDB" id="1681607at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043737">
        <property type="term" value="F:deoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06559">
        <property type="entry name" value="Endonuclease_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00801">
        <property type="entry name" value="Endonuclease_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007581">
        <property type="entry name" value="Endonuclease-V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28511">
        <property type="entry name" value="PTHR28511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04493">
        <property type="entry name" value="Endonuclease_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with target DNA" evidence="1">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="223" mass="23869" checksum="058EA9F743186508" modified="2010-04-20" version="1">MTKYPWPTDVETAEKLQESLRTRVCREGVRVAPGVVAGVDIAYDKDSELAAAAAVAFELGSLAVVATATVVGRVEFPYRPGLLGFREVPLSSQVLERLDVAAELVVCDGHGLAHPRGFGMACHLGVHMNQPTMGIAKNPPEFAVNEPGKRRGSSTLIFNGDDVVGACLRTQDNVKPVYVSVGHRIGLDEAVEVALRLSPRFRLPATTRAADRLSRDTLAEALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZV8</accession>
    <name>D3PZV8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Imidazole glycerol phosphate synthase subunit HisH</fullName>
            <ecNumber evidence="8">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IGP synthase glutaminase subunit</fullName>
            <ecNumber evidence="8">3.5.1.2</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">IGP synthase subunit HisH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">ImGP synthase subunit HisH</fullName>
            <shortName evidence="8">IGPS subunit HisH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisH</name>
        <name evidence="11" type="ordered locus">Snas_3993</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="8"/>
    <dbReference type="EC" id="3.5.1.2" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019216.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3993"/>
    <dbReference type="EnsemblBacteria" id="ADD43645">
        <property type="protein sequence ID" value="ADD43645"/>
        <property type="gene ID" value="Snas_3993"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3993"/>
    <dbReference type="eggNOG" id="COG0118">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071837_1_0_11"/>
    <dbReference type="OMA" id="WVYFVHS"/>
    <dbReference type="OrthoDB" id="1726024at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42701">
        <property type="entry name" value="PTHR42701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000495">
        <property type="entry name" value="Amidotransf_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="7"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 9">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000495-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD43645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="202" mass="20962" checksum="02A3297C925D00F2" modified="2010-04-20" version="1">MKPSVVVFDYGSGNLRSAARALEHAGADVTVTADTAAAVRAHGLVVPGVGAFASCMDGIRSCGGDKVIAERRAAATPVLGICVGAQILFDAGTEHGTRTTGLGVFDGEVTALRAERVPHMGWNTVDQTGMPLFEGLAPDARFYFVHSYAVHGTIPGAQVATCDYGDPFVAAISRDTVSATQFHPEKSGSAGLTLLSNWVRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q020</accession>
    <name>D3Q020_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Myo-inositol-1-phosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5921</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the myo-inositol 1-phosphate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021120.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5921"/>
    <dbReference type="EnsemblBacteria" id="ADD45549">
        <property type="protein sequence ID" value="ADD45549"/>
        <property type="gene ID" value="Snas_5921"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5921"/>
    <dbReference type="eggNOG" id="COG1260">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050011_0_0_11"/>
    <dbReference type="OMA" id="GTKEWAD"/>
    <dbReference type="OrthoDB" id="669352at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004512">
        <property type="term" value="F:inositol-3-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002587">
        <property type="entry name" value="Myo-inos-1-P_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013021">
        <property type="entry name" value="Myo-inos-1-P_Synthase_GAPDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01658">
        <property type="entry name" value="Inos-1-P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015578">
        <property type="entry name" value="Myoinos-ppht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inos-1-P_synth" evidence="2">
        <location>
            <begin position="191"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="359" mass="39138" checksum="493F6B1C6F13FE01" modified="2010-04-20" version="1">MGTIRVAVVGVGNCASSLVQGVEYYRAADPSDRVPGLMHVQFGDYHVGDIEFVAAFDVDAKKVGRDLSEAMVASENNTIQFCEVPPTGVTVQRGPTLDGLGQYYNEIVDEADGEPVDVAQTLRDARAEVVICYLPVGSEEAARFYAQAAIDAGCAFVNALPVFIASRPDWAEKFTAAGLPIVGDDIKSQVGATIVHRALAKLFEDRGVELLRTYQLNFGGNMDFMNMLERSRLMSKKISKTQSVTSQVPHEMQGSDVHIGPSDHVPWLTDRKWAYIRLEGRSFGDTPLNAELKLEVWDSPNSAGVIIDALRAAKIALDRGVAGPVDSASAYFMKSPRKQYSDHDAHQAVEDFIAGRIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0F6</accession>
    <name>D3Q0F6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">Imidazolonepropionase</fullName>
            <ecNumber evidence="1 4">3.5.2.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Imidazolone-5-propionate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hutI</name>
        <name evidence="7" type="ordered locus">Snas_0099</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>4-imidazolone-5-propanoate + H2O = N-formimidoyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23660"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
            <dbReference type="EC" id="3.5.2.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc or iron ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-dependent hydrolases superfamily. HutI family.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.7" evidence="1 4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0099"/>
    <dbReference type="EnsemblBacteria" id="ADD39820">
        <property type="protein sequence ID" value="ADD39820"/>
        <property type="gene ID" value="Snas_0099"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0099"/>
    <dbReference type="eggNOG" id="COG1228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041647_1_0_11"/>
    <dbReference type="OMA" id="CAPHARW"/>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00551"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050480">
        <property type="term" value="F:imidazolonepropionase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00372">
        <property type="entry name" value="HutI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005920">
        <property type="entry name" value="HutI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42752">
        <property type="entry name" value="PTHR42752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01224">
        <property type="entry name" value="hutI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="6">
        <location>
            <begin position="54"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>N-formimidoyl-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>N-formimidoyl-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD39820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="469" mass="49866" checksum="1ED881167AD3E09F" modified="2010-04-20" version="1">MSLLVDNIGELSTCVGEPLSDAAVAIDGYEIAWVGPSGDAPSCDERVDAGGRAVIPGFVDSHSHLVFTGDRSAEFAARMAGRPYTAGGIRTTVAAVRGADDETLRANVRKHRAEMLRQGTTTVEIKSGYGLTVDDEARALRIASEFTSETTYLGGHIVPPEADADEYTALVAGDMLMSCLPYARWADVFCDRGAFDVEQAREILTAARDAGLGLRVHGNQLQHGPGVRLAVELGAASVDHCTFLSDADVEALADGDTVATLLPGVEFSTRSPFPDAKRLLDAGVTVALASDCNPGSCYSSSMPLMIAFAVRDMGMTVEQALWAATAGGARALRRDDLGVVAVGKRADLVILDAPSFVHLAYRPGVPLVHSVVHDGKIVDMALTRRLTFVRAASVARMGSKVWRYVSKPHQRPQVAAGKDSVDAVLDRVRLRSPRGVDSVGRRLRLHDQVRLDPGPGLRGPDRAVGRAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0L2</accession>
    <name>D3Q0L2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017319.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2054"/>
    <dbReference type="EnsemblBacteria" id="ADD41748">
        <property type="protein sequence ID" value="ADD41748"/>
        <property type="gene ID" value="Snas_2054"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2054"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085376_5_2_11"/>
    <dbReference type="OMA" id="ARESEPH"/>
    <dbReference type="OrthoDB" id="1069752at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="186" mass="19741" checksum="550AE6AD57925785" modified="2010-04-20" version="1">MGEGPRPLIEVIAHALRRERDRAGLSLSEVAKRAGIAKSTLSQLEAGSGNPGVETLWALSVALNVPFATLVEPSTSRVQVIRAGQGPTFAAEHADYVATVLSASPPRARRDLYLVTGQPGKARDSEPHMYGVVEHVIVCAGRALVGPIDEPVELTPGDYISYPGDAAHTFKALEPDTFAVLVSEHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0W6</accession>
    <name>D3Q0W6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate kinase FGGY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4064</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FGGY kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019287.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4064"/>
    <dbReference type="EnsemblBacteria" id="ADD43716">
        <property type="protein sequence ID" value="ADD43716"/>
        <property type="gene ID" value="Snas_4064"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4064"/>
    <dbReference type="eggNOG" id="COG1070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009281_3_0_11"/>
    <dbReference type="OMA" id="ELHAVDC"/>
    <dbReference type="OrthoDB" id="1619686at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="2">
        <location>
            <begin position="45"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="3">
        <location>
            <begin position="300"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="548" mass="57441" checksum="2346BDEEED4A32DA" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q124</accession>
    <name>D3Q124_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4123</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019345.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4123"/>
    <dbReference type="EnsemblBacteria" id="ADD43774">
        <property type="protein sequence ID" value="ADD43774"/>
        <property type="gene ID" value="Snas_4123"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4123"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1501861_0_0_11"/>
    <dbReference type="OMA" id="QPPGRGW"/>
    <dbReference type="OrthoDB" id="1846332at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="41"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="181" mass="20056" checksum="8BC228E390C21DA6" modified="2010-04-20" version="1">MPQPPQSSRKPASRWRASAYKVFYALPKVVRRRLVRIVAPTYTVGAVMMVYSPDRSQILLLRQPPGFGWGLPAGLLDRGERPEQAAIRELREETGIDLGLEAISPAAPSAVIHTRGRWVDTVFVTEVEPDSVELVIDGAEVWEAKWWPVTAMPPITVAASRLLAHYGLGPYADYPEAARVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q162</accession>
    <name>D3Q162_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6017"/>
    <dbReference type="EnsemblBacteria" id="ADD45642">
        <property type="protein sequence ID" value="ADD45642"/>
        <property type="gene ID" value="Snas_6017"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6017"/>
    <dbReference type="eggNOG" id="ENOG5030RUJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_590390_0_0_11"/>
    <dbReference type="OrthoDB" id="1992923at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="496" mass="50778" checksum="737EEE079681B438" modified="2010-04-20" version="1">MGAAQPPAAGGGYPPPPGDINLGVSGFGIEPPKKSRKGLVIGISAAVVLALGGGGAWAAASFFGTDGTDTETKLPASTAAFASFNLDVSKSQQLELLDLIEKFPESDVKSDDPEKAVAEFMKMLEDDDEDFAKGKFSEWVGLSTSIALWEHDGKPYALATVASTDDGKAKEGLTALQKDSGGEADMGFEVKDGTATMAFGEDKSQAAAKAAVKEAEKDPLSESDKFADAAEFLGEGQVVTAWADLEQAYKLGKESVPQSEYGGDPFSMMGDFEKNMKGQIAVGAKADDFGIEIVSSTFGAKDVTEGKEGLMDKLSKSPDADIAGAFALPDDFSESLGAAAGGLLTGGLTGAPGQDPNGETQAIFDALSGATGTFGMTGLTGAPQGQAVIETTSADKANTLKGLADSTGGEIEATVEGNTVTGKSSGYSPSGKLSGHKYYSDAVGGAPEAINYAMFMDVTKMMDEQDKKEMGALKAVGVAFGSKGGESVGNVRLIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1A8</accession>
    <name>D3Q1A8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_6064</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021259.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6064"/>
    <dbReference type="EnsemblBacteria" id="ADD45688">
        <property type="protein sequence ID" value="ADD45688"/>
        <property type="gene ID" value="Snas_6064"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6064"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_11"/>
    <dbReference type="OMA" id="FSEAPAW"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="49"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="360"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="575" mass="60673" checksum="1301089E3372B2BD" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1S7</accession>
    <name>D3Q1S7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0206</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015496.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0206"/>
    <dbReference type="CAZy" id="GH43">
        <property type="family name" value="Glycoside Hydrolase Family 43"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD39925">
        <property type="protein sequence ID" value="ADD39925"/>
        <property type="gene ID" value="Snas_0206"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0206"/>
    <dbReference type="eggNOG" id="COG3507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009397_4_0_11"/>
    <dbReference type="OMA" id="YLFFPAR"/>
    <dbReference type="OrthoDB" id="386120at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="3">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD39925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="304" mass="33041" checksum="7895227195C6AE61" modified="2010-04-20" version="1">MTFTNPVHDHNFPDPGALRVGDVYYVYGTNDGVHNVPLLISMDLVEWTLVGDALPELGRWAESGRTWAPEVLRTDSGYVMYYTARSPKDDLQCLGLAVSTSPGGPFVDTAERPFIAQTDEGGSIDASPFTDADGQVYLHWKNDGNHVGVATHLYGQRLSSDGRELLGEPVRLLTNREPWHGHVIEAPQMFLRDGQHYLFYSAGAFDSDGYAVGYARCDSPLGPVHDAPENPILTSGPGAAGPGHCSIVIGPDGDSTWMLYHAWPPDAIGSGVSARGRRLWLDRVEWRDGSPVVHGPTANPQPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1W6</accession>
    <name>D3Q1W6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017404.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2139"/>
    <dbReference type="EnsemblBacteria" id="ADD41833">
        <property type="protein sequence ID" value="ADD41833"/>
        <property type="gene ID" value="Snas_2139"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2139"/>
    <dbReference type="HOGENOM" id="CLU_148707_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="145" mass="16106" checksum="24FDC654E8DAC70E" modified="2010-04-20" version="1">MNDIPSDVTAVELNELWRVANIHFPKVENVYWEQIKAVHEVNGDPNDEKFGRCHPWWTAVACELERALFSSVGSLASAASALNRAVDAYAHVDGNSGKELTEVGKGLENIIKSEGSEPVDWTPPKDYQGPNFNQPDSWSEEHADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q202</accession>
    <name>D3Q202_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyrroloquinoline-quinone synthase</fullName>
            <ecNumber evidence="2">1.3.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Coenzyme PQQ synthesis protein C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Pyrroloquinoline quinone biosynthesis protein C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pqqC</name>
        <name evidence="4" type="ordered locus">Snas_2177</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = H(+) + 2 H2O + 2 H2O2 + pyrroloquinoline quinone</text>
            <dbReference type="Rhea" id="RHEA:10692"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58442"/>
            <dbReference type="ChEBI" id="CHEBI:58778"/>
            <dbReference type="EC" id="1.3.3.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PqqC family.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.11" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017440.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2177"/>
    <dbReference type="EnsemblBacteria" id="ADD41869">
        <property type="protein sequence ID" value="ADD41869"/>
        <property type="gene ID" value="Snas_2177"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2177"/>
    <dbReference type="eggNOG" id="COG5424">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080136_0_0_11"/>
    <dbReference type="OMA" id="AYVHFVR"/>
    <dbReference type="OrthoDB" id="1571811at2"/>
    <dbReference type="UniPathway" id="UPA00539"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033732">
        <property type="term" value="F:pyrroloquinoline-quinone synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018189">
        <property type="term" value="P:pyrroloquinoline quinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00654">
        <property type="entry name" value="PQQ_syn_PqqC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011845">
        <property type="entry name" value="PqqC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039068">
        <property type="entry name" value="PqqC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40279">
        <property type="entry name" value="PTHR40279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="SSF48613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02111">
        <property type="entry name" value="PQQ_syn_pqqC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 2" id="KW-0884">PQQ biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TENA_THI-4" evidence="3">
        <location>
            <begin position="14"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="230" mass="26171" checksum="10B39DAF6B9FC581" modified="2010-04-20" version="1">MHGDTLDADEFTAELRGLSNRYWGSHPFHIRLHSGELSKDELRLWAANRWYYQSILPQKDAAIIANCPDREVRRLWVDRIVYHDGRPGDEGGADRWLRLCEAIGLDRGEVVDLRHLLPGVRFAVDAYLNFARNRPWLEAVASGLTEMFSGHLMRRRVDDMLAAYPWIRPADLEYFSNRIGAVSDEGATALDIVVRHSLTREQQRAAVSALSFKCDVLWSMLDAIAAGARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q220</accession>
    <name>D3Q220_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2195"/>
    <dbReference type="EnsemblBacteria" id="ADD41887">
        <property type="protein sequence ID" value="ADD41887"/>
        <property type="gene ID" value="Snas_2195"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2195"/>
    <dbReference type="eggNOG" id="COG0520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_3_1_11"/>
    <dbReference type="OMA" id="TGNCHKW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="1">
        <location>
            <begin position="62"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="390" mass="42096" checksum="676E70AFBE15B1A3" modified="2010-04-20" version="1">MPQSTPPEPFPAARALFTLDPDLTHLNHGSLGAVPLPVRRAHTRITDELEADPRGFFKTRVERVTATRNRLAEFVGADPRRTALVTNIVTGVSQVLQALELKAGDEIVTTDHGYGAVGYNVDAYGRHTGVVHKVAAVPLTPTADELVTAIVDQLSPRTRLVICDHITSATARLFPVAKLAAALREHDVPLLVDAAHVPGHVDADIDGIGADFWIGNLHKWSFAPRGTALLSVAEHWVGRMRPLMESWQHEAGFPVATEYNGTDDFTGWLAAPAGVALLTELGMERVRRHNSQLAHYGQTVLAQALGTTVPDDEPSPMAMRLVPLPDGVGTTDAASDAIEEAVRDELRTELTVNTFGGQGVMRVAAQIYNTPADYETLAERLPGLLKRLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2B8</accession>
    <name>D3Q2B8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019422.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4201"/>
    <dbReference type="EnsemblBacteria" id="ADD43851">
        <property type="protein sequence ID" value="ADD43851"/>
        <property type="gene ID" value="Snas_4201"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4201"/>
    <dbReference type="HOGENOM" id="CLU_2791967_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="68" mass="7275" checksum="B8201C8AFB4E1D9B" modified="2010-04-20" version="1">MTEPGGRDESYIPLPCPGCAGKGVNYMPHMAIGPLRGHLRSGQVATLLAAGRCEECLGNGRLRRPKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2I7</accession>
    <name>D3Q2I7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Low temperature requirement A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019491.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4271"/>
    <dbReference type="EnsemblBacteria" id="ADD43920">
        <property type="protein sequence ID" value="ADD43920"/>
        <property type="gene ID" value="Snas_4271"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4271"/>
    <dbReference type="eggNOG" id="COG4292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045667_2_1_11"/>
    <dbReference type="OMA" id="HWAERHA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010640">
        <property type="entry name" value="Low_temperature_requirement_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36840">
        <property type="entry name" value="PTHR36840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06772">
        <property type="entry name" value="LtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="387" mass="41591" checksum="111E19731FD51278" modified="2010-04-20" version="1">MNLPLPRWYREKVEPVPDTEDQKVSTLELFFDLVFVFTVTQLTHVVAHDFTSGVIQTLLMFAVIWYMYSAYAWMTNAVPPQRPARRVLLLVAMAGWFVIALAVPDAFHGTGVWLGAGMVVVVVLHGLMYLQSTNRILVFLSVNLTGAILIVIAGFQHGLPQYLLWTAALVVMWLGPALTGQEGFPLHPGHITERHGLVVIVALGESIIVVGSGALKVGEKTGELNGQIISVAILGLALTACLWWAYFTADAVRAEHALVSTGDQVRRTRMVLLGFFFSHIPILLGIVGMAAGLGDAIGKATKPLAGGPGIALGAGVALFLLGSVLFRISLRLPAGTVRIVAVVLSLATIPLGRVAAVWQLVALFGILLAVVITEEASRRRDQLVTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2R2</accession>
    <name>D3Q2R2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FBP_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021384.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6190"/>
    <dbReference type="EnsemblBacteria" id="ADD45813">
        <property type="protein sequence ID" value="ADD45813"/>
        <property type="gene ID" value="Snas_6190"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6190"/>
    <dbReference type="eggNOG" id="ENOG5031HHY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116295_0_0_11"/>
    <dbReference type="OMA" id="WRDPQAP"/>
    <dbReference type="OrthoDB" id="1684141at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032330">
        <property type="entry name" value="EF-G-binding_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16571">
        <property type="entry name" value="FBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FBP_C" evidence="1">
        <location>
            <begin position="8"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="166" mass="18234" checksum="438D8354E8D5079E" modified="2010-04-20" version="1">MKALTDTELRTGFANCSKGEASSIALPDLNAVNWENLDFLAWRNPRMPQRAYLAVVTDDKPVSLVLRAAERRSTSGAMRSSMCEFCQTVHSAGGVTLFTAKKAGSSGRRGDSVGTYICSTLDCCLYVRNLKRPARVQPESTLTVDERIDRLNYKVNGIVQRVLEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3B2</accession>
    <name>D3Q3B2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2264</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017524.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2264"/>
    <dbReference type="EnsemblBacteria" id="ADD41953">
        <property type="protein sequence ID" value="ADD41953"/>
        <property type="gene ID" value="Snas_2264"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2264"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_0_11"/>
    <dbReference type="OMA" id="KTFDIVW"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="209"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="79"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="301" mass="32545" checksum="CF4F39CE95867B1A" modified="2010-04-20" version="1">MTSEKTPTAKSARRRDPYRRSAAGFIAPGVLLVAVLLYLPLLWTTFLSFTEYNGLGDPEWIAFDNYVEMFDDPEFLGSVFNTLLWVLGTLLVPVGIGLGIALLTWNLKGGSWLRLPFLIPYALSGIGVGVIWSFVLSGDGALDQALAAFGVTDTPRWLVDAPLNTVVMILATAWQGVGVNALLFTIGLQSIPKEPLEAARMDGANGFRLFRSILWPMLRPLTAVVVGLSIVASLKTFDIVQGMTKGGPGRDSETLALTMYKESFVNTEYGLGAAIAVFLTVVTLVASILYLRQQLSSKHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3H9</accession>
    <name>D3Q3H9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2333</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2333"/>
    <dbReference type="EnsemblBacteria" id="ADD42020">
        <property type="protein sequence ID" value="ADD42020"/>
        <property type="gene ID" value="Snas_2333"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2333"/>
    <dbReference type="eggNOG" id="COG1116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="AGLYPWR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="28619" checksum="C92F891F65A61D2B" modified="2010-04-20" version="1">MSQTAASLSVRDLGKTYTTGTRSVRAIDNLNFDVAAGELVCVVGPSGCGKTTLLRTIAGLLRPTTGELTVDGRGVTGTPPGTAVVFQEYGRSLFPWLRVGDNVALPLRDNSVGGAERRTRVREALEQVGLADAERSYPWQLSGGMQQRVAIARALAYRPRLLLMDEPFAAVDAQTRADLEDLVYRLWRDLGVTVVFITHDIDEAVYLGQRVLVLSAPPSRIREEITVDLPVERDQLTTRADPRFLALRTQIHQHIRESGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3N5</accession>
    <name>D3Q3N5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019523.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4305"/>
    <dbReference type="EnsemblBacteria" id="ADD43952">
        <property type="protein sequence ID" value="ADD43952"/>
        <property type="gene ID" value="Snas_4305"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4305"/>
    <dbReference type="eggNOG" id="COG3534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_615250_0_0_11"/>
    <dbReference type="OrthoDB" id="1844783at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048637" evidence="1">
        <location>
            <begin position="30"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="445" mass="46961" checksum="CE15A8D38D83A7B2" modified="2010-04-20" version="1">MRRSRVLAIAATLALTGGAVVTHTTTATADEAGVAVDFTRPTAQIETGDIGVTITGYGGLNYIVNSEDHRKALAAHGFDTMRIELRYETPGDHDSRIICGGDSCHKDYDGDTWMSAIRDKMNATPILVVPADADDAVSLYEHFAATGTVPKVIVGNELDAGNPPRMDAATYAGVFNEIATRIHAADASVQVGGPGTAHNNIGYLRTFLEKSGEHVDFVDYHDYGMGETRLPDAQLLAEAANYERDIAEVRTLIDSTVPNGSDVGIQIGEWNMDHGDKSPACSSMTSHLPTVWGAAALGTMLESEATALLFGDKNGCLGLTGEWGEGQGEDFVDINKPMPISHGVGMFTGEGLFRPFGTTMVATSTSDDLLYVFASADDKNIVVVNTATTETSTAMSFTGLDSGTAEVWQTTNAQRVPHRAGTADISGGGMTATLPARSVTTFVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q453</accession>
    <name>D3Q453_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_6320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021509.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6320"/>
    <dbReference type="EnsemblBacteria" id="ADD45938">
        <property type="protein sequence ID" value="ADD45938"/>
        <property type="gene ID" value="Snas_6320"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6320"/>
    <dbReference type="eggNOG" id="COG0303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010186_7_0_11"/>
    <dbReference type="OMA" id="SPYAPVM"/>
    <dbReference type="OrthoDB" id="651103at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01078">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="188"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="415" mass="42894" checksum="F473B48C2344FF35" modified="2010-04-20" version="1">MDHKSGGAEPVALAEFLSRVLGRVRPLPAIDLDLTQACGCVLAADVTAPGPLPAFDHATVDGYAVRMEDVAGASPERPVSLKVLGDVSASSWRPVRLIPGTCFAVAAGASLPSGTDAVIPLGWTDEGMAAVRVGQAPKRGNGLRRAGEERESGAVLAHNGQHVTPQLIALLAAAGVGDIVVRPTPRVVVIATGDELMDTGRVSQPGQLVDVNSHALTAAASEAGAHAFRVGICDDEPEALRAVLDDQTLRADLIITTGGTGTGPGDMVRRTFGRDRTVEFSTVAVYPSATIGFGSVGPEEVPITCLPGDPGAAMNAFEVLARPIILRLAGAEPVFRPSVKANLIETVQSPANYREFRPAHVAERRGGGYTVAPLPGGPYTLSGLAEATGLMVLGEKVTTAPAGSTVDVLLFDRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q491</accession>
    <name>D3Q491_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_6360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021547.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6360"/>
    <dbReference type="EnsemblBacteria" id="ADD45976">
        <property type="protein sequence ID" value="ADD45976"/>
        <property type="gene ID" value="Snas_6360"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6360"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_5_1_11"/>
    <dbReference type="OMA" id="IHFYEAK"/>
    <dbReference type="OrthoDB" id="1677723at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01110">
        <property type="entry name" value="HTH_SoxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010211">
        <property type="entry name" value="Redox-sen_tscrpt-act_SoxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015358">
        <property type="entry name" value="Tscrpt_reg_MerR_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30204:SF0">
        <property type="entry name" value="PTHR30204:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09278">
        <property type="entry name" value="MerR-DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01950">
        <property type="entry name" value="SoxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH merR-type" evidence="7">
        <location>
            <begin position="11"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="152" mass="17122" checksum="E65A554A86FAC3A7" modified="2010-04-20" version="1">MKDVTLKFQDHLTVGEFADRAGVSAPTLRFYEKRGLITSERTSGNQRRYSRAELRRVAFIRTAQKVGLSLDEIASALAELPDARTPNKADWQRLSSRWQDRLNAKIRTLENLRDELTNCIGCGCLSLKSCAIANRYDELAAQGPGPRRLLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4A3</accession>
    <name>D3Q4A3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6372"/>
    <dbReference type="EnsemblBacteria" id="ADD45988">
        <property type="protein sequence ID" value="ADD45988"/>
        <property type="gene ID" value="Snas_6372"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6372"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_11"/>
    <dbReference type="OMA" id="SPMEIRN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="124"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="236" mass="25538" checksum="DCE66BB78FCB9699" modified="2010-04-20" version="1">MDLIILTNQAKAVPASVLPALDLLAHRVRCAKPDVGTLLSGPQSHTVLVDARTDLSEARATCRVLRTGGMTVPLIAVVTEAGLAGVHADWGIDDIIVNTAGPAEVEARLRLATGRLEVPPETGQSTVRVGDLTIDTETYAAKLKGRPLDLTYKEFELLRYLAQHPGRVFSREQLLREVWGFDYYGGTRTVDVHVRRLRAKLGSENESMIGTVRQVGYKFVAPPAKPLPDSAPVAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4D4</accession>
    <name>D3Q4D4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0377"/>
    <dbReference type="EnsemblBacteria" id="ADD40094">
        <property type="protein sequence ID" value="ADD40094"/>
        <property type="gene ID" value="Snas_0377"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0377"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1894909_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="66"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="134" mass="14695" checksum="567EF9A66FE6E089" modified="2010-04-20" version="1">MSTFATPDLRNPVVAWEVIARSAVHIVREARASRRLEPLSIDGRMLVNAVVALGIDLDVPKTVSIPASLRRGLSERETQVLLGIAGGKSNAEIGRELFITEDTVKTHARRMYRKLGARDRAHAVAEAFRIGILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4I9</accession>
    <name>D3Q4I9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015720.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0433"/>
    <dbReference type="EnsemblBacteria" id="ADD40149">
        <property type="protein sequence ID" value="ADD40149"/>
        <property type="gene ID" value="Snas_0433"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0433"/>
    <dbReference type="eggNOG" id="COG1878">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030671_0_0_11"/>
    <dbReference type="OMA" id="DVIAMPL"/>
    <dbReference type="OrthoDB" id="831439at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="SSF102198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="331" mass="35904" checksum="46D7418F7B8F088C" modified="2010-04-20" version="1">MQDWSRGWTPPDYRVDGDGKVIGATNPRAPHNWGRWGDLDELGTVNYITAKVRLAAAELVTTGEVVSCAIPIGDEMPVHPSRPAVVHTHALTGTDVVAGFVADRASGGFHGADDYVFMPLQSGTHWDGLTHGFGASTMYNGFWIGNVGADGARRLSTHLLADHMTGRGVLLDLPRAAGVDRLPGGHAITPAELDACAHAQNVELRSGDILLIRTGELGWFYSLDDKAPYWSGIHAGLSITTVDWIHRNEIAAIGIDNRTFEVTPFEPGHQETYPLHARLIRDLGLTIGELWWLDDLAEVCARDDRWEFMLTAPPLTVTGSSGSPVSPLAFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4J4</accession>
    <name>D3Q4J4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hly-III family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0439</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015725.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0439"/>
    <dbReference type="EnsemblBacteria" id="ADD40154">
        <property type="protein sequence ID" value="ADD40154"/>
        <property type="gene ID" value="Snas_0439"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0439"/>
    <dbReference type="eggNOG" id="COG1272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051078_2_2_11"/>
    <dbReference type="OMA" id="HEVFHSL"/>
    <dbReference type="OrthoDB" id="1659567at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="PTHR20855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="23228" checksum="BCE2E23DAC7CE4C0" modified="2010-04-20" version="1">MTAVINGPTKPRLRGLLHATAIPVAVIGAIVLVVIAPTIDGKIASAIYGLTSISLFGVSGFYHRSGNGYASEWLRRWDHANIYLIIAGTYTPFGVLALTGGAQLAVLLIIWIGAAAGVAFRTVWLGAPRWLYTSLYIVLGWVAIFFIPQFLEGVGLAAVILVVAGGLLYSLGAVVYGLKRPDPWPEVFGFHEIFHAFTVAAYLCQFSSVVLVVLASAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4M6</accession>
    <name>D3Q4M6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">8-amino-7-oxononanoate synthase</fullName>
            <ecNumber evidence="4">2.3.1.47</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0471</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.47" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015757.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0471"/>
    <dbReference type="EnsemblBacteria" id="ADD40186">
        <property type="protein sequence ID" value="ADD40186"/>
        <property type="gene ID" value="Snas_0471"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0471"/>
    <dbReference type="eggNOG" id="COG0156">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015846_11_2_11"/>
    <dbReference type="OMA" id="MDTHGFG"/>
    <dbReference type="OrthoDB" id="479874at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008710">
        <property type="term" value="F:8-amino-7-oxononanoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="3">
        <location>
            <begin position="32"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="370" mass="37868" checksum="5077BAB0BDE75A81" modified="2010-04-20" version="1">MIWQSTLDNKARLRRNAGLDRTLRVRAADDPLIDLAGNDYLGLARHPTVTAAAAEALAEYGLGAGGSRLVRGTTDAHVALENRLGELLGGAALVYSSGYLANLGAIRALCDASTMLVRDAHAHASLIDGCQLAGARLVTMPHNDIDALDRILAGHNRRSVVVVESVYSVDGDLAPLAELHRVCRAHGAILLVDEAHAVGVLGPGGAGASAASGLKAASDLVITATLSKALGSAGGVVAGPAELRRHLVDTGRTFIFDTAPPPAVAAGALAALELAAADDELRAEVSRRASAAAERLGVAAPAAGVVSVPASDPHAALEWARRCAEAGVAVGCFRPPSTPDGSSRLRLTVNAGIPVADFNNAIDVIERERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4P4</accession>
    <name>D3Q4P4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Uncharacterized N-acetyltransferase Snas_2391</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2391</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Homohexamer; trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the acetyltransferase Eis family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017645.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2391"/>
    <dbReference type="EnsemblBacteria" id="ADD42074">
        <property type="protein sequence ID" value="ADD42074"/>
        <property type="gene ID" value="Snas_2391"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2391"/>
    <dbReference type="eggNOG" id="COG4552">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050659_0_0_11"/>
    <dbReference type="OMA" id="HASCEIT"/>
    <dbReference type="OrthoDB" id="1497065at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01812">
        <property type="entry name" value="Eis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041380">
        <property type="entry name" value="Acetyltransf_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025559">
        <property type="entry name" value="Eis_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022902">
        <property type="entry name" value="NAcTrfase_Eis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17668">
        <property type="entry name" value="Acetyltransf_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13530">
        <property type="entry name" value="SCP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="5">
        <location>
            <begin position="6"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="4">
        <location>
            <begin position="81"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="4">
        <location>
            <begin position="89"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="4">
        <location>
            <begin position="114"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; via carboxylate" evidence="4">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="404" mass="43728" checksum="80540D83F0D4198E" modified="2010-04-20" version="1">MTTPEFSIRTANADEYERAARIFTSAMLFEFTPSEVGRARFEPERALIAEIDGEAAGVTKAMTRDLSIPGGVVPAAHISGVGVGQTFRRRGVLSGLMRRQLREVPEALAVLWASETAIYGRYGYAVASAELRLAAQLPQLGVKPVNDSGRLRAIEADTAATVLPPVLAEYQKQRPGVSGRRPVEWATTLDDPAEFRHGASARRITVHEDASGKVDGYALWRTKLEFDEAGVNGEVTVEEVVATTPEAYGALWSNLLTMDLCRKLNYMHAAVDEPVQQLVSNTRALSARWSDALWVRVTDVRRALEQRRFGAPIDLVLNITDDLIASNSGHFHLRGDIDKAHCEPTDAPADISLSVNELGSAYLGGRSLAEFAVTGKVTEHTPGAVHAASAGFGWPVAPGSIEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4W9</accession>
    <name>D3Q4W9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2466"/>
    <dbReference type="EnsemblBacteria" id="ADD42149">
        <property type="protein sequence ID" value="ADD42149"/>
        <property type="gene ID" value="Snas_2466"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2466"/>
    <dbReference type="eggNOG" id="ENOG5033I6X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049869_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="257" mass="27476" checksum="83CB43BE0EC91359" modified="2010-04-20" version="1">MTTDVYPNRTGKLALGWGIVAALAVAVSWGRGIAMDLMIAALSVVEFFGGDDVLEFEFDWIGGPLRALGTVAMAVLAWRVVRYQRVSKGACGRCGRDGTPGRDWRSLAKWAAWLTVLPAIGYAALKLYWGFGGMGGLADENLFGDVKPWSPGFADTAVMAAIGVGVALAMAYRLPRLPRWLLLTPAIIGCLMLLPVSVIGMAGNFTGANDFGPLGGLEPWVTWFVYGCFAVWAPCLTAVTLEYHYGTRGTCRACGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q532</accession>
    <name>D3Q532_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thiamin pyrophosphokinase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4436</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019652.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4436"/>
    <dbReference type="EnsemblBacteria" id="ADD44081">
        <property type="protein sequence ID" value="ADD44081"/>
        <property type="gene ID" value="Snas_4436"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4436"/>
    <dbReference type="eggNOG" id="COG4825">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046690_0_0_11"/>
    <dbReference type="OMA" id="MIIGDMD"/>
    <dbReference type="OrthoDB" id="1297228at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004788">
        <property type="term" value="F:thiamine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022215">
        <property type="entry name" value="SteA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036759">
        <property type="entry name" value="TPK_catalytic_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12555">
        <property type="entry name" value="TPPK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63999">
        <property type="entry name" value="SSF63999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="TPPK_C" evidence="6">
        <location>
            <begin position="337"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="396" mass="41955" checksum="B2B9B21AF2E29D0E" modified="2010-04-20" version="1">MRLPTLRRHDRASDWATGAVGGSAKLDRRTKRLVGRVNCGDIAVVDHMDIDRVAADSLVAAGVGAVINAKPSISGRYPNLGPEVLVSAGIVLIDEVGDEIFDRIDDGDKLRIEGGKVFRGEELLAEGRRLDAAAVAAAMAEARQGLAVQLEAFAANTMEYLNKERDLLLDGVGVPEVDTVFADRHCLIVVRGYDYKADLDVLRPYIREFKPVLVGVDGGADALVEAGYTPDLIVGDMDSASDEVLRCGAELVVHAYSDGHAPGMTRLEHLGVAAKVFPASATSEDIAMLLADEKGASMIVAVGTHATLVEFLDKGRSGMASTFLTRLRVGAKLVDAKGVSRLYRQRVPASGSFLLACSAIAGVAAAVALFTAGMSFAETGADWWDGMVSAIQRIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q539</accession>
    <name>D3Q539_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD-superfamily hydrolase, subfamily IIA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4443"/>
    <dbReference type="EnsemblBacteria" id="ADD44088">
        <property type="protein sequence ID" value="ADD44088"/>
        <property type="gene ID" value="Snas_4443"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4443"/>
    <dbReference type="eggNOG" id="COG0647">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043473_1_0_11"/>
    <dbReference type="OMA" id="PPMHRET"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041065">
        <property type="entry name" value="GNAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18407">
        <property type="entry name" value="GNAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GNAT_like" evidence="1">
        <location>
            <begin position="299"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="360" mass="37279" checksum="9A8C6406A337AE9D" modified="2010-04-20" version="1">MTKGPRGGSLDDGRLWGESLPLSRRYGLVLLDLDGVVYLLGEPIDGVPGALRELRRAGAVPVFVTNNASRRAAEVAELLSAKGVEASVAEVRTSAQVAAALLAEHCEPGSRVLVVGSEALAEEVAEAGLTPVESANGRKVAAVVQGYGRTVTWQRLAEAVVAVREGAWWLASNTDKTMPSPLGPLPGNGTLVAAVGTALGRQPDAVAGKPAPAMLRQAVAAHPGRDAIMVGDRWDTDIAGAHAAGLPGLLVLSGSISAPEVLELPPQGRPQFLAWTVAGINEPHPPVRVEAGEPTRFRCRDWSVSVTDGKSRLAGDGDALDALRALAQAAWWSRDRDAGVAGTPVADGESAARALARLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5Q1</accession>
    <name>D3Q5Q1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015771.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0485"/>
    <dbReference type="EnsemblBacteria" id="ADD40200">
        <property type="protein sequence ID" value="ADD40200"/>
        <property type="gene ID" value="Snas_0485"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0485"/>
    <dbReference type="eggNOG" id="COG0053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_424420_0_0_11"/>
    <dbReference type="OMA" id="NAMTTAG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049568" evidence="3">
        <location>
            <begin position="39"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="388"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="441"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="476"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="623" mass="66678" checksum="6CE8F961ACAD8024" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5X9</accession>
    <name>D3Q5X9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="6">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tsaD</name>
        <name evidence="8" type="ordered locus">Snas_0564</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015849.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0564"/>
    <dbReference type="EnsemblBacteria" id="ADD40278">
        <property type="protein sequence ID" value="ADD40278"/>
        <property type="gene ID" value="Snas_0564"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0564"/>
    <dbReference type="eggNOG" id="COG0533">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023208_0_2_11"/>
    <dbReference type="OMA" id="HLEGHIY"/>
    <dbReference type="OrthoDB" id="1257362at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="7">
        <location>
            <begin position="25"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="136"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="350" mass="36310" checksum="A36BFA07820B5F2F" modified="2010-04-20" version="1">MREPLILGIESSCDETGVGIVRGLELLANEVASSVEQHARFGGVIPEVASRAHLEAMVPTMRRALDVAGVKLSDVDAIAVTAGPGLSGALLVGLAAAKAYALAAGKPLYGVNHLDAHIAVDTLENGPLPKPSLGLLVSGGHTELLYVEDLAGKVRLLGQTLDDAAGEAYDKVGRILGMPYPAGPHIDAAARLGDPTAIDFPRGLTGPRDLAKHRYDFSFSGLKTAVARWIEARQREGAEIPVNDVAASFQEAVCDVLTAKAIDAAREHGIDTLLLGGGVAANSRLRELAQERCDAAGLTLRFPSRKLCTDNGAMVAALGSHLVAAGVTESRMDIPADSSLAVETVSLANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q607</accession>
    <name>D3Q607_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Extracellular solute-binding protein family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0592</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial solute-binding protein 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015877.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0592"/>
    <dbReference type="EnsemblBacteria" id="ADD40306">
        <property type="protein sequence ID" value="ADD40306"/>
        <property type="gene ID" value="Snas_0592"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0592"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_18_2_11"/>
    <dbReference type="OMA" id="GSIHERF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018313">
        <property type="entry name" value="SBP_3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01039">
        <property type="entry name" value="SBP_BACTERIAL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048258" evidence="4">
        <location>
            <begin position="25"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="5">
        <location>
            <begin position="47"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="PBPe" evidence="6">
        <location>
            <begin position="47"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="272" mass="29784" checksum="D00D0BFE05013771" modified="2010-04-20" version="1">MIRPNYARLLAVGLVVAVGMTVAACGGGAEKTKTPGGYTVELIDAKKLTVCTNIPYVPFQFEKNGKTVGFDVDMVDLAADELGVKQDVIDVKWDNIENGSALSGGKCDLAAAAMTITPEREKNLTFSEPYFDEVIAFVAPKGKAPKSVEDVGDRKLGVQASTTSLEYAKKHKLEPQEFEDSAKQRAGLESGKVEVVLQDYPVITEWMKDEKFAAKYEVGQIIETGSQYGFGFKKSADKTLVKVVNDQIKKAKDSKKYDELYKKWFGTEPKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6C1</accession>
    <name>D3Q6C1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017867.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2618"/>
    <dbReference type="EnsemblBacteria" id="ADD42296">
        <property type="protein sequence ID" value="ADD42296"/>
        <property type="gene ID" value="Snas_2618"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2618"/>
    <dbReference type="eggNOG" id="ENOG5030W2U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1884515_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="135" mass="15416" checksum="D99FDF2D26DE4129" modified="2010-04-20" version="1">MAKQLNPMPPSAKAARRTLWIQVLIALLLGGALAAAQRWNKFQTWIPQLVDDRVYRVAAGLAIGAVVLLLLTFLMRYQWRWLWILLLLIELASIAGLIWCGVKGVNWFLAIALSFVSLIALLTLNARRCRRWFHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6J2</accession>
    <name>D3Q6J2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3152 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4591</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4591"/>
    <dbReference type="EnsemblBacteria" id="ADD44235">
        <property type="protein sequence ID" value="ADD44235"/>
        <property type="gene ID" value="Snas_4591"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4591"/>
    <dbReference type="eggNOG" id="COG5479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037318_0_0_11"/>
    <dbReference type="OMA" id="PKSWTHN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022603">
        <property type="entry name" value="DUF3152"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11350">
        <property type="entry name" value="DUF3152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3152" evidence="3">
        <location>
            <begin position="113"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="32720" checksum="89477060A831C7A6" modified="2010-04-20" version="1">MDPPRLRNVDPRLGGGDSEDRPRASARTDRVLARRRMWRKRRRAILLAVLLMMFSIAGVKVVRAATGADSSDAADYLTSHVADDSPSESASPTPSRTPSASATPSDKPVVVDEGNGKWSYAKKPDKSEKFGDEGTLLSYNVAVEGDIHADVKEFSEVIADTLADDRGWTAGDDWRFKPIGKSGQADFTVYLASPKTRAKLCGSEDSYTSCRNGDAVVINLERWLLGVPHWKKSLDSYRQYVINHEVGHRLGEGHVTCPKKGKPSPVMAQQTLELRGCQPNAWPYLDGKYVTGPAGEYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6U0</accession>
    <name>D3Q6U0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0625</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015910.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0625"/>
    <dbReference type="EnsemblBacteria" id="ADD40339">
        <property type="protein sequence ID" value="ADD40339"/>
        <property type="gene ID" value="Snas_0625"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0625"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="MPRRNGI"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="216" mass="23012" checksum="426F6B1E8783B3C3" modified="2010-04-20" version="1">MTITVLLADDDPLARTGLRTLVSAQPDIDVIAEAADGTQVLPLVRRLRPDVVLMDVRMPDMDGIEATRRLRRDLTEPPKVVVITTFENDEYVFDALRAGANGFVLKRAPATEIAHAIRTVASGDALLFPEAIRALAAARPAPPGNPHGPIALTAREAEVLRLMATGLSNQDIATHLTVSLETIKTHVGSVLTKLGAANRTQAVIIAYESGFVTPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q776</accession>
    <name>D3Q776_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2670"/>
    <dbReference type="EnsemblBacteria" id="ADD42347">
        <property type="protein sequence ID" value="ADD42347"/>
        <property type="gene ID" value="Snas_2670"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2670"/>
    <dbReference type="HOGENOM" id="CLU_1271630_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="217" mass="23930" checksum="8AC3F738CC68C76E" modified="2010-04-20" version="1">MQFVLSTIANFVATVARQTRNALLRKQTGTFSLKVLLFCGRSPTTTSPPGCCIVASLAIAINKARLLGALGLATAATACHCNVAAAQEVTTYRTSPVCSLEQPPRRSPTVTQLLARLPPEQPQSRMPRQPGNDEYSHFLLEVFSWRTKVVAPPRHGVRHPHTAPHMQPHTVGRRSEMNRMATRRTQRRRPHRCANLSENTGNPTKKHGPHSADHVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q789</accession>
    <name>D3Q789_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2683"/>
    <dbReference type="EnsemblBacteria" id="ADD42360">
        <property type="protein sequence ID" value="ADD42360"/>
        <property type="gene ID" value="Snas_2683"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2683"/>
    <dbReference type="HOGENOM" id="CLU_2083419_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022536">
        <property type="entry name" value="EspC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10824">
        <property type="entry name" value="T7SS_ESX_EspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="117" mass="11728" checksum="24334B1A87204156" modified="2010-04-20" version="1">MNEPLNVVPSKMVAHGDNIAAIGGQMGTVADTANTVSAADGADAFGPLFAPFVVPLLSMAEEAAKGFINAAKETVGIQSQAVCGLAVTYTNTDQDGGQGIDQTSQGLSTNEITGAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q797</accession>
    <name>D3Q797_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Snas_2691</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017939.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2691"/>
    <dbReference type="CAZy" id="GT51">
        <property type="family name" value="Glycosyltransferase Family 51"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42368">
        <property type="protein sequence ID" value="ADD42368"/>
        <property type="gene ID" value="Snas_2691"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2691"/>
    <dbReference type="eggNOG" id="COG0744">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006354_6_1_11"/>
    <dbReference type="OMA" id="MNAYLAD"/>
    <dbReference type="OrthoDB" id="652304at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="11">
        <location>
            <begin position="124"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="10">
        <location>
            <begin position="397"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="674"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD42368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="711" mass="75933" checksum="E1EE8EE671A3473A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7C4</accession>
    <name>D3Q7C4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017966.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2719"/>
    <dbReference type="EnsemblBacteria" id="ADD42395">
        <property type="protein sequence ID" value="ADD42395"/>
        <property type="gene ID" value="Snas_2719"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2719"/>
    <dbReference type="HOGENOM" id="CLU_2920553_0_0_11"/>
    <dbReference type="OrthoDB" id="2225024at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="61" mass="6755" checksum="94A3489050B86283" modified="2010-04-20" version="1">MEPIASMIGVEMTRRLAHSAMPDAPVQPERPSRPKRVGPVRRSAASTLRRVANRLEPVPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7D7</accession>
    <name>D3Q7D7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycine dehydrogenase (aminomethyl-transferring)</fullName>
            <ecNumber evidence="2">1.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2732</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017979.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2732"/>
    <dbReference type="EnsemblBacteria" id="ADD42408">
        <property type="protein sequence ID" value="ADD42408"/>
        <property type="gene ID" value="Snas_2732"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2732"/>
    <dbReference type="eggNOG" id="COG0403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004620_0_2_11"/>
    <dbReference type="OMA" id="MYDGASA"/>
    <dbReference type="OrthoDB" id="870147at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023010">
        <property type="entry name" value="GcvPA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42806">
        <property type="entry name" value="PTHR42806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="442" mass="47746" checksum="E2546EAC40158A9E" modified="2010-04-20" version="1">MPHPYIPNAEPQVKAEMLAATGATDIEDFYADIPEHLRLRRPLDLPEPLRGEADLVRHVGGLLDRNTSTAEALSFLGAGCYRHYVPAVCDEVNSRSEFLTAYAGEPYEDHGRFQAMWEYQSMMGELLEMDVVNVPTYDGFQAAATALRMAGRITGRGRVVIATPIDPDKLSKIEDYLDGALTIGGELDGDDLAAVFVDYPSYLGVVDRKTAEYVRTAHDLGALAVVACDPVALGVLAPPASFGADIVCGDIQPLGMHPQYGGGHAGFIATRDEERFVMEFPSRLFGIVPTTVEGEYGFGDVAWDRTSLGVREQGREWVGTAAALWGITAGVYLALMGPQGMRELGEGLMSRCAYAMSRIGEIPGVEIVDAALPHIKEFAVRFTGGATVAMVNAALHERGIFGGKDLSADFPELGQSALYCVTEMHTKADIDRLAAELKEIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7H0</accession>
    <name>D3Q7H0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019883.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4669"/>
    <dbReference type="ESTHER" id="stanl-d3q7h0">
        <property type="family name" value="HNLyase_Bact"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44312">
        <property type="protein sequence ID" value="ADD44312"/>
        <property type="gene ID" value="Snas_4669"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4669"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046066_3_3_11"/>
    <dbReference type="OMA" id="PGDWWEN"/>
    <dbReference type="OrthoDB" id="1573721at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="4"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="24078" checksum="EE095DA04DFA5E1E" modified="2010-04-20" version="1">MSTFVLIHGANSSSWDWHLVAPELRALGHEVIAPDLPTGSPTATLTDYTDAVVKGIEDHDPKVPDDLVVVAHSLGGFTAPLVCHRVPARLLVLVNGMIPRPGETVADWWSNTGQSEATAGTDYDEHETFFHDVTPELEAKALAQVTGQGEAAMLQPWPAESWPEVPTKHLVGRDDRLFPAVWARGLARQRLGITTDEMDGGHYLALSRPAELALRLDAYTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7L9</accession>
    <name>D3Q7L9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019932.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4718"/>
    <dbReference type="EnsemblBacteria" id="ADD44361">
        <property type="protein sequence ID" value="ADD44361"/>
        <property type="gene ID" value="Snas_4718"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4718"/>
    <dbReference type="eggNOG" id="COG3963">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_982248_0_0_11"/>
    <dbReference type="OMA" id="GFLMPVM"/>
    <dbReference type="OrthoDB" id="1609500at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="316" mass="34833" checksum="42FE0FB1D8D538AB" modified="2010-04-20" version="1">MIEQLWDAYREHHDLAKLEGHCHTGRDWFYLAVLAFADGHDAAAADYATRAARHETASRVHAAAAEYLTKVGKQGRQQVYTEPEGFAAFIRGGGNVSLYRALSAALAERYRSAKPASLLDIGVGDGLALLPALTGDVARVDLLEPSAALLDATAAALTERGVAHRAANATLQQLATGVDAWPADTRWELTQSTFALHNIARPQRLELLGWLRDHTDRLLIAEFDLRPGSSCEPEWFDYVATRYEAGLAEYDGDGGLVAQGFLMPVMFGYFDPATVHHEQSLADWRADLTAAGFTDQREPELLHDYWWAPGYLLDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7X1</accession>
    <name>D3Q7X1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <shortName evidence="5">HMBPP reductase</shortName>
            <ecNumber evidence="5">1.17.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ispH</name>
        <name evidence="7" type="ordered locus">Snas_0764</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24488"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24825"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IspH family.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.4" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0764"/>
    <dbReference type="EnsemblBacteria" id="ADD40476">
        <property type="protein sequence ID" value="ADD40476"/>
        <property type="gene ID" value="Snas_0764"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0764"/>
    <dbReference type="eggNOG" id="COG0761">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_570965_0_0_11"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00097"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13944">
        <property type="entry name" value="lytB_ispH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00191">
        <property type="entry name" value="IspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30426">
        <property type="entry name" value="PTHR30426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00216">
        <property type="entry name" value="ispH_lytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="226"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="434"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="478" mass="50773" checksum="6B8D14ED71E10A26" modified="2010-04-20" version="1">MTTEARTVVLASPRSFCAGVERAIEIVELALERFGAPIYVRKQIVHNTHVVARLEGEGAIFVDDLDAVPDGACVVFSAHGVAPSVRAEAESRGLDVIDATCPLVAKVHTEARRFAERGDTILLIGHSGHEEVEGTMGEAAGIRLVESLADVDSLTVEDPSKVAYLTQTTLSVDETAEIIAALRRRFPKLRGPGGDDICYATSNRQEAIVEVAREADLVLVVGSRNSSNSRRLTEVAATAGTPAHLIEDAGQIRTEWLTGARVIGLSAGASAPPHLVEAVIAHLRGFGPVTVTERHTVEENVTFSLPLVVRQPLGVLLAPFLERLRLGVDELADGGTGQQLRQERRRTGQVEGQLDDRGAVRAGFGDVVGAQPQPAGIACLPGEGLALLHLGDGPDPVALLGLDHLGGVADPQTVLMGGFHGRHGRRPLRPVLQVGDRPPDQVDRRLDGESDVVKHGDSSRSSVITIIRPQSLGRFSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q802</accession>
    <name>D3Q802_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane-flanked domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016078.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0795"/>
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        <property type="protein sequence ID" value="ADD40507"/>
        <property type="gene ID" value="Snas_0795"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0795"/>
    <dbReference type="eggNOG" id="COG3402">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111473_0_0_11"/>
    <dbReference type="OMA" id="HGVIWGI"/>
    <dbReference type="OrthoDB" id="1750498at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
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        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="82"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="175" mass="19982" checksum="B1E6E20982EC3C87" modified="2010-04-20" version="1">MGFPDNLLAEDEEVVLHMHPHWKELIGPVFWFIVFALVAVFGYTAIPDDWGSWVPIARWIIVALAVIAIIWLSITPWVVWGTSHYVFTTHRLLLRTGLLTRKGRDIPYARVNDVSFEQGVIQRMFRLGTLMVQSASEQGAVVFKDMPKVEMVQSTLYKLVEEDRNRRTGVDDGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q844</accession>
    <name>D3Q844_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0837</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0837"/>
    <dbReference type="EnsemblBacteria" id="ADD40549">
        <property type="protein sequence ID" value="ADD40549"/>
        <property type="gene ID" value="Snas_0837"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0837"/>
    <dbReference type="eggNOG" id="COG2315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_138549_2_0_11"/>
    <dbReference type="OMA" id="PYIGHHG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007351">
        <property type="entry name" value="YjbR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038056">
        <property type="entry name" value="YjbR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04237">
        <property type="entry name" value="YjbR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142906">
        <property type="entry name" value="SSF142906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="129" mass="14378" checksum="6FEB2D6E833C1E89" modified="2010-04-20" version="1">MFVASLAKLRQLCLALPETTEVGVGDDPTFGVKGQTFATCHRVGDRESVWFKASPRTRSRLLSNGDDRRFFTPPYVGQHGWIGAWIDENCDWSQLDALLRESYQMTAPDAQGDNASRRENATTLIARAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q861</accession>
    <name>D3Q861_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0855</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016137.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0855"/>
    <dbReference type="EnsemblBacteria" id="ADD40566">
        <property type="protein sequence ID" value="ADD40566"/>
        <property type="gene ID" value="Snas_0855"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0855"/>
    <dbReference type="eggNOG" id="COG1127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="GMVFQYS"/>
    <dbReference type="OrthoDB" id="1058434at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030296">
        <property type="entry name" value="MlaF/Mkl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43023:SF6">
        <property type="entry name" value="PTHR43023:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="5"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="273" mass="29761" checksum="7817E5EF43058635" modified="2010-04-20" version="1">MGVGAEVVGLTKSFNGNKPVWSDVSLTVPSGDITVLLGPSGTGKSVFLKTLIGLLRPDRGKVFIDGQELTAMSDRELYAIRQRCGVLFQDGALFGSMNIYDNIAFPLREHTRKTEREIRRIVMQRLDVVGMVGDEDKLPSEISGGMRKRAGLARALVMDPELILCDEPDSGLDPVRTALLSKTIAELNAETGATFLIVTHDINTARTLPHHIGMLYLGQLVAFERREQMLASDKPVVRQFLNASIEGPIGMTEEKDANGQNGQTAQQPFGVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q871</accession>
    <name>D3Q871_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2769</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018016.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2769"/>
    <dbReference type="TCDB" id="2.A.1.21.11">
        <property type="family name" value="the major facilitator superfamily (mfs)"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42445">
        <property type="protein sequence ID" value="ADD42445"/>
        <property type="gene ID" value="Snas_2769"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2769"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_2_0_11"/>
    <dbReference type="OMA" id="MVVNIPM"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="14"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="13"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="417" mass="41346" checksum="C4AD2DDAB9C5FF5E" modified="2010-04-20" version="1">MSVQIGQSADRRPLVGLLASTTLSITGNAIVAVAVPWVVYARTGSATVAGLAGAAAILPVALSSLFGGALIDRFGRTVCAVAADLCSAAAVAALPLLDSLVGLGTGLILTLVALGAVFDGPGTAARESLRPDVARVTGTELTKVNAWGEAAESVGNMVGPGLGGILIAALGGFGALWVTVALFLASALLTVLAVPRTISPPPRPQPYLRAVAEGLKFVVREPGLRAVALTATIIVAFIAPFESVVLNAHLQATGAASQYGLILTAFALGGLAGAVGYGFAAHRLTERGTLIASVSLVGLGIAGFALLPPVPVMLALGLAVGVAAGPINPIAAVIMQRRTPERLRGRVIGSYTSLALAAGPLGLLVMGPVVDTGGPATGFAVIGAGCLLAAVFAGTARGLRGGQTADEPDPTTKEGTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8C1</accession>
    <name>D3Q8C1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2819</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018066.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2819"/>
    <dbReference type="EnsemblBacteria" id="ADD42495">
        <property type="protein sequence ID" value="ADD42495"/>
        <property type="gene ID" value="Snas_2819"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2819"/>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_1_1_11"/>
    <dbReference type="OMA" id="MDYAMAT"/>
    <dbReference type="OrthoDB" id="1942521at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048308" evidence="1">
        <location>
            <begin position="41"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="67"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="349" mass="37980" checksum="79CD7AE67551C557" modified="2010-04-20" version="1">MSTVSRPPRRPARPLLALLAIVLTVSTLSACGLLSEDSGADGSESGSFPVTIDHALGEAKIEKKPKRVVTIGWLSQDVVAALGTVPVGVTDFSWGSVDKYLPWFAERVKELDGEMPELIEVNDSDEASAEQILDLDPDLIVAAHSGITDSNYKKLSSIAPTIAYDKKPWQSDWKDVTLTVGTAMGQKKQAQKLLDETEKLIADTAEDNPKFTKTSFAYGWYLEEGSTELPLYVSADPRVQFVQQLGFKLSPQVADKESDPGTFTASFSLEEVDTIKADVYIGWVDNKKDLNRTVDNAVLKKWKPFASDSYYIMEDQAVAWASSAPSVLGIPWAMDDIVAGLDKAVAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8D7</accession>
    <name>D3Q8D7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018082.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2835"/>
    <dbReference type="EnsemblBacteria" id="ADD42511">
        <property type="protein sequence ID" value="ADD42511"/>
        <property type="gene ID" value="Snas_2835"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2835"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_4_11"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="181" mass="20480" checksum="BA74ADFB68910753" modified="2010-04-20" version="1">MWPTMDIDLDNLRLRTLTEADAPAVVEATSAETEPSFWGPRPVGPYSLAEAKNALREWDPDSDGQVSFGAFSDNRLVGALGLMPDAPQSAELAYWVRPEWRRRGIALRGITAVTQWAHEHAQLPRVWLEIRPDNAPSLRLAERAGFTFEERLAHHCRSWTADDPGQDTWHDCLIWSHTVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8G1</accession>
    <name>D3Q8G1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018106.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2860"/>
    <dbReference type="EnsemblBacteria" id="ADD42535">
        <property type="protein sequence ID" value="ADD42535"/>
        <property type="gene ID" value="Snas_2860"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2860"/>
    <dbReference type="eggNOG" id="COG2334">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072586_0_0_11"/>
    <dbReference type="OMA" id="WWERLND"/>
    <dbReference type="OrthoDB" id="1003984at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="24"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="336" mass="38337" checksum="3A5AB873C0857AF9" modified="2010-04-20" version="1">MDPSSIPAPASILPYWELGTVESIKRVPTGLMNRSWRVETDTGPYLLKLFLDVQGEQLAFQFEVLRALAGARVPVVLPVPSNHNTDSLIFDGNEFGVFPWLKDGRHRSGLSMSLERCRDLGRVLGSIHLTLSKAVPTPRQPFFQPSIPVEQAMDRVDRLLDLIDSRHGGSSFDALAERTLRMKRGLLAKLAHRRPPDIPVMSSGYLHGDLHPHNLLLDGDDRVLAVLDWDRLRVGPHSKELVRAAAFFFTHGDERGIDLKRAAEFIDGYRDIYDLGAPEIRIALHRLWWERLADNWVIEWHYMRRNQACDHLLPGQTALVKWWTANFDEVMHTLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8P5</accession>
    <name>D3Q8P5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">5'-Nucleotidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4846</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4846"/>
    <dbReference type="EnsemblBacteria" id="ADD44487">
        <property type="protein sequence ID" value="ADD44487"/>
        <property type="gene ID" value="Snas_4846"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4846"/>
    <dbReference type="eggNOG" id="COG0737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005854_5_2_11"/>
    <dbReference type="OrthoDB" id="1884225at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="3">
        <location>
            <begin position="34"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="4">
        <location>
            <begin position="378"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="578" mass="61900" checksum="98E364FE09EC1B13" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Y6</accession>
    <name>D3Q8Y6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0884</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016166.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0884"/>
    <dbReference type="EnsemblBacteria" id="ADD40595">
        <property type="protein sequence ID" value="ADD40595"/>
        <property type="gene ID" value="Snas_0884"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0884"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_11"/>
    <dbReference type="OMA" id="QRYFTES"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="79"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="291" mass="31190" checksum="11F55EDFB8F9672F" modified="2010-04-20" version="1">MTVKKTKGLNQGSTGMRVFRYAVLLIFVLLFLMPIYVVVVTSLKAPDEVSVPGMWELPTSLSFANFGDALGKPEIYNGLVNSVIVALISSVVSSLMGASNGFVLSKWRFPGANVVFSLMLFGMFIPYQAVLIPMTQFMTNTGLMGGGEPTGGLAALIIAHIVYGLPITTLIFRGYYAGVPDTIFESARVDGAGMLRSFWSIGLPLALPAFAVSIIWQFTSAWNDFLFGVVMTTNNTSWPVTIGLNNIAGAQTVPFGETMAAALIASLPTLLVYIILGRFFMRGLMAGALKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9A0</accession>
    <name>D3Q9A0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_2907</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018153.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2907"/>
    <dbReference type="EnsemblBacteria" id="ADD42582">
        <property type="protein sequence ID" value="ADD42582"/>
        <property type="gene ID" value="Snas_2907"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2907"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_1_2_11"/>
    <dbReference type="OMA" id="LSYLWTW"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="9"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="135"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="247"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="405" mass="44926" checksum="4652599441D70D73" modified="2010-04-20" version="1">MAELFAVSDRAKAYQEDLREFMTSHIYPAEPVYDRQMRESGDPHFQPPVLEELKAEAKKRGLWNLFHPHPEWGPGLTNLEYAPLAEIMGRSFIAPEACNCNAPDTGNIEVLTLFGTPEHHRLYLKPLLDGTMASAFAMTEPDVASSDATNIELRMERDGDDYVLNGRKWFASNALHKNCRVLIVMGKTDPTAAPHRQQSMVVVPIDAPGITVVRNLPVFGYLDREGHAELTFDNVRVPASDMLKGEGEGFAISQARLGPGRVHHCMRTIGMAERALELLCTRALSRSTFGKPLSTRANIQDWIAEARIEIDMARLLTLKTAYLMDTMGNQAAATEISAIKVAAPQAALNVIDRAIQVHGGAGVTDDFPLAMAWAHLRALRLADGPDEVHKRAIARRELRKYDVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9D4</accession>
    <name>D3Q9D4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2941"/>
    <dbReference type="EnsemblBacteria" id="ADD42616">
        <property type="protein sequence ID" value="ADD42616"/>
        <property type="gene ID" value="Snas_2941"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2941"/>
    <dbReference type="HOGENOM" id="CLU_1958241_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="128" mass="13678" checksum="4A1C15EA41AC9577" modified="2010-04-20" version="1">MPLIQIQSLPLPADDDAAQLRTHRLLRTYLENAGIGDVESVQADAAPEGARSSGGILLNIFNIVLNPVFSGAASVVVTMLFEYVRRGKRPVTVKVNGAEFTFDATTIQQNPDLVAKLLSAAIGEEDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9F5</accession>
    <name>D3Q9F5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GtrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2962</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GtrA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018208.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2962"/>
    <dbReference type="EnsemblBacteria" id="ADD42637">
        <property type="protein sequence ID" value="ADD42637"/>
        <property type="gene ID" value="Snas_2962"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2962"/>
    <dbReference type="eggNOG" id="COG2246">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1766898_0_0_11"/>
    <dbReference type="OMA" id="WTWSARR"/>
    <dbReference type="OrthoDB" id="2209336at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="7">
        <location>
            <begin position="15"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="147" mass="15675" checksum="72A6557F9FA32BFF" modified="2010-04-20" version="1">MPTPRPSPIGLRLSRFALVGLSCFATQVVVMTWLAALGMTLPLANAIGFVVSAQANFGLSAWFTWGDRPARSRPRVLARRWLSYQATAGLALVVNTVTFTVALPSVPPVIAAAAGVVVGSGVTFVVCHFLIFTAAPLRRRLPAEETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9J6</accession>
    <name>D3Q9J6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3007</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018249.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42678">
        <property type="protein sequence ID" value="ADD42678"/>
        <property type="gene ID" value="Snas_3007"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3007"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_0_1_11"/>
    <dbReference type="OMA" id="AWWEQGL"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="30"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="239" mass="25864" checksum="3724976357529BB5" modified="2010-04-20" version="1">MTDNAASAVPNSLQAAWGVRERPGFGPRPGLSLDRIVAAALELAESDGLAAVSMVKVAKALDVSTMALYRYVAAKDELLELMVDAGFGEPPPGPEGADWREGLAAWVWDCLTAWRRHPWMLHVPVSGPPLTPHQIAWLERGLTCLADTGLSERERLSVVMMASGLVRGWANVTVGADEGRDPAYYATTLSRLIDPLRFPAVTAAMAAGAIDDDTDDPDEEFRFQLERLLDGVQALITRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9T9</accession>
    <name>D3Q9T9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">3-isopropylmalate dehydratase small subunit</fullName>
            <ecNumber evidence="10">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Alpha-IPM isomerase</fullName>
            <shortName evidence="10">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">leuD</name>
        <name evidence="12" type="ordered locus">Snas_4998</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the LeuD family. LeuD type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020206.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4998"/>
    <dbReference type="EnsemblBacteria" id="ADD44635">
        <property type="protein sequence ID" value="ADD44635"/>
        <property type="gene ID" value="Snas_4998"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4998"/>
    <dbReference type="eggNOG" id="COG0066">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081378_0_1_11"/>
    <dbReference type="OMA" id="AFTTHTG"/>
    <dbReference type="OrthoDB" id="1384217at2"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009316">
        <property type="term" value="C:3-isopropylmalate dehydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01031">
        <property type="entry name" value="LeuD_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase_C" evidence="11">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD44635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="198" mass="22251" checksum="A738B76C962EC86D" modified="2010-04-20" version="1">MQSFTVHTGRALPLRRSNVDTDQIIPASYLKRVTRTGFADGLFASWRGDPDFVLNRDAYAESTILVTGTEFGTGSSREHAVWALQDHGFRAVIAPRFGDIFRGNALKGGLLPVELDTSAVEWLWDAVEADPSIEVTVDLERREVIAGQQVWKFDLDDHSRWRLLEGLDDIDLTLRDESAITAFESERPLWLPRTLPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9U4</accession>
    <name>D3Q9U4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-lactate dehydrogenase (Cytochrome)</fullName>
            <ecNumber evidence="2">1.1.2.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.2.4" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020211.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5003"/>
    <dbReference type="EnsemblBacteria" id="ADD44640">
        <property type="protein sequence ID" value="ADD44640"/>
        <property type="gene ID" value="Snas_5003"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5003"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017779_9_2_11"/>
    <dbReference type="OMA" id="YIVQDGV"/>
    <dbReference type="OrthoDB" id="1188552at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="37"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="483" mass="49829" checksum="9CCB3BD7AA451A40" modified="2010-04-20" version="1">MDVTGLAPAFREIVGADAVITDHQELRTYECDGLTSHAAVPGIVVLPTSADQVARIVRTCVAEGVPYVARGSGTGLSGGALPRADGVLIVTSRMRRVLGVDVANRIAVVEPGVVNLAVTRAASPSGYYYAPDPSSQQICSIGGNVAENSGGAHCLKYGFTVNHVLGLEIVTPQGELVRLGGPAVQYPGYDLVGAFVGSEGTLGIATEVTVRLLRAPEDVATLLAAFDSIDAAGACVSAIIAAGIIPAAIEMMDATAIAAVEAAVACGYPPGAAAVLIVEVDGPAAEVAAQLDQVRTLAAEAFDIRVAADDTERAAIWKGRKSAFAAIGHTSPSYIVQDGVVPRTALPAVLSRIETLSRDSGIAVANVFHAGDGNLHPLVMYDDKVAGETERAEEVSAAILDLCLSHGGSLTGEHGIGVDKSRYMPRMFSDADLDTMQLLRCAFDPGGLCNPGKVFPTPRLCGERPGHRKGVHPLAESGKAELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA61</accession>
    <name>D3QA61_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016344.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1063"/>
    <dbReference type="EnsemblBacteria" id="ADD40773">
        <property type="protein sequence ID" value="ADD40773"/>
        <property type="gene ID" value="Snas_1063"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1063"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048478_2_0_11"/>
    <dbReference type="OMA" id="EFYLAHR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041516">
        <property type="entry name" value="LACTB2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17778">
        <property type="entry name" value="BLACT_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="30"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="255" mass="26548" checksum="0A0C97D0F24EE440" modified="2010-04-20" version="1">MTGITGLDTGSPPWVSLFRAPNPGPMTLDGTNTWLIAANAGHDALVVDPGPAIEEHLAAVAASGPIRGVLLTHHHPDHAEGLERFRELTGAGVVNPGPGQRLVHGDLTITTIATPGHTADSVSFHVGGASPAVFTGDTILGHGSTAVLWPDGNLGHYLDSLKRLRGLGPIPVLPGHGPVRRDAAAAATEYETHRQARLDQVRAALAAGAASPREVVEVVYADVDKSLWPAAEATVRAQLAYLEERDAEHIRPGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAI5</accession>
    <name>D3QAI5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3097</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3097"/>
    <dbReference type="EnsemblBacteria" id="ADD42768">
        <property type="protein sequence ID" value="ADD42768"/>
        <property type="gene ID" value="Snas_3097"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3097"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="AHPEIGC"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="222" mass="24112" checksum="BDF88D3CF91D83F7" modified="2010-04-20" version="1">MRDVTVRVFLVDDHEIVRRGLANVLEAEPEFTIVGEAATAAEAEARVPAADPDVAILDVRLPDGNGVEVCRELKSKLPKLNCLMLTSFADDEALFDAIMAGASGFVLKQVLGADLLGAVRTVATGQSLLDTKTTTALMNRLRREQSQVDPLCELSQQERKVLELIGLGLTNRQIAGRMFLAEKTVKNYVSHLLAKLGMTSRTQAAVLATEVRTGQRAPQEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAR7</accession>
    <name>D3QAR7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020284.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5077"/>
    <dbReference type="EnsemblBacteria" id="ADD44713">
        <property type="protein sequence ID" value="ADD44713"/>
        <property type="gene ID" value="Snas_5077"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5077"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_27_0_11"/>
    <dbReference type="OMA" id="TLYVYFD"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="23472" checksum="183DF99BF47BDD99" modified="2010-04-20" version="1">MDESTLDPRIVRSRAVIMTAASEHFLRKGYVGANVDEIAAEARVSKRTVYNIFGTKEQLFREILAEAFGTAERFSRETVSVLTDTDDLAGELKAVAVRLARIVLDPRVVRLRRLLIGEAERFPELAGEYYRRAPDRVMDTLAEAIGRLGERGLLRASDPRLAAEHFAFLVMGAALDRALFTVDGETLPQTEIETRAVAGVAAFLAAYKDENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAZ0</accession>
    <name>D3QAZ0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020357.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5151"/>
    <dbReference type="EnsemblBacteria" id="ADD44786">
        <property type="protein sequence ID" value="ADD44786"/>
        <property type="gene ID" value="Snas_5151"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5151"/>
    <dbReference type="HOGENOM" id="CLU_1266251_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="23211" checksum="7A4AFAF06548C6D9" modified="2010-04-20" version="1">MNDNDFATAIGGMFERQARNAPDSAGLLETVKARSRRRGIWRRVTAGASALAVTGAAALLTGQLLQPASHGGVPPHDRDVSVCFDVKDDVPQRLLLVETGEDGVDELEAAEWTGGESGSIEHPVNFGDYRVAVKAEDTPVEKLPIQASEEAELHFDSARIGTDAETGERVVAFDSGESVNGVDVSLVVTVVEGDPSDAELLTWIEAISVYINEPHCDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB52</accession>
    <name>D3QB52_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FolC bifunctional protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1159</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016440.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1159"/>
    <dbReference type="EnsemblBacteria" id="ADD40869">
        <property type="protein sequence ID" value="ADD40869"/>
        <property type="gene ID" value="Snas_1159"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1159"/>
    <dbReference type="eggNOG" id="COG0285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015869_1_2_11"/>
    <dbReference type="OMA" id="YFEMGTL"/>
    <dbReference type="OrthoDB" id="1232874at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="6">
        <location>
            <begin position="51"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="5">
        <location>
            <begin position="306"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="448" mass="47457" checksum="F2B8E9CC8B9D46DA" modified="2010-04-20" version="1">MTTAEEHSQYLAVSAALEARGFSRMNFDMNRIKALLEVMGDPQKSFRAIHITGTNGKTSTARIVESLLRAHGLRTGRYTSPHLDSVRERISVDGEPVSEERFTALYRELAPLAELVDARFDESMTYFEMTTALAFAAFADAPVDVAVVEVGLGGEEDATNVLGAEVAVVTPIGVDHTRWLGETLTDIATAKAGIIHPGSNLVTATQEPEAMIPLVERCHAVKAGLIAQGRSFDVADRKVALGGQQLALQGPSGSVYDGVFLPLHGKHQAQNAAVALAATEVLLGAGTPKTLDGEVVAEGLAEVTSPGRLERVRTAPVVLLDGAHNPAGMAATVAAVEEEFSLRRLIVVLGVFGDKNAVEMLRLLQPVCDHLVVTQSTSERAKPVAALAREAAEVFDDEQITVMPYLPDAIESAVTLAEEGEAAYGGAGVLITGSVHMVGDARKLLVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBP0</accession>
    <name>D3QBP0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3252</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018493.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3252"/>
    <dbReference type="EnsemblBacteria" id="ADD42922">
        <property type="protein sequence ID" value="ADD42922"/>
        <property type="gene ID" value="Snas_3252"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3252"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="ISTMLEH"/>
    <dbReference type="OrthoDB" id="664909at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="9"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="351" mass="37159" checksum="FF8807AB110B0560" modified="2010-04-20" version="1">MTGPALPRATLAEVAARAGVSKATASKVLNGRPGVSEETRRQVHQVIRELNYTPSTGPREATDHGTVHVVFDTIVNMYSPHVLDGVINAGRELGVDVVTSVLAPDGVIPDRSLGVDRIKEIAVRGHTGLIVVTTQLTGEEIATCENLGLPLVVIDPVNPLDERVISIGATNWAGGVQATRHLLGLGHTRIAFAGGAEHSVPGRERLHGYREALETAGIVPDPTLIRRGPFTSETGAEIGGYLLGLDEVPTAIFAASDAIAVGVIQVARSRGLRIPEDLSVVGFDDTYGAMWTDPPLTTVRQPLRQMGRVAARTLLDIADDKVPDSHHVQLATTLVVRDSTATPSASSRRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUC1</accession>
    <name>D3PUC1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016638.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1360"/>
    <dbReference type="EnsemblBacteria" id="ADD41067">
        <property type="protein sequence ID" value="ADD41067"/>
        <property type="gene ID" value="Snas_1360"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1360"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_6_11"/>
    <dbReference type="OMA" id="LMCERFL"/>
    <dbReference type="OrthoDB" id="1616572at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="6"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="288" mass="30168" checksum="A3E3EDE256A61AC8" modified="2010-04-20" version="1">MILVTGATGLVGTPLTELLARRGAKVRAVSRDPKAVVPQGVALVTGDPAKPDTIAEALDGVTALFLHPRAVGDAADALAALARRRGVSRIVALSATNVDDPLDEQPSRVRGDRNREAEDAAVAHGREWTSIRVGYFALNALTSWGGQIHNSDVVRGPYADFAVAPIHERDIAAVAAHALLTPDLVGRKVNLSGPAILRHADMVATIGTVLNRPLRYQEIPPEAAARALTGAGLPESLANAFVANYTRDWGLGAMATGEVERILGRGGLTFADWVADHADAFAAPTAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUH5</accession>
    <name>D3PUH5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-1,2-mannosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3322</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018559.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3322"/>
    <dbReference type="CAZy" id="GH92">
        <property type="family name" value="Glycoside Hydrolase Family 92"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42988">
        <property type="protein sequence ID" value="ADD42988"/>
        <property type="gene ID" value="Snas_3322"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3322"/>
    <dbReference type="eggNOG" id="COG1470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003690_2_0_11"/>
    <dbReference type="OMA" id="WEYGFFV"/>
    <dbReference type="OrthoDB" id="100818at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="Alpha_mannosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049242" evidence="2">
        <location>
            <begin position="30"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92N" evidence="4">
        <location>
            <begin position="38"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92" evidence="3">
        <location>
            <begin position="270"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="764"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1089" mass="116471" checksum="2371530DEF808702" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV87</accession>
    <name>D3PV87_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SNF2-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1434</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1434"/>
    <dbReference type="EnsemblBacteria" id="ADD41140">
        <property type="protein sequence ID" value="ADD41140"/>
        <property type="gene ID" value="Snas_1434"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1434"/>
    <dbReference type="eggNOG" id="COG0553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000315_21_8_11"/>
    <dbReference type="OMA" id="YVWEQCD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="168"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="447"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="621" mass="67907" checksum="9CA1C04F9B45F9B4" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVD3</accession>
    <name>D3PVD3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016757.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1482"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41186">
        <property type="protein sequence ID" value="ADD41186"/>
        <property type="gene ID" value="Snas_1482"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1482"/>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025996_0_5_11"/>
    <dbReference type="OMA" id="SHYAYEY"/>
    <dbReference type="OrthoDB" id="865276at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="301" mass="32678" checksum="00436D590B884DB6" modified="2010-04-20" version="1">MTEWPSIGVVIPTHNRPDLMRAALTSVLAQRYPGRLGAIVVFDRAKPDTTLEQDGDRPVRVLKNSRTPGLAGARNTGIAALDTDLVAFCDDDDVWLPGKLTAQVGAMEPATEMATCAINVAYRGRTTARLAGAAKVYQADLLRSRMMMLHSSTFLLRRSALLGGLGMVAEDAPGSQNEDWDLLLRAARRGPIVHVDSPYAKIHWGDSHFETRYDTKISSLRWMLQRHPELHGIPAGAARVYGQLSCWHAAVGDRAAALHWAGRATRAQWSEPRAVIGAAAALGLVKVPTVLSMLHARGRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVG6</accession>
    <name>D3PVG6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YCII-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018651.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3416"/>
    <dbReference type="EnsemblBacteria" id="ADD43080">
        <property type="protein sequence ID" value="ADD43080"/>
        <property type="gene ID" value="Snas_3416"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3416"/>
    <dbReference type="eggNOG" id="COG3795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130902_2_2_11"/>
    <dbReference type="OMA" id="QYALIIR"/>
    <dbReference type="OrthoDB" id="2051456at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="119" mass="13091" checksum="0960E8A4DEEED678" modified="2010-04-20" version="1">MRYMLLLNGEEPTTTPSEAEMNAEMAEWGAYDTAVHEAGIFVSSEALQPSQTATTVRLKDQERIVTDGPFVETREVLGGFYVIDVPDLDTALDWAAKCPAAKNGSVEIRPVLVFDEPEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW79</accession>
    <name>D3PW79_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1532</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016807.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1532"/>
    <dbReference type="EnsemblBacteria" id="ADD41236">
        <property type="protein sequence ID" value="ADD41236"/>
        <property type="gene ID" value="Snas_1532"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1532"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_3_5_11"/>
    <dbReference type="OMA" id="PRAWLMT"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="20"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="123"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="189" mass="21027" checksum="18403FD9C269E736" modified="2010-04-20" version="1">MTDPVAEALAKDLDHGYQTLYGEYRGVVFSTALRLAGRWADAEDIAAEAFLRAYRALLGYDTDRRASLRTRAWLLTIVMNVWRNRVRTLARKPPPGPIEDAPEPVDPSETVEETAERHDTGAQLARLLTVLPHRQREAVVLRHVVDLPIDEIAEILDIPQGTVKSHISRGLSRLRAEVTTTAISEGGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW91</accession>
    <name>D3PW91_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dITP/XTP pyrophosphatase</fullName>
            <ecNumber evidence="6">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="6">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1545</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + ITP = diphosphate + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + XTP = diphosphate + H(+) + XMP</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016819.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1545"/>
    <dbReference type="EnsemblBacteria" id="ADD41248">
        <property type="protein sequence ID" value="ADD41248"/>
        <property type="gene ID" value="Snas_1545"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1545"/>
    <dbReference type="eggNOG" id="COG0127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082080_0_1_11"/>
    <dbReference type="OMA" id="DCFADDT"/>
    <dbReference type="OrthoDB" id="1824064at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009146">
        <property type="term" value="P:purine nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01405">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020922">
        <property type="entry name" value="dITP/XTP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="7"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="153"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="181"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="193" mass="20624" checksum="E559B636573CD7DC" modified="2010-04-20" version="1">MRLLLATRNRKKLTELERILAEHSAVELVGLGDVEEYPEAPETALTFAGNALAKARDAVRHTGLTCVADDSGIAVDALNGMPGVFSARWAGRHGDDEANLELLLGQLGDVPDEERGAAFVCAAALVRPDGSEEVVHGEVRGRIIREPLGDNGFGYDPIFVPDGFAVTTAQLSAVEKDAISHRGKAFRQLAKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWM0</accession>
    <name>D3PWM0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">pre-crRNA processing endonuclease</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018813.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3581"/>
    <dbReference type="EnsemblBacteria" id="ADD43242">
        <property type="protein sequence ID" value="ADD43242"/>
        <property type="gene ID" value="Snas_3581"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3581"/>
    <dbReference type="eggNOG" id="ENOG502Z82V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086014_0_0_11"/>
    <dbReference type="OMA" id="YLGCREF"/>
    <dbReference type="OrthoDB" id="1619114at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021124">
        <property type="entry name" value="CRISPR-assoc_prot_Cas5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013422">
        <property type="entry name" value="CRISPR-assoc_prot_Cas5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010155">
        <property type="entry name" value="CRISPR-assoc_prot_Cas5d"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09704">
        <property type="entry name" value="Cas_Cas5d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029950">
        <property type="entry name" value="Cas_CT1134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01876">
        <property type="entry name" value="cas_Cas5d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02593">
        <property type="entry name" value="CRISPR_cas5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR029950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="231" mass="25775" checksum="D3588D8AC7743A0C" modified="2010-04-20" version="1">MTPHGTAITLPTDPHGHRPVAVQVWGDAALFTRPELKAERLTYPVMTPSAAKGVLEAIYWKPEMAYQVVAIEVLKPIKQFTVRRNETNDVASLRDAAKGVRRIDTAAKRDQRNAVCLRDVAYRIHAHIRLQPHANKPVVAYRDQFRRRVDKGACFAQPYLGTREFTAYFGKPDGTPARDELDGDLGIMIHTVGYDGDHAMEWFTARLDRGVLRVPERGIVAEASHISAAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWX1</accession>
    <name>D3PWX1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5564</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5564"/>
    <dbReference type="EnsemblBacteria" id="ADD45195">
        <property type="protein sequence ID" value="ADD45195"/>
        <property type="gene ID" value="Snas_5564"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5564"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_25_6_11"/>
    <dbReference type="OMA" id="DDAWVDR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16859">
        <property type="entry name" value="TetR_C_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="22"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="201" mass="22274" checksum="A2397F259707D530" modified="2010-04-20" version="1">MELSVAYCWGVASGRLGRPREERVDEALAEAVRELLTETGYQNITVDLIASRAGVGKPAIYRRHRSKAELIFSVIVHDLSETAPDDAGSLRADLRSLLHRIHGDLSDPVAGSVMSSLLSDVLADPELTARFRDTFVRAQRDVVAELCRRAVDRGELKRLPEPEFAHSLLLGPLFVRHVILGERVPRSQLDDYLDAAVRALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX33</accession>
    <name>D3PX33_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020828.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5627"/>
    <dbReference type="EnsemblBacteria" id="ADD45257">
        <property type="protein sequence ID" value="ADD45257"/>
        <property type="gene ID" value="Snas_5627"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5627"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_6_11"/>
    <dbReference type="OMA" id="MANTREW"/>
    <dbReference type="OrthoDB" id="1616572at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="273" mass="29177" checksum="AD4ACAB826585F57" modified="2010-04-20" version="1">MTYLVAGATGTIGRHIIKHLLATGQPVRALTRNPDAASLPENVEVVTGDLSRPETLRAVFDGVTAAHLLSASGDDHTPLRTGAEIAALATRAGVQRVTAISPGLEGPLEQALAASELKWTLLWPIDYMANTLGWSQAIRDDGVVREPYGSRKTASVDESDIGAVAAHILINGGHDGQTYKLTGPQTLTPADKVNALATATGLPLNFAELTDDQARDLWRSQGWSEEGIEFMLNMWATVPDSVGHVNSSVEKILGRAPRSFTQWATEHANAFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX56</accession>
    <name>D3PX56_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_5650</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020851.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5650"/>
    <dbReference type="EnsemblBacteria" id="ADD45280">
        <property type="protein sequence ID" value="ADD45280"/>
        <property type="gene ID" value="Snas_5650"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5650"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016513_0_0_11"/>
    <dbReference type="OMA" id="GNVQCLD"/>
    <dbReference type="OrthoDB" id="433393at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041504">
        <property type="entry name" value="AidB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18158">
        <property type="entry name" value="AidB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AidB_N" evidence="8">
        <location>
            <begin position="12"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="181"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="285"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="542" mass="58464" checksum="B21EA92109AD58BE" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX68</accession>
    <name>D3PX68_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1628</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016902.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1628"/>
    <dbReference type="EnsemblBacteria" id="ADD41331">
        <property type="protein sequence ID" value="ADD41331"/>
        <property type="gene ID" value="Snas_1628"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1628"/>
    <dbReference type="HOGENOM" id="CLU_1905474_0_0_11"/>
    <dbReference type="OrthoDB" id="2182149at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="133" mass="13872" checksum="A67C1A3BE885AEBB" modified="2010-04-20" version="1">MGKKPFILMALGIFLIVGAFTFGVSDPTCGSGRGAPTMSPGEVCVNESTGEKQTYDEAKAQQNKQIRIGLPIVGGIMIVYGAFTAIKRKRDPNWRTANAKAQPVAAGQPVAPGQPVPPQQPHGGQPPQAPPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXK2</accession>
    <name>D3PXK2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein 70</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3675</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018903.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3675"/>
    <dbReference type="EnsemblBacteria" id="ADD43332">
        <property type="protein sequence ID" value="ADD43332"/>
        <property type="gene ID" value="Snas_3675"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3675"/>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_394770_0_0_11"/>
    <dbReference type="OMA" id="HLAPTTW"/>
    <dbReference type="OrthoDB" id="155921at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="508"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="557"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="598"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="632"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="664"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="355"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="698" mass="74709" checksum="86CD05AB62A76D9D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXS2</accession>
    <name>D3PXS2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3745</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018973.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3745"/>
    <dbReference type="EnsemblBacteria" id="ADD43402">
        <property type="protein sequence ID" value="ADD43402"/>
        <property type="gene ID" value="Snas_3745"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3745"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_8_11"/>
    <dbReference type="OMA" id="QEMRAPR"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="4">
        <location>
            <begin position="140"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="209"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="235" mass="24967" checksum="3A78E853D698F736" modified="2010-04-20" version="1">MSEPIRVLVADDHPIVRQGLKTFLDIQPDLSVVAEARDGDEALALIAAHEPDVVLLDLNMPGSDGAKVLTRLAASDHRAKVIVLTSVTEAVRVTEAVAAGAAGFLYKDIDPDSLAQAIRSVADGQVIFAREAVTAMTAPAPGPVAALTAREREVLALVAAGRSNREIAKQLSVAEKTVKTHLSSLFRKLGVADRTQAALYAVTHGMAGHTEGRLESPPRAGRQSAVHKRRVWEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXW7</accession>
    <name>D3PXW7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5666</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5666"/>
    <dbReference type="EnsemblBacteria" id="ADD45296">
        <property type="protein sequence ID" value="ADD45296"/>
        <property type="gene ID" value="Snas_5666"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5666"/>
    <dbReference type="eggNOG" id="COG1887">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_465163_0_0_11"/>
    <dbReference type="OMA" id="WTGHHAD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047355">
        <property type="term" value="F:CDP-glycerol glycerophosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007554">
        <property type="entry name" value="Glycerophosphate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043148">
        <property type="entry name" value="TagF_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04464">
        <property type="entry name" value="Glyphos_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="548"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="569" mass="61795" checksum="0666EF8E9BF299A8" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY73</accession>
    <name>D3PY73_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020973.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5772"/>
    <dbReference type="EnsemblBacteria" id="ADD45402">
        <property type="protein sequence ID" value="ADD45402"/>
        <property type="gene ID" value="Snas_5772"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5772"/>
    <dbReference type="HOGENOM" id="CLU_1676778_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="157" mass="17202" checksum="4CA03CBFFF3525E2" modified="2010-04-20" version="1">MGDKENNLGLELGQLWLCSRVLLPEAANVYVGMANKATETGNHTDAFNDTLYNGTAYASSPISAAWTELLGQFQDVMSISAQNLYDVCDVLDRTRESFAKNDGMNAEQIGSAMNETVQGYQNGDYRDKDVVEPGERPKPKDDGPGGLRDNPNYDRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYC8</accession>
    <name>D3PYC8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">DNA primase</fullName>
            <ecNumber evidence="12">2.7.7.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dnaG</name>
        <name evidence="16" type="ordered locus">Snas_1799</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13 14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13 14">Binds 1 zinc ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer. Interacts with DnaB.</text>
    </comment>
    <comment type="domain">
        <text evidence="12">Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the DnaG primase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.101" evidence="12"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017066.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1799"/>
    <dbReference type="EnsemblBacteria" id="ADD41495">
        <property type="protein sequence ID" value="ADD41495"/>
        <property type="gene ID" value="Snas_1799"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1799"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013501_3_1_11"/>
    <dbReference type="OMA" id="LMWPIRD"/>
    <dbReference type="OrthoDB" id="1071997at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00974">
        <property type="entry name" value="DNA_primase_DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019475">
        <property type="entry name" value="DNA_primase_DnaB-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006295">
        <property type="entry name" value="DNA_primase_DnaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013173">
        <property type="entry name" value="DNA_primase_DnaG_DnaB-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030846">
        <property type="entry name" value="DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002694">
        <property type="entry name" value="Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10410">
        <property type="entry name" value="DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08278">
        <property type="entry name" value="DnaG_DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01807">
        <property type="entry name" value="zf-CHC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002811">
        <property type="entry name" value="DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00766">
        <property type="entry name" value="DnaG_DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00400">
        <property type="entry name" value="ZnF_CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01391">
        <property type="entry name" value="dnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 12 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 12 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="15">
        <location>
            <begin position="265"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CHC2-type" evidence="12 14">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR002811-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ADD41495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="616" mass="66662" checksum="E5D74C327B9D44A0" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYF1</accession>
    <name>D3PYF1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycine cleavage T protein (Aminomethyl transferase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1822</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GcvT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017089.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1822"/>
    <dbReference type="EnsemblBacteria" id="ADD41518">
        <property type="protein sequence ID" value="ADD41518"/>
        <property type="gene ID" value="Snas_1822"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1822"/>
    <dbReference type="eggNOG" id="COG0404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_11_2_11"/>
    <dbReference type="OMA" id="GRTEIDH"/>
    <dbReference type="OrthoDB" id="282830at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032503">
        <property type="entry name" value="FAO_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16350">
        <property type="entry name" value="FAO_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAO" evidence="2">
        <location>
            <begin position="9"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="FAO_M" evidence="5">
        <location>
            <begin position="374"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T" evidence="3">
        <location>
            <begin position="430"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T_C" evidence="4">
        <location>
            <begin position="758"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="838" mass="90818" checksum="3EEF87FE776D09F6" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYK3</accession>
    <name>D3PYK3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3779</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019007.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3779"/>
    <dbReference type="EnsemblBacteria" id="ADD43436">
        <property type="protein sequence ID" value="ADD43436"/>
        <property type="gene ID" value="Snas_3779"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3779"/>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059164_1_0_11"/>
    <dbReference type="OMA" id="VNAAEFF"/>
    <dbReference type="OrthoDB" id="881796at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="202"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="30006" checksum="99779A804C65C6B0" modified="2010-04-20" version="1">MPALIIIAFVGIAAQLIDGGLGMGYGVISTSLLLLASLNPAAASASVHLAEIGTTLVSGASHWKFGNIDWNVVARIAVPGAVGAFIGAYALSSIPADNAKPWTSGILLLLGAYLLIRFSRGHAPVDPTKPPPRSKFLVPLGLVAGTVDATGGGGWGPIATPTLLASKRLDPKKIIGSVSAAEFAVAIAATAGFGFGSAIDGVVWPTVAALLIGGVIAAPIAAWLVRRLPTRILGVAVGGIIVGTNANTILGALEATAPIYYVSFAVLAVAWITALTLVLRTKALAPTEAETEPAEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYN6</accession>
    <name>D3PYN6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3813"/>
    <dbReference type="EnsemblBacteria" id="ADD43469">
        <property type="protein sequence ID" value="ADD43469"/>
        <property type="gene ID" value="Snas_3813"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3813"/>
    <dbReference type="eggNOG" id="COG3193">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103773_0_0_11"/>
    <dbReference type="OMA" id="YTAVSWN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="Haem_degrading"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="SSF143744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="207" mass="20360" checksum="65F64A2A9A5B28F4" modified="2010-04-20" version="1">MAAGPDPGSLESTKAQDFEKGTIMNIKSVKTRVIVGALGALAIVGGVTGVSAYTASPADANPATTVAAAGDEAVTETKTLSSEAALKAAKAALKEAEEQNQRVTVAIVDRAGNTIALVKGDGAGPQTQESAERKAFTAVSFGKATSELTEGATGDAPNISDIPGTLFLAGGVPVTADKAPIAGIGVGGAPSGDIDEKIAEAGLKAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ99</accession>
    <name>D3PZ99_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017144.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1877"/>
    <dbReference type="EnsemblBacteria" id="ADD41573">
        <property type="protein sequence ID" value="ADD41573"/>
        <property type="gene ID" value="Snas_1877"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1877"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="EIRFFEV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="291" mass="31382" checksum="57D45BABC3D590F0" modified="2010-04-20" version="1">MEIRQLEYFTAVADTGGFGRAATSLHIVQAAVSQQIRRLERELGVRLFDRSTRHVRLTDAGRRLLPEARAVLAAVERTRRLAADLAAGDSGLLRLGIGRAYDAGTYRVVAAATSAGSGPRVETHRTTLDERLSGVREGTLDAAVVRVQDSAPGLEFTPLWTDPLYVAAPTDVIPPTRDSVRLTDLSALPLRMAPRQNNPAFHDLILDACRRGGFDPVPGPAFTTLLETLHDIAGGEPSWTVFYPLDKPPAVPGVTLHRLSDVTTDVNLVTRPGPATPAIRHLLAAVRETTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZH0</accession>
    <name>D3PZH0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1948</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017215.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1948"/>
    <dbReference type="EnsemblBacteria" id="ADD41644">
        <property type="protein sequence ID" value="ADD41644"/>
        <property type="gene ID" value="Snas_1948"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1948"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="MSCFMGG"/>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="363"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="478"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="20"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="524" mass="54523" checksum="3766BDACA2CA663F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZI9</accession>
    <name>D3PZI9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">(R)-citramalate synthase</fullName>
            <ecNumber evidence="4">2.3.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_1967</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + H2O + pyruvate = (3R)-citramalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19045"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30934"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.182"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from pyruvate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the alpha-IPM synthase/homocitrate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.182" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017234.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1967"/>
    <dbReference type="EnsemblBacteria" id="ADD41663">
        <property type="protein sequence ID" value="ADD41663"/>
        <property type="gene ID" value="Snas_1967"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1967"/>
    <dbReference type="eggNOG" id="COG0119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022158_7_0_11"/>
    <dbReference type="OMA" id="NTMRMLV"/>
    <dbReference type="OrthoDB" id="840579at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00066"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043714">
        <property type="term" value="F:(R)-citramalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005675">
        <property type="entry name" value="Citramal_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43538">
        <property type="entry name" value="PTHR43538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00977">
        <property type="entry name" value="citramal_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="10">
        <location>
            <begin position="9"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD41663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="538" mass="57699" checksum="8596D54C8BD7795F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZM5</accession>
    <name>D3PZM5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3907</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43562">
        <property type="protein sequence ID" value="ADD43562"/>
        <property type="gene ID" value="Snas_3907"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3907"/>
    <dbReference type="eggNOG" id="ENOG502ZS6Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_813594_0_0_11"/>
    <dbReference type="OMA" id="NDIGEFT"/>
    <dbReference type="OrthoDB" id="839079at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="339" mass="37408" checksum="AE86098B0FF2A480" modified="2010-04-20" version="1">MRWMFGTRRLTNEQLTQLLRRLQRVEFGRWTQTDVTKAIGALGWDLQHGEVDVGMWRAETGYETGAAIIDRIPPTANVRSVNEFYAIELMVLRSAVRGEAGEQHRTNVFREALSTMLAEFGPPDVRGGDGGPWARWRDKELTVELHLRRFHGGVAMRLLATDALEQLEADSIRRGDVSGWTAYTRRPELPSEPAVNDIGEFTARLSGVLMDLAVDVPVVDTAGTIILRTSDWSARYALASVDGAIRVEASAAVKGQYREGLGYLAGLGYREPSGRVPNWSREFTDGGRDSTSAAAHMMVDALRAFGIDDLLDIVYDAFTADGERMYLPVLGIASADSMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZP7</accession>
    <name>D3PZP7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Uroporphyrinogen decarboxylase</fullName>
            <shortName evidence="8">UPD</shortName>
            <shortName evidence="8">URO-D</shortName>
            <ecNumber evidence="4 8 9">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hemE</name>
        <name evidence="13" type="ordered locus">Snas_3929</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>4 H(+) + uroporphyrinogen III = 4 CO2 + coproporphyrinogen III</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8 9">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="4 8 9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019155.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3929"/>
    <dbReference type="EnsemblBacteria" id="ADD43584">
        <property type="protein sequence ID" value="ADD43584"/>
        <property type="gene ID" value="Snas_3929"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3929"/>
    <dbReference type="eggNOG" id="COG0407">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040933_0_1_11"/>
    <dbReference type="OMA" id="LWLMRQA"/>
    <dbReference type="OrthoDB" id="1104410at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00907">
        <property type="entry name" value="UROD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8 9" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen_deCOase" evidence="11">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Uroporphyrinogen_deCOase" evidence="12">
        <location>
            <begin position="141"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="29"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD43584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="345" mass="36591" checksum="F4A41A6B0840369B" modified="2010-04-20" version="1">MTTEDVSQSPFLRACRGEETPRTPVWFMRQAGRSLPEYRALRADTPMLTACRTPDMIREITMQPVRRHGVDAAIFFSDIVVPLAAVGVDVDIVAGTGPVVGQPIRDMAGVEALRDLTPEDVPYITEAVGMLREELGATPLIGFAGAPFTLASYLVEGGPSRTYAKTKALMHGAPDVWHALCGRLAGITASFLKVQIDAGANAVQLFDSWAGALSAADYGMFVAPHSAAVLSAVARPGVPRIHFGVGAGHLLAAMGEVGADVVGVDWRIPLTEAAGLVGDRALQGNLDPTTLFAPEDVLAHEVRRVLAEGKAAKGHIFNLGHGVLPETDADALTKTVEYVHRFSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZS0</accession>
    <name>D3PZS0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43607">
        <property type="protein sequence ID" value="ADD43607"/>
        <property type="gene ID" value="Snas_3955"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3955"/>
    <dbReference type="HOGENOM" id="CLU_1488184_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="181" mass="20413" checksum="94B140B23A0821E4" modified="2010-04-20" version="1">MELRRSLNPMPFELRTKRDVEAKQMLLPALAALLVGISMALILDLSTWPSWALLGCVALVIVFSLFMYLRFGGRPVLAADTERLWIRIGAATFVGLSWSEVDNLRLTTRDVHKYLLWDAPTAVDELQASPKLWKTTNGTRVAFDTPFAIGFTNKDRDRRSTINELRKLAPSGTEFRTVTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZV9</accession>
    <name>D3PZV9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3994"/>
    <dbReference type="EnsemblBacteria" id="ADD43646">
        <property type="protein sequence ID" value="ADD43646"/>
        <property type="gene ID" value="Snas_3994"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3994"/>
    <dbReference type="HOGENOM" id="CLU_198864_2_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="49" mass="4852" checksum="853BB7EFF5B86D1E" modified="2010-04-20" version="1">MPILMIGVGGFLIGGVVSAAKAKKPLPAIVLGVLAAVAIAGGILWLWPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0A3</accession>
    <name>D3Q0A3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3">5.3.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_6006</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6006"/>
    <dbReference type="EnsemblBacteria" id="ADD45632">
        <property type="protein sequence ID" value="ADD45632"/>
        <property type="gene ID" value="Snas_6006"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6006"/>
    <dbReference type="eggNOG" id="COG1482">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026967_1_1_11"/>
    <dbReference type="OMA" id="DIGLFCG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016305">
        <property type="entry name" value="Mannose-6-P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309">
        <property type="entry name" value="PTHR10309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01238">
        <property type="entry name" value="PMI_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001480">
        <property type="entry name" value="Mannose-6-phosphate_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00714">
        <property type="entry name" value="MAN6PISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00218">
        <property type="entry name" value="manA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="402" mass="42858" checksum="572DDB883A33A795" modified="2010-04-20" version="1">MVTVELLNGAIRPYAWGSRTAIAALQGRSMPSSTPEAELWFGAHPADPSRLPDGRDLNEAIAKAPEALLGAETVAEFGARLPYLLKVLAAEQPLSLQAHPDADQAIEGFTREDEAGVPLGTPERNYVDAFHKPELLCAVSEFEALCGFRDPQLSAEVIETLGVPGLESIVALLRQDDAAQGLREAVTTLLTLPADHREELVRQATLSAERLADTDSPHAFDFALVADLGKRYPSDAGTIVALLLHHITLQPGQAIYMPAGNLHAYLRGVGVELMAASDNVLRGGLTGKHVDVPELLRVLRFEVLGDPISPAREAGGGIVDWPVPSREFRLSRLRLEADSGQRTLPVNGPSIILCWSGQIRLDDGVSPITLQPGQAAFAPADTPTIYASGFGDSYCAGLGTGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0E8</accession>
    <name>D3Q0E8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative cytoplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0091"/>
    <dbReference type="EnsemblBacteria" id="ADD39812">
        <property type="protein sequence ID" value="ADD39812"/>
        <property type="gene ID" value="Snas_0091"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0091"/>
    <dbReference type="eggNOG" id="COG5495">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055635_0_0_11"/>
    <dbReference type="OMA" id="GEPEWIA"/>
    <dbReference type="OrthoDB" id="1194694at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018931">
        <property type="entry name" value="DUF2520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019665">
        <property type="entry name" value="OxRdtase/DH_put_Rossmann_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037108">
        <property type="entry name" value="TM1727-like_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10728">
        <property type="entry name" value="DUF2520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10727">
        <property type="entry name" value="Rossmann-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rossmann-like" evidence="1">
        <location>
            <begin position="11"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2520" evidence="2">
        <location>
            <begin position="151"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="308" mass="31957" checksum="9D4A722FABB76F9E" modified="2010-04-20" version="1">MAMSPTGASGPHQESRLDVGIISAGRVGSVLGAALARAGHHIVATSAVSDASRDRARRLLPDAAVLSPDEVAERAGLLLLAVPDDELAQVVSGLATAGHFQPGQLVAHVSGAHGIEVLRPAVSAGALPLALHPVMTFTGRPEDLDRLDGVSFGVTADETMRMVGEALVVEMGGEPEFIPEQLRALYHAGLCHGANHMTTLINEAVDILRECGVMHPERMLGPLLSASLDNTLRLGDNALTGPIVRGDTGTVASHLDALSRALPDSVAAYRAMARRTADRAISHKRLSVAAAEPLLDVLSGPDGEGGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0P7</accession>
    <name>D3Q0P7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017354.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2089"/>
    <dbReference type="EnsemblBacteria" id="ADD41783">
        <property type="protein sequence ID" value="ADD41783"/>
        <property type="gene ID" value="Snas_2089"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2089"/>
    <dbReference type="HOGENOM" id="CLU_2847699_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="1">
        <location>
            <begin position="10"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="65" mass="7011" checksum="8662293E17B543F1" modified="2010-04-20" version="1">MKTGIKLTDGWTKSSHSGHAGACVIARIKHNQWQFGDSKYGRLYNGPTPILTADAALINSIKNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0S9</accession>
    <name>D3Q0S9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmF</name>
        <name evidence="7" type="ordered locus">Snas_2121</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2121"/>
    <dbReference type="EnsemblBacteria" id="ADD41815">
        <property type="protein sequence ID" value="ADD41815"/>
        <property type="gene ID" value="Snas_2121"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2121"/>
    <dbReference type="eggNOG" id="COG0333">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129084_1_1_11"/>
    <dbReference type="OMA" id="HRACRHC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_L32p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044957">
        <property type="entry name" value="Ribosomal_L32p_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35534">
        <property type="entry name" value="PTHR35534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048146" description="50S ribosomal protein L32" evidence="6">
        <location>
            <begin position="18"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="57" mass="6325" checksum="CA5E671493966B6D" modified="2010-04-20" version="1">MAVPKRRMSRSNTRSRRSNWKATAPALSTCSQCRSQTLPHTACGVCGTYKGRQILDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0T4</accession>
    <name>D3Q0T4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4032</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019255.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4032"/>
    <dbReference type="EnsemblBacteria" id="ADD43684">
        <property type="protein sequence ID" value="ADD43684"/>
        <property type="gene ID" value="Snas_4032"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4032"/>
    <dbReference type="eggNOG" id="COG2380">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069565_0_0_11"/>
    <dbReference type="OMA" id="HKDPRAP"/>
    <dbReference type="OrthoDB" id="1633344at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="33072" checksum="E8176843F7240808" modified="2010-04-20" version="1">MRISVSAWDPGYADTGEKTGEAAQAKMDLDVEVPAVKWEPIGSDVPAPPRVLLVDGVRRLDARVDIAVEGQPPVPGICASYGAGVVECDPGGGSTATIPVSRIERGLFSAVPDAGLTAGRTAAYVAHRSRASEPGDLLNAVQDRLTALEIEVATEAEPGRDDLLVIDGALRRRTHLPRAVGFIKSHQRRYLPDHLSSIIDKLEPGQRTPVFVLGTSWQRHTWYLRLPGGGDGSWAGIARLEAADDLTIAEVVALADSASAVLPRLASVAHKDPRAPQNLTPIAGLERRLRAKLGDPRLLLRGLRTGARAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q155</accession>
    <name>D3Q155_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019376.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4154"/>
    <dbReference type="EnsemblBacteria" id="ADD43805">
        <property type="protein sequence ID" value="ADD43805"/>
        <property type="gene ID" value="Snas_4154"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4154"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030487_0_0_11"/>
    <dbReference type="OrthoDB" id="1951208at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032774">
        <property type="entry name" value="WG_beta_rep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14903">
        <property type="entry name" value="WG_beta_rep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="35595" checksum="F238F813F795F6F4" modified="2010-04-20" version="1">MLSAIGAETDNRLNTATDEADRSRLLGVRSVALRALGERDSAEADAKSSLKHAENVGTDLLLAPARARLAQTLRLRQDHTGADRLYALAEAGELPRRFLGRVRACAALSCIAQRRLTEALLHLERASEYTSDETTTASIAPALEHVYRLAMEGFGPPPRSWEERAQHPAPRRYQEPRSGKWGYLGSDRRPVISPTFAEAGEFRGGIAAVRERAWGAIDTSGNLLVPFLYDGVSTQVPDGRTVVGFVDGVAVIELRGGKGLVDRAGTLILPPHHRDIVVHPAGYATDTGAATWGARDRNGEEIIPQRFSRADVLRRLDTMVNIDEGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1J9</accession>
    <name>D3Q1J9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative glycine-rich surface protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0126</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015418.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0126"/>
    <dbReference type="EnsemblBacteria" id="ADD39847">
        <property type="protein sequence ID" value="ADD39847"/>
        <property type="gene ID" value="Snas_0126"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0126"/>
    <dbReference type="eggNOG" id="ENOG5033GQX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_787349_0_0_11"/>
    <dbReference type="OMA" id="NIRRCLL"/>
    <dbReference type="OrthoDB" id="1442276at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005528">
        <property type="entry name" value="ChpA-H"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03777">
        <property type="entry name" value="ChpA-C"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51884">
        <property type="entry name" value="CHAPLIN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0034">Amyloid</keyword>
    <keyword evidence="1" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048549" evidence="4">
        <location>
            <begin position="30"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Chaplin" evidence="5">
        <location>
            <begin position="39"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Chaplin" evidence="5">
        <location>
            <begin position="96"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Chaplin" evidence="5">
        <location>
            <begin position="308"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="352" mass="33425" checksum="A05E736E4F30B271" modified="2010-04-20" version="1">MTKTWARRTVQASAIAAGVLLVSAGAAQAYGSDANTTGNIGVGTGNQAMAPVQAPIDICGNATSVLGVANAGCHGGSNATMTESAHGGSDLTSTGNMGVGNGNQVYAPIQAPISVCGNSTSVAGSATSGCKGGSDATLNNGHGAPDATTTGNLGALTGNQAILPVQAPVDVSGNATTVGGHSVAGSHGGSNALAWAGGHHKAAEALPGVPGGLPTAGVTNVPVGQVTGALPTNDLGNKLTSGGVDGVTGNLPTAGVTDGLPTAGVTDGITGKKPVKDVTKKATKVTKPATESGRVAEHGGADLTSTGNLGVGNGNQVYAPIQIPVDISGNSIAVGGVSTAGSHGGSNATQNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1L0</accession>
    <name>D3Q1L0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Replicative DNA helicase</fullName>
            <ecNumber evidence="3 12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Snas_0137</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 12"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015429.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0137"/>
    <dbReference type="EnsemblBacteria" id="ADD39858">
        <property type="protein sequence ID" value="ADD39858"/>
        <property type="gene ID" value="Snas_0137"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0137"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005373_0_0_11"/>
    <dbReference type="OMA" id="IEFHARI"/>
    <dbReference type="OrthoDB" id="1709134at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00984">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007692">
        <property type="entry name" value="DNA_helicase_DnaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00665">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="11 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 12 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 12" id="KW-0639">Primosome</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="14">
        <location>
            <begin position="211"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD39858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="474" mass="51887" checksum="7DC654EC8CD775CB" modified="2010-04-20" version="1">MDHDTYANRKGGAQQSRAGDYPDEPPPEEGGHEFERTPPQDVMAERSVLGGMLLSKDAIADVVEILKTNDFYKPAHATIFDVICDKYARGEPADAVTMVAALNDLGELGKVGGAPYLHTLISSVPTAANAAYYARIVSERAILRRLIEAGTRIVQLGYGTAAGGGRDVDDLVDLAQQAVYDVTERRVSEDFAVLSELLQPTLDEIEAVGESAGAMTGVPTGFADLDRLLNGLQPGQLIIVAGRPGAGKSTAAMDFIRHAALHHQQAAAMFSLEMSKVEIVMRVLSAETRVPLHVLRSGQLSDDDWTRLARRMGEISEAPMFVDDTPSMTLMEIRAKARRLKQRHNLKLIVVDYLQLMSSPKRVESRQQEVSEISRGMKLLAKEVECPVIAVAQLNRGPEQRTDKRPQLSDLRESGSLEQDADVVILLHRDDYYDKESPRAGEADMIVAKHRNGATDTITVAAQLHLSRFVDMAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q208</accession>
    <name>D3Q208_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome maturation factor RimM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rimM</name>
        <name evidence="5" type="ordered locus">Snas_2183</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Binds ribosomal protein S19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">The PRC barrel domain binds ribosomal protein S19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RimM family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017446.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2183"/>
    <dbReference type="EnsemblBacteria" id="ADD41875">
        <property type="protein sequence ID" value="ADD41875"/>
        <property type="gene ID" value="Snas_2183"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2183"/>
    <dbReference type="eggNOG" id="COG0806">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077636_0_0_11"/>
    <dbReference type="OMA" id="DEFYHAD"/>
    <dbReference type="OrthoDB" id="1497415at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00014">
        <property type="entry name" value="Ribosome_mat_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="16S_RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02273">
        <property type="entry name" value="16S_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="RimM" evidence="3">
        <location>
            <begin position="4"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="PRC" evidence="4">
        <location>
            <begin position="93"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="169" mass="18372" checksum="5B98F20E30B355F7" modified="2010-04-20" version="1">MKLVVGRIVRSHGVRGDLIVEVRTDEPEQRFAGGSVLHTDPPRFGPVTVERVRWYQERLLLTLEGVADRDAAEAMRGVALTVDSEDVEVPEDPDEFRDLDLVGLSVVEESGAEIGTVVRVEHAPAHDLLVVDRPGANQALIPFIQAMVPTVDVAGGRIVVTLPEGLLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q217</accession>
    <name>D3Q217_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mg chelatase, subunit ChlI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2192</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017455.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2192"/>
    <dbReference type="EnsemblBacteria" id="ADD41884">
        <property type="protein sequence ID" value="ADD41884"/>
        <property type="gene ID" value="Snas_2192"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2192"/>
    <dbReference type="eggNOG" id="COG0606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026145_1_0_11"/>
    <dbReference type="OMA" id="STNPCPC"/>
    <dbReference type="OrthoDB" id="581802at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00368">
        <property type="entry name" value="TIGR00368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="211"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="510" mass="54339" checksum="FB0B9780DC3A1C51" modified="2010-04-20" version="1">MAYSRSQTVCLTGFQGHPVTVEAHIAKGRPALVVTGLPDIALEQSKVRIFSAFTNSGLEWPDTYTVVNLLPASVRKSGSVCDLAIAAAILAAGYTVPRDRLEGTVLLGELGLDGQLQPVRGVLPCLLAAERAGADTAIVPLRNLAEASLVSRLKCLGANHLSEVVAFLRGEESLSATAPVVPEEPAAELPDMADVVGQETARRGLEVAAAGGHHLFLLGPPGAGKTMLAERLPSILPPLDEAAALETTALHSIAGTLKGTHPRLLRRPPYSAPHHSVTMPAMVGGGTPLRPGAISMAHNGVLFLDECPEARRDVLDALRQPLERGEILISRARSSARFPARIQLVLAANPCPCAASSTESCTCPAPRRHRYLSRLSGPLMDRVDIRIEVAPVPMSAMLSADAVPESSEVIAARVAEARRAARERWSDAEQEWRTNSEVPGPRLRAKPWRLPTSVTKTADWLVETGQLTGRGYDRTLRMAWTLADLAGRDRPDSGDIAEAAGLRVGWLPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q273</accession>
    <name>D3Q273_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2250</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017511.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2250"/>
    <dbReference type="EnsemblBacteria" id="ADD41940">
        <property type="protein sequence ID" value="ADD41940"/>
        <property type="gene ID" value="Snas_2250"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2250"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_0_11"/>
    <dbReference type="OMA" id="AYVEQSF"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="144"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="217" mass="23525" checksum="D9005A289ADF843A" modified="2010-04-20" version="1">MRIVIAEDDALLREGLVLVLRGEGFEVAAAVGDPTAFAAAVTEHRPDIAVLDVRMPPSHTDEGIRAAVAARREHPDLAVLVLSAYVEQSFATDLLADGAKSVGYLLKERVGRVDTFVSALRRVAEGGTAIDPEVVAQLFARQRADDPLSRLSPREREVLAVMAEGLGNAAIAKRLFITDNAVHKHIRSIFAKLELAPDDETDRRVAAVLRYLDGTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2C2</accession>
    <name>D3Q2C2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MDMPI_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019426.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4205"/>
    <dbReference type="EnsemblBacteria" id="ADD43855">
        <property type="protein sequence ID" value="ADD43855"/>
        <property type="gene ID" value="Snas_4205"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4205"/>
    <dbReference type="eggNOG" id="COG1576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051661_2_0_11"/>
    <dbReference type="OMA" id="APKAREM"/>
    <dbReference type="OrthoDB" id="2055578at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017520">
        <property type="entry name" value="CHP03086"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03086">
        <property type="entry name" value="TIGR03086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="1">
        <location>
            <begin position="13"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="20309" checksum="2C2D4C294280FE23" modified="2010-04-20" version="1">MRDLYAKAAALTVPLVGNITDEQLAGPTPCAEFDVRALLNHLYEVVVAFQRTARFEPMDFDDSREHITGDDWRARFATEVAAVSREWSRPEALEGEGSVPGFPRELLARLPVFDLTVHGWDLARATGQEFRADPALVEAVYEIALGFAETARQAGQVGEPVAVPETAPVIDRLVGLVGRDPAWKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2G0</accession>
    <name>D3Q2G0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4244</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4244"/>
    <dbReference type="EnsemblBacteria" id="ADD43893">
        <property type="protein sequence ID" value="ADD43893"/>
        <property type="gene ID" value="Snas_4244"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4244"/>
    <dbReference type="HOGENOM" id="CLU_3222358_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="44" mass="5123" checksum="EC7E8F75CCE28A36" modified="2010-04-20" version="1">MNTKKTPARRTRYARPTVTLLGDAVKLTNGGQYNDTHDSRQYYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2I6</accession>
    <name>D3Q2I6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">5'-Nucleotidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4270</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019490.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4270"/>
    <dbReference type="EnsemblBacteria" id="ADD43919">
        <property type="protein sequence ID" value="ADD43919"/>
        <property type="gene ID" value="Snas_4270"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4270"/>
    <dbReference type="eggNOG" id="COG0737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005854_5_2_11"/>
    <dbReference type="OMA" id="VQPFTNM"/>
    <dbReference type="OrthoDB" id="1884225at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005126349" evidence="1">
        <location>
            <begin position="32"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="3">
        <location>
            <begin position="41"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="4">
        <location>
            <begin position="382"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="569"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="588" mass="62764" checksum="058F13B5ABB34139" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Q4</accession>
    <name>D3Q2Q4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021376.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6182"/>
    <dbReference type="EnsemblBacteria" id="ADD45805">
        <property type="protein sequence ID" value="ADD45805"/>
        <property type="gene ID" value="Snas_6182"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6182"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108054_3_0_11"/>
    <dbReference type="OMA" id="VDWDLYP"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="3"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="123" mass="13425" checksum="14056B2273A84AE1" modified="2010-04-20" version="1">MLRIGSTVLGVSDVKRAVDFWTKALDYVPRDDDFDDTWAVLVPAEGLGAALSLGLSDTPAQDKPRVHLDLYAGDAEDQDAEVERLIALGASRVDWDSYPSDPDFVVLADPDGNRFCVIETDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q307</accession>
    <name>D3Q307_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015548.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0259"/>
    <dbReference type="EnsemblBacteria" id="ADD39977">
        <property type="protein sequence ID" value="ADD39977"/>
        <property type="gene ID" value="Snas_0259"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0259"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_11"/>
    <dbReference type="OMA" id="IREDMSI"/>
    <dbReference type="OrthoDB" id="1180629at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="357" mass="40312" checksum="5ED6017D69A9C8A0" modified="2010-04-20" version="1">MSVALITGSAGLIGSEAVRHFAKLGFTVAGIDNDMRAYFYGSDGSTAWQVEELKRELGASYEHHSVDIRDRDGLDKLFKHYGSDLAVIIHCASQPSHDWAAKEPFTDFDINATGTLNLLEYTRKYAIDAPFIFCSTNKVYGDTPNRLPLIEKDTRWEIDPSHPYVDGIREDMSIDNTLHSIFGASKVASDIMVQEYGRYFDMKTAVFRGGTLTGPAHSAAELHGFLGYVMRCVMERRNYNIYGYKGKQVRDAIHSHDVVTAFEAFYRAPRVAEIYNLGGGRASNISVLESFTVAEEITGEKAQTTYVDQNRVGDHIWWISSMARFQEHYPDWKMSHDVNSIMRGIYEANVDRWVPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3C0</accession>
    <name>D3Q3C0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017532.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2272"/>
    <dbReference type="EnsemblBacteria" id="ADD41961">
        <property type="protein sequence ID" value="ADD41961"/>
        <property type="gene ID" value="Snas_2272"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2272"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_796722_0_0_11"/>
    <dbReference type="OrthoDB" id="1456605at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="348" mass="37190" checksum="92379C3BA3203C51" modified="2010-04-20" version="1">MNNEFREHLTELANKMNGIDMYDNVLTASRKRTIRRTVLAAGAAVVMVGGLVGVGLTVLPSADAEPPPGDDKKGEQSQGIPGQLYYPDDDGNYTIVEDGENVGNPWAKDSTISHDGKMAAWLEESSGFLIADDAEGTVYGQFPPGKKDLGVDNPCVRPTWSPIDDQLLYAVEIDGDATKLQIQIRDVSTSELTASFPADGACNFRWAADGTGLVAQKGYQGDMVAMDVDGSGRNEFSVESQGAEVSLFSVSAGTKEICVAQGFQHSDDEPYSRTCNTTVDPETGQVGGSVSGGGGVDAVHYTADGNTLIRKSTENGMSVTLYDAKRGVLAEYKEPEEYADYRLAQYLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3V4</accession>
    <name>D3Q3V4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glucose sorbosone dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4374</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019592.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44021">
        <property type="protein sequence ID" value="ADD44021"/>
        <property type="gene ID" value="Snas_4374"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4374"/>
    <dbReference type="eggNOG" id="COG2133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012253_0_0_11"/>
    <dbReference type="OMA" id="IWSKGHR"/>
    <dbReference type="OrthoDB" id="567019at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049516" evidence="2">
        <location>
            <begin position="26"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="GSDH" evidence="3">
        <location>
            <begin position="46"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="343" mass="36280" checksum="10FA422892973502" modified="2010-04-20" version="1">MKRPWIAVSIVTALVGAGVAGVASADTETAEAGFDFGNGETVAEGLELPWGMDFLPDGSALFAQRDTAEIKQVKPGGEAEVVATLDEVQPNGEGGLLGLAVSPTYDEDKFVYVYYTTGEDNRVARLTLDNPAPEVIIDGIPRASIHNGGRLEFGPDGKLYATTGDASNGDNSQDPENLGGKILRVNPDGSVPDDNPTKGSPVYTLGHRNVQGIAWTKEGQAFASELGQNTWDEVNKIEAGKNYGWPEVEGEGGEPEYVDPIVTWATSEASPSGAEIVGDTMFVAALRGERLWLVPHGGGDPTAVLEGEVGRIRTVELGPDGYLWIATANGSDDKILRFPPEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Y3</accession>
    <name>D3Q3Y3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pirin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4404</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019621.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4404"/>
    <dbReference type="EnsemblBacteria" id="ADD44050">
        <property type="protein sequence ID" value="ADD44050"/>
        <property type="gene ID" value="Snas_4404"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4404"/>
    <dbReference type="eggNOG" id="COG1741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045717_5_1_11"/>
    <dbReference type="OMA" id="TPWHPHR"/>
    <dbReference type="OrthoDB" id="833478at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PTHR13903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin" evidence="3">
        <location>
            <begin position="42"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin_C" evidence="4">
        <location>
            <begin position="201"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="320" mass="33763" checksum="2E02B9BCBE1FF54F" modified="2010-04-20" version="1">MPAVTVSDILVLPRVTTAADAAQRPVSRVTDSIRTLEGAGFPVRRPFPGPSGADTDPFLLLDHMLAAYEPQEAKGAPWHPHRGFETVTYLMDGTFVHHDSNGGGGVISDGDTQWMTAGSGILHDELPSEELVMKGGYFNGIQLWVNLPKAAKWAKPRYQDIKGGKLKLLSSADGGGLVRLIAGDLGEHSGPGVTYTPITLAHVSLSPGARLSVPWSPEFSAMAYVLSGDGFAGAENRPLGDAKLATFGPGDVVTITAGKQQNGRTGQYEVLLLGGAPLREPVARYGPFVMNTRSEIIQAVEDFQAGRMGSVPATHLGGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q426</accession>
    <name>D3Q426_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021482.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6291"/>
    <dbReference type="EnsemblBacteria" id="ADD45911">
        <property type="protein sequence ID" value="ADD45911"/>
        <property type="gene ID" value="Snas_6291"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6291"/>
    <dbReference type="eggNOG" id="COG4312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066898_1_1_11"/>
    <dbReference type="OMA" id="LIAYFHM"/>
    <dbReference type="OrthoDB" id="1567592at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010296">
        <property type="entry name" value="DUF899_thioredox"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05988">
        <property type="entry name" value="DUF899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="29103" checksum="BA6AC4DAA757CC3A" modified="2010-04-20" version="1">MTESIRNPVPDVVDRETWKTQVNALRAREKAHTREGDAIAAARRRLPVVEVDATTTLTGPGGKVTLLDTFEGRNQLIAYFHMWFTGQPAAEQCEGCTLFNGQVRELSYLHSRDITYATFCQGPYDESVRYRDFMGWDVPWYSAAESADTLMAGRGPILLSCYLRDGDRVFETYWTENRGVEVMDNSYALMDLTVFGRQEGWEDSPDGWPQPWRWEDGSNHASNDGRPSAQWSRLRAGRSDDLGNSGQSPDSGGGCCSHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q486</accession>
    <name>D3Q486_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_S9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021542.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6355"/>
    <dbReference type="EnsemblBacteria" id="ADD45971">
        <property type="protein sequence ID" value="ADD45971"/>
        <property type="gene ID" value="Snas_6355"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6355"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057522_0_0_11"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="163"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="337" mass="36532" checksum="164F8E960235C341" modified="2010-04-20" version="1">MVKPVEDVVPDVAPAAAAPKRRRWLRYAAATLAVILLATPGVSWYFAGEVINVQHNPPEFSLPVTDVTDTEVTLPTEEETVRPGTWGLQWADGRAVLGEVVRSNAETVTREIDDIVYGELREGTATRIDGWTYGEDPKQAHGIDFDEVDVPTELGDAPASPDGYHHLGDSEWRDVEAAIDYALDKGAKNVVLHGWSMGGAVTMTTLRRMEAPDRVAGIILDSPVLDWNSTLDKQGGQRFLPAPITGLAKSFAEWRAGFDLADLDQRAFAPDLETPTLLFADTADETVEVSATLDFAAAAPEDLLTLVKTSSGHTSSWNEDPGAYSSQLEKFLANLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4B2</accession>
    <name>D3Q4B2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="11">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cysS</name>
        <name evidence="13" type="ordered locus">Snas_0354</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="11"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015643.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0354"/>
    <dbReference type="EnsemblBacteria" id="ADD40072">
        <property type="protein sequence ID" value="ADD40072"/>
        <property type="gene ID" value="Snas_0354"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0354"/>
    <dbReference type="eggNOG" id="COG0215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013528_0_1_11"/>
    <dbReference type="OMA" id="AKYWMHN"/>
    <dbReference type="OrthoDB" id="952207at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00840">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DALR_2" evidence="12">
        <location>
            <begin position="346"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="11">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="11">
        <location>
            <begin position="268"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD40072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="480" mass="53000" checksum="00CB1DEA5A568207" modified="2010-04-20" version="1">MSLRLYDTGTRKVRDFVPRVPGKVSIYLCGLTLQGPPHIGHLRNGVNYDIMCSWFQHRGLDVTYVRNVTDIEDKVLAKSREQDRPWWAISFENERRLAADYEALGVRPPTYEPRATGHVPEMMDLIAELINKGHAYAPGNGDVYFSVESYPEYGALSHRKPEDMLCPDDGDESVKRDPRDFALWKAAKPGEPADSSWNTPYGRGRPGWHLECSAMSRRYLGDAFDIHGGGTDLMFPHHENELAQSRAAGLDFTNFWVHNNMVNLSGTKMSKSLGNVLSVEALGERGFRPVEIRYYLAAPHYRSVIDYSDAILTESATSYRRLENFVSRAAERFGHDATEGGALCADFTAALDDDFGTPAAFAAIHEVTREGNAALDSSDDAAARGAAASVRAMLGVLNLDPLSRQWTETGGDDLTPVVDSLVNLVLEQRQQARKNKDYATADAIRDQLSRAGLVIEDGPQGSRWSLARADHATGAEAHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4D0</accession>
    <name>D3Q4D0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5'-deoxynucleotidase</fullName>
            <ecNumber evidence="5">3.1.3.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0373</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18274"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.1.3.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.89" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0373"/>
    <dbReference type="EnsemblBacteria" id="ADD40090">
        <property type="protein sequence ID" value="ADD40090"/>
        <property type="gene ID" value="Snas_0373"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0373"/>
    <dbReference type="eggNOG" id="COG1896">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039453_4_0_11"/>
    <dbReference type="OMA" id="VEYREQG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002953">
        <property type="term" value="F:5'-deoxynucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039356">
        <property type="entry name" value="YfbR/HDDC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845">
        <property type="entry name" value="PTHR11845"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13023">
        <property type="entry name" value="HD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDc" evidence="6">
        <location>
            <begin position="37"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="196" mass="21235" checksum="6ABBC7215F0E26CD" modified="2010-04-20" version="1">MKGQGVSELAGEAGYLLEIGLLKRTRRTGWWIAGIRDPESIAEHSWRTAITGMIIASHEGADPARTSMLCSLHDTPETRIGDIPKIGKHYLKATAPDTIAADQTAKCSDQAGQVIRDAIAEFEAGQTPEALCAKDADKLECLIQAVEYQHQGVSTVTRWIESSLAALKTDTARGLADEILKANPLAWEQTRRPSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4F7</accession>
    <name>D3Q4F7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WD40 domain protein beta Propeller</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0400"/>
    <dbReference type="EnsemblBacteria" id="ADD40117">
        <property type="protein sequence ID" value="ADD40117"/>
        <property type="gene ID" value="Snas_0400"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0400"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_899898_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049534" evidence="1">
        <location>
            <begin position="35"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="309" mass="33324" checksum="3A13C0577D7C23A7" modified="2010-04-20" version="1">MRSRSPNVIRIARSTAGVALLLATATLGSCTDQAATVDESCDVNDRGHWAIAYTKQEDTAVKGVYWLVDGEHKPLNKDKDIQAQDPSLSPDGRKVLFEGFHGDGGKYVNKKLIMNTDGSGLKIFGEGISTPVWSPNGKRLAYRDTDRNTIMVSNPDGTDEREIAEDAASNPVWSADGEKLAWIPNGANAVRWAEPEGKKSGMAQMLGEQAITVAWQPDGESVVVSLVKGDDAHLYRLNLSDNKEPELLAEDATAPFALPDGTIGARVDKRGDGDYNQYVSVDPKTGKSEDLAKIPGQHPSVIACHGVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4H4</accession>
    <name>D3Q4H4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M1 membrane alanine aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0417</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015705.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0417"/>
    <dbReference type="EnsemblBacteria" id="ADD40134">
        <property type="protein sequence ID" value="ADD40134"/>
        <property type="gene ID" value="Snas_0417"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0417"/>
    <dbReference type="eggNOG" id="COG0308">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015077_1_0_11"/>
    <dbReference type="OMA" id="GGMEYAM"/>
    <dbReference type="OrthoDB" id="771837at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048860" evidence="1">
        <location>
            <begin position="25"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="2">
        <location>
            <begin position="308"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="446" mass="48429" checksum="5414CEB442ABA40D" modified="2010-04-20" version="1">MKKRFLLLAGVLAASVAAVGPAQAAEPDEPVTPQDAKYLLSLDSDATGANWSGTQTVTFRNKSDRTMDTLWIRLWGNGRGGCDDRAVSIEPRFGGELGAETVDCTAVPIELTRPVPAGRTGMVSVDVDIAVPEETYRFGRAGDYRFIGNAIPVLAVHDGTGELPPFTSFGESFYTLESDFLVTLDHPNAVKVPATGRSIAEVKHGKNTTTVIKANNVRDFAWAAGPFAKVDTVSATGAKLRTWYPGDIDKAKAEEVTGWVKEGMDTFDAAYGEYPYSEMDTVIGDWEGFAGMEYPGFILTEPAKVPAVHEAGHQWFYGLVGNDQYNDPWLDESVTQYMTNTITGVPGYCATAPFWFSDGMRIDAGMDYYNEHIEDEYAPAIYGDGACMLAELETTIGKPAMDEALRTAVAEFSGGVITSDELRGIFAEVSGQDLSAFWERWRNTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4I1</accession>
    <name>D3Q4I1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0424"/>
    <dbReference type="EnsemblBacteria" id="ADD40141">
        <property type="protein sequence ID" value="ADD40141"/>
        <property type="gene ID" value="Snas_0424"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0424"/>
    <dbReference type="HOGENOM" id="CLU_1936841_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="130" mass="13745" checksum="F8160042E8BF6662" modified="2010-04-20" version="1">MNPSTRFTVEVTAHDEVSTEVLTRQLRIDLRALGPLSLEPVFASMPVSPDDDPLLPPLRSGSASHQGVIAATGALSDPAVKNLFELLVAFVNRTGVGSVTVRRGEDAVSVAGASHEDSSRELSELEKLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4L1</accession>
    <name>D3Q4L1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0456</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015742.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0456"/>
    <dbReference type="EnsemblBacteria" id="ADD40171">
        <property type="protein sequence ID" value="ADD40171"/>
        <property type="gene ID" value="Snas_0456"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0456"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="FGISHAV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03793">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00740">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51178">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="7">
        <location>
            <begin position="379"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="246"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="307"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="344"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="363"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="395"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="426"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="467"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="490" mass="53161" checksum="EAE337D6B102FCDE" modified="2010-04-20" version="1">MGEVWRGDDTRLNRPVAVKLLHSSLSENKQFRERFAREATLVAGLKGQHVATVYDYGEEDSSGAVRSYLVMELVDGRPLSEILDERGPLPVPETVRVIGQAAEGLRAAHEAGIIHRDVKPANILLTPDGSVKLIDFGIAHLRGKAGLTDSGIFLGTLAYVCPDQIADEEPTPSTDIYSLGVVAYECLTGSPPFASDVPAAVLNSHLYEPPPPLPEEIPAHVSHAILMALRKRPEHRWQTMAEFAQGIRNPDTPAPPPEPTSTPDPETPARAPKRKLQWLIQGAMAVVIAILSILLWQLPWQIPGFPGHGDNGGNGGQQFPGIVAESDEPAQDDTPAPGQSETPDVDDKSNKNSSDDSTPESAEEADTPTPANDNDDGGNDETASVPRLKGKNPNDATALLNQHGFHNHNPVRTDPQDGKKQCVVYRQSPRPNTTASTDTTITYYYRADPKTSCDGNDTQSDDDPPPNPHSTWTPHPPRPSTTPHTRLRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4N0</accession>
    <name>D3Q4N0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PE-PPE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015761.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0475"/>
    <dbReference type="EnsemblBacteria" id="ADD40190">
        <property type="protein sequence ID" value="ADD40190"/>
        <property type="gene ID" value="Snas_0475"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0475"/>
    <dbReference type="eggNOG" id="ENOG5033U8W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1106588_0_0_11"/>
    <dbReference type="OMA" id="VERHCIA"/>
    <dbReference type="OrthoDB" id="1104737at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013228">
        <property type="entry name" value="PE-PPE_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08237">
        <property type="entry name" value="PE-PPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049541" evidence="1">
        <location>
            <begin position="33"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="PE-PPE" evidence="2">
        <location>
            <begin position="72"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="251" mass="26126" checksum="9712B0B1AD28C5C4" modified="2010-04-20" version="1">MKLRAKKRTVVAVVSGVAAALAVVAGVQVAQADAPQHYYVEIGGTGSSLNAPDCTKTYGFANQNLGGAVAVPICYPASFGPLQGGDGTIPAPNAPRYDESVKQGVEETLKQIGDIHRNDPAATITVVGYSQGADVGDRVLEKIANGETEIPAEIMSGKLYADPRQPDTGIWAKVPAGTSIEGITSPGAGPVEFPGMTVERHCIAKDGVCDATSLDSFRGYFQDHPKYPAEGGIIPSTITAAPNNEVVWHQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4N5</accession>
    <name>D3Q4N5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2380"/>
    <dbReference type="EnsemblBacteria" id="ADD42065">
        <property type="protein sequence ID" value="ADD42065"/>
        <property type="gene ID" value="Snas_2380"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2380"/>
    <dbReference type="HOGENOM" id="CLU_936613_0_0_11"/>
    <dbReference type="OMA" id="MYISATD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="318" mass="32092" checksum="D11FD36E76F2DC85" modified="2010-04-20" version="1">MTYPPPPGVPGDPGQQPMPDPYAPGGGYAPPPSDPYGPPPQGDPYGAPQGDPYGAPPQDPYGTPPPDAYGSPPMSGVPMSPGAPGMAPDPYTQAPMPGMPGQQPSFLGGQPPKKSNLGWILGGVGGAAVLIILVVVGIVLVNSGGGGSDDTAGGGDKSNEQSGDPSESGDDGGSGEYAVSEGMCTKVDVSGVPSSIGLDKFDDISMDNEMYCSSMGSSSSLVSVKGKAYKDAKEAEAGYEEYKSTETVGGDGLQEFTGDWDKGEISQYANLEGTASVFILDGNMAITMYISATDKATNDEAKEAATVLAEGVFKAASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4X4</accession>
    <name>D3Q4X4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017725.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2471"/>
    <dbReference type="EnsemblBacteria" id="ADD42154">
        <property type="protein sequence ID" value="ADD42154"/>
        <property type="gene ID" value="Snas_2471"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2471"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_59_0_11"/>
    <dbReference type="OMA" id="CIVPPWR"/>
    <dbReference type="OrthoDB" id="1459004at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="220"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="35149" checksum="6F6AEC78522E2A89" modified="2010-04-20" version="1">MIERHKVAVLALDDVYPFDLGIPARVFRAMTPDDEPSPYEVVTCSVDGAPVRTNADYSLTVDHDASILAEADTVIVPPHGDPYPFGIDGTLPEPVAAALARIRPGTRIVSLCTAAYVLAAAGLLDHRPATTHWVAAEHFQGLYPDVDLDPGVLFVDDGDVLTSAGAGAAIDLCLHIVRRDHGSAAASNAARRCVVPPWRDGGQAQFIERPVPVATDSSTTATRAWALERLGQPLTLDDLAGHARMSRRTFTRRFRAEVGASPSQWLIQQRVDAARELLETSDLTTDRVARDCGFGTATSLRLHFHAELGVSPAAYRSTFRARSAAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4X5</accession>
    <name>D3Q4X5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017726.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2472"/>
    <dbReference type="EnsemblBacteria" id="ADD42155">
        <property type="protein sequence ID" value="ADD42155"/>
        <property type="gene ID" value="Snas_2472"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2472"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_11"/>
    <dbReference type="OMA" id="TSWQALK"/>
    <dbReference type="OrthoDB" id="1752728at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="14"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="314" mass="32927" checksum="BE5A6AB28AE2C90D" modified="2010-04-20" version="1">MNDTMRVVTQDALGDADVLRLDRAERPQPELTEILVRVKAAGLNPVDWKVRRTGTFLGEPPFRVGWDVSGVVEAVGAGVRTLAPGDEVLGMPRFPAPVGAYADYVTGPSRHFVRKPAALSHAEAAGLPLAGLTAWQALVDVADVQPGQRVLVHAAAGGVGHLAVQIAAAKGAHVIGTASAAKHPLLRELGAAEVIDYRTTDFTTVLSDVDVVLDAIGGDYGPRSLTVLRKGGILVSILSPEENALIEPAAEYGVNAGFVMVEPDQIGLLGLVDLIEAGKLRIHVDRAFDLDDVVAAHELLESGHVTGKVVLTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q560</accession>
    <name>D3Q560_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_4464</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019680.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4464"/>
    <dbReference type="EnsemblBacteria" id="ADD44109">
        <property type="protein sequence ID" value="ADD44109"/>
        <property type="gene ID" value="Snas_4464"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4464"/>
    <dbReference type="eggNOG" id="COG1087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_10_11"/>
    <dbReference type="OMA" id="QMVESAW"/>
    <dbReference type="OrthoDB" id="1597849at2"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="8">
        <location>
            <begin position="3"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="324" mass="34610" checksum="897FCE9344B817AD" modified="2010-04-20" version="1">MSWLVTGGAGYIGGHVVRRMRAQGYQVVVYDDLSTGVADRVPEGVPLCVGNLLDRDALTDVMRIHNVTGVVNLAARKSVPESTSDPMLYHRDNVSGFIAVLDAMKDAGVRHIVQSSSAAIYGGAPGPVHAEITPADPLSPYATTKLMAELILKDAAAAGHLSYLALRYFNPVGALAPELAEVGGANVFTILFNAIDSGEVFGVTGDDFDTRDGSGLRDYIHIEDLADAHVAAVEYISGHEAGDVVNIGTGRGYTVFEMLEAVRQVTGQPVPHKVVDRRPGDAAGAVAAVERAERLLGWRARYDLMDMVDSAWTMWRAQRDGVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q595</accession>
    <name>D3Q595_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 20">Methionine synthase</fullName>
            <ecNumber evidence="6 20">2.1.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19 20">5-methyltetrahydrofolate--homocysteine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="31" type="ordered locus">Snas_4499</name>
    </gene>
    <organism evidence="31 32">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="31 32" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="32">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18 20">Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:11172"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="2.1.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 20 23">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 20 22">
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 20">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetH route): step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="20">Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the vitamin-B12 dependent methionine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.13" evidence="6 20"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019715.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4499"/>
    <dbReference type="EnsemblBacteria" id="ADD44144">
        <property type="protein sequence ID" value="ADD44144"/>
        <property type="gene ID" value="Snas_4499"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4499"/>
    <dbReference type="eggNOG" id="COG0646">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1410">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004914_4_0_11"/>
    <dbReference type="OMA" id="ADCIAMS"/>
    <dbReference type="OrthoDB" id="118138at2"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008705">
        <property type="term" value="F:methionine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042558">
        <property type="term" value="P:pteridine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02069">
        <property type="entry name" value="methionine_synthase_B12_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="3.10.196.10">
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
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    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003726">
        <property type="entry name" value="HCY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036589">
        <property type="entry name" value="HCY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033706">
        <property type="entry name" value="Met_synthase_B12-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011822">
        <property type="entry name" value="MetH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004223">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037010">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02965">
        <property type="entry name" value="Met_synt_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000381">
        <property type="entry name" value="MetH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01018">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47644">
        <property type="entry name" value="SSF47644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56507">
        <property type="entry name" value="SSF56507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82282">
        <property type="entry name" value="SSF82282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02082">
        <property type="entry name" value="metH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50974">
        <property type="entry name" value="ADOMET_ACTIVATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51337">
        <property type="entry name" value="B12_BINDING_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50970">
        <property type="entry name" value="HCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 20" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 20 22" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="17 20 21" id="KW-0170">Cobalt</keyword>
    <keyword evidence="13 20 21" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16 20" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8 20 24" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="32" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0677">Repeat</keyword>
    <keyword evidence="12 20 22" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11 20 24" id="KW-0808">Transferase</keyword>
    <keyword evidence="15 20 21" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Hcy-binding" evidence="26">
        <location>
            <begin position="3"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Pterin-binding" evidence="27">
        <location>
            <begin position="336"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding N-terminal" evidence="30">
        <location>
            <begin position="628"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="29">
        <location>
            <begin position="721"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="domain" description="AdoMet activation" evidence="28">
        <location>
            <begin position="880"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Methylcob(III)alamin binding" evidence="22">
        <location>
            <begin position="731"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="870"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="22">
        <location>
            <begin position="1169"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="25">
        <location>
            <begin position="870"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="21">
        <location>
            <position position="734"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
        <ligandPart>
            <name>Co</name>
            <dbReference type="ChEBI" id="CHEBI:27638"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="779"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="838"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="927"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="1115"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00025552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00031040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRNR" id="PIRNR000381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS50974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="PROSITE" id="PS51337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="EMBL" id="ADD44144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1173" mass="128296" checksum="FCEDD5CECEE74B2A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5B9</accession>
    <name>D3Q5B9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">1-deoxy-D-xylulose-5-phosphate synthase</fullName>
            <ecNumber evidence="10">2.2.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">1-deoxyxylulose-5-phosphate synthase</fullName>
            <shortName evidence="10">DXP synthase</shortName>
            <shortName evidence="10">DXPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dxs</name>
        <name evidence="13" type="ordered locus">Snas_4523</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:12605"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="10">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the transketolase family. DXPS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.7" evidence="10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019739.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4523"/>
    <dbReference type="EnsemblBacteria" id="ADD44168">
        <property type="protein sequence ID" value="ADD44168"/>
        <property type="gene ID" value="Snas_4523"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4523"/>
    <dbReference type="eggNOG" id="COG1154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009227_1_4_11"/>
    <dbReference type="OMA" id="FAPQGMF"/>
    <dbReference type="OrthoDB" id="566385at2"/>
    <dbReference type="UniPathway" id="UPA00064">
        <property type="reaction ID" value="UER00091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008661">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052865">
        <property type="term" value="P:1-deoxy-D-xylulose 5-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="TPP_DXS"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DXP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Dxylulose-5-P_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322">
        <property type="entry name" value="PTHR43322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13292">
        <property type="entry name" value="DXP_synthase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00204">
        <property type="entry name" value="dxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="12">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="155"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD44168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="644" mass="68510" checksum="5653267CE08DCA68" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5J6</accession>
    <name>D3Q5J6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="Snas_6440"/>
    </dbReference>
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    <dbReference type="OMA" id="WPRWLPV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD46056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="311" mass="32609" checksum="3A747F12DA1B26EE" modified="2010-04-20" version="1">MSSLVSKVVAELGIALEWLTAPHPATIHLHAGSHVGDELSKQISGRVQRLREADDTVPGRILYPHVIAERDQVATLLDNANANTRTRTVLLTALAELEQLAGWIAADGNASAQAQTHYLAGIRAANEAGDPVTAAQLWSCLAYMFTGNGDAVDGLFVAEAARRRGELSSPLVACLLAERHAYAAAVASDSYACHMALADADALLAAASPDIPEPAWVYWLDAAEVAVMAGRCMLLLGKPDRAVPLLRDAIASYPADHAREVALYRGWLAAAYAAAGDREAAQAEADAAAIIAGGAGVDSERVADRLDSVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5K6</accession>
    <name>D3Q5K6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6451"/>
    <dbReference type="EnsemblBacteria" id="ADD46066">
        <property type="protein sequence ID" value="ADD46066"/>
        <property type="gene ID" value="Snas_6451"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6451"/>
    <dbReference type="eggNOG" id="COG4758">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075817_4_1_11"/>
    <dbReference type="OMA" id="GRWVVPR"/>
    <dbReference type="OrthoDB" id="1687355at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012551">
        <property type="entry name" value="DUF1707"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08044">
        <property type="entry name" value="DUF1707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD46066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="192" mass="21485" checksum="9B69D9F96F80A501" modified="2010-04-20" version="1">MSGDLERAELRISNADRERTIEHLQNCTSEGRLTLDEFTERVDAVYEAKTYGELKPLLSDLPVAGDVTTPVGASDLDDISPTGSALRRTGRWLVPRRITLRPKGSSVLLNFAHAALGHREVEIVLAAKASSIVLVLPRNAWADGRVDTKYSSFANRAQNPGDEAAVRFHVHGELHSSSLRIRRVRRFLWWEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6L2</accession>
    <name>D3Q6L2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019826.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4612"/>
    <dbReference type="EnsemblBacteria" id="ADD44255">
        <property type="protein sequence ID" value="ADD44255"/>
        <property type="gene ID" value="Snas_4612"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4612"/>
    <dbReference type="eggNOG" id="COG3568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060500_4_2_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048277" evidence="1">
        <location>
            <begin position="32"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="40"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="268" mass="28342" checksum="D506DA03A90DAF8B" modified="2010-04-20" version="1">MRIRYLVATPILSLAAIVALTGPVVATPQEAKSVVRVLNYNIQAGRGAGEDPNVDPPNIPRTAAAIREHDPDIVTLQEVHQPDTSGADQVAQLAAELDMNAYFGPADGNGSGGQAGNAILTKLPIVERVNRRLPDDPDTNNVKRALAGAKLDLGGGAFIRVFTTHLSPGLSDAVVAEREAQGRWALDYLSHSGPLLFTGDFNERPENRIHAWALADGFADTGGEVAPDPTHGDARIDFVYARGVTATAGLVPDTDASDHRPVVIDLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Q0</accession>
    <name>D3Q6Q0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4650</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019864.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4650"/>
    <dbReference type="EnsemblBacteria" id="ADD44293">
        <property type="protein sequence ID" value="ADD44293"/>
        <property type="gene ID" value="Snas_4650"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4650"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_11"/>
    <dbReference type="OMA" id="WTIPTFG"/>
    <dbReference type="OrthoDB" id="1510342at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="96"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="314" mass="34113" checksum="6028142E64F731F0" modified="2010-04-20" version="1">MSTNAKKAPDVEPVELAKRARSRFSRPWASITAIVIALLWTTPTAGLLISSFRPENEIKTTGWWTMFTGGNAQLTIANYNEVLYGASSSGQLAESFINSLIITVPSVLFPLALAALAAYALSWVQFKGRDWVFIAIFALQVVPLQMALIPLLSFFSEGASVSGTQLLPAWGLEGEWEFVQVWFAHTAFGLPLGIFLLHNFMSELPGSVIESARVDGASHGAIFRRIVLPLITPALASLAIFQFLWVWNDLLVALVFASDTPPLTAKLADMAGSRGNEWQRLTAGAFISIVIPIGVFLGLQRYFVRGLLAGSVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q791</accession>
    <name>D3Q791_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2685"/>
    <dbReference type="EnsemblBacteria" id="ADD42362">
        <property type="protein sequence ID" value="ADD42362"/>
        <property type="gene ID" value="Snas_2685"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2685"/>
    <dbReference type="HOGENOM" id="CLU_2048304_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048291" evidence="1">
        <location>
            <begin position="34"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="120" mass="12857" checksum="9DD33DA3D17D05EA" modified="2010-04-20" version="1">MKRMKLVFVAAATVALVGGATAYATADDLGAKAAPIAKNAYGYITFIDNGDKFKVCDTKKDGRGVVGSVHDTREMLDYDTDGGDSGCDYFTYDVVEGPEYHLEIERIGGGSRAHSVGFYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7B5</accession>
    <name>D3Q7B5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017957.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2710"/>
    <dbReference type="EnsemblBacteria" id="ADD42386">
        <property type="protein sequence ID" value="ADD42386"/>
        <property type="gene ID" value="Snas_2710"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2710"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_6_1_11"/>
    <dbReference type="OrthoDB" id="1893149at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="20"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="156" mass="16747" checksum="0F5328A689EE3628" modified="2010-04-20" version="1">MTATSRFSNPVALIPALADITAAVNKVNADGTLPQTTVDLLQLRVGQILGSAYFTVRVLRQSEDTAERLGAVATWREAPCFTEAERAALALAEAVHTPNPSGDRVSDEVYAEAAKHYDERELVTLTSVLGQMGFYIPLALIGQPIPGVAPAEQWQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7D3</accession>
    <name>D3Q7D3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2728</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017975.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2728"/>
    <dbReference type="EnsemblBacteria" id="ADD42404">
        <property type="protein sequence ID" value="ADD42404"/>
        <property type="gene ID" value="Snas_2728"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2728"/>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_1_11"/>
    <dbReference type="OMA" id="ATAYHTD"/>
    <dbReference type="OrthoDB" id="1911275at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="24263" checksum="E3E3F62ABE27E99E" modified="2010-04-20" version="1">MVIERRPLRDEIKREVLERFRRGDYPAGHNIRESQLAADLGVSRTPLREALIALEIEGLIKSQPGKGFRFAPVSPKEYKELGPVVAALEALALETSDRDYIDTTAPRLLALATEFDASVATQAEIDERDDEWHDLLLGGCDNERLMDLLTTLKASLRRYVHLLVDDETQLSRSAGEHQLIAERLIAGDLPGAVEALKANWSSGSARILEKLAELDGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7E8</accession>
    <name>D3Q7E8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GreA/GreB family elongation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017990.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2743"/>
    <dbReference type="EnsemblBacteria" id="ADD42419">
        <property type="protein sequence ID" value="ADD42419"/>
        <property type="gene ID" value="Snas_2743"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2743"/>
    <dbReference type="eggNOG" id="COG0782">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101379_2_1_11"/>
    <dbReference type="OMA" id="GMVGDHG"/>
    <dbReference type="OrthoDB" id="1536415at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GreA_GreB" evidence="1">
        <location>
            <begin position="82"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="152" mass="15937" checksum="A0F9E9004FC5E012" modified="2010-04-20" version="1">MAGKSAPIGANARHTLEQDLAEVRAERDRVAATLTDTDTTGDSADQAQELQRVTDLQLLDARVEKLTARLDASATATQGRTDLVDVGSTVTIRFSDDTTETLHIGEIADVDDQLLVTAGSPLGRALLGHRAGDTVSYNTPSGHATAVVESLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7F0</accession>
    <name>D3Q7F0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pirin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2745</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017992.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2745"/>
    <dbReference type="EnsemblBacteria" id="ADD42421">
        <property type="protein sequence ID" value="ADD42421"/>
        <property type="gene ID" value="Snas_2745"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2745"/>
    <dbReference type="eggNOG" id="COG1741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045717_1_0_11"/>
    <dbReference type="OMA" id="RPHPHIN"/>
    <dbReference type="OrthoDB" id="833478at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PTHR13903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin" evidence="4">
        <location>
            <begin position="37"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin_C" evidence="5">
        <location>
            <begin position="189"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="319" mass="34733" checksum="FFA1B2272455DB24" modified="2010-04-20" version="1">MSNPETAPREVRCENTDGGAEILEPREVPLGGPRAMTVRRTLPQRSRSLIGAWCFVDHYEPDDVADSGGMRVDGHPHTGLQTVSWLFEGEIEHRDTAGHHAMVRPGELNLMTAGSGIAHSEYSMPGTRRLHGAQLWVALPESDRFTAPGFTHYAPQPFERDGATVLVFLGSLLGETSPVSTFTPLLGAELTLPPGRLDLHVEPGHEHGVLVDSGDVTLAGLTAGPGQLVYRPPGHSRLELSTERGCRILLLGGTPLGERITMWWNFIGRGHDEIAAFREEWQAAREPGAAVGRFGPFPEQWEETLPAPGLPNVRLKPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7K5</accession>
    <name>D3Q7K5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gas vesicle G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4704</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019918.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4704"/>
    <dbReference type="EnsemblBacteria" id="ADD44347">
        <property type="protein sequence ID" value="ADD44347"/>
        <property type="gene ID" value="Snas_4704"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4704"/>
    <dbReference type="eggNOG" id="ENOG50331Q2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162460_1_0_11"/>
    <dbReference type="OMA" id="VIWVAEK"/>
    <dbReference type="OrthoDB" id="2088186at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007804">
        <property type="entry name" value="Gas-vesicle_GvpG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05120">
        <property type="entry name" value="GvpG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="81" mass="8942" checksum="6E591ECAF2D8E402" modified="2010-04-20" version="1">MFGLLLAPVLGVVRLAELIHREAERQYRDPAAVMGALEAVDAARRNGELSETEAEQAERELLARLYPPRPAGSLLPPSHER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7X9</accession>
    <name>D3Q7X9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0772"/>
    <dbReference type="EnsemblBacteria" id="ADD40484">
        <property type="protein sequence ID" value="ADD40484"/>
        <property type="gene ID" value="Snas_0772"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0772"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_4_11"/>
    <dbReference type="OMA" id="EVSGIEC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="15"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="34824" checksum="71090284ADB63F43" modified="2010-04-20" version="1">MTTPTMRAARLREPGPVTNLELVDLPVPEPRPGWVRVKVEAFGLNRSELHTRLGLAEGVTFPRVLGIECVGVVDADPDGDLEGRQVAAMMGDMGRRYDGGYAEYTVVPRSNVVPFRSALPWEVIGAVPETLQTAYGSLTTGLDLHAGQTLLIRGGTSALGLVAATLAKDIGATVLSTTRNPDRAEALLRQGVDQAVVDDGHIADTVRGLCPGGVDAALELVGTPTLPDTLAATRVHGTVCFTGMLSNEWIVPNFYPIGYIPKGVRLTGYGGESEDLPSEVLQDHLDKLASGAVNPGPTHVYTLDDIRRAHDDLEHNRVFGKLVVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Y2</accession>
    <name>D3Q7Y2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylmalonyl-CoA mutase, large subunit</fullName>
            <ecNumber evidence="4">5.4.99.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0775</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.2" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016058.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0775"/>
    <dbReference type="EnsemblBacteria" id="ADD40487">
        <property type="protein sequence ID" value="ADD40487"/>
        <property type="gene ID" value="Snas_0775"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0775"/>
    <dbReference type="eggNOG" id="COG1884">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009523_5_1_11"/>
    <dbReference type="OMA" id="LPRWNTI"/>
    <dbReference type="OrthoDB" id="154460at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004494">
        <property type="term" value="F:methylmalonyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006098">
        <property type="entry name" value="MMCoA_mutase_a_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00641">
        <property type="entry name" value="acid_CoA_mut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="METMALONYL_COA_MUTASE" evidence="3">
        <location>
            <begin position="7"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="526" mass="57496" checksum="F15260852C9C06C2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q814</accession>
    <name>D3Q814_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016090.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0807"/>
    <dbReference type="EnsemblBacteria" id="ADD40519">
        <property type="protein sequence ID" value="ADD40519"/>
        <property type="gene ID" value="Snas_0807"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0807"/>
    <dbReference type="eggNOG" id="COG1359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131496_13_2_11"/>
    <dbReference type="OMA" id="NVYERWE"/>
    <dbReference type="OrthoDB" id="1909149at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="2"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="95" mass="10073" checksum="A42DD70702414956" modified="2010-04-20" version="1">MVIVAGQLTVAPSQLESYLASCVSVVEQARRAPGCLDFTIAADPLDPGRVNVYERWESREAVEAFRGSGPSDEQAATILGASVAEYDIAATRSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q865</accession>
    <name>D3Q865_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018010.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2763"/>
    <dbReference type="EnsemblBacteria" id="ADD42439">
        <property type="protein sequence ID" value="ADD42439"/>
        <property type="gene ID" value="Snas_2763"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2763"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_6_11"/>
    <dbReference type="OMA" id="DHWIAER"/>
    <dbReference type="OrthoDB" id="1616572at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="9"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="291" mass="31410" checksum="17272B09B29A7B52" modified="2010-04-20" version="1">MSRTILVTGATGTVSTALISELAEADVNLRALAQEASDMDGLRERGIEVVVGDLDDPDTLPPAFAGVHDLWLLNPNGPRAPENNMNAVWAARQSGVERVVRLSAIGAAFDAPNRSGRLHALSDREVEASGMRWTILRPFWFMQNLLNEAADIAATGTFSLNMASARLGMIDARDIAACAARILLDEPDRHHGTAYTLSGPRSLTFDEVADELGDALGGLVKYSPVSDAAKRETLLGFGVPKWIVDMLEEYARAYVSGWGDYTTDSVSELLGRPPRDIAEFARDHASAFRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8B5</accession>
    <name>D3Q8B5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Non-homologous end joining protein Ku</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ku</name>
        <name evidence="5" type="ordered locus">Snas_2813</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer. Interacts with LigD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic Ku family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018060.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2813"/>
    <dbReference type="EnsemblBacteria" id="ADD42489">
        <property type="protein sequence ID" value="ADD42489"/>
        <property type="gene ID" value="Snas_2813"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2813"/>
    <dbReference type="eggNOG" id="COG1273">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048975_1_1_11"/>
    <dbReference type="OMA" id="HAMRWPD"/>
    <dbReference type="OrthoDB" id="1724780at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00789">
        <property type="entry name" value="KU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01875">
        <property type="entry name" value="Prokaryotic_Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006164">
        <property type="entry name" value="Ku70/Ku80_beta-barrel_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009187">
        <property type="entry name" value="Prok_Ku"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41251">
        <property type="entry name" value="PTHR41251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006493">
        <property type="entry name" value="Prok_Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00559">
        <property type="entry name" value="Ku78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SSF100939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02772">
        <property type="entry name" value="Ku_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ku" evidence="4">
        <location>
            <begin position="52"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="251"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="256"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="284" mass="31854" checksum="FDDE7C33B8E1D119" modified="2010-04-20" version="1">MRASWKGSIVWSLVSMPVKLVPATEDKDVRFHQVHRTDGGRIRQRRFCEIEDVEVPYSEIAKGYELQSGEVVILEKSDFDALPLPSKKTIDVAEFVDAGDIDPVYFSRSYYVEPDRPVKPYVLMRDSLAAAGRVAIAKIALTNREHLAVLRPRDDFLMLHIVYWPDEVRKPEFESLGDTVTVSRQEISMAKKLIESMTVDALDMNEFHDDYRAALLKTIDAKVAGNATVQPEDAEEGGKVIDLMEALEKSLSKTRSKKAPAKKAAKKTTAKKTAKKSSKSRKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8W3</accession>
    <name>D3Q8W3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Extracellular solute-binding protein family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0861</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial solute-binding protein 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0861"/>
    <dbReference type="EnsemblBacteria" id="ADD40572">
        <property type="protein sequence ID" value="ADD40572"/>
        <property type="gene ID" value="Snas_0861"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0861"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_18_2_11"/>
    <dbReference type="OMA" id="DTPFENF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018313">
        <property type="entry name" value="SBP_3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01039">
        <property type="entry name" value="SBP_BACTERIAL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048955" evidence="4">
        <location>
            <begin position="26"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="5">
        <location>
            <begin position="32"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="PBPe" evidence="6">
        <location>
            <begin position="32"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="257" mass="28607" checksum="32065DAD2EE9BBFE" modified="2010-04-20" version="1">MTRSSTPVRSLTAIGTALTLTLGLAACSSQDTLTVCTSIPYEPFQFKDSWQDNKVVGFDVDIMDLVAKELDLKQEIVDIGFEQIDSGQALEEGTCDVAAAALTITPPREEVMSFSDPYYDAKQALGAKPGSKIKTLKDMKGKVLGVQRDSTGFAYADENQDKYEYDLKTYNDLGKLREAVLYDQVDAAINDVPLWTSKVTDDQRKLEIIEKYDTGEEYGYAVAKDNDELLSTINEVLAKSRKNGDFEEIYQKWIGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q918</accession>
    <name>D3Q918_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphomethylpyrimidine synthase</fullName>
            <ecNumber evidence="10">4.1.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Hydroxymethylpyrimidine phosphate synthase</fullName>
            <shortName evidence="10">HMP-P synthase</shortName>
            <shortName evidence="10">HMP-phosphate synthase</shortName>
            <shortName evidence="10">HMPP synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thiamine biosynthesis protein ThiC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">thiC</name>
        <name evidence="12" type="ordered locus">Snas_0916</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + S-adenosyl-L-methionine = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-deoxyadenosine + CO + formate + 3 H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:24840"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="EC" id="4.1.99.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ThiC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.17" evidence="10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016198.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0916"/>
    <dbReference type="EnsemblBacteria" id="ADD40627">
        <property type="protein sequence ID" value="ADD40627"/>
        <property type="gene ID" value="Snas_0916"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0916"/>
    <dbReference type="eggNOG" id="COG0422">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013181_2_1_11"/>
    <dbReference type="OMA" id="TWELFRD"/>
    <dbReference type="OrthoDB" id="505395at2"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00089">
        <property type="entry name" value="ThiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037509">
        <property type="entry name" value="ThiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025747">
        <property type="entry name" value="ThiC-associated_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038521">
        <property type="entry name" value="ThiC/Bza_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002817">
        <property type="entry name" value="ThiC/BzaA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30557">
        <property type="entry name" value="PTHR30557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13667">
        <property type="entry name" value="ThiC-associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01964">
        <property type="entry name" value="ThiC_Rad_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00407">
        <property type="entry name" value="phosphomethylpyrimidine_syntha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00190">
        <property type="entry name" value="thiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ThiC-associated" evidence="11">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="244"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="285"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="472"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD40627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="516" mass="56823" checksum="5F71B694BA44CF9B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q925</accession>
    <name>D3Q925_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsI</name>
        <name evidence="9" type="ordered locus">Snas_0923</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016205.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0923"/>
    <dbReference type="EnsemblBacteria" id="ADD40634">
        <property type="protein sequence ID" value="ADD40634"/>
        <property type="gene ID" value="Snas_0923"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0923"/>
    <dbReference type="eggNOG" id="COG0103">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046483_2_0_11"/>
    <dbReference type="OMA" id="QWKINGR"/>
    <dbReference type="OrthoDB" id="1766414at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_S9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_S9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_S9_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="122"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="154" mass="16692" checksum="3814865575C94CD2" modified="2010-04-20" version="1">MSEMTPAVPAPTSVPAAPPVAPAIPVDRPVQTVGRRKRAIVRTRLVPGTGKFILNGKTLEGYFPSKVHQQIVAEPLVTTERSETYDVIANLKGGGVTGQAGALRLGIARALIELEPESRGPLKRAGYLTRDPREKESKKYGLKKARKAPQYSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9G1</accession>
    <name>D3Q9G1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018214.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2968"/>
    <dbReference type="EnsemblBacteria" id="ADD42643">
        <property type="protein sequence ID" value="ADD42643"/>
        <property type="gene ID" value="Snas_2968"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2968"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061176_2_0_11"/>
    <dbReference type="OMA" id="DRFGYWP"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="333" mass="36056" checksum="8E60A840965EDBD7" modified="2010-04-20" version="1">MRILVLGGTVFLSKAVAVQAMERGHDVTVAARGESGQPPQGARFVKLDRDNPGEGLAALSRETFDAVVDVARIPAQVKAVLAALADRVGHWSFVSTVNVYADNSIPGQHPGNGKLNDPIDEDSTDPDIEVYGASKVACENLVRSAVGDKAFIARPGLIIGPGDPGYRFGYWPDRLAEAGEVLAPGDPQRLVQWIDVRDHAEWIIDAAENQVVGTFDAVCPPVPFQRFLDGVAEGMGTTPEFTWVDQDFVQAHEINPWSGEQSLPMWLPLPEYAGMLTHDVTASVAAGMRNRPVAESAADWYASMKDKPRDPQKGLTRAREAEVLAAWHGRDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9R7</accession>
    <name>D3Q9R7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Small multidrug resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4975</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020184.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4975"/>
    <dbReference type="EnsemblBacteria" id="ADD44613">
        <property type="protein sequence ID" value="ADD44613"/>
        <property type="gene ID" value="Snas_4975"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4975"/>
    <dbReference type="eggNOG" id="COG2076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133067_0_3_11"/>
    <dbReference type="OMA" id="SMNIGIA"/>
    <dbReference type="OrthoDB" id="1921902at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="122" mass="12648" checksum="68518CE03266E19C" modified="2010-04-20" version="1">MNKWLMLGIAIALEVGATLSLRAMSGLEHPWFLAAVVAGYVGAFYFVAKLLETGMQVGVAYGVWAASGVALTAILGSLLFGDPLTWQVGAGIGLIIGGVLLVEIGSQRAEETREVLTPTGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9T6</accession>
    <name>D3Q9T6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative phosphohistidine phosphatase, SixA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4995</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4995"/>
    <dbReference type="EnsemblBacteria" id="ADD44632">
        <property type="protein sequence ID" value="ADD44632"/>
        <property type="gene ID" value="Snas_4995"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4995"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2062">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048989_0_0_11"/>
    <dbReference type="OMA" id="RYDDWSW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="3"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="301" mass="32171" checksum="2A0CB62C60EFD0A8" modified="2010-04-20" version="1">MNDRVLAAGGVLWRPAAPDNASTDTVEVAGVYRPETRNWSLPKGKLDDGEHPLSAACREVAEETGLTPIPQAFLVTARYTLPREGGEIEKIVDYWSMRALDERATFTPTAEVTEQRWFGLAEAEKVLTRPRDQVALGAFRDLPRVTATVLLLRHAQAEPETAYPGADVARPLNATGRGDSARLVPLLALYNPHRIVAATPLRCVKTVTPLSAALGLEIQGEEVFDATGHPGNPERAAARLRELATGGGGVVCSQLPVIADSLAILADTDGVAMPSVHTPPGGVWVLSFSHKTLVAAERLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9X6</accession>
    <name>D3Q9X6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5035</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020243.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5035"/>
    <dbReference type="EnsemblBacteria" id="ADD44672">
        <property type="protein sequence ID" value="ADD44672"/>
        <property type="gene ID" value="Snas_5035"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5035"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064468_0_0_11"/>
    <dbReference type="OMA" id="SFVGAEW"/>
    <dbReference type="OrthoDB" id="2025372at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="44"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="341" mass="37093" checksum="93F77565B94887CB" modified="2010-04-20" version="1">MRLLSVELRRFASRRANILFAVIGLLFLAGSLTVLGLSTHKPTEAEISRAESQAEEEREVTERELKECEDYWAENPDADPENPDPDDFESGKVEDYGYTPDCEYLQQPSDVQASDYLGQVISFADEAEGQIIFLGVVFVVCALLMSGSFVGAEWTSGGMTNLLLWRPRRTAVYASKLTAALLAVLTLTIVASVLHIGGLYLLAVTNGDVGTLTPSWWQDNGNLALRFLALVAMATVIGVSLSMIGRRTVVAIGSVVAYLVVVEYGIRGLLSTVNTHFVDYWMLSTYVGAWLVGKQQVYSSYLDGTAQVETIYMWHGGGVLAAVTAILLAGSAVLFARRDTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA17</accession>
    <name>D3QA17_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aldose 1-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016300.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1019"/>
    <dbReference type="EnsemblBacteria" id="ADD40729">
        <property type="protein sequence ID" value="ADD40729"/>
        <property type="gene ID" value="Snas_1019"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1019"/>
    <dbReference type="eggNOG" id="COG2017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052486_1_1_11"/>
    <dbReference type="OMA" id="WAVAVEP"/>
    <dbReference type="OrthoDB" id="710313at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09022">
        <property type="entry name" value="Aldose_epim_Ec_YihR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037480">
        <property type="entry name" value="YihR-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="299" mass="32833" checksum="F1A973CD3F93B951" modified="2010-04-20" version="1">MALSGEQWTIGYSGREAVIASVGGGLRSFSVDGRSYVDAYEDDELAPGWAGHVLAPWPGRLADGEYSFDDERHKLPWNEPANRVALHGLVGWLRWRAVDVSDSSVTVECDLSPQPGYPFQLVLRTRWSVGPYGLRAVHTASNVGTRSCPLGLGVHPYLMLPNSPLDKWRLRVPAKKQLLTDERKLPSGETQAAFTEATAIGDTVLDTTFGDLERDSDGIARLELSNEDDSESVVVWVDDSFGWLHLYTGDQLDGERRRRSLAVEPMSCPPDALRSGTGLVTLSPFDAWSGTWGITPRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA31</accession>
    <name>D3QA31_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1033</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016314.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1033"/>
    <dbReference type="EnsemblBacteria" id="ADD40743">
        <property type="protein sequence ID" value="ADD40743"/>
        <property type="gene ID" value="Snas_1033"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1033"/>
    <dbReference type="eggNOG" id="COG1125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_5_11"/>
    <dbReference type="OMA" id="QHDAGWV"/>
    <dbReference type="OrthoDB" id="1220708at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="322" mass="34359" checksum="A064F00FC8381B5A" modified="2010-04-20" version="1">MSSATAAPIRLDGVEKIYDGGGTAVADLSLDIAAGELVALVGPSGCGKSTVLRMINRLIEPTSGSIYVDGEDVTSSDPVELRRRIGYCIQHIGLFPHQTVAANVATVPRLLGWDRDKATERVEELLDLVGLDVGIHGKRYPHQLSGGQRQRVGVARALAADPVVLLMDEPFSAVDPIARGRLQEEFLRLQADVGKTIVFVTHDVDEAIRLGDKIAVLSNEAKLEQYGTPAEILRRPKTSFVSEFVGADRGVKSLSVTGLAQAQLRELPPGEHPTVTSAANLREALSRLLDGETGFVSVTESGHSLGGLSADDIYRALHSDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA45</accession>
    <name>D3QA45_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1047"/>
    <dbReference type="EnsemblBacteria" id="ADD40757">
        <property type="protein sequence ID" value="ADD40757"/>
        <property type="gene ID" value="Snas_1047"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1047"/>
    <dbReference type="eggNOG" id="COG2223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035309_1_1_11"/>
    <dbReference type="OMA" id="QFHAGFS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="387" mass="38611" checksum="6B26E31DC5359E00" modified="2010-04-20" version="1">MAVTAAFIVHGLVFSSWLPHIPAIKDDLRLSEGTLGLVLLAPPLGAIVAMSLTGAACARWGSAAVTRVTLVVYALGITAIGVGAGTTWGLSLALLWAGALVGSFDVAMNAQGATVEKAMGKSIMGSFHAAWSLAAAAGAGIGGWVAAVDEDLFTTQLFAVGMIALLAALPFFTSFIPDAPPEAHAKGRKWRFERGLVLLSMVAFAGLLAEGAVADWSAVFLSQERGASPMVAGWAYAVFSVAMLIGRLAGDRLVGRFGRSRSVAVAALTGGGGMAVGLVVSQLAGDSGLGQASFIAGLFILGLGIAVIVPVAFSSAGDGPGIATVSTGGYTGWLLGPAVIGGLGELMGLSAAIWVVAVLAVFAGLVAPLGIGALRGASDKEKAAAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAA1</accession>
    <name>D3QAA1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1103</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016384.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1103"/>
    <dbReference type="EnsemblBacteria" id="ADD40813">
        <property type="protein sequence ID" value="ADD40813"/>
        <property type="gene ID" value="Snas_1103"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1103"/>
    <dbReference type="HOGENOM" id="CLU_1776310_0_0_11"/>
    <dbReference type="OrthoDB" id="2195437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="146" mass="15708" checksum="C6DE370BE530DA60" modified="2010-04-20" version="1">MESNPSRWFSYGAMVIAVLSLAACGGEPDVSKKPADESPEAVVCEVGGDFSGSVTAEATSGAAEEDWEGEDFGPMNLVVVYLESPTESDAVTVVVRDGDGEELTRNLYQIDTPLDEIEFEGGHGFTGLHYVNHDDAQLQYWCAPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAG1</accession>
    <name>D3QAG1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3073</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018315.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3073"/>
    <dbReference type="CAZy" id="GH20">
        <property type="family name" value="Glycoside Hydrolase Family 20"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42744">
        <property type="protein sequence ID" value="ADD42744"/>
        <property type="gene ID" value="Snas_3073"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3073"/>
    <dbReference type="eggNOG" id="COG3525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020160_1_0_11"/>
    <dbReference type="OMA" id="DKYCKER"/>
    <dbReference type="OrthoDB" id="727559at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102148">
        <property type="term" value="F:N-acetyl-beta-D-galactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="PTHR22600"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="SSF55545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_20b" evidence="6">
        <location>
            <begin position="27"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_20" evidence="5">
        <location>
            <begin position="90"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="591" mass="65002" checksum="2EE7C064BA6338A5" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAI3</accession>
    <name>D3QAI3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018337.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3095"/>
    <dbReference type="EnsemblBacteria" id="ADD42766">
        <property type="protein sequence ID" value="ADD42766"/>
        <property type="gene ID" value="Snas_3095"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3095"/>
    <dbReference type="eggNOG" id="COG3467">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127487_1_1_11"/>
    <dbReference type="OMA" id="RWWPPLD"/>
    <dbReference type="OrthoDB" id="1804797at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024747">
        <property type="entry name" value="Pyridox_Oxase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12900">
        <property type="entry name" value="Pyridox_ox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="164" mass="17611" checksum="90532C12E8AC22C7" modified="2010-04-20" version="1">MEGHGDTENNNAHASEAVSRGNGVVTLDTITTRECVDLLRESTVGRLGVTDRAMPMILPVNFQVYNDWVVVRTVPGSTMAEAARNSVVAFEVDQADFSKRTGWSVVVVGHASLISGGPVFETLCGLDLLAWAPHEEDGFLVIKMERVSGRRLAIAAESGTGIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB56</accession>
    <name>D3QB56_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CbiA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016444.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1163"/>
    <dbReference type="EnsemblBacteria" id="ADD40873">
        <property type="protein sequence ID" value="ADD40873"/>
        <property type="gene ID" value="Snas_1163"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1163"/>
    <dbReference type="eggNOG" id="COG0455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_914287_0_0_11"/>
    <dbReference type="OMA" id="FHRWTRQ"/>
    <dbReference type="OrthoDB" id="1203604at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="305" mass="33463" checksum="6DE41CBA5A904293" modified="2010-04-20" version="1">MLVFATSDKGGTGRSVTSCNLAYRSALRGKNVCYVDYDFGSPTAGAVFGIEVVARGTDAGGLHEYLLGHTPDPHRVNVWDKSERNSIRRRPDTSGDLVLMPGDRGGGEFASSPEIVERCTDLFLRLEEQFDISIVDLSAGRSYAAEIVLGALAAPDMEGVVARWLIHHRWTRQHILAAAGLLDGERGILDIGVQLGHDKRRLRESVRYVRTAVVDPDADDLAGLRAPQVAWLHDCNDSLNKLASREAIGRANTLGDVPLDPVLQWREQILTESDTHTREIANVATVRAFEDLADRLTDDVAWEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB58</accession>
    <name>D3QB58_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PfkB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1165</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016446.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1165"/>
    <dbReference type="EnsemblBacteria" id="ADD40875">
        <property type="protein sequence ID" value="ADD40875"/>
        <property type="gene ID" value="Snas_1165"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1165"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_6_2_11"/>
    <dbReference type="OMA" id="NWRPTFW"/>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="5">
        <location>
            <begin position="3"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="312" mass="32776" checksum="CC6BC8E5C212B494" modified="2010-04-20" version="1">MTKSIAVIGEAVADAVAEPSATDGALRLEVRPGGGPANTAVALARLGSPTRFFGRLSGGVLGQLLRTHLEKSMVDLSGSVTERREATLAIAAIDDSGGAAYDFYIDGTADWQWNEDELAAAATSSVVHTGSLALVLSPGAEAITATLRKARPRATVSIDPNVRPAIASAERYRRGLDAWASLADILKLSQDDLDFTHPDTDARRLCERWHTLGCRLIVITRGAHGAVASLDGEWVKVAARRVHVADTIGAGDAFTAGLLHRLTVRGHHGGRLDRLDLATLTDALELAALVAARCCEVPGADPPWIGQLGPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBI6</accession>
    <name>D3QBI6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3198</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3198"/>
    <dbReference type="EnsemblBacteria" id="ADD42868">
        <property type="protein sequence ID" value="ADD42868"/>
        <property type="gene ID" value="Snas_3198"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3198"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_8_0_11"/>
    <dbReference type="OMA" id="TDWFLVM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="227"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="58"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="26730" checksum="89BB934B116C9574" modified="2010-04-20" version="1">MVLGVVGVLAVLAPLIADESGLDATKAEGGRLEGPSWRFWLGTDEVGRSVLVLVLWGARVSLLVGLAATVLSVGLGALVGLVAGHAGGGVSWVLMRVTDWFLVLPQLVLAIALATVLGPTQATIIVAIALTSWASTARLVRAATLSVSTRGHVERAKALGAGGWHVVRRHVLPGVLPLIAASATLQVASSVLAEATLSFLGLGDPGRVSWGTMLSRAHEAGSVSYGAWWYLLPPGLAIIAVVAAFTVCGRALESAFQEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBN3</accession>
    <name>D3QBN3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3245"/>
    <dbReference type="EnsemblBacteria" id="ADD42915">
        <property type="protein sequence ID" value="ADD42915"/>
        <property type="gene ID" value="Snas_3245"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3245"/>
    <dbReference type="HOGENOM" id="CLU_711537_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038332">
        <property type="entry name" value="PPE_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="388" mass="42561" checksum="01E889C0B4F5CA01" modified="2010-04-20" version="1">MGTYDSFTVDQLREIVDPDQPQTLRQQAEGWGKMAELLREYSLLLDERLRLVEHSWTGEAATMYFDEVRRVQEYIEDSAERATANCGLWCVIATMAGIAKHDVSHIHQLWKDLDAATDAVGLGFVAGVFGADEALEDFQRKPFDAASRQIMEVTMSAADESYARMRDFEEFEPPPSVDDSGLELQSVSTPAPPSGTAVAPPSTTVTATPAVPLGPTAPRPVVPSVIGSRPGMMPMARPMMGPGHTVPPVIGQRDGGSAQPGATGRLIGRDGVVRVTPDVDLRDPNASRAHYGGDDVNRGVIKSQNPQRVADEAQFKLEEEVRRLRERAYAHRVETLTADHSQYAIPGIVGDDSAWDTKAHDPGPVAFDVRRLRHRPVVDDWTLAVRRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBR4</accession>
    <name>D3QBR4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamate--cysteine ligase EgtA</fullName>
            <ecNumber evidence="2">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Gamma-glutamylcysteine synthase</fullName>
            <shortName evidence="2">GCS</shortName>
            <shortName evidence="2">Gamma-ECS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">egtA</name>
        <name evidence="4" type="ordered locus">Snas_5168</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2 3">
            <text>ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; ergothioneine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020374.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5168"/>
    <dbReference type="EnsemblBacteria" id="ADD44803">
        <property type="protein sequence ID" value="ADD44803"/>
        <property type="gene ID" value="Snas_5168"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5168"/>
    <dbReference type="eggNOG" id="COG3572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037109_0_0_11"/>
    <dbReference type="OMA" id="GLTFREW"/>
    <dbReference type="UniPathway" id="UPA01014"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052699">
        <property type="term" value="P:ergothioneine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02034">
        <property type="entry name" value="EgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017809">
        <property type="entry name" value="EgtA_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035434">
        <property type="entry name" value="GCL_bact_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011556">
        <property type="entry name" value="Glut_cys_lig_pln_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34378">
        <property type="entry name" value="PTHR34378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34378:SF1">
        <property type="entry name" value="PTHR34378:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017901">
        <property type="entry name" value="GCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR017901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="410" mass="44192" checksum="065EF9754C3D973C" modified="2010-04-20" version="1">MITIEDSAPATTPVTARLLQSRDEAAHYVARVCFKTGPPALTGVELEHTVHRLDDPAEPVGLTELRTALGPFAPITIDPRSPSRRLPGGGSVTVEPGGQVEISSLPHSGFPALHASVETDLRALEDLLRVHRLGIGDSGFDPRSRPGRLLRTPRYDAMARAFDQHGTPHGSSMMVATAGLQVCVDSGRDTELPSRWAALHAMGPVLLALFSTSRRPDAACVRMRTWLGMEPGRTHAVATDTGDPVSAWVDYVLRAPVLCVRRDGRPWFTPRDVSFEAWLGGALPDPPSLDDLELHLSMLFPPVRPRGYLEVRYLDTQPRRQWFAPVAVIGALLASASSIDKVRDLCAPVEGRWLDAATRGLADPDLRQAAAAVAALACDGLAATDVPEPVRHAVATIVDQRLAALHTQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBR9</accession>
    <name>D3QBR9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Membrane protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_5173</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020379.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5173"/>
    <dbReference type="EnsemblBacteria" id="ADD44808">
        <property type="protein sequence ID" value="ADD44808"/>
        <property type="gene ID" value="Snas_5173"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5173"/>
    <dbReference type="eggNOG" id="COG5305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024191_0_0_11"/>
    <dbReference type="OMA" id="LWFDELF"/>
    <dbReference type="OrthoDB" id="1664452at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="62"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD44808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="486" mass="52997" checksum="6FD284A1027B731F" modified="2010-04-20" version="1">MSPFVRKPWLLPFLAMLAIGGLGMWLPGLWADELATWGAIEESWSQLWALLSNTDAVNGGYYVVMKLWATVFGTSEVALRLPSLVAMAIAAGLTAAIGARLWTPRWGILAGVLFALLPMTSRYAAEARGYAFSMAFAVLASYLLVRLCQRPTTPPEPTDDQAPQPRQAPVWRLWLYYGLSIAAASVFHLMAILVLCGHGLMLLALNRHRWRGWLLAATASVAALAPLALLGATQISQTSWVLPLSFRALAHTPKDLFESRWTAAALAILIVIALWRSRSRPTIAVAAWALAPVLALMLAATVVDVWVPRYLLFLVPAWAVLGVRAVAGIRWKPTAMVMLAVAFVSGAGAQYDIRRSSGHAHDTLGAAALIETGYRDGDGLAVALNEPVVPWEARDLVARYLPPPLQPDDTFATTEQRTDGQLLASECPDPAHCLGDTPRLWVVRYENHTDPLTGIGGAKEQLLRDEFTVDQVWPLRGLTVALLIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBT4</accession>
    <name>D3QBT4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020394.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5188"/>
    <dbReference type="EnsemblBacteria" id="ADD44823">
        <property type="protein sequence ID" value="ADD44823"/>
        <property type="gene ID" value="Snas_5188"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5188"/>
    <dbReference type="eggNOG" id="COG5662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155928_0_0_11"/>
    <dbReference type="OMA" id="MSCGEPH"/>
    <dbReference type="OrthoDB" id="2036019at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024020">
        <property type="entry name" value="Anit_sigma_mycothiol_RsrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014295">
        <property type="entry name" value="Anti-sigma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02949">
        <property type="entry name" value="anti_SigH_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03988">
        <property type="entry name" value="antisig_RsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-HC2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="87" mass="9805" checksum="1564AE253A69A2F9" modified="2010-04-20" version="1">MSCGDPHEVDCREVLSEVYFYLDSECGDARRDLIKQHLAECSPCLAEYGIEQDVRALVHRCCSKDTAPQEVKARLREKLAKFDLGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBW8</accession>
    <name>D3QBW8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5223"/>
    <dbReference type="EnsemblBacteria" id="ADD44857">
        <property type="protein sequence ID" value="ADD44857"/>
        <property type="gene ID" value="Snas_5223"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5223"/>
    <dbReference type="eggNOG" id="COG4129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037626_2_0_11"/>
    <dbReference type="OMA" id="DWHEEAR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010343">
        <property type="entry name" value="ArAE_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06081">
        <property type="entry name" value="ArAE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="348" mass="37756" checksum="CA0ABB9FD6723F2F" modified="2010-04-20" version="1">MTRETLTQIAKMTLAAVAAWAIAEQIHPPQSFIAPYAAVFVISETVYRSLVQIGRQLVVVVLGIVLAFGVAATIQYSGAALAVAVAVGMLIGQWRRLGDDGIWVGTIALLMLTYGTADDPAYLYHRIVESLVGVSVGAVINILVFPPVQLRQAHRVVGQVSDMTIALLTAIGDGLRDGWDHETARSWQHRSQNLQRDARGAEESASRGYESTRFNLRRLTRSPRAATPHSYVAAVSVLSDVNTELRRIADALVTATDPHQPDGCPSGDFNGAFAELLDDLATALERYRHPLGPHDEQAEAGVRHGVRRAAQLRRQIIGDGGDHLGVQGMLVLAANRAFHRLRDENQDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBY8</accession>
    <name>D3QBY8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GH26 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5243</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 26 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020448.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5243"/>
    <dbReference type="CAZy" id="GH26">
        <property type="family name" value="Glycoside Hydrolase Family 26"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44877">
        <property type="protein sequence ID" value="ADD44877"/>
        <property type="gene ID" value="Snas_5243"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5243"/>
    <dbReference type="eggNOG" id="COG4124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038234_2_0_11"/>
    <dbReference type="OMA" id="HHEAEDQ"/>
    <dbReference type="OrthoDB" id="669354at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022790">
        <property type="entry name" value="GH26_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02156">
        <property type="entry name" value="Glyco_hydro_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51764">
        <property type="entry name" value="GH26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048428" description="GH26 domain-containing protein" evidence="4">
        <location>
            <begin position="33"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="GH26" evidence="5">
        <location>
            <begin position="8"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="353" mass="39679" checksum="A64650963BCFBCDF" modified="2010-04-20" version="1">MRPPLRKKRAIVIFTTMAAMIAAAAIGIPVFADTNDSGDRDCQVSEILVNECRPWLGARASDYPQADDSVTEQVAHHEERIGKPLDIVHTFAAEGQLPLRTKEERALANREDTYLYQNWKPAAKWKDAAGGDAEMDEHIDAAADNIAEVAPKKIFLTIHHEPENDVSSDSACDTKEDAAAGTAADYRDMWHNVRERFDAKGIDNVVWVMDYMNYEAWDCLVPKLYPGDEYVDWVMFNAYGDGNKADFAENVGRFYDLLNGLSSEEMDLKSKPWGIVEWGMSDSTQEQARDYYEQAATAVEKNQFPKLSSYMIFDSPGTHEDGGLRVGYDDKGKADAEEQKRYTEFANNPVFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC13</accession>
    <name>D3QC13_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RibD_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020473.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5268"/>
    <dbReference type="EnsemblBacteria" id="ADD44902">
        <property type="protein sequence ID" value="ADD44902"/>
        <property type="gene ID" value="Snas_5268"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5268"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_3_1_11"/>
    <dbReference type="OMA" id="GWYQNGD"/>
    <dbReference type="OrthoDB" id="1920912at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="3"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="194" mass="20808" checksum="404AF3518D254AF1" modified="2010-04-20" version="1">MAKVYTHMTMSLDGYIADPNDGIDELFEWYGAGEESVDSANEDVEFAVDSNSAELLREFTGSTGALVTGRRLFDLTDGWGDSHPVGAPVVVVTHQPPADTGKWPNTTFTDGVEAAIAAAKRIAGDEDVVIASASISAQALDLGLVDEVHVSQVPVLLGEGIPYFANLKNAPHRFDDPVVVQGKRATHLKYVVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC18</accession>
    <name>D3QC18_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative integral membrane sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5273</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5273"/>
    <dbReference type="EnsemblBacteria" id="ADD44907">
        <property type="protein sequence ID" value="ADD44907"/>
        <property type="gene ID" value="Snas_5273"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5273"/>
    <dbReference type="eggNOG" id="COG3300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061170_0_1_11"/>
    <dbReference type="OMA" id="ATIHYSP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005330">
        <property type="entry name" value="MHYT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03707">
        <property type="entry name" value="MHYT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50924">
        <property type="entry name" value="MHYT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="MHYT" evidence="3">
        <location>
            <begin position="8"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="337" mass="35567" checksum="D51322DEC6E712CE" modified="2010-04-20" version="1">MTHDHFAYGPINPIMGFGFALAGAFLGLTCMLHARRLPSGRGRIKWLAFASLAIGGTGIWMMHFIAMIGFSVPDGEVRYDIPITAASLVISIVSVAFGIFTVGLGKSSITKILIGGPLTGMGVVAMHYTGMAAVNLPGTIHYDPMWVAGSIAIAVVAATVALFFTTWVSGKGSLIGASIIMGIAVTGMHYTGMRSISVAIDDDILEVPGVDPLVLLIPILILATIVLIGLIVGVLGERDDMDELPERIVEAIERRRELTEETEAAQAADAATPSFWDPEPQPAAAEPAAVGQGRGGPTRFDAQAFGNRRLPQPRSNETAAPLWDTAEIEAGDPAPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUE3</accession>
    <name>D3PUE3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3288</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018527.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3288"/>
    <dbReference type="EnsemblBacteria" id="ADD42956">
        <property type="protein sequence ID" value="ADD42956"/>
        <property type="gene ID" value="Snas_3288"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3288"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="LEIAWLI"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="286"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="145"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="375" mass="40140" checksum="0D56A25070601DE5" modified="2010-04-20" version="1">MRPRLPHIPDRAKDWAIAIGVTVTVLVTALSQWESATVPHLAGVALLTASGLALVARRQTPILVLAVTGLCAVGYQATGFDVPAVAYVFAVYAAVRARHRLVTVLMSLAVLAALPLSIYLSGQHDTAEVFAQARGALEIAWLVAAAAAGEALRQAEQRADEAERTREETARRRANEERLHIARELHDSLTHQISVVKVQSEVAVHVARKRGEQVPDAVLAIQKAGREATRELRATLAALRDDDTTPPRGLDDVGDLVEQARAIGLAASLTIDGKPPPMPATVDRTIYRIVQESLTNIARHADTDTATVHIDCRPDTLRIRVDDDGKAAPDTATVPGVGLLGMRERVTALGGRLRAEPRGGGGFTVQAELPLEQTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV94</accession>
    <name>D3PV94_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1441"/>
    <dbReference type="EnsemblBacteria" id="ADD41147">
        <property type="protein sequence ID" value="ADD41147"/>
        <property type="gene ID" value="Snas_1441"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1441"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087580_2_1_11"/>
    <dbReference type="OMA" id="HEVTSWS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="192" mass="21907" checksum="FDD98FAF056B95D7" modified="2010-04-20" version="1">MTEKKTRHVTDAETLKAVTHPLRVKLLGTLRVLGPATASELGRRFGESSGSTSYHLRILAKYGFIEEDPEQPNARDKRWRSVHWGTSWSNAELQQDPAGAEAARAMRRRQLELLIESSERYEADIDSWGPVWQEAAGLSDHFARMKATTVNELRERVHALVREYAERDRDTKGTEMVQVYLGTFPLDESQIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVH0</accession>
    <name>D3PVH0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TsaA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the tRNA methyltransferase O family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018655.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3420"/>
    <dbReference type="EnsemblBacteria" id="ADD43084">
        <property type="protein sequence ID" value="ADD43084"/>
        <property type="gene ID" value="Snas_3420"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3420"/>
    <dbReference type="eggNOG" id="COG1720">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013458_2_1_11"/>
    <dbReference type="OMA" id="DWPLVGI"/>
    <dbReference type="OrthoDB" id="1535774at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd09281">
        <property type="entry name" value="UPF0066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023370">
        <property type="entry name" value="TrmO-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040372">
        <property type="entry name" value="YaeB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036413">
        <property type="entry name" value="YaeB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036414">
        <property type="entry name" value="YaeB_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818">
        <property type="entry name" value="PTHR12818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01980">
        <property type="entry name" value="TrmO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118196">
        <property type="entry name" value="SSF118196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51668">
        <property type="entry name" value="TSAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="TsaA-like" evidence="3">
        <location>
            <begin position="11"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00033753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="159" mass="17662" checksum="E66C65A335A9CC2D" modified="2010-04-20" version="1">MESTTPDVITTRPVAHVIGGRADPNDDDWNTETATIRFDATQFAPEALAGLDAFSHVEVIFRFHRTSPDRVNTGARHPRGNPDWPLVGIFAQRGRDRPNLLGVSRCQLLSVNGLDVHVRGLDAIDGTPVLDLKPYMTEFGPQGEVTQPAWATDLMRHYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVH5</accession>
    <name>D3PVH5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018660.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3425"/>
    <dbReference type="EnsemblBacteria" id="ADD43089">
        <property type="protein sequence ID" value="ADD43089"/>
        <property type="gene ID" value="Snas_3425"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3425"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_6_3_11"/>
    <dbReference type="OrthoDB" id="1772343at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="115" mass="12286" checksum="6C2BF4EE59C6AEA5" modified="2010-04-20" version="1">MTTAATSLSPEAQAFLKALASSTRQQIMFAFDGGSELTVGDVAKRLELAQSAASTHLATLRDAGILTSRRDWKTVYYRANPAGFLKSLDDLRDYLLACCPPDCAAPPDATAEDTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVK4</accession>
    <name>D3PVK4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018689.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3454"/>
    <dbReference type="EnsemblBacteria" id="ADD43118">
        <property type="protein sequence ID" value="ADD43118"/>
        <property type="gene ID" value="Snas_3454"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3454"/>
    <dbReference type="eggNOG" id="ENOG502Z9Y3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081273_0_0_11"/>
    <dbReference type="OMA" id="KWCVLAV"/>
    <dbReference type="OrthoDB" id="1287383at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025498">
        <property type="entry name" value="DUF4389"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14333">
        <property type="entry name" value="DUF4389"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="224" mass="25470" checksum="F3DFC62B57722793" modified="2010-04-20" version="1">MNGQTLTLTARSGESLSRWLWLVKWILLIPHYLVLLFLWTAFVVLTIVAYVAVLITGVYPRWIFDFNVGVLRWHWRVNYYGYAALGTDRYPPFTLADDPSYPARLDIARPERIARWRPLVHWLLAIPHLVLLNAFVAAPVWGDYDAPTRERAVVSIGVLGAAVLILGFGLLFTGRRLSGLYDLLLGLARWGYRVLAYVALMTDVYPPFRLDQGDAPTIVEHHGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVN4</accession>
    <name>D3PVN4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018719.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3485"/>
    <dbReference type="EnsemblBacteria" id="ADD43148">
        <property type="protein sequence ID" value="ADD43148"/>
        <property type="gene ID" value="Snas_3485"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3485"/>
    <dbReference type="HOGENOM" id="CLU_2865659_0_0_11"/>
    <dbReference type="OrthoDB" id="2075025at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="64" mass="7075" checksum="5E5EDD8448F57A70" modified="2010-04-20" version="1">MSTATITRAWTDVEFRAGLSTEELELVEHPAGDLDAELRELYIHEATAQSTNCTKWTGSPNCCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVP6</accession>
    <name>D3PVP6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3497</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018731.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3497"/>
    <dbReference type="EnsemblBacteria" id="ADD43160">
        <property type="protein sequence ID" value="ADD43160"/>
        <property type="gene ID" value="Snas_3497"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3497"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_0_11"/>
    <dbReference type="OMA" id="PLRIGTF"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="307" mass="33020" checksum="2E97917781D33359" modified="2010-04-20" version="1">MFEVRRLRLLRELSVHGTIAAAARVCALTPSAVSQQLALLEREARTPLFIRDGRRLRLTKAARILVEHTERILTELEQAQAAVAALARSISGTMRLAAFPSAAGNIAASAIAACQAAHPDLRILLEENEPDASLTDLRAQRIDAALVYEYNLLPRLAEPGIELSPLLQEPLLLAVPPHRTGDGPGSLAEYHDDRWIAPHSDTALRTVLERACHAAGFTPRLDYTSDDFTVIMALVRAGLGVSLIPHSVVEPLATEVRLHPVSDFPLTRTVSVAVRTGSGTDPAIEALVAALRRAAGPGANPYHVVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVS3</accession>
    <name>D3PVS3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5412</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5412"/>
    <dbReference type="EnsemblBacteria" id="ADD45044">
        <property type="protein sequence ID" value="ADD45044"/>
        <property type="gene ID" value="Snas_5412"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5412"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1894909_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="87"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="155" mass="17107" checksum="40A2E8458F3C73A0" modified="2010-04-20" version="1">MTTVNAPVPTYALAKRQPAATDPKVWTRLGVHITDLHNEAQGLRRPERLTRAALGAVTLLRSLGVRIELPSGELPTRDLPSALSRPKPSGTLTLTDREREVLGGMAEGKSNAEIGRELFVTEDTIKTHARRLFRKLDARDRAHAVSQGFRLELLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVT6</accession>
    <name>D3PVT6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5425"/>
    <dbReference type="EnsemblBacteria" id="ADD45057">
        <property type="protein sequence ID" value="ADD45057"/>
        <property type="gene ID" value="Snas_5425"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5425"/>
    <dbReference type="eggNOG" id="ENOG502ZA7W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055770_0_0_11"/>
    <dbReference type="OMA" id="YLIKRMP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009553">
        <property type="entry name" value="DUF1173"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06666">
        <property type="entry name" value="DUF1173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="451" mass="50597" checksum="0F5E2756417CF9C2" modified="2010-04-20" version="1">MHFGTTDGSNTSPNVRVGNRSMSLDDLYRDRARCARILASARAEDGHAWCECNCPQSKLVIRCRQGVWHLARWPGDRIGHAANCPFRGIDPGLTGRAAFSESAIQESRDGVHLRIATSLTTDLGTRSKPGLGDHHRGGGSNRHRLTLLGLLEYLWEESRLNEYRSGSRLWWGRCHHALVSQVENSFLGDQPLSEVMYVVPPFRKESAANNEATWNAFAAGLGSKNRRSRLGIVLGEFKDAAATSRGYRIRLRNFRKPIFVTRKLWDTLTMRFQSAFTSQMTAQGRQVGLWVVDKATRGYLRLSTAGIMATTQSWIPVDSGYELTMANALADANRSFLKPLRYQHCDVVLPDFVITDTNPRTYIEVWGIVGRESYERRKQEKQDYYKQRGLQLIEWNVSESIPEVPRLLSCRVSSRLSTEDAVTSSSGQFVAGLSSSDSHGNEQFPQATPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW00</accession>
    <name>D3PW00_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5490</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EccE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020692.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5490"/>
    <dbReference type="EnsemblBacteria" id="ADD45121">
        <property type="protein sequence ID" value="ADD45121"/>
        <property type="gene ID" value="Snas_5490"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5490"/>
    <dbReference type="eggNOG" id="ENOG50331Q0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043760_0_0_11"/>
    <dbReference type="OMA" id="RITWIAL"/>
    <dbReference type="OrthoDB" id="832050at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021368">
        <property type="entry name" value="T7SS_EccE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11203">
        <property type="entry name" value="EccE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03923">
        <property type="entry name" value="T7SS_EccE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="423" mass="44756" checksum="5758A2A449003385" modified="2010-04-20" version="1">MTMVQHQAPARGTAVVAERRRRPEEPVAFSARNNGRLGPFTLLHLFAIEAAIGVGAGVYTANMGKTMQQALPWYIGGGVVILLLLIPTFLRGGGVWLYQAIPMRRRLAGRRRQAGLSKEPLHGIAPDLGIVGIVERDTDIGIGHDEGGWFAALAMGGVDGVTEPVPLDRLARLFTESGVPVSAIQVVGHTVPIGLVGHDGSPASMSYQELLGGLPAVVHHTSWLAVRMNTEDAMDAAADRGGDVEGVHKALAVTVSRVGKLLRNAGVENRVLDADGLRDTLRESLGLSRTDIPAGQIRCGESWSQWQGDGLQHVTYRVVRFPTDEGTLRHLIDVLAAVPAVFNTASVILRPGVVEARDPDGRPTGRRVEVECLIRITGDAQTSAAGQARVRGAAESLGAKLERLDGEQGPATYASAPTGGGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWH2</accession>
    <name>D3PWH2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NB-ARC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3532"/>
    <dbReference type="EnsemblBacteria" id="ADD43194">
        <property type="protein sequence ID" value="ADD43194"/>
        <property type="gene ID" value="Snas_3532"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3532"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="147"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="827" mass="90382" checksum="B6B544CCF105FABA" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWZ1</accession>
    <name>D3PWZ1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pentapeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020786.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5585"/>
    <dbReference type="EnsemblBacteria" id="ADD45215">
        <property type="protein sequence ID" value="ADD45215"/>
        <property type="gene ID" value="Snas_5585"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5585"/>
    <dbReference type="eggNOG" id="COG1357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100224_0_0_11"/>
    <dbReference type="OMA" id="LPWDEMP"/>
    <dbReference type="OrthoDB" id="985095at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="101"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="258" mass="29474" checksum="BCFBEC6C99D96884" modified="2010-04-20" version="1">MNEFRGQDLSGARFEDVMLTGAEFHDIDLSDARFRLVSLKGASIRGADLRDLDLSGWIGNLRVNGVDVAPLVEAELDRRHPERAKMRPTDAAGYREAWRILERLWGQTIERARGFEPWQLHESVDGEYSFIETLRHLNFAPDAWVGRAVLGDPTPWHPLDLPHDEMPDEPSVPRDRDARPTLEEVLAVRRERVAMVRRVLDELTDEKLVTATEPVTEPGYPESQSFPMTRCLGAVINEEWEHRLYAERDLDVLAGKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX13</accession>
    <name>D3PX13_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5607</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020808.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5607"/>
    <dbReference type="EnsemblBacteria" id="ADD45237">
        <property type="protein sequence ID" value="ADD45237"/>
        <property type="gene ID" value="Snas_5607"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5607"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_2_2_11"/>
    <dbReference type="OMA" id="ATSWIFT"/>
    <dbReference type="OrthoDB" id="1694312at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="68"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="268" mass="29111" checksum="C9BE1F07322C61A3" modified="2010-04-20" version="1">MSVATTNQRRRRRIRDANLPYQLATLVVFAAAWEIYARVSGGLLIPSFTETAVATVELLGTAELWRAVYVSNQALVLGFGAAVVIGIPVGILLGRFRLLERYLDVYLNILLITPMAAIIPLLVMSVGFGLASRVILVAVFAIVMVVVNARTGVRQVDPALIEMARSFGASERQIWTRILLPGALPAIMTGIRLGIGRAITGMVIVELLMVSTALGGLILEYRGLFKAPLLYGTIVIILAEAILLISVARWGERKLTRWAETTTARSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX49</accession>
    <name>D3PX49_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5643</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020844.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5643"/>
    <dbReference type="EnsemblBacteria" id="ADD45273">
        <property type="protein sequence ID" value="ADD45273"/>
        <property type="gene ID" value="Snas_5643"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5643"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="AAYSPYR"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="4">
        <location>
            <begin position="260"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="235"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="478" mass="51234" checksum="278F243E0F5E3B42" modified="2010-04-20" version="1">MPCEPLVSENGPVFTIPAVKHPREWFSSVTRPSGPLPRPSRRAYAFDVALVLLIAVISIGYIDDHTPVRHINGIPRTIEWDEWTGAIVFLAVAMPALIWRRRFPLTVLWLVAAATVLPQHELPQLAFYLCVIAGYSAAAYSPYRIPTMLSLAAAVVAVASLTPNVLQDVPMGNKAPSTIDQTESEDVFAPQEHDMATRPQSDGASSVVPSEYVAPLILIPVVLAASAMRVWKHRVSESRTRLSTLEKERAEELRRAAEQERARIARELHDVVTHNVSVMVIQTGAARKVMDASPDQAKAALLAVEAGGRAAMSELRHVMGLLTMDDAASAGRAAGSSGDDPDALSLTPQPSLERLESLVERVRGSGTDIALTITGSARPLPSGIELAAYRVVQEALTNTVKHAAGATARITVDYQDDRLAVKVTDSGGTPTSAATTGNGHGLLGLRERLAVYGGTLRCGPTPLGGYRVEAVIPLEDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXD4</accession>
    <name>D3PXD4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1698</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016968.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1698"/>
    <dbReference type="EnsemblBacteria" id="ADD41397">
        <property type="protein sequence ID" value="ADD41397"/>
        <property type="gene ID" value="Snas_1698"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1698"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043648_0_0_11"/>
    <dbReference type="OMA" id="SMPPFAW"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014305">
        <property type="entry name" value="RNA_pol_sigma-G_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02960">
        <property type="entry name" value="SigX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="19"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="136"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="35741" checksum="FF9D27976056E110" modified="2010-04-20" version="1">MAEPRPATTIAGLTDELETLRAPLTRYCYRLLGSAADTDDAVQETLIRAARNVGRYDPSRARLTTWVHRIATNICIDMLRGAKRRALAMDLGPATETGELGIPLPPERWVEPMPDRRLFGTADPGDIVAERETVRLAFIALLQRLSPRERAILVLRDILKFSARETAEILDSTVAAANSALQRARASLAADRPRPADVLDPEGPEQRELLARYVAAFESHDVAAMTALLREDAITSMPPFTWWLRGGERIAALMAFSDVCAEDRLLVTAVNGSPGFGQYRPDEAGVLRPFAIILAEPCGGRIAQLVTFLGSAARFGEFGLPEVLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXM5</accession>
    <name>D3PXM5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3698</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018926.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3698"/>
    <dbReference type="EnsemblBacteria" id="ADD43355">
        <property type="protein sequence ID" value="ADD43355"/>
        <property type="gene ID" value="Snas_3698"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3698"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="WGKQLIV"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="337" mass="35792" checksum="F3304910025FADEB" modified="2010-04-20" version="1">MGVVSVKDVAALAGVSAGTVSNVLNNPERVSAATIDRVQRAVDQLGYVRNGAARQLRAGHSRSIGLIVLDVGNPFFGELIRGAEDKAVEAGLTVLVSDSREHPDREKTQVELFEEQRVRGVLLSPVVEAWPAVERLRSRGIPVVLVDRALSDTSVSSVSVNDVAGGELAVAHLIEQGRRHIAFVGGPMNIRQVTDRLEGARKAVSEHSGVAFEVIETRELTVPAGLDAAARLATREAADRPDAVFAANDLLAFGVLQGLIVNGGLRVPDDLMLVGYDDIDFAQAAIVPLTSIRQPARRIGETGIELLLAEAEGSGDFTPRQVVYQPALVKRASTASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXV9</accession>
    <name>D3PXV9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EndoU_bacteria domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5658</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020859.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5658"/>
    <dbReference type="EnsemblBacteria" id="ADD45288">
        <property type="protein sequence ID" value="ADD45288"/>
        <property type="gene ID" value="Snas_5658"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5658"/>
    <dbReference type="eggNOG" id="ENOG5033K6V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1389481_0_0_11"/>
    <dbReference type="OrthoDB" id="1431104at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029501">
        <property type="entry name" value="EndoU_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14436">
        <property type="entry name" value="EndoU_bacteria"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048684" description="EndoU_bacteria domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="EndoU_bacteria" evidence="3">
        <location>
            <begin position="118"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="196" mass="20776" checksum="C45095767F6C27DC" modified="2010-04-20" version="1">MIGKLLLLLTAVGMSAMAKGGGGKGPRRPKGGRGGGGKSFGLTADEVDMLLNKSTTSAPPPAPSRKSGGKNGWDDRQPNEPDPRKTMPNLGDTTQRRGHILDGDKNDPTSGGHRYGTNRPGKTEFPKHWTDDQIMDMVNDVARNPDSQPLPRPNGAGYEVQGQRAGVTIRVILNADGTVWSAHPLDGGLGVKKNPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXZ4</accession>
    <name>D3PXZ4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutaredoxin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5693</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020894.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5693"/>
    <dbReference type="EnsemblBacteria" id="ADD45323">
        <property type="protein sequence ID" value="ADD45323"/>
        <property type="gene ID" value="Snas_5693"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5693"/>
    <dbReference type="eggNOG" id="COG0695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125054_2_1_11"/>
    <dbReference type="OMA" id="YWEQIPV"/>
    <dbReference type="OrthoDB" id="2001991at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008554">
        <property type="entry name" value="Glutaredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05768">
        <property type="entry name" value="Glrx-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="79" mass="8754" checksum="0A985837F2E8F085" modified="2010-04-20" version="1">MPRLRLLTTKHCHLCAAAREALGRVAATAGVDWDEVDVADDVALAREYGDRLPVVLLDGREHGYWTVEEARLLRDLNAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXZ8</accession>
    <name>D3PXZ8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uroporphyrinogen III synthase HEM4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5697</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020898.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5697"/>
    <dbReference type="EnsemblBacteria" id="ADD45327">
        <property type="protein sequence ID" value="ADD45327"/>
        <property type="gene ID" value="Snas_5697"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5697"/>
    <dbReference type="eggNOG" id="COG0007">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1587">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011276_6_0_11"/>
    <dbReference type="OMA" id="VTGRYEW"/>
    <dbReference type="OrthoDB" id="1185397at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033014">
        <property type="term" value="P:tetrapyrrole biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="5">
        <location>
            <begin position="12"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="HEM4" evidence="6">
        <location>
            <begin position="260"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="527" mass="55794" checksum="8A33C1DFF82F71BB" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYC2</accession>
    <name>D3PYC2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017060.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1792"/>
    <dbReference type="EnsemblBacteria" id="ADD41489">
        <property type="protein sequence ID" value="ADD41489"/>
        <property type="gene ID" value="Snas_1792"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1792"/>
    <dbReference type="eggNOG" id="COG3591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050832_0_0_11"/>
    <dbReference type="OMA" id="VGTFFWT"/>
    <dbReference type="OrthoDB" id="1468733at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048081" evidence="1">
        <location>
            <begin position="27"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="32349" checksum="63DC2B54DFB0341D" modified="2010-04-20" version="1">MRAARIAALSLIGAAVAIVGPATAVADPATGDGAAVNDTTSDGVTDYWTSSRMENAVSLDINLDPGTLTDDVKAGAEVEIDPTLADSTGDPWTGGGDVVNTAGRVFFKFDGKDASCSGNAVTSDNGNTVLTAGHCVKYQGAWHTDWVFVPGYHDGQAPFGEWPASKTLTTPQWEADEDMNYDVGAAVVEPQGGKSLTDTVGGQGVAFNGEYNQKMYAFGFPAADPYDGEKFIYCGGTSSKDVLLTQDHSLPCDMTGGSSGGPWFREFDEATGTGLQSSVNSFGYKFLPNVMFGPYFGDDAKALYDKAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYR3</accession>
    <name>D3PYR3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class I and II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019067.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3840"/>
    <dbReference type="EnsemblBacteria" id="ADD43496">
        <property type="protein sequence ID" value="ADD43496"/>
        <property type="gene ID" value="Snas_3840"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3840"/>
    <dbReference type="eggNOG" id="COG0436">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038911_0_0_11"/>
    <dbReference type="OMA" id="IFTPYIE"/>
    <dbReference type="OrthoDB" id="554560at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022518">
        <property type="entry name" value="Aspartate_4-decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03801">
        <property type="entry name" value="asp_4_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="185"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="548" mass="61377" checksum="F97709F762502876" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYT9</accession>
    <name>D3PYT9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3867"/>
    <dbReference type="EnsemblBacteria" id="ADD43522">
        <property type="protein sequence ID" value="ADD43522"/>
        <property type="gene ID" value="Snas_3867"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3867"/>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_10_1_11"/>
    <dbReference type="OMA" id="GIWMFGG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="1">
        <location>
            <begin position="47"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="316" mass="34154" checksum="64DD0EB487D65748" modified="2010-04-20" version="1">MVAAAVLLTACGTSEPGADSEKDDKGGPVTVTDARGKEVKLKSPADRVVSLEWAETEMLVSLGVMPVGVAQSKEFGTWNTAVKLDKKVKDVGDRNEPSEDAISGLNPDLVITTSDRPDSTLKQLEKSVPVLVVKGSDAKSGNLKRMESDLDMIAEAVGRTDEADTLMEDFESKLAEGKKALGDAADTPFLMADGWDADGKISIRVHSTGSMYDEVATGLGLKNAWTKKVAYDKVWGLDTVDVEALSYLEDKKLKFMYDDSGKFGVFTKKLKGNKIWDSLTFVKDGETHKLPDGIWMFGGPKSGEQMIDAIVEVYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYZ0</accession>
    <name>D3PYZ0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5789</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5789"/>
    <dbReference type="EnsemblBacteria" id="ADD45419">
        <property type="protein sequence ID" value="ADD45419"/>
        <property type="gene ID" value="Snas_5789"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5789"/>
    <dbReference type="eggNOG" id="COG0637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_13_2_11"/>
    <dbReference type="OMA" id="MDVYGFT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="248" mass="26739" checksum="DB260B6FBD40E64D" modified="2010-04-20" version="1">MTSRRLRRTRGGRFGDDGRVPILDTGSEHTVVPTPKLVIFDNDGVLVDSERLSNMVFAEWITENGLPTSYEESVEYYMGKRTTDCAAEIERRLGRELPADFVAVYESRCNDLLSRELTTVDGVEELLDRLDGNATPYCIASSGTPDEIALRLATTGLDARFDGNIYSGTQVPNGKPAPDLFLHAAARMGVDPSDCVVIEDSPAGITGAKAAGIRVIGHAALLPPHRLREAGADEVVAGMREVGPLLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ33</accession>
    <name>D3PZ33_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4097 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021033.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5832"/>
    <dbReference type="EnsemblBacteria" id="ADD45462">
        <property type="protein sequence ID" value="ADD45462"/>
        <property type="gene ID" value="Snas_5832"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5832"/>
    <dbReference type="eggNOG" id="COG3595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081211_1_0_11"/>
    <dbReference type="OMA" id="RAHTSFG"/>
    <dbReference type="OrthoDB" id="1059710at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4097" evidence="1">
        <location>
            <begin position="134"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="229" mass="24438" checksum="3FA887012D8A4E10" modified="2010-04-20" version="1">MPTFETPKPVNVEITVMLGNVTVTAEDRTDTTVTVTPTNPDNEADVKAASETHVELSGDTVTIKGLKFRKYIGPTKNNLSVDISVAVPTGSSLFAKAYGSVLNLTTSGRLDRCEFRTGAGRLVLDHVGPMRLRTDGNIVIDRADGDVDATTSTGNIRISEVKQGTVELKTSFGEIEVGVPEGTAALLDLQTSLGSIRNHLTDTSEPAPDDRTVKVRARTSGGDIEIRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ41</accession>
    <name>D3PZ41_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021041.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5841"/>
    <dbReference type="EnsemblBacteria" id="ADD45470">
        <property type="protein sequence ID" value="ADD45470"/>
        <property type="gene ID" value="Snas_5841"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5841"/>
    <dbReference type="eggNOG" id="COG2270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052021_0_0_11"/>
    <dbReference type="OMA" id="MRFCYGA"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="436" mass="47181" checksum="5B03811E2CB2E1DB" modified="2010-04-20" version="1">MERHHVRAIVRRRDFRRLLTARVTSQLADGLFQAGLAVSVFFNPTKQIEPMAYAVAFAMLVAPYSVLGPYVGVFLDRWSRRDILAVSNLVRALLVIPAAAFILGDGPEWSFGVFALLIITINRFVLAGLSASQPHVVEPPHLVTANSLATTLGTICYGTGLGLSYLVIRLTESFVPGAETLPYGATASLAVPLYAISALVAWRSFSSTQLGPDETERATDRLLAAIIATAKGMVTGFRHLWQRRGAAYVMSVQAGHRALYGVLAVFTLAIFRGYFHDPAEAHFGDTLAWLASIAVAGQAGSFLAAVVTPGISRRFGPGRWVASLMTLMIAVVASLGLNLVEPMFVAGTFLVNIASQSTKIVVDTSLQTSCDDEYRGRLFSLNDTVFNFTFIVGMFTGAALLPGDGMAPWLLFATAGGYVLLAGWYWLVSRRHPPYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ49</accession>
    <name>D3PZ49_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021049.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5849"/>
    <dbReference type="EnsemblBacteria" id="ADD45478">
        <property type="protein sequence ID" value="ADD45478"/>
        <property type="gene ID" value="Snas_5849"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5849"/>
    <dbReference type="HOGENOM" id="CLU_135691_0_0_11"/>
    <dbReference type="OMA" id="ETCHALQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="137" mass="14962" checksum="429F8C28CFC898B1" modified="2010-04-20" version="1">MDVVRIGVISVALVSLASLPCLIAWVIVNADDAADRAGKTVARLRPHTPAHPPIEDTAARLRELAAELTDTPRDALLRRAELTDRYDLTLRQACATMDIPQYLTRLTGDDADVERLRLEGELEAVGLVLRGPARGCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZH7</accession>
    <name>D3PZH7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017222.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1955"/>
    <dbReference type="EnsemblBacteria" id="ADD41651">
        <property type="protein sequence ID" value="ADD41651"/>
        <property type="gene ID" value="Snas_1955"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1955"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_24_2_11"/>
    <dbReference type="OMA" id="HRPRKEM"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="202" mass="21839" checksum="30C2366D0AA51145" modified="2010-04-20" version="1">MAKPTAPGKAEAAAQTRDRLVSRARSLFARRGYADVGLTEIVAHAGVTKGALYHHFDSKADLFRAVIAQVHDEVGERVAAAAEASEDPWEQLLHGCDAFLRASVDPVTQRILLIDGPAVLGWREWKALDASASERHLTEMIEELIEEEVLPTQPVKPLVHLLSGAMNEAALWLAHASGPDDIAATMRALTAMLDGLRRPGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZP6</accession>
    <name>D3PZP6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Coproporphyrinogen III oxidase</fullName>
            <ecNumber evidence="6 12">1.3.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Snas_3928</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 12">Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>coproporphyrinogen III + 3 O2 = coproporphyrin III + 3 H2O2</text>
            <dbReference type="Rhea" id="RHEA:43436"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="EC" id="1.3.3.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:43437"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Porphyrin-containing compound metabolism; protoheme biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.15" evidence="6 12"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019154.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3928"/>
    <dbReference type="EnsemblBacteria" id="ADD43583">
        <property type="protein sequence ID" value="ADD43583"/>
        <property type="gene ID" value="Snas_3928"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3928"/>
    <dbReference type="eggNOG" id="COG1232">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009629_3_1_11"/>
    <dbReference type="OMA" id="EHNQAVQ"/>
    <dbReference type="OrthoDB" id="630753at2"/>
    <dbReference type="UniPathway" id="UPA00252"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004572">
        <property type="entry name" value="Protoporphyrinogen_oxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00562">
        <property type="entry name" value="proto_IX_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0274">FAD</keyword>
    <keyword evidence="8 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 12" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="10 12 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="13">
        <location>
            <begin position="13"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD43583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="477" mass="48890" checksum="983F9CDFA79A7383" modified="2010-04-20" version="1">MTPRHVVVVGGGIAGLAAAQRLRELGGPELRITVVEQAPRLGGKIRTGELAGVPVETGAETFLVRRPEAKALAETVGLGARLVHPAAAPAALVIDDELRDLPRRTVMGVPARADDVAGVLSPAGRERLEQEPVGDGPILGDEDVTVGALVRKHFGDEIVDRLVDPLLGGVYSGRADGLSVDVTVPQLAAAARRHDTLAGAVADCLPPVAGAPSAGSAAFGAAASGSASSVPPVFGSVEGGLSRLVEATATAAAAEIVLGKPVRELRRTPEGWRCVAGDTRTPRVIECDALVLATPARPAARLLADVEAAAAAELGVLDYASIALVTLALGGVELPQRSGFLVPATEGRTIKAATFFTRKWPHLARPGLSLVRVSLGRYGEEQVLQRDDAELADIAHAELSAVLGMELPRPRAVAVDRWGGGLPQYSAGHADRIRRARAALAEHPIALAGALADGVGIPACVASGRAAAEAVHATLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZQ2</accession>
    <name>D3PZQ2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3936</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019160.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3936"/>
    <dbReference type="EnsemblBacteria" id="ADD43589">
        <property type="protein sequence ID" value="ADD43589"/>
        <property type="gene ID" value="Snas_3936"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3936"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_3_0_11"/>
    <dbReference type="OMA" id="ANHAIVD"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="2">
        <location>
            <begin position="299"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="455" mass="48801" checksum="1F76581A65DBF285" modified="2010-04-20" version="1">MTTIAIIGGGNGGLCLAQGLARAGIDFTVYERDATVTSREQGYRVHIDPNGSAALAECLPEPLWNAFVATAGEAGTAGFGFLTEKLAPLCLVEPEIFRGGHDDPASGHHAASRVTLRQILLAGLGDRVRFGKEFVDHEQLDDGRVRVNFADGTSAEADFVVAADGANSRLRRRVLPAASRVDVGAMGIGGKLPLAGADWLPHHLAAGLNVIMPPRDFLFTAAFQRRHTETDARALLAEDIAAAGLDVAELFRHFENTDYMMWAFVLPTGTVDIDSPGTVLRDLVLERARDWDERLRRVLAETAPDTINAFAFRAATKVKPWPTGNITLLGDAIHSMPPTGGVGANTALRDAALLCRALTDVDRGRSSLREAVAGYEKEMLKHGFAAVDTSVTRARQALSGRIARLGGRTFMRVCGAVPPLRRAVFKTRWTEPPRTGSDAPPATSDTDDGRIASRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q074</accession>
    <name>D3Q074_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase involved in chromosome partitioning-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5977</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021174.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5977"/>
    <dbReference type="EnsemblBacteria" id="ADD45603">
        <property type="protein sequence ID" value="ADD45603"/>
        <property type="gene ID" value="Snas_5977"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5977"/>
    <dbReference type="eggNOG" id="COG0455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003609_6_0_11"/>
    <dbReference type="OMA" id="TMTTICL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="2">
        <location>
            <begin position="295"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="542" mass="58666" checksum="F0DF7CFD69DB6350" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q090</accession>
    <name>D3Q090_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021190.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45619">
        <property type="protein sequence ID" value="ADD45619"/>
        <property type="gene ID" value="Snas_5993"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5993"/>
    <dbReference type="eggNOG" id="ENOG5033HKJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183103_0_0_11"/>
    <dbReference type="OMA" id="FAVWLAC"/>
    <dbReference type="OrthoDB" id="2092959at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="75" mass="7953" checksum="9A23CC07C8CB768D" modified="2010-04-20" version="1">MKFLVIQICGMVVLAIGGQGAIRLLIDHGDRGLLDWLPGGFAVTLAGYVLVAIIGLLLGGWGADKHKKQQQAERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0M5</accession>
    <name>D3Q0M5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipase D/Transphosphatidylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017332.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2067"/>
    <dbReference type="EnsemblBacteria" id="ADD41761">
        <property type="protein sequence ID" value="ADD41761"/>
        <property type="gene ID" value="Snas_2067"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2067"/>
    <dbReference type="eggNOG" id="COG1502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_507969_0_0_11"/>
    <dbReference type="OMA" id="FFTDWRG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PTHR18896"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="370"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="536" mass="60287" checksum="1517672426203EAD" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Q6</accession>
    <name>D3Q0Q6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Activator of Hsp90 ATPase 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2098</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017363.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2098"/>
    <dbReference type="EnsemblBacteria" id="ADD41792">
        <property type="protein sequence ID" value="ADD41792"/>
        <property type="gene ID" value="Snas_2098"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2098"/>
    <dbReference type="eggNOG" id="COG3832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122733_1_1_11"/>
    <dbReference type="OMA" id="TEIHWSA"/>
    <dbReference type="OrthoDB" id="1719670at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="153" mass="16776" checksum="B9C6BD0DCE7650CB" modified="2010-04-20" version="1">MTSSNYDVTATTTAPPAVVWRLLLDARTWPQWTPIDELVVDRSTGLGPDNGSTQVGSVRAFRVGEGVTGERVTELVDERRFSYEDAFIDVMSDYQASIELTPTPTGTTIRWHGTYTPAPGMESVLPDYLRDFMQQMADGLATHAASLTKTTDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0V2</accession>
    <name>D3Q0V2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019273.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4050"/>
    <dbReference type="EnsemblBacteria" id="ADD43702">
        <property type="protein sequence ID" value="ADD43702"/>
        <property type="gene ID" value="Snas_4050"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4050"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_5_2_11"/>
    <dbReference type="OMA" id="HEPDIIR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="24670" checksum="8CF9739B5DABE223" modified="2010-04-20" version="1">MTPSGPTTRRDPLSKESVLRTAIALADETGDGVPSMRGLAKRLGVEAMALYHHFRNKDDILDGMVDLVFAEIELPGDEDWQPAMRRRATSMRDALTRHPWAISLMDSRKNPGPATMRHHDAVIGCLRNGGFTIAGAAHAFSVLDAYIYGFTLQHLSLPFTSSDELEDVADAILEQLPREEYPHFAEMFGHVMKPGYAVTDEFDIGLDLVLDGLRRHRDGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q137</accession>
    <name>D3Q137_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular ligand-binding receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019358.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4136"/>
    <dbReference type="EnsemblBacteria" id="ADD43787">
        <property type="protein sequence ID" value="ADD43787"/>
        <property type="gene ID" value="Snas_4136"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4136"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_1_2_11"/>
    <dbReference type="OMA" id="SADEDMI"/>
    <dbReference type="OrthoDB" id="538961at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048784" evidence="1">
        <location>
            <begin position="24"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="35"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="399" mass="42844" checksum="058B5B7A48513B51" modified="2010-04-20" version="1">MKYRAGRKIVTAACGLLLLTSLASCSVNDKKSPGTVDVGLLTPLSGALKEVGADAKDAFDRYIDVNDGKLGGRKINLSIRDEGDDPKTSLPSAKKLMQDDNVDVIVGAASSANYIAVAPEATKAEVPLLGYGGQPPLDDAGIDFKWLWQTSFSTSQLGASIAPYIKDKVDGSVYTIAPDYEGGKAVMGSFIKPFMEAGGKLANAEKEPAWTPWPKTMDFSKYFEEAAASDAKAIFAYYGGAPAIEFVKQYAKSPAKDIPLYGAFLTEGAVLEAQGEAAEGVQTVMNYAPDIDNAANRRFVSEWSEINSDRPTSLYSMVGWDAALVLDQAISRIPLDEEVTPAKINKAMGELGTINSSRGSWQFDEELHIPIQRWYLRTVAKDGPSLTNVVTEDLDTIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q192</accession>
    <name>D3Q192_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021243.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6048"/>
    <dbReference type="EnsemblBacteria" id="ADD45672">
        <property type="protein sequence ID" value="ADD45672"/>
        <property type="gene ID" value="Snas_6048"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6048"/>
    <dbReference type="HOGENOM" id="CLU_647063_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="424" mass="45526" checksum="001D0A934B61F51F" modified="2010-04-20" version="1">MGELSAEQIWQWSQVAEANAPIWSRQAWGAWRLGNSLDVKNQEMSETGRFGFDAADAKGHLGAALGEAVTKLRAHMSGYAANTGELQAAMERVAEARGDTHTQLERLWKRYEATTDKVTRAEIEQEMRARYSKFADDYRGEAASVKDFDAYSGVRKPVDSPTHNSDRLGDNGTTYSGGRGWPSREGAGDSGAHQSGGYHGDRGRSVASFGPELQTTAPAPTATPTPTSATFHVPTQPTLPPVIGGRTGLPIHGSPQPAPRPGPSGLVNPVNHGARPTPALPPTRPTTVTPQPIQSWRGKVSPTSATPPTRQSANPRPTTGSRQPAKPATPRFRREGGIRASIQGPQAKPGTTRTPVRASGEPEATLSADGERTTEWTVDRATVAPVIRGHRGHGGHEHDPGTVAARDGMRQRKPRVYFEHNEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1A0</accession>
    <name>D3Q1A0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-demethylubiquinone-9 3-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021251.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6056"/>
    <dbReference type="EnsemblBacteria" id="ADD45680">
        <property type="protein sequence ID" value="ADD45680"/>
        <property type="gene ID" value="Snas_6056"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6056"/>
    <dbReference type="eggNOG" id="COG3865">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_22_1_11"/>
    <dbReference type="OMA" id="MVEFELF"/>
    <dbReference type="OrthoDB" id="1889762at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06588">
        <property type="entry name" value="PhnB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009725">
        <property type="entry name" value="3_dmu_93_MTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028973">
        <property type="entry name" value="PhnB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06983">
        <property type="entry name" value="3-dmu-9_3-mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021700">
        <property type="entry name" value="3_dmu_93_MTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="3-dmu-9_3-mt" evidence="1">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="157" mass="17749" checksum="0215BDCEE4F9A1F0" modified="2010-04-20" version="1">MKEVTPFLWFDTQAEEAATFYTSLFDDGKITKVLHYGSAGPGESGSVMTVDFELAGQKFMALNAGPQYRFNESVSFLIHCDTQEEVNRYWSQLTEGGEPRPCGWLKDKYGLFWQIVPKLLFTLRDDPDQVKGQAVMAAMLNMGKIESAELQRVYDNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1C4</accession>
    <name>D3Q1C4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ExsB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021275.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6080"/>
    <dbReference type="EnsemblBacteria" id="ADD45704">
        <property type="protein sequence ID" value="ADD45704"/>
        <property type="gene ID" value="Snas_6080"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6080"/>
    <dbReference type="eggNOG" id="COG1606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061181_2_0_11"/>
    <dbReference type="OMA" id="DKPAQPC"/>
    <dbReference type="OrthoDB" id="846643at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01990">
        <property type="entry name" value="Alpha_ANH_like_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005232">
        <property type="entry name" value="LarE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43169:SF2">
        <property type="entry name" value="PTHR43169:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006661">
        <property type="entry name" value="PP-lp_UCP006661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00268">
        <property type="entry name" value="TIGR00268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile and sulfur donor" evidence="1">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR006661-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="283" mass="29760" checksum="56A5639A519A5DCA" modified="2010-04-20" version="1">MAAQLDDNLTAALADLDARLRGHGSLLVAFSGGADSAFLLAAATRALGPDAVAAATAVSPSLPPSELDAAREFAASLGVRHLTPGTDELSREGYRANAGDRCYFCKSELLDTLNPLASQLGIATIATGTNADDAIAGFRPGIRAAAERGAITPLRDAGLTKSQIRTASRIWGLTTWDKPAAACLSSRIAYGIEVTSRGLSRVARAEAHLRTTLHNAGIPIRNLRVRDMGDDHAKIEVDPDLVEAVAASTLTTTLEDFTSVTLDPRGFRSGAMNELLPNPDKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q213</accession>
    <name>D3Q213_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Signal peptidase I</fullName>
            <ecNumber evidence="3 5">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2188</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the peptidase S26 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2188"/>
    <dbReference type="EnsemblBacteria" id="ADD41880">
        <property type="protein sequence ID" value="ADD41880"/>
        <property type="gene ID" value="Snas_2188"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2188"/>
    <dbReference type="eggNOG" id="COG0681">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028723_0_0_11"/>
    <dbReference type="OMA" id="RSQVWVK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="7">
        <location>
            <begin position="28"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="230" mass="25994" checksum="86292DE0FF71A15C" modified="2010-04-20" version="1">MPPGAVADDAEDNDKKPASKTKKKGSFWRELPVLLVVAVVVALLVRTFVLQSFWIPSGSMENTLQLNDYVLANKLIYDFRDPERGEIVVFKAPQSWQGAPGEEDFIKRVIAVGGDTVSYSKKDKHIRVNGEPLDEESYLYTNPETGKQQSPSLEDQEFKVKVPEGRLWVMGDHRWASGDSRERWERTEDEMESTIAVDSVIGKAFVLIWPVNRWDGLTIPDTFDGVPEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q216</accession>
    <name>D3Q216_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA protecting protein DprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017454.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2191"/>
    <dbReference type="EnsemblBacteria" id="ADD41883">
        <property type="protein sequence ID" value="ADD41883"/>
        <property type="gene ID" value="Snas_2191"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2191"/>
    <dbReference type="eggNOG" id="COG0758">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029601_2_1_11"/>
    <dbReference type="OMA" id="WPSQLDD"/>
    <dbReference type="OrthoDB" id="1881437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00732">
        <property type="entry name" value="dprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="384" mass="40369" checksum="FACCC1C8133F6BB6" modified="2010-04-20" version="1">MSVTDDRTALIALSVLCEPGNAALAELLAADGPASVLARLLAEPDASPLHQMVAARAQGRDVEGLVAGLVAAGDACGARIVTRYDAEWPEGVDDLAELFDEADPNTKPPLCLWLRGPRDLAEVAASSVSIVGARCCTPYGRNIATRLAYDLGRKQWTVVSGGAYGIDAAAHKGALSADGVTVAVLACGVDRPYPAANAGLFERIAETGLLVSEWPPGAIPQRYRFLVRNRVIAALTRGTVVVEAALRSGARHTARRALELERPLMIVPGPVTSEYSAGVHQLARGPGEVRVVTRAAEVIEDLGRIGADLAPPLCSPDAVRDTLDPLAARLVDAVPARRAASAEHIAAQAGVTVVEARRRLPELAMRGLVAYERDRYRLAGDADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q218</accession>
    <name>D3Q218_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0102 protein Snas_2193</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2193</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0102 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017456.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2193"/>
    <dbReference type="EnsemblBacteria" id="ADD41885">
        <property type="protein sequence ID" value="ADD41885"/>
        <property type="gene ID" value="Snas_2193"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2193"/>
    <dbReference type="eggNOG" id="COG0792">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1325672_0_0_11"/>
    <dbReference type="OrthoDB" id="2044249at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00048">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003509">
        <property type="entry name" value="UPF0102"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34039">
        <property type="entry name" value="PTHR34039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02021">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="149"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="100"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="207" mass="22928" checksum="69DEFCEC5F956952" modified="2010-04-20" version="1">MPHDRRHLRLGCFGENLAVAHLRRDGMRVLQRNWRCEHGELDIIAIERGVTVFCEVKTRRSLRFGTPMQAIDEAKALRIRRLAASWHRRYRDKPPWAEWLGLPPRRRAPNGGRRGGSPERGRHGNDPAGGGRGDGSPQRSRPSSRAEPAAGLGAGAGWLRGGVALVGTVVAVLAWRRGGRWRRRFDVVGVVLGGDGTATIDHRRGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2A5</accession>
    <name>D3Q2A5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4188</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4188"/>
    <dbReference type="EnsemblBacteria" id="ADD43838">
        <property type="protein sequence ID" value="ADD43838"/>
        <property type="gene ID" value="Snas_4188"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4188"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_3_1_11"/>
    <dbReference type="OMA" id="AGVWCGD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="216" mass="23122" checksum="97A8B25D8F8BCA8A" modified="2010-04-20" version="1">MLLGVTDLWTYVIATVLVILLPGPNSLYVLSVAARKGVRDGYRAAAAVFVGDSVLMIASAAGVASLLQTSPVLFTIVKYAGAIYLAYLGVMLIRSGIKTWRARRTDDADAPAETTNLERPFRRAFIASLLNPKAILFFVAFFVQFVDPAYPYPALSFLLLGAIVQVCSLTYLSVLIFSGNALASAFRRRRRLSSLGTGGIGAVMLGFAAKLSTASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2D6</accession>
    <name>D3Q2D6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019440.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4220"/>
    <dbReference type="EnsemblBacteria" id="ADD43869">
        <property type="protein sequence ID" value="ADD43869"/>
        <property type="gene ID" value="Snas_4220"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4220"/>
    <dbReference type="eggNOG" id="ENOG5033YX8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150093_0_0_11"/>
    <dbReference type="OMA" id="FEPSDWQ"/>
    <dbReference type="OrthoDB" id="1956224at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="15761" checksum="E4F13C29B77A8A72" modified="2010-04-20" version="1">MGTRGPVPKRSDQRRRRNLDAQVDTAPALAEPVAAPSLDFPAHPLAEDWYRSLSESGQAQYFEPSDWQAARLVAFDLTRHLNSGRASSQMLAALWSAMADLLSTEAARRRVRVEIERVADDGDQNVNGVVAVLDDYRRSIGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2G5</accession>
    <name>D3Q2G5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019469.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4249"/>
    <dbReference type="EnsemblBacteria" id="ADD43898">
        <property type="protein sequence ID" value="ADD43898"/>
        <property type="gene ID" value="Snas_4249"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4249"/>
    <dbReference type="HOGENOM" id="CLU_1884516_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="135" mass="14812" checksum="1620D5C96D1C7DE4" modified="2010-04-20" version="1">MTVTPIVPSLDAAAKRDHARFGQVFLLSGLACAQLDCTALAEDHPMAPAWDSKGQRVYQCAKECRRHSVLVETADDSAWFAFCAATNTAPHEITDRRQQRELLVANVTHVWLTCYPDADPVTAISWGSFPAVNPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2I2</accession>
    <name>D3Q2I2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4266"/>
    <dbReference type="EnsemblBacteria" id="ADD43915">
        <property type="protein sequence ID" value="ADD43915"/>
        <property type="gene ID" value="Snas_4266"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4266"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_18_7_11"/>
    <dbReference type="OMA" id="GHLGHVP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="160" mass="18016" checksum="5F93937D1B982EF1" modified="2010-04-20" version="1">MSDELNIRPATLADAEAIAEIWRQGWYEVHLETVPRELVEARTPESFDTRARKRVPDTVVATVHGEVAGFVMIHDDELDQVYVSAKHRGAGVAAAVITAAEDRVRSDGHRRAWLAVVADNPRARRFYERQGWVDDGDFDNPAWTPDGPVAVPTRRYVKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2T2</accession>
    <name>D3Q2T2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sugar isomerase (SIS)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021404.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6211"/>
    <dbReference type="EnsemblBacteria" id="ADD45833">
        <property type="protein sequence ID" value="ADD45833"/>
        <property type="gene ID" value="Snas_6211"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6211"/>
    <dbReference type="eggNOG" id="COG2222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012520_4_0_11"/>
    <dbReference type="OMA" id="YFIARAY"/>
    <dbReference type="OrthoDB" id="1046291at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="289" mass="30101" checksum="18B383B122D77A7E" modified="2010-04-20" version="1">MAIVDAEIARQPECWTAAAELAVEHAGLFPKAGERVAVVGCGTSWFMAQAVAGLREASGAGETDAFTASEFPDRRYDRLIALSRSGTTSEVVELLNRTDIPSLAIVGDGDTPAVAAADAAIAMPFASDQSVVMTSFATSVVALFRAQLGIDQAAAIADCRTALTAELPVDVAKLEQISFIGAGWTIGLANEAALKAREAATFWAESYPAMDYRHGPISIAGPNRATWELGPTGAGLRAEVEATGGAFVASSLDPLAELVLAQRLAVALARLRGLNPDSPRHLTRSVVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Z5</accession>
    <name>D3Q2Z5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ASCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015536.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0247"/>
    <dbReference type="EnsemblBacteria" id="ADD39965">
        <property type="protein sequence ID" value="ADD39965"/>
        <property type="gene ID" value="Snas_0247"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0247"/>
    <dbReference type="eggNOG" id="COG4405">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102450_2_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007374">
        <property type="entry name" value="ASCH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009326">
        <property type="entry name" value="DUF984"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39203">
        <property type="entry name" value="PTHR39203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04266">
        <property type="entry name" value="ASCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01022">
        <property type="entry name" value="ASCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ASCH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="110" mass="12300" checksum="87989792B1EA10F9" modified="2010-04-20" version="1">MYLNGRKTAGSSIKEDFLAAGDPLPRVGNFWIVLNSRAEPACLLRTEKIAVHKFYDVPPQIAVAEGEGDLSLEHWRRVHQAAYEPHLAEWGLASIADATVITEYYTLLFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q352</accession>
    <name>D3Q352_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycoside hydrolase clan GH-D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0304</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015593.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0304"/>
    <dbReference type="CAZy" id="GH36">
        <property type="family name" value="Glycoside Hydrolase Family 36"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40022">
        <property type="protein sequence ID" value="ADD40022"/>
        <property type="gene ID" value="Snas_0304"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0304"/>
    <dbReference type="eggNOG" id="COG3345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036399_1_0_11"/>
    <dbReference type="OMA" id="PAPTVWC"/>
    <dbReference type="OrthoDB" id="469334at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14791">
        <property type="entry name" value="GH36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002252">
        <property type="entry name" value="Glyco_hydro_36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="429" mass="47119" checksum="744F1B970AADFC07" modified="2010-04-20" version="1">MTFDEAARLRVDPGAGRVYEHGWQSWSPTREYPVAGTSYRQRTEYVHTGHLRPEKPVPTDGFQAEGLLVATDADGAAHRFATGSATDIPSIRARLDGDRLVVTADGTVEHTVHADVDTALTSFGDAFAARAGVSVRPAPTVWCSWYHYFTDVTEADIDENLDAIGEHELPVDVIQIDDGWQKAVGDWLDLSDRFTSLSRIVKRINDSGRRAGVWVAPFLALATSDLVRDHPEWIIDGAAGHNWGTETRGVDPRRARTYLTDVFTMLREAGFDYFKLDFLYAGAIDSVEAYREGLAEIRRVVGPESYVLGCGAPILPSVGLVDAMRVGPDIAVTYEPGNGDPCHPSQRGAAANTIARAWQHGRFWANDPDCLIARPEVERREEWADTVERYGGLVSVSDRIAALDEWGMDTTRRLLSNPPGPGPLAHGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q386</accession>
    <name>D3Q386_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015627.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0338"/>
    <dbReference type="EnsemblBacteria" id="ADD40056">
        <property type="protein sequence ID" value="ADD40056"/>
        <property type="gene ID" value="Snas_0338"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0338"/>
    <dbReference type="HOGENOM" id="CLU_1969196_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="127" mass="13365" checksum="E659C2A1FAE643EE" modified="2010-04-20" version="1">MGNAVLAGVALVMFGIFYWYKLWPKVQCWLLVAVGWGLGGMVGSGLQYALGQANDLSSTGMQLLFGVGVPGLFALATMTIFVLNMLPNKTVSTPPIGWVARICALLVPLTMVAMPSLGDNLMTSIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q388</accession>
    <name>D3Q388_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell division FtsK/SpoIIIE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015629.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0340"/>
    <dbReference type="EnsemblBacteria" id="ADD40058">
        <property type="protein sequence ID" value="ADD40058"/>
        <property type="gene ID" value="Snas_0340"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0340"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_389745_0_0_11"/>
    <dbReference type="OMA" id="IRRATWP"/>
    <dbReference type="OrthoDB" id="1127353at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="726" mass="77460" checksum="2C9E893A12112658" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q395</accession>
    <name>D3Q395_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015636.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0347"/>
    <dbReference type="EnsemblBacteria" id="ADD40065">
        <property type="protein sequence ID" value="ADD40065"/>
        <property type="gene ID" value="Snas_0347"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0347"/>
    <dbReference type="HOGENOM" id="CLU_1776309_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="146" mass="16134" checksum="9AD0159BD93827BB" modified="2010-04-20" version="1">MSHTHQQDIEYLRGLLNRAKHHVTVTVVHGLANARHRLNDQGHSDTEVARMLTAASPHSVGARHLRRTLDAIRDGRIHVGQYFNGAEADLGDIIASWATSSTGIDIADTMAALTTETVGFDEAVEQVDELLDECGRITDWLWKRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3B4</accession>
    <name>D3Q3B4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017526.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2266"/>
    <dbReference type="EnsemblBacteria" id="ADD41955">
        <property type="protein sequence ID" value="ADD41955"/>
        <property type="gene ID" value="Snas_2266"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2266"/>
    <dbReference type="eggNOG" id="COG1482">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_466831_0_0_11"/>
    <dbReference type="OMA" id="FIETRRH"/>
    <dbReference type="OrthoDB" id="645703at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="609" mass="67866" checksum="3EFB44996D197211" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3M1</accession>
    <name>D3Q3M1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-isopropylmalate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.85</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4289</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.85" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019509.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4289"/>
    <dbReference type="EnsemblBacteria" id="ADD43938">
        <property type="protein sequence ID" value="ADD43938"/>
        <property type="gene ID" value="Snas_4289"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4289"/>
    <dbReference type="eggNOG" id="COG0473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031953_0_1_11"/>
    <dbReference type="OMA" id="EYDLGAR"/>
    <dbReference type="OrthoDB" id="1551125at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003862">
        <property type="term" value="F:3-isopropylmalate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="2">
        <location>
            <begin position="3"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="346" mass="36492" checksum="563173441D3C1986" modified="2010-04-20" version="1">MTRIAVIGGDGIGQEVTAEARKVLAVALPNLEANEYDLGASRYHATGEVLPESVQAELDQHDAILLGAVGDPTVPPGVLERGLLLKLRFDFDQYVNLRPSKLLPGAETPLADVKAGEIDLVVVREGTEGLYAGAGGVLHKGTSAEIATEESLNTRYGTERVVRDAFERAKRRDRKHVTCVHKTNVLSYAGGLWRRTFDEVATEYPDVTTDYQHIDAAAMFMVNRPQHFDVVVTDNLFGDILTDIAAAVTGGIGLAASGNVNPDHAHPSMFEPVHGSAPDIAGQGIADPIAAILSTSLLLDHIGQGEAATAVSQAVTAELSGRTPGEPLSTAAVGDRVAARVAEILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Q6</accession>
    <name>D3Q3Q6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid permease-associated region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4326</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019544.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4326"/>
    <dbReference type="EnsemblBacteria" id="ADD43973">
        <property type="protein sequence ID" value="ADD43973"/>
        <property type="gene ID" value="Snas_4326"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4326"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_18_1_11"/>
    <dbReference type="OMA" id="WEAASHL"/>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="385"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="428" mass="43269" checksum="D1507326EA62BFAC" modified="2010-04-20" version="1">MTDQLTKGDSHTSYARPSLGMGRGTAMYIGAILGPGILALPGLAAAEAGPASIVTWIVLLGLSVPVALSFAALAAKFPDAGGVATFVRRAFGARPAGIVGWWFYCVIPIGAWTAGIIGAEYVGEALGLGGTGKLLIGLGLLAAAFGANHLGLRLSGGTQLLLMIVLVLLLGVATVAGALHVSAANLTPFAPHGVAGIVSAAGVLFYAFAGWEAASHLSGEFTDPARQLRRVTGYTLLIVSVLYIGLSIVTVGALGGDAATSPVALTALLTYALGPAAAPVTAIIALVLSFGALNTFVAGASRLGAALARDGDLPAVLARGGRPGEIPHRSLLLLGSLTAVATTVSITFSFNLDDLMRATSACLAAVTVLGCAAAVRLLRGRSARAMAIAATGFTTVVLASMAWYLLVPLGIAALALGYRWTRRERPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q473</accession>
    <name>D3Q473_STANL</name>
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        <submittedName>
            <fullName evidence="5">Bilirubin oxidase</fullName>
            <ecNumber evidence="5">1.3.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6341</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.3.5" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021529.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6341"/>
    <dbReference type="EnsemblBacteria" id="ADD45958">
        <property type="protein sequence ID" value="ADD45958"/>
        <property type="gene ID" value="Snas_6341"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6341"/>
    <dbReference type="eggNOG" id="COG2132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_366772_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047705">
        <property type="term" value="F:bilirubin oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
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        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="4">
        <location>
            <begin position="535"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="725"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="760" mass="85868" checksum="F83349A949DCB29D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q476</accession>
    <name>D3Q476_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6344"/>
    <dbReference type="EnsemblBacteria" id="ADD45961">
        <property type="protein sequence ID" value="ADD45961"/>
        <property type="gene ID" value="Snas_6344"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6344"/>
    <dbReference type="eggNOG" id="COG5486">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065506_1_0_11"/>
    <dbReference type="OMA" id="YQWTPLK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018688">
        <property type="entry name" value="DUF2182_TM_metal-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09948">
        <property type="entry name" value="DUF2182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="268" mass="28804" checksum="0B54A476C306A88F" modified="2010-04-20" version="1">MTATAEKSVRAPKWTWRDVPLPLGMSLVATAGLVLWHFSPWTHYMHLTLPSGGHDHHGGGAEPGMTAMVGLFTGAWLLMTVAHMLPTAIPLLASFRRVAARRPERTRLTVVVVAGFLTVWAAAGAAISFAHVHLRYLVEMNSLQAAAPWFLVATLVAAGAYQFSNYIAKCVTACRSPFSFIGKHWKGGDSVAGQSFRIGLDYGQSCLGCCAALMVVMFIVGSASHLWMVVFALFGVIQKSARWGGRLTRPMGVGFFVAAGVVAALQFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4F0</accession>
    <name>D3Q4F0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator, PucR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015681.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0393"/>
    <dbReference type="EnsemblBacteria" id="ADD40110">
        <property type="protein sequence ID" value="ADD40110"/>
        <property type="gene ID" value="Snas_0393"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0393"/>
    <dbReference type="eggNOG" id="COG2508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053843_0_0_11"/>
    <dbReference type="OMA" id="GSRELWC"/>
    <dbReference type="OrthoDB" id="1439158at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_30" evidence="1">
        <location>
            <begin position="349"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="418" mass="45513" checksum="1DE39595ACC69A23" modified="2010-04-20" version="1">MSDGHGVGNRVLMLGGQPLHQMLRLRAPELARQLTEIIAAHVTTYNNLPDEELQRDIVSLVELNLNLVANTFEHHSPPKPEEMELLWAAAGRGAQDLTPLEDIMTAYHLGGRQATVALFADAAPEDYGDIVEAYSLLLKYNQVVSTVVCEGYMVARESMRSQEQDARHAVVSALLNGERPMNAGALAGVRLASRYLVFTAAIGKHPDEADDKPFAVYAGRSKLDRIRTVLDGFASEPALTVLDPAGGLILAPASDSMMDWKGARELVAVVGQAAGAPVWIAGQLATIEEVPAAARLTQEVLDVVRLFGRPPGLYQLSDVLLEYQLTRPSHAMEELASLLDPLAEHPDLQRTLEVYVENGLDRRQAAALLHVHPNTVDYRLRRVVALTGLDPVDPVQLQRIGAALAARRKRVAKPDTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4F4</accession>
    <name>D3Q4F4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0397</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EccE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015685.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0397"/>
    <dbReference type="EnsemblBacteria" id="ADD40114">
        <property type="protein sequence ID" value="ADD40114"/>
        <property type="gene ID" value="Snas_0397"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0397"/>
    <dbReference type="HOGENOM" id="CLU_043760_0_0_11"/>
    <dbReference type="OrthoDB" id="832050at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021368">
        <property type="entry name" value="T7SS_EccE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11203">
        <property type="entry name" value="EccE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="365" mass="38986" checksum="981BA32FCF90733C" modified="2010-04-20" version="1">MTSPAKPATDAGAKPEPVTAARRTRTRVAGLGIAQVIGVEVVLAALLFVPGVPLPWLGGVAAAVALLGLGRTHGRSWFGWLGHWLRWRSRVRADRRDRRSGGEPGPRPRLATIAERGTEIGVAFDGTGWFAAVKLEGEAPPSEVFAAVTGLLNAADTPVTSVQLVTRSGAEVGRDNWFAVRLDVPGAHAVAADRGGGALGVHRALGGAVSRLLKGAQDAGIDMRALSQTQLAAALRFSLDLHRPDSGEPTESWKTWRNGGMAQTTYWLRGRRSAATEVERLWTKLSELDKGTHAISLALRPASSRPGDKRLMFRCLVRLVDEASNVEELGRELTKLTRKNRLKLLRCNGTQGPASYASALSGGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4J1</accession>
    <name>D3Q4J1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Adenosinetriphosphatase</fullName>
            <ecNumber evidence="5">3.6.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0436</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.3" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015722.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0436"/>
    <dbReference type="EnsemblBacteria" id="ADD40151">
        <property type="protein sequence ID" value="ADD40151"/>
        <property type="gene ID" value="Snas_0436"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0436"/>
    <dbReference type="eggNOG" id="COG0464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_12_3_11"/>
    <dbReference type="OMA" id="RAPDLCD"/>
    <dbReference type="OrthoDB" id="1115436at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003338">
        <property type="entry name" value="CDC4_N-term_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02359">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01073">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDC48_N" evidence="4">
        <location>
            <begin position="5"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="269"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="520"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="749" mass="79266" checksum="98E7C464AA5BF85A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4J7</accession>
    <name>D3Q4J7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015728.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0442"/>
    <dbReference type="EnsemblBacteria" id="ADD40157">
        <property type="protein sequence ID" value="ADD40157"/>
        <property type="gene ID" value="Snas_0442"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0442"/>
    <dbReference type="HOGENOM" id="CLU_1069228_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="27304" checksum="DA3AE0A4312EB16E" modified="2010-04-20" version="1">MSNPPQGLGEPVNGAPDMRAPAGPAPRPLYPQYPTTAPPLAPPPLDDEPRDKTKWALLVGLAGVAIIGLVTALFVIPDGPSGGPSPDAAASSDVAIECEPGPAPEGEPLTAERFYEDKVWTNSIDDNVTADRTGRWNHEGCCDVGLGSAQQELNDLGCAYGIEAAYESADGHLGIAQLILAFGDTGAAMAASDMEFTSFRLHEESGVYDDSMEVYGYVEPSGDFLVLTIGSIDSDDSTIVNEAQSTLEAFHVDYASTLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4K1</accession>
    <name>D3Q4K1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015732.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0446"/>
    <dbReference type="EnsemblBacteria" id="ADD40161">
        <property type="protein sequence ID" value="ADD40161"/>
        <property type="gene ID" value="Snas_0446"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0446"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_686782_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="75"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="401" mass="44138" checksum="2AF086EA96AE2816" modified="2010-04-20" version="1">MTSGLDTADITSRVNRYVDVGRHAEAERIVRRALHTDPGNISLLNDLSYTLYKQKRHDEMLEVCRTALAIEPDSPDMLQRLGLALEALGRRAEAIEATSRGLEQAPDHHYLMRDHAHLLLLDGLNHEAVAGFRRALEVYPDDAVLMGLLGDALLQVDEFREAHELLTASLADRPESADALLSLGTAQMFLFHVRASLKTLALTVRADPDDARRCAVVRYLMAWPISHIYSALRWSLPAAALAALTASLLGTTDWLQWTITGFTFAAFAYSAHWFARGGLPAWRALFRLPPGEIALTATGIGLGYGGCVAVLAATWLSSPLLAGIGLAATALMWIVEAVEWSLDPDEDQTVPLHRRTLANLRPIVKDDLTVLKQLRARRELRRARATAATEPSRQASSQPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q503</accession>
    <name>D3Q503_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Band 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2501</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2501"/>
    <dbReference type="EnsemblBacteria" id="ADD42183">
        <property type="protein sequence ID" value="ADD42183"/>
        <property type="gene ID" value="Snas_2501"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2501"/>
    <dbReference type="eggNOG" id="COG0330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024949_2_1_11"/>
    <dbReference type="OMA" id="NTFWVIP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018080">
        <property type="entry name" value="Band_7/stomatin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01270">
        <property type="entry name" value="BAND_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="4">
        <location>
            <begin position="25"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="322"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="406" mass="43567" checksum="237788FAB04A8B0E" modified="2010-04-20" version="1">MSGGEVFLVLLLGLVALFFIIMLFKMVRIVPQQQEYIVERLGKYSKTLTPGLNFLVPILDAVRSKVDKREQVVSFPPQPVITSDNLVVSIDTVIYYMVTDSVRATYAISNYLQGVEQLTVTTLRNVVGSMDLEQALTSRDTINSALRTVLDEATGQWGIKVTRVEIKAIDPPPSVRESMEKQMRAERDKRAAILTAEGVKASQVLTAQGEQEAAVLRAQGDRQARILQAEGQSKAIETVFTAIHKSNPDEKLLAYQYLQTLPQIAAGQSNKLWMIPAELTRALESFSGAVGGPISSGPASAVTNAVSQALSSEQDGTGEAAPSHTDADRSETAPRTPSAEDDDAATTRIGKPKPGTDDTQALEAGPKVSPSQFTATDAANTMLDSTQVVPPPVPPTKPGDLPPTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q506</accession>
    <name>D3Q506_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2504"/>
    <dbReference type="EnsemblBacteria" id="ADD42186">
        <property type="protein sequence ID" value="ADD42186"/>
        <property type="gene ID" value="Snas_2504"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2504"/>
    <dbReference type="eggNOG" id="ENOG5032EMY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1174907_0_0_11"/>
    <dbReference type="OMA" id="VISAWRP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="211" mass="22433" checksum="C4427F67F40D3A15" modified="2010-04-20" version="1">MTPTPLARLSLLLSPPLVMLGWALMRLLGTDGREPGWTLAHLAWLAGYVLLAVACVYLYRLTVTGGAPGRRSLAASFLAVALFGSLCMNTQMAIDLVAGFATSTVEAKNAFTDDIQALPGVELLVYQLGPALLFCALSAQTIHAYLARRLPVSVPVLVGLAVLVMVVDRLVDTPFRLTMGVASVLLWIAFTTVVKTRPATSASPVDVQRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q593</accession>
    <name>D3Q593_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019713.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4497"/>
    <dbReference type="EnsemblBacteria" id="ADD44142">
        <property type="protein sequence ID" value="ADD44142"/>
        <property type="gene ID" value="Snas_4497"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4497"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075874_0_0_11"/>
    <dbReference type="OMA" id="PRRERMW"/>
    <dbReference type="OrthoDB" id="1681721at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045383">
        <property type="entry name" value="DUF6528"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20138">
        <property type="entry name" value="DUF6528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048670" evidence="1">
        <location>
            <begin position="30"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="320" mass="34939" checksum="47EE070ED3E874BD" modified="2010-04-20" version="1">MRRRTLFTGLAAVGAAGTAAAVFGRSALADSEAAAAKANYQVAITEQVSNKVMIFARNSKWDNAHMLRSFRPGGGGGWSNLSDVKFRETHKYNNIGLFTCSGGNVGVWNLKSERHQEFNDVLWWATPGGNPHAIERIPHNGSVVTASSKGYISVYGPKSAVMSSLGKKAVQTFGLPGAHGVLWDEVSNLLWAVGDKTVRSYKVTGSGRGTRLREAGARIKLPGLGHDLQADHSNKGRLLVTDTKGVYEITKSNRGIREIRQADHVKSFCRHSSGEAFWTIPNWPKPSNWRTNTVGFDGGYSRKRGGAGIYKARLFYPKYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5F2</accession>
    <name>D3Q5F2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021583.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6396"/>
    <dbReference type="EnsemblBacteria" id="ADD46012">
        <property type="protein sequence ID" value="ADD46012"/>
        <property type="gene ID" value="Snas_6396"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6396"/>
    <dbReference type="eggNOG" id="ENOG5032SFN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113711_1_0_11"/>
    <dbReference type="OMA" id="EHEPNRG"/>
    <dbReference type="OrthoDB" id="1793636at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014487">
        <property type="entry name" value="DUF3151"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11349">
        <property type="entry name" value="DUF3151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017349">
        <property type="entry name" value="UCP017349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD46012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="135" mass="14780" checksum="D26951809EDF840E" modified="2010-04-20" version="1">MPNSNLLPEPPATLLPEDDEQLAVQTEHGPAEAARRYPTFCYAWAKLAAAAREQGEDLAAYAYARTGYHRGLDQLRRNGWKGHGPVPWSHKPNRGFLKALYQLSLAADAIGEADEAARCAQFLRDCDPSAADAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5F5</accession>
    <name>D3Q5F5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6399</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021586.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6399"/>
    <dbReference type="EnsemblBacteria" id="ADD46015">
        <property type="protein sequence ID" value="ADD46015"/>
        <property type="gene ID" value="Snas_6399"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6399"/>
    <dbReference type="eggNOG" id="ENOG503303Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152487_1_0_11"/>
    <dbReference type="OMA" id="TWGEMRT"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD46015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="108" mass="12355" checksum="BC6D1E58DEC64010" modified="2010-04-20" version="1">MRAADLSHPTVRGVVNALRHGDRDAFYAAFADDVRLTSEGRDRDLYCWAESEIFPEHGRIAVRAERHDGRVVIGSYHSDRRNLPNTAWRFDIVDGLIRYLDVGEARES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5M9</accession>
    <name>D3Q5M9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cell cycle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_6474</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6474"/>
    <dbReference type="EnsemblBacteria" id="ADD46089">
        <property type="protein sequence ID" value="ADD46089"/>
        <property type="gene ID" value="Snas_6474"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6474"/>
    <dbReference type="eggNOG" id="COG0772">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029243_3_1_11"/>
    <dbReference type="OMA" id="IFCTVGE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="459"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="464"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="481"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="514"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD46089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="529" mass="56672" checksum="774B5C8640F1DD65" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5T3</accession>
    <name>D3Q5T3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015803.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0517"/>
    <dbReference type="EnsemblBacteria" id="ADD40232">
        <property type="protein sequence ID" value="ADD40232"/>
        <property type="gene ID" value="Snas_0517"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0517"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_979724_0_0_11"/>
    <dbReference type="OrthoDB" id="1885106at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="139"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="284" mass="31655" checksum="C53560FCDBE5DD0C" modified="2010-04-20" version="1">MQIEKFVDQFELLAEAHGITTAALLQRLERQDDDRPRWIAVENGRGIGVASASMTPDRKVRLWLDCRDSIAYQPLVRAASAAFRTDVYTSVSGSDLLLRRAFTAEGFRLDYTEDVFAARFTTAAVALRKARLPDGFSLITADQADGRSWFTLDNTLRQDIRGNEGWRGDLKWFAEHTHGASNFDPAAHIIAVDDTNGEYAGLVRFWNRPGASPRLGMLAVLRQYRGCGLGSALLARGVEVASTWDHERFTGETAREATEMRALWIAMGGTETDSRQTLVLRRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q686</accession>
    <name>D3Q686_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF418 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017832.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2581"/>
    <dbReference type="EnsemblBacteria" id="ADD42261">
        <property type="protein sequence ID" value="ADD42261"/>
        <property type="gene ID" value="Snas_2581"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2581"/>
    <dbReference type="eggNOG" id="COG2311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039610_1_0_11"/>
    <dbReference type="OMA" id="FWSFETA"/>
    <dbReference type="OrthoDB" id="1742337at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04235">
        <property type="entry name" value="DUF418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="DUF418" evidence="2">
        <location>
            <begin position="221"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="388" mass="41309" checksum="7FEC4251FEC5D4B1" modified="2010-04-20" version="1">MSTSTVQPVGPVADTERSLAPDLGRGLMLALIALANSAVYLYNRPYGARQHIIETEFLDRLVAFVNTVFVEVRAYPLFAALFGYGVVHAYRRGRAASDDHRARGILRRRGFWLIVFGAVHALVLFSGDILGLYGVLSLILLTMLRLRDRTLLIVGGAWLVLAAVVQGLVYSDSGPNEERAFFWSFTTTEPLAAAGLRVGEWLMTPFGLVGVFSAALAGMWAARHGVLDQPGRHRTLLKRVAAIGVGLSVLGGIPIGTQVAGVWSSTSFGTDYAVSAVHVVTGVAGGLGYAALFGLLAARIGNRPGPVLRAVAACGQRSLSFYLFQSVIFVALFVPYTLGLGGELGSAATAGVALATWLAGVGLAELLRRAGRRGPAETLLRRLSYRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6K9</accession>
    <name>D3Q6K9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arylamine N-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4609</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the arylamine N-acetyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.5" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019823.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4609"/>
    <dbReference type="EnsemblBacteria" id="ADD44252">
        <property type="protein sequence ID" value="ADD44252"/>
        <property type="gene ID" value="Snas_4609"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4609"/>
    <dbReference type="eggNOG" id="COG2162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049918_1_1_11"/>
    <dbReference type="OMA" id="CYEHNTL"/>
    <dbReference type="OrthoDB" id="1687886at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004060">
        <property type="term" value="F:arylamine N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001447">
        <property type="entry name" value="Arylamine_N-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11786">
        <property type="entry name" value="PTHR11786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00797">
        <property type="entry name" value="Acetyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01543">
        <property type="entry name" value="ANATRNSFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="290" mass="31709" checksum="9D660F3E61FB787C" modified="2010-04-20" version="1">MSSRPAHLTPSREYFTGWGASQFDLDAYTKRVGFDGPLRPDLDTLVGLHRAQPTHISFENLDIVLGRGIDISLEALQRKLIHQRRGGYCYEANLLFAAALEAAGFTVTGALARSRIDSDALRPATHAILLVWLDDDAPWLADAGFGGRGLLEPIRVTDGNESTQGSWRFRLDQVDETEWILSTTDADGWKDLYGFTQVPRYPFDFAVANHFTSTHARSPFTGRLVAQRVGEHTRILLVDTELTVLHGSAKSETTTIAAADIPAVLTERLGISLTDAEYAAVVTAVAAKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Y6</accession>
    <name>D3Q6Y6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0672"/>
    <dbReference type="EnsemblBacteria" id="ADD40385">
        <property type="protein sequence ID" value="ADD40385"/>
        <property type="gene ID" value="Snas_0672"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0672"/>
    <dbReference type="HOGENOM" id="CLU_833966_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="333" mass="34201" checksum="9B2A1FD5AAB339E5" modified="2010-04-20" version="1">MGNYSEMSYEQLVAYVMSGDPTALTQAARDWKQATQSADEVHGILRPKAQVVKPSYRGTDGSAYGERLDTLGGFAKQLNVDAQDAYEGMLNAATALQQAQRQAEPIIAMVEAASGKEKEKLKKLAAKLLAAIMEQLAAAYQDTVDKKWHDPAPGPEGTGDQAEDRSRLPWDTAPHGQDPTGVQPLPYPTGPGYGSGAYQPYDPQDGLHGGGGLAGGATSAPTLPTGPAASAPVAAATTAGAIGASPSVPPVMGGLAAAGGGAAAPSPAPRAAGRAPGSAAGKSGPIGAGLMPPYSPHGEDDDERGEHTWLTEDEIPWTRENSAPVVIGKQEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q735</accession>
    <name>D3Q735_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0722</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016005.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0722"/>
    <dbReference type="EnsemblBacteria" id="ADD40434">
        <property type="protein sequence ID" value="ADD40434"/>
        <property type="gene ID" value="Snas_0722"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0722"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_3_11"/>
    <dbReference type="OMA" id="FDTGWRG"/>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="119"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="340" mass="36366" checksum="B39FE9CB40BF3C15" modified="2010-04-20" version="1">MKDMLILLGIAVICAVAVAVPGALVLRRLRGRSVTVMVSALLVITVLALLAAIVGASVEMFLNTHDLNVVLILVGVSGTVGLAIAVWLGRRMTAEAMWQEELRARERQLEARRRELVAWVSHDLRTPLAGLRALTEALDDGVVRDEAGVAEYHRRIRDETMRMSRLVDDLFELSRINAGAVRPQLRPVSLPEVTAEAMAAVQPLSHRYGVQLRHEEPGGVIVTGSHPELLRIMENLLRNAIRFTPSGGTVTVYSGAAAGYGLVSVADSCGGIPADDLPRVFDVAFRGEAARTPDGDPRRGDTGAGLGLAIVHGLVSAHNGRIAVSNVAGGCRFDVRLPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q772</accession>
    <name>D3Q772_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2666</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017914.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2666"/>
    <dbReference type="EnsemblBacteria" id="ADD42343">
        <property type="protein sequence ID" value="ADD42343"/>
        <property type="gene ID" value="Snas_2666"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2666"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="VNTAFMM"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="15"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="487" mass="50626" checksum="7622DEF5FFA21F4A" modified="2010-04-20" version="1">MSPEKLSELRRRWLAVIVLCAAQVMIILDQNIVNVALPAIREDLDFSASNLVWTINAYVIPFGGLLLLAGRLGDLLSRKYVFVAGLALFTAASAWCGFADGQTSLLVARFVQGLGGAVTSAGLLGMVVTIFSDPKPQAKALGAFGFASAGGGAAGTVVGGVLTEGLSWHWVFWINIPLGIIVGALALRLLRNDRGIGWRAGADVFGAVLVTSGLMLVVYALVGTESRGWASPVTIGLGAAAVALLAGFFVRQAKAANPLLPLRILRSRNVAGANLIQALMVAALFGFMFYTVLYMQEVLSYRPLSAGLAFLPVPIVIAVVSMTVAPKLLLRFGPRTLILAGLPLLAFGLWLLSRVPVDGDYYLHLLPAMVIMPFGFGITMPSLMSLAMSEVAAEDSGVTSGLFNTTQQVGGAIGLAVVSTAVAARIDSTLADGGDKAQALTDGYGLGFGLGAAFVAVAWLVALTVLRQRAKPEAAGSDEPAVAAAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7I6</accession>
    <name>D3Q7I6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019899.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4685"/>
    <dbReference type="EnsemblBacteria" id="ADD44328">
        <property type="protein sequence ID" value="ADD44328"/>
        <property type="gene ID" value="Snas_4685"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4685"/>
    <dbReference type="eggNOG" id="ENOG5032YPP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_185993_1_0_11"/>
    <dbReference type="OMA" id="WAHIGQA"/>
    <dbReference type="OrthoDB" id="1850835at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="78" mass="8515" checksum="0AE4007FD80CEB5C" modified="2010-04-20" version="1">MSDTEIPVPTDPSDALAAVAALRKLADGLEDAAVEQAMRSGWSWPQVAEALGVTRQAVYKKHSRRLIDAGVKLRRRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7P7</accession>
    <name>D3Q7P7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF305 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4747</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019960.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4747"/>
    <dbReference type="EnsemblBacteria" id="ADD44389">
        <property type="protein sequence ID" value="ADD44389"/>
        <property type="gene ID" value="Snas_4747"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4747"/>
    <dbReference type="eggNOG" id="COG3544">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074343_0_0_11"/>
    <dbReference type="OMA" id="MTWMGMG"/>
    <dbReference type="OrthoDB" id="1714516at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005183">
        <property type="entry name" value="DUF305"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03713">
        <property type="entry name" value="DUF305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048930" description="DUF305 domain-containing protein" evidence="2">
        <location>
            <begin position="33"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="DUF305" evidence="3">
        <location>
            <begin position="38"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="199" mass="22003" checksum="4E5C33F533D3F6F2" modified="2010-04-20" version="1">MRRYLKAAAVLAAVALVATTAWLFVVPEPTPAEDSPEAGFARDMNVHHGQAVAMSMYVYRNGSDSRMRDLAYDIALTQQAQIGMMSGWLDEWGLPPTSTEPPMSWMDHNMPIPDDGLMPGMATQDQLGELYAAKGSEADAIYSELMITHHEYGIHMAKAIRDRTDLPRVDDLAESMVKGQRSEIKALEQYGDRDVADEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7S7</accession>
    <name>D3Q7S7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4778</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019990.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4778"/>
    <dbReference type="EnsemblBacteria" id="ADD44419">
        <property type="protein sequence ID" value="ADD44419"/>
        <property type="gene ID" value="Snas_4778"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4778"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_42_1_11"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="202" mass="22227" checksum="27742E1B3CF6085F" modified="2010-04-20" version="1">MPVAFSDGERDHITAELKAAGRRLFTTVGLRKTALADLVVSAGIVKSTFYSFFDSKEALYLELLLDQFGNTRRLTVEEGLNAGTDTLDALRRYLRGAVTVLDTDPLYRRLVTHPEEMAMVQRKLGPDAFEQAGDSGLSDLMAFVTDRQTRGELPKGDPTIVVGALRAVLLLPLHAHEFGEDYPKVLNMTIDALTAGLVHDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7X7</accession>
    <name>D3Q7X7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016053.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0770"/>
    <dbReference type="EnsemblBacteria" id="ADD40482">
        <property type="protein sequence ID" value="ADD40482"/>
        <property type="gene ID" value="Snas_0770"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0770"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083309_0_0_11"/>
    <dbReference type="OMA" id="VDRHWNL"/>
    <dbReference type="OrthoDB" id="705269at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041413">
        <property type="entry name" value="MLTR_LBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17765">
        <property type="entry name" value="MLTR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="17"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="262" mass="28517" checksum="15F66EDC916D4BE0" modified="2010-04-20" version="1">MTQLAEPATTPPAGELIRHWRGQRHLTQQQLSIRCGVSTRHLSFIETGRSRPTASMILRVCEELDVPLRHRNDILLAAGHAPAFTESSLEQPSMRSISQALIQILDGHLPFPAVVVDRHWNMVDANAAIDPLTEGCDAALLEPPVNVLRLSLHPDGMAPRIRNLPQWRGHILSRLDHQIRTTGDAELERLRTELGGYPGGVDHAPGHSLVVPLRVTTAAGVLSFFSTTTVFGTPMDVTVAELAIESFFPADAETAAALRGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q816</accession>
    <name>D3Q816_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016092.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0809"/>
    <dbReference type="EnsemblBacteria" id="ADD40521">
        <property type="protein sequence ID" value="ADD40521"/>
        <property type="gene ID" value="Snas_0809"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0809"/>
    <dbReference type="eggNOG" id="COG0657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_5_1_11"/>
    <dbReference type="OMA" id="MYPVISM"/>
    <dbReference type="OrthoDB" id="1470522at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0858">Xylan degradation</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="1">
        <location>
            <begin position="59"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="262" mass="27899" checksum="93FCE3C507D98530" modified="2010-04-20" version="1">MAVAISASQPTISERITVYPADDRFTGPRPSVLVLPGGRYRELPPHEGEGYARWLSSIGLHAFVLAYRLLPEQFPAPLEDARAALGHIRGGEHGLDVGSVGVIGSSAGGHLAGLLMTGTVLSTEDGVVEPPRPDFAILAYALADFDLLPPVAVEGLLGDLMFLKDELSPAKHVDSTVCPTFVWATSEDPPGLPNALEWTRVLAEAGVPVELHVLPRGGHGIGLADGVEYGGQGHVFIKRDAHTATWTDSCERWLRHEGVLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q838</accession>
    <name>D3Q838_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="6">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tilS</name>
        <name evidence="9" type="ordered locus">Snas_0831</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0831"/>
    <dbReference type="EnsemblBacteria" id="ADD40543">
        <property type="protein sequence ID" value="ADD40543"/>
        <property type="gene ID" value="Snas_0831"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0831"/>
    <dbReference type="eggNOG" id="COG0037">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018869_1_0_11"/>
    <dbReference type="OMA" id="PWQDPHN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015262">
        <property type="entry name" value="tRNA_Ile_lys_synt_subst-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09179">
        <property type="entry name" value="TilS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ATP_bind_3" evidence="7">
        <location>
            <begin position="39"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="TilS" evidence="8">
        <location>
            <begin position="270"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="44"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="344" mass="36657" checksum="F7EF870426118610" modified="2010-04-20" version="1">MTGPPAAVARVRVAVRRLLTELSPSGNADESPSSGDRLVLVACSGGPDSMALAAATAFVAPRLGIRAGLVTVDHGLQAGSAKRAATVADWARDAGFEPVEVATVEVDVTAGGPEGAARDARYAALTEAAQRLGASAVLLGHTRDDQAETVLLALARGSGPRGLAAMPRKRRKFRRPLLDLPRADTVRACRDLELPVWDDPHNTDPAYARSRLRAVMPVLAETFGERFVANLARTATLVAADNDALDAYAAEVLAKASHGTLSAELLEPNLKLGPLNAARRAVRTRALRAWVLSEGAEADALSYVHIEAMEALVMNWRGQGPVFLPGNVTVWRERNRLRLRRTEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q850</accession>
    <name>D3Q850_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase III, delta prime subunit</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016126.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0843"/>
    <dbReference type="EnsemblBacteria" id="ADD40555">
        <property type="protein sequence ID" value="ADD40555"/>
        <property type="gene ID" value="Snas_0843"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0843"/>
    <dbReference type="eggNOG" id="COG0470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006229_4_1_11"/>
    <dbReference type="OMA" id="GFCDGCH"/>
    <dbReference type="OrthoDB" id="1971388at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="33"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="389" mass="41197" checksum="60B7A7B88CEBB0C7" modified="2010-04-20" version="1">MTGEIFDRLIGQEDTVQTLTDAVAAATSGAAGMTHAWLFTGPPGSGRSVAARAFAAALQCPNQGCGSCPACHTVLGGTHADVTHVIPDGVTIGVSVMRDLIGTAQRAPGTGRWRVLVIEDADRLTEAAGNALLKSIEEPPERTVFLLCAPSSNPAEISVTIRSRCRLVPLRQPSVAAVARLLETRDGVDPSLARLCASAAQGHVGRAKRLATDPQARDRRDTVLGVPRQLSSVGACFTAADAIIEASESEATDATKGQAEREIAELETALGKGGTGKGASKATRGNAGQIKELERRQKMRLTRAQRDTLDRALVDLAAFYRDVLIQGLGARVDPIHPDAAEAVTAAASRWSPESVIRRIDAILQCRIAIDRNVRPRIAVESMMLKLWQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q866</accession>
    <name>D3Q866_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2764</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018011.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2764"/>
    <dbReference type="EnsemblBacteria" id="ADD42440">
        <property type="protein sequence ID" value="ADD42440"/>
        <property type="gene ID" value="Snas_2764"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2764"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_2_2_11"/>
    <dbReference type="OMA" id="RREWPRH"/>
    <dbReference type="OrthoDB" id="1425840at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="25"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="159"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="31890" checksum="0B4EF071BA42ECF2" modified="2010-04-20" version="1">MTQAPSRPASRGGVRSSGVAGVTMLTATVPAVWGTTYLVTTEFLPPGHPLVSSVIRALPAGLVLLALTRTLPHGKWWWRSLLLGTLNIGALFALLFVAAYRLPGGVAATLTAIQPLFAVGLAFALLGEKPTRWRFGWGLVGVAGVGLIVLRGQLSFDLLGVAAGIGAAAALAAGIVVTKHWGRPEGVGPTTIAAWQLTAGGLVLLPLALAVEGLPAEVDLRAVGGYAWLAIVGALLTYPIWFHGIGRLPVVAVSFLPLLSPVVAALLGWLVLGESLTPWQGVGFALALAAIAAAQLNPDLLRSPTTSKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8I4</accession>
    <name>D3Q8I4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018129.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2883"/>
    <dbReference type="EnsemblBacteria" id="ADD42558">
        <property type="protein sequence ID" value="ADD42558"/>
        <property type="gene ID" value="Snas_2883"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2883"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_2_2_11"/>
    <dbReference type="OMA" id="AMTVYRH"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041347">
        <property type="entry name" value="MftR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17754">
        <property type="entry name" value="TetR_C_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="195" mass="21659" checksum="719177BB0A6E6321" modified="2010-04-20" version="1">MPDIRDRRRRETRRALQEHALRLFTERGYDSTTVNDVAEAAGVSAMTVYRHFPSKEDLVLLASYDELIAERVAAQPPDQPDARRIGRAIVDTATAGVASDADRRSLLALLRLMIDTPAIRARHLDSQYATQTAIVEAMRTEATDPETEFRRWVTAGACLAAMHAAVVRWADEDGRPELPGLIETALSATFANEFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8W7</accession>
    <name>D3Q8W7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0865</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0719 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0865"/>
    <dbReference type="EnsemblBacteria" id="ADD40576">
        <property type="protein sequence ID" value="ADD40576"/>
        <property type="gene ID" value="Snas_0865"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0865"/>
    <dbReference type="eggNOG" id="COG3766">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135044_0_0_11"/>
    <dbReference type="OMA" id="WVERNRN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007140">
        <property type="entry name" value="DUF350"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03994">
        <property type="entry name" value="DUF350"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="141" mass="14814" checksum="3DF36CA52802E25C" modified="2010-04-20" version="1">MLKELLNETVSVLAFSGVGIVLMVLGFVLVDVITPGNLRKQIWLERNRNATVLLASNLLAVGMIVFAAISASSDNLVVGISYSFVYGVIGLIVMGVAFVLLDLLTPGKLGAILVEENNHPAVWVTAATHIAVALVVMAGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8X2</accession>
    <name>D3Q8X2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016152.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0870"/>
    <dbReference type="EnsemblBacteria" id="ADD40581">
        <property type="protein sequence ID" value="ADD40581"/>
        <property type="gene ID" value="Snas_0870"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0870"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102962_2_0_11"/>
    <dbReference type="OMA" id="KYYRRTA"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="171" mass="18709" checksum="6C485F646D8B23B8" modified="2010-04-20" version="1">MSPSFAKPAFDVSTPDHFKALAHPLRHRLMFALGEPATISQLAKRLATGKGNIAHHIKVLTEAGMVHVVSTRTVRGGTEQYYQRTAARLDFASEAAETTTAASLAAVAQELIGAADDPLLVLRHLRLSPAKAARLRALLEESLDELEPDSDHDPRYGVMVTMYRQHDTDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8X6</accession>
    <name>D3Q8X6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016156.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0874"/>
    <dbReference type="EnsemblBacteria" id="ADD40585">
        <property type="protein sequence ID" value="ADD40585"/>
        <property type="gene ID" value="Snas_0874"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0874"/>
    <dbReference type="HOGENOM" id="CLU_1926278_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="131" mass="13989" checksum="6EE62CF310710DD6" modified="2010-04-20" version="1">MSGQIQVDRQALRQFVETMRQTASDMAAVRDKATAAFTGNYLDTNRTARWNGGVKVTLGVVNHAHPGRDAGEVMANRIVNTVNFVVSMEEGTRAMGGIAEAILNALDNQDQIGSAELEAIFAQSPSKPLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q928</accession>
    <name>D3Q928_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0926"/>
    <dbReference type="EnsemblBacteria" id="ADD40637">
        <property type="protein sequence ID" value="ADD40637"/>
        <property type="gene ID" value="Snas_0926"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0926"/>
    <dbReference type="eggNOG" id="ENOG5032SJC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1271629_0_0_11"/>
    <dbReference type="OMA" id="SELITWR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048962" evidence="1">
        <location>
            <begin position="26"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="217" mass="24455" checksum="BCB32F60667367CE" modified="2010-04-20" version="1">MLGAMFLIIAIVALILMAVFSHQKAKQRETERRQWAAANGFHYVPGFVNLPDASIRSPFRSSGRNSNFFEGGFHGHRARAFVHTYTTTRRDNEGRRQEQVHRYAVAAVAHAAGPNLHLDIAPQGIFGRLADKLGFGVLTGDVEFDRAFKVRSGDEFQARSVLRPEATAWISQDPRFRNSAVRFEYGWVMVWYPGHLNVGHLSLQFAFLADIASRLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q930</accession>
    <name>D3Q930_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0928"/>
    <dbReference type="EnsemblBacteria" id="ADD40639">
        <property type="protein sequence ID" value="ADD40639"/>
        <property type="gene ID" value="Snas_0928"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0928"/>
    <dbReference type="eggNOG" id="ENOG5032T0S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086041_2_0_11"/>
    <dbReference type="OMA" id="DNPYWRR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025492">
        <property type="entry name" value="DUF4383"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14325">
        <property type="entry name" value="DUF4383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="18111" checksum="F86405A59E0B6A54" modified="2010-04-20" version="1">MPSATIVGVDHLPINHHLRPLYRVLAFLTGVYILVFGILGYVKSKGLETFAQPNDADLPRVLWLDANPAFSILSIVVGAVVVLAVIVGRNVDFYVNLLAGSVFLLASMAMMALLHTDLNYLGFTMATCIASMILGLIMFTAGLYGRVGSSEREAAAEAHRHGQTVTDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9C8</accession>
    <name>D3Q9C8_STANL</name>
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        <submittedName>
            <fullName evidence="5">WD-40 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2935</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018181.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2935"/>
    <dbReference type="EnsemblBacteria" id="ADD42610">
        <property type="protein sequence ID" value="ADD42610"/>
        <property type="gene ID" value="Snas_2935"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2935"/>
    <dbReference type="eggNOG" id="COG2319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_683173_0_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="eIF2A" evidence="4">
        <location>
            <begin position="117"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="eIF2A" evidence="4">
        <location>
            <begin position="229"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="289"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="403" mass="42809" checksum="FFC23C071D42E460" modified="2010-04-20" version="1">MALLRDGGARQVGGYELGSGRDDASPAVMNQVGPNGAPMAYVPPPRPPVPLLRRRGVIVGAVAALCVIVVAALAAVIVLRPQHTSGVLDGGGTPSEAALPSYAIADERTLDPPETLNALTFSPDGKLLATGSGYSRNTQLWDVDTGEQVAELKGTSPCAQEFSPDGKLLATGGCAGEETGVQLWDVRTEDKIATITKNDSEDLAFSPDGKTLATIGNNPHDGLRLWEVSTGDEIMHLDMEDAIDFTFSPDSATFAVTPSRADLDDPFRAELWDMRSGDKISSFTVNGGTVTYSPDGKTLITASCGGTVSRWEVRTGDKVDSHRLVDCFDLSFSSDSKVLAIVNLEFEEPPGTTLWSVETGDRLLTLSTQEAYHVAFSTTGKAVAVNTSLEANTHDEIVLWRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9E7</accession>
    <name>D3Q9E7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2954</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018200.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2954"/>
    <dbReference type="EnsemblBacteria" id="ADD42629">
        <property type="protein sequence ID" value="ADD42629"/>
        <property type="gene ID" value="Snas_2954"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2954"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_1_11"/>
    <dbReference type="OMA" id="FWSQLMV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="3">
        <location>
            <begin position="17"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="590"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="668"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="915" mass="97469" checksum="9C3A02E6F2EC10B8" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Q9</accession>
    <name>D3Q9Q9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020176.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44605">
        <property type="protein sequence ID" value="ADD44605"/>
        <property type="gene ID" value="Snas_4967"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4967"/>
    <dbReference type="eggNOG" id="ENOG5034A6H">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1266250_0_0_11"/>
    <dbReference type="OMA" id="ARYEYES"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049814" evidence="2">
        <location>
            <begin position="23"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="23928" checksum="CCF7A34F16E61363" modified="2010-04-20" version="1">MNRLLTTTIGIAAIAMALTACGTDDPPGDSKDGPIDATSESEGEGIAEGDFRNAPVPTNDPKDAWEKDLPAEPDREAPLAEKIEFELVSAAAEYTHQYDDKSEVTCPDIKGDKDEDVTCEMTYFGQKVEWKVSISGGSMVARYEYESEQSVQSREFLENALRYKAQTEDVMCELDEEYTVVNPQKSEPVVCHSLKDGEQANWQLSIGARGAVTFSQKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9U0</accession>
    <name>D3Q9U0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">3-isopropylmalate dehydratase large subunit</fullName>
            <ecNumber evidence="14">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Alpha-IPM isomerase</fullName>
            <shortName evidence="14">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">leuC</name>
        <name evidence="17" type="ordered locus">Snas_4999</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 14">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 14">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:17941"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="ChEBI" id="CHEBI:57872"/>
            <dbReference type="EC" id="4.2.1.99"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="14">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 14">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="14"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020207.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4999"/>
    <dbReference type="EnsemblBacteria" id="ADD44636">
        <property type="protein sequence ID" value="ADD44636"/>
        <property type="gene ID" value="Snas_4999"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4999"/>
    <dbReference type="eggNOG" id="COG0065">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006714_3_4_11"/>
    <dbReference type="OMA" id="CNMSIEM"/>
    <dbReference type="OrthoDB" id="749418at2"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00946"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047456">
        <property type="term" value="F:2-methylisocitrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 14" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 14" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 14" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="16">
        <location>
            <begin position="11"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="422"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="423"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ADD44636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="470" mass="49789" checksum="4646C1F5D061B666" modified="2010-04-20" version="1">MTNKVPLTMAEKVWNAHTVRERAGEPDLLYIDLHLLHEVTSPQAFDGLRQSGRKVRRPDLTIATEDHNTPTDNLLTISDPVSRTQIEALRRNCEEFGVRLHPLGDAEQGVVHVVGPQLGLTQPGTTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLPQTRPKTMAVTVDGELPEGVSAKDLILAIIAKVGTGGGRGHIVEYRGSAIRSLSMEARMTVCNMSIEWGAKAGMIAPDETTFAYLRDRPHAPKGEEWDAAVAAWCQLPTDDGAVFDKEIHVDAASLSPFVTWGTNPGQGVPLSASVPSPDDFDDPSQAAAARSALDYMDLTPGTPMTDIGVDVVFVGSCTNGRIEDLRAAAEVLKGKKVADNVRMLVVPGSARVRAQAETEGLHEVFTDAGAEWRFAGCSMCLGMNPDQLAPGARSASTSNRNFEGRQGKGGRTHLVSPSVAAASAVTGRLTAPAALAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAG8</accession>
    <name>D3QAG8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018322.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3080"/>
    <dbReference type="EnsemblBacteria" id="ADD42751">
        <property type="protein sequence ID" value="ADD42751"/>
        <property type="gene ID" value="Snas_3080"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3080"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038054_0_0_11"/>
    <dbReference type="OMA" id="GFYRHAK"/>
    <dbReference type="OrthoDB" id="257710at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019026">
        <property type="entry name" value="Peptidase_M64_IgA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09471">
        <property type="entry name" value="Peptidase_M64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048809" evidence="1">
        <location>
            <begin position="31"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="422" mass="45978" checksum="1F11D8A38A7CE9A6" modified="2010-04-20" version="1">MRFRPRTIIAAVAVLGTATAVAAFTIPASADDNGEKVTESHEVFSPNGDIDRKKVTREVKDDPAPRSTVRKAEVVPILDNGPTEEKLDIVVVGDGYTEADMATYEEHTRSKMDEVFAVEPFKSYKDQFNVWMVKVVSKESGVDHDPQGTLRDTALDMEFWCGDTERLLCVNTTKAKQYAAEAPDVDQVLALGNSTKYGGAGYPSEDVGTSSGGNEQAGQVVVHEFGHSIGDLADEYTYGGGDTYTGPEVGEVNASIKDRATQESEKVKWHQWMGEETPDGGTIDTYDGCRYYEHGIFRPSDNSIMRELGREFNLPGREAMIGAFHDSAAVASPTVPTKQKVAVGEELGLELPDVHGDHTIEWKVDGKVVKSASGKTSLDTGGLKLDSGKHEVSVTVTDTTDWVRDEKLRADNLTDTFTWTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB18</accession>
    <name>D3QB18_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1125</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016406.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1125"/>
    <dbReference type="EnsemblBacteria" id="ADD40835">
        <property type="protein sequence ID" value="ADD40835"/>
        <property type="gene ID" value="Snas_1125"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1125"/>
    <dbReference type="eggNOG" id="COG1129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="KTTDITH"/>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="266" mass="28172" checksum="9BAA7C4B1D61E84B" modified="2010-04-20" version="1">MSSTPILEVSGLNKSFGPVQVLHDVHLSVHAGQVTALVGDNGAGKSTLIKCVSGIHGIDSGTIHFDEEQVRIASPRDAANLGIEVVYQDLALCDNLDIVQNMFLGREKRSGLVLDEPTMEQLAAETLETLAVRTVKSLRQHVSSLSGGQRQTVAIAKAVLWNSKVVILDEPTAALGVAQTAQVLELVRRLADNGLAVVLISHNLNDVFAVSDRIAALYLGQMVAEMETAEVTNTQVVELITSGSSGDLGLPRADSSTEYGLNGAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB85</accession>
    <name>D3QB85_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplP</name>
        <name evidence="10" type="ordered locus">Snas_1192</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016473.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1192"/>
    <dbReference type="EnsemblBacteria" id="ADD40902">
        <property type="protein sequence ID" value="ADD40902"/>
        <property type="gene ID" value="Snas_1192"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1192"/>
    <dbReference type="eggNOG" id="COG0197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078858_2_1_11"/>
    <dbReference type="OMA" id="KGAVEYW"/>
    <dbReference type="OrthoDB" id="1786618at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="9">
        <location>
            <begin position="11"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD40902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="141" mass="16084" checksum="80C26354A77D7293" modified="2010-04-20" version="1">MLMPRKPPKGFRKPHHPKRRGRAKGGTRVTFGEFGIQALEPAYVTNRQIESARIAMTRHIKRGGKVWINIFPDQALTKKPAETRMGSGKGSPEWWVANVKPGRVMFELSFPNETIAREAMRRAIHKLPMKCRIVTREVGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB93</accession>
    <name>D3QB93_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplF</name>
        <name evidence="7" type="ordered locus">Snas_1200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016481.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1200"/>
    <dbReference type="EnsemblBacteria" id="ADD40910">
        <property type="protein sequence ID" value="ADD40910"/>
        <property type="gene ID" value="Snas_1200"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1200"/>
    <dbReference type="eggNOG" id="COG0097">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065464_1_2_11"/>
    <dbReference type="OMA" id="KPDPYKG"/>
    <dbReference type="OrthoDB" id="1398618at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_B">
        <property type="entry name" value="Ribosomal_L6_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019906">
        <property type="entry name" value="Ribosomal_L6_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002358">
        <property type="entry name" value="Ribosomal_L6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF14">
        <property type="entry name" value="PTHR11655:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00059">
        <property type="entry name" value="RIBOSOMALL6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03654">
        <property type="entry name" value="L6_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00525">
        <property type="entry name" value="RIBOSOMAL_L6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="11"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="92"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="179" mass="19580" checksum="F3E2B5773B195368" modified="2010-04-20" version="1">MSRIGRQSIPVPGGVEVTIDGTDVKVKGPKGELSRTLVEPITIEKNEDGSLQLNRPDDDRRSRAMHGLCRSLVNNMVIGVSEGYKKSLEINGTGYRVQQKGSNLEFALGFSHPVVIEPPDGVKFSVEKPTLFHVEGIDKQVVGEIAANIRKIRPPEPYKGKGVKYVGEHIRRKAGKAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBH7</accession>
    <name>D3QBH7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3189</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3189"/>
    <dbReference type="EnsemblBacteria" id="ADD42859">
        <property type="protein sequence ID" value="ADD42859"/>
        <property type="gene ID" value="Snas_3189"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3189"/>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_9_0_11"/>
    <dbReference type="OMA" id="RQRDPWP"/>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="6">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="5">
        <location>
            <begin position="111"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="320"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="345" mass="36791" checksum="92B02C364461A7F5" modified="2010-04-20" version="1">MDFSVAVELFFQSRAPRKDSPHTTAAYRRDLLAVAEVVAAEVGCETGRVDCGGLSVSVMRRAFAGFSASRAKSSIGRAWSVWNAFFSFLVGEGIVEGNPMSGVARPKAARPLPKPLRGEDAPDRLLEALMSGARAGRHPWPQRDVAVVAVLLLTGLRSSELLALRAGDVAGGAGERRLVVRDGKGGADRVVPVEGPLEVLLADYLASRRGRFPGGRWPLAPSEPLFVDHRGEALTRNQLQYLVRQCYRFAGVDDAVQRGALVHALRHTFATRVGASGASAMEVMELLGHRSLNASQGYLGVTGRELRDAARSNPGYGVLGRLVDRRSGQQRGDGVDGGGVADDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBI2</accession>
    <name>D3QBI2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018435.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3194"/>
    <dbReference type="EnsemblBacteria" id="ADD42864">
        <property type="protein sequence ID" value="ADD42864"/>
        <property type="gene ID" value="Snas_3194"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3194"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_997172_0_0_11"/>
    <dbReference type="OrthoDB" id="1308416at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="279" mass="30727" checksum="2DA40A223949A58C" modified="2010-04-20" version="1">MTSDSTWDGVAIGTGHPRGSAIVTRRHTPDGWQYLTLHRANRPSDDPDGLWAWTPPSGMRQPGEGAYTSALRELAEETGITDATIHPIDLARGHALWLATVDADQEVVLDHEHDRYEWLDADAAAKRCRPGVAAETITTAATIPDTTFTFTPNPDNPTSGIYGITVDNQERGTAQHHAITDNPTFFDIVGHTDAAVIECVVTDTAIRADGLEPRLIWSFVRDIVLPAYQNVTTVWTVTDADHTRRLRSYMQAGFTHDVTVEVVPGRPKAVCGLRLAQWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBK9</accession>
    <name>D3QBK9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3221</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018462.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3221"/>
    <dbReference type="EnsemblBacteria" id="ADD42891">
        <property type="protein sequence ID" value="ADD42891"/>
        <property type="gene ID" value="Snas_3221"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3221"/>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_9_6_11"/>
    <dbReference type="OMA" id="IMPHDFR"/>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="136"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="306"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="337" mass="36389" checksum="112C0144F046C196" modified="2010-04-20" version="1">MEQLPLPSHRAEDVAEKKTPHRDGAVAGVGDPVATYLGSLASPASRREMAACLNRIVRLSTGDDNATAAGQPWHKLTYRDTARLKETLCQQGWSAAHVNKHLVALRRVLTEAWRLGLMDAEQKDRACDIADVTSVRLPRGHHVAAEVIGAVLAACDADEAAAGRRDAAIIAVLYSTGCRRAEIAGLRLRDYDPAERGITVIGKGDKQRLVHLNAQAVAKVEAWLAVRGRGDGAMFSPISAAGRIRMRDGVPAGMSGQAIGHMLTRRLRQAGAPQASPHDLRRTFIGSLLDAGVDLATTQAIVGHASPATTARYDRRPDHRRREAIDRLELPQAKPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBQ0</accession>
    <name>D3QBQ0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gluconate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3262</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018503.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3262"/>
    <dbReference type="EnsemblBacteria" id="ADD42932">
        <property type="protein sequence ID" value="ADD42932"/>
        <property type="gene ID" value="Snas_3262"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3262"/>
    <dbReference type="eggNOG" id="COG2610">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027949_0_2_11"/>
    <dbReference type="OMA" id="PPAYGML"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015128">
        <property type="term" value="F:gluconate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003474">
        <property type="entry name" value="Glcn_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30354">
        <property type="entry name" value="PTHR30354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02447">
        <property type="entry name" value="GntP_permease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002746">
        <property type="entry name" value="Gluconate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="298"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="335"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="412"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="457"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="482" mass="49363" checksum="4862B366A1158766" modified="2010-04-20" version="1">MDLQLLAALLLGIAAVVIIVLRTRLDAFVGLLVACLVTGFVAGSTPTDILTAITEGFGTTLGSIGIVIGLGVALGKILEVSGAADALARAFTRAFGDGREAWAMASTGAVVSIPVFCDSAYVIMNPLARSIARRKRAGYVTLALALGCGMTLTHHMVPPTPGPLGVAGILGADLGMIILVGLVFSVILLPIVVVYARWIGPKLEKSVLPEVREKVYATVASGGTGGTTSDNGGEAPAESPLGTPPEGAKPRRMNAWLASLPLVIPLLLIVINTVGTAIDKSNQNVLGDDEAYEPSRWAAILAFIGSPVVALMLGLALAVYVLLPRWTRRDKVSGWLADAAASAGLIILITGAGGAFGQVLRSTGVGDELAKVIASWSLPGVLVPFLVATLVRLAQGSGTVAMITAASVTAPLIAGLGISPVAAAMACCAGSMVFSYFNDSYFWVVTRFTGLDGTAALRAWSGITTAVWLGSIPLLLIASAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBT5</accession>
    <name>D3QBT5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5189</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5189"/>
    <dbReference type="EnsemblBacteria" id="ADD44824">
        <property type="protein sequence ID" value="ADD44824"/>
        <property type="gene ID" value="Snas_5189"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5189"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_1_1_11"/>
    <dbReference type="OMA" id="NAKAWLF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014293">
        <property type="entry name" value="RNA_pol_sigma70_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02947">
        <property type="entry name" value="SigH_actino"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="85"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="189"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="263" mass="29672" checksum="7AE1AD49BBAEF19A" modified="2010-04-20" version="1">MMASTRERVENEDTQRLRRLLSAPEWPLDGGETTAASPIPAPARHSGAVPSAKQATRGEPVTDEEQAETAAEKRARFERDAMPLVDQLYGGALRMTRNPQDAEDLVQETYLKAFSAFHQFKAGTNLRAWMYRILTNTYINSYRKRKRQPVQSPTEEITDWQLVSAESHTSTGLRSAETEALDRLPDSDVKDALARLPEEFRLAVYLADVEGFAYKEIAEIMGTPIGTVMSRLHRGRRQLRDMLAEYAAQRGFSASDDHEEVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTX1</accession>
    <name>D3PTX1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA gyrase subunit B</fullName>
            <ecNumber evidence="10">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gyrB</name>
        <name evidence="12" type="ordered locus">Snas_0006</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the type II topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015300.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0006"/>
    <dbReference type="EnsemblBacteria" id="ADD39729">
        <property type="protein sequence ID" value="ADD39729"/>
        <property type="gene ID" value="Snas_0006"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0006"/>
    <dbReference type="eggNOG" id="COG0187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006146_4_1_11"/>
    <dbReference type="OMA" id="LWETTMH"/>
    <dbReference type="OrthoDB" id="205481at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034335">
        <property type="term" value="F:DNA negative supercoiling activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03366">
        <property type="entry name" value="TOPRIM_TopoIIA_GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01898">
        <property type="entry name" value="GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011557">
        <property type="entry name" value="GyrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034160">
        <property type="entry name" value="TOPRIM_GyrB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01059">
        <property type="entry name" value="gyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="11">
        <location>
            <begin position="431"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD39729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="656" mass="73363" checksum="26EC2C57CE8F2E65" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU11</accession>
    <name>D3PU11_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Alpha-amylase</fullName>
            <ecNumber evidence="7">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_1247</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1247"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40957">
        <property type="protein sequence ID" value="ADD40957"/>
        <property type="gene ID" value="Snas_1247"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1247"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013336_0_0_11"/>
    <dbReference type="OMA" id="HPWWEVY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031319">
        <property type="entry name" value="A-amylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006046">
        <property type="entry name" value="Alpha_amylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00110">
        <property type="entry name" value="ALPHAAMYLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00632">
        <property type="entry name" value="Aamy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049223" description="Alpha-amylase" evidence="8">
        <location>
            <begin position="28"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Aamy" evidence="10">
        <location>
            <begin position="45"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Aamy_C" evidence="9">
        <location>
            <begin position="409"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD40957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="494" mass="52733" checksum="422BD0CDC14F6B48" modified="2010-04-20" version="1">MRTKNLIPPMVVITVLATGFTAGVAQSEPGQPSTVEATAPIAGDEAILHLFQWPWKSVASECTNVLGPAKFPAVEVSAPQEHVVLPDKQYPWWQDYQPVSYQLESRRGSAKDFADMVSACDDAGVEVYVDTIVNHMAGGASTGTGSGGSEYSQYDYPAVPYGNNDFHHCGRNGNDDIQNWQDQWEVRNCELLDLSDLATETEHVRKQLTGYMQDLIDLGVDGFRIDAAKHVPVADLEAIYGGLTGDPKIFQEVIEGGNGEISPNEYKGLGRVTEFRYGDQVGARFKDGQLSALKDFQSQMLLDSSAATTFIDNHDTQRSGRAQLTYKNGARYYMAEAFALAHGYGSPHILSGFAFDNADAGPPAESDGTTKQAVADDGACASGWECSHRQRAVLNLGAFRTAAGDAAVTDWWSNGSDQIAFGRGDRAFAAFNASGSALTTEFATALPDGEYCDVANGDHTDGACDGPAYTVSGGKLTATVPANGVLAVHVNAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU57</accession>
    <name>D3PU57_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inositol monophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1294</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1294"/>
    <dbReference type="EnsemblBacteria" id="ADD41003">
        <property type="protein sequence ID" value="ADD41003"/>
        <property type="gene ID" value="Snas_1294"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1294"/>
    <dbReference type="eggNOG" id="COG1218">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071517_0_0_11"/>
    <dbReference type="OMA" id="NTCYYAN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="282" mass="29944" checksum="5BA35329902DE3F0" modified="2010-04-20" version="1">MLDQSDAALARSLAQQAGQELLLLRDKLGFGDATVLRREGDQRAHEFLMSALAEFRPGDAILSEEGKGEQGRTGASRLNAERVWIVDPLDGTREYAEAGRDDWAVHVALWERGTLSAGAVALPAQDTVLGADAPPTPLPPQGRIRMVVSRSRPAAFLTALAEVIDAELVPMGSAGAKTAAVITGKVDAYVHAGGQYEWDSAAPVAVARAAGLHTSRIDGTDLTYNNSDPKLSDLVVCRPELSALILKGIAAVRLHPLPTQGSINQFIKGGADERLRLSRQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU92</accession>
    <name>D3PU92_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016609.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1329"/>
    <dbReference type="EnsemblBacteria" id="ADD41038">
        <property type="protein sequence ID" value="ADD41038"/>
        <property type="gene ID" value="Snas_1329"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1329"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061176_1_0_11"/>
    <dbReference type="OMA" id="FNYGEGK"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="300" mass="32321" checksum="BD675AFCD74BEDA5" modified="2010-04-20" version="1">MDVCVIGGSRYFGKRLIERLLAADARVTVVNRGSAPAPAGATRLVADRSDEGRLLAALGDRTFDVVVDQVCYTPTQAAVAASVFADRTARYVMTSTVEVYAGIARPGAGAALSESSVSLDPSIMDFAAPWDDEDYLEAHYGEAKQQAEAVFTAKAPFDFASVRSAHVLGGGAEDFTGRLAHYVDRVRAGEPVDVHAPEFAATFINVDEIAEFLAWAAFADFTGPVNAASHGELTARQLTESIPSEAPPRFRTVAPDTTASPYSFPTYYAMDNSRAERLGFRFSRLTDWLPDAIGELTHER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUB3</accession>
    <name>D3PUB3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016630.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1351"/>
    <dbReference type="EnsemblBacteria" id="ADD41059">
        <property type="protein sequence ID" value="ADD41059"/>
        <property type="gene ID" value="Snas_1351"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1351"/>
    <dbReference type="eggNOG" id="ENOG50332IC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145468_1_0_11"/>
    <dbReference type="OMA" id="FGAWVVE"/>
    <dbReference type="OrthoDB" id="1889547at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="115" mass="12720" checksum="E4B41D0508DA316E" modified="2010-04-20" version="1">MELLRHALLYIHLLGFAMLFGGWLTAFLSDRLKINPVMLWGSVIQLATGIFLSAPFPKDYEPNYAKIGVKAVLAVLIAVMVWIPHLKKRESTAKGHFIAIGAMVVVTAGVAVFWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUD1</accession>
    <name>D3PUD1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018515.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3274"/>
    <dbReference type="EnsemblBacteria" id="ADD42944">
        <property type="protein sequence ID" value="ADD42944"/>
        <property type="gene ID" value="Snas_3274"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3274"/>
    <dbReference type="eggNOG" id="COG0154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_0_3_11"/>
    <dbReference type="OMA" id="MHEGALG"/>
    <dbReference type="OrthoDB" id="1239251at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="459" mass="48469" checksum="AF90426065948CC8" modified="2010-04-20" version="1">MDNGRYGSLTETARALREGRTTSVALVERAIEAARTHGELLGTYVTRFDDAALEAARRADRELAAGRDRGPLHGIPLGVKDLIATSEAPTTAQSRVRAAAVEPDAAVVARIRAGGGVICGKTTTMEFGCGVPDLSGPFPVPRNPWDTDRWAGGSSSGSANGVAAGCFAAGIGSDTAGSIRMPAAFCGVTGLMPTYDRVPRAGCVPLADSLDRLGPIARDARDCAAVMEVIGSLPPPDFDADLAGLRVGVSRDWTAAGDLTAAFESAVDVWEGLGVRLVDIDLPLLPELTTAVIVTAVSEGFVRHQADLPARWHDYLPTTRALLATATFMSGADYAQAQHVRRAAGRRLRELFGRVDAIVSPTALIPAPLLDTLTNEYGQQNDDAILSRINTPYWNGVANPVLAVPIGFDSAGLPLSMQIAGACDDEETILRLGAAYQGATDWHRREPFDTNRNDHVHNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUD9</accession>
    <name>D3PUD9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3283</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3283"/>
    <dbReference type="EnsemblBacteria" id="ADD42952">
        <property type="protein sequence ID" value="ADD42952"/>
        <property type="gene ID" value="Snas_3283"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3283"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="AIITGRM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="18"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="354" mass="38443" checksum="A460719EE62FC909" modified="2010-04-20" version="1">MNTPSPKSTPAPGKRHRYSMSDVAARAGISVGTVSNVLNHPERVAEETRRRVREVIDTLGFIRNAPAMNLRSGSSAAVGVVVLDIANPFFTEVLRGAEDRLADEGLLLIVCSSDDALDKEEHYLRVLEEHRVQGMLITPAMADLNPLVDLRNRGLGVVLLDRTEADGKLCAVAVDDVRGGELAGEHLLSLGHRRIAFLNGPLSLRQCAERREGLRRAVTTAGLDPDGVLTEIELPSLNAQGGEAAIRELGRDLPTAVFCVNDLVALGALRALDQRGIVVPDQISLVGYDDVEFTAMLSPSLTTIRQPKYQLGKAAAELFLIDARQDDDHWHQQTVFQPELIVRDSTTASQRASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUH2</accession>
    <name>D3PUH2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, GntR family with aminotransferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3319</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018556.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3319"/>
    <dbReference type="EnsemblBacteria" id="ADD42985">
        <property type="protein sequence ID" value="ADD42985"/>
        <property type="gene ID" value="Snas_3319"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3319"/>
    <dbReference type="eggNOG" id="COG1167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_1_11"/>
    <dbReference type="OMA" id="PGLVMGF"/>
    <dbReference type="OrthoDB" id="1320028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="21"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="470" mass="50743" checksum="55DA88F236EA0934" modified="2010-04-20" version="1">MPDPWYAIRELLLADDAVDHGKRGRRTERALREAIRSGRVPPGTRLPSSRDLARQLDVARGTVTAAYRQLTAEGYVSTRPGSGTYVAASSGPGPVAEPAAAPTRYPAFEFDLRTGIPALSDFPRTAWLAATKRALAELPDAALAYPDTAGLPSLRQELTAYLGRVRAVTTTADGVLVTHGAAEALALLARALRDAGHRRIAVEDPCYPGQVELLSGNGLEPVPVPVDDAGLDVEALRRTGCRAVVITAAHQYPLGVVLQPRRRLALLEWAADNDALIVEDDYDAEHRYDRPAVAALQGLAPTRVAYIGTTSKTLAPGLRLGWLVAPARFHRDVLRGKDVLNRGGSVIEHAAFATFLRHGGYDRHLGRTRRMYRQRRDALVEALATRLPHWRPTGVAAGLHVVVRLPPNTSDSTLAARLADAGVNVIALSRYMRTDTLPFPGLVIAYAATTPDRLRAAVDRMAQVTTTSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUK8</accession>
    <name>D3PUK8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018592.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3356"/>
    <dbReference type="EnsemblBacteria" id="ADD43021">
        <property type="protein sequence ID" value="ADD43021"/>
        <property type="gene ID" value="Snas_3356"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3356"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_0_1_11"/>
    <dbReference type="OMA" id="QWGERFL"/>
    <dbReference type="OrthoDB" id="1919329at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="150" mass="16740" checksum="2E7976A5BC3B89F3" modified="2010-04-20" version="1">MDVTLATGGTWTDAACPVARTTDLVGDRWSLLIIRDAMDGASTFTDFQRGLGIARNILTDRLRKLVEHGILDKSDAADGRRYNYRLTEAGRDLFTVVVALRQWGERHAFAADEPHSTLVDGQERELSELRALNRDGQPVTVESSRVRKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUN4</accession>
    <name>D3PUN4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018618.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3383"/>
    <dbReference type="EnsemblBacteria" id="ADD43047">
        <property type="protein sequence ID" value="ADD43047"/>
        <property type="gene ID" value="Snas_3383"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3383"/>
    <dbReference type="eggNOG" id="ENOG5031XFU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_737522_0_0_11"/>
    <dbReference type="OrthoDB" id="1968226at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="383" mass="41562" checksum="DC0AC3367629284A" modified="2010-04-20" version="1">MTNHVPEAESAPPDEEPSPPDPRRRKLLVGGTVLAVLVALFGVIAWVDDSTSPEAVVEDFFDAIVDKDVEGALSLVAWDGYGVPFGEQAIFMHPDAIADGWELLEAKLSATEDSYGEERVDVTIGNDKKRVDGTITLSDASGEWKIVDPFVSVTMPMGSLTYIQVNDKTVVADELFGYDAGRGSPTEYKLLPGLYTFFGDLNGTSTEPEPGELMLPEDDAQAMAVSPPVLELTDTAQDDVQEGVNKLVDDCATFKVRQPALCPFGVDSYYRTDDEEYHDIHDVTWKVKEYPRVRVTGSLLNNHYWPGLEVVVNDPGVIKLTAAASNFDDGDVKLTAECEVSGEYLRVVLGPDGEPRVNPEVFDGYGLAPQSGFGIDTCGSEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUT5</accession>
    <name>D3PUT5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020530.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5325"/>
    <dbReference type="EnsemblBacteria" id="ADD44959">
        <property type="protein sequence ID" value="ADD44959"/>
        <property type="gene ID" value="Snas_5325"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5325"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_3_0_11"/>
    <dbReference type="OMA" id="EQTIRCQ"/>
    <dbReference type="OrthoDB" id="1626703at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="147" mass="16381" checksum="77987441DA0B9448" modified="2010-04-20" version="1">MNDELKLRDQVCFALYSATRAITGLYRPLLDELGLTYPQFLVLLVLWESEPRTVSELGAALRLDSGTLSPLVKRLETMGYLVRRRDTTDERRVLVELTDSGRAVRPQVRDVPQQVAEAAGISTAELLALRDTLTAITDSIHSGNRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV03</accession>
    <name>D3PV03_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5395"/>
    <dbReference type="EnsemblBacteria" id="ADD45027">
        <property type="protein sequence ID" value="ADD45027"/>
        <property type="gene ID" value="Snas_5395"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5395"/>
    <dbReference type="eggNOG" id="COG3000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033631_3_2_11"/>
    <dbReference type="OMA" id="QPDYPRD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="2">
        <location>
            <begin position="115"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="295" mass="32060" checksum="63F18A7410275891" modified="2010-04-20" version="1">MTTRTLKPLVRYGYAPAMLLGVNGAGIAIASAGAPKAWLLGLLGLAVALSFAAERVLPYEDTWNHDHGDTRRDTIHTFVNETLILASVAAIPALAILTPGDGIWPHHWPFVLQVLAAILAADLGITLIHYASHKIDALWRFHAVHHSAKRFYGLNGLMKHPLHQTIEMAAGVAPLILIGLPASVASTLALAVAVQLLLQHSNADYRVGALKHVLALNEGHRFHHLKWAGIGDVNFGLFTLAWDYLLRTKTYDPHRRFTSEILGMAAHPDYPTAYLPQLAEPFRASGACTTDDTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVM2</accession>
    <name>D3PVM2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase FAD/NAD(P)-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3472</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="1">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018707.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3472"/>
    <dbReference type="EnsemblBacteria" id="ADD43136">
        <property type="protein sequence ID" value="ADD43136"/>
        <property type="gene ID" value="Snas_3472"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3472"/>
    <dbReference type="eggNOG" id="COG0543">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_1_1_11"/>
    <dbReference type="OMA" id="NTARYGK"/>
    <dbReference type="OrthoDB" id="1109542at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012165">
        <property type="entry name" value="Cyt_c3_hydrogenase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006816">
        <property type="entry name" value="Cyc3_hyd_g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR006816-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="274" mass="29018" checksum="EF948D0E7F830D3F" modified="2010-04-20" version="1">MESAVPTLPLRYRITAKTSHSPDTVSLRLSPAEESLPVFAAGQFAMLYAFGIGEIPISVSDGCDGGDLTHTIRAVGKVSQALHDAAVGSIVAVRGPFGRGWTLPAEPGRDVLIVAGGVGLAPLRPTIVAAARQRDNFGHVSVCAGAGGPSGLLFTAEYDDWRRAGLDVRVTVDRPGPGWSGRTGLVTSMFDEVDFAPGRTTALLCGPEPMMRAAARDLIARGVRDEDIQVSLERQMRCGTAECGHCQLGPLFICRDGPVVDYRLARPLLSVEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVQ3</accession>
    <name>D3PVQ3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018738.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3504"/>
    <dbReference type="EnsemblBacteria" id="ADD43167">
        <property type="protein sequence ID" value="ADD43167"/>
        <property type="gene ID" value="Snas_3504"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3504"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_12_11"/>
    <dbReference type="OMA" id="PLNFDLC"/>
    <dbReference type="OrthoDB" id="377638at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="104"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="475" mass="50972" checksum="431AC68A0D3ACB41" modified="2010-04-20" version="1">MTSPSLIDDFKDARRALADRVCVRSGATVRTFGEITETARRLVAAFDRNGVSRDSVVEVEGVPGPGLLSALLAMLSCSVPFQLVTPPRTRAVDPFDDTAVFLRVNGDRVPLTALADANPSTRDLPSPAITGDTPAYLIETSGSTGDRKRVIGSYTGLSRFLRWERDTFHIGGDDRVAALTSPTFDVSLRELLLPFATGAELVVPHRWPLSPGRITPFIAETAATVVNVVPSLAAYATSTHPTVTAPSLRLTLFAGEMLPHTTVRAWQRFAPHSATVNLYGPTETTLAQFANVIDEPVPGIQPVGFPLPGTSFRIVDGEVVIATPNGSLGYADEPATDRLIRDGGMTTFATGDLGRVEPDGALMLLGRRDDRVKVRGIWVNLTDVEQTLRDALNREEIAVVTSPNPLGVDIVAVIAGSERHIDKALLVKTIAHRCGSAAIPSAYRFVPRLPRLASGKIDRRRCRSLAVDPAAQPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVT3</accession>
    <name>D3PVT3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020625.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5422"/>
    <dbReference type="EnsemblBacteria" id="ADD45054">
        <property type="protein sequence ID" value="ADD45054"/>
        <property type="gene ID" value="Snas_5422"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5422"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1336839_0_0_11"/>
    <dbReference type="OMA" id="GELLMEW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="205" mass="22016" checksum="FC5A7A730A4097EB" modified="2010-04-20" version="1">MTGIEGEGHTPPSSVARHRLRQLRDRLGLTVDDVVERCRRLGATDVTDNIIWNIESGRRKLSLDVTVTLAAALGVPFMSLLVPDDPDATIHATPAVPVSPNRFAAWSTGTAPLPGADAGAFAEAAADLPLPGREPEDVDWQSRVRWAITHIDDHAETAAQKLNQSARDFLTAFEVVATESPSAKDALSLLQRRLGSTPDASKDDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVT4</accession>
    <name>D3PVT4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5423"/>
    <dbReference type="EnsemblBacteria" id="ADD45055">
        <property type="protein sequence ID" value="ADD45055"/>
        <property type="gene ID" value="Snas_5423"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5423"/>
    <dbReference type="eggNOG" id="ENOG5033P4S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_178607_3_1_11"/>
    <dbReference type="OMA" id="RGAYPCK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="88" mass="9276" checksum="85BD42B6CFBFD9E0" modified="2010-04-20" version="1">MSTTRIPRKALVWTRERVLSLGSTTTVETAGAVLGIGRTLAYQLAANGNFPVTVFRAGHLYRVPVGPLVALLWPDATPASNDVNGGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW01</accession>
    <name>D3PW01_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_5491</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020693.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5491"/>
    <dbReference type="EnsemblBacteria" id="ADD45122">
        <property type="protein sequence ID" value="ADD45122"/>
        <property type="gene ID" value="Snas_5491"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5491"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_658738_0_0_11"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048405" evidence="7">
        <location>
            <begin position="27"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="8">
        <location>
            <begin position="50"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="358"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="381"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="417" mass="41884" checksum="8C0081FCBF2E9AEB" modified="2010-04-20" version="1">MRVLRAVAALAVASGTVLAVPATAHADDVRARQWYLTTLDLLEAHKEATGEGVRIGLVDSGIDPSHPDLEDVVVEGEVFGQPTNEQGGNGTADAAILAGRGHGESDGVLGVAPGAEIVSADIAGARQDGQGALVADAIMFLTEKKVDVIAVAVSAPADEKLRVVVQKAAKKGIPVVVAASDTGDSALPYAGIVNAVGSDKDGKPAATDTPVPGEGDADTIAAPSQDLPMALPGGEYGTGSDTSFAAQIIAGTMALVKQKQPELKGEELITAVRDTASGRGKFDEELGYGIVNPTQALKAGATTSGGAASGGVLDGGNTTLALLIAVLGVLGLAALVLIVRLRDRSHRLALLAAPAAPGMSHTGAMPRISTAPPVASGDTGNMPRISDTGTFPRVTDTPPGGTPTPQTPPYGQNRPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW23</accession>
    <name>D3PW23_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5513</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020715.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5513"/>
    <dbReference type="EnsemblBacteria" id="ADD45144">
        <property type="protein sequence ID" value="ADD45144"/>
        <property type="gene ID" value="Snas_5513"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5513"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="QMTEVII"/>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="33"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="67"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="353" mass="38360" checksum="E5D37AA9F3E2EDE0" modified="2010-04-20" version="1">MSTEESTWSADAAGDSFVADLPGYDSDAPLLTVEQLQVEFHTREGIAKAVNGVDFTLDECRTMAIVGESGSGKSVTSQAIMGILDIPPAKVAGGRVLFRGVDLLKLKPKDMRRVRANHIAMVFQDALSALNPVWTVGYQLGELFRVHRGTSRAEAKRRAIELLDLVRIPAARQRVDEYPHQFSGGMRQRVMIAMALALDPEILIADEPTTALDVTVQAQIMRLLGDIQAERNMGLILITHDLGVVADVADDVTVMYAGRAVEQAGIDEIFEAPAHPYTKALLRSIPRLDVKGQRLEVIAGLPPVLTNIPPGCAFAPRCHYAQDMCTRAVPPLAPVDPGRTAACYFAQEVKNDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW67</accession>
    <name>D3PW67_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Nicotinate phosphoribosyltransferase</fullName>
            <ecNumber evidence="4 9">6.3.4.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Snas_1520</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + nicotinate = ADP + diphosphate + nicotinate beta-D-ribonucleotide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36163"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32544"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1.</text>
    </comment>
    <comment type="PTM">
        <text evidence="9">Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the NAPRTase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.21" evidence="4 9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016795.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1520"/>
    <dbReference type="EnsemblBacteria" id="ADD41224">
        <property type="protein sequence ID" value="ADD41224"/>
        <property type="gene ID" value="Snas_1520"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1520"/>
    <dbReference type="eggNOG" id="COG1488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025154_3_0_11"/>
    <dbReference type="OMA" id="VYFPGSP"/>
    <dbReference type="OrthoDB" id="241792at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004516">
        <property type="term" value="F:nicotinate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040727">
        <property type="entry name" value="NAPRTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007229">
        <property type="entry name" value="Nic_PRibTrfase-Fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006405">
        <property type="entry name" value="Nic_PRibTrfase_pncB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11098">
        <property type="entry name" value="PTHR11098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17767">
        <property type="entry name" value="NAPRTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000484">
        <property type="entry name" value="NAPRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01513">
        <property type="entry name" value="NAPRTase_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7 9" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NAPRTase_N" evidence="11">
        <location>
            <begin position="13"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="10">
        <location>
            <begin position="142"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD41224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="432" mass="45675" checksum="CBBD5F8A86DF5FEE" modified="2010-04-20" version="1">MPNSAQSSQPVSLMTDHYEFTMVSAALSDGTAERPCVFEVFARRLPTGRRYGVVAGIGRLAELLPGFRFSEADVEFLRSNGVVDEATARWLADYRFGGDIDCYNEGELFFPGSPILTVSGTFAECVLLETLILSVLNHDCAIAAGAARMVTAARGRPLIEMGSRRTHEDAAMASARAAYLAGFTTTSNLAAGRRYGIPTAGTSAHAFTLLHNDEQAAFASQVAKLGVDTTLLVDTYDITQGIRNAVAAAGTRLWAIRIDSGDLDVMAHHSRQLLDSLGATDTKIVVSGDLDEYAIAALAAAPVDIYGAGTAVVTGSGAPTANLVYKLVEVDGSPVVKRSENKATVGGRKTAVRRHKPTGTVVEEVVVSQGTPEPQPGDRPLQRALVRGGELVADLPGLDDSRELLRQGLIAIPWEGLKLSPGDPSVPVVMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWG0</accession>
    <name>D3PWG0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RDD domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1614</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016888.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1614"/>
    <dbReference type="EnsemblBacteria" id="ADD41317">
        <property type="protein sequence ID" value="ADD41317"/>
        <property type="gene ID" value="Snas_1614"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1614"/>
    <dbReference type="eggNOG" id="COG1714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054176_0_0_11"/>
    <dbReference type="OMA" id="HERTPHA"/>
    <dbReference type="OrthoDB" id="1974702at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="7">
        <location>
            <begin position="26"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="298"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="323" mass="34213" checksum="FE942EB7F85A228E" modified="2010-04-20" version="1">MSDISADPGLSGRLVSGEAVELDVRVARLGSRVLAFGIDFTISVIAAAIFYVVSMLLLYTLAASTSLVDEALLVAIITIDMVLAFVGVPATIETLSKGRSLGKLAVGLRVVRDDGGPIRFRHALIRALSAFAVEFPGLLLPGISWFAALGVMLIHPSGKRFGDLSAGTIVIHERTPHARIWVPIMPPGLAGWAAVTDLTALDDNLALSIRHFLARNHEIAEPARTKLGLALAAELNSFVVPPPPPGTPGWAFLAAVLSERYRRASSRLAASRAVTAQVWDTLYGPHQGQAMWTHAPPPVWTAPPTTLPQVPAAPAHPATPGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWJ2</accession>
    <name>D3PWJ2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2263 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018785.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3552"/>
    <dbReference type="EnsemblBacteria" id="ADD43214">
        <property type="protein sequence ID" value="ADD43214"/>
        <property type="gene ID" value="Snas_3552"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3552"/>
    <dbReference type="eggNOG" id="COG4295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024412_4_1_11"/>
    <dbReference type="OMA" id="AHRDPFY"/>
    <dbReference type="OrthoDB" id="1481953at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012664">
        <property type="entry name" value="CHP02452"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019261">
        <property type="entry name" value="PARG_cat_microbial"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10021">
        <property type="entry name" value="DUF2263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014899">
        <property type="entry name" value="UCP014899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02452">
        <property type="entry name" value="TIGR02452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2263" evidence="1">
        <location>
            <begin position="9"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="270" mass="29705" checksum="1B97D2847E3DD91F" modified="2010-04-20" version="1">MSGRLRHIARETVDIAETGEYRNAAGELVDIRDHVADAISGTRHYLPDDHLDVAQSPRSAPTIEVTDETTLTAARRLDTEGNTDTACLVFASAKNPGGGFLGGAKAQEEDLARCSALYRCQTTVPAFYEHHRLTRDLRYSDRVIYSPGVPVFRDEALKLLDAPYRTAFLTAAAPNLGAITRNQPQYVDDVPHALRRRASRVLAVAAAQGHRNLILGAWGCGVFRNDPRQVAEAFAEGLREVDRFDRVVFAVLDNRPQTPVRSAFTEVLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWK5</accession>
    <name>D3PWK5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3565"/>
    <dbReference type="EnsemblBacteria" id="ADD43227">
        <property type="protein sequence ID" value="ADD43227"/>
        <property type="gene ID" value="Snas_3565"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3565"/>
    <dbReference type="eggNOG" id="ENOG5033C4C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_542795_0_0_11"/>
    <dbReference type="OrthoDB" id="2084575at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="417"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="454"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="478"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="502" mass="53085" checksum="5B03B4B7D565CD0A" modified="2010-04-20" version="1">MAEPGSPMADDVLERRYRRLLFAYSAEFRTRNGDELVTTLMDCAKPGQRVPRPSEAIDLIASGLRQRLGLNMIPGFPEGLANAAPIALALATGLAAHVWWQLEPTGPHSGFRTLGLLAFAVWLLAGLAAALPSRRVARAAIGFALTVTIVVIPVLAALTTYDRPPLWVLMALAGFGAIAFGGTGVAAGAPTCLPVDIRLAVPAGAVAFAATAWAITQAFPPNAGDYYEPLITRVGMVATATVLTVAAIATVRLLLRRTDGNWWLWTAALLGVPTGWLGPFDTFGDMTAAGAFPHFGRLAQVLFATCIAAATLWWLARSRVTAKRSGSPRTLAQAGAITIGCAAGLSFGIPVIVGATPWPVTATSIVLVVAGLAAWTPSRAVHHWAALLGSAVVTVPVTWLVAVYANDWSTRDWNDPAYTATLVATVAFVPLTIGALAAVRVLRHHPTSTHEPRWAPILVVVVSVGWLSLWTLPHLPSWGPAMLALASCVAAPWLSRRRHTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWZ3</accession>
    <name>D3PWZ3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020788.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5587"/>
    <dbReference type="EnsemblBacteria" id="ADD45217">
        <property type="protein sequence ID" value="ADD45217"/>
        <property type="gene ID" value="Snas_5587"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5587"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_13_3_11"/>
    <dbReference type="OMA" id="VMNHGWI"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="116" mass="12818" checksum="DB858016BE188752" modified="2010-04-20" version="1">MSIRRAVPDILTDDMDATRAFYAGLGFEEAMDLGWVVTMASTSNPTAQVIFFDRARVEGPQPDMSVEVDDVDAVHAAMTATGAEIVYSLRDEPWGVRRFFVRDPNGRVVNVVTHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXD0</accession>
    <name>D3PXD0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1693</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016964.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1693"/>
    <dbReference type="EnsemblBacteria" id="ADD41393">
        <property type="protein sequence ID" value="ADD41393"/>
        <property type="gene ID" value="Snas_1693"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1693"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_61_5_11"/>
    <dbReference type="OMA" id="LLPMMTF"/>
    <dbReference type="OrthoDB" id="1384345at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
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        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="325"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="4"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="389" mass="39349" checksum="5DEE7F1F1D3708B5" modified="2010-04-20" version="1">MFRRLLPLAVATFAVTTDSLVIAGLLRPIADTLDVSVSTAGQLVSVFSLTFAIAAPVLGAATANLDRRTVLLLAIGVFVLGNVVAAVGTEFAIVMAARVISALGAALISSIAMATASALAPPDKQGRALALVTAGMTVATTMGVPLGTLIGGADWRITLWAVAGLGTLAGAGIWLGLPKVELPVAPLRDRLKPLGDPGILAILAVTLMILTSGYTLYTYIGVATDAATGGTASGLMAVLIAYGVGSILGNVISGFLTDRYRPVRVLLVGLVMLTAILAITPLVSAAGLFLTMAWATTWGISGWLTGLPQQHRLVTKAPESSAILLGLNASTLHLGIAIGGGIGGLILNWGNTVLLGLMSAAIVAIGLAITLVSTRGRVTEPEPVPASAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXI2</accession>
    <name>D3PXI2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3654"/>
    <dbReference type="EnsemblBacteria" id="ADD43312">
        <property type="protein sequence ID" value="ADD43312"/>
        <property type="gene ID" value="Snas_3654"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3654"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    </dbReference>
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    <dbReference type="OMA" id="IPDYGMV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
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        <property type="entry name" value="CoA-bd"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Succ_CoA_lig_flav_dom"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="795" mass="83097" checksum="3E6E5029D2454D40" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXN9</accession>
    <name>D3PXN9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
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            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3712"/>
    <dbReference type="EnsemblBacteria" id="ADD43369">
        <property type="protein sequence ID" value="ADD43369"/>
        <property type="gene ID" value="Snas_3712"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3712"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_425723_0_0_11"/>
    <dbReference type="OrthoDB" id="642202at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049544" evidence="1">
        <location>
            <begin position="26"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="695" mass="73750" checksum="65856DB47FAC5A43" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXR4</accession>
    <name>D3PXR4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
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            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018965.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3737"/>
    <dbReference type="EnsemblBacteria" id="ADD43394">
        <property type="protein sequence ID" value="ADD43394"/>
        <property type="gene ID" value="Snas_3737"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3737"/>
    <dbReference type="eggNOG" id="ENOG50330PX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_191540_0_0_11"/>
    <dbReference type="OMA" id="CQHQPSC"/>
    <dbReference type="OrthoDB" id="2031580at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046041">
        <property type="entry name" value="DUF5999"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19462">
        <property type="entry name" value="DUF5999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="64" mass="6806" checksum="6A8B8AF0B58A2673" modified="2010-04-20" version="1">MCQHQPSCPEADESDREAARVVASHPEQGWSLLCNGVVVFDDTGELLPDGSVIAPHRPHIGTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXU0</accession>
    <name>D3PXU0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3763"/>
    <dbReference type="EnsemblBacteria" id="ADD43420">
        <property type="protein sequence ID" value="ADD43420"/>
        <property type="gene ID" value="Snas_3763"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3763"/>
    <dbReference type="eggNOG" id="ENOG502ZSC1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032983_0_0_11"/>
    <dbReference type="OMA" id="RMELRTG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="483" mass="51618" checksum="A91927CBB6D4C2A5" modified="2010-04-20" version="1">MDVGISSEQRDKFRRMLAWVVCAAVIAGVGWTGASCLRQQADDPRPMTDAEAQRLSRVNVNNYKAGAVPFTADLPDSAGGGGFDGQIDWSQPVMHAEVAKEGKSTPHTLVQAVPGLVASREGTTRADAPVPEDDWTVRHMGQENRRGDDPQAATVDIIASAVLTLRSGRAADSQILKAKGSWLRQGVIDGATVDVFRAPLLLDAAASDDGQKLPEAVFWVDGESRLRRIQFNPGATSLATVDFLLSKKDVAKVHPVDLLGGAPIDPRKVTKAEAENLAGLRQRNSLGGADADITLPVADGKVIRAKGYVDWRAPMAYLAVDAPGKKNDGLLFVLPSGAATLRTEVDGKPPLQPQANGWKAQAWSERSEDGKPSDIDALLFKVLSMANPQIDNATVVKDKAAWLREDKLGSTATEVYEYPIPGDPDTDEPGQAAFRYWIGSKDDALHRIEMRTRKLGMAHVDLKPTDQPAAVVVPAPVAAGLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXW2</accession>
    <name>D3PXW2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020862.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5661"/>
    <dbReference type="EnsemblBacteria" id="ADD45291">
        <property type="protein sequence ID" value="ADD45291"/>
        <property type="gene ID" value="Snas_5661"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5661"/>
    <dbReference type="eggNOG" id="COG0718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1853989_0_0_11"/>
    <dbReference type="OMA" id="MWADEAA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="138" mass="15043" checksum="05443E085F2C81CE" modified="2010-04-20" version="1">MSEEGPRQAEDWVSQLQLRAAKQLEETQRMQAELEKLSITSTNSDKSVTVSIDASGIMTDLKLTEAVKNSSAADLAAEILAMQHKAQNQLGKAASQVVKDSVGLETATGEAVMNGYRKRFSKKAMEAREEARKKGDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY17</accession>
    <name>D3PY17_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Methionyl-tRNA synthetase</fullName>
            <shortName evidence="9">MetRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">metG</name>
        <name evidence="13" type="ordered locus">Snas_5716</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020917.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5716"/>
    <dbReference type="EnsemblBacteria" id="ADD45346">
        <property type="protein sequence ID" value="ADD45346"/>
        <property type="gene ID" value="Snas_5716"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5716"/>
    <dbReference type="eggNOG" id="COG0143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009710_1_2_11"/>
    <dbReference type="OMA" id="YMRMAGH"/>
    <dbReference type="OrthoDB" id="761140at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00098">
        <property type="entry name" value="Met_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="PTHR45765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="SSF57770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="11">
        <location>
            <begin position="7"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_3" evidence="12">
        <location>
            <begin position="421"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="347"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD45346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="597" mass="66327" checksum="A87126527DF04671" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY95</accession>
    <name>D3PY95_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017033.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1765"/>
    <dbReference type="EnsemblBacteria" id="ADD41462">
        <property type="protein sequence ID" value="ADD41462"/>
        <property type="gene ID" value="Snas_1765"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1765"/>
    <dbReference type="eggNOG" id="ENOG50333S1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_972901_0_0_11"/>
    <dbReference type="OMA" id="ELDWIGG"/>
    <dbReference type="OrthoDB" id="1376561at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="286" mass="30872" checksum="FDD1304559D7430C" modified="2010-04-20" version="1">MSYEDDVSTIKSKAAKIREMAAELWADMGWGIFKSPDDYYGELDWIGGQYKPFYERDPKPLESILTDLEGVKSQLEDPVTEKMDTVKGDLRDWQGTAAEAFVDNYLTPFPKTVTNQVEIVVELHAAIQASKEILDRSRKDAITIADNTIAALNRAMEIEDKNDDGRALTIIGAVLAVAAAIPTAGTSVGAFALGMGMLAGAAGIAAAEVGTRPITGTDPNSILEQMNDQLSSLDSGMTQEEDILAKILHKDADIIDAKMDKILPARPQIADDPGSKEFQLPTNPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYF3</accession>
    <name>D3PYF3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Electron transfer flavoprotein alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1824</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017091.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1824"/>
    <dbReference type="EnsemblBacteria" id="ADD41520">
        <property type="protein sequence ID" value="ADD41520"/>
        <property type="gene ID" value="Snas_1824"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1824"/>
    <dbReference type="eggNOG" id="COG2025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034178_0_1_11"/>
    <dbReference type="OMA" id="DMKENTD"/>
    <dbReference type="OrthoDB" id="1400253at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="4">
        <location>
            <begin position="2"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="315" mass="32071" checksum="DD23DC1A694075D1" modified="2010-04-20" version="1">MILTFVEHDGRRPTAASLTALTVARGLGEPAAVCFTDPADAAPLLAELAAYGAATVHLVDGAGEYSPERWGAALSQLIGDVRPGVVVAPASDRGNEVAAQAAARARLPLATGCVEVAADGTVTRVRGGGILLEDAAVDAGTRMVTVLPTAAEAHQAPRPGEAVPHTFVPDLDGIAATRLVDRAPRGAGVALATAPVVVSGGRGVGSAEGFAPLEELAALIGGAVGCSRVATNNGWRPHSDQVGQTGTKVNPRLYIACGISGATQHWVGCMDSKAILAINTDPDAPMVTRASYAVIGDVHEVLDAVIQEVRRRKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYV7</accession>
    <name>D3PYV7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">def</name>
        <name evidence="3" type="ordered locus">Snas_3885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019111.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3885"/>
    <dbReference type="EnsemblBacteria" id="ADD43540">
        <property type="protein sequence ID" value="ADD43540"/>
        <property type="gene ID" value="Snas_3885"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3885"/>
    <dbReference type="eggNOG" id="COG0242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061901_1_0_11"/>
    <dbReference type="OMA" id="WRERGTS"/>
    <dbReference type="OrthoDB" id="1649129at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="173" mass="18878" checksum="C10F9105A27F0B3D" modified="2010-04-20" version="1">MTETESGTVHDIVYHGTEVLHRRCRTVTDFDDELARLVDDMFASMYAANGVGLAANQIGVDARVFVIDCRDDDGGRLYGHIVNPTLREEPPPRELNVGPEGCLSVPGQYADVARTQTATVDGFDKTGKPITLTSTGEAARCLQHETDHLNGIVYVDKLPKKIRKRLLAEAGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZA2</accession>
    <name>D3PZA2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Catalase-peroxidase</fullName>
            <shortName evidence="8">CP</shortName>
            <ecNumber evidence="8 9">1.11.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Peroxidase/catalase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">katG</name>
        <name evidence="12" type="ordered locus">Snas_1880</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>AH2 + H2O2 = A + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:30275"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="8">Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer or homotetramer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8">Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the peroxidase family. Peroxidase/catalase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.21" evidence="8 9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017147.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1880"/>
    <dbReference type="EnsemblBacteria" id="ADD41576">
        <property type="protein sequence ID" value="ADD41576"/>
        <property type="gene ID" value="Snas_1880"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1880"/>
    <dbReference type="eggNOG" id="COG0376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025424_2_0_11"/>
    <dbReference type="OMA" id="MILAGNC"/>
    <dbReference type="OrthoDB" id="49441at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01961">
        <property type="entry name" value="Catal_peroxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000763">
        <property type="entry name" value="Catalase_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30555">
        <property type="entry name" value="PTHR30555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00460">
        <property type="entry name" value="BPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="SSF48113"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00198">
        <property type="entry name" value="cat_per_HPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 8 9" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 8 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEROXIDASE_4" evidence="11">
        <location>
            <begin position="139"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="cross-link" description="Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-105)" evidence="8">
        <location>
            <begin position="228"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD41576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="741" mass="80348" checksum="4887D3CEDD9E4159" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZD1</accession>
    <name>D3PZD1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017176.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1909"/>
    <dbReference type="EnsemblBacteria" id="ADD41605">
        <property type="protein sequence ID" value="ADD41605"/>
        <property type="gene ID" value="Snas_1909"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1909"/>
    <dbReference type="eggNOG" id="COG0154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_0_4_11"/>
    <dbReference type="OMA" id="TTPEFGW"/>
    <dbReference type="OrthoDB" id="1239251at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="471" mass="50109" checksum="4F668F6E4223BF1E" modified="2010-04-20" version="1">MPANTRTLLTASELVAAYAMREISPVEATQAALDAIEERDGEYNAYCLVDPDAALATARSSEERWLEGNPIGWLDGVPASIKDMFLSEGWPTLRGSRCIDRDQDWNVDSPVTARLREHGLVLLGKTTTPELGWKAVTDSPLEGITRNPWNPELTAGGSSGGSGVAVAAGMGELSVGTDGGGSVRIPASFCGIVGFKPTGSQIPLYPASPFGPLAHAGPMARSVDDVALLLDVLALPDYRDPTSLYPPMAAYREAVRRDVRGLNAAYSPNLGYLSVDPEVAQIVAAAVAKLNDAGLNVEQADPGFADPVEAHEVMWAAGAAKWLDSFPEGSADLVDRGLRKLWDKGLTYSASEYLDALAVRSAIGIRMGEFHTQHDVLITPTVAIPPFKAGHDIPPGSDLSSWQRWAGFSYPFNMTQQPAISVPAGFTSQGLPVGLQIVGPRHSDDLVLAVAKLAEEVCPWPTDKPAAPQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZK2</accession>
    <name>D3PZK2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase U61 LD-carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1980</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S66 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017247.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1980"/>
    <dbReference type="EnsemblBacteria" id="ADD41676">
        <property type="protein sequence ID" value="ADD41676"/>
        <property type="gene ID" value="Snas_1980"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1980"/>
    <dbReference type="eggNOG" id="COG1619">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034346_1_0_11"/>
    <dbReference type="OMA" id="VEYPTTR"/>
    <dbReference type="OrthoDB" id="952832at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027461">
        <property type="entry name" value="Carboxypeptidase_A_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027478">
        <property type="entry name" value="LdcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040449">
        <property type="entry name" value="Peptidase_S66_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040921">
        <property type="entry name" value="Peptidase_S66C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003507">
        <property type="entry name" value="S66_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237">
        <property type="entry name" value="PTHR30237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02016">
        <property type="entry name" value="Peptidase_S66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17676">
        <property type="entry name" value="Peptidase_S66C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141986">
        <property type="entry name" value="SSF141986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S66" evidence="3">
        <location>
            <begin position="16"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S66C" evidence="4">
        <location>
            <begin position="205"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="347" mass="38182" checksum="C2F08B2939149AD4" modified="2010-04-20" version="1">MQIPVYPAKPEPGDRVAVVSPASGLPGILPLPFELGLERLRDVFGLVPVEYPTTRKMGSSPAERAADLHAAFADESIKAIVTSIGGDDQITVLKHLDADVIRANPKPFFGYSDNTNLHAYLSSLGIVSYYGGAVMTEFGRAGALHPITEESLRASLFDSAEFTLRPSPDFTDVNRPWEDPATFDSEPEMFPSEGWIWRNADSVVNGRTWGGCLEIVAWLAMADLAMPPLDYLDGSVLFFETTEELPPDEEVFRILRNLGERGILGRCSALLMGRAKGWSFDKPHDDEQRRQYVDAQREAVIKAMDAYAPGVMTVFNVECGHTDPMSILPYGGQITVDGPAREITVRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q073</accession>
    <name>D3Q073_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5976</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021173.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5976"/>
    <dbReference type="EnsemblBacteria" id="ADD45602">
        <property type="protein sequence ID" value="ADD45602"/>
        <property type="gene ID" value="Snas_5976"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5976"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="YIAWPRV"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="12"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="100"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="170" mass="19880" checksum="C5EADF6725AA23D8" modified="2010-04-20" version="1">MRPEHKTAYREFVAANLDRMCRFAYLTCGDWHRGEDAVQTAFVKLYAAWPRVVRTDRLESYTRRIVTNVLIDQYRRGWFRREKVAEAVPDSPQESDGTDRVAVLRALQRLPVRQRATLVWRYWEDQSVAETARIMRCSENTVKTQTARGLRTLRGLLTESINESFEGSHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0F7</accession>
    <name>D3Q0F7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Urocanate hydratase</fullName>
            <shortName evidence="9">Urocanase</shortName>
            <ecNumber evidence="4 9">4.2.1.49</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Imidazolonepropionate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hutU</name>
        <name evidence="13" type="ordered locus">Snas_0100</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>4-imidazolone-5-propanoate = H2O + trans-urocanate</text>
            <dbReference type="Rhea" id="RHEA:13101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17771"/>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
            <dbReference type="EC" id="4.2.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="9">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the urocanase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.49" evidence="4 9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015392.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0100"/>
    <dbReference type="EnsemblBacteria" id="ADD39821">
        <property type="protein sequence ID" value="ADD39821"/>
        <property type="gene ID" value="Snas_0100"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0100"/>
    <dbReference type="eggNOG" id="COG2987">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018868_0_1_11"/>
    <dbReference type="OMA" id="LVGDWAN"/>
    <dbReference type="OrthoDB" id="100619at2"/>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="hutU"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UROCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="7 9 13" id="KW-0456">Lyase</keyword>
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    <feature type="domain" description="Urocanase_N" evidence="11">
        <location>
            <begin position="7"/>
            <end position="133"/>
        </location>
    </feature>
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        <location>
            <begin position="136"/>
            <end position="343"/>
        </location>
    </feature>
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        <location>
            <begin position="346"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="405"/>
        </location>
    </feature>
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        <location>
            <begin position="48"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
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        <location>
            <position position="126"/>
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        <location>
            <begin position="172"/>
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        </location>
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        <location>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
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        </location>
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        </ligand>
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        <location>
            <begin position="238"/>
            <end position="239"/>
        </location>
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        </ligand>
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            <begin position="259"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="268"/>
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        </location>
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            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
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        </location>
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        </ligand>
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        </location>
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            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00000607"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF17391"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF17392"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ADD39821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="551" mass="59659" checksum="268FE5006727BD35" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0M9</accession>
    <name>D3Q0M9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WGR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2071</name>
    </gene>
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        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="Snas_2071"/>
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        <property type="entry name" value="PQQ_repeat"/>
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    </dbReference>
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        <property type="entry name" value="WGR_domain"/>
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            <end position="77"/>
        </location>
    </feature>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="475" mass="52085" checksum="61F4125BFB04E3EE" modified="2010-04-20" version="1">MTEEHTYLELSEDNGTAHKYYEVTISGTTVTISYGRIGTAGQERVSTFPTLEKARAAAEKKLNEKLRKGYAPAQRGVRQARPVSRRTIVSSRSTAKQAPVLWRFDSGAAAFGIYVDDDRCMVGNQRGDIFKVTHSGEVVGHFSLPDGVKCLVADDFWLYAGCDDGRVYDLSGKIPRVAYEISADVDIFWLDVDDATLGVSDRNGRITAIDHEDEFQWARDVTGNDAWMVRCDADAVYHGHSRGVARYDTGDGTPRWESNVNGNVLFGWQERDSVYAGTGRGEVYRLAKADGAVEARYRCDSAVYSCATSPQGRFVFAGDDESSIYCFDENGERLWKLGTGCGSAFSMQFHGDRLYIVTTSGALACLDASPAAIEAAQAGQLPTATTVKAPPTLAAVAPSVELETVTYDGDGVIVECFRDGAKLRVRAVSDGFEASWNVQFPKDIRQPGARYVVDGLRASERGGFYRSYGEIRRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Q8</accession>
    <name>D3Q0Q8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2100"/>
    <dbReference type="EnsemblBacteria" id="ADD41794">
        <property type="protein sequence ID" value="ADD41794"/>
        <property type="gene ID" value="Snas_2100"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2100"/>
    <dbReference type="eggNOG" id="ENOG502ZBDW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083369_1_1_11"/>
    <dbReference type="OMA" id="YFSGEQD"/>
    <dbReference type="OrthoDB" id="1394285at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025649">
        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="entry name" value="PTHR38847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048142" evidence="1">
        <location>
            <begin position="31"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="23807" checksum="FF4A9D8FF10AE498" modified="2010-04-20" version="1">MYARKRIPVLTGLIAATALALTALSSPAQASSFQDDDPPTEQITIKVATVNGSGCAPGTAAVSVSPDNTAFTVTYSEYLAQAGGNSDPTDFRKNCQLNLEVHVPQGFTYAIATADYRGFAHLEPGATGMQQALYYFQGMSETHTSKHQLSAPASDNWQYTDETDVDQLVYKPCGEERNFNINTELRVGAGDDPAKKSFVAMDSTDGAINTIFNFSWKKCPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q139</accession>
    <name>D3Q139_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Crotonyl-CoA reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019360.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4138"/>
    <dbReference type="EnsemblBacteria" id="ADD43789">
        <property type="protein sequence ID" value="ADD43789"/>
        <property type="gene ID" value="Snas_4138"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4138"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_5_0_11"/>
    <dbReference type="OMA" id="HEAWQAN"/>
    <dbReference type="OrthoDB" id="884088at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043880">
        <property type="term" value="F:crotonyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010085">
        <property type="entry name" value="Crot_CoA_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01751">
        <property type="entry name" value="crot-CoA-red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="2">
        <location>
            <begin position="51"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="443" mass="48585" checksum="EC7117373F7E5194" modified="2010-04-20" version="1">MKTILDAIQSPESTPDDFAALPVPEEYRAVTLRANETDMFAGMDSADKDPRRSLHTEHVPTPSLEPGEALVAVMASAVNYNTVWSAIFEPIPTFDFLRRYGRTSPAAKRHDQPYHVVGSDLSGVVLRVGPGVNAWRPGDHVVAHCLSVELEAAAGHNDTMLDPEQRIWGFETNFGGLAELAVVKANQLMPKPDHLTWEESACVGLVNSTVYRQLVSLNGAGMKLGDNVLIWGASGGLGSYAVQYALASGATPVCVVSSPEKAELCRSMGAEAIIDRNAEGYRFWQDAHTQDPKEWKRFGARIRELTGGEDVDIVFEHPGRETFGASVFVTRRGGTIVTCASTSGHVHEYDNRYLWMSVKRIIGSHFANYAEAWAANRLVSKAKIHPTLSKVYPLEQTGQAAHDVHTNSHHGKIGVLCLSPREGLGVRDEATRQRHLNAINRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q154</accession>
    <name>D3Q154_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019375.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4153"/>
    <dbReference type="EnsemblBacteria" id="ADD43804">
        <property type="protein sequence ID" value="ADD43804"/>
        <property type="gene ID" value="Snas_4153"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4153"/>
    <dbReference type="eggNOG" id="COG4587">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084465_0_1_11"/>
    <dbReference type="OMA" id="YLIDFPA"/>
    <dbReference type="OrthoDB" id="1552415at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010390">
        <property type="entry name" value="DUF990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06182">
        <property type="entry name" value="ABC2_membrane_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="265" mass="29160" checksum="B274B185671954BF" modified="2010-04-20" version="1">MRMTLALARAGFRRYSTYRQATAASILTNSMFGFLRVYVLFAAVAAAGGVAGGYTREQLSTYTWVTQGMIGVVALWGWNELADKVRTGEVVGDLLRPVNPIWTYFATDLGRAGFASCTRLLAPIVVGALVFPFYWPRHPASYPLFLVSVLLAVSVCFALRYLVNLSAFWLLDSRGITAVWTLVSGLGAGLYFPMSFLPGWLAFVMQYLTPFPSIMQFPADVLVERDGFGGQFTRLAVQALWALICLAIVFAVQRRAVRKLVVQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1D6</accession>
    <name>D3Q1D6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TAP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6092</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021287.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6092"/>
    <dbReference type="EnsemblBacteria" id="ADD45716">
        <property type="protein sequence ID" value="ADD45716"/>
        <property type="gene ID" value="Snas_6092"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6092"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_3_3_11"/>
    <dbReference type="OrthoDB" id="665798at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048156" evidence="1">
        <location>
            <begin position="27"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="102"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="478" mass="52661" checksum="1DA71CCE0C51D644" modified="2010-04-20" version="1">MRKRYVALAAVLAVATAVTVTRTVSADPVADIAWGPCEGVKDDVQCATLEVPVDYANPDGEAITVGLSKRAATDPDKRIGSLLVDGVDMVKDAPVGSKRMQERFDLIGFDPRGTKRSTRIECDKADMAAVTKIGVPNDRKEFKALVKANRSLAEGCRDLTGPLFDHADNLHIVEDIESIRKALGEKKFNFLGFSNGTLMGQQYAEKYPKNLRSMVLDGNMDHSLESTWEYMSSETAAVERNFNSFAKWCDETKDCALYGEGTADVYGELRDAARAGELTDPETGAPIDFYDFSDRAFAVNTPQQWSVLAKDLKTLRAGEDELKLDDQPRELPVEYLMQSKFCGNWDLGVRNFGEWEELTERLAEEYPNTQWSKFAGFQSACFGGAIETTNPQAPLEIDGAPPLVMIGNHNDFATVYEWSKTAAEQSGATLITYEGYGHTVYGGGNKCVDEPVESYFIELKQPDEGISCESTDEPGRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1N4</accession>
    <name>D3Q1N4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
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        <property type="protein sequence ID" value="ADD39882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-KW"/>
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            <end position="72"/>
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            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="161" mass="17533" checksum="8D4881BC5EB2474D" modified="2010-04-20" version="1">MRTRIIKATAVFVTGLLAGMFTYGALNVAQAFKAVPLDVRFTYHVALMNVNAYVMQITMGLAVLSALTLTVIARGTPRLLAGAATVLGVATFVITRFGNVPINQQIRQWVKTSPPADVASILDRWELLHYFRTGTAVLMFATIVLIAVRYRALRPADPATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1W4</accession>
    <name>D3Q1W4_STANL</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2137"/>
    <dbReference type="EnsemblBacteria" id="ADD41831">
        <property type="protein sequence ID" value="ADD41831"/>
        <property type="gene ID" value="Snas_2137"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2137"/>
    <dbReference type="HOGENOM" id="CLU_439982_0_0_11"/>
    <dbReference type="OMA" id="VYMASAD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="621" mass="64786" checksum="E3017AB084231314" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q247</accession>
    <name>D3Q247_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017485.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41914">
        <property type="protein sequence ID" value="ADD41914"/>
        <property type="gene ID" value="Snas_2224"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2224"/>
    <dbReference type="eggNOG" id="ENOG502ZC20">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1320305_0_0_11"/>
    <dbReference type="OMA" id="KAWMEAN"/>
    <dbReference type="OrthoDB" id="1775327at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021315">
        <property type="entry name" value="Gap/Sap"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11139">
        <property type="entry name" value="SfLAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ADD41914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="210" mass="21970" checksum="8F5558444FD4C74A" modified="2010-04-20" version="1">MNLQVLPLAVTMMVGPQIMAATVFVMNARAIRVSAAFLAGVALATTAGVVVARGLASVLGGVVLSGGGSLSAGWVGVLVQLGLVVLLLVLALVSFLGRGDARPPRWLEALMSATPSMALRTGLMVILTMPSDIVIMLTVGVNLDHHGETVLAAVPFIVATVLVASLPLGFYLVLRDRAERVMPRVRDWLNVNSWVVNVGVCLFFAALVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q253</accession>
    <name>D3Q253_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
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            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017491.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2230"/>
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        <property type="protein sequence ID" value="ADD41920"/>
        <property type="gene ID" value="Snas_2230"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2230"/>
    <dbReference type="eggNOG" id="COG4805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018914_3_0_11"/>
    <dbReference type="OMA" id="SEIWRAI"/>
    <dbReference type="OrthoDB" id="520320at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="560" mass="63080" checksum="6C0F619FDD7B52E2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q268</accession>
    <name>D3Q268_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017506.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2245"/>
    <dbReference type="MEROPS" id="S54.029"/>
    <dbReference type="EnsemblBacteria" id="ADD41935">
        <property type="protein sequence ID" value="ADD41935"/>
        <property type="gene ID" value="Snas_2245"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2245"/>
    <dbReference type="eggNOG" id="COG0705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067823_2_0_11"/>
    <dbReference type="OMA" id="WAHLMAN"/>
    <dbReference type="OrthoDB" id="2053476at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="65"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="208" mass="22593" checksum="015A86081E5457C2" modified="2010-04-20" version="1">MSFTSTPQSTPKVSTKWLNVKVAAILTGLFVALIWVLEALDYALPIDLDQWGIRSWSITGIFPGFIMAPVLHADFDHLIGNTVPVMVLGFLAAMRGLRHFFTATALIILIGGLGVWLLSSPGVLTVGASGMIFGYFGYLVGRGILSRRGWDIVIAVAVIILYGSIIWGIFPSDPFISWQGHLFGFIGGLAAAWILRKKYRKPADEVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q282</accession>
    <name>D3Q282_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative PAS/PAC sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019386.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4164"/>
    <dbReference type="EnsemblBacteria" id="ADD43815">
        <property type="protein sequence ID" value="ADD43815"/>
        <property type="gene ID" value="Snas_4164"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4164"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_43_3_11"/>
    <dbReference type="OMA" id="YHADHPA"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="13"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="688" mass="75040" checksum="E6100E203E8A65DB" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2C6</accession>
    <name>D3Q2C6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019430.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4210"/>
    <dbReference type="EnsemblBacteria" id="ADD43859">
        <property type="protein sequence ID" value="ADD43859"/>
        <property type="gene ID" value="Snas_4210"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4210"/>
    <dbReference type="eggNOG" id="ENOG5032Y78">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_961956_0_0_11"/>
    <dbReference type="OMA" id="PRLWPEI"/>
    <dbReference type="OrthoDB" id="1789455at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="252" mass="27176" checksum="8C69DE482E317398" modified="2010-04-20" version="1">MNAVAFAAPEARIALSIDLARVIREYSDSRPRSRQVNIGPSEIGVECLRRLGYKALGYAASNGGGDPLPPFIGTAVHAELAAAFEADNERLGRVRWLVEHRVTVRGSIRGTLDLYDHDTRTVIDHKIVGPSTLQKTRAGGPSEQYRAQVHLYGYGLSAEMPVERVAIAYFPRAGHLDGRIIWAEPFDPAVAETALDRLASVIHLAGVLQVDDHPDRWAHVPATPGPGCAFCPFFNAQGVTDADTASCPGTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2K5</accession>
    <name>D3Q2K5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sortase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021327.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6133"/>
    <dbReference type="EnsemblBacteria" id="ADD45756">
        <property type="protein sequence ID" value="ADD45756"/>
        <property type="gene ID" value="Snas_6133"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6133"/>
    <dbReference type="eggNOG" id="COG3764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045680_5_1_11"/>
    <dbReference type="OMA" id="WTNVRAH"/>
    <dbReference type="OrthoDB" id="1022681at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05830">
        <property type="entry name" value="Sortase_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042003">
        <property type="entry name" value="Sortase_E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
        <property type="entry name" value="Sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01076">
        <property type="entry name" value="sortase_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="312" mass="34508" checksum="6022ECE3F1C80372" modified="2010-04-20" version="1">MHRGDDDWFGEAEPPFDPPARGRASVPGQGGRVPPPEVPDEPETGEPEIDPLGLIPGPDETTLIPRIPRESAPPPAADRPETRRRRSIKRHRDGSPSPQAKAVRIGGELLLTLGVVVMLFVAYQMWGTEAEINNAQGKQSDAWEDQVDKGKDPTLDPVPGGAIARLYMPQIRSEPWVIVEGTDLDDIEKAPGHYSDSAMPGEKGNFAVAGHNVSAIFRHIDELKEGDKVVIETAKKFFIYEITGNKIVKPTNLDVVAPVPNEPGVKPTDEDRWFTMTTCYPWWDNYERYIVWAQLTDERKRGDALPPEAGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q349</accession>
    <name>D3Q349_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0301"/>
    <dbReference type="EnsemblBacteria" id="ADD40019">
        <property type="protein sequence ID" value="ADD40019"/>
        <property type="gene ID" value="Snas_0301"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0301"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1142044_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="30"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="243" mass="26824" checksum="AE2E86B71DB17B69" modified="2010-04-20" version="1">MAAAYKHRPPYPTEVFDTLQELIVDEPRAVLDIGAGEGAIARPLATRVDRIDAVDVSAAMIAAGRQRPGGQAANIRWIHSDVESATLDGPYALVTAGASLHWMRWPDTMNRLVPLLSPNAKLAIVDHGPRDLPWQDELLAIIKRHSRNPDYDPSFSIVDFLVGQGLLDDIDKAEFGPTPFWQPVADYVEQFHSTATLAREHMSPREVREFDEAVEAAVSPWITDGRVKLPIVAKVVWGRPQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Q0</accession>
    <name>D3Q3Q0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019538.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4320"/>
    <dbReference type="EnsemblBacteria" id="ADD43967">
        <property type="protein sequence ID" value="ADD43967"/>
        <property type="gene ID" value="Snas_4320"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4320"/>
    <dbReference type="HOGENOM" id="CLU_148707_0_0_11"/>
    <dbReference type="OrthoDB" id="1893188at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="145" mass="16077" checksum="28955D781224E82C" modified="2010-04-20" version="1">MCSDVVAGDLNDLRIAALNLGKMSELYTNGAFVLGIAQGADTETYGRPHEWWSYVEQQLATALRFTYDRLNDGQEALLAAIDAYAYVDGDNAKGLTDVGKEYKEYISNPNNVGDEKYYDPPPLHTMVDAPDLGDKPEGWEEKYDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3R7</accession>
    <name>D3Q3R7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4337</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019555.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4337"/>
    <dbReference type="EnsemblBacteria" id="ADD43984">
        <property type="protein sequence ID" value="ADD43984"/>
        <property type="gene ID" value="Snas_4337"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4337"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_3_1_11"/>
    <dbReference type="OMA" id="GDEMSGP"/>
    <dbReference type="OrthoDB" id="1863483at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="349"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="467" mass="46775" checksum="810837F71F22AA10" modified="2010-04-20" version="1">MRLPTRYITGSFLARFAEEGMGVTMALLALQRTGSVGQAAALSAAWLAPHVLAAPLIGTLASRARHPTRFYAIGLLIVAATIAAATLLLGRVPLLAVCAIAAVGGCCGPVVSGGLSSLVAELLPEGHRERAYSWDSATYNAASIAGTAVATAVAATLGGEWSGWMLATSATLAAVLIALLPASRTPLGSAADATSPAARHDDARVPSQLAEPPRPAEPTAVLASESSQLVEPPLPREREASGGRPSELAGPPQPSEPTTVPPAVKPSLVADMAAGLKALWRDKTLRAVTAATCLAYLGLGGLTITAVIAARQWGDGDFGGALVTAFAVGALAGALALTKWTPPISPQRLAAYSLLVTGVSLALAAAAPNLVVCLVLFAVAGDGPLLSATLQVRAAHAPPGVRAQVFTTGAALKLSAAAIGTALAGALESLPAALPLALIAATQLGACALVWTLAPAPTREPMPSRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q470</accession>
    <name>D3Q470_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6338"/>
    <dbReference type="EnsemblBacteria" id="ADD45955">
        <property type="protein sequence ID" value="ADD45955"/>
        <property type="gene ID" value="Snas_6338"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6338"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_81_13_11"/>
    <dbReference type="OMA" id="TPYSYLM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="145" mass="16212" checksum="21449C957EDA4A21" modified="2010-04-20" version="1">MWDGWFVILEDLVRLRRARDTMDREYDKPLDVPALARVALMSPGHFSRSFRAAYGETPYSYLMTRRIERAKALLRKGDLSVTEVCFAVGCTSLGSFSSRFTELVGESPSAYRARDHADAAAIPPCVAKVYTRPVRNGEAKPPGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4E6</accession>
    <name>D3Q4E6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sodium/proline symporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Proline permease</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_0389</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the sodium-dependent uptake of extracellular L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-proline(in) + Na(+)(in) = L-proline(out) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:28967"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015677.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0389"/>
    <dbReference type="EnsemblBacteria" id="ADD40106">
        <property type="protein sequence ID" value="ADD40106"/>
        <property type="gene ID" value="Snas_0389"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0389"/>
    <dbReference type="eggNOG" id="COG0591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018808_15_2_11"/>
    <dbReference type="OMA" id="CWTDLIQ"/>
    <dbReference type="OrthoDB" id="231452at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005298">
        <property type="term" value="F:proline:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031402">
        <property type="term" value="F:sodium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015824">
        <property type="term" value="P:proline transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11475">
        <property type="entry name" value="SLC5sbd_PutP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011851">
        <property type="entry name" value="Na/Pro_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018212">
        <property type="entry name" value="Na/solute_symporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02121">
        <property type="entry name" value="Na_Pro_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00456">
        <property type="entry name" value="NA_SOLUT_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00457">
        <property type="entry name" value="NA_SOLUT_SYMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="8" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="409"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="471"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="513" mass="54977" checksum="94D27D6E625545E5" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4X0</accession>
    <name>D3Q4X0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2467</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017721.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2467"/>
    <dbReference type="EnsemblBacteria" id="ADD42150">
        <property type="protein sequence ID" value="ADD42150"/>
        <property type="gene ID" value="Snas_2467"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2467"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="RWIHLIL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="210"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="409" mass="43887" checksum="B565E508E06E980F" modified="2010-04-20" version="1">MTVFRPLTSLSTYRGWMWLVLGGAMLMPYMMAAEVMRMLVIGESDFGSTLITAQLPAFVAMLPVIAVTALVLPVRLLSAIPARSLLGVAIPVAASIRDWDRRARDAAWFTLHLGLGGLVSGITLAVIPFAGFITVLPLVSSRNELIGKYFTVHWEAWWGLVLGPLMLLALVYLAWFTTWLVRWLAPRLLGATAAEKLAETRARAANLAARNRIARELHDSVGHALSVVTVQSAAAGRVIDSNPEFARRAMSSIEETARRALEELDTVLGILREDGPADTEPARGLDALSALVASSGIDASVEVDADLAALPPLVSREGYRIVQESLTNALRYGPDRTATVRITTTHNGLRVRVTNPIAPSAAPPREGRGIIGMRERVTVLGGTLSAGPRDGRWVVTAELPIGQADAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q544</accession>
    <name>D3Q544_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribonuclease II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4448</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019664.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4448"/>
    <dbReference type="EnsemblBacteria" id="ADD44093">
        <property type="protein sequence ID" value="ADD44093"/>
        <property type="gene ID" value="Snas_4448"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4448"/>
    <dbReference type="eggNOG" id="COG0557">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020724_0_0_11"/>
    <dbReference type="OMA" id="QAPPEWE"/>
    <dbReference type="OrthoDB" id="1602988at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DRBM" evidence="3">
        <location>
            <begin position="535"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="510"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="617" mass="67139" checksum="1EF4B6BD40D37D5D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q592</accession>
    <name>D3Q592_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019712.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4496"/>
    <dbReference type="EnsemblBacteria" id="ADD44141">
        <property type="protein sequence ID" value="ADD44141"/>
        <property type="gene ID" value="Snas_4496"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4496"/>
    <dbReference type="eggNOG" id="COG1981">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114403_0_0_11"/>
    <dbReference type="OMA" id="KFWLTLA"/>
    <dbReference type="OrthoDB" id="1656455at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="183" mass="19779" checksum="BC97D4C23D852855" modified="2010-04-20" version="1">MTTAPVRTLPKPLRRGLLTLHVITSVGWLGISLGNIALALTVYNTSDPALQHSIYRVLEIVGNIVILPISLTAFATGVVLSVGTHWGLLRHKWVLIKLVLTLGTVLMTYLSLVPGLRESAAIVDATAPDRLADIDGSGLLSAAFVSSSIYTFNVVLSTFKPWGRTRWGRRAAEQARTRVAARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5H4</accession>
    <name>D3Q5H4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021605.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6418"/>
    <dbReference type="EnsemblBacteria" id="ADD46034">
        <property type="protein sequence ID" value="ADD46034"/>
        <property type="gene ID" value="Snas_6418"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6418"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_3_2_11"/>
    <dbReference type="OMA" id="GVWAYFA"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="22"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD46034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="124" mass="13600" checksum="171D12FAA93ECD4A" modified="2010-04-20" version="1">MTVVRVIADATTPASPVAGDPIPRKDAERIAGVLKALADPNRLRLISLIQSQDGGEACVCELTEPLGLSQPTISHHLRILTEAGLVERDKRGVWAYFRVLPETLNAVAELLTPPKRRGRRRHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5H7</accession>
    <name>D3Q5H7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021608.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6421"/>
    <dbReference type="EnsemblBacteria" id="ADD46037">
        <property type="protein sequence ID" value="ADD46037"/>
        <property type="gene ID" value="Snas_6421"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6421"/>
    <dbReference type="eggNOG" id="ENOG5033CTS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1142047_0_0_11"/>
    <dbReference type="OMA" id="ALPSWYE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD46037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="243" mass="25162" checksum="D4D34CA588D5D7D2" modified="2010-04-20" version="1">MSTHFEVPGQRDRPTSVSVAVYAQFAVGALGVIATVIGVIQTADMMGRVEKAITDTGSVNSADVDTVIGFASAVSYALIFASLLFALAVAIMGIFNLKGKNGARITTWVLAGLGLLCGVCGSISGAANSLGGNSSTANDELTKAMERALGDVPAWYNISNLAVTVLDVILYLAIIILLAIPASNDFFRKPKNNVDVMLPPEAYMDAPPPPPAPGTQPPPPPAAPEAQPPQQPRPDDDPGTPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5V1</accession>
    <name>D3Q5V1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0536</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0536"/>
    <dbReference type="EnsemblBacteria" id="ADD40250">
        <property type="protein sequence ID" value="ADD40250"/>
        <property type="gene ID" value="Snas_0536"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0536"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="ECARADE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="137"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="204" mass="22007" checksum="CE065D981123533D" modified="2010-04-20" version="1">MIEILYGHENTLWSESLASVLSRESDIKVVGEANRPDEILGLAMDSPPDVVVLALYLTEVSVVGELCHKLSEGPGQHRVLVLHERDMPLAPFAEAFRSSPKVSFMGTCASAAQFLESVRQIACGHLVMDSDVALGLLRANHSPLTAREREVLSITHGGATPKEIASKLQLSVGTVRNYLANACAKLGARNRIEAIRVAQSAGWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5V3</accession>
    <name>D3Q5V3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0538</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0538"/>
    <dbReference type="EnsemblBacteria" id="ADD40252">
        <property type="protein sequence ID" value="ADD40252"/>
        <property type="gene ID" value="Snas_0538"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0538"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_0_11"/>
    <dbReference type="OMA" id="SAVMFEH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="15"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="410"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="496" mass="53085" checksum="48A5E00314C237B5" modified="2010-04-20" version="1">MGTPVYPQTLLDALRREPESPAFEHGARVVARGELLDVIAGYVAGLRAAGVGPGKGVAIATATTAEGFAAQIAAHVVGSRVVGVLPDLPSGHLRHIFDDVEYLLVDAETGTPDLLGAAKGCQVLTVGADLAGDGGSLVPQGRRETIAYITFTSGSTGSPRGIAFTYAAMSGNWSLQPEVWGSRTEELAETHNRFLLYGSLSSAIVFEQLGLTLLSGGTAVIPEGPVEFPDVIERLGITMCLLSVPRYHRVLDALRDKEVDISSLRCAIVAGSPVSPRRLAEGFERLGPVLRQTYGQTEDGTLTMLTKDDVDQWPEALSSVGRVWENVQLEIRDAVGRAVPPGRSGEVWVRTPGQLCGYWDDEEETVEVLRDGWVRTRDLGYLSGDGFVFLTGRSRDIIIVNAVLHYAGPIERALMEHPDVDQAFVVGTPDEDAGEAIHAIILPVKESHPEPQELRELVTRELGASAAPGHLHFVTEIPVAPGGKPDKRALLARVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q604</accession>
    <name>D3Q604_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015874.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0589"/>
    <dbReference type="EnsemblBacteria" id="ADD40303">
        <property type="protein sequence ID" value="ADD40303"/>
        <property type="gene ID" value="Snas_0589"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0589"/>
    <dbReference type="eggNOG" id="ENOG5033BNY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158406_1_0_11"/>
    <dbReference type="OMA" id="NWRDEMA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025323">
        <property type="entry name" value="DUF4229"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14012">
        <property type="entry name" value="DUF4229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="82" mass="9150" checksum="F3C1256A3679CFF5" modified="2010-04-20" version="1">MSPLWKFTLGRVGLCVLIGALLWPTGLHILVIAMAALLGSFLLSFVVLKKWRTEMLADVDEAVKRRRAQKEELRSALAGEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q614</accession>
    <name>D3Q614_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015884.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0599"/>
    <dbReference type="EnsemblBacteria" id="ADD40313">
        <property type="protein sequence ID" value="ADD40313"/>
        <property type="gene ID" value="Snas_0599"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0599"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_20_1_11"/>
    <dbReference type="OMA" id="MYIGYVG"/>
    <dbReference type="OrthoDB" id="867226at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="6"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="488" mass="52662" checksum="471E6595550E6E32" modified="2010-04-20" version="1">MDAIEHDVVIAGGGPTGLMLAGELALAGVDVAVVERRVGQELPESRAGGLHSRTIEVLDQRGIADRFLSRGKRSRAVGFATSQVDIGDLPTRHGYLLGLWQNHTEHELAGWVGELDVPVYRGREVIGFAQDDSGVDIEVSDGGPMRARYLVGCDGGRSLVRKTAGIDFPGWDPTFSCLVAEVEVERVPDWLSRQPVGPARRRAGSGKGTPVRIVVAESRVGRTGEASLHDLSEALIAEYGTDYGVSNPSWISRFGDTSRQAASYRDRRVLLAGDAAHVHAPVSGQGLNLGVQDAVNLGWKLAQVVAGASAESLLDTYHAERHPVAARVLRHTMAQHALLRTDERTRSLRDIMSELLSLYEPRQRVAAMIAGLDIRYDCGEGHPLLGRRMPDLDLVTADGPRRVFTLLHQARPVLLNLGEPNGFDVTPWAGRIRSVDAKAAATWELPLLGEVAAPAALVIRPDGYVAWAGELTDASLPDALTSWFGEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q625</accession>
    <name>D3Q625_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2518</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017771.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2518"/>
    <dbReference type="EnsemblBacteria" id="ADD42200">
        <property type="protein sequence ID" value="ADD42200"/>
        <property type="gene ID" value="Snas_2518"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2518"/>
    <dbReference type="HOGENOM" id="CLU_2169524_0_0_11"/>
    <dbReference type="OrthoDB" id="1703187at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="110" mass="12111" checksum="00B71EF2AD40BCA6" modified="2010-04-20" version="1">MKAEITNLVRELTESGVRLDPDDPRFDAKRAREVLAVEGVDVPTVDGLVWVSVNADGTLAALDVDTDTLRRDEREIAANITAAIKQAERIIDEALTIVRARQRKDGRGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6E6</accession>
    <name>D3Q6E6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional repressor, CopY family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4544"/>
    <dbReference type="EnsemblBacteria" id="ADD44189">
        <property type="protein sequence ID" value="ADD44189"/>
        <property type="gene ID" value="Snas_4544"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4544"/>
    <dbReference type="eggNOG" id="COG3682">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119090_1_0_11"/>
    <dbReference type="OMA" id="MDHLWST"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="125" mass="13815" checksum="B128816C7166D1FF" modified="2010-04-20" version="1">MARLGELEHAIMEVLWSDPEPQTARQVRDALTDRDLAATTILTVLSRLEAKGLVTRDRSSRAHRYQPTDAREVHVAALMRQALDSAPDADAALARFADAVTAEEAQALTEALDEAMRRRHKEGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6I1</accession>
    <name>D3Q6I1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019795.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4580"/>
    <dbReference type="EnsemblBacteria" id="ADD44224">
        <property type="protein sequence ID" value="ADD44224"/>
        <property type="gene ID" value="Snas_4580"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4580"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089258_4_0_11"/>
    <dbReference type="OMA" id="MHPYELG"/>
    <dbReference type="OrthoDB" id="1706427at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="15"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="23211" checksum="41628E84A780A78D" modified="2010-04-20" version="1">MAKKRKVGNPLALAVLSYLLMKPMHPYELGRTLKKHGDDRNIKYNHGSLYMVVRQLHAAGFIAEQEIERQGNLPERTVYAITADGRQELRDWLRELIAEPKHEYPAFVTGLSLISALPPQEATELLRKRLEQLAVQREDIQSVLDSAASQGVPGLFLVEEDYRLAIVDTEVDFVEKFLHDINDPETDWAGPWGEFHEQHTEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6W3</accession>
    <name>D3Q6W3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015933.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0649"/>
    <dbReference type="EnsemblBacteria" id="ADD40362">
        <property type="protein sequence ID" value="ADD40362"/>
        <property type="gene ID" value="Snas_0649"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0649"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_0_3_11"/>
    <dbReference type="OMA" id="WNESFDR"/>
    <dbReference type="OrthoDB" id="1617768at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="117" mass="13384" checksum="BF0C7368FDE55D6D" modified="2010-04-20" version="1">MARAATTTDAFNAVAEPRRREILAILAEGERTVTELVDALGLVQPLVSKHLRVLREVGLVSVREEGRRRVYSMDGRPLKAVHDWVKGFEQTWNRRFDLLDGVLEELKTEEEGNEDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q718</accession>
    <name>D3Q718_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0704"/>
    <dbReference type="EnsemblBacteria" id="ADD40417">
        <property type="protein sequence ID" value="ADD40417"/>
        <property type="gene ID" value="Snas_0704"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0704"/>
    <dbReference type="eggNOG" id="ENOG5032Y97">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2304300_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021465">
        <property type="entry name" value="DUF3117"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11314">
        <property type="entry name" value="DUF3117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="100" mass="10503" checksum="2D5C15EA317E4AC3" modified="2010-04-20" version="1">MAAMKPRTGDGPLEVTKEGRGIVMRVPLEGGGRLVVEMTPDEAETLSQELKNLNGLPESPIETHPSCGPGGGRGVVRGRDLSTVRTRAVPTSIEAGGTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q728</accession>
    <name>D3Q728_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA/rRNA methyltransferase (SpoU)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015998.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0715"/>
    <dbReference type="EnsemblBacteria" id="ADD40427">
        <property type="protein sequence ID" value="ADD40427"/>
        <property type="gene ID" value="Snas_0715"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0715"/>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085947_0_0_11"/>
    <dbReference type="OMA" id="TDRYQHV"/>
    <dbReference type="OrthoDB" id="1422015at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="1">
        <location>
            <begin position="58"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="205" mass="23159" checksum="9EED937B5270F6A3" modified="2010-04-20" version="1">MNDSDEVGVGPWSGPWPEDDRYDPELLAEGDRRNVVDRYRYWRREAIVADLDEHRHDFHVAIENWQHDFNIGTVVRNANAFAAKAVHIVGKRRWNRRGAMVTDRYQHVHHHDTIDGFVDWAQRHELPIIGIDNLPGSVPLETTTLPSACVLFFGQEGPGLSRAARDASRLVCSIAQFGSTRSINAGVASGIAMHAWIRDHAVIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q785</accession>
    <name>D3Q785_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2679</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017927.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2679"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42356">
        <property type="protein sequence ID" value="ADD42356"/>
        <property type="gene ID" value="Snas_2679"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2679"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015079_0_0_11"/>
    <dbReference type="OrthoDB" id="635734at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="5">
        <location>
            <begin position="13"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="4">
        <location>
            <begin position="206"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="678" mass="75652" checksum="4E7EF1CAC9E50349" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7C7</accession>
    <name>D3Q7C7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Assimilatory sulfite reductase (ferredoxin)</fullName>
            <ecNumber evidence="5">1.8.7.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ordered locus">Snas_2722</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3 H2O + hydrogen sulfide + 6 oxidized [2Fe-2S]-[ferredoxin] = 7 H(+) + 6 reduced [2Fe-2S]-[ferredoxin] + sulfite</text>
            <dbReference type="Rhea" id="RHEA:23132"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="EC" id="1.8.7.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nitrogen metabolism; nitrate reduction (assimilation).</text>
    </comment>
    <dbReference type="EC" id="1.8.7.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017969.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2722"/>
    <dbReference type="EnsemblBacteria" id="ADD42398">
        <property type="protein sequence ID" value="ADD42398"/>
        <property type="gene ID" value="Snas_2722"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2722"/>
    <dbReference type="eggNOG" id="COG1251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003291_0_0_11"/>
    <dbReference type="OMA" id="FAQVDPW"/>
    <dbReference type="OrthoDB" id="1128731at2"/>
    <dbReference type="UniPathway" id="UPA00653"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008942">
        <property type="term" value="F:nitrite reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050311">
        <property type="term" value="F:sulfite reductase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012744">
        <property type="entry name" value="Nitri_red_NirB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017121">
        <property type="entry name" value="Nitrite_Rdtase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041575">
        <property type="entry name" value="Rubredoxin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18267">
        <property type="entry name" value="Rubredoxin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037149">
        <property type="entry name" value="NirB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02374">
        <property type="entry name" value="nitri_red_nirB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 12" id="KW-0274">FAD</keyword>
    <keyword evidence="7 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 12" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0883">Thioether bond</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="17">
        <location>
            <begin position="2"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin_C" evidence="18">
        <location>
            <begin position="329"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Fer2_BFD" evidence="16">
        <location>
            <begin position="419"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR_ferr" evidence="15">
        <location>
            <begin position="551"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="14">
        <location>
            <begin position="623"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR037149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF18267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ADD42398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="834" mass="88474" checksum="807D5FC8DED32F5E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Z6</accession>
    <name>D3Q7Z6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016072.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0789"/>
    <dbReference type="EnsemblBacteria" id="ADD40501">
        <property type="protein sequence ID" value="ADD40501"/>
        <property type="gene ID" value="Snas_0789"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0789"/>
    <dbReference type="HOGENOM" id="CLU_1936842_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049638" evidence="1">
        <location>
            <begin position="30"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="130" mass="13939" checksum="649A94FA57F78579" modified="2010-04-20" version="1">MKTFRNKALLGVAVVAAIAAGTIGFTANADSVEAKATPIHTKDGHGSITFYKSTDNFVVKDHKKDGRGVRAIYTIGGQGSDYMYNTKGANTSAKYNRNFQEGTKLKIQICLTKNGTPIGSTCSDWKSRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8G3</accession>
    <name>D3Q8G3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2862</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2862"/>
    <dbReference type="EnsemblBacteria" id="ADD42537">
        <property type="protein sequence ID" value="ADD42537"/>
        <property type="gene ID" value="Snas_2862"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2862"/>
    <dbReference type="eggNOG" id="COG1764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105860_1_0_11"/>
    <dbReference type="OMA" id="ECFIANS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="183" mass="20062" checksum="A089759AE39D71D6" modified="2010-04-20" version="1">MAETHHYDVTVEWTGNLGTGTSDYRAFSRDHELLGSGKAPIAASSDPAFRGDASRWNPEELLVASVAQCHMLWYLHLCATNGVTVVEYEDRAAGVMTMDASGGGGQITEITLRPQVTVTDASMLPLARELHGEVHKVCFIARSVNFPIRHEPDIQNVKLAEVGTYMGYRLSARANNLGAWPKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8K9</accession>
    <name>D3Q8K9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 3">Acyl carrier protein</fullName>
            <shortName evidence="1">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">acpP</name>
        <name evidence="5" type="ordered locus">Snas_4810</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="PTM">
        <text evidence="3">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020022.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4810"/>
    <dbReference type="EnsemblBacteria" id="ADD44451">
        <property type="protein sequence ID" value="ADD44451"/>
        <property type="gene ID" value="Snas_4810"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4810"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108696_5_6_11"/>
    <dbReference type="OMA" id="CEIPDEQ"/>
    <dbReference type="OrthoDB" id="1943389at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 2 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="6"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1 2">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="82" mass="8899" checksum="0617B66396AEE737" modified="2010-04-20" version="1">MAKSREEIVEGLADILEEVAGVEPAKATEDKSFVDDLDVDSLSMVEVVVAAEEKFDVKIPDDDVQSLKTVGDAVSYIEKAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Q8</accession>
    <name>D3Q8Q8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4859"/>
    <dbReference type="EnsemblBacteria" id="ADD44500">
        <property type="protein sequence ID" value="ADD44500"/>
        <property type="gene ID" value="Snas_4859"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4859"/>
    <dbReference type="eggNOG" id="ENOG5032SHQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_146087_0_0_11"/>
    <dbReference type="OMA" id="FWALMIL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025461">
        <property type="entry name" value="ABA4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14108">
        <property type="entry name" value="DUF4281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="150" mass="16302" checksum="5B661A9258A31762" modified="2010-04-20" version="1">MYQAMFNLVFYLAAPFWLLMIVAPTWGWTRRIVGSPLIALPAAAIYVILAVPLLGELLPAVANPTPDGVAELLSTDVGGALGWAHFIAFDLFVGRWEYLDARERGVHPLVMAPVLVLTILLGPLGFVVYLGVRALPLWRKPDDASPTPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8R3</accession>
    <name>D3Q8R3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LOR/SDH bifunctional protein conserved domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020076.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4864"/>
    <dbReference type="EnsemblBacteria" id="ADD44505">
        <property type="protein sequence ID" value="ADD44505"/>
        <property type="gene ID" value="Snas_4864"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4864"/>
    <dbReference type="eggNOG" id="COG1915">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056125_0_0_11"/>
    <dbReference type="OMA" id="GHKHHIY"/>
    <dbReference type="OrthoDB" id="718059at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd12144">
        <property type="entry name" value="SDH_N_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005239">
        <property type="entry name" value="CHP00300"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007545">
        <property type="entry name" value="LOR/SDH_bifunc_enz_cons_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04455">
        <property type="entry name" value="Saccharop_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00300">
        <property type="entry name" value="TIGR00300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Saccharop_dh_N" evidence="1">
        <location>
            <begin position="5"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="412" mass="44398" checksum="798C5B6239230652" modified="2010-04-20" version="1">MVYSETVEIRGHILDSGTFARVLDDVLEYSGDYRIEKLDVGRTHTDESYVKLTVLNDDHEQLDRIVMRLQTHGANKIDPGTALLRPAPHDGVFPDDFYSTTNLDTKVRVEGTWIKVVNPEMDCGIVIDGEIARTIPVSDVRAGEQIVCGINGVKVTPLPEPERGDPSESSFEFMTSEVSSEKPQALLVRQVAEKMRDVKARGEKILWVGGPAIVHTGAAPALVALIEEGYVDVLFAGNALATHDIESALYGTSLGVDLDKGHGVPHGHEHHIRAINRIRAAGSIADAVSEGVLRSGVMHAMVNKGKQFVLVGSVRDDGPLPDVYTDVIDGQRAMRRALDGVGFAIMVATMLHSIATGNMLPATVPLVSVDINPATVTKLADRGSAQATGVITDIGLFCEQLASELVVGYKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8R7</accession>
    <name>D3Q8R7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4868</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4868"/>
    <dbReference type="EnsemblBacteria" id="ADD44509">
        <property type="protein sequence ID" value="ADD44509"/>
        <property type="gene ID" value="Snas_4868"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4868"/>
    <dbReference type="HOGENOM" id="CLU_2036608_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="121" mass="13642" checksum="F48F724A175D61A7" modified="2010-04-20" version="1">MTQLDLILETYVHATSESVAGAVSEPGFARELWPLWSVVVSEDRGPLGVRWLLDDARYSGSTEVWVEAVASDACVLHTFVRVDRRGGSVSAWRRRRVRDRMVKTLWRFKDDVEGRVAHSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8U7</accession>
    <name>D3Q8U7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4898</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4898"/>
    <dbReference type="EnsemblBacteria" id="ADD44539">
        <property type="protein sequence ID" value="ADD44539"/>
        <property type="gene ID" value="Snas_4898"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4898"/>
    <dbReference type="HOGENOM" id="CLU_2384731_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048952" evidence="2">
        <location>
            <begin position="30"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="94" mass="9163" checksum="7228B01B9DF9DE14" modified="2010-04-20" version="1">MRRGAVYVLVTGLVAVAAGVLVFITVASASSPEDLGPKVTVPSEPTAPDGGSGSDDGATKVPGPSPSTAGGEEDDDNDDAGEDGSDDADDDADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9A3</accession>
    <name>D3Q9A3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2910</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018156.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2910"/>
    <dbReference type="EnsemblBacteria" id="ADD42585">
        <property type="protein sequence ID" value="ADD42585"/>
        <property type="gene ID" value="Snas_2910"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2910"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_5_1_11"/>
    <dbReference type="OMA" id="VQEGVQM"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="5">
        <location>
            <begin position="15"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="4">
        <location>
            <begin position="236"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="372" mass="39235" checksum="383B9FB07D259296" modified="2010-04-20" version="1">MNTLPTPPAADLLYSETETELRASLRRLLDDRCPPEWVVSGYDTTLDASGLWKAIAVDLGLAAILIPESCGGAGLGAREAAVVLEELGRAAAPVPFLSSAVLATVALSTIGERETLRRLASGDSTAALAVPLSTSPDDLTPTVSADDTGLTGRITTVAGTELADVLLVPVSDGDGVQLHQVTLPADGVTMTPATALDMTRPLTDITLSGAASTRIDSGDAEAAIRQALLCAAALLPSEQYGVASWCLDTTLAYLKQRRQFGRTIGSFQAVKHRMANLWLQVGQTGALARYAADTYARRDLDTEIAVCVAQSFCGDAAVLAAEECVQLHAGIAMTWEYPAHLYLKRAKADQLALGAAHRYRNRLSQLVDLPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9L2</accession>
    <name>D3Q9L2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transglutaminase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4917</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020129.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4917"/>
    <dbReference type="EnsemblBacteria" id="ADD44558">
        <property type="protein sequence ID" value="ADD44558"/>
        <property type="gene ID" value="Snas_4917"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4917"/>
    <dbReference type="eggNOG" id="COG1305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008359_1_0_11"/>
    <dbReference type="OMA" id="GFCVHFS"/>
    <dbReference type="OrthoDB" id="1043186at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025403">
        <property type="entry name" value="DUF4129"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021878">
        <property type="entry name" value="TgpA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13559">
        <property type="entry name" value="DUF4129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11992">
        <property type="entry name" value="TgpA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="3">
        <location>
            <begin position="477"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="548"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="794" mass="86215" checksum="B0A365284C1998E4" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9L4</accession>
    <name>D3Q9L4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4919</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020131.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4919"/>
    <dbReference type="EnsemblBacteria" id="ADD44560">
        <property type="protein sequence ID" value="ADD44560"/>
        <property type="gene ID" value="Snas_4919"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4919"/>
    <dbReference type="eggNOG" id="ENOG502ZN89">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080168_2_0_11"/>
    <dbReference type="OrthoDB" id="1785628at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070273">
        <property type="term" value="F:phosphatidylinositol-4-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008628">
        <property type="entry name" value="GPP34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038261">
        <property type="entry name" value="GPP34-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05719">
        <property type="entry name" value="GPP34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="24214" checksum="00AA5168D5823521" modified="2010-04-20" version="1">MNDRLPVRDELYLLAHNESGKPLIAMPLLGLGLAAALLIELTMSRHVDVDFDKVVTRPQPANFSQRSLSSIANNALSELYRSRNRPPSPVNVLLVWSEDIYERVRGELLAANLVSPITVRRFGLLSGTEYRSDEAAIVRSRTALRRVVMSEASPSAEDAALCGLLVDLQLERSLHLNVNAGWLRQMLKSIGARQPIPIRRIVDALTEAVRYKSTHGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9S2</accession>
    <name>D3Q9S2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020189.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4980"/>
    <dbReference type="EnsemblBacteria" id="ADD44618">
        <property type="protein sequence ID" value="ADD44618"/>
        <property type="gene ID" value="Snas_4980"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4980"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_11"/>
    <dbReference type="OMA" id="YGTRGIT"/>
    <dbReference type="OrthoDB" id="1294334at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="241" mass="24693" checksum="A1F7612CE673127D" modified="2010-04-20" version="1">MSRIVIVTGGGTGIGRAVAARFAEAGDSVVITGRRQAVLDKTVADLGGDIRAITCDHTDPEQLAALAAALPERVDVLVNNAGGNTDIGTETPSGLAGLGRAWLANLDTNLISAALTTEAIGERLGSGGSVIHIGSIAADKGNGFYGAAKAGLASWNIGLARELGTRDITSNVISPGYISETEFFGDVMTEQRRAALIEATFVKRVGIPADIAGAAWFLASPDARYVTGQTLNVNGGAWSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9T5</accession>
    <name>D3Q9T5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020202.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4994"/>
    <dbReference type="EnsemblBacteria" id="ADD44631">
        <property type="protein sequence ID" value="ADD44631"/>
        <property type="gene ID" value="Snas_4994"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4994"/>
    <dbReference type="eggNOG" id="COG1920">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_203151_0_0_11"/>
    <dbReference type="OMA" id="MQATSFT"/>
    <dbReference type="OrthoDB" id="2065806at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="65" mass="6931" checksum="63ED006AF33FBFAC" modified="2010-04-20" version="1">MQGTVASFDPETRDGGVLLDDGTPVSFSATAFDASRLRLLRLGQRVQLETGADGAVVRLRLPTMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9U3</accession>
    <name>D3Q9U3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD linked oxidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020210.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5002"/>
    <dbReference type="EnsemblBacteria" id="ADD44639">
        <property type="protein sequence ID" value="ADD44639"/>
        <property type="gene ID" value="Snas_5002"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5002"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017779_0_1_11"/>
    <dbReference type="OMA" id="PLNASCW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="26"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="450" mass="46444" checksum="49736282733F735E" modified="2010-04-20" version="1">MTTEIFDRLAEACDGRVTLGTSEDAVCGLVPSYVAAPGSEGDVAALLRVADECGLSVTPRGAGTKLHWGPTPRGCELILDMSRFDRVIDHADGDMVVEVEAGCRLDRLSETLAVAGQRLAVDVPRYDDDTHAVGTVGGLIATGHAGPLRLSYGAVRDLLLGVTMVRADGVVARAGGRVVKNVAGYDLGKLLTGSFGTLGVVTSAIFRLHPLPEATAWVAVTTADPAGAARHASALIDSQQVPTTVDMDRPGVTAPITVAASFEGTAEGVAARAVRAAAAVDGKVMVNPVNGHAEHVAAGADSEVVAEPDPGGAATEPLVWHGSWPDSPHGTLVAVTVPPAALPAAMEAVAQAARANDLDVPARGSAVGVIHTAIPPEAEPGTVASFVAALRDRVRGRDGSTVVVHAPDAVRQRVDMWGPVDDGALDLMRRVKNEFDPRHRLSPGRFVGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9V5</accession>
    <name>D3Q9V5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020222.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5014"/>
    <dbReference type="EnsemblBacteria" id="ADD44651">
        <property type="protein sequence ID" value="ADD44651"/>
        <property type="gene ID" value="Snas_5014"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5014"/>
    <dbReference type="eggNOG" id="ENOG5033QUP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_622430_0_0_11"/>
    <dbReference type="OMA" id="WAMAMIT"/>
    <dbReference type="OrthoDB" id="1753189at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="397" mass="39293" checksum="41BEB6D7C20CB32E" modified="2010-04-20" version="1">MSYRQLATRPVLVWALVAFSARLPVAMAPLALVFLVRERAGGYAVGAGLAAAYVIGEVVGAVVLGPRLRPERARVPLAIGMAVGAGAFAGLGLMPGGDPLVLGALAALAGAAPAAATGGLRALLTSRLPESLVVKALSAESVLTYAVWAVSPALATVLALSVAPPSPLLLAAALLAAATAGMWALPAGWTADDDDRAGVSMARTLLRGWPIYVTGAAALSMLALAELVLPALLEQRGIGVGWAGPLLAGFAIASAAGAALYGLRGSWPGSLRAQSLVLLLGVTGCVALVGVAGSLVWIAGALLVAGLLASGVQVTRNLSLREALPPSAHAAAYSVLYAAVGVGYAASAGLAGVVQSAASPSVAILAGVGFTLVLVGASAVGELRPRRRAAEAVSRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA98</accession>
    <name>D3QA98_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Molybdenum transport system permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_1100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016381.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1100"/>
    <dbReference type="EnsemblBacteria" id="ADD40810">
        <property type="protein sequence ID" value="ADD40810"/>
        <property type="gene ID" value="Snas_1100"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1100"/>
    <dbReference type="eggNOG" id="COG4149">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_14_1_11"/>
    <dbReference type="OMA" id="MYSFIET"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011867">
        <property type="entry name" value="ModB_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006469">
        <property type="entry name" value="NifC_ABC_porter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01581">
        <property type="entry name" value="Mo_ABC_porter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02141">
        <property type="entry name" value="modB_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="50"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD40810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="27085" checksum="99C534AAD8CE3FBB" modified="2010-04-20" version="1">MRHRRAPLGLGLPALIALAFLTLPLLALLAKVPWRRFGDILVESATVEVLVLSVGSAAVSTLLCLLLGAPLAWVLAHARPATRRILRTLVTLPMIVPPVVGGVALLAAYGRRGVAGAPVYELFGVSLPFTTAAVVVAQTFVALPFCVLAIEGALRGIDPEYADSAAVQGAGRFQVFRYITLPLAAPGVVAGATLGFARALGEFGATLTFAGSFPGVTRTAPLAIYQALDSDPALAYGLSAILLLVSAAVLLSLRDSWWPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAB0</accession>
    <name>D3QAB0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018264.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3022"/>
    <dbReference type="EnsemblBacteria" id="ADD42693">
        <property type="protein sequence ID" value="ADD42693"/>
        <property type="gene ID" value="Snas_3022"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3022"/>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039719_0_0_11"/>
    <dbReference type="OMA" id="DIGDLHQ"/>
    <dbReference type="OrthoDB" id="2176451at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046096">
        <property type="entry name" value="DUF6114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19609">
        <property type="entry name" value="DUF6114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="439" mass="46637" checksum="A37A6F7B207F4706" modified="2010-04-20" version="1">MSTTAETIRRWWRAFTAWRRDRPFWGGVLTIAGALELLALTAAPLQIMLIRGLAGIGTLVIAAMLIALAIISWTHGHLRVICGVFIVILGLASFAVSNLGGFFIGLLLALVGGSLIFAWQPGKPPDADETATEEIPPVPAAETAEESDRTTADMTVRAPSPVITPAGRAPSRPRLILRVASVLAVVAAAFVAVPQASAQQTRPSADPTWPCPDWPWPWPCDDSSEPDDPGDDDPDDPGDDEPDKPGDDDPDKPEKPDEECDESKLPAKPPKLGTEAAKKTAKALAACLAQPGSGDAEGRDLPTASTYHPLLNADVMTMTGMNSGGAVDVPTADGKQRALEFTMDTLDLYNMDQASGIEGTKAQLHVINMGSSAVLSGGVRLYVQRMEGLIFGVVPIVITADLPLPPIPVPYLVVTEAKVQTAYVRADRVDLPDLEEPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAC9</accession>
    <name>D3QAC9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium:dicarboxylate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3041</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018283.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3041"/>
    <dbReference type="EnsemblBacteria" id="ADD42712">
        <property type="protein sequence ID" value="ADD42712"/>
        <property type="gene ID" value="Snas_3041"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3041"/>
    <dbReference type="eggNOG" id="COG1301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019375_7_1_11"/>
    <dbReference type="OMA" id="YFCTTII"/>
    <dbReference type="OrthoDB" id="781228at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="415"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="441" mass="46108" checksum="2FBF26E5D1D6A453" modified="2010-04-20" version="1">MLAFLRKIPFSAQLLAGLVVGLGLGYLARTADLGWLTTTLQQVGDLFVQLLKLAVPPLVFTAIVISIANLRKVSNAARLVGKTIGWFMITSLIAVAVGLGLGLLTNPGSGVDISTKGAEAPDHAGSWTDFITGIIPTNIVDSFVQVNVLQIVFIAIVVGAAAVAVGDKAKPFLSFNQSLLDLVQKVLWWIIRLAPIGTAGLIGTAVATYGWSLLAPLATFSIDVYVGCLIVLLGVYPLLLGLVGRVNPVTFFRKSWPAIELAFASRSSVGTMPLAQRIVTKRLGVDKDYASFASPFGATTKMDGCAAIYPALAAIFVAQVFGVNLSIGDYLLIAFVSVVGSAATAGLTGAIVMLTLTLSTLGLPLEGVGLLLAIDPVLDMIRTATNVAGQMVVPVLVSRGEKTLDVAVFNAPNQPLDGSDAVQRPERETGVVREPEPAFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAE3</accession>
    <name>D3QAE3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA/rRNA methyltransferase (SpoU)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3055"/>
    <dbReference type="EnsemblBacteria" id="ADD42726">
        <property type="protein sequence ID" value="ADD42726"/>
        <property type="gene ID" value="Snas_3055"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3055"/>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021322_3_1_11"/>
    <dbReference type="OMA" id="FLAEGPQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="236" mass="24304" checksum="35D8C152A3D9AC02" modified="2010-04-20" version="1">MAEGPQAVAEAVRAGGVTEVFATEAALSRHTGLLAEAESFGARVFAVADSGLAALTDTVHPQGIVAVCGYVDTTLPETVRLAVVLDGIADPGNAGTILRTADAAGAQAVVFPHGSVDPYNGKCVRASVGSLFHLPVVRGGDTDEHLDALRAKGLRILAADVRGETDLDAAIDDGLLRQPTAWLFGSEAHGLSDALTERADVRVRVPIYGAAESLNLATAAAVCLYASAREHRKGET</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAN2</accession>
    <name>D3QAN2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020249.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5041"/>
    <dbReference type="EnsemblBacteria" id="ADD44678">
        <property type="protein sequence ID" value="ADD44678"/>
        <property type="gene ID" value="Snas_5041"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5041"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_19_3_11"/>
    <dbReference type="OMA" id="PDVWDLP"/>
    <dbReference type="OrthoDB" id="1846332at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="148" mass="16276" checksum="CEDE74A598201CEA" modified="2010-04-20" version="1">MTISADGPERVQIVTGLLRDGDRVLLCHRSPGRRWYPDVWDLPGGHVEAGEDPRQSLVRELREELGITASKPSGPPMHQFRTATIDMRIWLVDSWTGTPVNAAPDEHDAVAWFATADLDGLRLAHESHHAMLTAVLDQKPWTGGAGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAT1</accession>
    <name>D3QAT1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5092</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020298.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5092"/>
    <dbReference type="EnsemblBacteria" id="ADD44727">
        <property type="protein sequence ID" value="ADD44727"/>
        <property type="gene ID" value="Snas_5092"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5092"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_39_5_11"/>
    <dbReference type="OMA" id="TIAWTIV"/>
    <dbReference type="OrthoDB" id="446363at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="14"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="493" mass="51977" checksum="23F523AFDE8FEEAD" modified="2010-04-20" version="1">MTLPPVTQGKPRKAALAAWIGSALEYYDFFIYGTAAALVFGKIFFPESDPATGTLLALATFGVGYVARPVGAFFLGHVGDKSGRKKVLVFTIILMGVSTFLVGCLPTYADIGVAAPILLVTLRLAQGLSAAGEQAGANSMSLEHSPSHRRAFYTSFTLSGTQAGQILATAAFLPIAALPEDQLLAWGWRIPFWLSAVVVVAGLVIRRRLDETPVFAAVRDEVPKLPLAVLLRHHWADVLRVIAAALVASVSTIFTVYALSYAVNTVALDRGAMLWVGVIANVVALAAIPLWATISDRVGRKPVMLVGSVGSALLMFAYLWAISIGNLALVFAVGILMFGVVYSAANGIWPSFYGEMFTAKVRLSGMAIGTQFGFAISAFMPTIADGIAGPGAGGWLLPSLLVAGLCAVNVVAVLSSRETYRVPTEELGRAALLGLAAGRGLDPRGPGHADDHRADGDPAARVLGLGLLGGGVRARRTAVVARRPGTRRRFRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAU5</accession>
    <name>D3QAU5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020312.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5106"/>
    <dbReference type="EnsemblBacteria" id="ADD44741">
        <property type="protein sequence ID" value="ADD44741"/>
        <property type="gene ID" value="Snas_5106"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5106"/>
    <dbReference type="eggNOG" id="COG3173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_586216_0_0_11"/>
    <dbReference type="OMA" id="CRVANIA"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="202"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="440" mass="49553" checksum="94A6A5A7EFAB0832" modified="2010-04-20" version="1">MLPVDIRALVPHPEGTAVWVIETDGGLALPSVTIDADGPNDDLAPKLAALAKAHGIDSPFLRRVGLTKHDGRDLILKEFEPLPATGRRWLPLDELARLDLPEDLRPALATWTAYQRGAEYPEFRPAWTRPGWHASTRRWLTDQLTRRDIEPVGEPTLVQQWAISSVLKQPTREHGDHYLKSVFGSPGRAFWHEPALSATLAREHPGQVPAVTTIDSDRGLMLMPDMGITYVDEFPVERWDGGLRVLAEIQRHWANRRDELLALGCPDRDFATTADQLAAALADPLFADKLDPAVHKRVSELMPRWRQLLLDATQWPVPLSLSHGDFHPGNVGLRADGSTCVFDWSDGAWSHPFLDVEVYVRNSGEAQTRLWDVYLDHWTDYAPLSELRQLIPSVNLLGLLYRTVTYHGLLTNVDPDDRFVFGEFAELHWTKSLEAWDAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAU9</accession>
    <name>D3QAU9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">4-hydroxy-tetrahydrodipicolinate reductase</fullName>
            <shortName evidence="9">HTPA reductase</shortName>
            <ecNumber evidence="9">1.17.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapB</name>
        <name evidence="12" type="ordered locus">Snas_5110</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:35323"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NADP(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:35331"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the DapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.8" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5110"/>
    <dbReference type="EnsemblBacteria" id="ADD44745">
        <property type="protein sequence ID" value="ADD44745"/>
        <property type="gene ID" value="Snas_5110"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5110"/>
    <dbReference type="eggNOG" id="COG0289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047479_0_1_11"/>
    <dbReference type="OMA" id="HHPNKAD"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016726">
        <property type="term" value="F:oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00102">
        <property type="entry name" value="DapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022663">
        <property type="entry name" value="DapB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022664">
        <property type="entry name" value="DapB_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023940">
        <property type="entry name" value="DHDPR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20836">
        <property type="entry name" value="PTHR20836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05173">
        <property type="entry name" value="DapB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000161">
        <property type="entry name" value="DHPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00036">
        <property type="entry name" value="dapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01298">
        <property type="entry name" value="DAPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="6 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DapB_N" evidence="10">
        <location>
            <begin position="9"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="DapB_C" evidence="11">
        <location>
            <begin position="116"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="(S)-2,3,4,5-tetrahydrodipicolinate binding" evidence="9">
        <location>
            <begin position="150"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="15"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="83"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="110"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>(S)-2,3,4,5-tetrahydrodipicolinate</name>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD44745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="253" mass="26593" checksum="416EB4C7E2B642AE" modified="2010-04-20" version="1">MSEVAPDAIRVGVLGARGRMGTEVCKAVDAAPDMELVAMVEVGDWLFNMSDAGAEVVIDFTRPEVVMDNLHWCIDQGIHTVVGTTGFTPERIKRVEHWLSAKPGLGSIIAPNFGIGAVLMMRFAQAAAKHFESAEVVEFHHPNKVDAPSGTATRTAELIAAARKEAGLGASPDATTQALDGARGADVEGVKVHAVRSAGMIAHQEVILGGAGETLTLRHDSVDRASFMPGVLLATRAVRSKPGLTVGIDSLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB48</accession>
    <name>D3QB48_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein serine/threonine phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1155"/>
    <dbReference type="EnsemblBacteria" id="ADD40865">
        <property type="protein sequence ID" value="ADD40865"/>
        <property type="gene ID" value="Snas_1155"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1155"/>
    <dbReference type="eggNOG" id="COG0631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034545_0_2_11"/>
    <dbReference type="OMA" id="MLNAQFF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017018">
        <property type="term" value="F:myosin phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="267" mass="27886" checksum="9A498ED4C6F301A3" modified="2010-04-20" version="1">MDIGRRRAACLDIMVTLRHAAASHIGLVYDHNEDSYVDSARLLAVADGVGGAAAGEVASALVAEALRKLSKSKPTAEPGEALRRAVDEANNNIGVAADENSDYRGMATTVTALLFTETRLDLAHAGDSRAYRLRGSELTRLTRDDSYIQGLLDEGALTPEEAAVHPYRSVVTKVLQGFPTEPDCQTLEAELGDRYLVCSDGLSDVVSEADIAATLGQADSPGAAADKLVEQALAAGGPDNVTVVVGQVVESSGFRDKLSGAVSSVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB61</accession>
    <name>D3QB61_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">D-aspartate oxidase</fullName>
            <ecNumber evidence="6">1.4.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1168</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.1" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016449.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1168"/>
    <dbReference type="EnsemblBacteria" id="ADD40878">
        <property type="protein sequence ID" value="ADD40878"/>
        <property type="gene ID" value="Snas_1168"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1168"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034311_0_0_11"/>
    <dbReference type="OMA" id="MAIRERC"/>
    <dbReference type="OrthoDB" id="912110at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008445">
        <property type="term" value="F:D-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046416">
        <property type="term" value="P:D-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006181">
        <property type="entry name" value="D-amino_acid_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="PTHR11530"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00677">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="5">
        <location>
            <begin position="8"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="297"/>
            <end position="302"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000189-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="318" mass="34147" checksum="F9EE134F580B926F" modified="2010-04-20" version="1">MTGPQGYDALVVGAGVSGLTTAVVLAEAGLAVRVMTSDPPLRTVSAMAGASWGPFLAGHEAVPRWSAVSRAVFVQLAAEYGSGVHLSSGVEAYQNMDAAPRWATEVPDFRDCELGEYPTGYKGAWRYTIPLVDMPSYLSYLSQRLSYCGGGIDVIAPLTSLSVPLSVAPVVVNCTGLGARELLDDVDVVPCRGQLTVVENPGITDFFQDNIDGDDLTCIFPHGDKVVLGGTTETNVDAMTYDPNQERQILDRCARIDPRLAGARVVERRVGLRPQRSRIRVERDPNLDGLIHNYGHGGSGVTLSWGCAMDVLKLVRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBE0</accession>
    <name>D3QBE0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dihydroorotase</fullName>
            <shortName evidence="5">DHOase</shortName>
            <ecNumber evidence="5">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pyrC</name>
        <name evidence="7" type="ordered locus">Snas_3151</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(S)-dihydroorotate + H2O = H(+) + N-carbamoyl-L-aspartate</text>
            <dbReference type="Rhea" id="RHEA:24296"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="EC" id="3.5.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018393.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3151"/>
    <dbReference type="EnsemblBacteria" id="ADD42822">
        <property type="protein sequence ID" value="ADD42822"/>
        <property type="gene ID" value="Snas_3151"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3151"/>
    <dbReference type="eggNOG" id="COG0044">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015572_1_0_11"/>
    <dbReference type="OMA" id="QHAQEPR"/>
    <dbReference type="OrthoDB" id="1319925at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01317">
        <property type="entry name" value="DHOase_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00220_B">
        <property type="entry name" value="PyrC_classI_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004722">
        <property type="entry name" value="DHOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="6">
        <location>
            <begin position="48"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="58"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="321"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="432" mass="45386" checksum="CF3155E100287B73" modified="2010-04-20" version="1">MNRWLITGATLPDGTRADILIDDGRVSQVGAVGSATEATIVDADGLVALPGLVDLHTHLREPGREDAETVASGSRAAARGGYTAVCAMANTDPVADTAGVVEQVHSLGRTAGYVEVQPIGAVTVGLAGQRLAELGAMATSAAKVRIFSDDGHCVSDPRLMRRALEYVKAFDGVIAQHAQDPQLTIDAQMHEGEVSARLGLAGWPAVAEEAVIARDALLAGHVGSRLHVCHVSTAGSVEILRWAKSKGWRVTAEVCPHHLLLTDELAATYDPVYKVNPPLRTEADVLALRAGLADGTIDVVATDHAPHTVEDKECEWAAAKPGMLGLETALPIVIKTMHETGSLDWNAVAERCSRTPARIAGLADHGNDPAPGVPANLTLVDPAARWTVEPGELTGPSRNTPYKGLELPGRVIATFFNGRPTVLDGKLQEATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBR2</accession>
    <name>D3QBR2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5166"/>
    <dbReference type="EnsemblBacteria" id="ADD44801">
        <property type="protein sequence ID" value="ADD44801"/>
        <property type="gene ID" value="Snas_5166"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5166"/>
    <dbReference type="eggNOG" id="COG1997">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190603_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_L37ae/L37e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="49" mass="5572" checksum="485DC830540FBC73" modified="2010-04-20" version="1">MSNSRAVPYFCPYCGDEDLRPHEDGGWHCRSCTRVFTVTIKGLVIHDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBX8</accession>
    <name>D3QBX8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5753 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020438.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5233"/>
    <dbReference type="EnsemblBacteria" id="ADD44867">
        <property type="protein sequence ID" value="ADD44867"/>
        <property type="gene ID" value="Snas_5233"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5233"/>
    <dbReference type="eggNOG" id="COG1426">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055817_1_1_11"/>
    <dbReference type="OMA" id="KGWWHAY"/>
    <dbReference type="OrthoDB" id="1114053at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043917">
        <property type="entry name" value="DUF5753"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19054">
        <property type="entry name" value="DUF5753"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5753" evidence="1">
        <location>
            <begin position="97"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="272" mass="31317" checksum="BE15836E481E88D0" modified="2010-04-20" version="1">MTDNPLLTRKQLGKMLRELRLSSGKTVEDIEYFGKLWKKSKLYAIENGHQPNPSWPEVEAVAKFLGASNELTRELVRMAKACLNSGWYVPFDISQKFQTYLDLESAANRLHFVEIEMVNGLFQTENYTRALQRALGVPEEKIQNYVDFRMQRAQRFWNRDPFPEVTLLMSEGTLRRVVGGAEVMAEQVDHLRELARRDLVDIVVIPFAAGLNAAMQNAFTLLEFNDDVYPEVAYVESRSECQYHERKPVVALYKWILQEALSVALPIGEIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU05</accession>
    <name>D3PU05_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenylacetate-CoA oxygenase, PaaJ subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1241"/>
    <dbReference type="EnsemblBacteria" id="ADD40951">
        <property type="protein sequence ID" value="ADD40951"/>
        <property type="gene ID" value="Snas_1241"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1241"/>
    <dbReference type="eggNOG" id="COG2151">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082133_0_0_11"/>
    <dbReference type="OMA" id="EPFDHFK"/>
    <dbReference type="OrthoDB" id="1668114at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011883">
        <property type="entry name" value="PA_CoA_Oase4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02159">
        <property type="entry name" value="PA_CoA_Oxy4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="1">
        <location>
            <begin position="9"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="164" mass="17836" checksum="F58FEE1353C73BF7" modified="2010-04-20" version="1">MVNVRDIAGGVLDPELPQLTIDELGILRDAHAEGQRAVVTITPTYTACPALETIRADIATALRDEGWAEIDIHTVFAPAWSSDWITDSGREKLERAGIAPPGAMPETGVRNLPLLPPPAPRCPRCESTDVEQLSRFGPTACLALWRCRGCAEPFEYFKSHLSCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU69</accession>
    <name>D3PU69_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Release factor glutamine methyltransferase</fullName>
            <shortName evidence="6">RF MTase</shortName>
            <ecNumber evidence="6">2.1.1.297</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N5-glutamine methyltransferase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Protein-(glutamine-N5) MTase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Protein-glutamine N-methyltransferase PrmC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prmC</name>
        <name evidence="9" type="ordered locus">Snas_1306</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42896"/>
            <dbReference type="Rhea" id="RHEA-COMP:10271"/>
            <dbReference type="Rhea" id="RHEA-COMP:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.297"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.297" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1306"/>
    <dbReference type="EnsemblBacteria" id="ADD41015">
        <property type="protein sequence ID" value="ADD41015"/>
        <property type="gene ID" value="Snas_1306"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1306"/>
    <dbReference type="eggNOG" id="COG2890">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018398_4_0_11"/>
    <dbReference type="OMA" id="FDARYWE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:protein-(glutamine-N5) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02126">
        <property type="entry name" value="RF_methyltr_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040758">
        <property type="entry name" value="PrmC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019874">
        <property type="entry name" value="Release_fac_Glu-N5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17827">
        <property type="entry name" value="PrmC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03534">
        <property type="entry name" value="RF_mod_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PrmC_N" evidence="8">
        <location>
            <begin position="8"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="MTS" evidence="7">
        <location>
            <begin position="105"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="187"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD41015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="291" mass="30276" checksum="987EB0C2C54DD47B" modified="2010-04-20" version="1">MGTGWRALLDEATRRLTESGVDSPRVDAEFLAAHVAGVSRGGLFAAAAPTSAQAKKFRSLVERRAAREPLQHVLGTAPFRYAELAVGPGVFVPRPETEQLAEWALARLATVAAPLVVDLCAGSGAIGHAIVSERPDAVVVLVEKYPEAANWLRRNLDGVAARVVEADAVSPETLSDLDGQCDAVLSNPPYVPTSTAVSPEVAADPATAVFGGSCGLDVIRPLIPRAARLLRPGGVVAIEHDDSHGAVVPELLTAAGFADATDHDDLTGRPRFATATLPPRGLARLAGCEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUB9</accession>
    <name>D3PUB9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyrimidine-nucleoside phosphorylase</fullName>
            <ecNumber evidence="6">2.4.2.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1357</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.4" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1357"/>
    <dbReference type="EnsemblBacteria" id="ADD41065">
        <property type="protein sequence ID" value="ADD41065"/>
        <property type="gene ID" value="Snas_1357"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1357"/>
    <dbReference type="eggNOG" id="COG0213">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025040_0_1_11"/>
    <dbReference type="OMA" id="DVWRRMI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004645">
        <property type="term" value="F:1,4-alpha-oligoglucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016154">
        <property type="term" value="F:pyrimidine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009032">
        <property type="term" value="F:thymidine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006206">
        <property type="term" value="P:pyrimidine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006213">
        <property type="term" value="P:pyrimidine nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036566">
        <property type="entry name" value="PYNP-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013102">
        <property type="entry name" value="PYNP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018090">
        <property type="entry name" value="Pyrmidine_PPas_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017872">
        <property type="entry name" value="Pyrmidine_PPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000053">
        <property type="entry name" value="Thymidine/pyrmidine_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10515">
        <property type="entry name" value="PTHR10515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07831">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000478">
        <property type="entry name" value="TP_PyNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00941">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54680">
        <property type="entry name" value="SSF54680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02644">
        <property type="entry name" value="Y_phosphoryl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00647">
        <property type="entry name" value="THYMID_PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PYNP_C" evidence="5">
        <location>
            <begin position="335"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="424" mass="43596" checksum="B3CDACAE23C0B47B" modified="2010-04-20" version="1">MFSAVDVIRAKRDGGELTTAQIDWVIDAYTKGVVADEQMSALAMAILLNGANDREIADWTAAMIASGERLDLSGVGKPTVDKHSTGGVGDKITLPLAPLVAAFGVAVPQLSGRGLGHTGGTLDKLESIPGWRANLSNAEFIARLSDPGAVVCAAGDDLAPADRRLYALRDVTGTVESIPLIASSIMSKKIAEGTDALVLDVKVGSGAFMKDAEQARRLAETMVRLGDAHGVRCTALLTDMDTPLGRTAGNALEVTESLEVLAGGGPADVVELTVALAREMLALAGKPDADPAAALADGRAMDAWRAMISAQGGDVDAKLPVAPESEEVRAESDGVVARMDAYAVGVAAWRLGAGRARKSDPVSAGAGVEILKTVGETVSAGEPLLRLHTEDVSTFAAARTTLDGAIDIGGSTAKRQLIMARIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUI0</accession>
    <name>D3PUI0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YhgE/Pip N-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3327</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018564.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3327"/>
    <dbReference type="EnsemblBacteria" id="ADD42993">
        <property type="protein sequence ID" value="ADD42993"/>
        <property type="gene ID" value="Snas_3327"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3327"/>
    <dbReference type="eggNOG" id="COG1511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004534_1_1_11"/>
    <dbReference type="OMA" id="ISWTIAD"/>
    <dbReference type="OrthoDB" id="1240965at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017500">
        <property type="entry name" value="Phage_infect_YhgE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023908">
        <property type="entry name" value="xxxLxxG_rpt"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03061">
        <property type="entry name" value="pip_yhgE_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03057">
        <property type="entry name" value="xxxLxxG_by_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="502"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="537"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="564"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="615"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="649" mass="66494" checksum="2DFD595A87B36B0B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUP4</accession>
    <name>D3PUP4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase U61 LD-carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3393</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S66 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3393"/>
    <dbReference type="MEROPS" id="S66.001"/>
    <dbReference type="EnsemblBacteria" id="ADD43057">
        <property type="protein sequence ID" value="ADD43057"/>
        <property type="gene ID" value="Snas_3393"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3393"/>
    <dbReference type="eggNOG" id="COG1619">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034346_3_1_11"/>
    <dbReference type="OMA" id="GFIFGQC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027461">
        <property type="entry name" value="Carboxypeptidase_A_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027478">
        <property type="entry name" value="LdcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040449">
        <property type="entry name" value="Peptidase_S66_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040921">
        <property type="entry name" value="Peptidase_S66C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003507">
        <property type="entry name" value="S66_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237">
        <property type="entry name" value="PTHR30237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02016">
        <property type="entry name" value="Peptidase_S66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17676">
        <property type="entry name" value="Peptidase_S66C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028757">
        <property type="entry name" value="LD-carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141986">
        <property type="entry name" value="SSF141986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049471" evidence="4">
        <location>
            <begin position="38"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S66" evidence="5">
        <location>
            <begin position="54"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S66C" evidence="6">
        <location>
            <begin position="215"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR028757-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="344" mass="35709" checksum="01D5DE1436439A17" modified="2010-04-20" version="1">MTQQPPSSFARRSLLGGAAALVGGSVLGVSTSGTAAAHKPTIVRPRKLSEGDVVMLVSPGGSPNATSVDKGIALLESWGLTVRVAEHALDKFGYLSAPDADRLADLNAALADPEVRAVMATRGGYGTQRIIDEVEFPDADPKLIIGYSDITALHLAAYKRADTASLHAPMAAWNSNNTAETEKALRGALFTTDPVVLTRDPAEPTAGVEVAGTASGILLGGNLSMLCSEPENRNGLDLDDAILFIEDVGESPYRVDRLLTELLRAGTLKHVAGVAIGQFTDSTGNPGDWTVAEVLRDRLTPLGVPVIGGLRIGHGADPRVMPLGVPAELDTKAGTLTVEAAVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUZ0</accession>
    <name>D3PUZ0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020585.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5382"/>
    <dbReference type="EnsemblBacteria" id="ADD45014">
        <property type="protein sequence ID" value="ADD45014"/>
        <property type="gene ID" value="Snas_5382"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5382"/>
    <dbReference type="eggNOG" id="ENOG5032ZFQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102900_1_0_11"/>
    <dbReference type="OrthoDB" id="1538348at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018750">
        <property type="entry name" value="DUF2306_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10067">
        <property type="entry name" value="DUF2306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="155" mass="16578" checksum="1CC4BCB879A4F0FB" modified="2010-04-20" version="1">MAIQVIIGIHIAAGLVAVIAGAVAMFAAKRPGRHPVAGRIYLGGLAVLVASACVIVVARPHTAFLLLLGAAALMLAGIGLAARRIRWRGWLAHHIIAMPGSYILALTAFYVDNGPRLPLWRLLPPAWFWFLPAAVGFPLVVWALRRNTAGRVKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV59</accession>
    <name>D3PV59_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016683.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1405"/>
    <dbReference type="EnsemblBacteria" id="ADD41112">
        <property type="protein sequence ID" value="ADD41112"/>
        <property type="gene ID" value="Snas_1405"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1405"/>
    <dbReference type="eggNOG" id="COG1075">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_504222_0_0_11"/>
    <dbReference type="OMA" id="CHSARAY"/>
    <dbReference type="OrthoDB" id="514955at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="540" mass="58098" checksum="3BB4C9BA6433529C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVD1</accession>
    <name>D3PVD1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016755.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1480"/>
    <dbReference type="EnsemblBacteria" id="ADD41184">
        <property type="protein sequence ID" value="ADD41184"/>
        <property type="gene ID" value="Snas_1480"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1480"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128784_0_0_11"/>
    <dbReference type="OMA" id="HWNGYKL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049271" evidence="1">
        <location>
            <begin position="31"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="166" mass="17810" checksum="03C547DCA3E29FBC" modified="2010-04-20" version="1">MKILRIAAKAILGIGLATAIVVAIPSVASANEVEPRAKLSHSQATAKFRDAGITWSSSGNCSDRNNPTCTSFEQIRSETVAGVITLKSASGCAIRLTGGTETGHASGTYSHWNGYKVDFALSTCLNNYIQRFTYIGGSKWKSGSGNIYYKEGNHWDVLYYNCGGCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVK3</accession>
    <name>D3PVK3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018688.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3453"/>
    <dbReference type="EnsemblBacteria" id="ADD43117">
        <property type="protein sequence ID" value="ADD43117"/>
        <property type="gene ID" value="Snas_3453"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3453"/>
    <dbReference type="eggNOG" id="ENOG5032W6J">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108352_0_0_11"/>
    <dbReference type="OMA" id="NAFLARW"/>
    <dbReference type="OrthoDB" id="1972679at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="21467" checksum="2693DC49F8D4E0AC" modified="2010-04-20" version="1">MGRDRLWLSWFGWVTLGECAGFAVPSATYAITPSAPAPVQTALMLAAGCTEGYILGLAQARVLRRVLPGTRHWPTATALGAGIAWVCGLVIAELWSEAVLPLPATAGVTVVLAVTGLMSIGTAQWWLLRGRLARAGWWITGTAAAWVAGLAVFLTVSTPLWHEGQPTGAVVVIGMFAATLMAAAMAAVTGAVLWWLLSATTARSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVN6</accession>
    <name>D3PVN6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_3487</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018721.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3487"/>
    <dbReference type="EnsemblBacteria" id="ADD43150">
        <property type="protein sequence ID" value="ADD43150"/>
        <property type="gene ID" value="Snas_3487"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3487"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_11"/>
    <dbReference type="OMA" id="MYEDALF"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="41"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="365"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="399"/>
            <end position="406"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="616" mass="67073" checksum="5B1C66CC7C480F78" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVR8</accession>
    <name>D3PVR8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3519"/>
    <dbReference type="CAZy" id="GH93">
        <property type="family name" value="Glycoside Hydrolase Family 93"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43182">
        <property type="protein sequence ID" value="ADD43182"/>
        <property type="gene ID" value="Snas_3519"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3519"/>
    <dbReference type="eggNOG" id="COG4409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036301_1_0_11"/>
    <dbReference type="OMA" id="KMVHQTT"/>
    <dbReference type="OrthoDB" id="235722at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049496" evidence="1">
        <location>
            <begin position="43"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="415" mass="43641" checksum="51857B85D5F88A71" modified="2010-04-20" version="1">MPSVSTPVPLGSARPARRWRLVLLLAVLLAGSVLVGVGGADAQPTDAPRSEDTVAAAERQLLRDGVGLYPRAVRLEHNGDANGRVVAGVVSFVGNGDGIGAIYESTDDGATFAEVGQVADPDAAGGQGLCCATLFELPRQVGDMRAGTLLWAASVGADEPDRRMSLRIWRSDDLGRTWSHLSACATAPDAKGLWEPEFSVAADGALVCHYADETDPAHSQKLMHARSADGVTWTDHSPTVASTLASDRPGMPVVRQLPNGTYFMSFEICAPDGQFACVTHYRTSADGWDWGDPAHLGFQPETADGKYFKHAPTITWKADPDSPNGARLFLIGQILFNADGSVAAENGAAVLTNSQGGSGPWELIPSPVAVNAPSNNYCPNYSSTLLPTGDGNALFGIATDYENDVCKPFYGTSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVX8</accession>
    <name>D3PVX8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA polymerase III, delta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020670.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5468"/>
    <dbReference type="EnsemblBacteria" id="ADD45099">
        <property type="protein sequence ID" value="ADD45099"/>
        <property type="gene ID" value="Snas_5468"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5468"/>
    <dbReference type="eggNOG" id="COG1466">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052338_0_0_11"/>
    <dbReference type="OMA" id="QQMRGWT"/>
    <dbReference type="OrthoDB" id="1199768at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005790">
        <property type="entry name" value="DNA_polIII_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01128">
        <property type="entry name" value="holA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="319" mass="32800" checksum="91023D2D1FCA9573" modified="2010-04-20" version="1">MAKTVSGMRLVLGEEELLAERAVAAIVAEARQRDAGIQVHRADAGDLSPGELTTLTSPTLFGGGSVVVVENAQDAKKELAAALNGYLDAPAADVEVVVVHAGGNKGKALAESLRKAGVEVISAAKIKRATDRANFVKEELRRLGARANAAAAEALITAVGHDLRELASACSQLVADTGGKVTVDEINKYYRGRAEVTGFAVADAAVTGDAQAALSGLRWALSVGVDAVPLADALATGVRNIAKVAGARESGYQLASKVGMAPWQVDKAKQQGRGWTPEGLVAAMDVTAELNAAVKGGSEDRAYALERAILAITAARSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW34</accession>
    <name>D3PW34_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_5524</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020726.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5524"/>
    <dbReference type="EnsemblBacteria" id="ADD45155">
        <property type="protein sequence ID" value="ADD45155"/>
        <property type="gene ID" value="Snas_5524"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5524"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_325116_0_0_11"/>
    <dbReference type="OMA" id="YAEYVHQ"/>
    <dbReference type="OrthoDB" id="494360at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025231">
        <property type="entry name" value="DUF4173"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13777">
        <property type="entry name" value="DUF4173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="527"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="565"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="608"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="652"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="684"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="719"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="748"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="69"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="129"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="857" mass="90863" checksum="A358E5C2F62D28DF" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW57</accession>
    <name>D3PW57_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016785.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1510"/>
    <dbReference type="EnsemblBacteria" id="ADD41214">
        <property type="protein sequence ID" value="ADD41214"/>
        <property type="gene ID" value="Snas_1510"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1510"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="ITCAVMI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="174"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="378" mass="39586" checksum="0217E0F8BCFB2B0F" modified="2010-04-20" version="1">MPRLPTRTLFIDTVIALVLGAATAITTIPSVDGEPGEQLIDAGGFAAIALTALSLSFRRVWPLSSLVAVFAGTTAYTLLGYPYGPIFLLMAVAMGSVAAHHSTRVAVITCAVMIVAHLPYSILADSDDDSPLINIAISVTWLVVSTVSGMAFKQAREARDRAKLEERRRYLSEERLHIAREVHDVVGHSLTAIRLHAGVALHVLHRDGVAVPAEVTESLTAIRDSGSAALDELRATLAPLAAAETERPVLTLEDVEAAVTAALTSDELAIDVTVDGQREAIPSVVDSAGYRIVQESLTNVVKHAGASRVAVDIAYAPGLVTIEVVDNGHGAPDSRAEGHGLAGMAERATALGGSFTAGPRDGGGYAVKAELPYATVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWH5</accession>
    <name>D3PWH5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cholesterol oxidase</fullName>
            <ecNumber evidence="4">1.1.3.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3535</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.1.3.6" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018768.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3535"/>
    <dbReference type="EnsemblBacteria" id="ADD43197">
        <property type="protein sequence ID" value="ADD43197"/>
        <property type="gene ID" value="Snas_3535"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3535"/>
    <dbReference type="eggNOG" id="COG2303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040036_0_0_11"/>
    <dbReference type="OMA" id="GWGPNGN"/>
    <dbReference type="OrthoDB" id="365211at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016995">
        <property type="term" value="F:cholesterol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048037" evidence="2">
        <location>
            <begin position="31"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="3">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="533" mass="57744" checksum="D2C2EC77706ABFCE" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX22</accession>
    <name>D3PX22_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5616</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020817.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5616"/>
    <dbReference type="EnsemblBacteria" id="ADD45246">
        <property type="protein sequence ID" value="ADD45246"/>
        <property type="gene ID" value="Snas_5616"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5616"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_1_3_11"/>
    <dbReference type="OMA" id="PWGIAES"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="334"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="613"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1097" mass="117528" checksum="8C0EAE367A0986DE" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX97</accession>
    <name>D3PX97_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide TPR_4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1658</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016931.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1658"/>
    <dbReference type="EnsemblBacteria" id="ADD41360">
        <property type="protein sequence ID" value="ADD41360"/>
        <property type="gene ID" value="Snas_1658"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1658"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_679546_0_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="405" mass="45002" checksum="A96AF62A3D471505" modified="2010-04-20" version="1">MTDVSGPLGPDRTSSVLSMSLDLLRDRGMGNAAPLLKLFACFSTAPIPYVVLLNTNQYKASALFTEDRGGSWSAAVEGLEQLGLVDIHSGRGVGAEELSHVLSMHPLIYATLREDPELKRHHDDYYELALSMLLTAVAGANPDDPDSWPIWRVVTPHALEIVRTVLSRPDTGPRLLTPVLQLARKTGRYLIATGLLKPAAELLNPIVDACESFGIGVDDERILAIRHEVGRVALERGDLRVAETELWQVVEARAALHGMDHPETLASRHKHARAILEQHRWVEAEPLLRDVTDAEIRAWGPEHSDTMVVRHSLARVKLHLGWVAEAEAMLREILVIRYRRWPRTTPETLFVVRSLAQSLVEQDKLDEAESVLREALADAGDRADAPEFQRLSLALERIVQVRQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXI4</accession>
    <name>D3PXI4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018885.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3656"/>
    <dbReference type="EnsemblBacteria" id="ADD43314">
        <property type="protein sequence ID" value="ADD43314"/>
        <property type="gene ID" value="Snas_3656"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3656"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_2_3_11"/>
    <dbReference type="OMA" id="EVELHHE"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="7"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="155"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="289" mass="30566" checksum="69341E27011F99C6" modified="2010-04-20" version="1">MNENNVKPVVVGIDGSRDSLRTLEYAAVEAVSRNLPLRIVHARSWPLYSGDAAVVFAYSAPPLSTDAENQRVIDEAVDTVHHAHPDLPVSGQVIHGGASIVLVGESEHAEIIVIGARGAGGVAEKLLGSVALDVAVRAKCPVLLVRGDTERTGPVAVGIDGKRTSWDAIGFAFAEAEQRKVPLHAIHAWHLSTADAATSTTDEPGVAQANRLLGGWLNDWQPRFPSVETHHVPVHTTDVAAALTDASETAGLLVIGSRMRGELRARLLGSTGYAMIHTSQCPLAIVHNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXR7</accession>
    <name>D3PXR7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018968.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3740"/>
    <dbReference type="EnsemblBacteria" id="ADD43397">
        <property type="protein sequence ID" value="ADD43397"/>
        <property type="gene ID" value="Snas_3740"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3740"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092079_0_0_11"/>
    <dbReference type="OMA" id="IAVGVVW"/>
    <dbReference type="OrthoDB" id="1748559at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="169" mass="18057" checksum="D99ABE5ACC1AF443" modified="2010-04-20" version="1">MSTQARDEVRGYRGPVACNAAGITYRQLDYWARTDLVTPSVRDAEGSGSQRLYSFRDIVVLKVVKSLLDAGVSLQNIRKAIEVLRSRGEHDLANITLISDGTTVYECRSPEEVVDLLRGGQGVFGIALAGAVADIRGSVTALPAVPPGLGPASTPVDELAHRRARRAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY09</accession>
    <name>D3PY09_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferric uptake regulator, Fur family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020909.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5708"/>
    <dbReference type="EnsemblBacteria" id="ADD45338">
        <property type="protein sequence ID" value="ADD45338"/>
        <property type="gene ID" value="Snas_5708"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5708"/>
    <dbReference type="eggNOG" id="COG0735">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096072_4_3_11"/>
    <dbReference type="OMA" id="MKHFAIF"/>
    <dbReference type="OrthoDB" id="1630127at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="15500" checksum="BB7512AA4CB985DE" modified="2010-04-20" version="1">MSVEGSQLAEVLRAHGLRVTAQRQLVLDAVRDLGHATAERVHEAICGKVTGVNITTVYRTLDLLESLGLIAHTHLSHGAPVYHLAGNRGHVHLVCHRCGAVDEIDPEVFDGLRRSLEQQRGFLLDVGHVALFGICASCEKANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY36</accession>
    <name>D3PY36_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5735"/>
    <dbReference type="EnsemblBacteria" id="ADD45365">
        <property type="protein sequence ID" value="ADD45365"/>
        <property type="gene ID" value="Snas_5735"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5735"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_1_2_11"/>
    <dbReference type="OMA" id="YDSFAGA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="2"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="21876" checksum="78FF1EFBDBF62FFB" modified="2010-04-20" version="1">MRKIIAGLFISLDGVVEAPDQWHFPYFNEEMGAAVGNTLGAADIMLFGRETYDSFAGAWPEREAAGGEDAGFAKKLGDVRKIVASHQDLKFTWRNSEQLEGDLVETVTALKNEDDDAVIGMSGSVSVVRQLLAAGLLDELHLLVHPIAVRKGARLFDEGTESIPLKLVSSQAFSTGVLNLVYAPAEAPADAGYEEAKTQLPQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY37</accession>
    <name>D3PY37_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5736"/>
    <dbReference type="EnsemblBacteria" id="ADD45366">
        <property type="protein sequence ID" value="ADD45366"/>
        <property type="gene ID" value="Snas_5736"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5736"/>
    <dbReference type="eggNOG" id="ENOG503315W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131550_1_0_11"/>
    <dbReference type="OMA" id="SGNCVEM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="1">
        <location>
            <begin position="18"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="80" mass="8445" checksum="D53038A301D8A5DF" modified="2010-04-20" version="1">MTMAHNGIPAGQLPATIKWQKSRRSNPSGNCVEMAALPGGAEIAVRNSRDPQGPVLVYTVDEIRALVGGARDGDFDNLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYE8</accession>
    <name>D3PYE8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Methylenetetrahydrofolate reductase</fullName>
            <ecNumber evidence="8">1.5.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_1819</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:19821"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19817"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017086.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1819"/>
    <dbReference type="EnsemblBacteria" id="ADD41515">
        <property type="protein sequence ID" value="ADD41515"/>
        <property type="gene ID" value="Snas_1819"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1819"/>
    <dbReference type="eggNOG" id="COG0685">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081788_0_0_11"/>
    <dbReference type="OMA" id="VYIAHIE"/>
    <dbReference type="OrthoDB" id="1425269at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106312">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106313">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADPH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006555">
        <property type="term" value="P:methionine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0274">FAD</keyword>
    <keyword evidence="5 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD41515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="289" mass="31488" checksum="71B93140A9B12642" modified="2010-04-20" version="1">MSMSAALSRVRMRRTASRLLAEPRFEVLPLERVDREVAALPRGTTVTITASPSRGTMATVETAERFAALGLRPVPHLSARGMRDDAELVEVVQRLDHAGIRDAFVVGGDASSASAVFPDGLALLQAMDDIGHRLHDIGIPAYPEGHPSIDDDTLWAALAAKRRYATYAVTQLCFDAEAICRFTVQARQRGFDLPILAGIPGAVDTAKLLRVGLRIGIGDSLRFVRGNRSVLRKLLRPGGYRPDGLVRKLDGRVRDGRCELAGAHIYTFNDVAATARWLKGRTAVYDHAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYP8</accession>
    <name>D3PYP8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Preprotein translocase, YajC subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_3825</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YajC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3825"/>
    <dbReference type="EnsemblBacteria" id="ADD43481">
        <property type="protein sequence ID" value="ADD43481"/>
        <property type="gene ID" value="Snas_3825"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3825"/>
    <dbReference type="eggNOG" id="COG1862">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116157_1_1_11"/>
    <dbReference type="OMA" id="YNRIVHG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003849">
        <property type="entry name" value="Preprotein_translocase_YajC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33909">
        <property type="entry name" value="PTHR33909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02699">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01323">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00739">
        <property type="entry name" value="yajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="82"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="86"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD43481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="123" mass="13566" checksum="E05305025A991FC3" modified="2010-04-20" version="1">MMPAVIILLMVAMYFFMIRPQNKKRREIMEKQRQAGPGQTIVTIGGLHATIIDADKDTVTLEVSPGVMCVYERGAIARVVDETVETDLTTDDDDSEDEKSEETPASAVVDMKADKSSGDDSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYT8</accession>
    <name>D3PYT8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3866</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019092.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3866"/>
    <dbReference type="EnsemblBacteria" id="ADD43521">
        <property type="protein sequence ID" value="ADD43521"/>
        <property type="gene ID" value="Snas_3866"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3866"/>
    <dbReference type="eggNOG" id="COG0609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013016_7_2_11"/>
    <dbReference type="OMA" id="MFPYQIP"/>
    <dbReference type="OrthoDB" id="1283908at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="457"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="482"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="513"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="555"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="602"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="670"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="700" mass="70858" checksum="2F558A2C28D1D6D8" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ30</accession>
    <name>D3PZ30_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epoxide hydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5829</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021030.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45459">
        <property type="protein sequence ID" value="ADD45459"/>
        <property type="gene ID" value="Snas_5829"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5829"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_2_11"/>
    <dbReference type="OMA" id="WVELMGR"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033961">
        <property type="term" value="F:cis-stilbene-oxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EHN" evidence="4">
        <location>
            <begin position="9"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="395" mass="43741" checksum="D34E3BB7E3C7E1DC" modified="2010-04-20" version="1">MSLLTSDVEAFEAHAAEADLEDLRARLASARLPEVETVYRDAPDPRRWDQGVPLGDLVDVVEYWRTGYDWRAFETRLNRIGQFRTTIDGLGIHFLHRRSRRADATPLVLTHGWPGSIAEFVDVVDELADPESADAPAFHVVVPSLPGFGYSDKPTSTGWGIEKIAAAWVELMGRLGYDRFAAAGGDFGGVITTILGGRFPEHVLGVHTTSPQGPSGLAADGLSMEGLTAVEREWAEETSEFWSGARAAYAKQQAARPQTIGYSLVDSPVGLLAWILDKFAEWTDTKDSPFETISMDRVLDDVTLYWLTRSGASAARLYYESHNSLDPELRVDVPSAITVYPRDVEKVPRPWARERFRRIVRWRSPEAGGHFPSLELPEFFVTDLREGLAAVLAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZT3</accession>
    <name>D3PZT3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3968</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019191.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3968"/>
    <dbReference type="EnsemblBacteria" id="ADD43620">
        <property type="protein sequence ID" value="ADD43620"/>
        <property type="gene ID" value="Snas_3968"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3968"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077370_0_0_11"/>
    <dbReference type="OrthoDB" id="1417316at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="300" mass="32823" checksum="0BB6DC224AB5E806" modified="2010-04-20" version="1">MSKFRNSPALIDILRALSGGETLSANEIRARSGRSFSSAQQKKLTEPGYLVVGKAGRASTFTLTADGMDMASDELDGAEQPSRHAPDQRLGAEERKALFALLSPSLQVSYAEVKRTLGIAIGEGLRHTLADKGLVVVVEGPLRFELTEKGWAVAEAELSRPAEADDPPLLKLLHHHFCLLLAGLRTRGLGLTDMYAESYVDMSTKQAAAPRKVAAETVGARIIDAYDELVYEPGGWVSLTRLREHMSDVEREELDEVLSALFRDGRIKLIAEVNQKTLTHRDREAALHIVGDEKHLYAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q023</accession>
    <name>D3Q023_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5924</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45552">
        <property type="protein sequence ID" value="ADD45552"/>
        <property type="gene ID" value="Snas_5924"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5924"/>
    <dbReference type="eggNOG" id="ENOG502ZNDI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_216330_2_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="43" mass="4707" checksum="48F9A393F8D33945" modified="2010-04-20" version="1">MWKKLIILAGVIGVAAIVAKKVKAMNEERALWHEATTSAEDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q038</accession>
    <name>D3Q038_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021138.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5940"/>
    <dbReference type="EnsemblBacteria" id="ADD45567">
        <property type="protein sequence ID" value="ADD45567"/>
        <property type="gene ID" value="Snas_5940"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5940"/>
    <dbReference type="eggNOG" id="ENOG50335GQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121458_0_0_11"/>
    <dbReference type="OMA" id="YAKCMRE"/>
    <dbReference type="OrthoDB" id="2031675at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049415" evidence="1">
        <location>
            <begin position="34"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="158" mass="16990" checksum="D4B7C0B7A5B6183C" modified="2010-04-20" version="1">MRGRITGVLAAVSLALALTLTGCGGSDDTGSQGESAADKNHEKALKYAKCMREHGVDMEDPEPGEGLKFTAKGGDPKVMEKAQKACEKYQPQGNKGGKGDAKQKEKMLDYSKCMRDNGVEDFPDPTDKGMMIDKDVAEDPDFEDAQKACEKHMPGMGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0A8</accession>
    <name>D3Q0A8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0050</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015343.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0050"/>
    <dbReference type="EnsemblBacteria" id="ADD39772">
        <property type="protein sequence ID" value="ADD39772"/>
        <property type="gene ID" value="Snas_0050"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0050"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_1_11"/>
    <dbReference type="OMA" id="NGMWFAV"/>
    <dbReference type="OrthoDB" id="1074175at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="70"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="278" mass="30907" checksum="9C6E041DCD87869E" modified="2010-04-20" version="1">MTARAKIITTAVLTVVAVYFLLPVYWLIVAATKTTEDLFGSNGLWFSSPRLWTNMVELFTFQDGIYLRWTLNSILYAGVGALCATFICAMAGYGLAKYRFAGREKVFNLVLGGVLLPATALTLPLYLLMSEFSMANTYWAVLLPAMVSPFGVYLCRIYAAAAVPDELLEAARIDGASEFRVFLTVALRIMTPALVTIFLFQFVGIWNNYFLPLIMLSDSNLYPITLGLTSWQGFASRQPILYQLTVGGAFVSVIPLMIMMVVLQRFWRTGLTQGSVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0B9</accession>
    <name>D3Q0B9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015354.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0061"/>
    <dbReference type="EnsemblBacteria" id="ADD39783">
        <property type="protein sequence ID" value="ADD39783"/>
        <property type="gene ID" value="Snas_0061"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0061"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_9_0_11"/>
    <dbReference type="OMA" id="HIDRPEV"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="4"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="27817" checksum="72EDC62E16613F03" modified="2010-04-20" version="1">MSDVVILTGLADSRWTWRPVETALADAGTVLIADRTRHQTFPTLADEIVRVRDLVVGHRLGPPVVVAHSFGALIAEAYARRYPVAGLVLVDPSWDPDATGRGAIEAGLVRAAFHGAGALGKALDVTGLARHLGPALWSLSLRAVALRRPGAGVVAATRSVYRRGETLVAAAAEELAFRDFAAALAKSRATSHAPEVPVVVLTAVGTDPKSRDSRHWIAAHRRLAALFPNGRHEVVRGAKHMMHIDRPEVIVREVNRLLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0H8</accession>
    <name>D3Q0H8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017285.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2019"/>
    <dbReference type="EnsemblBacteria" id="ADD41714">
        <property type="protein sequence ID" value="ADD41714"/>
        <property type="gene ID" value="Snas_2019"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2019"/>
    <dbReference type="HOGENOM" id="CLU_823638_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="337" mass="35712" checksum="27E9DAABFDC6946A" modified="2010-04-20" version="1">MNKQEFIGKLDTAIDGLADAIAKKGVRFPEEFNDIPGASKLGVPEPKHGASHYPKVKPYEPAMRGFIKDESVRLFAPWKNMPDPAGFDAAIQHVVNGRGKIATKDVTSVSDIKQMDLGTQMPGYMVAVRENLADWRGKTIEAAHLNYINLFDEMLFLQANTLRVLELTLKAHQKGISDAQDDTVKLVDSAAAAVDAIDCWGGDSNKNVAFNVVAGVIGVLGAATPGVNAVVALAGAAGGLGIAKDLISSKDPESVPLGASRIDGVWSNLTSALDRHKELYKEGESLLATTITNFNTVLNGNFTTGQGPDGKTVTKPGVELIRLSTPIDLGSVQAPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0U7</accession>
    <name>D3Q0U7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta-lactamase2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019268.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4045"/>
    <dbReference type="EnsemblBacteria" id="ADD43697">
        <property type="protein sequence ID" value="ADD43697"/>
        <property type="gene ID" value="Snas_4045"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4045"/>
    <dbReference type="eggNOG" id="COG2367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050510_3_0_11"/>
    <dbReference type="OMA" id="GYWGLTQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030655">
        <property type="term" value="P:beta-lactam antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045155">
        <property type="entry name" value="Beta-lactam_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000871">
        <property type="entry name" value="Beta-lactam_class-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35333">
        <property type="entry name" value="PTHR35333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13354">
        <property type="entry name" value="Beta-lactamase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048776" description="Beta-lactamase2 domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase2" evidence="2">
        <location>
            <begin position="126"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="283" mass="29933" checksum="0CB8177C3D9DCB3E" modified="2010-04-20" version="1">MRLPAAVVTGVVAVVAVSSVITGTTLAIADGNETDAPKLKNPTSCVSSDPELAERLASQLDAAVAAKPDGIGFSISDPVTQTACHFGSDRVIKTASTIKVTLVAALLHLAQEEGRELTQKEKDNSHAAITVSDNKAATAIYEQLGAERIEAFVATLGMVSTQVRPTWGSSSTTSADQEILLRTLTNPGEILTDPNRAYLLDLMANVVPEQAWGTTDGAPDTVTKHVKNGWVEEYGWTSSLGTFDGADRNYVMAVLTNNSTTLDEGIERIAKVSRVVHTELNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0X2</accession>
    <name>D3Q0X2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019293.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4070"/>
    <dbReference type="EnsemblBacteria" id="ADD43722">
        <property type="protein sequence ID" value="ADD43722"/>
        <property type="gene ID" value="Snas_4070"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4070"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_11"/>
    <dbReference type="OMA" id="KFYGPID"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040582">
        <property type="entry name" value="OB_MalK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17912">
        <property type="entry name" value="OB_MalK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="360" mass="39023" checksum="54F250AA673A060A" modified="2010-04-20" version="1">MSDLVLRDVRKTYRTKGRPEVEAVRGFDLEVNSGELVGLLGPSGCGKSTTLRMIAGLEDVTGGDIAVGGRSMVGLPPQKRSIGVAFENYALYPPLTVAENIAFGMRARGHRKAERAARVADVAGRIGLSDILDAHPAGLSSGQKQRVALARAVAREPEVLLLDEPLSHLDAAQRDVTRRELRHLQQELGYTTILVTHDQEEALSLADRVVVMNDGVVQQVGTPDVIYDDPVNLFVAQFVGEPAMNILDGRLDDDGVRLSPDLTIPVRTREPRHDRAVTVGVRPEDVTLTGAAEAHATGTVVVYEDLQEYGLATIELPGVDTRVVAQTAPGLTLNPGETQPIAFYSDRTYLFETHTGERLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q142</accession>
    <name>D3Q142_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4141</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019363.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4141"/>
    <dbReference type="EnsemblBacteria" id="ADD43792">
        <property type="protein sequence ID" value="ADD43792"/>
        <property type="gene ID" value="Snas_4141"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4141"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="YEPAHPY"/>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="22"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="58"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="344" mass="37653" checksum="198A3B70E42B351F" modified="2010-04-20" version="1">MTTVEIAKKDVLAGLDPSAPLLRVKNLQVEFNTREGKAKAVNGVNFTLEEGQTLAIVGESGSGKSVTSQAIMGILDIPPARIADGEVLFRGVDLLKLKAKEMRPVRANHIAMVFQDALSALNPVWTVGFQLGELFRIHRGMSRSDARKRAIELLDLVKIPAAKQRVDEYPHQFSGGMRQRVMIAMALALDPEILIADEPTTALDVTVQAQIMRLLAEIQAERQMGLILITHDLGVVADVADDVTVMYAGRAVEQATIHEIFEKPAHPYTKALLKSIPRLDVKGQRLEVIAGLPPVLTNIPPGCSFAPRCGYAQDVCRTDDPELLQFTGERFAACHFSSEVMNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1L6</accession>
    <name>D3Q1L6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0144"/>
    <dbReference type="EnsemblBacteria" id="ADD39864">
        <property type="protein sequence ID" value="ADD39864"/>
        <property type="gene ID" value="Snas_0144"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0144"/>
    <dbReference type="eggNOG" id="ENOG502ZAMQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034353_0_0_11"/>
    <dbReference type="OMA" id="WGINERI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="435" mass="47010" checksum="D92818BCCC9593C5" modified="2010-04-20" version="1">MGNVARLWTGAIAWQAMSGTIIGGRAVPRRLLTVLSLATATAVAAIAVPAIAAETQAMKFEHIDHSPFSLKEGPDGPDYQAMVDKVEADPRVTKSSLSDVVTAASPQRTGRYPLCHDTNLKPELKPTGFCWDSGDDTSADWIPQGVTGSGDADPSGTVDGRRLVAASWHYKEDDFARISIADYTKPAEKLSYHHLLLVQPTADGNFQSVDNVHADGLMWVGDKLFLSTGVRMQVFSLEHIWKTRTDGGDAGKIGLVGDDAYARWHGWAMPMIAEYRTTWSDDGSWKSCNSVTGEQPCMNSIALAPDRKSFVTAEFYQPGAAGGRVIRWGLDEATGLPTGAATEAFVSPIWHQQGIATDGTAFYVVGDCPGSPPPDDPNNHSCIHKALPDDEPHVLTKAPPLTQNLSYWPKTGELWGINERINTSAGKRVVFNVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1M6</accession>
    <name>D3Q1M6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015445.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0154"/>
    <dbReference type="EnsemblBacteria" id="ADD39874">
        <property type="protein sequence ID" value="ADD39874"/>
        <property type="gene ID" value="Snas_0154"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0154"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060397_1_1_11"/>
    <dbReference type="OMA" id="CGPGQWT"/>
    <dbReference type="OrthoDB" id="1865374at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="54"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="23715" checksum="8F3A7460B567D696" modified="2010-04-20" version="1">MSEAPFIAAARAAYDATAEPYAEAVPGKLADMPLDRALFGAFAELMRANQNTTVADVGCGPGHVTDLLCGLGLDAVGIDLSPRMIEVARRRYPKPRFEVGSMLDLDLPDGGLGGVLAFYSIIHLPWTERPRAFAEFHRVLTPGGQLMLGFQIGDERRHHDEAFGKPIDLAWYRQQPGEVAELLRDSGFDVRTTVVTEPEEGQAVRHGHILARKPATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1T6</accession>
    <name>D3Q1T6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dicarboxylate carrier MatC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015505.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0215"/>
    <dbReference type="EnsemblBacteria" id="ADD39934">
        <property type="protein sequence ID" value="ADD39934"/>
        <property type="gene ID" value="Snas_0215"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0215"/>
    <dbReference type="eggNOG" id="COG0471">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052316_1_0_11"/>
    <dbReference type="OMA" id="MVIHGAQ"/>
    <dbReference type="OrthoDB" id="914726at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030676">
        <property type="entry name" value="CitT-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009827">
        <property type="entry name" value="MatC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42826">
        <property type="entry name" value="PTHR42826"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07158">
        <property type="entry name" value="MatC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="MatC_N" evidence="2">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="415" mass="42305" checksum="B87BD56DF79B4FD7" modified="2010-04-20" version="1">MSAELISILVLVAVFAIATTRSVNMGALSFTAAFAVGTLVAGLDAEGIFAGFPGDLFVVLVGVTYLFALARANGTTDWLVHGAVRLVGGRVALIPWMMFAVTGLLTAIGAVSPAAVAIVAPIALGFASRYQISPLLMGVMVVHGAQGGGFSPISVYGAIVNGIVDKEDLPGSPIVLFLASLLVNLVIAAILFVLCGGLKLPRHVAAKDEAADPERDALNPARITTLFALAALVVAVLGFNLDAGLTAITLAAALSVVWPKSSRDAVGQITWPTVLLICGVLTYVAVLEQMGTIDYAGTSVSQIGVPLLGALLICYIGALVSAFASSVGIMGALIPLAIPFLALGDIGAIGMVTALAISSTVVDVSPFSTNGALVLASAAEVDRERFFRQLMIYGGIVVAAVPPIVWLALVVPGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1Y2</accession>
    <name>D3Q1Y2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2156</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2156"/>
    <dbReference type="EnsemblBacteria" id="ADD41849">
        <property type="protein sequence ID" value="ADD41849"/>
        <property type="gene ID" value="Snas_2156"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2156"/>
    <dbReference type="eggNOG" id="COG2351">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000189_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041079">
        <property type="entry name" value="Neuraminidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040840">
        <property type="entry name" value="TcA_TcB_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18413">
        <property type="entry name" value="Neuraminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18276">
        <property type="entry name" value="TcA_TcB_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neuraminidase" evidence="4">
        <location>
            <begin position="1531"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="domain" description="TcA_TcB_BD" evidence="3">
        <location>
            <begin position="2574"/>
            <end position="2850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="217"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2554"/>
            <end position="2588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="3022" mass="332459" checksum="6FED61C7AD2D3328" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q266</accession>
    <name>D3Q266_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Signal recognition particle protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Fifty-four homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ffh</name>
        <name evidence="10" type="ordered locus">Snas_2243</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">The SRP-RNC complex is targeted to the cytoplasmic membrane.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017504.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2243"/>
    <dbReference type="EnsemblBacteria" id="ADD41933">
        <property type="protein sequence ID" value="ADD41933"/>
        <property type="gene ID" value="Snas_2243"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2243"/>
    <dbReference type="eggNOG" id="COG0541">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009301_6_0_11"/>
    <dbReference type="OMA" id="DTAGRHK"/>
    <dbReference type="OrthoDB" id="656414at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004780">
        <property type="entry name" value="SRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="PTHR11564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF7">
        <property type="entry name" value="PTHR11564:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="SSF47446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00959">
        <property type="entry name" value="ffh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54" evidence="9">
        <location>
            <begin position="271"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="433"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="107"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="192"/>
            <end position="196"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="250"/>
            <end position="253"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD41933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="519" mass="55503" checksum="33116B08CDC68607" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2A1</accession>
    <name>D3Q2A1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4184</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4184"/>
    <dbReference type="EnsemblBacteria" id="ADD43834">
        <property type="protein sequence ID" value="ADD43834"/>
        <property type="gene ID" value="Snas_4184"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4184"/>
    <dbReference type="eggNOG" id="ENOG5031XET">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2275716_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021408">
        <property type="entry name" value="DUF3046"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11248">
        <property type="entry name" value="DUF3046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="102" mass="11841" checksum="B6DE62EE5C09B280" modified="2010-04-20" version="1">MRLTEFWENMAETFGRGYAESVAADQTLPQLDGQTINQALSGDWDTKHVWMAVCQAYGERVPSRIRRLAPSRTPVRYSDVRKRHGARRVRHVTGRVYRDRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2L6</accession>
    <name>D3Q2L6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SCP_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021338.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6144"/>
    <dbReference type="EnsemblBacteria" id="ADD45767">
        <property type="protein sequence ID" value="ADD45767"/>
        <property type="gene ID" value="Snas_6144"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6144"/>
    <dbReference type="eggNOG" id="COG3255">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123202_1_0_11"/>
    <dbReference type="OMA" id="ETDAATW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041629">
        <property type="entry name" value="SCP_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17844">
        <property type="entry name" value="SCP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP_3" evidence="1">
        <location>
            <begin position="22"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="115" mass="12315" checksum="C828BEBD07181787" modified="2010-04-20" version="1">MPDAEVIADLMAARERDEPLPRDLLRDGVRALLRELTRKAPGKTVEVRVPPFGAVQCVDGLRHTRGTPPNVVECDAETFVALACGDLDFTAAVADGRVSASGTRADLTDFLPLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2P0</accession>
    <name>D3Q2P0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IIB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6168"/>
    <dbReference type="EnsemblBacteria" id="ADD45791">
        <property type="protein sequence ID" value="ADD45791"/>
        <property type="gene ID" value="Snas_6168"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6168"/>
    <dbReference type="eggNOG" id="COG0561">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044146_0_0_11"/>
    <dbReference type="OMA" id="WFWAYST"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="268" mass="28721" checksum="555C2113BAC5E963" modified="2010-04-20" version="1">MKPRLIATDFDGTLVRSDWTVSGRTNKVLKELSSLGVTIVGITGRGPRLRQLCHRDLPSADFLVLAQGGFVYQVSGVDDVEALHETYIPGADVARAVAIVEREVGPVKVVVENDPTHESTLVGDLIEDWPWPVPMREMSRADALSGHVVKAFIRSDTVEAPRLLRTARELVPAELASLTDAGVGNVEICPPGINKDYGLSLVAKRLGIAASDTIAFGDAENDLSMFAWAGRSIAVANAHDHVKAAADELTASNDDDGVAVYLEKLFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2V1</accession>
    <name>D3Q2V1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Scramblase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6231</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021423.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6231"/>
    <dbReference type="EnsemblBacteria" id="ADD45852">
        <property type="protein sequence ID" value="ADD45852"/>
        <property type="gene ID" value="Snas_6231"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6231"/>
    <dbReference type="eggNOG" id="COG4894">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_943076_0_0_11"/>
    <dbReference type="OMA" id="QIHYQLP"/>
    <dbReference type="OrthoDB" id="1864379at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017128">
        <property type="term" value="F:phospholipid scramblase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018929">
        <property type="entry name" value="DUF2510"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038595">
        <property type="entry name" value="LOR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005552">
        <property type="entry name" value="Scramblase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248">
        <property type="entry name" value="PTHR23248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10708">
        <property type="entry name" value="DUF2510"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03803">
        <property type="entry name" value="Scramblase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="SSF54518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2510" evidence="2">
        <location>
            <begin position="7"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="279" mass="30830" checksum="D8E19BEFF355F5ED" modified="2010-04-20" version="1">MAQNTPPGWYPDPQGSGQQRYWDGNQWTPHLNPGQQQQHQQPSQLEKLAELDVSGPANASQIQQQVQHQAGVQPTQRGGGTLFTEPVLVVNQKTKLIEINNEYSVYDQAGQQLAAVVQVGQSGLKKAIRFLGSYDQFMTHKFEIRDGHGRVLLKATRPAKFVKSRVVIERGDGAPIGEIKQLNAIGKINFGLIVNGQEIGQIRGENWRAWNFAVVDHTGAEVARITKTFEGVLKTMFTTADNYVLQIHRPLQDPMLSMVITSALTIDTALKQDSRGLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2V3</accession>
    <name>D3Q2V3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021425.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6233"/>
    <dbReference type="EnsemblBacteria" id="ADD45854">
        <property type="protein sequence ID" value="ADD45854"/>
        <property type="gene ID" value="Snas_6233"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6233"/>
    <dbReference type="eggNOG" id="COG0412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085632_1_0_11"/>
    <dbReference type="OMA" id="HEYPQAN"/>
    <dbReference type="OrthoDB" id="1200636at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="19749" checksum="ADC85A34C4903A68" modified="2010-04-20" version="1">MSDKRAAVLIPGAWGGQATPWMTYANAAASERGAEVHQIQWEPPQSLYTQPDTVLGWVREHVEPVMDGVDPVASTVVVGKSLGSNAAAIAAERRLPAIWLTPLLTVDRVAEALRGGKAPFLLVGGTADPSWDGKLARELTPHVCEIEGADHGFFRPGEPLARSAEVLALMGTAMETFLDEVVWAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Y6</accession>
    <name>D3Q2Y6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0237</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GroES chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015527.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0237"/>
    <dbReference type="EnsemblBacteria" id="ADD39956">
        <property type="protein sequence ID" value="ADD39956"/>
        <property type="gene ID" value="Snas_0237"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0237"/>
    <dbReference type="eggNOG" id="COG0234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155801_0_0_11"/>
    <dbReference type="OMA" id="MGKRLSW"/>
    <dbReference type="OrthoDB" id="1965002at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD39956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="113" mass="12442" checksum="AFFC384D158EAF2B" modified="2010-04-20" version="1">MLVTAFDTETGLPIRLLHDRVLVRVDTGDGERRSAAGIVIPATASVGHRLAWATAVAVGPLVRMVQTDDRVLFDPDDRSEVELHGREYVLLRERDIHAVAAQRVDDNATGLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Z1</accession>
    <name>D3Q2Z1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NLP/P60 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0243</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="MEROPS" id="C40.007"/>
    <dbReference type="EnsemblBacteria" id="ADD39961">
        <property type="protein sequence ID" value="ADD39961"/>
        <property type="gene ID" value="Snas_0243"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0243"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034085_1_0_11"/>
    <dbReference type="OMA" id="AMPINTI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049665" evidence="4">
        <location>
            <begin position="35"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="5">
        <location>
            <begin position="207"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="38"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="323" mass="34989" checksum="003D89732164DD1A" modified="2010-04-20" version="1">MTTPRSGAAKARRLVSVAVGIALILGFTAVPAEADPSVKELEKKIEKRAEELEGTIEDYNAAREDLDKTKKKIKKLDKKLAPYEKELDKLYDKAEPIVMAAYQGQGLTGPTAMLNSDSPEAFADKISALDGLSAGDAGLIGKVAKKARAYKSKKTDLEELKDEQDKKESDLSKAKKKIEKEIEDLQGDRKTTIKNETGADYVPDYVPGKRGEVVRHAMAQVDKPYVWAAAGPDGYDCSGLILDAYRQIGISLPHNAARQYGQATHIGKGDLQPGDPVFSNGLKHVTMYIGDGYVVHAPTFGQPVQVAKMDTAASPYYGAGTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3A5</accession>
    <name>D3Q3A5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2257"/>
    <dbReference type="EnsemblBacteria" id="ADD41946">
        <property type="protein sequence ID" value="ADD41946"/>
        <property type="gene ID" value="Snas_2257"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2257"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087580_2_1_11"/>
    <dbReference type="OMA" id="KEFHEEY"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="183" mass="20753" checksum="C615B39A537F13F1" modified="2010-04-20" version="1">MHTPAAMRALASPLRREILSHLANHGPATSTTLAKAMGQNTGTTSYHLRMLSDTGFVTELRDRAKGRERWWDVVKGDRRMPPREQLTESEQDLAEQLGDDRLAEDLRLLSAFARDRDEDGDWQQGSRASTFMTKAQLKEFHEEYLKLVRRFGSDRDDAPADARMVLLRWVGFPDPRGSATPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3E9</accession>
    <name>D3Q3E9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41990">
        <property type="protein sequence ID" value="ADD41990"/>
        <property type="gene ID" value="Snas_2301"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2301"/>
    <dbReference type="HOGENOM" id="CLU_210458_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="45" mass="5427" checksum="88C9C1FB588D21E2" modified="2010-04-20" version="1">MSFDYDVANQRVNSMIEDAKAYRLAREARESTPHRRGRRIRLFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3G4</accession>
    <name>D3Q3G4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2318</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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    <dbReference type="OMA" id="HLTWRWA"/>
    <dbReference type="OrthoDB" id="1558246at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EmrB-like"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
    </dbReference>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="21"/>
            <end position="44"/>
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            <begin position="56"/>
            <end position="74"/>
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    </feature>
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        <location>
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            <end position="104"/>
        </location>
    </feature>
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        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
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        <location>
            <begin position="273"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="391"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="403"/>
            <end position="426"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="477"/>
            <end position="495"/>
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    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="22"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ADD42005.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="678" mass="72262" checksum="C1C3707669A05016" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3J7</accession>
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        <recommendedName>
            <fullName evidence="8">PLDc_N domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="9" type="ordered locus">Snas_2352</name>
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        <lineage>
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            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
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    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
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    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2352"/>
    <dbReference type="eggNOG" id="ENOG5031H2X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113604_4_3_11"/>
    <dbReference type="OMA" id="EMLANWE"/>
    <dbReference type="OrthoDB" id="2099951at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="CLS_N"/>
    </dbReference>
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        <property type="entry name" value="PLDc_N"/>
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    </dbReference>
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            <end position="55"/>
        </location>
    </feature>
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            <begin position="14"/>
            <end position="58"/>
        </location>
    </feature>
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            <end position="78"/>
        </location>
    </feature>
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            <begin position="60"/>
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    </feature>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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            <dbReference type="Pfam" id="PF13396"/>
        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3K8</accession>
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        <submittedName>
            <fullName evidence="3">Methionine synthase vitamin-B12 independent</fullName>
        </submittedName>
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        <lineage>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
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                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
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            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ADD42049">
        <property type="protein sequence ID" value="ADD42049"/>
        <property type="gene ID" value="Snas_2364"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2364"/>
    <dbReference type="eggNOG" id="COG0407">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065357_0_0_11"/>
    <dbReference type="OMA" id="DRPGRDT"/>
    <dbReference type="OrthoDB" id="605503at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="49"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="370" mass="38452" checksum="6287117293573828" modified="2010-04-20" version="1">MSEPEAGDRRAEGSRSSDVAPGSRLIVASGADLELGSATASPGVPYGVTTGIGSLPGTDIAEAVRLVLGELPDFPHLPELPHRGPGADMLGRGAALLVDLPVELRVQRWQTARRGGMDLRRSLDFLERDLDTLTDQAAEHDGPIKIAAAGPWTLAASIERPIGGAMLRDPGAVRELTASLTEGLMAHVAQIKARLPHATVILQLDEPSLPGVLAGNIPTESGFSRYRAIEDDEARAALATVIDAVDAPVIVHCCAPDVPVALLASSGAKAVALDLSLIDMDKAESLDPLGEALESGFGLLAGSIPATTAVPSGKAAVEPVLRLWSRLGLPRHRLAELVTVTPACGLAATAPAQVRELLAACREAARRLHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3P0</accession>
    <name>D3Q3P0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemolysin-type calcium-binding region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ADD43957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ADD43957">
        <property type="protein sequence ID" value="ADD43957"/>
        <property type="gene ID" value="Snas_4310"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4310"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_457723_0_0_11"/>
    <dbReference type="OrthoDB" id="1560944at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028208">
        <property type="entry name" value="Effector_pro_NleD-like"/>
    </dbReference>
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        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038332">
        <property type="entry name" value="PPE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
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        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14891">
        <property type="entry name" value="Peptidase_M91"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="357"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="620" mass="66287" checksum="77006308D4C7C566" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Q1</accession>
    <name>D3Q3Q1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4321"/>
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        <property type="gene ID" value="Snas_4321"/>
    </dbReference>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_808690_0_0_11"/>
    <dbReference type="OrthoDB" id="2134147at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="263"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="343" mass="37406" checksum="EBD22299D06EA684" modified="2010-04-20" version="1">MAKPPPGKSSGRGSINDDEGKIEVESGDIPHVTDTEIKDAAEKVRETAVSKGKSERDKAEGDYTIMNPDSMIRPDFASDEEIEEQAKWIPGRFEPYITPNPLDIETLVKRADTIATVFNCSGNNLTDSRLSGAYEIAMTRSDEWEGKAGENFEKYMASLPTIMGNHGKVANMLQIEAQKMIELYKNRRKGAKDIADQAVKAIEAIDDSKGEGLEFLLAVIITIGTFVGLGGGGLAIVGAGVASGATLGGPFLPDDKEELPLGADTIEEVLENMKKALDELDKSITEQEDTLIDAMKFNESEIRPHISDDFGKETLLLPMRPELAGADVKTIKERFHQFTDGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Q2</accession>
    <name>D3Q3Q2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenazine biosynthesis protein PhzF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019540.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43969">
        <property type="protein sequence ID" value="ADD43969"/>
        <property type="gene ID" value="Snas_4322"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4322"/>
    <dbReference type="eggNOG" id="COG0384">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048756_0_0_11"/>
    <dbReference type="OMA" id="CHAWLQA"/>
    <dbReference type="OrthoDB" id="1468060at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
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        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="280" mass="29778" checksum="A77EAECEA3EAD8E8" modified="2010-04-20" version="1">MAGSRDFAQVDVFGQAPYLGNPVAVVLDGDGVEDEVMRRIANWTNLSETTFVLSPNDPEADYRLRIFTPGLELEFAGHPTLGSAHAWLENGGKPKRAGRIVQECAAGLVELRQGEGGLSFAAPPRRRVGELEAEHLAAIVDAFGIEREAVVSHQWVDNGPGWAVIRLGSAEEVLALEPDFSRFPTAMVGAVGEYPKGSEFAYELRTFAPASGVFEDPVCGSMNASVAQWLTGAGEMPAAYKVSQGARLGRRGEVAIAVEEDGTVWVGGATTTCFRGTAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3V6</accession>
    <name>D3Q3V6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44023">
        <property type="protein sequence ID" value="ADD44023"/>
        <property type="gene ID" value="Snas_4376"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4376"/>
    <dbReference type="HOGENOM" id="CLU_3222359_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048849" evidence="1">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="44" mass="4459" checksum="52B67C78E75B5587" modified="2010-04-20" version="1">MLVALCCAVVVIAVVVLVVVLVTRKKDQQPPPPPGGWSGPAPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q437</accession>
    <name>D3Q437_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IIA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021493.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6302"/>
    <dbReference type="EnsemblBacteria" id="ADD45922">
        <property type="protein sequence ID" value="ADD45922"/>
        <property type="gene ID" value="Snas_6302"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6302"/>
    <dbReference type="eggNOG" id="COG0647">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043473_1_1_11"/>
    <dbReference type="OMA" id="MDGVLIH"/>
    <dbReference type="OrthoDB" id="1308416at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="261" mass="27625" checksum="EFF798156146FE55" modified="2010-04-20" version="1">MHERGPIECWLSDMDGVLVHEGIPVPGADRFITALAESGKTFLVLTNNSKYTPRDLHFRLKAAGLDVPADSIYTSANATADFLSTQRPGGSAYVIGEAGLTTALHEIGYVLTDIDPDYVVLGETSAYSFGAITTAIRLVEGGARFIATNPDASGPSVEGILPATGAVAALITKATKVEPYFVGKPNPLMMRSALNKAGGHSESTAMIGDRMDTDIVSGMEAGLETILVLSGLTSREEIARYPYQPLRVVESVADLIPLIND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4B9</accession>
    <name>D3Q4B9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Clp domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0361</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0361"/>
    <dbReference type="EnsemblBacteria" id="ADD40079">
        <property type="protein sequence ID" value="ADD40079"/>
        <property type="gene ID" value="Snas_0361"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0361"/>
    <dbReference type="eggNOG" id="COG0542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_364805_0_0_11"/>
    <dbReference type="OMA" id="MAGRIMD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="6">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="495"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="500"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="765" mass="84723" checksum="3B1A3848C861C788" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4C4</accession>
    <name>D3Q4C4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Adenylosuccinate synthetase</fullName>
            <shortName evidence="8">AMPSase</shortName>
            <shortName evidence="8">AdSS</shortName>
            <ecNumber evidence="8 10">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">purA</name>
        <name evidence="11" type="ordered locus">Snas_0367</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="8 10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015655.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0367"/>
    <dbReference type="EnsemblBacteria" id="ADD40084">
        <property type="protein sequence ID" value="ADD40084"/>
        <property type="gene ID" value="Snas_0367"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0367"/>
    <dbReference type="eggNOG" id="COG0104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029848_0_0_11"/>
    <dbReference type="OMA" id="FHHAKPI"/>
    <dbReference type="OrthoDB" id="232152at2"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="2 8 10" id="KW-0436">Ligase</keyword>
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    <keyword evidence="3 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
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        </location>
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        <location>
            <begin position="299"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="140"/>
        </location>
    </feature>
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        <location>
            <begin position="12"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="40"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
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        </location>
        <ligand>
            <name>Mg(2+)</name>
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        </ligand>
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    <feature type="binding site" evidence="8">
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            <position position="129"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
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        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
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        <ligand>
            <name>IMP</name>
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            <name>IMP</name>
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            <name>IMP</name>
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        </ligand>
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        <location>
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        </location>
        <ligand>
            <name>GTP</name>
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        </ligand>
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        <location>
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            <end position="415"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD40084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="428" mass="46512" checksum="7BCBA8C5F2C6A1D2" modified="2010-04-20" version="1">MPATVVIGTQWGDEGKGKATDLLGEHMDYVVRYQGGNNAGHTVVTPDGEKFAIHLCPVGILTPGCVPVIGNGVVVDPKFLLHELDGLAARGVDVSNLRLSSDAHLVMPHHRALDRVVERYLGSARIGTTGRGIGPAYGDKVGRVGIRVQDLLDPGILKQKLEMVLREKNQVLVKVYNRKAIDVQTVVDEYLGYADRLAPYIADTRLELDKALTAGKNVLLEGAQATMLDVDHGTYPFVTSSNPTTGGACMGSGIPPTRIDKVIGIIKAYTTRVGAGPFPTELFDENGAHLLKVGGEYGVTTGRERRCGWFDAVIGRYAVRVNGITDLFLTKADVLSSLPKVPICVGYDIDGEFHEEMPMSQTALHHATPRYEYHDGWWEDISECREFSDLPKNAQSYIERLEELCGARISVIGVGPGRSQNIVRSALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4E8</accession>
    <name>D3Q4E8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M14 carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0391</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ADD40108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0391"/>
    <dbReference type="EnsemblBacteria" id="ADD40108">
        <property type="protein sequence ID" value="ADD40108"/>
        <property type="gene ID" value="Snas_0391"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG2866">
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    <dbReference type="OMA" id="YGQDSAF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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    </dbReference>
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        <property type="entry name" value="Peptidase_M14"/>
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        <property type="entry name" value="Zn_pept"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048230" evidence="2">
        <location>
            <begin position="31"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M14" evidence="3">
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            <begin position="117"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="277"/>
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        </location>
    </feature>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
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            <dbReference type="SMART" id="SM00631"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="ADD40108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="446" mass="48003" checksum="FCE7B0896619FB83" modified="2010-04-20" version="1">MKTRRKLISLLSAAAVVAAGTGLIVGSANADPGSDRNPGEQVAWKVPGLTGKQATSLEDDGFDLVDYEDDGSAIVIGDEKVADKLRDKGMKPKFLDTIVKPVDKDYKDTADTYYGGYHTVTAHEEHLDKVASEHSDLAKVYDIGDSWLKTKGEGGHDIKAICITKIADGDCEQKPDSKKPRFSMIAQMHAREIATGEVAWKFIDKLTTGYGQDDAVTKLLDSTEVWVVPIANPDGVDIVASGGDNPILQRKNANDSAGDCGESKGVDLNRNSSFKWGDDSDDPCAETYQGTAAKSEPETAGLEEWFQNIHPDQREDDPSSPAPNDARDTMITLHSYGQYIIIPWGFTEDQSPNDAQLRALGEKMSESNGYKVGTNGDTVGYSTSGTTDDFTYGQLGVASFTFEMGADSGDCGGFLPVYECVDSTLWKENEGALMTAAEAAKAPYAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4H0</accession>
    <name>D3Q4H0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0413</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
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            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40130">
        <property type="protein sequence ID" value="ADD40130"/>
        <property type="gene ID" value="Snas_0413"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0413"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="NEIAYTE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTH_LacI"/>
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    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="358" mass="38540" checksum="5CF4DC35F749B145" modified="2010-04-20" version="1">MASGGRVGITDVAKRAGVSVTTVSHVLSSRRPVAEATRQKVLRVIEELDYRPNEVARSMRVQRTSTVGLVVPNISHPFYTAAARGLEDALRPEGYHCIVTSTDADRDVERDAVRQLLSRVDGFVISGADKRTEDIQPILDAKLPLVMLGADIPGPGFDVVTNADFESGSLAAQHMLERGHRRIAFITAEDDFAAGARRVEGYRSALDKAGLSTEASLVIRAAASLEGGAKALANLRKLAEPPDAVICVSDVMAIGAMYAAREAGLRIPEDVAVMGFDDTEAAALVAPPLTTMATASRDHGRKAGELILRRIQDGTADVEPQRVVFPAKLIQRESTLGRWRGLLRVLPGRERRLLARLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4M5</accession>
    <name>D3Q4M5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylmethionine-8-amino-7-oxononanoate aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.62</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">7,8-diamino-pelargonic acid aminotransferase</fullName>
            <shortName evidence="4">DAPA AT</shortName>
            <shortName evidence="4">DAPA aminotransferase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">7,8-diaminononanoate synthase</fullName>
            <shortName evidence="4">DANS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Diaminopelargonic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bioA</name>
        <name evidence="6" type="ordered locus">Snas_0470</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(8S)-8-amino-7-oxononanoate + S-adenosyl-L-methionine = (7R,8S)-7,8-diammoniononanoate + S-adenosyl-4-methylsulfanyl-2-oxobutanoate</text>
            <dbReference type="Rhea" id="RHEA:16861"/>
            <dbReference type="ChEBI" id="CHEBI:16490"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="EC" id="2.6.1.62"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; biotin biosynthesis; 7,8-diaminononanoate from 8-amino-7-oxononanoate (SAM route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.62" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015756.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0470"/>
    <dbReference type="EnsemblBacteria" id="ADD40185">
        <property type="protein sequence ID" value="ADD40185"/>
        <property type="gene ID" value="Snas_0470"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0470"/>
    <dbReference type="eggNOG" id="COG0161">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_4_3_11"/>
    <dbReference type="OMA" id="ARRHVFE"/>
    <dbReference type="OrthoDB" id="478143at2"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00834">
        <property type="entry name" value="BioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005815">
        <property type="entry name" value="BioA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00508">
        <property type="entry name" value="bioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="121"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="322"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM" evidence="4">
        <location>
            <position position="21"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="442" mass="48200" checksum="B1705702F1183FFA" modified="2010-04-20" version="1">MGETESERWRRRDAAAVWHPFTQHSLWLDDEPTVVDRAEGPWLYDVDGNRYLDGVSSLWVTTFGHREPRIDAAIRDQLDRLDHATFLGATHPVGIELAERLLAVAPRGDRELSKVFYAGDGSSAVEVALKMAYQYSTQTNGPRPQFIRLSQAYHGDTLGAVSVGGVELFHDTYRPLLLKTLELGSPGVRRPGQSAAERAAESIEELKRLLAEHGDQVCALIVEPLVQGAAGMLTHHPDFLRAARELTDAHGVLLICDEVATGVGRTGRMWASQHADVVPDLLVTAKGITGGYLPLSAVLTTQAVYDAFLGAPARARTFFHGHTYTGSPLAAAAALANLRLMAETNLVDRAARLGDRLGARLAPLAEHPGVVEIRRLGTMTGVEVRPRGERTGVRVCRFARNRGVWIRPLGDTVILMPPLGLEDTQVDMLVDALAGALDEVYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Q2</accession>
    <name>D3Q4Q2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sodium/hydrogen exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2399</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2399"/>
    <dbReference type="EnsemblBacteria" id="ADD42082">
        <property type="protein sequence ID" value="ADD42082"/>
        <property type="gene ID" value="Snas_2399"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2399"/>
    <dbReference type="eggNOG" id="COG3263">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005912_9_1_11"/>
    <dbReference type="OMA" id="WFDEYGE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005451">
        <property type="term" value="F:monovalent cation:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030151">
        <property type="entry name" value="NhaP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32507:SF7">
        <property type="entry name" value="PTHR32507:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="356"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="5">
        <location>
            <begin position="398"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="530" mass="55958" checksum="03394C3B6EBD32DC" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4V0</accession>
    <name>D3Q4V0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SUF system FeS assembly protein, NifU family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2447"/>
    <dbReference type="EnsemblBacteria" id="ADD42130">
        <property type="protein sequence ID" value="ADD42130"/>
        <property type="gene ID" value="Snas_2447"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2447"/>
    <dbReference type="eggNOG" id="COG0822">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079283_4_0_11"/>
    <dbReference type="OMA" id="MKLDSMY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="PTHR10093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="1">
        <location>
            <begin position="6"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="156" mass="16843" checksum="102292C8CDF6FA97" modified="2010-04-20" version="1">MLDELYQEVILDHYRSPHGKGLREPFEGETHHVNPTCGDEITLRVHLDGDTVADVSYDSVGCSISQASASVLYDLVNGKSVDQAMFALDEFSRLMTGKGETEPDEDVLEDAVAFAGVSKFPARVKCALLSWMAFKDAAIRAGAKTTAEATSGEAND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q541</accession>
    <name>D3Q541_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4445"/>
    <dbReference type="EnsemblBacteria" id="ADD44090">
        <property type="protein sequence ID" value="ADD44090"/>
        <property type="gene ID" value="Snas_4445"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4445"/>
    <dbReference type="HOGENOM" id="CLU_658737_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="417" mass="42311" checksum="776DA82F837F0963" modified="2010-04-20" version="1">MRRRRFQQILVGRHGLHTGVRLIRRHVLEVTRGLVTFPETTTVPVITIAEPTTTTVVPVAEAAASAIITVAETATTTVIAVLEATTVVAATEATALAVTVPTEPTALTVITSSKAATLTVIAATEPALATVVASVPAESATVVSALEAAALAVIPSTESAALTVVTSPETATLAIIAASKATTLTVIAATEPATLAIIPTPEAPTIIATTETTRRTVTTVITARAVPVVAEAAALTVIASPEATALAVVTAPETATLAIVTSSKATALTVITPAETPTITVTTPEPATLTVITTPKATALAVITTVTAAETSTVVTTLETATLAVTIPTEATTTAVITIPGTPETPTIPVIAEPTAIIATTTPVVTTVTALVPAVLAAAMRIVARPLRPIGIRFRHDAQSSPAATRYFRRTAVKFQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5F4</accession>
    <name>D3Q5F4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6398</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021585.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6398"/>
    <dbReference type="EnsemblBacteria" id="ADD46014">
        <property type="protein sequence ID" value="ADD46014"/>
        <property type="gene ID" value="Snas_6398"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6398"/>
    <dbReference type="eggNOG" id="COG4122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062591_0_0_11"/>
    <dbReference type="OMA" id="FRHGGFE"/>
    <dbReference type="OrthoDB" id="1244860at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD46014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="264" mass="28919" checksum="2449556A7E6DA583" modified="2010-04-20" version="1">MRPRPRGTVTRGTTNPNRLRRLDRWLAATAASRLRAATDPLVVDLGYGATPVTTLEWYRRLRRVRPDVRIVGLEIDPARVAAASELAVDGRVEFALGGFELAGLRPVLVRAANVLRQYPETEVPQAWQLLRQALAPGGLIVDATCDELGRVATWISLDASGPTTLTLAASLPYLESPAILAERLPKALIHHNVPGQRIHTLVAALDAAWRDAAPARVFGPRDRWRRTLDTLAATGWPVAEPPARRRDGTLTLPWHLVTPEPSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q699</accession>
    <name>D3Q699_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017845.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2595"/>
    <dbReference type="EnsemblBacteria" id="ADD42274">
        <property type="protein sequence ID" value="ADD42274"/>
        <property type="gene ID" value="Snas_2595"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2595"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_11"/>
    <dbReference type="OMA" id="VWDTTMA"/>
    <dbReference type="OrthoDB" id="1294334at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="257" mass="26263" checksum="D9A2835641204806" modified="2010-04-20" version="1">MSDYLRSLFNLDGKVALITGGSSGIGFGITEALARAGAAVVLVARTQSGLDDAVAALTKVGGRAAAISADLSSRADVARVCDTAADHFGEPDILVCAAGVNPRPPLAELTTEDWDLALEVNTTAPFLLGQRFGSRMAERGYGRIINIASQQAVRAFGNSGGYGVSKAAICGLTRSQAEAWSASGVCCNAISPAFVHTPLTAAAVAIPGRSEQMAARTMIGRNSQPEDFAGMAVFLAGPASSYVTGQTLFVDGGFSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6C4</accession>
    <name>D3Q6C4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2621</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017870.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2621"/>
    <dbReference type="EnsemblBacteria" id="ADD42299">
        <property type="protein sequence ID" value="ADD42299"/>
        <property type="gene ID" value="Snas_2621"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2621"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_8_0_11"/>
    <dbReference type="OMA" id="GKAYMFF"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="91"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="320" mass="34287" checksum="1BD0D3AD0EBC4E66" modified="2010-04-20" version="1">MTTPTVTAPGDAERRAANRLLFFRNRKTLIGLGILGFFVVMAIVGEWIAPYDPSKTSPDVLQPPSAQHWLGTTNTGQDIASQLLVGTRGVLLVGLLAGLAATVLSVIVGVTAGFLGGVGDEILSLVANIFLVIPALPLIIIVAGLLPEAGGITVAVVISLTGWAWGSRVLRAQTLSLRRRDFVEAARANGESMWRLVIFEILPNLTAVIAAGFVGTVIFAILSEIALAFIGVTSISEWNWGTILFWAQSNQALAQGAWWWFVPAGLCIAGVGTALTLINFGIDEFVNPRLRTTGRDAKLLRAKRIRARVGFTPVLRQEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6U6</accession>
    <name>D3Q6U6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0631"/>
    <dbReference type="EnsemblBacteria" id="ADD40345">
        <property type="protein sequence ID" value="ADD40345"/>
        <property type="gene ID" value="Snas_0631"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0631"/>
    <dbReference type="eggNOG" id="ENOG502ZRMN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131550_3_0_11"/>
    <dbReference type="OMA" id="TNKIVWR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="1">
        <location>
            <begin position="16"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="72" mass="7773" checksum="36605BCC5AFFAFA8" modified="2010-04-20" version="1">MPVLRTLDATTRAAIAWRKSSRSPSNGGNCVEVGARPHHGIAVRDSKHPTVTPLTITRSDWTALLRTVKANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6V3</accession>
    <name>D3Q6V3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015923.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0639"/>
    <dbReference type="EnsemblBacteria" id="ADD40352">
        <property type="protein sequence ID" value="ADD40352"/>
        <property type="gene ID" value="Snas_0639"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0639"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042397_0_0_11"/>
    <dbReference type="OMA" id="QWELESA"/>
    <dbReference type="OrthoDB" id="897911at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="468" mass="48684" checksum="B55CB8F7BBEE9971" modified="2010-04-20" version="1">MVTYSQLVNMDTSKLSGAAEAAGGLSSTLSTRAGEVQTSAQIPGGMWAGVDASAASGLLETQPSPLFDASDVFRSSRAALEDLVVDLEAAKTKLTDAQDLVAGTGITIGPDGTVTTPVVESATAADRNAQLAQQARELIDEALKLADHADQTAVSTLTTAGLRMNAPDFAGPTDPGIAAAQAEAFRKTLGRLPMSETDWQLAAALDPTSRLDKNGGQDAVVAVGRITPRPGEGLVRIGLYIPSSEVFNLPNYDKGDNRGMNPNFSPEDTRVTLYVDYETGTVLARQNPSVDTSGEVRVGTPEVQVQESTNGAVRIQYDAANPFAPPGSDVTGHSVKGDITVTPGTGDDAPRIDGTIGDYPAFEAYHDTNDGPTTTIIQDPADNEGTFGPLIELPTNHEIGAGQGPATQFQQWRPLSGEYWQVDPTAPPAPSIDLGDPANPPKATPYEPFGGDSVHPDVPGVPSGGPMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q743</accession>
    <name>D3Q743_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0730"/>
    <dbReference type="EnsemblBacteria" id="ADD40442">
        <property type="protein sequence ID" value="ADD40442"/>
        <property type="gene ID" value="Snas_0730"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0730"/>
    <dbReference type="eggNOG" id="ENOG502ZAHT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097505_0_0_11"/>
    <dbReference type="OMA" id="AWCVRLV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="192" mass="21892" checksum="58535FC297ADA0C6" modified="2010-04-20" version="1">MNLWQVCMHPKDNTASWRYADVPQADDAASWIAGRVPDDWFVSLPEVSADRDELIIIGHLEEPEHESDATEADRAAAEEGRISRFREATRDQRVQISQQIQHRYQRRASWGAACGSTRIVFTHQTIPVMSRLRQPERRVLDTLVDSGVARSRSDALAWCVRLVGEHADSWLMELRSAMSSVDELRRKGPDIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q745</accession>
    <name>D3Q745_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2639</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017887.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2639"/>
    <dbReference type="EnsemblBacteria" id="ADD42316">
        <property type="protein sequence ID" value="ADD42316"/>
        <property type="gene ID" value="Snas_2639"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2639"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="FYLFTQY"/>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="16"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="503"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="529" mass="54727" checksum="3ACF668B70D5CB4C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7H4</accession>
    <name>D3Q7H4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019887.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4673"/>
    <dbReference type="EnsemblBacteria" id="ADD44316">
        <property type="protein sequence ID" value="ADD44316"/>
        <property type="gene ID" value="Snas_4673"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4673"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_2_0_11"/>
    <dbReference type="OMA" id="HNRSAAR"/>
    <dbReference type="OrthoDB" id="1748559at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="3"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="145" mass="15495" checksum="E27CCB8957F4D7C6" modified="2010-04-20" version="1">MAGMRVGQVAEAAGVNRETLRYYERRGIIAEPGRTVGGHRLYPPETVTVLRVIKAAQRLGFTLAEVEDLLAVGVRRHGRRRDVGLRERATVKLGEVERRIADLTVIAGTLRRAIAAGCDDLVECAGNECCPIPFAGLGSGTSAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7K6</accession>
    <name>D3Q7K6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gas vesicle synthesis GvpLGvpF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4705</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May play a structural or regulatory role in gas vesicle synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Vacuole</location>
            <location evidence="2">Gas vesicle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Vesicle</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4705"/>
    <dbReference type="EnsemblBacteria" id="ADD44348">
        <property type="protein sequence ID" value="ADD44348"/>
        <property type="gene ID" value="Snas_4705"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4705"/>
    <dbReference type="eggNOG" id="COG2214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065736_3_1_11"/>
    <dbReference type="OMA" id="NGPWAPH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031411">
        <property type="term" value="C:gas vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031412">
        <property type="term" value="P:gas vesicle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009430">
        <property type="entry name" value="Gas-vesicle_GvpL/GvpF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36852">
        <property type="entry name" value="PTHR36852"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06386">
        <property type="entry name" value="GvpL_GvpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0304">Gas vesicle</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="256" mass="27499" checksum="650FAAA6DEAC09ED" modified="2010-04-20" version="1">MTASPALTTVCFVYGIVPAETELDPELLGVGDPASQVSLVRSGDIAAAVSQIPADEPLGSYRDLQAHAQVLDRLAEDGPVLPMRFGAAMADEDAVAGELLANSHDDFHRSLENLRGLTQFLVKGSYESTAVLTEVVTEDPATSSLREAIRDKPPELTQPEQIELGKAIASALAQRRSADTEVLLARLAPLGAEFNVREPNGEYVAFRVAVLLHQERTGELGDILDDLSSEWEGRLNLRLVGPMAPYDFVPTPTNGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7L1</accession>
    <name>D3Q7L1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019924.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4710"/>
    <dbReference type="EnsemblBacteria" id="ADD44353">
        <property type="protein sequence ID" value="ADD44353"/>
        <property type="gene ID" value="Snas_4710"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4710"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_927220_0_0_11"/>
    <dbReference type="OMA" id="WPRNFLR"/>
    <dbReference type="OrthoDB" id="1518440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="76"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="265" mass="28611" checksum="EF9CFCA8EF1640BE" modified="2010-04-20" version="1">MSQSIPDPQQLRSYMYGEGDLGGLTLFSGGFINYGYWPDTIDTSGELTQAERTRSQAELYRQVVARLDGARDGRLLEIGCGKGAGASLVASEYFPAFVVGLDLSAQQLARAAAAKPPPPLKLVRASALSLPVGTSTLDGVYCVEAAQHVDDHRRLAVEAHRVLRAGGRFVLAGFFAPGGEPEPRLAELLETVGNGIDVVAPVSGFAEHLAEAGFGDIVTESIGERVWEGMDAWIAQTEYHDSWGRNWLPAYRDGWVDYYLIHATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7L2</accession>
    <name>D3Q7L2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019925.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4711"/>
    <dbReference type="EnsemblBacteria" id="ADD44354">
        <property type="protein sequence ID" value="ADD44354"/>
        <property type="gene ID" value="Snas_4711"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4711"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081534_4_0_11"/>
    <dbReference type="OMA" id="NVNLFWV"/>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="25"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="176" mass="19416" checksum="AF5129DF61F1882F" modified="2010-04-20" version="1">MTSQASTRLRWAVDTLSPAPDDRLLEVGCGHGVAVTLVSQRLDTGTVIGIDRSEKMIAAATRRNRSHVDNDTAFLLRTEFPDTGLEPEFDTIFAAHVNVFWKRPVTALAEVRRLLRPGGRLYLFWQAPSWEPGFDKRGFAEPIAATLREHGLIDDEIIIGPPGDSDDSFCITAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7R2</accession>
    <name>D3Q7R2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Daunorubicin resistance ABC transporter ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4762</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4762"/>
    <dbReference type="EnsemblBacteria" id="ADD44404">
        <property type="protein sequence ID" value="ADD44404"/>
        <property type="gene ID" value="Snas_4762"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4762"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="ASHMLSE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="18"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="309" mass="33393" checksum="77D00E6AD531848D" modified="2010-04-20" version="1">MAYAERMAYTLMESDAAVELRRLRKSYGANLVIDEVDLTVPAGSVFALLGPNGAGKTTIVNVLSTLIPFDGGSATVMGHDVRSEPARVRREIAVTGQFAAVDELLTGRENLTMFARLNRVPRARLRSRVDAMLDGFDLAQAADRRVRGYSGGMKRRLDLAISMLIRPRVLFLDEPTTGLDPRSRAAVWEFVRELARDGVTILLTTQYLDEADQLADGLALLDGGRIVAEGSPADLKRRVGTEIVHIEYSDGRSLNLPTDGSFAGIREAMLGVDGADLVAAVEIRTPSLDDVFFTLTGQAAARQSEGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7T1</accession>
    <name>D3Q7T1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Peptidase M4 thermolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Snas_4782</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4782"/>
    <dbReference type="EnsemblBacteria" id="ADD44423">
        <property type="protein sequence ID" value="ADD44423"/>
        <property type="gene ID" value="Snas_4782"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4782"/>
    <dbReference type="eggNOG" id="COG3227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008590_5_1_11"/>
    <dbReference type="OMA" id="WKHIKLT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023612">
        <property type="entry name" value="Peptidase_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001570">
        <property type="entry name" value="Peptidase_M4_C_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013856">
        <property type="entry name" value="Peptidase_M4_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01447">
        <property type="entry name" value="Peptidase_M4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02868">
        <property type="entry name" value="Peptidase_M4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00730">
        <property type="entry name" value="THERMOLYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048724" evidence="9">
        <location>
            <begin position="29"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="domain" description="FTP" evidence="12">
        <location>
            <begin position="74"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4" evidence="10">
        <location>
            <begin position="195"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4_C" evidence="11">
        <location>
            <begin position="342"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR623612-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD44423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="802" mass="82153" checksum="7A3DDC308CBC338F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7X0</accession>
    <name>D3Q7X0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyprenyl synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0763"/>
    <dbReference type="EnsemblBacteria" id="ADD40475">
        <property type="protein sequence ID" value="ADD40475"/>
        <property type="gene ID" value="Snas_0763"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0763"/>
    <dbReference type="eggNOG" id="COG0142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_2_1_11"/>
    <dbReference type="OMA" id="GWWDEHG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="346" mass="36521" checksum="5E8381E696D1EDE2" modified="2010-04-20" version="1">MDTIDVIPGSRSAREILSHSRTLVDPGLRAAVDTLPPPTRHIAGYHFGWWDENAEPAEHKAGKAIRPALVLLCARAVGSSDIEALPAAVAVELVHNFSLVHDDVIDRDVTRRHRPTAWSVFGDGAAILAGDAMSTLACAVLADSGHPAAMDGIKLVNRAIQELIDGQHADVSFETREQIDPQECRAMAAAKTGALLGCACAIGARFGGGSPHQVERLRAFGTDLGLAFQHVDDLLGIWGDPQATGKPVYSDLRSRKKSLPVVAALASDSPAAAALSSLYSGTEPLRDEEITRAAALIEEAGGRQWSSTEAAGLLDRALASLAEVGAEESAASDLTTLARLVTRRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q855</accession>
    <name>D3Q855_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0849</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016131.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0849"/>
    <dbReference type="EnsemblBacteria" id="ADD40560">
        <property type="protein sequence ID" value="ADD40560"/>
        <property type="gene ID" value="Snas_0849"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0849"/>
    <dbReference type="eggNOG" id="COG4991">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134974_0_0_11"/>
    <dbReference type="OrthoDB" id="1663368at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048740" evidence="2">
        <location>
            <begin position="32"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="179" mass="18657" checksum="132670C9537FF9D0" modified="2010-04-20" version="1">MKKKAVTRLVIGAAAAIAALALAFVPALASAESPATTVDQQEQSQKSPADGTPQGAIEWYQEREGSSEYEGMCEMAAENAYGTTGVWPSAIDHWNATNEAGTAHPGDTNPPLGAFVFWNTSEYGHVGVADGNGGFWASSVGGAIGHSDDLGYYGDVYLGWSDPQVPAGKGELPEGTRQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8C9</accession>
    <name>D3Q8C9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018074.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2827"/>
    <dbReference type="EnsemblBacteria" id="ADD42503">
        <property type="protein sequence ID" value="ADD42503"/>
        <property type="gene ID" value="Snas_2827"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2827"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_25_3_11"/>
    <dbReference type="OMA" id="ADRAEIM"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16859">
        <property type="entry name" value="TetR_C_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="186" mass="19892" checksum="51205E3370B541E3" modified="2010-04-20" version="1">MTRAAASARPPGRPRNSVDATVFAATLSTVDELGYARATVDRIAAAAGIAKTTIYRRWPTKGALITACLIEAFGPLPMTATTREDFLAESIRFAAAKIAEPGVGAAFAGVFTDAVNDPALREILATQLQEPYLIAIREVLGEPEHRVLFLIDVIIGTLLHRMGMTGEPMVDDDVDALVAMTLRVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8S8</accession>
    <name>D3Q8S8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ANTAR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4879</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4879"/>
    <dbReference type="EnsemblBacteria" id="ADD44520">
        <property type="protein sequence ID" value="ADD44520"/>
        <property type="gene ID" value="Snas_4879"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4879"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074354_1_0_11"/>
    <dbReference type="OMA" id="FVRLRAY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005561">
        <property type="entry name" value="ANTAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03861">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01012">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50921">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ANTAR" evidence="3">
        <location>
            <begin position="157"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="230" mass="24604" checksum="DF607B061DBF2BB9" modified="2010-04-20" version="1">MPEPDRDRILSALSGSNTAAERLSEVCLELLPGLDGASITVIGNPAAHATVSTAGDDVGMTDLQFTLGEGPYVDAHNDRRPVLASDLSEPGYRVRWPAFTPASLAAGVHAVFALPLRIGAIHVGVLNLHRREPGELGVIELSDAFAFAEAVTLLVLGHSASGEDQAPQLRVQHRVALHQATGIIMAQLGVSVEEAFVRLRAYTYVDGRTLDEVAVDVVARRIRFDVEEQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8V2</accession>
    <name>D3Q8V2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020115.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4903"/>
    <dbReference type="EnsemblBacteria" id="ADD44544">
        <property type="protein sequence ID" value="ADD44544"/>
        <property type="gene ID" value="Snas_4903"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4903"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_425723_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048321" evidence="2">
        <location>
            <begin position="25"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="643" mass="68053" checksum="1C27B2D5CB50B24E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8X4</accession>
    <name>D3Q8X4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0872</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016154.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0872"/>
    <dbReference type="EnsemblBacteria" id="ADD40583">
        <property type="protein sequence ID" value="ADD40583"/>
        <property type="gene ID" value="Snas_0872"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0872"/>
    <dbReference type="eggNOG" id="COG3177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058793_1_0_11"/>
    <dbReference type="OMA" id="VDRVYGH"/>
    <dbReference type="OrthoDB" id="1374721at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="247" mass="25936" checksum="80FDFFB98725B5FC" modified="2010-04-20" version="1">MVSRVSDPLSPLLELAEVADSLENARAAVDRTLWHRRLRREGAQVATEVSLRCAVASATLDGAEYPIEEVRAGTVTDPVVQGALRVSTELPSLVTLWPKAPRQVLAKLHLLAARDLADVDQLGRPDADPHKAARLDALCALITAESRLPAALVAAVVHGELLALRPFPQAAGVVARAAARLTLAARGLDPNLLIAIDAGHAGRGPEYTGASGTFATGTPDGLRSWLKHCGLALSLGAEITTEICNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q964</accession>
    <name>D3Q964_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0963</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40673">
        <property type="protein sequence ID" value="ADD40673"/>
        <property type="gene ID" value="Snas_0963"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0963"/>
    <dbReference type="eggNOG" id="ENOG502ZPIZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1224221_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="259" mass="29682" checksum="B06A64717F530167" modified="2010-04-20" version="1">MFGQPGLLQPAGPAQSDWLVHFCGRPPGTRKSPCLPEDIDDLTAEERLESILWEERVRGFATFSRLDGPRMVCFSEAPLLHLNWFFQDKKWPQWGLIFSRQQVYDVGGGPVWHLRGTEIDRLNPELRHWAVRLEVGPARRSDWLHEREWRIPLPDGSEAISLTTFTPDRSEESLPLALKLEAILIATADWQPSERWEDVETGHFLNEGGGGYVTPDYHGAIPETISAPLLPILWEKTVRVMWDFDRKTFVKVDDTGHAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9L0</accession>
    <name>D3Q9L0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase associated with various cellular activities AAA_3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4915"/>
    <dbReference type="EnsemblBacteria" id="ADD44556">
        <property type="protein sequence ID" value="ADD44556"/>
        <property type="gene ID" value="Snas_4915"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4915"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034716_2_0_11"/>
    <dbReference type="OMA" id="FMARVSI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="56"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="249"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="335" mass="36370" checksum="FE242277C6C5ED75" modified="2010-04-20" version="1">MSAQPIGTTSPAAAQPMSSTEFKAAVDAVIGNIERVIEGKTAIVRLAFSVLLAEGHLLIEDVPGVGKTMLAKSMATTIHCSVRRIQFTPDLLPSDVTGVTIFNQDTHEFTFKPGAVFANLVVGDEINRASPKTQSALLECMEERQVTVDGNTYKLRAPFMVMATQNPIEMEGTYPLPEAQRDRFTARIAIGYPDAAAELKMLDVHGTTNPLNQLQPVVDEATIQRMIEYVRGIHVSDAIKQYAIALVNATRQAPELRLGASPRSVLQLLRTARAIAAFEGRDFVLPDDVQALSVPVLAHRLLPTSDAQLAHRTTDAIISDIVHRLPVAPGAPIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA11</accession>
    <name>D3QA11_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 8">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glmS</name>
        <name evidence="11" type="ordered locus">Snas_1013</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016294.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1013"/>
    <dbReference type="EnsemblBacteria" id="ADD40723">
        <property type="protein sequence ID" value="ADD40723"/>
        <property type="gene ID" value="Snas_1013"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1013"/>
    <dbReference type="eggNOG" id="COG0449">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012520_5_2_11"/>
    <dbReference type="OMA" id="ASEYRYA"/>
    <dbReference type="OrthoDB" id="43416at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="289"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="461"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GATase activity" evidence="8">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="For Fru-6P isomerization activity" evidence="8">
        <location>
            <position position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD40723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="616" mass="65925" checksum="19AC654237AAD80D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAA3</accession>
    <name>D3QAA3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1105</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016386.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1105"/>
    <dbReference type="EnsemblBacteria" id="ADD40815">
        <property type="protein sequence ID" value="ADD40815"/>
        <property type="gene ID" value="Snas_1105"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1105"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_5_2_11"/>
    <dbReference type="OMA" id="FKGLDPM"/>
    <dbReference type="OrthoDB" id="1425840at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="13"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="150"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="334" mass="34493" checksum="C13482C83108BE7A" modified="2010-04-20" version="1">MGSGMAAVRVGVLALLWGSTYLWIKLALTGLTPTQVTFARCLLGAAVLVVLCAAGRQRLPRDRGTWLRILVAAFFCNALPYALFSIGQQTVDSGVAGVLNATTPLWTLVVGIAIGAERRPHPVRVGGLLLGFAGVLLIFAPWHEAGLTGWGALAILGAAVSYALSFTYMGRKLVGKGHATISLSASQLIVATGLTAAALPFGGPVAMPVAPVVLVAVVALGVLCTAFTFHLTYRLIADEGATNAATVGYLLPVVSVLLGAVFLGEPLSLRIIAGMAVVLLGVGMSRWRRRTPVQPEPEVALATGRGLPGCAFNRPSSLTSASPTQAVRPPRAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAF2</accession>
    <name>D3QAF2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acetylglutamate kinase</fullName>
            <ecNumber evidence="7">2.7.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">N-acetyl-L-glutamate 5-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">NAG kinase</fullName>
            <shortName evidence="7">NAGK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">argB</name>
        <name evidence="9" type="ordered locus">Snas_3064</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14629"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the acetylglutamate kinase family. ArgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.8" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018306.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3064"/>
    <dbReference type="EnsemblBacteria" id="ADD42735">
        <property type="protein sequence ID" value="ADD42735"/>
        <property type="gene ID" value="Snas_3064"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3064"/>
    <dbReference type="eggNOG" id="COG0548">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053680_0_1_11"/>
    <dbReference type="OMA" id="EGLYEDW"/>
    <dbReference type="OrthoDB" id="901370at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003991">
        <property type="term" value="F:acetylglutamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04250">
        <property type="entry name" value="AAK_NAGK-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00082">
        <property type="entry name" value="ArgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037528">
        <property type="entry name" value="ArgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041727">
        <property type="entry name" value="NAGK-C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000728">
        <property type="entry name" value="NAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="8">
        <location>
            <begin position="32"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="72"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="297" mass="31408" checksum="CDF39EFCE896BAF4" modified="2010-04-20" version="1">MTEQLTDNVRDALGKAQTLVEALPWLERFHGKTVVVKYGGHAMVDPGLREAFAKDMVFLRYAGLKPVVVHGGGPQISSMLDKLGIASEFRGGLRVTTSEAMDVVRMVLVGQVGRELVGLINEHGPFAVGMSGEDARLFTAKRRKAMVDGEAVDIGQVGDVARVNTDAVTDLIAAGRIPVISTVAPDVDGVVHNVNADTAAAALAQALQAQKLVVLTDVDGLYGDWPDTTSLIRQISAPELKHLLPSLSAGMAPKMEACLRAVEGGVPQAHVIDGRVPHSLLLEVFTSEGVGTMVVPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB07</accession>
    <name>D3QB07_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016395.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1114"/>
    <dbReference type="EnsemblBacteria" id="ADD40824">
        <property type="protein sequence ID" value="ADD40824"/>
        <property type="gene ID" value="Snas_1114"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1114"/>
    <dbReference type="HOGENOM" id="CLU_1004391_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="277" mass="29277" checksum="35998670D65BF42C" modified="2010-04-20" version="1">MVGVSEASPEDDLKSLALGALGSKLEEFATHIGLSGVSASAPVMHEYRGLFDEVLDQVLSVTTEPEALRKGVAVIGESVANLAGMPWLAARAFGCVAGELVKPGARQVQWTPDLIGAAATEAFLIVDSAMCARNGVLAVCPSVEILIGVFGDSVVAAKLDSIMESLTISGRQFTPQSSQLASNVRKRSTTRVPWTPFAPVAGDPDFDPAAAAVAVVRRTGRREDRSGLAGIPAGFVRQLTDLLDAGEWPDDRKRDRARVISGYLRHQLDSGRKRASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB78</accession>
    <name>D3QB78_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplC</name>
        <name evidence="8" type="ordered locus">Snas_1185</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016466.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1185"/>
    <dbReference type="EnsemblBacteria" id="ADD40895">
        <property type="protein sequence ID" value="ADD40895"/>
        <property type="gene ID" value="Snas_1185"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1185"/>
    <dbReference type="eggNOG" id="COG0087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044142_4_1_11"/>
    <dbReference type="OMA" id="KRMAGRY"/>
    <dbReference type="OrthoDB" id="1270636at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="220" mass="23080" checksum="ADF7138FAFDFD3DE" modified="2010-04-20" version="1">MDRQVNGILGTKLGMTQVWDENNRVVPVTVVQAGPCVVTQVRTPDTDGYSAVQLAFGQIDPRKVNKPLSGHFAKAEVAPRRHVVELRTTDATEYSAGDEITVDRFETGGLVDVTGKTKGKGYAGVMKRHGFGGLGAGHGVQRKHRSPGSIGGCATPGRVFKGMRMAGRMGGVRHTVQNLKIHAVDADNNLLLIKGALPGPTGGLVLVRGAVKVAAKGGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBH4</accession>
    <name>D3QBH4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3186"/>
    <dbReference type="EnsemblBacteria" id="ADD42856">
        <property type="protein sequence ID" value="ADD42856"/>
        <property type="gene ID" value="Snas_3186"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3186"/>
    <dbReference type="eggNOG" id="ENOG5033857">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1199087_0_0_11"/>
    <dbReference type="OMA" id="AYAEGEW"/>
    <dbReference type="OrthoDB" id="1808650at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="218"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="251" mass="26549" checksum="432538C01101DD8D" modified="2010-04-20" version="1">MGLSTSDVEGLVETLESGKHPKVVFTDAAGQISGKVGKVVRLNRPAEGDFVVVAFGNDELPFTAEEVRVPERGELNRKPARKKTEAKPAEVPAPAGAPLLNESPAPASARRDNSRKSSARTVKETTSMNDEQPSVPKQNDGPEPAAAPAAAQAAPKKRAAKAKQAPELTVTLSWKDNEWSVSASKGTKVIAKPVPVKPSTAVSMVQSLDSPAVAAVVEDIVEQQRQEVADQAERLREELAAAEARLAELAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBM7</accession>
    <name>D3QBM7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018480.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3239"/>
    <dbReference type="EnsemblBacteria" id="ADD42909">
        <property type="protein sequence ID" value="ADD42909"/>
        <property type="gene ID" value="Snas_3239"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3239"/>
    <dbReference type="eggNOG" id="COG4637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_760562_0_0_11"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="364" mass="38910" checksum="379DD06B4BFDAB58" modified="2010-04-20" version="1">MHDHLTTDMKALADRARTVDLTERTHATARRLRTTRIAVAGVAALALAVGTGAVWTTTALPQGGNGVPPAASTDRLTTKLDGRFVFTRGSEVVTWTPGGDPEVLDGIEDPNPETFRFSPDGVLLSYLDQDGQLHVHDVADDAEIRVPDRDIVDASADPPVWTPDSQRLWIDTGREEDRYGFYDVDSGEFTPSQEPAGRDTVVVRSPDGDGEMLISLREASDGNELVSVTPDGDEQVLAESPVQGTGEYITDILSTDVDGSRMCLDTSTDQTTNPAKHPTCRTLLAYDDKAAANVAPVATPLLGWIDGDESADATSAALIAGSGQRVQQFDDRATLVTGVDEVVDEAPLPDELTDGDPELVAYQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBS9</accession>
    <name>D3QBS9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Biotin/lipoyl attachment domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020389.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5183"/>
    <dbReference type="EnsemblBacteria" id="ADD44818">
        <property type="protein sequence ID" value="ADD44818"/>
        <property type="gene ID" value="Snas_5183"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5183"/>
    <dbReference type="eggNOG" id="COG1038">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_9_1_11"/>
    <dbReference type="OMA" id="MAGNLWK"/>
    <dbReference type="OrthoDB" id="1938042at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="71" mass="7581" checksum="CEFF7FE4556D72C0" modified="2010-04-20" version="1">MAEEVRAEMVANVWKVVAKKGDTVTDADPIVILESMKMEIPVHAEDEGTVAEIAVSEGDVVSEGDLIAVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBW0</accession>
    <name>D3QBW0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_5214</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5214"/>
    <dbReference type="EnsemblBacteria" id="ADD44849">
        <property type="protein sequence ID" value="ADD44849"/>
        <property type="gene ID" value="Snas_5214"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5214"/>
    <dbReference type="eggNOG" id="COG2223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_14_0_11"/>
    <dbReference type="OMA" id="DAWWFMF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17341">
        <property type="entry name" value="MFS_NRT2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="PTHR23515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="348"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="24"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="403" mass="42142" checksum="1E6C7B8D4D3AF125" modified="2010-04-20" version="1">MSMMNSKTSAINGHTTARPGAGTNLALATVAFAVTFWAWNLVGPLSKTYTDALDLTPTQTSILVAFPVLVGSLGRIPVGVLTDRYGGRMMFTVICFVSIIPTLLVGLSHGSFTGLLLWGFFLGIAGTSFAVGIPFANAWFPPTRRGFATGVFGAGMGGTALSAFLTPQLVSAFGLLRTHLVMCAALAVMGAVMWLFARDSPDWRPSTEAALPRIRDALKIKATWQLSLLYAVAFGGFVAFSTYLPTLLTISYEFVQTDAGMRAAGFSLAAVVARPVGGMLSDRIGPVKVCLASFFGATGMAVVLSFHPPAEIPAGTSFVLMAVALGLGTGGVFALVAKLVEPARVGTVTGLVGAAGGLGGYFPPLLMGVIYQATGDYVIGFWLLAVTALLVGLFTMRVFRQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBW3</accession>
    <name>D3QBW3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020423.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5218"/>
    <dbReference type="MEROPS" id="M38.002"/>
    <dbReference type="EnsemblBacteria" id="ADD44852">
        <property type="protein sequence ID" value="ADD44852"/>
        <property type="gene ID" value="Snas_5218"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5218"/>
    <dbReference type="eggNOG" id="COG1228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023620_2_0_11"/>
    <dbReference type="OMA" id="GVTICHG"/>
    <dbReference type="OrthoDB" id="1456605at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="47"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="393" mass="41242" checksum="E24327696E0D7E37" modified="2010-04-20" version="1">MGITITNAVIFDGTDFTEGGVRIIGGEIAEVGQVSVGEKVIDAAGRTLVPGLIDAHFHAYGISVHNLEFEAGPLSYLALKGARRLGRALRRGFTTVRDVAGGDIGLSRAITEGLIDSPRYLYTGPALSQTGGHGDARPADLDICLHGGHMNEVVDGVDALRTAVRERFRTGAHAIKLMTSGGVVSPTDPLTRPQYSAEEIAAVCAEAARRGSYVAAHAYSPEAIRHSIANGVRSIEHGNLLDDATATLMAEAGAYLVPTLIAYDAMDRRGDAIGLPAVSRSKNREVLDAGRHAVELAHAAGVAVGFGSDLMGDLEDDQLLGLRLQIEASSVLDTLRSATTVNAKLLRRTDLGVIRPGARGDLLLLDGDPVADPAVLWDESRPRTVIQGGAIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBX2</accession>
    <name>D3QBX2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Succinate dehydrogenase or fumarate reductase, flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5227</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020432.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5227"/>
    <dbReference type="EnsemblBacteria" id="ADD44861">
        <property type="protein sequence ID" value="ADD44861"/>
        <property type="gene ID" value="Snas_5227"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5227"/>
    <dbReference type="eggNOG" id="COG1053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014312_7_0_11"/>
    <dbReference type="OMA" id="WRRIKVP"/>
    <dbReference type="OrthoDB" id="153138at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033765">
        <property type="term" value="F:steroid dehydrogenase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011280">
        <property type="entry name" value="Succ_DH/Fum_Rdt_flav_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632:SF53">
        <property type="entry name" value="PTHR11632:SF53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01811">
        <property type="entry name" value="sdhA_Bsu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="4">
        <location>
            <begin position="47"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="5">
        <location>
            <begin position="513"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="646" mass="71388" checksum="0640679CB1A2D5F5" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBX3</accession>
    <name>D3QBX3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_5228</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020433.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5228"/>
    <dbReference type="EnsemblBacteria" id="ADD44862">
        <property type="protein sequence ID" value="ADD44862"/>
        <property type="gene ID" value="Snas_5228"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5228"/>
    <dbReference type="eggNOG" id="COG0479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044838_3_3_11"/>
    <dbReference type="OMA" id="CPKGISL"/>
    <dbReference type="OrthoDB" id="1605514at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="149"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="247" mass="26478" checksum="738A7EEDF4B11DB2" modified="2010-04-20" version="1">MRITLRIWRQSGPKVAGAMTTYKVDDVSPDMSFLEVLDVLNEDLTLRGEEPVAFDHDCREGICGACGVVINGDPHGPSRTTTCQLHMRQFDDGDVIDVEPWRANAFPVVKDLVVDRSGFDRIIGAGGYISAPTGSAPDAHATPVPKPDADLAFDNAECIGCGACVAACPNGSAMLFTAAKVTHLNTLPQGQPERAQRVLNMVNVMDEEDFGGCTLAGECATACPKGIPFESIGNLNREFLKASLKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBZ5</accession>
    <name>D3QBZ5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase S1 and S6 chymotrypsin/Hap</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5250</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020455.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5250"/>
    <dbReference type="MEROPS" id="S01.168"/>
    <dbReference type="EnsemblBacteria" id="ADD44884">
        <property type="protein sequence ID" value="ADD44884"/>
        <property type="gene ID" value="Snas_5250"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5250"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_561004_0_0_11"/>
    <dbReference type="OrthoDB" id="1468733at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049725" evidence="4">
        <location>
            <begin position="28"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="50"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="5">
        <location>
            <begin position="408"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="287"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="292"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="467" mass="48217" checksum="18FCCCBE7CD06B65" modified="2010-04-20" version="1">MRIARAVAVVAAATLLLSAPLAGTASADPPKSKAANPTDELRPDDVGTDIVNGELASYTERPSLITGLRVGGGGPQGSSCTASVVGKRQILTAAHCMIDVGGAKSYLYGDDDLSSAGDEKWKSPVTKFTPHPDYGGSGGWRTGYDVAIVEVADDIPVPESDWAKFATSADADLSQPGRDSLTYGWGKTAANGTMGRLKKTTLPINDADSCQVFDVTVNPELMICAGYDDGRTGICSGDSGGPLIVDGVVIGITSWGASACDRYSIFARLTNAMGDWAHEQLQAPAEDDFSVSLSPDSATVEPGQSTETTVSTKVSRGSAQDVSLTATGLPDGAEATFSPSAIRSGESAKLSVSTSSDTPQGTHRITVTADGAKVDRTAVFTLQVGEDGEGPTADFTAQCFSGPGVCFFNGQGSKGEIASYRWTFGDGGTGQGQLVHHWYAAAGQYRVTLTVTDSRGGSHSTTKTITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU91</accession>
    <name>D3PU91_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1328</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41037">
        <property type="protein sequence ID" value="ADD41037"/>
        <property type="gene ID" value="Snas_1328"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1328"/>
    <dbReference type="HOGENOM" id="CLU_3066458_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="53" mass="5585" checksum="9F06610CEC5ABF7E" modified="2010-04-20" version="1">MSVTPASRAAWIVAIARASSGLPSMDNGIAPSPISPTARVPMFLSRMPITFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU95</accession>
    <name>D3PU95_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">zf-CGNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1332</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016612.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1332"/>
    <dbReference type="EnsemblBacteria" id="ADD41041">
        <property type="protein sequence ID" value="ADD41041"/>
        <property type="gene ID" value="Snas_1332"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1332"/>
    <dbReference type="eggNOG" id="ENOG503487J">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1840920_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010852">
        <property type="entry name" value="ABATE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023286">
        <property type="entry name" value="ABATE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021005">
        <property type="entry name" value="Znf_CGNR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35525">
        <property type="entry name" value="PTHR35525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11706">
        <property type="entry name" value="zf-CGNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160904">
        <property type="entry name" value="SSF160904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-CGNR" evidence="2">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="152" mass="15768" checksum="2CBC13A6C69092FB" modified="2010-04-20" version="1">MTVPDFGELDPELARAEAALADGGALAGVRSALPDEAAAARFLNAVLADSGATPRLRRHAAGWRIVTLSAAAGAGDLAATASGLANLVAADGWRRVKQCSRPGCVATFIDRTNGVTRRYCRDHSRHEIPLGKGMSPPRPTTSAADDRPASQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUE1</accession>
    <name>D3PUE1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3285"/>
    <dbReference type="EnsemblBacteria" id="ADD42954">
        <property type="protein sequence ID" value="ADD42954"/>
        <property type="gene ID" value="Snas_3285"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3285"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_8_3_11"/>
    <dbReference type="OMA" id="MPHIDRS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="128" mass="14279" checksum="7EC6DB4F86DE1031" modified="2010-04-20" version="1">MAMTTPTITRYTIGEASRRSGFSMDTLRYYEKIGLLVDVDRSSTGHRCFTDEDLGWLGTLKCLRDTGMPVADMLAFAELTRAGDHTIPQRVALLESHHARVSEHIADLRTKHDGIAAKIAWYRGVLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUJ8</accession>
    <name>D3PUJ8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TAP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3345</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3345"/>
    <dbReference type="EnsemblBacteria" id="ADD43011">
        <property type="protein sequence ID" value="ADD43011"/>
        <property type="gene ID" value="Snas_3345"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3345"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_3_2_11"/>
    <dbReference type="OMA" id="QPSKCIN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048003" evidence="2">
        <location>
            <begin position="29"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="85"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="532" mass="56894" checksum="DCBCD0E99C36EC51" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV32</accession>
    <name>D3PV32_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1378"/>
    <dbReference type="EnsemblBacteria" id="ADD41085">
        <property type="protein sequence ID" value="ADD41085"/>
        <property type="gene ID" value="Snas_1378"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1378"/>
    <dbReference type="HOGENOM" id="CLU_131550_3_3_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="1">
        <location>
            <begin position="4"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="58" mass="6375" checksum="F5FC91233D9E986B" modified="2010-04-20" version="1">MEGQWKKSSHSGGDSSNCVEARVYGPRFQVRDSVLGDDSPILNLTNTDFNGFLASVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV83</accession>
    <name>D3PV83_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016707.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1430"/>
    <dbReference type="EnsemblBacteria" id="ADD41136">
        <property type="protein sequence ID" value="ADD41136"/>
        <property type="gene ID" value="Snas_1430"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1430"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102175_0_0_11"/>
    <dbReference type="OMA" id="TATIKYY"/>
    <dbReference type="OrthoDB" id="1748559at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="210" mass="22534" checksum="6C90B8840799B30D" modified="2010-04-20" version="1">MRVAELSRTSGVPVPSIKYYLRAGLLPPGERTAPNQADYGDSHVHRLRLIRALIEVGGLSVAAVKEVLESVDAQGADLHEALGSAFAATLPARTAEEESEYTETARRTAADLIERHGWLVGSDSKNVEALVSALAVMYRLQQHDVESMVELYAQHANTMATREVAWVAERGDIDAVVEAAVVGTFIGGAVFNAMRVIVHESASKKTLAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVM6</accession>
    <name>D3PVM6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3476</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018711.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3476"/>
    <dbReference type="EnsemblBacteria" id="ADD43140">
        <property type="protein sequence ID" value="ADD43140"/>
        <property type="gene ID" value="Snas_3476"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3476"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_2_3_11"/>
    <dbReference type="OMA" id="CPAHEST"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="4"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="147"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="296" mass="31777" checksum="41B6E0C77D74A378" modified="2010-04-20" version="1">MSAPITVAYDGSQQSSDAVEWAVTEARHWRRPLRIITVSLALPPLRRDSQSDVTTAHNAVKDIAREMAEETLRKAPDLDVQYEVIEAPTAAGGLIPRSSTWEMLVLGTHGRGGFTGMLVGSSTTQVCAYSMCPVVVARKPYPESAPVTVGVDGSRGSRSAVGFALREAWLRDVPLNLVHAWRHPKSARDVDFAAGAELSDYLAADRQTVMTRSLAGLVSRFRDVPITRRSVQGGTRTVLLRESAHSSLLVVGARGRGGFTGLLLGSTSQAMIHHAKIPVAVVHGTETPSDGTRPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW90</accession>
    <name>D3PW90_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016818.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1544"/>
    <dbReference type="EnsemblBacteria" id="ADD41247">
        <property type="protein sequence ID" value="ADD41247"/>
        <property type="gene ID" value="Snas_1544"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1544"/>
    <dbReference type="eggNOG" id="COG1234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031317_3_0_11"/>
    <dbReference type="OMA" id="HIPPWTD"/>
    <dbReference type="OrthoDB" id="1712770at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="18"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="252" mass="27106" checksum="F27787114E32A4A1" modified="2010-04-20" version="1">MKLTVIGCAGSFPGPDSPCSSYLVEADGYTLLLDFGSGSLGALQRHTDPYKLDAILLTHLHADHIMDACPYVVMRRYAPGAPFPQVPLYGPEGTERRLAAAYGGAGEAACPSLSDVYDVHTLQPSTFNMGPLKVTVDKVCHPIETYGVRIEHDGRTLVYSSDTGQCEVLERLAKKGDVFLCEASYLEGRPNPPGVHLTGREAGECATKADVGRLLLTHLVRRWGSEEQTLAEARSAYSGPVEVVHSGATFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWE5</accession>
    <name>D3PWE5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell division FtsK/SpoIIIE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1599</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1599"/>
    <dbReference type="EnsemblBacteria" id="ADD41302">
        <property type="protein sequence ID" value="ADD41302"/>
        <property type="gene ID" value="Snas_1599"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1599"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008270_1_0_11"/>
    <dbReference type="OMA" id="YPPHALI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsK" evidence="3">
        <location>
            <begin position="365"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="383"/>
            <end position="390"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="886" mass="95959" checksum="89067F4DBCAD666C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWR3</accession>
    <name>D3PWR3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mrr_cat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018856.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="REBASE" id="24810">
        <property type="entry name" value="SnaDMrrP"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43285">
        <property type="protein sequence ID" value="ADD43285"/>
        <property type="gene ID" value="Snas_3625"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3625"/>
    <dbReference type="eggNOG" id="COG4127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047680_0_0_11"/>
    <dbReference type="OMA" id="DWVITYS"/>
    <dbReference type="OrthoDB" id="1136895at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016984">
        <property type="entry name" value="UCP031853"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031853">
        <property type="entry name" value="UPC031853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mrr_cat" evidence="1">
        <location>
            <begin position="208"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="346" mass="37533" checksum="8E2603C434A10890" modified="2010-04-20" version="1">MGVAWVVRSGRNGERDQWALANGVSGGGWREWPDLTACKSREDIAAVITKILPDMGMATQANYTGQTWALRGRIAKGDLIVMPMKTTKQLAMGRVTSGYEYLADQPDPDQRHVVRVDWQRTDLPRSAVKQDLLYTLGSALSIFAPTKGHAIARLEALLETGEDPGLVSFSTPVSLSESAGADDVDEPETHTDIEEVARDRITARIAEEFAGHDLALLITAILRAEGYVCTMSPPGADKGIDIVAGGGLLGMDSPRLIVQVKSGGQISDTVVRDLGGVIHSQRADQGLLVAWGGLTKSARASVYGQQFRIRAWTAEDVVDAVTRVYDRLPEDIRSRLPLTRVWMLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWX9</accession>
    <name>D3PWX9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5572</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020774.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5572"/>
    <dbReference type="EnsemblBacteria" id="ADD45203">
        <property type="protein sequence ID" value="ADD45203"/>
        <property type="gene ID" value="Snas_5572"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5572"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_87_2_11"/>
    <dbReference type="OMA" id="DSGMHQH"/>
    <dbReference type="OrthoDB" id="1757088at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="152"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="251" mass="27381" checksum="7806973FEBA56A8F" modified="2010-04-20" version="1">MSEVIEEAAPTGVGAIVVGTFPLASGEWIRPHRHPQHQLAWSRGGVLGVAVDDTHWILPPTRALWIPAGIVHRTGASREAVLRSLYFEPDRCPLTWTEPTPVAVDGLLAHLIGHLGRDDLATDARLRAEAVVFDLLHPLPATPIDVPDATDERVRAVTEHLLADPADRRGLDVHARAVGVSRRTLTRLFVHDTGMSFDRWRTHMRLRAALPLLAAGRTVADAARSVGYATPSAFVAAFRRTVGTSPKRYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX02</accession>
    <name>D3PX02_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020797.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5596"/>
    <dbReference type="EnsemblBacteria" id="ADD45226">
        <property type="protein sequence ID" value="ADD45226"/>
        <property type="gene ID" value="Snas_5596"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5596"/>
    <dbReference type="eggNOG" id="ENOG5032Z57">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151995_0_0_11"/>
    <dbReference type="OMA" id="KFVNYHV"/>
    <dbReference type="OrthoDB" id="2002921at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025438">
        <property type="entry name" value="DUF4180"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13788">
        <property type="entry name" value="DUF4180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4180" evidence="1">
        <location>
            <begin position="9"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="123" mass="13452" checksum="E7D312CFB609B23E" modified="2010-04-20" version="1">MTAMVTRQNGTTVLKLPADGPQLREVEDFVDLLGEAMANEADLVVIPADRIADKFFQLRSGLAGEVTQKFVNYRTRLVIIGDISTHTADSSALAAFVAESNRGDQLWFLPDRATLDDRLADGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX55</accession>
    <name>D3PX55_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4097 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5649</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020850.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5649"/>
    <dbReference type="EnsemblBacteria" id="ADD45279">
        <property type="protein sequence ID" value="ADD45279"/>
        <property type="gene ID" value="Snas_5649"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5649"/>
    <dbReference type="eggNOG" id="COG3595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076844_2_0_11"/>
    <dbReference type="OMA" id="RIEMNGV"/>
    <dbReference type="OrthoDB" id="1508494at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4097" evidence="3">
        <location>
            <begin position="131"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="266" mass="28044" checksum="9F2F0E962AC3D654" modified="2010-04-20" version="1">MSEHSVEKPACGGLVRWLVALAVVVVLAAVGIFFWKNVIGGVPQEDVQSKVHSKPISRLVVAGDSGEVDVVKGDKVHIEATLEWQGERKPVNSQKWDGETLRVEEKGCRGAWDFVGECGITYRIEVPSDVDLEVRVDAGNITTSGIKGEQRLESDSGNIDVSDAGKALTVKADSGNVTGTDLAGTKVNVTLDSGQIDLGFSKAPSQVRAVADSGSVTVQLPEGDEGYDVHAETDSGTSDVEVSTDSTSSRRINVETGSGSVTVEYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXB4</accession>
    <name>D3PXB4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1677</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1677"/>
    <dbReference type="EnsemblBacteria" id="ADD41377">
        <property type="protein sequence ID" value="ADD41377"/>
        <property type="gene ID" value="Snas_1677"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1677"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_2_1_11"/>
    <dbReference type="OMA" id="LYWHFKD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003012">
        <property type="entry name" value="Tet_transcr_reg_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00400">
        <property type="entry name" value="TETREPRESSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="6">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="24386" checksum="D6CC1F3260440FB3" modified="2010-04-20" version="1">MCLNSVKLSTVSLSREKLVSVGLELLDEHGLEGLSLRKLATELDVQASAIYWHFKNKQELLDEMATAMFRRLLTDTEWPQPRDWRDGLERLGVELRAMLLSRRDGAKMAAGTYLTDDSLLSSMEIPLRFLTEAGFPLRDAVRAFITVYSFTVGFTIEEQAVAGDPRYADTARRSRIDAEKYPLSASAGPEIFGTPDERFEHGLRVIIAGVGAYASEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXJ3</accession>
    <name>D3PXJ3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018894.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3665"/>
    <dbReference type="EnsemblBacteria" id="ADD43323">
        <property type="protein sequence ID" value="ADD43323"/>
        <property type="gene ID" value="Snas_3665"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3665"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093174_0_0_11"/>
    <dbReference type="OMA" id="AWWRYAD"/>
    <dbReference type="OrthoDB" id="1902621at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="261" mass="27095" checksum="C730630953270D05" modified="2010-04-20" version="1">MNTMSAAIGFEWLKLRRARLTWVATVVLGLAVPLLSTGLLAAARSDSTSQLAVKARTMATETGWSGQFTVAGQFLSVAVLVVVGVVACWIFGREFTDRTVAGLLSLPTTRIQFAVAKFTVLSAWATVTCALAAVTIVVAGLVTETGALRAHDWAVLGKLFLAALLTIILTAPLALASSLWRGYLAGIGILFGLLVVTQLATAAGLGGWFPYAAPGLWLGLGGTDAAAAITLPQLLLPLPIGLGAAVATLLWWNGNGPTENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXQ9</accession>
    <name>D3PXQ9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock protein DnaJ domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3732</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018960.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3732"/>
    <dbReference type="EnsemblBacteria" id="ADD43389">
        <property type="protein sequence ID" value="ADD43389"/>
        <property type="gene ID" value="Snas_3732"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3732"/>
    <dbReference type="eggNOG" id="COG0484">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_762155_0_0_11"/>
    <dbReference type="OMA" id="SWLPGHY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="5"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="423" mass="45875" checksum="9E4345E97004518B" modified="2010-04-20" version="1">MTEPDYYRILGLTTSAEIAEIRQAYRRKVRDAHPDAGGDPEVFHELQEAYETLTDPVLRLEYDAARGTRKPPWGNRRRPGRHTKSHKVKAWRVNTTVDKPANKNAAPTTPPGAGEVMSLPWFVDIDPTKRLRYTPSVWQRGGIAAGIGAAWTYLTIQVSALVLASDTITVLKALIVPYMLLVAGVVAVACFRGLRPTRPTSFIVTGVVALVVVWLSGATLGGILLALHLVASAVLPWSVRRVRIAARLRAAVRSALKDFNAFAPSGAKPSADRRTGAVLRTLLERLPAARLFVRVPVGVHRAEYTVVCGRRVAVIAPPVPRSTGDSGAEALPSAVHDVSQLLNEATVRGFVVWPNLPVDRISGADAVIRHLSAPDAAGEIGRWLANDPYTLHLPTLRRLRDRLAAADGAESARKAPPRSTIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXS3</accession>
    <name>D3PXS3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Oxygen sensor histidine kinase NreB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nitrogen regulation protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Snas_3746</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018974.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3746"/>
    <dbReference type="EnsemblBacteria" id="ADD43403">
        <property type="protein sequence ID" value="ADD43403"/>
        <property type="gene ID" value="Snas_3746"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3746"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_13_11"/>
    <dbReference type="OMA" id="HGGFAQF"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="12">
        <location>
            <begin position="181"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD43403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="373" mass="39921" checksum="EB6C6C8B33ADE174" modified="2010-04-20" version="1">MTDREDTDEVLSAVSTAVLSVTRHLSVAEVLEVIVRSSRQLLRARYAALGIPDEGGGFAEFITDGISERQRAAIGPLPRQHGMLAALLHEGETIRSRDIRADARFGYFPTAHPNMTDFLGVPIRDGDETVGIIFLADKECGFTERDEALLTLFASHAAIALANARLYEQAHELSVVQERTRLARELHDAVSQKLFSLRLAASSARALAASDADAALSQLEKVESLAAEAARELREVIVELRPADLDVHGLAGTVRKHLRLVERLHAVRTEFTVHGDPGVPAGAELEVLRVIQEAVHNAVRHSHADLVRVTLCGGPEFLAEISDDGSGFDPGADNGGGLGIESMRERVAGVGGRLDIDASIGGGTTVRLAVPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXV0</accession>
    <name>D3PXV0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3773</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3773"/>
    <dbReference type="EnsemblBacteria" id="ADD43430">
        <property type="protein sequence ID" value="ADD43430"/>
        <property type="gene ID" value="Snas_3773"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3773"/>
    <dbReference type="eggNOG" id="COG0559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039929_3_0_11"/>
    <dbReference type="OMA" id="NMGWFLI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="320" mass="33533" checksum="38AEA63705F969E5" modified="2010-04-20" version="1">MDFPYLVSHFLGTTMDGLVIGGIYALIALGYTLVYGVLKLINFAHSEVFMLGAFAAVGIWTVLGVNEGPTPSLGGFILLAIVGLAAAMAASGGTALALEYIAYRPLRRKKAPRLVFLITAIGVSLALNEGMGVLTSRDDVGVPEVFKQTILIDWDSGALGRLRVSDLDIGIIVMAFGLLVALDMFVNRTRPGAGIRAVAQDPDTAALMGINKNRIFALTFILGGLAAGVAAVMWDLRYSSIKHSLGFLLGVKAFTAAVMGGIGNLRGALVGGFALGLIENWSGAVFGNAWLDVVAFTVLVVVLMFRPTGLLGESLGRSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY23</accession>
    <name>D3PY23_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5722</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020923.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45352">
        <property type="protein sequence ID" value="ADD45352"/>
        <property type="gene ID" value="Snas_5722"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5722"/>
    <dbReference type="HOGENOM" id="CLU_1561934_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="171" mass="18818" checksum="3886D8A175632511" modified="2010-04-20" version="1">MNQLDADAIITSLRTGTWTTADLVRIAHALAQHGKNTTSILGQFGEELVAKAFNGTVAPFHQKAFDVRTPKHGDLQVKTFSVGKRAGVIRSFTHDVVTVEIDPATASVRSAKLYAADDLYAEFKRLFDGKYAALGMTWGGRQQDRFERGWTIPSGVVPSTDVTDRFRSTEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYN0</accession>
    <name>D3PYN0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Glutamate synthase (Ferredoxin)</fullName>
            <ecNumber evidence="17">1.4.7.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Snas_3807</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.7.1" evidence="17"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019034.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3807"/>
    <dbReference type="MEROPS" id="C44.003"/>
    <dbReference type="EnsemblBacteria" id="ADD43463">
        <property type="protein sequence ID" value="ADD43463"/>
        <property type="gene ID" value="Snas_3807"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3807"/>
    <dbReference type="eggNOG" id="COG0067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0069">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_8_2_11"/>
    <dbReference type="OMA" id="RVMGPEQ"/>
    <dbReference type="OrthoDB" id="5568at2"/>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016041">
        <property type="term" value="F:glutamate synthase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="16">
        <location>
            <begin position="32"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ADD43463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1502" mass="161715" checksum="14A5EB7775DE8169" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYU8</accession>
    <name>D3PYU8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endolytic murein transglycosylase</fullName>
            <ecNumber evidence="7">4.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Peptidoglycan polymerization terminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mltG</name>
        <name evidence="9" type="ordered locus">Snas_3876</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transglycosylase MltG family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019102.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3876"/>
    <dbReference type="EnsemblBacteria" id="ADD43531">
        <property type="protein sequence ID" value="ADD43531"/>
        <property type="gene ID" value="Snas_3876"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3876"/>
    <dbReference type="eggNOG" id="COG1559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025574_4_1_11"/>
    <dbReference type="OMA" id="TDWDPGP"/>
    <dbReference type="OrthoDB" id="708179at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02065">
        <property type="entry name" value="MltG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003770">
        <property type="entry name" value="MLTG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30518">
        <property type="entry name" value="PTHR30518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02618">
        <property type="entry name" value="YceG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00247">
        <property type="entry name" value="TIGR00247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="331"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD43531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="395" mass="43125" checksum="1E7C3BBA8FB6F5AB" modified="2010-04-20" version="1">MLDERPYETMDPSQPRRRRHRRRRKGRTVFALLLVFVLLGTVGVVGFVGFDKIKNIFSAPDYAGDGNGVKVQVEIAEGSVLSDIGDALYKKDVVKSANAFVNAAEANPKSNQIGPGTYAMEKQMSGEAALERMLDPKSRKVSGVTIREGLTMWGTFKKLSENTGVPLEDFTAAAEDPEALGITSDWFERKDGKDVVKSVEGFLSPATYEFKKGATAEEMLKAMVSNFLKVTDSIGFKETVEAQRSNYSPYEVLIVASLSEAEAGVPKDLGKIARVAYNRMDGEYWCHGGLENCLEFDTTTNYGLIEAGKGSKNSKDLTDAELNDESNKWSTHVRAGLPPTPINSPGKSALEGAADPPSGKWKFFVAIDKEGNSAFAETKEEHDANVEEARKNGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYW6</accession>
    <name>D3PYW6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidoglycan-binding domain 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019120.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3894"/>
    <dbReference type="EnsemblBacteria" id="ADD43549">
        <property type="protein sequence ID" value="ADD43549"/>
        <property type="gene ID" value="Snas_3894"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3894"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1133052_0_0_11"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="178"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="245" mass="26587" checksum="928DB23FAEBD9F4E" modified="2010-04-20" version="1">MANPDPDKITDEMWQLWTECEQVISGVRLGGIWADKPGYHNTVDANQANWPDNYSIQLGLDLESPHTKARAIDLTMSDAQMRLHTGRLRAAALDGDPRLSAVREFYGTLDSQNVYGLIKDSTTGSWRSSSSDSSHLWHIHISVFTTFVNDWDSLAPIVSVLADSEGDDDVIGLKKGNSGERVKGLQAALGRAGYPVDVDGEYGPKTAAALLEMRKDMGSSAENGDKVTGYAYAQLLSALAKKQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ32</accession>
    <name>D3PZ32_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021032.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5831"/>
    <dbReference type="EnsemblBacteria" id="ADD45461">
        <property type="protein sequence ID" value="ADD45461"/>
        <property type="gene ID" value="Snas_5831"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5831"/>
    <dbReference type="eggNOG" id="ENOG5032VEE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125896_0_0_11"/>
    <dbReference type="OMA" id="WCAADSE"/>
    <dbReference type="OrthoDB" id="1469388at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028961">
        <property type="entry name" value="Imm21"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15589">
        <property type="entry name" value="Imm21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="186" mass="20236" checksum="5DA53C1AE1DFEB6A" modified="2010-04-20" version="1">MESGPSRRHLTWVETDGGPIVVLQAATAARWSGVDGTDDSDDVTTWGDYGRACTVDEYHGLVEFDSAQPPLTALVLGDEPQSSTYLPKHRVIARWTCADSEDQLLDMIDTRIPDAHWQSPLHWHVSAGGLVMFDSAYALADFGPGGCATESPLHIDLPAGPYEVTLAFVATTDERAMATLHRFAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ44</accession>
    <name>D3PZ44_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipolytic protein G-D-S-L family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5844</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021044.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5844"/>
    <dbReference type="EnsemblBacteria" id="ADD45473">
        <property type="protein sequence ID" value="ADD45473"/>
        <property type="gene ID" value="Snas_5844"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5844"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069365_1_0_11"/>
    <dbReference type="OMA" id="GHANMAK"/>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="10"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="258" mass="28774" checksum="D8853B5F22E837B5" modified="2010-04-20" version="1">MAERFTGYVALGDSFTEGMNDHGGDGIFRGWADLAATRMAEADPELKYANLAIRGKLFDEVVDEQVPAALRLRPDLVSFVAGGNDALRTSFDPARMAGRFHEAIRVLTASGARVLMSTGFHPPRLPAHRLLRKRIVALNEIIRKVAKRHDAALVDLFADEAFADTRMWSEDRLHMSALGHRRVAHHVCQALSVDPDPKWSAPLPTAPGKSWLRRRREDAAWTREHALPWVQRRFTGQSSGDMITPKRPQLMPVSQVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZD7</accession>
    <name>D3PZD7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1915</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017182.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1915"/>
    <dbReference type="EnsemblBacteria" id="ADD41611">
        <property type="protein sequence ID" value="ADD41611"/>
        <property type="gene ID" value="Snas_1915"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1915"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_5_1_11"/>
    <dbReference type="OMA" id="IKYICMS"/>
    <dbReference type="OrthoDB" id="384611at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="21"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="485" mass="51153" checksum="71A065B735F2D880" modified="2010-04-20" version="1">MPSETSVVASVAKELFIGGKWTGATGGKTFEVRDPATGEVLCQVADASPADGVAALDAAVAAQKSWANHPPRERGEILRRAYEQLMARVDELALLMTLEMGKPLAEARGEIAYAAEFFRWFAEEAVRIDGGYATAPNGTGRFLVAKQPVGPALLITPWNFPMAMGTRKIGPAVAAGCTMVIKPAAQTPLSMLALAQILADAGLPEGVLNVLTTTNSGGVMEPLIRDGRARKLSFTGSTAVGRKLLEQCAEKVVNTSMELGGNAPFLVFEDADLDAAVDGAMQAKMRNIGEACTAANRFYVQRGVAEEFARRMTERMAAQPIGRGTEDGVIVGPLIDEAAVTKVSGLVDDAKQRGARVLTGGSVVEGPGNFYQPTVLADVPTDARMANEEIFGPVAPISVFDTEDEALELANDTEYGLVSYLYTSDVKRALRVAERLEAGMIGLNQGIVSNPAAPFGGVKQSGLGREGGTVGIEEFLETKYIAVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZG8</accession>
    <name>D3PZG8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1946</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017213.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1946"/>
    <dbReference type="EnsemblBacteria" id="ADD41642">
        <property type="protein sequence ID" value="ADD41642"/>
        <property type="gene ID" value="Snas_1946"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1946"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_7_3_11"/>
    <dbReference type="OMA" id="KMISEYM"/>
    <dbReference type="OrthoDB" id="1308416at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="162" mass="17774" checksum="80DE38FBBE617FBD" modified="2010-04-20" version="1">MPTPDFILELREKIGHDLLWLPSVTAVVLDDAGRVLLVRRADNHNWTLVTGCLEPGEQPAVGAVREVLEETGVEAVAERLIGVQATPEAVCANGDKVQWLDVAFVCRAVGGDARVNDDESIDVGWFAPDLLPQPLGPRQTRQLAEALGDEQRAYFLDEVRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZU2</accession>
    <name>D3PZU2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3977</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019200.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3977"/>
    <dbReference type="EnsemblBacteria" id="ADD43629">
        <property type="protein sequence ID" value="ADD43629"/>
        <property type="gene ID" value="Snas_3977"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3977"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="ATHRYVE"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="711"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="831"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="962" mass="104515" checksum="F4AE3B86FDB1C688" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZV1</accession>
    <name>D3PZV1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polar amino acid ABC transporter, inner membrane subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3986</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019209.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3986"/>
    <dbReference type="EnsemblBacteria" id="ADD43638">
        <property type="protein sequence ID" value="ADD43638"/>
        <property type="gene ID" value="Snas_3986"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3986"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_3_11"/>
    <dbReference type="OMA" id="EPFMVYG"/>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="71"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="33452" checksum="8BB374EDE8210A59" modified="2010-04-20" version="1">MSKQETSVLFDALGPKGKQRARIVSVVAGLLIAAFVTYAVIILSSNEFFSAEAWNTVFDAQLFETIWVKGLLGTLRAAFFGCIGALVIGVIVGMGRVSRFKFIRAISAVYVQFFRSIPLLLLIWIPYAINLYYGYMDALFTDEIWQLTSFVVIGLSIYNGAVLAEILRSGINALPPGQAMAGHAVGLRHGQVMRSIVMPQAIRNMLPAVLAQLIILFKDTSLGYAITYPELLHEARLLGSNFNVALLQSLFTVAFVYFIIAYTAGKLVNVVDRKMSRKTAGKTVGGTDDTAGLAALPIAAASDADGGGNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZZ4</accession>
    <name>D3PZZ4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021094.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5895"/>
    <dbReference type="EnsemblBacteria" id="ADD45523">
        <property type="protein sequence ID" value="ADD45523"/>
        <property type="gene ID" value="Snas_5895"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5895"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_986561_0_0_11"/>
    <dbReference type="OMA" id="HAVAIND"/>
    <dbReference type="OrthoDB" id="1088187at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048507" evidence="1">
        <location>
            <begin position="39"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="290" mass="30745" checksum="D88A582F042BA7ED" modified="2010-04-20" version="1">MNESTGMRAKRSRRWVLGTGVAAAIAVPTVWVANSALAEDTRLASVDMELVLVAAQVDPRKSGTGTTPGAKDHVQRVEQALQAKGLLKAAQVDGHYGTSTVSAYSAWQKKLGYTGLDANGMPGKTSMTKLGEGRFTVSRAVSVGSNSDSYGGKRVNSRTKSMLAAADSKLSWSIKLTQGSYTSANPGSAGTHDGGGVVDISVSGLSSTQRWQMVKALRTVGFAAWLRTPDQGFAYHIHAVAVADPDLASAAQPQVHDYYYGKNGLASHGADNTPSSYRVGFTWWEKYKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q025</accession>
    <name>D3Q025_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5926</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021125.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5926"/>
    <dbReference type="EnsemblBacteria" id="ADD45554">
        <property type="protein sequence ID" value="ADD45554"/>
        <property type="gene ID" value="Snas_5926"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5926"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_34_1_11"/>
    <dbReference type="OMA" id="HEGNTSE"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="22"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="480" mass="48558" checksum="7A122777E1101E1F" modified="2010-04-20" version="1">MQGNGTVDIDARRSTRWTGRLVGLVVTLALVNFMVDSAITAPLVVLPDMLDYFDTDQAAWLNASAMLAGVMWAPLLGKSADVHGKRRVLVLTLLISGAGAVLCAVAPNIWVFVPGRLLQGAALAAMFLAVAIVREVFPARAAMIVVGVVTSGTAVLNIASRFLVERLAADFGFHILFLISAGVAAAMAICVFVVVPESRITTPGRIDFGGAVLLGGGLAGTLSYISLGSTFGWLAPGPLALLVVGAAALTRWFLTSSRKPEPLIDVRNLGRPLVLTLLVIFLAAGSYQSMLQLVSLIGGVSTGQDLGYGLADQGSVALLLALPAIGVTLGGPVSGVLATRVGPAATLAGAVLLGTVGTLGMFLGASQLAAALASAFLLGLTVGALGTAGFNMAGSLAPADKQGVVSSLVMVVVSVGAVVLDFVGTAVLTSTATVVDDETANTALGVFSYIAIATVAFALAAVLAVKLARGSRPVAAESRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0F8</accession>
    <name>D3Q0F8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015393.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0101"/>
    <dbReference type="EnsemblBacteria" id="ADD39822">
        <property type="protein sequence ID" value="ADD39822"/>
        <property type="gene ID" value="Snas_0101"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0101"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_14_0_11"/>
    <dbReference type="OMA" id="HACEYWR"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="333" mass="34365" checksum="A91B67384F95A55B" modified="2010-04-20" version="1">MGHLDGRIALITGAGRGIGEAVARYFAAEGARVVVNDLGVDIDGTGADASVAETVAASIRADGGAAIANTDDVADWDGARRAVASAVDGFGDLHVVVNNAATERNLGLVDMTEADFDSVVGVSLKGTFAVSHWAARFWRERFEAGERVDRSLVNTASGSGLLNPLPTQTNYAAAKAGVAAMTLIHALELGRYGVRVNCSSPSMVRTRLTENVAGMPQPRAEGFDPTAPVTSAPLVAYLATAECGLTGQVLSMRGSTVLVNRNWSKGPHLSKGEELWTVDELAAALPDLSPDDPFQTLAAALDGALGSRLGEEGRAGVRRMVDAALDAAAAGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0P5</accession>
    <name>D3Q0P5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017352.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2087"/>
    <dbReference type="EnsemblBacteria" id="ADD41781">
        <property type="protein sequence ID" value="ADD41781"/>
        <property type="gene ID" value="Snas_2087"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2087"/>
    <dbReference type="eggNOG" id="ENOG50346D2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2094275_0_0_11"/>
    <dbReference type="OrthoDB" id="2191287at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="15"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="122" mass="13334" checksum="764883265D5D0DF2" modified="2010-04-20" version="1">MSFDSKALDAHIALFNKAVTSGDFSAFTASFAPDAVMKFAGVPAGPYLGRDAIASAYAENPPDDTMTVLSHDWDGDRLIARFKWDSGGMGQLSLRWRENLVTQLFIAFDPHPLPQEKEPTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0V7</accession>
    <name>D3Q0V7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4055</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019278.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4055"/>
    <dbReference type="EnsemblBacteria" id="ADD43707">
        <property type="protein sequence ID" value="ADD43707"/>
        <property type="gene ID" value="Snas_4055"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4055"/>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_16_6_11"/>
    <dbReference type="OMA" id="WSQRCAG"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="892"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="974" mass="103695" checksum="A4AEAC12A47A5A02" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0W3</accession>
    <name>D3Q0W3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_4061</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019284.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4061"/>
    <dbReference type="EnsemblBacteria" id="ADD43713">
        <property type="protein sequence ID" value="ADD43713"/>
        <property type="gene ID" value="Snas_4061"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4061"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_9_11"/>
    <dbReference type="OMA" id="ITITHQL"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="29"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="339"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="372"/>
            <end position="379"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="579" mass="62215" checksum="9DCCEB457C7F7C7F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Y0</accession>
    <name>D3Q0Y0_STANL</name>
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        <submittedName>
            <fullName evidence="1">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4078</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4078"/>
    <dbReference type="EnsemblBacteria" id="ADD43730">
        <property type="protein sequence ID" value="ADD43730"/>
        <property type="gene ID" value="Snas_4078"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4078"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_9_2_11"/>
    <dbReference type="OMA" id="WSLAMNA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="474" mass="53118" checksum="D13DA69A4E60E85C" modified="2010-04-20" version="1">MNDNQLTGQGRNRRDVLRLAGLGAALTVSAPMLQACGFGGGTQSGDSAANDITGSFDWKKYDGKTVKLLMNKHPYTDALKKHKGEFEKKTGITLEIDEFPESNYFDKVTLELQSKQGNYDAFMLGAYMVWQYGPPGYLEDLGPWMKNESATHEEFEKEDFFPNLLKAGQWNFTNGDPLGGKQQWMLPWGFETNVVCYREDVFKKLKLKPAEDFDEFIDLAKTLDKKAGDGMYGVAVRGSKEWATIHPGFMTMYSRLGLKDFDVKDGKLVPTMNSADAVDFTDKWAKMVRDSGPKGWTSYTWYQASSDLGAGKAAMLFDADSASYFQNEGTKAAGKLAWHPGPKGPNGSLDTNMWIWSLAMNANSKNKEAAWWFLQWATSKEHLKYAATKGQHIDTVRQSIAESSEYKDKFADYTGFLDTFEKVIDDTKIQFTPQKNFFDATTSWAEALQTIYGGEDAKSTLDDLASNLESRVND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Z3</accession>
    <name>D3Q0Z3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SMI1_KNR4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4092"/>
    <dbReference type="EnsemblBacteria" id="ADD43743">
        <property type="protein sequence ID" value="ADD43743"/>
        <property type="gene ID" value="Snas_4092"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4092"/>
    <dbReference type="eggNOG" id="COG4282">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085722_0_0_11"/>
    <dbReference type="OMA" id="WHAQWIP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00860">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SSF160631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMI1_KNR4" evidence="1">
        <location>
            <begin position="26"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="192" mass="21344" checksum="064509EC36E4A3EB" modified="2010-04-20" version="1">MTQSWARIESWLAVHAPRTLADLDPPATAEEIAAAERAIGLTFPAALVESLLRHAGTGRVNMLPLWGLSDPAEIVREWRLLNGLWNDDADAKARLAQLDHDAEVDDLMWHPQWIPLGRDYGGGGLVIDLRANGRTGRIGERDRDEGTLFDDEELWRTSLPALLSELARCLETGEQFTGYAPKAEQGELLWDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q116</accession>
    <name>D3Q116_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inositol monophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4115"/>
    <dbReference type="EnsemblBacteria" id="ADD43766">
        <property type="protein sequence ID" value="ADD43766"/>
        <property type="gene ID" value="Snas_4115"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4115"/>
    <dbReference type="eggNOG" id="COG0483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044118_4_0_11"/>
    <dbReference type="OMA" id="SRCTMAS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="288" mass="31106" checksum="6AB02E7CE11FCFC1" modified="2010-04-20" version="1">MGAMPDRRWSSTSDVRIIERVPDIPPVDQKLLAFAVRTVWEAGEVSAARFFSGSRTVTKSDGSVVTDTDLEVEKLILGRLAERYPEDGSLGEETGEHTGRSGRRWIVDPISGTAFFVLRMPLFANLLAYEDEHGPAVGIVNLPMQRELVYAGRGLGCWRITEADGQPVACRVGDRPNAKGALTLAMNQQTWSTELVAALHGHVDLVGAINHPVVHLVTGRVDAMVMTGQGYDDRAGLPLIVEEAGGVVTDLDGAPLLSGDGSVLATNGRWHEELVDLVKGLPRLKSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q131</accession>
    <name>D3Q131_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_4130</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4130"/>
    <dbReference type="EnsemblBacteria" id="ADD43781">
        <property type="protein sequence ID" value="ADD43781"/>
        <property type="gene ID" value="Snas_4130"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4130"/>
    <dbReference type="eggNOG" id="COG3290">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002554_3_1_11"/>
    <dbReference type="OMA" id="RRNVNAM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013587">
        <property type="entry name" value="Nitrate/nitrite_sensing"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08376">
        <property type="entry name" value="NIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048536" description="Histidine kinase" evidence="7">
        <location>
            <begin position="34"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="523"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="640"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="757"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="812"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="710"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD43781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="832" mass="90741" checksum="28BAB801FDDD012C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q147</accession>
    <name>D3Q147_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron-sulfur cluster assembly accessory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019368.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4146"/>
    <dbReference type="EnsemblBacteria" id="ADD43797">
        <property type="protein sequence ID" value="ADD43797"/>
        <property type="gene ID" value="Snas_4146"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4146"/>
    <dbReference type="eggNOG" id="COG0316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069054_5_0_11"/>
    <dbReference type="OMA" id="YQLYFDE"/>
    <dbReference type="OrthoDB" id="1891602at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="1">
        <location>
            <begin position="14"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="118" mass="12666" checksum="D2BA894883D19350" modified="2010-04-20" version="1">MTETQTETDAPTGVALTDEAAAKVKALLEQEGRDDLRLRVAVQPGGCSGLRYQLFFDERSLDGDVVNTYDGFELVVDRMSVPYLAGASIDFVDKIDAQGFQIDNPNAGGSCACGDSFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1F2</accession>
    <name>D3Q1F2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021303.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6108"/>
    <dbReference type="EnsemblBacteria" id="ADD45732">
        <property type="protein sequence ID" value="ADD45732"/>
        <property type="gene ID" value="Snas_6108"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6108"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043786_0_0_11"/>
    <dbReference type="OMA" id="EYETIAW"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="337" mass="37361" checksum="B2545F240FEF16F1" modified="2010-04-20" version="1">MGIELIDVNDAAAVEQLLDVRLAAHQADEPDNPAPCRVHFRVSVAQPSDDEEIRFFGVRADDRVVGYAALHFPIKDNLHFAYADVFVHPEHRRQGLGRSLVEHVKTVTRDAGRKNINIDVVGVWENGPKRFEGGRALLESCGFKVALTSVNRHADITALDPAEEQRLLDESLAKSAEYETIAWHHRVPEELLPPLAQLNSIFLSQAPLGDLALEEEKLDADRMRKSGERSIARGIEVMGVVARRKGSTELAATSVIGVPTEPGDVGHQWITLVDPAHRGHRLGMRVKVENLRQLRVVRPKVTRICTDNADSNAHMIAINEALGFKAVDALYEYQADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1J5</accession>
    <name>D3Q1J5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0122</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0122"/>
    <dbReference type="EnsemblBacteria" id="ADD39843">
        <property type="protein sequence ID" value="ADD39843"/>
        <property type="gene ID" value="Snas_0122"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0122"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_22_0_11"/>
    <dbReference type="OMA" id="QYVELWV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041490">
        <property type="entry name" value="KstR2_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17932">
        <property type="entry name" value="TetR_C_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="204" mass="22577" checksum="DF54121EAFDF6993" modified="2010-04-20" version="1">MSLPMTTPKVINRSRREEILELAVELFAARGYHGVSMDDIGARAHITGPALYHHFKGGKEEMLAEALIPVSARLLAGGREHTAAHADDPRAALRALVTFHVDFALTSPAVIAVQLHELDRLPSEPRHRIRKLQRSYVEEWVGVLRRLRPELGDTDARVLAHAAFGLMNSTPFLGRDSLAERPRIAELLTEAALSALDPEHRSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1Y3</accession>
    <name>D3Q1Y3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017421.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2157"/>
    <dbReference type="EnsemblBacteria" id="ADD41850">
        <property type="protein sequence ID" value="ADD41850"/>
        <property type="gene ID" value="Snas_2157"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2157"/>
    <dbReference type="eggNOG" id="ENOG5030QVS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121293_0_0_11"/>
    <dbReference type="OrthoDB" id="2050869at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="191" mass="21568" checksum="D91531167E314E02" modified="2010-04-20" version="1">MSLSDELAKLVVEVTSPDGNIKAKLVAGEQLTVAFRPGTYARYDERGLEHQLSRLAMLAWTGYRRGFFEAKGRAEDISAKDAEKEHLNHWDANTRRYNEEMAQIVARGKSSGNVIRAQAKGLAFWKVEIRDGTLASMDEATFCAECVSVLAAVQRDSKNQEILLKDFYFGLNIPKSWRKKNPLRIERGVMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q267</accession>
    <name>D3Q267_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017505.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2244"/>
    <dbReference type="EnsemblBacteria" id="ADD41934">
        <property type="protein sequence ID" value="ADD41934"/>
        <property type="gene ID" value="Snas_2244"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2244"/>
    <dbReference type="eggNOG" id="COG1228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023620_0_0_11"/>
    <dbReference type="OMA" id="TRWIDDR"/>
    <dbReference type="OrthoDB" id="1456605at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="165"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="367" mass="39237" checksum="2A33DCB8967087D1" modified="2010-04-20" version="1">MTDSGPWHLRVVWLPDDTERDVYIDGDRLGFEPIPGATTIASSGYALPGLVDAHCHIGIKRGAIPIESLDEARELALTDRDAGVLAIRDAGSPFPYPELDNAVDLPRLVRAGRHLAPHRRYLRGVAIECTAEELPQRAAEQAKLGNGWIKLVGDWIDRDAGDLGPTYDASVLAAAIDAAHAAGAKVAVHTFSEEAVEAVVRAGVDSVEHGTGLSTELIDLMARNGTALVPTMINIATFDSIADQAQPKFPTYADHMRQLKAGFPDVVRQAHEAGVPIYVGTDAGGGIDHGLAAEEMLLLHERAGLDAGEVLSAASWGAREWLGFGGAKLEHGGEGFGDVVVYDADPRTDLRVVREPKRIVLRGNIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2B6</accession>
    <name>D3Q2B6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Snas_4199</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019420.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4199"/>
    <dbReference type="EnsemblBacteria" id="ADD43849">
        <property type="protein sequence ID" value="ADD43849"/>
        <property type="gene ID" value="Snas_4199"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4199"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016755_0_2_11"/>
    <dbReference type="OMA" id="HMVGDRM"/>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="8"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="340"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="438"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="141"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="178"/>
            <end position="185"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="45"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ADD43849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="461" mass="47879" checksum="E0025AE6B7211CE7" modified="2010-04-20" version="1">MSDPNAGYDVVILGSGSAGYACALRAAQLDLSVAIIEKDKLGGTCLHTGCIPTKALLHAGEVADSARHGEEFGVKTEGVSIDMAGVNAYKDGVVAKMYKGLQGLIKASKVTVIEGSGKLVGPNTVEVNGERVTGRNIVLATGSYSKSLPGLDVDGTKVITSEHALRLDKVPSSAIVLGGGVIGVEFASAWKSLGADVTIVEALPRLVAAEDADSSKMLERAFRKRGIKFKTGKGFESLKETAGGVSVTIAGGETIDAELLLVAVGRGPSTAGLGYDEQGVSMDRGFVLVNEHLQTNLPGVYAIGDIVPGVQLAHRGFGHGIFVAEHIAGLNPRPIDEAGIPKVTYSEPQVASVGYSEEAAKEKFGADVVVSYNYNLGGNGKSNILKTQGFVKLVSVKDGPVVGVHMVGANMGEQIGEAQLIYNWEAFPSDVAQLIHMHPTQNEALGEAHLALAGKPLHAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2E0</accession>
    <name>D3Q2E0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019444.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4224"/>
    <dbReference type="EnsemblBacteria" id="ADD43873">
        <property type="protein sequence ID" value="ADD43873"/>
        <property type="gene ID" value="Snas_4224"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4224"/>
    <dbReference type="eggNOG" id="ENOG50334RC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_537361_0_0_11"/>
    <dbReference type="OrthoDB" id="359108at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="507" mass="55099" checksum="ADAF2C39D1706788" modified="2010-04-20" version="1">MLDPRRLDATTPLWLPVAEQLVDVYRKTSAEAGLDYYQAHRAAKGIHAPLPDLAAETGNRDAVRTSLIVCGPVAIKHATGQGATLAEAVHIGETRAEAAAARHVLNGGRDSVHAAVDADAECLGFVRVTDADPCWLCAMQASRGPVFLSEVSAVLRRETTPEYAAFLRANPDGGRYRGKKFTGRRVPYHDGCQCTAEPLYSYDAPWPGTGREFDALWQDATKGRTGADARRAFRRAVAAASPTQSADARRRKRADARRAEAEQHPPLPEPDTDRAGTRSDVPPEEPAPAPEPDAAPAETGTGPGPLGDLSRLSDDELFALFGEHAADENAVAAITAEMDRRDVPDGGDVAQGVEELTPEQRRVEELVSQGWDWQDAYAEAHGVDADELDRQARAAEVDAHRYTGETRDEAVRRMYDEYVQVSYVAAEDATAGHMLSKAGRAADVNPLSLFSGTTARARKYASEDLLRWWSEHGRMTFTEYRAQVLGRETDRAAAAVTAMQSNGRDFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2F1</accession>
    <name>D3Q2F1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4235"/>
    <dbReference type="EnsemblBacteria" id="ADD43884">
        <property type="protein sequence ID" value="ADD43884"/>
        <property type="gene ID" value="Snas_4235"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4235"/>
    <dbReference type="eggNOG" id="COG5412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_284811_0_0_11"/>
    <dbReference type="OMA" id="GIMTILP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="634"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="673"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="699"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="724"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1089" mass="109920" checksum="43E505DE89670703" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2I1</accession>
    <name>D3Q2I1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ThiJ/PfpI domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019485.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4265"/>
    <dbReference type="EnsemblBacteria" id="ADD43914">
        <property type="protein sequence ID" value="ADD43914"/>
        <property type="gene ID" value="Snas_4265"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4265"/>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_1_11"/>
    <dbReference type="OMA" id="RVMEYDW"/>
    <dbReference type="OrthoDB" id="1459004at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049478" evidence="1">
        <location>
            <begin position="32"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="40"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="251" mass="26567" checksum="B093E0EB563814EB" modified="2010-04-20" version="1">MNSSRRTVLRAAVAGSLGVGLAASSSSPVAAREPGGDGPRIGILLYEGFSLLDPTGPAEVLSRVPGAEVVMIGERTGPVRCDTGQAALIADVTVDDMRDMDVLIVPGGSDEAVMAVFDNDRLRDWIVRVHKRTRFTTSVCTGAAILGHLGLLKGRRATTYWAGAEFLESVGATYVPERYVRDGKIITSAGVSAGQDMAYYLAGLLTDRRTGEALELALEYDPKPPFGTGDAQEASQELKDLALKLLKDSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2M2</accession>
    <name>D3Q2M2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_6150</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021344.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6150"/>
    <dbReference type="EnsemblBacteria" id="ADD45773">
        <property type="protein sequence ID" value="ADD45773"/>
        <property type="gene ID" value="Snas_6150"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6150"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_0_0_11"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="96"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="335" mass="36408" checksum="F6EDB3A44290F5D3" modified="2010-04-20" version="1">MLRFIVRRLLQLIPTLIGLSLLLFIWLRSLPGGPEAALLGDRATPERMAAIREQLGLNDSIWVQYGRFVKKLVQLDFGNSLQRGAGSVTEEFFRRFPATVELALTAMLIAIVVGIPLGYLAARRRGGFLDFGAVAGSLLGICVPVFFLGFLLKVFFAENLQMFPSAGRLTAGLEYNDITGLLVFDSLITGDFMVLSDALAHLILPGLTLASIPLAIIVRMTRASVLEVLGEDYVRTAESKGLKAKTIRTRHVLRNAMLPVVTTIGLLTGGLLSGAVLTETVFAFGGIGKFTADAIAARDYPTLNGFIMFIAVIYVLINLLVDVAYSVLDPRVRVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2N1</accession>
    <name>D3Q2N1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase domain protein hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021353.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6159"/>
    <dbReference type="EnsemblBacteria" id="ADD45782">
        <property type="protein sequence ID" value="ADD45782"/>
        <property type="gene ID" value="Snas_6159"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6159"/>
    <dbReference type="eggNOG" id="COG0546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_22_0_11"/>
    <dbReference type="OMA" id="AKYEPNA"/>
    <dbReference type="OrthoDB" id="1484726at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="202" mass="21427" checksum="599507927413DB21" modified="2010-04-20" version="1">MTTSPLVVGFDLDQTLYHTEPAIGATLRAVAAELGITFDVDRALTELGPPLDQLVGMQLDPDNTNAVVQRYREIYHIHGLPAAQLLPGARESLAAVRAAGGTSIVITGKNSRDATRHIEHNSLDVQHVIGWAWAQGKTDAMLEHGASIYIGDHPADIAAARAANAIALAVTTGTHGPDSFADADAILTSLTEFPDWLKTHLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q396</accession>
    <name>D3Q396_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0348</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015637.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0348"/>
    <dbReference type="EnsemblBacteria" id="ADD40066">
        <property type="protein sequence ID" value="ADD40066"/>
        <property type="gene ID" value="Snas_0348"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0348"/>
    <dbReference type="eggNOG" id="COG1403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114501_1_0_11"/>
    <dbReference type="OMA" id="AHLDHDP"/>
    <dbReference type="OrthoDB" id="1843957at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="124" mass="13765" checksum="052FFDAA7E59078B" modified="2010-04-20" version="1">MAPIRSEDRHRYPKDWKQISARIRHGRAAGRCECDGICGTGHTGRCPARQHHRHPVTGSKVVLTVAHLDRTPEHCDDDNLAAMCQRCHLAYDAEQHASNAARTRFRNATAGMEPLFGLDITTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3H3</accession>
    <name>D3Q3H3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-oxoadipate CoA-transferase</fullName>
            <ecNumber evidence="1">2.8.3.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2327</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.8.3.6" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017585.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2327"/>
    <dbReference type="EnsemblBacteria" id="ADD42014">
        <property type="protein sequence ID" value="ADD42014"/>
        <property type="gene ID" value="Snas_2327"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2327"/>
    <dbReference type="eggNOG" id="COG2057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069088_0_0_11"/>
    <dbReference type="OMA" id="CSYQAAV"/>
    <dbReference type="OrthoDB" id="1380130at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047569">
        <property type="term" value="F:3-oxoadipate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="253" mass="26440" checksum="D6114F0462E3616F" modified="2010-04-20" version="1">MSHTTEEMMTIAAARALPDGATCFVGIGLPSTAANLARHTHAPELVLIYESGTIGAKPARLPLSIGDGILAETADAVVSVPEIFNYWLQAGRIDIGFLGAAQIDRFGNINTTVIGADYQRPTVRLPGAGGAPEIAASSKEAIVVLRQSKRSFVDRVDFVTSAGFGTGPGFRQRHGLRGAGPTTVITDLGVYAPDPATSELVLTRLHPDVTVEQAKAACGWELSVPRDPARTPPPSEAELAALRALKPSPKAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3I0</accession>
    <name>D3Q3I0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017592.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2335"/>
    <dbReference type="EnsemblBacteria" id="ADD42021">
        <property type="protein sequence ID" value="ADD42021"/>
        <property type="gene ID" value="Snas_2335"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2335"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_10_11"/>
    <dbReference type="OMA" id="THWTNIP"/>
    <dbReference type="OrthoDB" id="961884at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="14"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="423"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="509" mass="54642" checksum="BD2E844ADC49D856" modified="2010-04-20" version="1">MSTLSLASVLAGSARRCGDHIGLIEGDKRITYSRLWAEALAQAAALERLGVRPGDRVALMCPNTVEFPRAYYAILAAGAVVVPVHLLLRAEETEYVLRDSGARLLLCHSACAEVGGQAARAAGVRMVTVGPQAPDLGADAHLEDVAEAGSPLPTFVTRAPGDPAVVFYTSGTSGQSKGAVLSHLNLIMNATICAFDTHDYRRDDIALGALPLFHTFGQSVSMNTLFRLGGTLVLMPRFDPAAAIELMVAENVTVFHGVPTMYRALTQAAAHASALPRLRLCLSGGASLPGPVLEEFNTTFDASIYEGYGLSETSPVATVNQPAYGTRVGTVGHPLWGVDVEIARAESEGIELLPTGELGEIVVRGHNVFNGYLDRPAESAKALVDDWFRTGDLGTKDDEGFVTIVDRVKDMIIRNGFNVYPSEVEEVLLRHPGVAEVAVIGLPDEECGEEVCAVVVADEDQVPTAEEVLEFGRERMGAHKYPRRVEFVKELPLGPSMKVLKRVLRDRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3T4</accession>
    <name>D3Q3T4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ketol-acid reductoisomerase (NADP(+))</fullName>
            <shortName evidence="8">KARI</shortName>
            <ecNumber evidence="8">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetohydroxy-acid isomeroreductase</fullName>
            <shortName evidence="8">AHIR</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ilvC</name>
        <name evidence="12" type="ordered locus">Snas_4354</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22068"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13493"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49256"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019572.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4354"/>
    <dbReference type="EnsemblBacteria" id="ADD44001">
        <property type="protein sequence ID" value="ADD44001"/>
        <property type="gene ID" value="Snas_4354"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4354"/>
    <dbReference type="eggNOG" id="COG0059">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033821_0_1_11"/>
    <dbReference type="OMA" id="RAMFSWL"/>
    <dbReference type="OrthoDB" id="188901at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00056"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00435">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014359">
        <property type="entry name" value="KARI_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="PTHR21371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="IlvN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000116">
        <property type="entry name" value="IlvC_gammaproteo"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8 9" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="8 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="10">
        <location>
            <begin position="3"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="11">
        <location>
            <begin position="184"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="26"/>
            <end position="29"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD44001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="336" mass="36543" checksum="794568C8CBD2315B" modified="2010-04-20" version="1">MAAEVFYDDDADLSIISQRKVAILGYGSQGHAHALSLRDSGVDVRIGLKESSKSRSKAEEEGLAVGTPAEVAAWADVIMVLVPDTVQADVYKTDIEPNLKQGDAIMFGHGFNIRYDLIQPPAGVDVAMVAPKGPGHVVRRQFNEGKGVPCLIAVEQDATGGAQALALSYAKAIGGTRAGVLTTTFTEETETDLFGEQVVLCGGVTELMRAGFDTLVEAGYQPEAAYFEVLHELKLIVDMVNEGGLSNMWYSVSDTAEYGGVTRGPRIITDETRAEMRRVLGEIQDGSFAKEWVAESKSYEQFNKLREDQKAHPIEKIGAKLRDMMPWVKRKITETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q482</accession>
    <name>D3Q482_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">5-oxoprolinase subunit A</fullName>
            <shortName evidence="1">5-OPase subunit A</shortName>
            <ecNumber evidence="1">3.5.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">5-oxoprolinase (ATP-hydrolyzing) subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pxpA</name>
        <name evidence="2" type="ordered locus">Snas_6351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-oxo-L-proline + ATP + 2 H2O = ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10348"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58402"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.5.2.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a complex composed of PxpA, PxpB and PxpC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LamB/PxpA family.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.9" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021538.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6351"/>
    <dbReference type="EnsemblBacteria" id="ADD45967">
        <property type="protein sequence ID" value="ADD45967"/>
        <property type="gene ID" value="Snas_6351"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6351"/>
    <dbReference type="eggNOG" id="COG1540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069535_0_0_11"/>
    <dbReference type="OMA" id="DRTYKQD"/>
    <dbReference type="OrthoDB" id="918580at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00691">
        <property type="entry name" value="PxpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005501">
        <property type="entry name" value="LamB/YcsF/PxpA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30292">
        <property type="entry name" value="PTHR30292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03746">
        <property type="entry name" value="LamB_YcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="254" mass="26853" checksum="A9BE4280A50E8C42" modified="2010-04-20" version="1">MRRTIDLNCDLGEGFGVWTLGDDEALLDIVTSANVACGFHAGDPSIMRAVCERAAARGVAIGAQVGYRDLAGFGRRNIDVEPRVLTDEVLYQLGALDAFALRAGDHVRYVKPHGALYNRIVTDSEQAAAVVAAVTAYDPKLAVLGLPGSRFLKLAAEAGLVTVTEAFADRAYTTEGRLVPRSRPGAVLHDAETIAGRVRRMAVDGRVVSIDGVVIDMTAQSVCVHGDTPGAVDIARRVRSALDEAGIHVSAFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q497</accession>
    <name>D3Q497_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmG</name>
        <name evidence="5" type="ordered locus">Snas_6366</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021553.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6366"/>
    <dbReference type="EnsemblBacteria" id="ADD45982">
        <property type="protein sequence ID" value="ADD45982"/>
        <property type="gene ID" value="Snas_6366"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6366"/>
    <dbReference type="eggNOG" id="COG0267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190949_0_2_11"/>
    <dbReference type="OMA" id="RYTTMKN"/>
    <dbReference type="OrthoDB" id="2034291at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="L33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_L33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018264">
        <property type="entry name" value="Ribosomal_L33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43168">
        <property type="entry name" value="PTHR43168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00582">
        <property type="entry name" value="RIBOSOMAL_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="56" mass="6694" checksum="AC40F636EA332B6B" modified="2010-04-20" version="1">MAKSGTDVRPKITMACVECKERNYITKKNRRNDPDRMELKKFCPRCNKHTAHRETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4I5</accession>
    <name>D3Q4I5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015716.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0429"/>
    <dbReference type="ESTHER" id="stanl-d3q4i5">
        <property type="family name" value="Aclacinomycin-methylesterase_RdmC"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40145">
        <property type="protein sequence ID" value="ADD40145"/>
        <property type="gene ID" value="Snas_0429"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0429"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_0_0_11"/>
    <dbReference type="OMA" id="SWPDALC"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="38"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="282" mass="30302" checksum="AB1B9DBEB6D36616" modified="2010-04-20" version="1">MRIKANGVELCVETFGAPEDPPVLLIGVTMLSWPDELCQALAGRYVVRYDLRDTGQSTFADPDAPGYDLRDLVSDASELLRALDLGPAHVVGMGVGGFIAQLLALDHPDRVASLTLISTRPVAPGPVDPDLPDHSPQMMQRLFGRAKPDWTDRDSVVDYMTGSARILSGTRGFDEQDARATAAAIFDRAEPTDKAQRASHLGIMFAAIDSKPRWRERLGEIKAPTLVVHGDEDPFFPHGNGVALAAEIPDASLLTLPGVGQGVPRAAWPTVVEALLRHTSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4I8</accession>
    <name>D3Q4I8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0432</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015719.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0432"/>
    <dbReference type="EnsemblBacteria" id="ADD40148">
        <property type="protein sequence ID" value="ADD40148"/>
        <property type="gene ID" value="Snas_0432"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0432"/>
    <dbReference type="eggNOG" id="COG2318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097062_2_1_11"/>
    <dbReference type="OMA" id="QCARSRE"/>
    <dbReference type="OrthoDB" id="2047691at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007061">
        <property type="entry name" value="DUF664"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04978">
        <property type="entry name" value="DUF664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="171" mass="19576" checksum="1BA4067337F22745" modified="2010-04-20" version="1">MTRTDTPTEWDERSTIMAMLDYARASARAKCEGLTDEQARTAPVATSPLTNLASLIGHLRWVEFDWIETVFLGIPDQGRTPWDDDPDDVDAEMTLALRTPLATLLSDYEQQCERYNKLIADHDLDERSRNPHPGRQPVTLRWILLHLVEEISRHNGHMDIVREIVDGQTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4W5</accession>
    <name>D3Q4W5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2462"/>
    <dbReference type="EnsemblBacteria" id="ADD42145">
        <property type="protein sequence ID" value="ADD42145"/>
        <property type="gene ID" value="Snas_2462"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2462"/>
    <dbReference type="HOGENOM" id="CLU_1155827_0_0_11"/>
    <dbReference type="OrthoDB" id="2039974at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="240" mass="26363" checksum="84FCDCE7EB838840" modified="2010-04-20" version="1">MAIVNRQPPRRPRRLDERAVAARIHRIRLRRASPGTTGWFVLPLMLVVLAIGVALLTLPIAYAFFGTDIPFVVNDAGTKAPPSFGDRAKAGALGLLCWVVFIAALWRPVRDTIAFRWPHRFASRRIALTPDGVWLARGNRVVEGLEWSQVQAVSVVEEWQSTTVPTELARPPFVEVFPVKAAKESASLLGSLIVNTTPPGPGIRGKRYLIRLDCEADDIRRLAHVLDAFAPGKRVSGGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q562</accession>
    <name>D3Q562_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase class-I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019682.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4466"/>
    <dbReference type="EnsemblBacteria" id="ADD44111">
        <property type="protein sequence ID" value="ADD44111"/>
        <property type="gene ID" value="Snas_4466"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4466"/>
    <dbReference type="eggNOG" id="COG0518">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054974_3_2_11"/>
    <dbReference type="OMA" id="FTIFEWH"/>
    <dbReference type="OrthoDB" id="1242215at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="PTHR42695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="46"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="241" mass="25986" checksum="79BC7B46E685C29B" modified="2010-04-20" version="1">MTQQRTRPTAIVVQNGPKGGPGRVGEWLAAEGIALDVVHGYQEPVPERLEHDAVIVLGGGYLPDADDKAPWLAATRTLVRQALDTDTPVLGICLGGQLLAHVAGGVVEGDVGAPENGSTPVTIRPQASDDPLFGSLPPTVPAIEHHVDAITALPPDAIWLAETDRCPYQAFRVGRSAWGTQFHPEIDPDRVRRWDPEPLREQGFDPEQVYAGADADDEVARAIWEKVTRRFATVVHDAARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5L1</accession>
    <name>D3Q5L1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6456"/>
    <dbReference type="EnsemblBacteria" id="ADD46071">
        <property type="protein sequence ID" value="ADD46071"/>
        <property type="gene ID" value="Snas_6456"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6456"/>
    <dbReference type="HOGENOM" id="CLU_1626057_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD46071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="163" mass="17793" checksum="C8969E3D71DC9FA4" modified="2010-04-20" version="1">MSINALFHPATPADIPAEVAQPKPGKESRKPVRTPELSIGHSSARAISAGTKTTAIVPLYRYPDVARLRSGDVLTFNVQARARRHRRSIDVTITDVCPHDFVGDIPACVEGHEASAINPDNPTWAHCLGYAANRGATPLSPRERSKLASRGWVVIDFTPVRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5N9</accession>
    <name>D3Q5N9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Membrane protein insertase YidC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Foldase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Membrane integrase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Membrane protein YidC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Snas_6484</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021670.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6484"/>
    <dbReference type="EnsemblBacteria" id="ADD46099">
        <property type="protein sequence ID" value="ADD46099"/>
        <property type="gene ID" value="Snas_6484"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6484"/>
    <dbReference type="eggNOG" id="COG0706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036138_3_1_11"/>
    <dbReference type="OMA" id="NFIYYPV"/>
    <dbReference type="OrthoDB" id="524437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="Membr_insert_YidC/Oxa1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="PTHR12428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="231"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="277"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="282"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="350"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ADD46099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="366" mass="41675" checksum="8C74783E79E7A3F9" modified="2010-04-20" version="1">MFTFHPLYIGISWVLLRWHDLWDLILGADPVPGALNTSWQWILAIVFLVVTIRIVLFPLFVKQIKSQRAMQRLQPKMKELQQRYKGDRETLQKEMMELYRTEKANPLMGCLPMLLQAPVFIALLWVLRRIDPDKYSNYAKTLYTWTEAQWDSAINAKLFGAPIWATFLTTQKDLKCSEHYDSCTTAATLNVQLVSGILIALMIVTTYLTTRQMILKTGWNADPQQRMIQKLMLYGIPVMLLFSGGIFPIGVVLYWVVNNAFSLGQQIWVLRKYPPPKTDTSPKADIKAKPGSKKYEEQLREKRDRAKAMAPKVGAKPKDPKKATSNAAEELKRKQEQAKAKAAQGPRPGAKPTKRKKGGATRGANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5S2</accession>
    <name>D3Q5S2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0506</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015792.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0506"/>
    <dbReference type="EnsemblBacteria" id="ADD40221">
        <property type="protein sequence ID" value="ADD40221"/>
        <property type="gene ID" value="Snas_0506"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0506"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_1_1_11"/>
    <dbReference type="OMA" id="WFRWEPR"/>
    <dbReference type="OrthoDB" id="1552415at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="6">
        <location>
            <begin position="16"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="251" mass="26284" checksum="A4BEB96B010CEE35" modified="2010-04-20" version="1">MNPTTTNATGPRIPAWLVLTGMELRLILRNRSMALTAIVMPLGFAGVILAMSDAATADLATMNLTMLAGFTVYMTATMTLAHHRAALFLKRVRSSPASTTGIVLGFATAPILLFVGQSLLFIAITGAVKGILPAQPLILVAAAVIGAVTCAALAFLTASFTKTPEAAHFTTMPGFAVLFGGLMWVLSTPPDEVTVPTLALPGTAVTQLLRYAWSGEGSIEMGLLWPAVASVTVAVLSCAVAARLFRWEPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5U8</accession>
    <name>D3Q5U8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="446470.Snas_0533"/>
    <dbReference type="EnsemblBacteria" id="ADD40247">
        <property type="protein sequence ID" value="ADD40247"/>
        <property type="gene ID" value="Snas_0533"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0533"/>
    <dbReference type="HOGENOM" id="CLU_3122935_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045825">
        <property type="entry name" value="RamS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19402">
        <property type="entry name" value="RamS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="50" mass="4830" checksum="24BF12EB1BD9AFDD" modified="2010-04-20" version="1">MALLDLQGLESPADLSATRGGSSGSGHSCPSNLSATLCGGTSGLSVLICH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5V2</accession>
    <name>D3Q5V2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kelch repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015822.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0537"/>
    <dbReference type="EnsemblBacteria" id="ADD40251">
        <property type="protein sequence ID" value="ADD40251"/>
        <property type="gene ID" value="Snas_0537"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0537"/>
    <dbReference type="eggNOG" id="COG3055">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_246178_0_0_11"/>
    <dbReference type="OMA" id="IAANGCC"/>
    <dbReference type="OrthoDB" id="138352at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF49452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048890" evidence="2">
        <location>
            <begin position="29"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1514" mass="160188" checksum="E6719F4D70F304DE" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q683</accession>
    <name>D3Q683_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6493 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
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                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017829.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2578"/>
    <dbReference type="EnsemblBacteria" id="ADD42258">
        <property type="protein sequence ID" value="ADD42258"/>
        <property type="gene ID" value="Snas_2578"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2578"/>
    <dbReference type="eggNOG" id="ENOG502Z9S7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016093_0_0_11"/>
    <dbReference type="OMA" id="DCAERSG"/>
    <dbReference type="OrthoDB" id="1365334at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045472">
        <property type="entry name" value="DUF6493"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20103">
        <property type="entry name" value="DUF6493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6493" evidence="1">
        <location>
            <begin position="221"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="927" mass="101948" checksum="C5A00F7682E0280B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6A6</accession>
    <name>D3Q6A6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2602"/>
    <dbReference type="EnsemblBacteria" id="ADD42281">
        <property type="protein sequence ID" value="ADD42281"/>
        <property type="gene ID" value="Snas_2602"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2602"/>
    <dbReference type="eggNOG" id="COG3238">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072587_0_0_11"/>
    <dbReference type="OMA" id="RWWMPLA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006750">
        <property type="entry name" value="YdcZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34821">
        <property type="entry name" value="PTHR34821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04657">
        <property type="entry name" value="DMT_YdcZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048898" evidence="2">
        <location>
            <begin position="33"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="333" mass="33778" checksum="3910038E791AEBC8" modified="2010-04-20" version="1">MTTVPRPRGAPSRLVVPVWAALALVVAGGACAAGQAAINGELGQRLDSPLTAAAISNSLGGVLFVVSLATVSRVREGLRRAWRQRLPLWMYTGGLFGAVYVFAGSLTVPLMGVALFTVAQVCGNTMGALGTDAVGLGPSGRLRVTRPRLAGAALAIVAIAVAQVGRDLATGLWWLVPFVVVIGAGLALQGAFNGRVNEVTGNPLSTGMVNFVAGTSVLYLIVGVVAVVDGLPLSRLPSEPWLYLGGPLGSLLVVFSMLAIKVIGVLRMALGILTGQLVGALVIDVVALGVTPSPWLVAGLVLTAAAVAITGRGKARAEATPDADISAAAAKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6B6</accession>
    <name>D3Q6B6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2612</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017862.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2612"/>
    <dbReference type="EnsemblBacteria" id="ADD42291">
        <property type="protein sequence ID" value="ADD42291"/>
        <property type="gene ID" value="Snas_2612"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2612"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="EGSRNVY"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="314" mass="33871" checksum="779E41574CB0E06F" modified="2010-04-20" version="1">MNSTPAIDIERLTKTYGSGARPAVDDVSLRIQPGTVFGFLGPNGAGKTTTIKIAAGLLAASAGTVRLNGYDVAARRSAAMAQIGAVLEGSRNVYWTLTAWQNLIYFGRLKGLRKAEARGQATELLTDLGLWDRRHDRVGDFSRGMQQKVAIAAALIADPPIVLLDEPTLGLDVAATRTVRNWIATLSEDRGKTILLTTHQLDVVAELCDRVAVIREGTIVADQATGELLSRFRRRDSYEVHIEGVPALPPLPGGFTAEESGDSTVIAGRVDDPRVVYQLLERLGERGIVLRSLAQAQPSLEDVFLSLVEEPAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6E5</accession>
    <name>D3Q6E5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M56 BlaR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_4543</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019759.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4543"/>
    <dbReference type="EnsemblBacteria" id="ADD44188">
        <property type="protein sequence ID" value="ADD44188"/>
        <property type="gene ID" value="Snas_4543"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4543"/>
    <dbReference type="eggNOG" id="COG0501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056335_0_0_11"/>
    <dbReference type="OMA" id="DEPLAYC"/>
    <dbReference type="OrthoDB" id="1707650at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="165"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="315" mass="33330" checksum="A159B66DA0E53676" modified="2010-04-20" version="1">MPTWVSIVVLGALAIALLGPIPAILERASWPSREPRAALVLWQAVGLAGGVSVLGVAIATALAPLGDTPWDAAMTWLATVWSGDLTGGLETFHLILLGMAMAITFRLAGVMPVTIWRTWTARRRHRDLVGLVSRPWPATRPGHGHVLEHPAAAVYCLPGGVGRDAPRVVFTTGALSALDDDELAAVLAHEHAHLVERHDLVALPFFAWVTALPWFPGVRRARSSVATLLEMVADDRAATQVSPATLASALARIGTAAAGRAATPVGAIAVDGGGVLQRVRRLLCPPDRSRRWRVSAYLLAAGLIVAPFLAITTIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6E8</accession>
    <name>D3Q6E8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Iron (Metal) dependent repressor, DtxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_4546</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DtxR/MntR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019762.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4546"/>
    <dbReference type="EnsemblBacteria" id="ADD44191">
        <property type="protein sequence ID" value="ADD44191"/>
        <property type="gene ID" value="Snas_4546"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4546"/>
    <dbReference type="eggNOG" id="COG1321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069532_0_0_11"/>
    <dbReference type="OMA" id="VARMEKH"/>
    <dbReference type="OrthoDB" id="2047422at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036421">
        <property type="entry name" value="Fe_dep_repressor_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022687">
        <property type="entry name" value="HTH_DTXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01325">
        <property type="entry name" value="Fe_dep_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47979">
        <property type="entry name" value="SSF47979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50944">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH dtxR-type" evidence="8">
        <location>
            <begin position="5"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="228" mass="25004" checksum="DB11FABB14F23035" modified="2010-04-20" version="1">MTTDLVDTTEMYLRTILELEEEGVTPLRARIAERLAQSGPTVSQTVARMQRDGLLNVLGDRHLDLTDLGRERAVSVMRKHRLAELLLVDVIGMSYEDAHDEACRWEHVMSDAVEQKVFELLNKPTRSPYGNPIPGLEALGSDAATTTFDPAERHLASAGLSGSFRVTRLCESVQTDAAVLHDLHSAGVNPGAVVDVKRRDDVIELRHDNVATSLSVQDASRVFVVPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6I3</accession>
    <name>D3Q6I3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemolysin-type calcium-binding region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019797.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4582"/>
    <dbReference type="EnsemblBacteria" id="ADD44226">
        <property type="protein sequence ID" value="ADD44226"/>
        <property type="gene ID" value="Snas_4582"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4582"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_457723_0_0_11"/>
    <dbReference type="OMA" id="TIETHYD"/>
    <dbReference type="OrthoDB" id="86247at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028208">
        <property type="entry name" value="Effector_pro_NleD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14891">
        <property type="entry name" value="Peptidase_M91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="639" mass="67449" checksum="FF5355CA08D36BFF" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6R4</accession>
    <name>D3Q6R4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_4664</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019878.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4664"/>
    <dbReference type="CAZy" id="GT51">
        <property type="family name" value="Glycosyltransferase Family 51"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44307">
        <property type="protein sequence ID" value="ADD44307"/>
        <property type="gene ID" value="Snas_4664"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4664"/>
    <dbReference type="eggNOG" id="COG0744">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006354_2_6_11"/>
    <dbReference type="OMA" id="AVQMPYI"/>
    <dbReference type="OrthoDB" id="652304at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="10">
        <location>
            <begin position="83"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="9">
        <location>
            <begin position="372"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD44307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="721" mass="77676" checksum="95D0AD74E75E34D5" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6R5</accession>
    <name>D3Q6R5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4665</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SURF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019879.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4665"/>
    <dbReference type="EnsemblBacteria" id="ADD44308">
        <property type="protein sequence ID" value="ADD44308"/>
        <property type="gene ID" value="Snas_4665"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4665"/>
    <dbReference type="eggNOG" id="COG3346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047737_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06662">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="PTHR23427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50895">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="256" mass="27712" checksum="526CDEB63F97BC11" modified="2010-04-20" version="1">MTRDYRFLISWRWLGLTLLGLALVATCVGLGIWQHDRYEQRAATNERIETAAADDTPAKASEVLSEDAEPGDDTLWTKVEATGEFDADAQILIRNRSVDGQNGYEVVTPLLLSDGTALLVDRGWVPPADSGATEAPKVPAPPEGSVTVTGRVRPSESPLGSVEKVSGTIQARSIDVDRISKHLDGPVLRGYITQDDPAKGFTAIPVPTQRAWQNFAYAYQWWLFAGMIPVGLVMIARREAGGGKPTSRRPSTVAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6S3</accession>
    <name>D3Q6S3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0608</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0608"/>
    <dbReference type="EnsemblBacteria" id="ADD40322">
        <property type="protein sequence ID" value="ADD40322"/>
        <property type="gene ID" value="Snas_0608"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0608"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="WPPEVTS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="255"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="351" mass="36913" checksum="CE95910A611DEFCA" modified="2010-04-20" version="1">MVIAGQAAAIAVSWGDDYWWFGAAVGAGVCVLALLRRRQRAWTAAAGLTAAGVAVAARWVAELPQEPSPAMALGLAVLTGSAVRTLPWRQAGAIVVAGFAVLAGALAPALPFVPAVVMVAAFVWAAGVAAGLSLRVADGRRRATAARVRQDERLELARELHDVVAHHISAIVLGTQAARLVVRRQPERGDEALAEIEAAGSDALASMRQVVGLLRDDRDGASAAGTLAELVERFAERGPRVDLRVTGDESRWPPEVASTVYRITREALTNVRRHAPRADTVTVRVDEAAAAIVAEISDDGPARARRSPGGYGLVGMRERVEALGGSLMAGPGDGRGWRVRATVPVRERAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6U2</accession>
    <name>D3Q6U2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015912.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0627"/>
    <dbReference type="EnsemblBacteria" id="ADD40341">
        <property type="protein sequence ID" value="ADD40341"/>
        <property type="gene ID" value="Snas_0627"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0627"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_13_0_11"/>
    <dbReference type="OMA" id="MSTVSWE"/>
    <dbReference type="OrthoDB" id="2045488at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="37"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="101" mass="10972" checksum="172CEACB4D60141F" modified="2010-04-20" version="1">MELRDMSELTSGISTEQRARIDAIKQEMIDAERGHELASLRKAQGLTQSQVAEAMGVTQGRISQIESGKTRLDTETMAAYLHAIGGELTITATVGRLSIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q731</accession>
    <name>D3Q731_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40430">
        <property type="protein sequence ID" value="ADD40430"/>
        <property type="gene ID" value="Snas_0718"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0718"/>
    <dbReference type="HOGENOM" id="CLU_1601691_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="166" mass="18504" checksum="1CCAA89FF17282A9" modified="2010-04-20" version="1">MSYPPQYGHPQRPQGYPQPPQGYPQQQYGYQYPPQQQRPGYAPPPQFQQRPPAYQPPAYQPAPKRRKNISWLGLVLVVVLGGGFFAVQMTKSEPNVGQCLASMDDRFIGGLEIVPCDGASAKFEVVNKQSGRGNPSVCLDHPDGESFSERGRRGKIYWEICAVPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7B8</accession>
    <name>D3Q7B8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Intradiol ring-cleavage dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2713</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017960.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2713"/>
    <dbReference type="CAZy" id="CBM12">
        <property type="family name" value="Carbohydrate-Binding Module Family 12"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42389">
        <property type="protein sequence ID" value="ADD42389"/>
        <property type="gene ID" value="Snas_2713"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2713"/>
    <dbReference type="eggNOG" id="COG3485">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027719_5_1_11"/>
    <dbReference type="OMA" id="YFPNEPR"/>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="SSF49482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049619" evidence="6">
        <location>
            <begin position="48"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-3" evidence="7">
        <location>
            <begin position="225"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="43"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="271" mass="29295" checksum="73C4B6E93D5CA679" modified="2010-04-20" version="1">MTGNPESPDERPGDAEPRRGITRKHLLNTAAVAVPASFLVGAAPAQADSDQSGKRLSPTPSCDDGDDPTPPQTEGPYFKPNSPERTTMLDGPGTRLVLTGIAFGLDCQRLPDVLLDFWMADTYGQYDNVTYRFRGHQYTAGDGSFTLTTIVPGLYPGRTRHIHVKAQAPGKPVLTTQLYFPGEPGNNTDPIFDARLLMDVRTVGSGKEASFEFVLNVDGGPGEPGGTWRSGTSYKAGDKVTYNGTQYQCQIAHTAQPGWEPPSTPALWRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7G1</accession>
    <name>D3Q7G1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, RpiR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2756</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2756"/>
    <dbReference type="EnsemblBacteria" id="ADD42432">
        <property type="protein sequence ID" value="ADD42432"/>
        <property type="gene ID" value="Snas_2756"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2756"/>
    <dbReference type="eggNOG" id="COG1737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055769_0_0_11"/>
    <dbReference type="OMA" id="QDLEHAP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05013">
        <property type="entry name" value="SIS_RpiR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000281">
        <property type="entry name" value="HTH_RpiR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035472">
        <property type="entry name" value="RpiR-like_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01418">
        <property type="entry name" value="HTH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51071">
        <property type="entry name" value="HTH_RPIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH rpiR-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="139"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="32007" checksum="A2855EC843AEA7A1" modified="2010-04-20" version="1">MVPGGENEHLRDDSVIQRIRELAPGLAPAERRVAEAIVETPRLVMTKSITELAGVGRTSETTVVRFCRRAGFRGYPDLRLAIATELGGDLARSGGTLAPGTDIDRDDTLEQLVRKVAFADVRAIQETVERLDLEALERVIDVLSTARRISLFGLGASAFAAQDLQHKLLRIDRMALAIPDSHLALGSAALLKPDDVAVGLSHSGQTAEVVECLTVARQHGAKTIAIVNAAPSPLTEQADLVITTRVRESRFRSGAMASRLAQLAVVDCVFLGIAQRSYDAAVEALTTTHETVHRGGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7G6</accession>
    <name>D3Q7G6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LmbE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018008.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2761"/>
    <dbReference type="EnsemblBacteria" id="ADD42437">
        <property type="protein sequence ID" value="ADD42437"/>
        <property type="gene ID" value="Snas_2761"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2761"/>
    <dbReference type="eggNOG" id="COG2120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049311_3_3_11"/>
    <dbReference type="OMA" id="EIVITHW"/>
    <dbReference type="OrthoDB" id="1282433at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016137">
        <property type="term" value="P:glycoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="228" mass="25399" checksum="3DB311504FF49F06" modified="2010-04-20" version="1">MSKKTYLAIGAHIGDMDLTAGPLLAKASLAGHRTCLLALTPGERGHPKLTPAEYKKQKIAEGRDFAERLGSEFKVLDHSDGFLPNTEEVHLEVADIIRDMKPDVVVAHWGGSFHSDHNNASEIAEMGRFYAGLPMKHDLPRHGVKDFVYAENWEDMDDFSPSMYVEIPKDAFDLWHDAIQVHAFARGETYGFMYIDYYSALMRAKGCLAGVKRACAFATKVDPGLKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Q2</accession>
    <name>D3Q7Q2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4752</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4752"/>
    <dbReference type="EnsemblBacteria" id="ADD44394">
        <property type="protein sequence ID" value="ADD44394"/>
        <property type="gene ID" value="Snas_4752"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4752"/>
    <dbReference type="HOGENOM" id="CLU_131550_3_3_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="2">
        <location>
            <begin position="4"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="57" mass="6321" checksum="A4F11A2552612093" modified="2010-04-20" version="1">MGPWRKSSRSNNAGGACVEARTTTGHFQLRDSKLGDSSPIFSLTDNDWKGFLAHVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q854</accession>
    <name>D3Q854_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PRK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016130.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0848"/>
    <dbReference type="EnsemblBacteria" id="ADD40559">
        <property type="protein sequence ID" value="ADD40559"/>
        <property type="gene ID" value="Snas_0848"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0848"/>
    <dbReference type="eggNOG" id="COG0572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067202_2_1_11"/>
    <dbReference type="OMA" id="WRIEYND"/>
    <dbReference type="OrthoDB" id="1793376at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRK" evidence="2">
        <location>
            <begin position="20"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="23252" checksum="D3A369E7CF79A67D" modified="2010-04-20" version="1">MSDTLAAAAALVPDAGQRRVLGLAGPPAAGKSTLARELVDGLNRRFGPGTAANVPLDGFHLSNAQLERLGVADRKGAIFTFDVDGYLALLRRLLAERSRDVYVPDYDRTLHEPIAARHVVAPGVRLVVTEGNYLASPAEGWREIADLAIELWYVETPDEERLRRLVRRHSSGGRGVRAARERAHHNDVPNGELVKVDRDRCARVITTGPWRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8C6</accession>
    <name>D3Q8C6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_2824</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018071.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2824"/>
    <dbReference type="EnsemblBacteria" id="ADD42500">
        <property type="protein sequence ID" value="ADD42500"/>
        <property type="gene ID" value="Snas_2824"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2824"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_9_11"/>
    <dbReference type="OMA" id="EPGSMTA"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="21"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="330"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="362"/>
            <end position="369"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD42500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="571" mass="60906" checksum="F88B58781983449E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8H0</accession>
    <name>D3Q8H0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2869"/>
    <dbReference type="EnsemblBacteria" id="ADD42544">
        <property type="protein sequence ID" value="ADD42544"/>
        <property type="gene ID" value="Snas_2869"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2869"/>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049344_7_1_11"/>
    <dbReference type="OMA" id="FEAWDPA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="58"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="275" mass="29572" checksum="26FCE69C49639BC4" modified="2010-04-20" version="1">MTTISSGTVPPTPSEPHRHRAMAESFGVDAERYDRTRPHYPDAMVTALVATAPGPDALDVGCGTGIEARQLQAAGWRVLGLDPDERMAAFARGTGVDVEVATFEDWDPRGRDFDAVIAATAWHWVDPVAGAAKAARILRPDGLLALIWNVGQPPSVVGRAFATACERMVPDLPGTLNAERPAVELYQAMFDKAADGIRATPDLSKPRQERWDWQQDYTREQWLDVLPTQGLLTRLAPEPLAEVLAEVGAAIDSLGGGFTMDYATVAVTATRTAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Y7</accession>
    <name>D3Q8Y7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0885"/>
    <dbReference type="EnsemblBacteria" id="ADD40596">
        <property type="protein sequence ID" value="ADD40596"/>
        <property type="gene ID" value="Snas_0885"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0885"/>
    <dbReference type="HOGENOM" id="CLU_1142045_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="243" mass="26035" checksum="A5DF14FB830CF941" modified="2010-04-20" version="1">MPAMPNADEDPVPLTVLGPSALENAWTDHGRGTGFAYAAAAVGGAAALGVITAASPGLSIPWQGRAALLAGAIALTVVAGYLLLLSRRGFQDAKRLAATTTRVQELIVGDTIEVHYLSGRVRTIRLADADFELQTFNTGSPARQKCELIAVDTDGEIIGLPLWDKPRPTSVNLGDSLAFHGPSIRKIDRDLDQLILALSKCSQPSAANVIEYLRSLMEARPTWRGWVRGKRSFGQWLGDQLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q955</accession>
    <name>D3Q955_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016235.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40664">
        <property type="protein sequence ID" value="ADD40664"/>
        <property type="gene ID" value="Snas_0953"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0953"/>
    <dbReference type="eggNOG" id="COG4319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150696_0_0_11"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="28"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="16117" checksum="CCB1367A7F9ABFF6" modified="2010-04-20" version="1">MTPPEQADPPRSRFDGLTPAEASRFAGRWLPAWTGNDPKRLAAFYTEDAFYADPAVPQGIQGQAVLLDYFAKLLGRFPDWVWTQTRATPLDGGFLNHWRADIPVRDRVVVANGVCTVQLRDGLIARNEVFFDRTELVAELTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q995</accession>
    <name>D3Q995_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2902</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018148.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2902"/>
    <dbReference type="EnsemblBacteria" id="ADD42577">
        <property type="protein sequence ID" value="ADD42577"/>
        <property type="gene ID" value="Snas_2902"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2902"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="VHMECVA"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="321" mass="34761" checksum="9F4896C73377D8D2" modified="2010-04-20" version="1">MDPEIRHLRAICAIADAGSLSKAARVLGISQPALSAQLKRIERIVGAELFVRARSGVVPTPDGERTLERARMLLVELDAFVGGLRHPNGRTRTALRLGSAHMECVGTMIELVRKALPEYEVRLRVEPSAVILAQAVTHDRMDLAVIGTMVDHDVRLAPPVEQRVLVPQVPVFVAIASGHALASRPEIALSELAGESWICPPGADDGSLASLRDACRHAGFEARVDYEAPSGGARQLIESGQGVRLVEPTASQEPGIAVRPLTGDPLHMRYRLAWRSGRFTDIELGRVYRAVGQAYTSHAVGSPVFAPWWQRHPEVHPLAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9B1</accession>
    <name>D3Q9B1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2918</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018164.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2918"/>
    <dbReference type="EnsemblBacteria" id="ADD42593">
        <property type="protein sequence ID" value="ADD42593"/>
        <property type="gene ID" value="Snas_2918"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2918"/>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049344_7_1_11"/>
    <dbReference type="OMA" id="TYSGHRA"/>
    <dbReference type="OrthoDB" id="1687413at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="4">
        <location>
            <begin position="31"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="264" mass="29680" checksum="AA8D01E9A09B68EA" modified="2010-04-20" version="1">MTDTDRERLRQTFTEDAELYDRARSGYPARMYEDLAELTGLKPDDHVLELGCGTGQATVSLARQGYRVTAVELGAGMATVARRNLASFPDVEVVNSSFEDWPLPSRPFDVVFSATAFYWIDPDVRMDKSADALRLGGALATVTTHHVKGGSEALFARFQDFYERFDPSTPPGLRLEPGDDIPCDTSDLESSERFGPPEFRRYEWDLDYSTQEYLDVLRTYSGHRALDPAQRDGLLGAIGDHIDRNGGRITKRYMTELRVTHRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9H1</accession>
    <name>D3Q9H1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_2979</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018224.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2979"/>
    <dbReference type="EnsemblBacteria" id="ADD42653">
        <property type="protein sequence ID" value="ADD42653"/>
        <property type="gene ID" value="Snas_2979"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2979"/>
    <dbReference type="eggNOG" id="COG0057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030140_0_2_11"/>
    <dbReference type="OMA" id="HETYKGE"/>
    <dbReference type="OrthoDB" id="944149at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004365">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="PTHR43148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="152"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="211"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD42653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="333" mass="35543" checksum="7D2EED776713949F" modified="2010-04-20" version="1">MTIRVGINGFGRIGRNFYRAVLQSGADIELVAFNDLGDAATTAQLLKYDSILGRLPYEVKANDGEITVNGKSIKVFAEKDPAKLPWGDVGADVVIESTGFFTDATKAKAHADNGAKKVIISAPAKNEDITIVYGVNHTDYDPAKHTVISNASCTTNCLAPMAKVLHENFGIERGLMTTIHAYTQDQNLQDGPHKDLRRARAAAINVVPASTGAAKAISLVMPELKGKLDGFAMRVPIPTGSATDLTFTASRETTVEEVNAAIKAAAEGPMKGVLSYTEDPIVSSDIVTDPASCIFDAGLTKVIGDQVKVVGWYDNEWGFSNRLIDMVKLVGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9K9</accession>
    <name>D3Q9K9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Leucyl-tRNA synthetase</fullName>
            <shortName evidence="9">LeuRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">leuS</name>
        <name evidence="15" type="ordered locus">Snas_4914</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020126.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4914"/>
    <dbReference type="EnsemblBacteria" id="ADD44555">
        <property type="protein sequence ID" value="ADD44555"/>
        <property type="gene ID" value="Snas_4914"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4914"/>
    <dbReference type="eggNOG" id="COG0495">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004427_0_0_11"/>
    <dbReference type="OMA" id="TFMVLAP"/>
    <dbReference type="OrthoDB" id="32262at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="PTHR43740"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="13">
        <location>
            <begin position="64"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1_2" evidence="14">
        <location>
            <begin position="293"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="12">
        <location>
            <begin position="803"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="549"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="723"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="726"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD44555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="950" mass="105734" checksum="AD568CF3DFA0A19B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9U7</accession>
    <name>D3Q9U7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020214.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5006"/>
    <dbReference type="EnsemblBacteria" id="ADD44643">
        <property type="protein sequence ID" value="ADD44643"/>
        <property type="gene ID" value="Snas_5006"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5006"/>
    <dbReference type="eggNOG" id="COG2230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026434_6_2_11"/>
    <dbReference type="OMA" id="QAEWAQK"/>
    <dbReference type="OrthoDB" id="1518440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="Mycolic_cyclopropane_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR003085-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="413" mass="45867" checksum="FA2C2D3B43DD6A34" modified="2010-04-20" version="1">MQLAEVFTRIVGNDPPVGFRAYDGSAIPAGPDAPVLDVRDQTALNYLASARRFELGLARAYITGAVDVAGDLYELMKKLWMLEVQLPKLELVKLWSALGGLKLLKRPPIPAREAHLSGRSHSKSRDADAISHHYDVGNDFYELFLGDSMAYTCAVYESHDTTLEQAQWAKHDLVARKLDLKPGMRLLDVGCGWGGMVRHAAKHYGVKALGVTLSKEQAEWAQKAIVDQGLQDLAEVKFLDYRDVPDDEYDVISSIGLTEHIGRENLASYFSSLYSKLKVGGRLLNHCITKPDSKGPAIARGGFIERYIFPDGALSGPGPLMTHMHDAGFEVQHAENLREHYALTLAAWEANLERNWDDAVKLVGLETARTWRLYLVGCRLGFEHNGIQLHQMLGVKLGDQLLPAMPLRPTWTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9U9</accession>
    <name>D3Q9U9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5008</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44645">
        <property type="protein sequence ID" value="ADD44645"/>
        <property type="gene ID" value="Snas_5008"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5008"/>
    <dbReference type="HOGENOM" id="CLU_2939559_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="60" mass="6696" checksum="A22D7CD30B4609EF" modified="2010-04-20" version="1">MWLHSKGVVELSEADIELAQVCEVADAMIRSRNLQEKLPAPDRKTLVDVVAAMTTRLAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Y3</accession>
    <name>D3Q9Y3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016266.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40695">
        <property type="protein sequence ID" value="ADD40695"/>
        <property type="gene ID" value="Snas_0985"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0985"/>
    <dbReference type="HOGENOM" id="CLU_2358332_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="96" mass="9768" checksum="59D324D3D27DAD1E" modified="2010-04-20" version="1">MNDLTADPPSIQSYGGNVNSIGQQIATDIDSRKGDLDATTDGLNTPAAFAGVVDAWSGICKGVSSEVVRAGDGTTLAGGDHDTNEVNQTSGMQNIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA54</accession>
    <name>D3QA54_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Snas_1056</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1056"/>
    <dbReference type="CAZy" id="GT51">
        <property type="family name" value="Glycosyltransferase Family 51"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40766">
        <property type="protein sequence ID" value="ADD40766"/>
        <property type="gene ID" value="Snas_1056"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1056"/>
    <dbReference type="eggNOG" id="COG0744">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006354_2_6_11"/>
    <dbReference type="OMA" id="VHGMGLA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049683" description="Peptidoglycan glycosyltransferase" evidence="9">
        <location>
            <begin position="28"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="11">
        <location>
            <begin position="57"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="10">
        <location>
            <begin position="350"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="10">
        <location>
            <begin position="477"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="252"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD40766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="705" mass="76382" checksum="2511CF982C5F81E0" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA78</accession>
    <name>D3QA78_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016361.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1080"/>
    <dbReference type="EnsemblBacteria" id="ADD40790">
        <property type="protein sequence ID" value="ADD40790"/>
        <property type="gene ID" value="Snas_1080"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1080"/>
    <dbReference type="HOGENOM" id="CLU_1569734_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="170" mass="19301" checksum="60F916069418A9BF" modified="2010-04-20" version="1">MSTVVDRLQRMTLNLTSPDGNLCATVDAERRARFHLRDETRFERYDAPTLSTQVKALLTTMNSGRELGIKRAYAADGREPAAVNGTHWDAAHRRFEAALATLELEGYSEDGLLLLQSGFDLSGYRVTIDRDDLPRTSPEQFLRELSGAYRDLLAHRRQRRAELLREHLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAB6</accession>
    <name>D3QAB6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018270.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3028"/>
    <dbReference type="EnsemblBacteria" id="ADD42699">
        <property type="protein sequence ID" value="ADD42699"/>
        <property type="gene ID" value="Snas_3028"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3028"/>
    <dbReference type="HOGENOM" id="CLU_121293_0_0_11"/>
    <dbReference type="OrthoDB" id="1733975at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="20556" checksum="2341F9B0EB1C27D5" modified="2010-04-20" version="1">MGVVAGQLAALTVTVSSPDARMRATVTAGKPRSFGFRPNTYRFYTEDRLGHQLARLATLAYIGHQRGVDRIHAENDMTVIRDPRQARDPAEATFVERSNSITVAGVGARKMVRFKTTGMLNWQCRIAEGTVRRLSEKEFVSEVSLAVNDVLGKTHSIAMLLKDEYRGRVLSHDVRERLIAELSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAN9</accession>
    <name>D3QAN9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020256.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44685">
        <property type="protein sequence ID" value="ADD44685"/>
        <property type="gene ID" value="Snas_5048"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5048"/>
    <dbReference type="eggNOG" id="ENOG50343FW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1936844_0_0_11"/>
    <dbReference type="OMA" id="FAHTAVQ"/>
    <dbReference type="OrthoDB" id="2083554at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049700" evidence="2">
        <location>
            <begin position="28"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="130" mass="14079" checksum="C38BC880EB2E2FAC" modified="2010-04-20" version="1">MRKVFAVFATLVGSVVAAISIATPAYAAFHDRVANPYLHTLLDALTLAIVTSPLWTAYLWGANRRRGLIALIAVVQVPVAVFSFVPIPDPALHAIALALSLTITVTSLWYVRRAAKLDAVEARTERITAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBC8</accession>
    <name>D3QBC8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016516.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1235"/>
    <dbReference type="EnsemblBacteria" id="ADD40945">
        <property type="protein sequence ID" value="ADD40945"/>
        <property type="gene ID" value="Snas_1235"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1235"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1980205_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="126" mass="13683" checksum="5C6461F5C2DBF884" modified="2010-04-20" version="1">MAVSSSLSVPHSHPVLPIGQSDWPTVQAPGYRLVTPTRPSRQERFCGGFADRTDPEAVVIRPGYLDGSWTKTSWTDQGVRDKVGATHLPLPELLQAFLAAGLRFESFGEGAEPTPVVFAVTARKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBD2</accession>
    <name>D3QBD2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">3-dehydroquinate dehydratase</fullName>
            <shortName evidence="7">3-dehydroquinase</shortName>
            <ecNumber evidence="5 7">4.2.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Type II DHQase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aroQ</name>
        <name evidence="11" type="ordered locus">Snas_3143</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes a trans-dehydration via an enolate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">Homododecamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the type-II 3-dehydroquinase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.10" evidence="5 7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018385.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3143"/>
    <dbReference type="EnsemblBacteria" id="ADD42814">
        <property type="protein sequence ID" value="ADD42814"/>
        <property type="gene ID" value="Snas_3143"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3143"/>
    <dbReference type="eggNOG" id="COG0757">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090968_1_0_11"/>
    <dbReference type="OMA" id="AYTHYSY"/>
    <dbReference type="OrthoDB" id="1872106at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00466">
        <property type="entry name" value="DHQase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00169">
        <property type="entry name" value="AroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001874">
        <property type="entry name" value="DHquinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018509">
        <property type="entry name" value="DHquinase_II_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036441">
        <property type="entry name" value="DHquinase_II_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21272">
        <property type="entry name" value="PTHR21272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01220">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001399">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52304">
        <property type="entry name" value="SSF52304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01088">
        <property type="entry name" value="aroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01029">
        <property type="entry name" value="DEHYDROQUINASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 7 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 9">
        <location>
            <begin position="100"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7 8">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7 10">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD42814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="145" mass="15910" checksum="CAF14D3BFB507FB4" modified="2010-04-20" version="1">MTVLVLNGPNLNRLGTREPLIYGSQTYADLERLCRDTGDKLGLAVDVRQTNAEHEMLEWLHTAADDVDDVVLNAAAWTHTSVAIGDACAALTGRLIEVHISNVHKRETFRHHSYVSAHADGIIVGCGFDGYRLALEHLAAVPREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBK1</accession>
    <name>D3QBK1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3213"/>
    <dbReference type="EnsemblBacteria" id="ADD42883">
        <property type="protein sequence ID" value="ADD42883"/>
        <property type="gene ID" value="Snas_3213"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3213"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042273_0_0_11"/>
    <dbReference type="OMA" id="WITIGAW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="432" mass="44452" checksum="9885F62743A8F897" modified="2010-04-20" version="1">MSLIPSAYRPVLANRVFRRLIGGFGVSYLGDGMSFVAVAWLAIELAPPGTAGLWVGGAVAAYTLPGVVGAMVFARWLRRIPAKRLLLIDNVVRGVFLGAIPLAWSTGLLTPTLYVLLLAGSSLLHAWGNAGKYTLLAELLPPPQRLAANTLVSTLNFAATIAGPAIAGVLVTYVSSALVLGLDAATYVFLAVLVARTRLPASAPAAPVETAAARGGLALLRSHPALLGLLALTWFFNFLYGPVEVALPLHVTDDLHAPGTLLGAYWMLFGIGAVAGGLAVGALKRLPLWPVTVAIVIGWGALLLPFGLAAPTLVTIAAFTLGGAIYGPFVALSVTLMQTTSPPQHLAAMLAARSAVLLTASPLGTALGGPLTTALGPRSTLGASGLATVVVGVAAAILLLAWRTRRPEPLPAFATSPRGRGHDDHDSRSTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBL4</accession>
    <name>D3QBL4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-dependent DNA helicase, RecQ family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3226</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018467.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3226"/>
    <dbReference type="EnsemblBacteria" id="ADD42896">
        <property type="protein sequence ID" value="ADD42896"/>
        <property type="gene ID" value="Snas_3226"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3226"/>
    <dbReference type="eggNOG" id="COG0514">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1040">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001103_5_0_11"/>
    <dbReference type="OMA" id="RLREDQW"/>
    <dbReference type="OrthoDB" id="54580at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="31"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="232"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="691" mass="74731" checksum="15148BBCD4337EE2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBX6</accession>
    <name>D3QBX6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5231</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020436.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5231"/>
    <dbReference type="ESTHER" id="stanl-d3qbx6">
        <property type="family name" value="Proline_iminopeptidase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44865">
        <property type="protein sequence ID" value="ADD44865"/>
        <property type="gene ID" value="Snas_5231"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5231"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_9_3_11"/>
    <dbReference type="OMA" id="ISRLWAS"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="70"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="293" mass="30592" checksum="C1697162F42D3549" modified="2010-04-20" version="1">MTRKTISTSIAIVGCVLAGVGLVGCDGSGLDEAGEEFKAELFTGTDTFTIGDHQVNVSCSGSPTSDGPIVLLLHGGGDDLTKLADFQKQISKNSRVCSYDRLGAGKSDKPDGEQDYASVGKTLTGVIDTFANGDPVVLVGHSMGGLIAARYAPDNKDKVAGMVLLDATSPTAVADLKQRIPEDATGEAAELRAQTLAIYGGENPEKLVFTDGKVKSAGDIPVRVIQHGKQYLAAVPEYGPGLEDDWTAGQKDWLNVSSDSELDTAKDSGHYIYVDEPDAAVEAVKDVASRAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUB8</accession>
    <name>D3PUB8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Cytidine deaminase</fullName>
            <ecNumber evidence="6 11">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Snas_1356</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 11">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>2'-deoxycytidine + H(+) + H2O = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>cytidine + H(+) + H2O = NH4(+) + uridine</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="6 11"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016635.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1356"/>
    <dbReference type="EnsemblBacteria" id="ADD41064">
        <property type="protein sequence ID" value="ADD41064"/>
        <property type="gene ID" value="Snas_1356"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1356"/>
    <dbReference type="eggNOG" id="COG0295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097262_0_0_11"/>
    <dbReference type="OMA" id="LTHFTCV"/>
    <dbReference type="OrthoDB" id="1895660at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047844">
        <property type="term" value="F:deoxycytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="12">
        <location>
            <begin position="6"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD41064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="132" mass="13766" checksum="FFE418108E6B188E" modified="2010-04-20" version="1">MDIDDAMWERLREAAVDAAKNAYVPYSHYPVGAAALVDDGRIVAGCNVENASFGLTLCAECGLVSRLFATGGGRLRAMACVDGKGEALTPCGRCRQLLHEHGGPDCLIDASPAPVRLGELLPGAFGPGHLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUF6</accession>
    <name>D3PUF6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Molybdopterin biosynthesis MoaE protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3301"/>
    <dbReference type="EnsemblBacteria" id="ADD42969">
        <property type="protein sequence ID" value="ADD42969"/>
        <property type="gene ID" value="Snas_3301"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3301"/>
    <dbReference type="eggNOG" id="COG0314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069141_1_0_11"/>
    <dbReference type="OMA" id="SEWKGHQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00756">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="SSF54690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="227" mass="25170" checksum="351E0F25DDD789F9" modified="2010-04-20" version="1">MKINVFYFGYIRERITHRRSEELDIPDDTTMRGLFETLCANYPGLDKLTAHMRIALNENLSCPEERLSNGDEVALIPPVAGGSDRYCRVTDEQLDLNEIVDAVSGPSRGGIVTFIGKVRDNSDGKKVTAIEYEAYRSMAISSLTDIITRCEAVAEDVRVAVAHRTGILDVGETVVIIAAAGPHRAEAFQAARSCAELMKWETTIWRKEIRPDGEEWIGVPCDLDIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUF9</accession>
    <name>D3PUF9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epoxide hydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3304</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018543.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42972">
        <property type="protein sequence ID" value="ADD42972"/>
        <property type="gene ID" value="Snas_3304"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3304"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_1_11"/>
    <dbReference type="OMA" id="EWCERYY"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033961">
        <property type="term" value="F:cis-stilbene-oxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EHN" evidence="4">
        <location>
            <begin position="3"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="387" mass="43332" checksum="98BB2EBF68C84C59" modified="2010-04-20" version="1">MSVTPFRVDTAPAVLDDLRDRLRATRWPEPETVDDWSQGVPLDYLRSLCEYWAEQYHWPTRQARLNTWPQYRTTVDGLGIHFIHARSPHPDAMPLILTHGWPGSVVEFTKVLGPLTDPVAHGGRAADAFHVVCPSLPGYGFSDKPPRTGWGVERIADTWAELMARLGYRRFGAAGSDWGTSISTLLALRHPELLTGIHLVPPLAAPDTSDTFTDAERDALARLKTRQATGDGYSVQQSTRPQTIGYGLVDSPVALCAWLVEKLWEWTDHDGDLHSVLSRDEVLDNIMLYWLPGTGASAARLYWESIRTIQSWFTESTPDTIAVPAGCSVFPAELPHPSRRWAKRRFTDIRYWGEPSRGGHFAAFEQPESFVAELRAFFSLVRGGEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUM0</accession>
    <name>D3PUM0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018604.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3369"/>
    <dbReference type="EnsemblBacteria" id="ADD43033">
        <property type="protein sequence ID" value="ADD43033"/>
        <property type="gene ID" value="Snas_3369"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3369"/>
    <dbReference type="eggNOG" id="COG0084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067079_0_0_11"/>
    <dbReference type="OMA" id="DEAQQGY"/>
    <dbReference type="OrthoDB" id="1139523at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006764">
        <property type="entry name" value="SAM_dep_MeTrfase_SAV2177_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04672">
        <property type="entry name" value="Methyltransf_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017393">
        <property type="entry name" value="MTase_SAV2177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="265" mass="29615" checksum="BBAC96DE17D1EB9B" modified="2010-04-20" version="1">MTDQSPPNIRTDIPHSARIWNYWMGGKDNYKIDRTVGDMSLRIDPGIATMATESRRFLMRTVSYVTSTGRMRQFLDIGTGLPTMQNTHEVAQKRAPESKVVYVDNDPAVLAHARALLTSTSDEGVTDYIDRDFHDPDQIIAEARNILNFKKPIAVMFMGVLGHAESVKEQQRIVSTVMDAVPSGSYLIYWDGTTDSDAYVKLCEEYAKTGGAPYIPRSRDEIRAVFDGLEMVDPGFVSITEWHTNEADIEDSEPISAYGGVARKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUV2</accession>
    <name>D3PUV2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5342</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020547.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5342"/>
    <dbReference type="EnsemblBacteria" id="ADD44976">
        <property type="protein sequence ID" value="ADD44976"/>
        <property type="gene ID" value="Snas_5342"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5342"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107158_0_0_11"/>
    <dbReference type="OMA" id="HLLMTGW"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="198" mass="20652" checksum="9A21A2395B101314" modified="2010-04-20" version="1">MPRGVAIPEVRQQLFAAVEQLIVRDGPGKLSGRAVTGAAGVATGLLYSHFRDLDDFLVGYAVDRAFQISANARTLPDKAGTNTVARNLSDTLLATPFGSARALTRLLVARPDLVDGVASVLGDGNTGIDAIETATAAYLDAERKLGRVAAATDVEALARALAGTLHHLVLTADESDIPALIERTVTALAEGMVRPPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUW5</accession>
    <name>D3PUW5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="7">6.3.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">D-Ala-D-Ala ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">D-alanylalanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ddl</name>
        <name evidence="11" type="ordered locus">Snas_5356</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020560.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5356"/>
    <dbReference type="EnsemblBacteria" id="ADD44989">
        <property type="protein sequence ID" value="ADD44989"/>
        <property type="gene ID" value="Snas_5356"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5356"/>
    <dbReference type="eggNOG" id="COG1181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039268_0_1_11"/>
    <dbReference type="OMA" id="IPYVGCD"/>
    <dbReference type="OrthoDB" id="764798at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000291">
        <property type="entry name" value="D-Ala_lig_Van_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011127">
        <property type="entry name" value="Dala_Dala_lig_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01820">
        <property type="entry name" value="Dala_Dala_lig_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01205">
        <property type="entry name" value="D_ala_D_alaTIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00843">
        <property type="entry name" value="DALA_DALA_LIGASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 7 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="137"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR039102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD44989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="346" mass="37719" checksum="A9FF6830BDF2E731" modified="2010-04-20" version="1">MAKSKVGIVFGGACEENPVSVKSAQEVARNLDTDKYEVLYIGITKTGDWLLCDSPDTGWETTKNRPAVLSPDRNVHGLLVLENGKYETIRLDLVFPVLHGKLGEDGAIQGLLELSGIPYVGCDVQTSALCMDKSLTYLVAQHAGITTPQYWIVTANKDIEPDRLPYPVVVKPARSGSSFGVNKVTHEEELQTAIDTARQYDSKVLIEEAIVGTEVGCSILGERYGLVAGEVDQINVSQGIFRIHQENNPESGSENSTITVPADISLESRSLVQETAKTLYRALGGKGLARIDFFLKEDGTLVLNEVQTLPGMTSYSRYPRMMAAAGIPMADLIDRMVSLTLNGKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUW8</accession>
    <name>D3PUW8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020563.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5359"/>
    <dbReference type="EnsemblBacteria" id="ADD44992">
        <property type="protein sequence ID" value="ADD44992"/>
        <property type="gene ID" value="Snas_5359"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5359"/>
    <dbReference type="eggNOG" id="COG1876">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104140_1_0_11"/>
    <dbReference type="OMA" id="YANEPWH"/>
    <dbReference type="OrthoDB" id="1593541at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003709">
        <property type="entry name" value="Pept_M15B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02557">
        <property type="entry name" value="VanY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VanY" evidence="2">
        <location>
            <begin position="48"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="175" mass="19308" checksum="041D208CEF5A2F30" modified="2010-04-20" version="1">MTYREPTQTAPRIPRSTLSAAHRTLGEAHGAVPANATVFDTHLPAIANLNPDLLNALHQAATDAAHHGITFTVNGGWRSPEYQQHLLQEAITTYGSATEAARWVATPDTSPHVSGHAIDLGPTKTTRWLSTHGSKYGLCQIFDNEPWHYELRPEAITHGCPPRYPDPSHDPRMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV10</accession>
    <name>D3PV10_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Magnesium chelatase ChlI subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5402</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5402"/>
    <dbReference type="EnsemblBacteria" id="ADD45034">
        <property type="protein sequence ID" value="ADD45034"/>
        <property type="gene ID" value="Snas_5402"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5402"/>
    <dbReference type="eggNOG" id="COG0606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026145_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048610" evidence="1">
        <location>
            <begin position="28"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Mg_chelatase" evidence="2">
        <location>
            <begin position="194"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Mg_chelatase_C" evidence="3">
        <location>
            <begin position="404"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="510" mass="53612" checksum="E86D0BF18DE98E02" modified="2010-04-20" version="1">MESTVNVGVAHTVAMIGLTATPVSVTASNSAGGSGFTMPQLPDYLADTTTSGIFAAWNNSDLPWPGGAVEIRFDFTPGVSGLGGCELAIAVAVARAAGLAPHDSPPAPTRMYAQLGIDGSLRATRGARPAAFTASTCGDNGVIVAAADHADVGDITGIAIRPAADLRGALRQLRSPTASAKAPTPPSEPLPKVDLHDILGLVQARHGLEIAAAGGHHMILLGAPDAGAVMLAERLPGILPPLTQHQADQVADIRSLAGQPYVGPGLTPPYSAPHHSSTMAAMVGSSTMIPRPGAISQAHNGVLFLDEAAEFRRDVLDTVLPAVAHQHLLITRYGDTIRLPARLHLVMASGMCPKDHPRRDCNCGPAARRYLHRLAGRLMDHVLIRIQLPDPPPYDELCQQSRGDSSATVRARVIAARRAAGERWSGRGADLTNQDVPVSLLRSPRFRLSATTMAPMTDRFADRTIPVRHETRLLRLAWTLADLDGTNSPCVDHVADAMRLGGFDALGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV19</accession>
    <name>D3PV19_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016643.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1365"/>
    <dbReference type="EnsemblBacteria" id="ADD41072">
        <property type="protein sequence ID" value="ADD41072"/>
        <property type="gene ID" value="Snas_1365"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1365"/>
    <dbReference type="eggNOG" id="COG3876">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033227_1_0_11"/>
    <dbReference type="OMA" id="YIWTLYD"/>
    <dbReference type="OrthoDB" id="1439085at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033922">
        <property type="term" value="F:peptidoglycan beta-N-acetylmuramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008302">
        <property type="entry name" value="NamZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42915">
        <property type="entry name" value="PTHR42915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07075">
        <property type="entry name" value="DUF1343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016719">
        <property type="entry name" value="UCP016719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049484" evidence="1">
        <location>
            <begin position="29"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="418" mass="46672" checksum="A44941E00FDA5D2C" modified="2010-04-20" version="1">MRRRNVLAASAAVTTAGLLAGSAPAAHARNGRRVRTGFANLAASGYRELRGQRVGIISNPTGITSDLSHEVDVMHFDSDVDLRAVFGPEHGFRGTSQAGQGEDFFEDPKTGLPVYNAYNDPQKMKDYFAERELETVVFDIQDVGSRFYTYIWTMYLAMDAAAQAGCRFVVLDRPNPTTASNAYGPILHEKFATFVGLKPISQRHGMTVGELAELFNGEFLDNAVDLTVVEMSGWRRRMSFDETGLPWVPPSPNMPQIGTARLYPGTCLFEASALSEGRGTTLPFQLIGAPDIDHRWEEALNKQKIPGVRFREAYFVPTFSKWSGKTCGGVEVQVTDYDRFDPIRTALAMIITQREVFPKYGWRTESDPNAHPWIDKLTGSAQVRKAIEAGADVDEVMEGWKSELDDFRDVRAEYLRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV30</accession>
    <name>D3PV30_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1376</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1376"/>
    <dbReference type="EnsemblBacteria" id="ADD41083">
        <property type="protein sequence ID" value="ADD41083"/>
        <property type="gene ID" value="Snas_1376"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1376"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_5_1_11"/>
    <dbReference type="OMA" id="AYGLFFY"/>
    <dbReference type="OrthoDB" id="1425840at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="27"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="167"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="34368" checksum="40EFB896D4A76A0F" modified="2010-04-20" version="1">MVMSTTSRGTERSVSSGGIFLVVALGIVYIVWGSTYLAIRIMVEDMPPLLSAGARFMLAGAVLAAILAARGGLARLAVTRAELLSCAALAMLLPVLGQGSVTVAENGGAPSGLTALLVAVVPLWVLLYRTLSGQRPARLTVYGVLLGFAGLVLLLVSNGVDADFPFWTMILVVLATMSWAFGSWYQPRLKLPRDPFVLTVYEMLIGGAVLMVAGFGGGETIDLGAYSSRSWMAWVYLVVFGSLIAFSAYVWLLHSAPVSLVATYAYVNPVVAVALGWLVLSEDVTTPIVVGGIVVVLAVAVVAGAERPRRTPRPNPEPTPEATTCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVB4</accession>
    <name>D3PVB4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016738.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1463"/>
    <dbReference type="EnsemblBacteria" id="ADD41167">
        <property type="protein sequence ID" value="ADD41167"/>
        <property type="gene ID" value="Snas_1463"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1463"/>
    <dbReference type="eggNOG" id="COG1247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1728173_0_0_11"/>
    <dbReference type="OrthoDB" id="1593819at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="152" mass="16811" checksum="B967E9C5D6AB7E9E" modified="2010-04-20" version="1">MSQVIREAEESDLPGIVGFEIDIARISFGDEAITDPAVHEKRVRSSLGKAGEITLVAGQPGTEPLGWAWLSRRTNSLTGARYGNFRSLAVAEHPERAETGERLLDEVIARCRADGIDELVGKVHADNLAMRALYRKFDFEAVHLTMRKRLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVC5</accession>
    <name>D3PVC5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016749.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1474"/>
    <dbReference type="EnsemblBacteria" id="ADD41178">
        <property type="protein sequence ID" value="ADD41178"/>
        <property type="gene ID" value="Snas_1474"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1474"/>
    <dbReference type="eggNOG" id="ENOG50348RK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068054_0_0_11"/>
    <dbReference type="OMA" id="HPEESAM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="294"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="380" mass="41126" checksum="5AC68D6AF2BED06D" modified="2010-04-20" version="1">MTENPDATTETETETETPSELERRFRRLLRAYPYWYRRHRGEELLGTLLDACGEDQDRPSRRQRRDILRSGLACRLRVRGGKAGVVLAVFLALMAAVAGSWIGARLGWVGAPDPPSAAEATAVAAEAFDGRKPDEVHGDDAPFAHGMEYATLTKSDFGQWTELAVFGGDSYRRAHQVASYEKSLSGEEWAAMTARVTANLEAAGWRVTYEDRTDGDTDFGTVTAVRDGQVVTVDGADDWPDVGPWIEVTVVHTVPAGQSAGLVVGAGLGLLAGWLFGVRIAWQWTVVTPRRRTLAMGLLFTSMPFGFGILLIAVAASGLSLQAAPTDIVQPPWYPLMNLPFRPLCLITAVLVLAAVLVAMLPGRRADPRVGPARQDAAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVH8</accession>
    <name>D3PVH8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018663.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3428"/>
    <dbReference type="EnsemblBacteria" id="ADD43092">
        <property type="protein sequence ID" value="ADD43092"/>
        <property type="gene ID" value="Snas_3428"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3428"/>
    <dbReference type="eggNOG" id="COG0394">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081551_1_0_11"/>
    <dbReference type="OMA" id="DCCRGRP"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="3"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="228" mass="24680" checksum="D000E4839A898CD9" modified="2010-04-20" version="1">MLIESDSVERRARVHAALGEPVRLRIVDALTLGDVSPQELERLVGMPSNLLAHHLKTLVDAGVVTRSRSEADRRRTYLRLVPEAVAGLQVSPRVVASRVVFVCTRNTARSQLAEALWRQHSQVPAASAGTDPAARVHPKAVAVARRHGLRLPPSGTAHVSDVVVEGDLVIAVCDNAHESMAVEAARWHWSVPDPVPVGTDEAFESAFADIDRRIDRLAPMLTVATGMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVL7</accession>
    <name>D3PVL7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transketolase central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018702.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3467"/>
    <dbReference type="EnsemblBacteria" id="ADD43131">
        <property type="protein sequence ID" value="ADD43131"/>
        <property type="gene ID" value="Snas_3467"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3467"/>
    <dbReference type="eggNOG" id="COG0022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012907_1_1_11"/>
    <dbReference type="OMA" id="EHVQLYN"/>
    <dbReference type="OrthoDB" id="900125at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="1">
        <location>
            <begin position="16"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="335" mass="35419" checksum="82BCB424B5E46772" modified="2010-04-20" version="1">MTGTEPATTEARTVTLTYREAMRDALRRALADEPVFLIGEDVGQYGGAFGVTLGLLEEFGPERVIDTPLSESGFVGAGIGAALGGTLPIVEVMTVNFSLLALDQILNNAATLSHMSGGRLHVPLVIRMTTGAGRQLAAQHSHSLEGWYAHIPGLRILAPATVEDARGMLAPALADPDPVLIFEHGSLYNDKATLPATPVPVSIDTAAIRRPGTDATVIGYGGTLATALSAADQLATEGIQAEVIDLRSLRPLDDATIMESVSRTHRAVIVDEGWRSGSLAAEISARITEQAFYDLDAPVERVCSAEVPMPYARHLEQAALPRPSDVAASVRRTVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVZ4</accession>
    <name>D3PVZ4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020686.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5484"/>
    <dbReference type="EnsemblBacteria" id="ADD45115">
        <property type="protein sequence ID" value="ADD45115"/>
        <property type="gene ID" value="Snas_5484"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5484"/>
    <dbReference type="eggNOG" id="ENOG5031XS9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1260816_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="219" mass="23081" checksum="FE0BF55640132EB5" modified="2010-04-20" version="1">MPSSPGKGGGHHRGSHRGPARGPQLLKAGGLLLAVALLLAAVGFGIVWTTDSQTSEPGKFKADRVKDLCDAVNAEGIQKFAPKEDDRQSDSDKKQNPAKFTCELRFTSGEESTSYQAITLSVDARVAATVGDAEKAFEGVVDYEKSRGFAVDKSSEGDQAAVVPKANTDPQECRAHIRSSNAVLSAELTVSGSQLSCAKEGVELLLETGTSTLDVMRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW09</accession>
    <name>D3PW09_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytokinin riboside 5'-monophosphate phosphoribohydrolase</fullName>
            <ecNumber evidence="1">3.2.2.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>9-ribosyl-trans-zeatin 5'-phosphate + H2O = D-ribose 5-phosphate + trans-zeatin</text>
            <dbReference type="Rhea" id="RHEA:48564"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16522"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:87947"/>
            <dbReference type="EC" id="3.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + N(6)-(dimethylallyl)adenosine 5'-phosphate = D-ribose 5-phosphate + N(6)-dimethylallyladenine</text>
            <dbReference type="Rhea" id="RHEA:48560"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17660"/>
            <dbReference type="ChEBI" id="CHEBI:57526"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="EC" id="3.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.n1" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020701.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5499"/>
    <dbReference type="EnsemblBacteria" id="ADD45130">
        <property type="protein sequence ID" value="ADD45130"/>
        <property type="gene ID" value="Snas_5499"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5499"/>
    <dbReference type="eggNOG" id="COG1611">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058336_0_4_11"/>
    <dbReference type="OMA" id="MFVKYSQ"/>
    <dbReference type="OrthoDB" id="902542at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102682">
        <property type="term" value="F:N6-(Delta2-isopentenyl)-adenosine 5'-monophosphate phosphoribohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00730">
        <property type="entry name" value="TIGR00730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0203">Cytokinin biosynthesis</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="241" mass="26445" checksum="DD8C2C58684C3E6F" modified="2010-04-20" version="1">MMPNANPNPKITSEAHLLDSVHRGEWKQRDAWRALRILSEFVDGFETLSDLEPAVSVFGSARTKPGSEEYVLGEQLGAALAKANFGVITGGGPGIMEAANRGARSAGGVSIGLGIELPFEQKLNDYIDIGLDFRYFFARKTMFVKYSQAFCVLPGGFGTLDELFEALTLVQTKKVTRFPVVLMGVSYWQGLIDWLRDRMLEGGKIAEQDLDLMLLTDDVDEAVSHIVSACAYLKECGDETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW25</accession>
    <name>D3PW25_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5515</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020717.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5515"/>
    <dbReference type="EnsemblBacteria" id="ADD45146">
        <property type="protein sequence ID" value="ADD45146"/>
        <property type="gene ID" value="Snas_5515"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5515"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_0_0_11"/>
    <dbReference type="OMA" id="QIFKHHC"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="106"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="334" mass="36438" checksum="D620A8E5CC1DFEF8" modified="2010-04-20" version="1">MGRYVIRRLLQAVLTFGLVLFLLHYLLSLAIQLNGNPARTFFGNKSPSPEQLAAVEKRFGLDDACLDQLGNPCLTMFGKRLGDWATFDFGTDFQGTEVSSLIAQAIPPTLTLFAISTAVWILFGVTAGVLAALRRGKFFDHLTKLGTVAMIAVPTFLLLVLTQKVVGVWLGNWARDTFGRDSFLAVIFQPSYDPYQPFLSLLVPGLVLGAFGIAGITRLSRTSMLENLRADYVRTAKAKGLKPTRVVIAHTLRNSLIPVVTLVGFTLAEALGGAVITEGVYSIPGMGGLAWRATRENDLPVVIAVVAILSICYMIVTLIIDLMYAVLDPRIRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW55</accession>
    <name>D3PW55_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MMPL domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1508</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016783.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1508"/>
    <dbReference type="EnsemblBacteria" id="ADD41212">
        <property type="protein sequence ID" value="ADD41212"/>
        <property type="gene ID" value="Snas_1508"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1508"/>
    <dbReference type="eggNOG" id="COG2409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005108_4_1_11"/>
    <dbReference type="OMA" id="DRFWWPR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="523"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="547"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="580"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="620"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="647"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="171"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="520"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="704" mass="74290" checksum="A546AC9A774BCF17" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWC0</accession>
    <name>D3PWC0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016848.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1574"/>
    <dbReference type="EnsemblBacteria" id="ADD41277">
        <property type="protein sequence ID" value="ADD41277"/>
        <property type="gene ID" value="Snas_1574"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1574"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_0_1_11"/>
    <dbReference type="OMA" id="YTYVPNK"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="31"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="258" mass="28541" checksum="6E990BF148EA5E9F" modified="2010-04-20" version="1">MNEEEPAQRIARTTELLWGTGQPGKRGPKPRLSLDKIARAAIAIADADGLAAVSMQRVAADLGYTPMSLYTYVPNKELLLEAMLDVVAGSRLPEPREFDDWRTEMHAYVADMWKMFERHPWVLHVQVVGPPTGPGQLRWFERLLSILDKTGLSLPEYPSVGLFLLAAVRGMAKLTLDMRDLHGSAADARAADAASDSMIAKYVDPVNFPLLTSVYSQPPPETEPGWYRPGVVPEDLRYGTDRLLDGIEAQVARSRDTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWK4</accession>
    <name>D3PWK4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3564"/>
    <dbReference type="EnsemblBacteria" id="ADD43226">
        <property type="protein sequence ID" value="ADD43226"/>
        <property type="gene ID" value="Snas_3564"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3564"/>
    <dbReference type="eggNOG" id="COG5285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1011392_0_0_11"/>
    <dbReference type="OMA" id="HGTHANA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="239" mass="26474" checksum="3A77C0DAFB1433A1" modified="2010-04-20" version="1">MASPAGISCERPNNTLVPLRWDDELVNLVLAGHTRIAQAIGAEDLRWISGYVSVKEPHSPPLWWHQDWWAWDHPVSFQREAPQVALLCYLSDTTQTTGALRVLPGSHAASTPLHRILPEAHSDESTGLDLHHPAMVDQPHQVTLELRAGDAVITDYRLLHGTHAHAADHRRDCVILNFAPAWNTLPADIRGHLISHSALPRHDEPVTPTTVTALLPSFDGPRRDLPLNRNAPATFETTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWN9</accession>
    <name>D3PWN9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3601"/>
    <dbReference type="EnsemblBacteria" id="ADD43261">
        <property type="protein sequence ID" value="ADD43261"/>
        <property type="gene ID" value="Snas_3601"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3601"/>
    <dbReference type="HOGENOM" id="CLU_213404_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027575">
        <property type="entry name" value="LD_lanti_pre"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04363">
        <property type="entry name" value="LD_lanti_pre"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="52" mass="5685" checksum="E230AA706DCB683E" modified="2010-04-20" version="1">MTDVNTQQTDMESFEDLFNLDVRVQAGGRSARRCNPTNDGCSNSCTSVGCPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXH1</accession>
    <name>D3PXH1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017005.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1736"/>
    <dbReference type="EnsemblBacteria" id="ADD41434">
        <property type="protein sequence ID" value="ADD41434"/>
        <property type="gene ID" value="Snas_1736"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1736"/>
    <dbReference type="eggNOG" id="COG5500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111152_0_2_11"/>
    <dbReference type="OMA" id="AMQRINV"/>
    <dbReference type="OrthoDB" id="2075110at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="166" mass="17861" checksum="A1C509F88DC55466" modified="2010-04-20" version="1">MRILSTITLLLSTLSAGLMAGLFAGFAYAVMPGLRNSADRTLIEAMQRINVAIINPVFMTAFMGGLLFTVGAVALHWRGDLRPVLPWVIAGCVLFLVMFGVTSAVNVPLNDALARAGDPDKIADLAAVRESFEARWITWNIVRALAATGSFACFCWALIAHGRHTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXL5</accession>
    <name>D3PXL5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type branched-chain amino acid transport systems periplasmic component-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3688</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018916.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3688"/>
    <dbReference type="EnsemblBacteria" id="ADD43345">
        <property type="protein sequence ID" value="ADD43345"/>
        <property type="gene ID" value="Snas_3688"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3688"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_1_2_11"/>
    <dbReference type="OMA" id="MCAPNIF"/>
    <dbReference type="OrthoDB" id="538961at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049542" evidence="1">
        <location>
            <begin position="26"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="35"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="399" mass="43280" checksum="EE2F7812111514DD" modified="2010-04-20" version="1">MSIRLTRRRFLSLTSAGLVATPLAACTSSDPNPDTLKIGWVGPLTGKVKIVGEEMRTAAELYLKLKNDKLGGRKAELVVVDEGDTPKDAMPKVQELIKDDEITALTGILYSPTYLATAELAQERGIPLLGSGGRPEMDPEKLNNLDGLWHTSWINGQTSEALAPYVYKEIGGPVYVIGPDDAGGYGYTKTFAKTYKELGGKLANPGGKPTMTPYPETSDWTVYLDEIHNSKAEAVFVFYGGESAVGFVKQYAASDVKKIPLFTSFITEGSVLQAQGKAALGIKSSVPYATDLDNNANRKLISAWSDAREDLPSTMAVGAWDSMLVLDMAIGRIPDGEEVTREAVKKQIDSLGEIESPRGVWQMGEKTHAPVQRYYLREVRKDGEVISNVALKTLATLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXV8</accession>
    <name>D3PXV8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020858.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5657"/>
    <dbReference type="EnsemblBacteria" id="ADD45287">
        <property type="protein sequence ID" value="ADD45287"/>
        <property type="gene ID" value="Snas_5657"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5657"/>
    <dbReference type="HOGENOM" id="CLU_2275717_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045686">
        <property type="entry name" value="DUF6189"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19688">
        <property type="entry name" value="DUF6189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="102" mass="11259" checksum="635BB7A99C634FF2" modified="2010-04-20" version="1">MDLTDFITTSESVIERLVDKLGDDALMRRYADSIRGNSGAGEWQIAMEDLVALLRQHKIPVTATDLRDLNAVFGYLSQSPSEEVSSRAQTSLDNDVSKLTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY74</accession>
    <name>D3PY74_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5773"/>
    <dbReference type="EnsemblBacteria" id="ADD45403">
        <property type="protein sequence ID" value="ADD45403"/>
        <property type="gene ID" value="Snas_5773"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5773"/>
    <dbReference type="HOGENOM" id="CLU_808690_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="390" mass="41112" checksum="B30B607E8DECF20C" modified="2010-04-20" version="1">MGVKYGPSKDQIKQMAEEVREAAIRVKGEKELRMCPKTGHGSEWAGQLAVDANGAMNTYQPEGKYGDYGIGEDNRYLGTAKDWATLESGYQWIPGEFERYLMPEPHDFDALVDSAQKLTKDFVNVGQAKDPANVPAGTPTSVAPGTSAVDQPIRLSMGFTSDWSGHFADGFQRYLSEIPDVTRRQAVVAETLYEAAVAARDIYGAGREELGNIAKNAKLAIEGVEAGKSTGGCAGSSMATGFALIAAAATVAAGVSTLPISGPAVISGAMAAGNWTIVVGISSAIAAGSPLIPAPEKIELLASDVDGVIEKMKEALTKREKTVTDSEEAFAKKLGANSEMVEKNKVTGKDGGKSQDNAFFPRRPAMLDMSTDLKDLKDPATGFTHPVAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY94</accession>
    <name>D3PY94_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1764</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1764"/>
    <dbReference type="EnsemblBacteria" id="ADD41461">
        <property type="protein sequence ID" value="ADD41461"/>
        <property type="gene ID" value="Snas_1764"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1764"/>
    <dbReference type="eggNOG" id="COG2318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097062_2_1_11"/>
    <dbReference type="OMA" id="VEYGWFC"/>
    <dbReference type="OrthoDB" id="2047691at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007061">
        <property type="entry name" value="DUF664"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04978">
        <property type="entry name" value="DUF664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="145" mass="16010" checksum="13983310ACA9D799" modified="2010-04-20" version="1">MACLNYLRDRVVAKLSGLSDEQASDPGVPSGTSPMGLVKHLTSAELNWFVWAYTAEAEEQWEHSPLPDELDSVDSVIAEYRAANERCDAIIEACTDLGAPGKQIVWEGEPSPCLRWILVHTIEDTARHAGHLDILRERIDGSIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYL9</accession>
    <name>D3PYL9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3796"/>
    <dbReference type="EnsemblBacteria" id="ADD43452">
        <property type="protein sequence ID" value="ADD43452"/>
        <property type="gene ID" value="Snas_3796"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3796"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_34_6_11"/>
    <dbReference type="OMA" id="ASHVGFK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="151" mass="16632" checksum="851C827197BA5530" modified="2010-04-20" version="1">MTKPDIRRATAADLPAIVAMLADDPLGATRETPGDLRPYRTAFAALDADERQHLMVADRDGTVVGVLQLTVIPGLSRTAMTRGLIEGVRIHRDERGGGLGSDLIQWAVDEARRQDCGLVQLTTDITREDAHRFYERLGFAKSHYGYKLSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ01</accession>
    <name>D3PZ01_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021001.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5800"/>
    <dbReference type="EnsemblBacteria" id="ADD45430">
        <property type="protein sequence ID" value="ADD45430"/>
        <property type="gene ID" value="Snas_5800"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5800"/>
    <dbReference type="eggNOG" id="ENOG50341EX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1957138_0_0_11"/>
    <dbReference type="OMA" id="HAFSAWA"/>
    <dbReference type="OrthoDB" id="1767617at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="137" mass="15000" checksum="FB2D5EC423635600" modified="2010-04-20" version="1">MRMNANHRLGAVVTATLVLGSVSILTTGVWCRIDPAGFAEFTNWPEHEHFLHDAGVFQMGIGLMMAAAIWWRDAVAVVLGGFVFTNTFHAYNHYVDMDSGGNPSDWWNLALVSAIVAVGLVFRLRTLRRRAVAAGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ46</accession>
    <name>D3PZ46_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021046.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5846"/>
    <dbReference type="EnsemblBacteria" id="ADD45475">
        <property type="protein sequence ID" value="ADD45475"/>
        <property type="gene ID" value="Snas_5846"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5846"/>
    <dbReference type="eggNOG" id="COG0237">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092760_1_0_11"/>
    <dbReference type="OMA" id="FPFACEC"/>
    <dbReference type="OrthoDB" id="1924129at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="28107" checksum="1B009876A463F3E6" modified="2010-04-20" version="1">MRPLWIGGQAGCGKSTVARILARRHGLRWYNADTRTWAHRDRALRAGDPDARRFEELDPVERWRRPVPELLRMSLHHVRGPMVAEDVRGLPAPLTIAEGTTVTPRVTGDDPAVWLLASRATRVARLAGRGLGEGQLALYLELAEVVAAEVRAAGAPVITVDDRDVAATVAAVEELFAEPLAAGPKAEGPQERRALLREANAAIIEQCRGFSSRPWANVELSQIRRGFGCECGDPGCLAEVELAVCDYAPPVLAPGHTPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZF6</accession>
    <name>D3PZF6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1934</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017201.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1934"/>
    <dbReference type="EnsemblBacteria" id="ADD41630">
        <property type="protein sequence ID" value="ADD41630"/>
        <property type="gene ID" value="Snas_1934"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1934"/>
    <dbReference type="eggNOG" id="ENOG50331TA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137406_0_0_11"/>
    <dbReference type="OMA" id="AFGRNGF"/>
    <dbReference type="OrthoDB" id="1932924at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="130" mass="14563" checksum="79A109634768D5C2" modified="2010-04-20" version="1">MTTVAFVDESTAGKQSDAWHLEIFEETLSLRELIRRRVFQEVAEHNAKNTPVFNGLVQPEDAEVTLNGYRLRKARTIDAGKQFDKAVEAFDRNGYVVLVDDRQVEELDAVIDIAQGTTVTFLKLVPLVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZG2</accession>
    <name>D3PZG2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017207.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1940"/>
    <dbReference type="EnsemblBacteria" id="ADD41636">
        <property type="protein sequence ID" value="ADD41636"/>
        <property type="gene ID" value="Snas_1940"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1940"/>
    <dbReference type="eggNOG" id="ENOG50313CI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064499_0_0_11"/>
    <dbReference type="OMA" id="FTHIMQM"/>
    <dbReference type="OrthoDB" id="1039062at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048725" evidence="2">
        <location>
            <begin position="31"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="266" mass="29627" checksum="915DCD08FBF733A8" modified="2010-04-20" version="1">MSASISRRSLLAATGVTVAAAGLAYTTAEASTVGKAEWQERWAPDPGSDGLDAFEGVEDDRADSHPDGQPHIYVEDDAYRFNMHMEDVDSHTDRQRQEVKGMRTPAGGDFLVIEPGSTWRLNYQVFIPETLLATKTFTHITQLYSPKIGPAMMISLRRVDGVETMELKDHPQDILVERTELAPLKERWIDIELEILAGDAPDGAVRWVVKDGSQTIVDVSKDGLGTSLEGVRIRPKWGIYRSLEDDTGSLRDCHLLMRGMRAYEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZI8</accession>
    <name>D3PZI8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1966</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1966"/>
    <dbReference type="EnsemblBacteria" id="ADD41662">
        <property type="protein sequence ID" value="ADD41662"/>
        <property type="gene ID" value="Snas_1966"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1966"/>
    <dbReference type="eggNOG" id="COG5395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078522_1_0_11"/>
    <dbReference type="OMA" id="WWIERTR"/>
    <dbReference type="OrthoDB" id="1436862at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018750">
        <property type="entry name" value="DUF2306_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10067">
        <property type="entry name" value="DUF2306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="237" mass="26634" checksum="30F0350908686DF0" modified="2010-04-20" version="1">MIPLWVVCGAFFAWRTPAYLGFTPEASFVALRDNTHYLMLSAHVVLGTVTLTCCCLQLWPWLRQHHPKVHRISGRIYVTAVIPASVLAFVSAVWQDLPVPGRISNMTLSILWLLMTIAGFRMARARRFAEHRRWMIRSFALCISIIANRVWTGIMVVALMPFTDSVYGGDWDAMFMDAALAAVWLSWIVNLLIAEWWIERTRRPRPKPPTGPVTGDGTRPAAVAGHRDTPPVPLSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZJ3</accession>
    <name>D3PZJ3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017238.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1971"/>
    <dbReference type="EnsemblBacteria" id="ADD41667">
        <property type="protein sequence ID" value="ADD41667"/>
        <property type="gene ID" value="Snas_1971"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1971"/>
    <dbReference type="HOGENOM" id="CLU_1460436_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="19806" checksum="1479A24EE5160B33" modified="2010-04-20" version="1">MNEGPAQTVTPIERMYRAGKELIPGVATKVSGAAQSLQLACPAIDVQTALAGDPKGMRSILELCEELHDALGRLTVSLNNCASAVVTAADDFVATDERAARDVRSVDAELRSAVPTPAVEVSEIDDHSAPGATVETVPSDESPSKTHEKHIDSTPAPEDLPTAEENQRERDERIDDVELPEGEWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZJ9</accession>
    <name>D3PZJ9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017244.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1977"/>
    <dbReference type="EnsemblBacteria" id="ADD41673">
        <property type="protein sequence ID" value="ADD41673"/>
        <property type="gene ID" value="Snas_1977"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1977"/>
    <dbReference type="eggNOG" id="ENOG5033PJY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079354_0_0_11"/>
    <dbReference type="OrthoDB" id="931964at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="308" mass="34468" checksum="AC3448CF2FFF72B1" modified="2010-04-20" version="1">MVSPPQASGDKMPIRVRPQSGPEVLCPSAADLTAMIRRIGGEGDHFLVLERVPYAPREFIQVYRDEDNPFNVEYRDGGAQQYDTEISDPEDVALVFSVWARREPEWKSGVDWRPSYLHPDVEVTPLSEAAARSATERARRYLDEGFLSFEAMAQEISDCAERDEPVTIEQAEILLEPLWIERVEQQRSWPDVTDVDRIAAAFAQLDDSGVTARMHFSCCMNCGTGEIAAERAAGDHGYVFFHYQDTENAVGGELYLAYGSHAGDDVEGEAVGQEVVKALQAAGLSTEWDGSIRQRIRVVGLDWKKRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q005</accession>
    <name>D3Q005_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5906</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021105.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5906"/>
    <dbReference type="EnsemblBacteria" id="ADD45534">
        <property type="protein sequence ID" value="ADD45534"/>
        <property type="gene ID" value="Snas_5906"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5906"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060016_2_0_11"/>
    <dbReference type="OMA" id="MMASTYG"/>
    <dbReference type="OrthoDB" id="1503557at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="5"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="150"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="287" mass="30342" checksum="4FA6B1D993A6FBCF" modified="2010-04-20" version="1">MDPLALLLVGAAAVCHALWNLAAKRASDGGPVFVWLNTVASAVIYLPLVAVLVVIQPPRWNWTLLVAILVTGILHSGYSVILQRGYQHGDLSVVYPLARGTGPALSVGFAIVFLGERPGLIGFLGALGVVAGILVIGLGKAGKGTKLTAGIGYGLLTGVFIASYTVWDAWAVGPLAISPILYDWGNNIVRGTILTPYALRRRAEIRRVWTQHRSSVFIVATIAPAAYILVLFAYRFAPVSLVAPARELSIVIGSVFAWLLLREPQAGRRIAGAVVVLLGVAALAVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q079</accession>
    <name>D3Q079_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021179.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5982"/>
    <dbReference type="EnsemblBacteria" id="ADD45608">
        <property type="protein sequence ID" value="ADD45608"/>
        <property type="gene ID" value="Snas_5982"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5982"/>
    <dbReference type="HOGENOM" id="CLU_161187_1_0_11"/>
    <dbReference type="OMA" id="WDEYADE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021426">
        <property type="entry name" value="DUF3073"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11273">
        <property type="entry name" value="DUF3073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="71" mass="8200" checksum="A49C76A1EA040C78" modified="2010-04-20" version="1">MGRGRAKAKQAKVARQLKYHTPDTDLGALERELSGNDARDDDYDDPYDAYKPRSGTDEPEPREEDWLPRKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q092</accession>
    <name>D3Q092_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5995</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021192.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5995"/>
    <dbReference type="EnsemblBacteria" id="ADD45621">
        <property type="protein sequence ID" value="ADD45621"/>
        <property type="gene ID" value="Snas_5995"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5995"/>
    <dbReference type="eggNOG" id="COG4270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126433_7_0_11"/>
    <dbReference type="OMA" id="LWTLQIV"/>
    <dbReference type="OrthoDB" id="2018019at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13564">
        <property type="entry name" value="DoxX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="147" mass="15727" checksum="38834D38E2934BBD" modified="2010-04-20" version="1">MSDNATPAQDTKRPGKALNIILWVLQGLLAAFFVFASAPKLLGDPTAVEMFGKIDFGDWFRYLTGIVELAGAIGLVIPRLSSLAASGLAIVMVCATVANLTALEMAWAAPQTIVLAALFVFIAWGRRDQNKRLLAMFKGSKTEPSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0N5</accession>
    <name>D3Q0N5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2077</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2077"/>
    <dbReference type="EnsemblBacteria" id="ADD41771">
        <property type="protein sequence ID" value="ADD41771"/>
        <property type="gene ID" value="Snas_2077"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2077"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="QPDWVAY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00740">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51178">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="11"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="7">
        <location>
            <begin position="426"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="296"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="382"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="400"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="505" mass="53405" checksum="7E32302F38AEFFF6" modified="2010-04-20" version="1">MRQGQRLNDRYRLDERVAAGGMGEVWKGYDERLNRIVAVKVLHHALASDVVFQHRFHIEARAIAALQHPGVVNIYDFGDETGEDGQIVYLVMEYVDGKSLQQILQEGGKLDVDETMRVIAGTAEALQVAHRAQIIHRDIKPGNILISKNGAPRIVDFGIARTAGAAGLTNTGMVMGTAAYVAPEQLRGDDPTPAADIYSLGVVAYQCLSGRKPFDSDVPATIIATALSDEPPPLPEEIPETVAAIVLRALAKEPDGRWASAADFAAACRKPDNAPVSPAPAGDAATMVTPASAAEAPTVVTPPPPGDAASQDADSVTPPSMRGSAPPQHPGQNDGPLTPVPQPKPRRNGLLIGIIVILVLLLLGVGGYVVYLRPWVQTNVAQPGGEETSAVEEATSEESPSESESSSSPEPTTSSAEPTSESESPEPETAEIPPVDGLSEEEAIQVLNGEGFENIVTEYDGDGAKVCSVDSQAPEPYQEAELTTEITIYVQYVDDLTDCRYAGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0N8</accession>
    <name>D3Q0N8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017345.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2080"/>
    <dbReference type="EnsemblBacteria" id="ADD41774">
        <property type="protein sequence ID" value="ADD41774"/>
        <property type="gene ID" value="Snas_2080"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2080"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060397_2_0_11"/>
    <dbReference type="OMA" id="GAMHWSG"/>
    <dbReference type="OrthoDB" id="1865374at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="50"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="211" mass="23460" checksum="E70B984C068977D6" modified="2010-04-20" version="1">MVEDRDIKELVRRGYNAVPYHHDAEGSGAWQQTRMTRKLLERLAPASRLLDLGCGSGLPLARDATVAGHRVTGVDISEVAIARATELVPEATFIRADAGTATFEPESFEAIACLYMIFHLEPEEQRRLLATVREWLVPGGLLLVIAGNTPSVGITENWRDSGTSMWWSHPGAETYREWVKEAGFTLVEDEFIPEGSKGHRAYWCRRPAPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0R5</accession>
    <name>D3Q0R5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017372.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2107"/>
    <dbReference type="EnsemblBacteria" id="ADD41801">
        <property type="protein sequence ID" value="ADD41801"/>
        <property type="gene ID" value="Snas_2107"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2107"/>
    <dbReference type="eggNOG" id="COG2911">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023173_0_0_11"/>
    <dbReference type="OMA" id="WYGRLWG"/>
    <dbReference type="OrthoDB" id="1262147at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="574"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="603" mass="66185" checksum="8334A47B57C9C26E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Y4</accession>
    <name>D3Q0Y4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4082</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019305.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4082"/>
    <dbReference type="EnsemblBacteria" id="ADD43734">
        <property type="protein sequence ID" value="ADD43734"/>
        <property type="gene ID" value="Snas_4082"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4082"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_28_0_11"/>
    <dbReference type="OMA" id="PANDHIR"/>
    <dbReference type="OrthoDB" id="1204683at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16925">
        <property type="entry name" value="TetR_C_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="193" mass="21150" checksum="3CB7058A6D6B3C53" modified="2010-04-20" version="1">MGRAKQFDPDVVVDKAMRVFWRDGYAGTTPQRLVDELGIGRGSLYNAFGSKAGLYERALRRYYETETVRLIEILDGAGSPRVRVRAALDLVVTAALADTERRGCMAANAAVEFGQTDATVNHLVRRVFERQEAAFRGAIEEGQRAGEFTTDADASDLAYVLLTTINGIRVLAKANPDEKRLRGLAATALRALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Y7</accession>
    <name>D3Q0Y7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenosine deaminase</fullName>
            <ecNumber evidence="4">3.5.4.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4085</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.4" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019308.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4085"/>
    <dbReference type="EnsemblBacteria" id="ADD43737">
        <property type="protein sequence ID" value="ADD43737"/>
        <property type="gene ID" value="Snas_4085"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4085"/>
    <dbReference type="eggNOG" id="COG1816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039228_7_1_11"/>
    <dbReference type="OMA" id="RGWFRFQ"/>
    <dbReference type="OrthoDB" id="554648at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114">
        <property type="entry name" value="PTHR43114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A_deaminase" evidence="3">
        <location>
            <begin position="9"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="330" mass="34768" checksum="7CD5AC558C1B4168" modified="2010-04-20" version="1">MTRELHGLPKAHLHLHVAGAMRETTLWELSQRHRLPPAPPPLGNARRTWAQFQVRYDAARDAIRTTDDLARVIVEAAADDAADGCGWLEIQLDPTAYAPILGGLRATLEAALSGAANASIPVGVIVASSWARSGEHALQLAELAVEYADAGVVGFGLSNDERRGSPADFVPAFEIAAEAGLARTPHAGFYLGAEHVRDCVELLGATRIGHGTAAATDAGTMALLAERGIALEVCPTSYPPFGVHELAEIPVASLLAAGVLVTIASDDPLLFGTGLAGQYAICRDILGLSDDVLAQLAEHSVEHSMAPQPIKTAMLAGIDEWRKPTARLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0Z1</accession>
    <name>D3Q0Z1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019312.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4089"/>
    <dbReference type="EnsemblBacteria" id="ADD43741">
        <property type="protein sequence ID" value="ADD43741"/>
        <property type="gene ID" value="Snas_4089"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4089"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055817_1_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043917">
        <property type="entry name" value="DUF5753"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19054">
        <property type="entry name" value="DUF5753"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="17"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="276" mass="30834" checksum="A4427BEB41284329" modified="2010-04-20" version="1">MSDHSPTVAHGAFLKMLRELRLAARYDYSDAAAELGVNAKTIKRWEEGANIPSRSSIKVLGEFYGASPAQIEMMCSLARDAKRSGLVEKFKGGAPPEFQSFAEHEASAISILTYQPEFIPGLAQTPDYLREIHKRYLDFLIPNPRAIHAFRQNRQRRVFSRRHLPEIKMVIGVAAMIYLDALPATVRNGQIDRLLELSAKPTIDIKVVTVPHTAMGGGFTIMTPDEKSHGASAFAYLESQDAGRYVEDRDTLSVYDKIFSSVFNLAVLLEEYLDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q120</accession>
    <name>D3Q120_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Cytochrome bc1 complex cytochrome c subunit</fullName>
            <ecNumber evidence="3 10">7.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Snas_4119</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">Binds 2 heme groups covalently per subunit.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="3 10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019341.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4119"/>
    <dbReference type="EnsemblBacteria" id="ADD43770">
        <property type="protein sequence ID" value="ADD43770"/>
        <property type="gene ID" value="Snas_4119"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4119"/>
    <dbReference type="eggNOG" id="COG2010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086567_0_0_11"/>
    <dbReference type="OMA" id="LFRTNCA"/>
    <dbReference type="OrthoDB" id="1469969at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:ubiquinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009152">
        <property type="entry name" value="bc1_cytC-su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000007">
        <property type="entry name" value="Ubiq_cycred_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 10 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="13">
        <location>
            <begin position="50"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="13">
        <location>
            <begin position="151"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000007-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000007-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD43770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="271" mass="28576" checksum="F887E30F62C49937" modified="2010-04-20" version="1">MAAPTRHRHRWRRRLGALARFIGALALVGGIYTGFAPGIYADEPDKEFEKLAAEGKELYDNSCVSCHGPKAEGVDGRGPSLIGVGGAAVEFQVNSGRMPMARQEAQAERKQPMFTPKEAEALAAYIQQLGGGPEGVTDEEIDALTGDLSDTEIAEGGELFRVNCGSCHGFATGGGALSSGKYAPALEGVASDEIYEAMLTGPQNMPVFANAQLTPEEKVEVIAYIEYLNEDRDPGGPLTLGRFGPSTEGLAIFLVGITTLAVATLWIAGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q122</accession>
    <name>D3Q122_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019343.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4121"/>
    <dbReference type="EnsemblBacteria" id="ADD43772">
        <property type="protein sequence ID" value="ADD43772"/>
        <property type="gene ID" value="Snas_4121"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4121"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127113_0_0_11"/>
    <dbReference type="OMA" id="AWLASWS"/>
    <dbReference type="OrthoDB" id="1950078at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="131" mass="14498" checksum="E5E9CE3CE37B4387" modified="2010-04-20" version="1">MTTYSVILYSHNPKVRHGMRSAIGEQPTEDVTIEYLEASDYDEAIRLIDTYEIDLMLLDGESQPAGGLGIARQLRDELDDPPTTCVVLKRAADQWLAAWSRADASLTHPLDPIRTSAAIVELLRSRATATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q214</accession>
    <name>D3Q214_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribonuclease HII</fullName>
            <shortName evidence="11">RNase HII</shortName>
            <ecNumber evidence="11">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rnhB</name>
        <name evidence="14" type="ordered locus">Snas_2189</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 11 12">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11 12">Belongs to the RNase HII family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="11"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017452.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2189"/>
    <dbReference type="EnsemblBacteria" id="ADD41881">
        <property type="protein sequence ID" value="ADD41881"/>
        <property type="gene ID" value="Snas_2189"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2189"/>
    <dbReference type="eggNOG" id="COG0164">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036532_1_0_11"/>
    <dbReference type="OMA" id="YPTKLHL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07182">
        <property type="entry name" value="RNase_HII_bacteria_HII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00052_B">
        <property type="entry name" value="RNase_HII_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022898">
        <property type="entry name" value="RNase_HII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF18">
        <property type="entry name" value="PTHR10954:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_HII" evidence="13">
        <location>
            <begin position="17"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD41881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="211" mass="22034" checksum="2D5E86BC5959CF1F" modified="2010-04-20" version="1">MYVLENALRRRGFTLVAGADEAGRGACAGPLVVAAAILPDGARGQIAGLTDSKLLTERAREDIYAQVVDRAVAHAIVVISPAEVDRLGVGASNLSGMRRALARLDPMPAYALTDGFPVPGLPVPGLGVWKGDRVAACVAAASVLAKVTRDRIMTELEQNHPGYGFAEHKGYGTAAHTHALRTLGPCPQHRLSYANVVEAVSGNPRVAQAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2F5</accession>
    <name>D3Q2F5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019459.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4239"/>
    <dbReference type="EnsemblBacteria" id="ADD43888">
        <property type="protein sequence ID" value="ADD43888"/>
        <property type="gene ID" value="Snas_4239"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4239"/>
    <dbReference type="eggNOG" id="ENOG5033FMT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2452872_0_0_11"/>
    <dbReference type="OMA" id="LETRWPW"/>
    <dbReference type="OrthoDB" id="2095320at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="88" mass="9266" checksum="6480E5A3EAE6BFDC" modified="2010-04-20" version="1">MSDYLASLIRTGIPAGVGAVLAWAASKGFDIPEAARTEIIAALTAAATTIYYAVVRAAENTWPVVGRLLGTSRQPEYSAPLKLDSDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2M4</accession>
    <name>D3Q2M4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_6152</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021346.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6152"/>
    <dbReference type="EnsemblBacteria" id="ADD45775">
        <property type="protein sequence ID" value="ADD45775"/>
        <property type="gene ID" value="Snas_6152"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6152"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="LDPINTI"/>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="334" mass="36039" checksum="22B26646F362614D" modified="2010-04-20" version="1">MALLKVDDLSVRFEQRGKPDVRAVDGLSFTVDSGEVVGLVGESGCGKSVTSLALMGLLHSRNARVGGTAEFDGVDLLKLRPNEMRDLRGSDIAMIFQDPLSSLNPVVPIGVQVTEILTRHRGMKGEPARKEAADLLDRVGIPDPNRRLKEYPHQLSGGMRQRALIAMAVACAPRLLIADEPTTALDVTIQAQILELLKDLVVSQGTALLMITHDLGVVAGLCDDINVLYAGKVVEAAARRPLFAAPTHPYSVGLLGSIPRLDAPRGEPLSPIRGSVNDNIAWKDGCAFAPRCDHYTMECLQGTIEMSQTYTGHRFRCVNPVENHEVQPGTEPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2M9</accession>
    <name>D3Q2M9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021351.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6157"/>
    <dbReference type="EnsemblBacteria" id="ADD45780">
        <property type="protein sequence ID" value="ADD45780"/>
        <property type="gene ID" value="Snas_6157"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6157"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081534_2_0_11"/>
    <dbReference type="OMA" id="QTHYFWP"/>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="51"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="21907" checksum="29B45DB20F3253C2" modified="2010-04-20" version="1">MDDATKLRWLSRLFFSGPMGRMSASAMEKRNSDAEAEAVATLDPSPSESVLAIGFGPGVGIRLLAERLPEGQIGGIDPSAYMVKRATRRNRAAAARIRLERAYTAAIPWPDASFDGAIAVNSIQFWNPLADNASEVARVLRPGARLVTFTHDWALARGGQTLEGWQTTAEATFRDCGFTDVESHPGKSEDGHIVAFCATRSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2R6</accession>
    <name>D3Q2R6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021388.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6194"/>
    <dbReference type="EnsemblBacteria" id="ADD45817">
        <property type="protein sequence ID" value="ADD45817"/>
        <property type="gene ID" value="Snas_6194"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6194"/>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058424_0_0_11"/>
    <dbReference type="OMA" id="VGNNWDG"/>
    <dbReference type="OrthoDB" id="302683at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="SSF50974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048591" evidence="1">
        <location>
            <begin position="33"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="414" mass="45620" checksum="D273175182324F1C" modified="2010-04-20" version="1">MSRASARTLVTALAAVIVLSAPAVLVADTATADEHQTRPVLFVGNNWDGTIDVVSDDENLDPVGQINAVPDIAERKAEIRRDPVALAYYLAIRQFIGEGHDQYVDDMYTTPDAKLLIVSRPSLADVVAIELGTGDIAWRFPVEGYRSDHMALSPDGTQVAVSASTGNTVHLLDVYTGQEEDSFATGDSPHENVYTNDGQYVVNASIGNVYTPFDHPLLGPTKGKRYFQIYDRYTGQLVKRVNMADKLADAGYRDMSASVRPMTFSPDERFVYFQVSFEHGFFEYDLRTDTVTRRAELPIADEVEDMPREEYLLDSAHHGIAMNTDGDRICVAGTMSDYATVVDRETFQHQGLIESGEKPYWATRSGDGQRCYVSWSGSDRISAISYTTGQETASAAVGDHPQRMRVGVVAADWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2W8</accession>
    <name>D3Q2W8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021440.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6249"/>
    <dbReference type="EnsemblBacteria" id="ADD45869">
        <property type="protein sequence ID" value="ADD45869"/>
        <property type="gene ID" value="Snas_6249"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6249"/>
    <dbReference type="HOGENOM" id="CLU_1915808_0_0_11"/>
    <dbReference type="OrthoDB" id="1465613at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="134" mass="14587" checksum="9D1ED35F3E49C611" modified="2010-04-20" version="1">MSNVVDPNNLSGDELVAALRRCANRPNQQAAIQLLVSHGHLLDRADVRREFVMAEEHDGVVYAWMHWAPIEDTRLPVPLSSGEAALLRIAASIGDFGIDVNLANTITSLDTPNTRRVLAAIAHAAGKDRLVSWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2X5</accession>
    <name>D3Q2X5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021447.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6256"/>
    <dbReference type="EnsemblBacteria" id="ADD45876">
        <property type="protein sequence ID" value="ADD45876"/>
        <property type="gene ID" value="Snas_6256"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6256"/>
    <dbReference type="HOGENOM" id="CLU_1969196_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="127" mass="13521" checksum="2630E6F348CAEC1A" modified="2010-04-20" version="1">MGNSILAGVSLLVFGVLYWQNLWKKLQCWLLVLVGWGLGGLLGDWLQYLIGQANGLTAEWMQVLFGIGVPAAVAVVALLIFVLDMLPDSKVRTKPVGWHTRIAALLVPLSLASMPALGANLSAAIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q460</accession>
    <name>D3Q460_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6327</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021516.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6327"/>
    <dbReference type="EnsemblBacteria" id="ADD45945">
        <property type="protein sequence ID" value="ADD45945"/>
        <property type="gene ID" value="Snas_6327"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6327"/>
    <dbReference type="eggNOG" id="COG1120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_11"/>
    <dbReference type="OMA" id="GEYADRM"/>
    <dbReference type="OrthoDB" id="1752365at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="22"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="54"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="283" mass="30207" checksum="D4279370F7AB83C5" modified="2010-04-20" version="1">MTLASPPPSPASSHGEAVVTALSAEDVTVRLGGALIVDEVSFTVEPGEWLTVIGPNGAGKSTLLHAVAGLLAFDGRVRLYGDDLAALPRRELARRIAVVVQSPVVPEGMTVLDYVLLGRTPHIHALGRESQHDVDVALRVCERLDLMPFTTRALATLSGGERQRAILARALAQLAGTRQALLLLDEPTSALDIGHQQEVLELVDTLRAEEGLTVVSTMHELSIAGEYADRLLLLAAGRLAALGPAAEVLTTELLATHYRARVRVIDSESGPVVVPLRPDRQEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q481</accession>
    <name>D3Q481_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Allophanate hydrolase subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6350</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021537.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6350"/>
    <dbReference type="EnsemblBacteria" id="ADD45966">
        <property type="protein sequence ID" value="ADD45966"/>
        <property type="gene ID" value="Snas_6350"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6350"/>
    <dbReference type="eggNOG" id="COG2049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020207_0_1_11"/>
    <dbReference type="OMA" id="MPWMLAA"/>
    <dbReference type="OrthoDB" id="1848526at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003833">
        <property type="entry name" value="CT_C_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010016">
        <property type="entry name" value="KipI_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34698">
        <property type="entry name" value="PTHR34698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02682">
        <property type="entry name" value="CT_C_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00796">
        <property type="entry name" value="AHS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AHS1" evidence="4">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="204" mass="22253" checksum="04D842D5FC0A11EC" modified="2010-04-20" version="1">MRFLRCGEHALLVELDGLDEVLGRYHALRRHPPVGVGELVPASRTLLVHFDPLLTDREKVARAVEDVPPESPARADDRLVEIPVRYDGEDLEEVSVLTGLSASEVVKSHTGGEYLAAFGGFAPGFLYITGLPETLRLPRRDTPRTRVPSGAVALGGGYTAVYPRDSPGGWHIIGHTCLSMWDLDREPPAALSPGDRVRFVEVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4A6</accession>
    <name>D3Q4A6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_6375</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021562.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6375"/>
    <dbReference type="EnsemblBacteria" id="ADD45991">
        <property type="protein sequence ID" value="ADD45991"/>
        <property type="gene ID" value="Snas_6375"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6375"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_2_0_11"/>
    <dbReference type="OMA" id="RRNFRHT"/>
    <dbReference type="OrthoDB" id="1891092at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="9">
        <location>
            <begin position="6"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD45991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="247" mass="26381" checksum="3BD67200EE0FF617" modified="2010-04-20" version="1">MKSHSMVMLRRNFKHIARNPVSVFNSILMPIFMLLMFVYMFGEAFSVGVDYVDYATPGLMLMAVCYGLGATATAVNSDMTKGIINRFKVMDVSRGAVLNGHVITSVLTNVIAIAALVGVAFAMGFSPAADLLDWLALAGIVILLGFAAGWLTIALGIAAKSPETAGMAAVPMVLLPFFSSAIVPADMMGPGLREFAKYQPFTPIIETMRGLLAGKPETGDTLTAVAWCLGIALVGYLWARSTFKKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4B4</accession>
    <name>D3Q4B4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ThiamineS protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0356</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015645.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0356"/>
    <dbReference type="EnsemblBacteria" id="ADD40074">
        <property type="protein sequence ID" value="ADD40074"/>
        <property type="gene ID" value="Snas_0356"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0356"/>
    <dbReference type="eggNOG" id="COG1977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114601_2_2_11"/>
    <dbReference type="OMA" id="KVTVRYW"/>
    <dbReference type="OrthoDB" id="1995573at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="79" mass="7985" checksum="5172F861170ED274" modified="2010-04-20" version="1">MVTVRFFAGARAAAGVAEARVSATTVAELKAVLVKEYGAELARVLPACGLLVDGVSNHEDLSTLTDGATVDVLPPFAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4C8</accession>
    <name>D3Q4C8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40088">
        <property type="protein sequence ID" value="ADD40088"/>
        <property type="gene ID" value="Snas_0371"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0371"/>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1554338_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="172" mass="19022" checksum="8CEA8D07DD14851A" modified="2010-04-20" version="1">MTGEEYLHSYDPDNSVPGSLSYFTHRFAAMAKRSGFHCTPQKVRHFSATKLLAAKIALPAVAGRLGHSSGGRTTLQYYAAWLRETDDSAVRVLAACMPELPQVRREKSRRDFSAEQPTRTKDELEARICNIRREEGLGPVKIQARLAAEGTDIASSAVWLVLKRHGLNKAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4E4</accession>
    <name>D3Q4E4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0387</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015675.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0387"/>
    <dbReference type="EnsemblBacteria" id="ADD40104">
        <property type="protein sequence ID" value="ADD40104"/>
        <property type="gene ID" value="Snas_0387"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0387"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_3_3_11"/>
    <dbReference type="OMA" id="KMGWDCM"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="21367" checksum="29F3029BF416AB97" modified="2010-04-20" version="1">MSIEFLLTTLVVVATPGTGVVYTLAAGLSRGAKASLIAAVGCTLGIVPHMIAAVTGLAALLHASATAFEIIKYAGVAYLLYMAWATIRDKGALTVEADTAPQSTLRVIGSGVLVNILNPKLTIFFFAFLPQFVPAGAPNALPRMLGLSAVFMLATLAVFALYGVFAAAVREHVISRVRVMTWLRRTFAASFVVLAGRLALTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q547</accession>
    <name>D3Q547_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock protein Hsp20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4451</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019667.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4451"/>
    <dbReference type="EnsemblBacteria" id="ADD44096">
        <property type="protein sequence ID" value="ADD44096"/>
        <property type="gene ID" value="Snas_4451"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4451"/>
    <dbReference type="eggNOG" id="COG0071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046737_12_1_11"/>
    <dbReference type="OMA" id="FEITAEL"/>
    <dbReference type="OrthoDB" id="1523369at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="29"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="155" mass="16992" checksum="0F84886D553E5F14" modified="2010-04-20" version="1">MLVRYRQPWFLSSRVNNEFDRLIAETFGRVEPVFTPPADVSTQGNDVVIALDVPGVAPEDVDVTLEGRFLKITGTRASAQVAEGDRYLARGRFEGSFARTYRVPEGTTPEQVSATVDNGQLIVRVADVTKPEPQPQKIAVTRAAESQALESGETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5Q3</accession>
    <name>D3Q5Q3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0487</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015773.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0487"/>
    <dbReference type="EnsemblBacteria" id="ADD40202">
        <property type="protein sequence ID" value="ADD40202"/>
        <property type="gene ID" value="Snas_0487"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0487"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037105_0_0_11"/>
    <dbReference type="OMA" id="VRCNAVD"/>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="253"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="379" mass="40315" checksum="462F4FFC7148C7D4" modified="2010-04-20" version="1">MDTPAENEESASTVRRWTRKRLWWTIVAATTALLCCGGTTFYVVFLTVSNNSDTGAANYAGCGNGTEISISGDMPKINDLNEEQVGNAAIIIQTGQKRNMSPRAWVIAVATAMQESTLHNYGHLGDRNDHDSLGLFQQRPSKGWGTPDQVTDPEYASTSFYKRLKKVEGWESMDLTAAAQAVQRSAFPDAYAKWEPLATDVVNVLTEGGARTAADGGKSGECAEGAEIAASGWTAPVKDGIVSGFRTPQRPDHYGVDLGSKRGTEIRAAASGVVTTSECNASTNNCDVDGSPSVLGCGWYVDIEHANGIITRYCHMVEQPKVDVGQRVKAGEVIGISGSSGNSSGPHLHFEVHEGGDASNNGAIDPVAWMKQQGINIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5Q9</accession>
    <name>D3Q5Q9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 17">Aspartokinase</fullName>
            <ecNumber evidence="7 17">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ordered locus">Snas_0493</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 18">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 18">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 18">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 17">Belongs to the aspartokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="7 17"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015779.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0493"/>
    <dbReference type="EnsemblBacteria" id="ADD40208">
        <property type="protein sequence ID" value="ADD40208"/>
        <property type="gene ID" value="Snas_0493"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0493"/>
    <dbReference type="eggNOG" id="COG0527">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009116_3_2_11"/>
    <dbReference type="OMA" id="DMIVQTI"/>
    <dbReference type="OrthoDB" id="1067792at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:aspartate kinase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="F:ATP binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:diaminopimelate biosynthetic process"/>
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        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
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        <property type="project" value="UniProtKB-UniPathway"/>
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        <property type="term" value="P:phosphorylation"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:threonine biosynthetic process"/>
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        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="AceGlu_kinase-like_sf"/>
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        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
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        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
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        <property type="entry name" value="Asp_kinase"/>
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        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
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        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Asp_kin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00656">
        <property type="entry name" value="asp_kin_monofn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 18" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="12 17 20" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="19">
        <location>
            <begin position="267"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="19">
        <location>
            <begin position="349"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="7"/>
            <end position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>substrate</name>
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    <feature type="binding site" evidence="16">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
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    <feature type="binding site" evidence="16">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00000709"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00002843"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00004986"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00013059"/>
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    </evidence>
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        </source>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ADD40208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="421" mass="44614" checksum="90D0947B82564FD7" modified="2010-04-20" version="1">MALVVHKYGGSSVENAERIKRVAERIVSARKRGDDVVVVVSAMGDTTDELLDLAAQVSPLPHPRELDMLLTAGERMSMALLAMAINNLGFEARSFTGSQAGMITTSVHGKARIIDVTPGRIRGALDEGAVAIVAGFQGIAQDTKDITTLGRGGSDTTAVALAAALHADRCDIYSDVDGMFTADPRIVPNAKLIDQITYEETLELAASGAKILHLRAVEYARRFNLPLRVRSSYSNKPGTLVTGSMEDLPVEQALITGVAHDRSEAKITVLSVPDEPGQAAELFEVVADAEINIDMIVQNISTKDSGRTDISFTLPKDDGPTAMAALQKARDKIGFAGLLYDDHIGKVSLVGAGMRSHPGVTATFCKALSQAGVNIEIISTSEIRISVVCRDTELDTAVSAVHEAFELGGSEEAVVYAGTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q639</accession>
    <name>D3Q639_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2533</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42214">
        <property type="protein sequence ID" value="ADD42214"/>
        <property type="gene ID" value="Snas_2533"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2533"/>
    <dbReference type="HOGENOM" id="CLU_1414405_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="132"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="192" mass="20589" checksum="A889E9EC2D567333" modified="2010-04-20" version="1">MYDYGPGQPQDPNAYPQQPPQPQQQPPPPVQPTQPYDPSPPMTSGPPAQPTAPQFTGGTAVPAYPTAPVTGAGPLGTTQFPAPGLLPPPPKKRSAAVPILAAVSALLLIGAVVFMILYFNTRSDLADARSTISDNEDSIDKKDDEIKDLEDEKQDADECVKLVEEMFTELSSTPDTTELDRILQEMESTCQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6T6</accession>
    <name>D3Q6T6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0621</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0621"/>
    <dbReference type="EnsemblBacteria" id="ADD40335">
        <property type="protein sequence ID" value="ADD40335"/>
        <property type="gene ID" value="Snas_0621"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0621"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_8_0_11"/>
    <dbReference type="OMA" id="TDITMTI"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="95"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="32017" checksum="0F784B338721117E" modified="2010-04-20" version="1">MTAVGTTTPPEAAAPLRTRTVVWRGLTRSPSGFVGGVIVLLVMGFAFLGPLLIDTTNPSNSDLIWTGPSSEHILGTDGQGKDSFLTLVAGGAEPLWVGILAASIAVVVATVLGSIAGFVRGKLDTFFLQLTDITMTIPSIVLMLVLTAMFRSITPTAIAVIIGLTTWAPLMRSVRAQVLSLRQREFVEAARLQNIPVRTVIFAEVLPNMAGYIFVNFILAINNAIYALVGMYLLGLLPSTADNWGLMIQESWKSGAFKLPEAIPYIAAPLALIILFQIGLITMGRSLEQALNPRLRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Z1</accession>
    <name>D3Q6Z1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015961.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0677"/>
    <dbReference type="EnsemblBacteria" id="ADD40390">
        <property type="protein sequence ID" value="ADD40390"/>
        <property type="gene ID" value="Snas_0677"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0677"/>
    <dbReference type="eggNOG" id="ENOG5030J61">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_637620_0_0_11"/>
    <dbReference type="OMA" id="NAAMERY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="430" mass="42669" checksum="F5CC154F176BACA6" modified="2010-04-20" version="1">MAKSSITFEELYWMQVQDVDKAGANSGTFGDGMRSHAKKIEQLEGRVPSYYRSQDGKLLQDTLNIQAPPFRNAGGKFDDIAETLKHLSKDLSENQDKLKKVVEEANQNPFLEWRDKQNGVLAVKDLGPGGEENLTPREKQLYKEAVSKVDPLNARIKAAVKAARSADDRAAAKIESLGPNGEKGKKPTGGGEDGGGGQGGDDKGGSGEKPGEQDGGSEEEPGEQDGGPGDKPGDRPGEDPGSQYPGGDDPGSQDPGGQDPGSQYPGGDDPESQYPGDDGTGSDEWDPDDDYDGGGLADGGGVGGGLGSAGGGGASVGGGGLGSAGGGAGVAGGGVGGAAAGVPGGAIPVGANAAAAGRGGIGGIPMGGMMGGHGGGGEGGGSGEHTWLAEDDDPFGTGDAAPPVIGYVPPAPEPETGTKTDRSGSVTSFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Z9</accession>
    <name>D3Q6Z9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0685"/>
    <dbReference type="EnsemblBacteria" id="ADD40398">
        <property type="protein sequence ID" value="ADD40398"/>
        <property type="gene ID" value="Snas_0685"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0685"/>
    <dbReference type="HOGENOM" id="CLU_524699_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="519" mass="56044" checksum="9422CA25784040ED" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q716</accession>
    <name>D3Q716_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015986.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0702"/>
    <dbReference type="EnsemblBacteria" id="ADD40415">
        <property type="protein sequence ID" value="ADD40415"/>
        <property type="gene ID" value="Snas_0702"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0702"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_2_11"/>
    <dbReference type="OMA" id="SCDMVVC"/>
    <dbReference type="OrthoDB" id="1275789at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="260" mass="27067" checksum="9EFB43DCDC9634E4" modified="2010-04-20" version="1">MSDEVLSESADGVTTITINRPKALNALNVPVKVALREALAAAEADASCRAVVVTGAGDRGFCVGQDLREHAENLETGQGLSTVRDHYNPLATTLYEMNTPVVAAIRGTAAGAGASLAFLSDFRIGGPGTKFSMAFSGIGLAADTGASFALPRLIGRAKAAELLILNTPVDATESLRLGLLTQVTETDDDVLPRAQQLAAHLAAGPTVAYGWIKQQLRVDGGFAASLECEAQAQQACGETSDHAKATADFVNKRKPTFEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q729</accession>
    <name>D3Q729_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0716</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40428">
        <property type="protein sequence ID" value="ADD40428"/>
        <property type="gene ID" value="Snas_0716"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0716"/>
    <dbReference type="eggNOG" id="ENOG5031UQM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_186189_3_2_11"/>
    <dbReference type="OMA" id="KILMWAG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="50" mass="5174" checksum="1F938017BEEFE537" modified="2010-04-20" version="1">MKKILMWAGVAFLVFFVAFRPDDAGNVVGNIAGTIGAIGEGFATFIAGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7D0</accession>
    <name>D3Q7D0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2725</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2725"/>
    <dbReference type="EnsemblBacteria" id="ADD42401">
        <property type="protein sequence ID" value="ADD42401"/>
        <property type="gene ID" value="Snas_2725"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2725"/>
    <dbReference type="eggNOG" id="COG2223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033198_0_1_11"/>
    <dbReference type="OMA" id="WWYYARR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17341">
        <property type="entry name" value="MFS_NRT2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="PTHR23515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="457" mass="48606" checksum="73789BDE4AC52361" modified="2010-04-20" version="1">MTMTNAPEKRRWITDWNPDDETFWRAGGARVARRNLIWSILAEHLGFSVWLLWSVVVVSLPAAGFDFGVDQLFWLVAVPNLFGAFMRIPYTAAVARFGGRNWTTVSAALLLVPLGLLTYCVTTPGTPYELFLLAAITAGFGGGNFASSMANISYFYPDRYKGTALGLNAAGGNIGVAVVQFLVPLVIGVGVIGTAQSDGLWLHNAPLLWIVPVVVAAVCAWRYMDNLAVSRTPLRVQLRALRSKHCWIMSGLYIGTFGSFIGYSAAFPLVIKAEFPDMSALWLAALGPLVGSVARPFGGWLSDRSTGARVTNWSFAGMGLGAISAVAALSVGSFGWFFASFLALFVLSGVGNGSTFRMIPAIYRAEAATSDGPEATAALDLARKRSAAVIGFSSAVGALGGFAIPRGFGASLAATGSVDTALLVFVVVYAGCGVANWWFYQRTVLTTRLPSLAHARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q893</accession>
    <name>D3Q893_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thiamine pyrophosphate protein TPP binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2791</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018038.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2791"/>
    <dbReference type="EnsemblBacteria" id="ADD42467">
        <property type="protein sequence ID" value="ADD42467"/>
        <property type="gene ID" value="Snas_2791"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2791"/>
    <dbReference type="eggNOG" id="COG0028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_3_0_11"/>
    <dbReference type="OMA" id="WGFAIAK"/>
    <dbReference type="OrthoDB" id="351701at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="6">
        <location>
            <begin position="4"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="4">
        <location>
            <begin position="191"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="5">
        <location>
            <begin position="394"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="576" mass="61035" checksum="BEDFCB1DA987C0FC" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8C0</accession>
    <name>D3Q8C0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2818</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018065.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2818"/>
    <dbReference type="EnsemblBacteria" id="ADD42494">
        <property type="protein sequence ID" value="ADD42494"/>
        <property type="gene ID" value="Snas_2818"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2818"/>
    <dbReference type="eggNOG" id="COG0609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013016_1_0_11"/>
    <dbReference type="OMA" id="VFIWIVR"/>
    <dbReference type="OrthoDB" id="1283908at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="344" mass="34877" checksum="44EAD144A3365F61" modified="2010-04-20" version="1">MTSTRLAERTKPARAPRRGLGLALAVLALAGACVLSLGVGAKAIPASDVIAAILDPDNGAEAPIVWSLRIPRTLMGLTAGAALGACGALIQALTRNPLADPGILGVNAGAAFAITMAIAFLGLSSPWGYVWFAIAGAFVATLAVYAIGSIGRAAATPVRMTLAGVAMSAVLAGVTQIVSLTNPRLFHSSLSWTVGSLGGRDLGIIAALAPLVGIGLVLAVLVTKPLNAWALGDDLGRSLGGNPNRVRVITITAITVLAAAATALAGPIGFVGLIVPHVVRWFTGPDQRWIVALSVVVAPVLLLVADSLGRILLPNGELRVSIVTAFLGAPLMMGLVMRRKASSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8G7</accession>
    <name>D3Q8G7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Streptogramin A acetyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2866</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018112.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2866"/>
    <dbReference type="EnsemblBacteria" id="ADD42541">
        <property type="protein sequence ID" value="ADD42541"/>
        <property type="gene ID" value="Snas_2866"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2866"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_5_3_11"/>
    <dbReference type="OMA" id="KGTHSYY"/>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="23873" checksum="B3461D85D753F3A2" modified="2010-04-20" version="1">MSPDPMTVRPTPHERVVFLKPLINSEKIVVGDYTYYDDPDDPTAFEERNVLYGYGPEKLVIGKYCALATGTRFIMAGANHPTAGVSTFPFTIFGGEWAEKTLDVLSAIPSRGDTIVGNDVWFGYQSLVMPGVRIGDGAIIASGSVVTGDVAPYSVVGGNPAKQIRRRFSDTEVEQLLDAAWWDWPMELVTEHARTIMAGNPADIARVAAEHRRPQEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8L5</accession>
    <name>D3Q8L5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">zf-RING_7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020028.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4816"/>
    <dbReference type="EnsemblBacteria" id="ADD44457">
        <property type="protein sequence ID" value="ADD44457"/>
        <property type="gene ID" value="Snas_4816"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4816"/>
    <dbReference type="eggNOG" id="COG1579">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073076_0_0_11"/>
    <dbReference type="OMA" id="CQGCRQE"/>
    <dbReference type="OrthoDB" id="833439at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003743">
        <property type="entry name" value="Zf-RING_7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02591">
        <property type="entry name" value="zf-RING_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-RING_7" evidence="2">
        <location>
            <begin position="203"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="58"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="245" mass="27568" checksum="06EF9A791880C024" modified="2010-04-20" version="1">MRANPADQRRLLDLQQADTSLTQLAHRRANLPEEAEIVTLRQQVNELADRAGSNEATVGDLDRDIAKVEREIDQVRRRADTDRERQASGKLGPKELEGIAHELETLARRQSELEDQELDLMEQREQKQAAAEADARDLADKRTALAEIEKRRDEALAAIDAELAAERSTREGISVDIPEDLRKLYEKIRRTKPIAAALLRQRRCESCRLEQSGAELADLRAADESDVVRCDNCGAILVRTEESGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8R0</accession>
    <name>D3Q8R0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
            <ecNumber evidence="2">3.5.1.32</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.32" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020073.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4861"/>
    <dbReference type="EnsemblBacteria" id="ADD44502">
        <property type="protein sequence ID" value="ADD44502"/>
        <property type="gene ID" value="Snas_4861"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4861"/>
    <dbReference type="eggNOG" id="COG1473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023257_0_1_11"/>
    <dbReference type="OMA" id="GLHNAPE"/>
    <dbReference type="OrthoDB" id="796259at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047980">
        <property type="term" value="F:hippurate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="191"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="396" mass="41683" checksum="45499C31669BD612" modified="2010-04-20" version="1">MNLREESAAIAADLVALRRRLHRIPELGLDLPKTQAVVLEALSGLPLEVSTGEVLSSVTAVLRGGRPGPTVLLRGDMDALPVAEESTQPWRSEHDGSMHACGHDLHTAGLIGAARLLSAHQDELAGNVVFMFQPGEEGHDGAAHMIAEGVLAAAGGPVDAAYGIHVFSSMLPKGVFASRPGPLMAASDGLFVTVTGSGGHGSRPHDALDPIPVACEMVTALQTMVTRRFDAFEPVVLTVGVFNAGTRRNIIPDEASFEATVRTFSSEIGDQIAEYAVKTCQDIAAAHGMRAEVRYDREYPATVNDAAETDFAAATVREVFGEDRYATLPNPLMGSEDFSRVLAAVPGAYVFLGACCDEDPAKAPTNHSPRAAFDDSVVADGAALLAELAVRRLARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8R4</accession>
    <name>D3Q8R4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020077.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4865"/>
    <dbReference type="EnsemblBacteria" id="ADD44506">
        <property type="protein sequence ID" value="ADD44506"/>
        <property type="gene ID" value="Snas_4865"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4865"/>
    <dbReference type="HOGENOM" id="CLU_939798_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="296" mass="31202" checksum="81542478B8666D82" modified="2010-04-20" version="1">MNQQYPYPDGPGYGSQPDQEPVPTASYDLEPQPGYDPTSSMQVMGTPPQQPGYGPPPPGAMPPSPPPKKSSTGLIVGLGVGVIVLMLLGGAAVWFFLLGGPGGGGPGGADSADGKQNPFPDSYTSTEAPPPDGETWAMSKPESYDKCVDLNLTGVEKVIPFEGNPEGTTTPDGENTGRMVCEATMVGETNDAGYHPTGTFYVDFDAAKDATEAGEEYAKIWDIATGYGDGKKLDIGEEAEVRTKLDNNVRDVAIAYRVGNVTGLARISVNFSTHFKEPDQQMLTNVLTDVIYSGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8R8</accession>
    <name>D3Q8R8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020081.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4869"/>
    <dbReference type="EnsemblBacteria" id="ADD44510">
        <property type="protein sequence ID" value="ADD44510"/>
        <property type="gene ID" value="Snas_4869"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4869"/>
    <dbReference type="eggNOG" id="COG1022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_45_5_11"/>
    <dbReference type="OMA" id="GWIAPHC"/>
    <dbReference type="OrthoDB" id="164380at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="23"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="600" mass="64594" checksum="E6DB3F5C9EAEC113" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8S6</accession>
    <name>D3Q8S6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ste24 endopeptidase</fullName>
            <ecNumber evidence="12">3.4.24.84</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Snas_4877</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7 8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.84" evidence="12"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020089.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4877"/>
    <dbReference type="EnsemblBacteria" id="ADD44518">
        <property type="protein sequence ID" value="ADD44518"/>
        <property type="gene ID" value="Snas_4877"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4877"/>
    <dbReference type="eggNOG" id="COG0501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025947_1_1_11"/>
    <dbReference type="OMA" id="LPFKIYK"/>
    <dbReference type="OrthoDB" id="1918093at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07343">
        <property type="entry name" value="M48A_Zmpste24p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027057">
        <property type="entry name" value="CAXX_Prtase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032456">
        <property type="entry name" value="Peptidase_M48_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16491">
        <property type="entry name" value="Peptidase_M48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 7 8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48_N" evidence="11">
        <location>
            <begin position="100"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="10">
        <location>
            <begin position="214"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD44518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="417" mass="43441" checksum="C59158D3B08D036E" modified="2010-04-20" version="1">MVAFLRQPAAIALLVLLGALLIAGALLVPWGDPPVPSAAAQAKAVDSLPAGVVATGKEFAAALRPGSYIALGLSLAVALLLGLTTLGAKLVALGGRPFGGHWLAEAVLGGLLVVLVSQVVTLPLSAWSHSIRVRFGMSTQSWGQWAMDVGKSYLVTIVLSALALAAFYTVIRFAPKWWWAWTAVGAGLLVVVMSALYPLVIEPVFNSFKPMGDSALRTELMDMAEADGVPVKDVLVSDASIRTNAVNAYVSGLGPTRRIVVYDNLLKAPDKEVASVVAHELGHAKANDVWIGTALAALGTAAAVCAIALLANATGLLRRAGADTITSPRALALILAFVAVVGLLTTPLQSAVSRRMEMRADAHALELTKDPATFAEMQANLAASNKSDVDPPGIIHWLFGSHPTTAQRIAMAKAYGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8T9</accession>
    <name>D3Q8T9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020102.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44531">
        <property type="protein sequence ID" value="ADD44531"/>
        <property type="gene ID" value="Snas_4890"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4890"/>
    <dbReference type="HOGENOM" id="CLU_1958244_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="142" mass="14717" checksum="549BDAB305457D1D" modified="2010-04-20" version="1">MSDDVFVDFDGDGAGDEYETETLDDGSTAYISEDGEVAVDENGDGIIEELYTDEDGDGNLDTQMSDLDGDGYVDTEASFEGDPLGEEETKGEESSDDKSGEGEKSGEGESGGEKTEDDKSGEGESGGSNSEGKGEGGLDSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Z8</accession>
    <name>D3Q8Z8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tryptophanyl-tRNA synthetase</fullName>
            <shortName evidence="8">TrpRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">trpS</name>
        <name evidence="10" type="ordered locus">Snas_0896</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tryptophan to tRNA(Trp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016178.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0896"/>
    <dbReference type="EnsemblBacteria" id="ADD40607">
        <property type="protein sequence ID" value="ADD40607"/>
        <property type="gene ID" value="Snas_0896"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0896"/>
    <dbReference type="eggNOG" id="COG0180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029244_1_1_11"/>
    <dbReference type="OMA" id="GWGQFKP"/>
    <dbReference type="OrthoDB" id="951354at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00140_B">
        <property type="entry name" value="Trp_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024109">
        <property type="entry name" value="Trp-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="205"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="21"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="30"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="157"/>
            <end position="159"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="205"/>
            <end position="209"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD40607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="344" mass="38276" checksum="165615F4F8E56F55" modified="2010-04-20" version="1">MTSTEPATEAVRRPRVLSGIQPTADSFHLGNYLGALRNWVAMQDTHDAFYCVVDLHAITVDHDPKLLRKRSRIAAAQLLAVGIDPARSTLFVQSQVPEHPMLSWILECHTGFGEAGRMTQFKDKSAKNERVSVGLFTYPILQAADILLYRADAVPVGEDQRQHLELSRDLAQRFNTKYGNVFTVPEAHIIKATGTIQDLTEPARKMSKSNSQPAGIIDLLDDPNRIRKKIKSAVTDTGREIVFDPENKPGVSNLLTIYSSLTETSIEELQNRYADSGYGDFKKDLAEIVADFCAPIAQRTKSYLDDTAELDKILLAGAEKAHSVAAHTLARVYRKMGFREPVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q906</accession>
    <name>D3Q906_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0904</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016186.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0904"/>
    <dbReference type="EnsemblBacteria" id="ADD40615">
        <property type="protein sequence ID" value="ADD40615"/>
        <property type="gene ID" value="Snas_0904"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0904"/>
    <dbReference type="eggNOG" id="COG3568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060500_5_0_11"/>
    <dbReference type="OMA" id="MTFNIQS"/>
    <dbReference type="OrthoDB" id="1387978at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049657" evidence="1">
        <location>
            <begin position="41"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="54"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="289" mass="32289" checksum="4BF810639F2A0A40" modified="2010-04-20" version="1">MSNRRLTWSRRSLLNGAVGAAVVLGLTGSTGPAEPFPRSAADRRTGNDKWLRAASFNIHHGASPDDVLDLERIARRIEALNVDVIGLQEVDRFWKRSDHVDQPAWLSRRLGLHVAFGLNELRRSDGAGRRREYGTAILSRWPIRETRNVALPRWDDHARHGLLRTEIDMPGGSLSFATTHLIHAHHDEERAAQAKAVAKQFADDARRSVVVGDFNDEPNTPAIAAMTRRFTDAWAVAGSGKGYSYSSTKPKRRIDYVFGSEDLEPRAMTVDDTDPRASDHLPILTEFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q978</accession>
    <name>D3Q978_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0977</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016258.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0977"/>
    <dbReference type="EnsemblBacteria" id="ADD40687">
        <property type="protein sequence ID" value="ADD40687"/>
        <property type="gene ID" value="Snas_0977"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0977"/>
    <dbReference type="eggNOG" id="ENOG50340C1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134851_0_0_11"/>
    <dbReference type="OMA" id="LTDQWRD"/>
    <dbReference type="OrthoDB" id="1989840at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="133" mass="14771" checksum="5D0D5C757B399517" modified="2010-04-20" version="1">MAVKPSQRWREGVAEEAEELAAGTLDPECAHRSMLFPEPMIQATDAVLATFETEVTQLSDPTDGQVFACVKRVVLALNAANERFGGAAYETDEREALCAYIDQTLTEHGIDIPALAERRGINPHEITDAWRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9F4</accession>
    <name>D3Q9F4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018207.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2961"/>
    <dbReference type="EnsemblBacteria" id="ADD42636">
        <property type="protein sequence ID" value="ADD42636"/>
        <property type="gene ID" value="Snas_2961"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2961"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1060831_0_0_11"/>
    <dbReference type="OMA" id="RLPDLWQ"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="155"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="255" mass="27380" checksum="0B40E73F91055F80" modified="2010-04-20" version="1">MLIDGGAAVSIGLDDPPHVVQAGVGVHGVQSRTDVFRLPDLWQLHLYQYEGVLSLGGRSHDIRPGRVSLIPPATTVEFSYRGRSEHLYAHFRAASGVAVPVMQDAATAAPLLCGLLSEAVRERGSVAAHAAVWAALWKVANLPSDTGHLGHAAVRVAMDHIEWRLAEPMTVPQIADAAGISHNHLTRLFRAETGTSVVGYIRARRMGRAEHLLTETTVPIATVAATVGIPDLQAFNKICRRELGASPSRVRARGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9L8</accession>
    <name>D3Q9L8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type I phosphodiesterase/nucleotide pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4923</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020135.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4923"/>
    <dbReference type="EnsemblBacteria" id="ADD44564">
        <property type="protein sequence ID" value="ADD44564"/>
        <property type="gene ID" value="Snas_4923"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4923"/>
    <dbReference type="eggNOG" id="COG1524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039939_0_0_11"/>
    <dbReference type="OMA" id="LMNQLRW"/>
    <dbReference type="OrthoDB" id="191097at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="391" mass="41544" checksum="85CD459F19E4A16A" modified="2010-04-20" version="1">MEIDAELYEPASPRYGEAALSDILPSVLAALKVPDGNDVLGLADAELADIRRVVVLLVDGLGYHLLREAAASSEYLAAAVDGELGTLRELTTNYPSTTPTSIASLNTGVAPGQHGLTGFTVNIPGTEDMLTHIAWGPDGPDPRSWQPVPTCYERAAAAGVATTIVHRPEFVDAGLTEAIFRGGAIAPADSLAETAQEVHKALSQGDRSLVYCYYGYVDKRGHGYGPGSAPWHAAVANVNRLLRLITNGLPADAALLVTADHGMIEVPREDHIDLADHPHLRDGVRLVVGEPRSRYVHTRPGAVADVAAAWRETLGDRVEVLTRDEAVATGRFGTVTPEHLPRIGDVVVTGNRRHVIIGGDSDIPPLNSFVGFHGGLTAAELAIPLWSYRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9T8</accession>
    <name>D3Q9T8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histone family protein DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4997</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4997"/>
    <dbReference type="EnsemblBacteria" id="ADD44634">
        <property type="protein sequence ID" value="ADD44634"/>
        <property type="gene ID" value="Snas_4997"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4997"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085366_1_0_11"/>
    <dbReference type="OMA" id="ALAVHFD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="85"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="19959" checksum="93CD86E782FC88D2" modified="2010-04-20" version="1">MNKAEFIDALVEHLGDRKTALKALDAMLEEIQRAVSKGEKVSFAGFGVFEKRQRAARMARNPRTGEAVRVKKTVVPAFRPGQGFKELVTGEKKMPKRSTGKKSTARKTTAKQTAPAKKSTTRKAAAKKTVRTASKAAKSVTKRVGATKKTAAKKSAKKASRGRLSINPSGSSVRPTSDHQKRGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Y7</accession>
    <name>D3Q9Y7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0989</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016270.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0989"/>
    <dbReference type="EnsemblBacteria" id="ADD40699">
        <property type="protein sequence ID" value="ADD40699"/>
        <property type="gene ID" value="Snas_0989"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0989"/>
    <dbReference type="HOGENOM" id="CLU_672519_0_0_11"/>
    <dbReference type="OMA" id="FMDSIPW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="149"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="362"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="409" mass="36990" checksum="882CA5CA40E9DED6" modified="2010-04-20" version="1">MDYGQLLGLDVGAIFEAAGGSAALRDVYGDGVSAVNGQVSSMPGAWGGDDAESAISSIAGNIRPLDETSTAFDKAQRVLNALGQNMTELQVELNALDKQVSAVPGTVDPTSGVVTPTATTPQAVAAATALTTAIQGVLARANAADQAAAAQLQDQPSGVDSGGGNGGGDGRTSSSGGGSSSGGGSMSGASQSGAGGQQSGGGSAGGGQSGGGSAGGGQSGGGSAGGQQSGGQYGGDSLASAGQNALSSAGSYGGGSFGGGSTAAGGNPGGSFGGGSYGGGGYGGGGGGAYGGGSYGGGAYGGGSSGGGARSAGMGSAGGSTKASNAFSQAGGAAANGAALAAGRGMMGGGMGGGFMGGGMGGRGAGDGGGGAATANSWLHEDRDPFTTDDAAPPIVGGATKRVTESTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA62</accession>
    <name>D3QA62_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenylate/guanylate cyclase with TPR repeats</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1064</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the adenylyl cyclase class-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016345.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1064"/>
    <dbReference type="EnsemblBacteria" id="ADD40774">
        <property type="protein sequence ID" value="ADD40774"/>
        <property type="gene ID" value="Snas_1064"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1064"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3899">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004435_0_1_11"/>
    <dbReference type="OMA" id="GYPRAHE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="3">
        <location>
            <begin position="40"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="776"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1226" mass="129622" checksum="273D10732959041E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA67</accession>
    <name>D3QA67_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016350.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1069"/>
    <dbReference type="EnsemblBacteria" id="ADD40779">
        <property type="protein sequence ID" value="ADD40779"/>
        <property type="gene ID" value="Snas_1069"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1069"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040940_3_1_11"/>
    <dbReference type="OMA" id="WERPWDR"/>
    <dbReference type="OrthoDB" id="1623169at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:CoA pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="CoAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="PTHR12992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="39"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="213" mass="23175" checksum="B505DAB20DD81CEC" modified="2010-04-20" version="1">MTTPRPLTDVELPDWWHPLAEKAASVDGRDITRYLPTEGQGRPAGILILLGADENGPNVILTQRAATLRQHAGQPSFPGGVADPEDASIVDTALREANEEIGLDPDSVTVVTTLPELWLNVTDHRVTPVLAWWHAPHPIAVVDPAEVASISKLPVRDLVDPANRVRYRHSSGYVGPAFEIDGMLVWGFTAGVLSAVLRLAGWERPWEPGRLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAD2</accession>
    <name>D3QAD2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3044"/>
    <dbReference type="CAZy" id="GH39">
        <property type="family name" value="Glycoside Hydrolase Family 39"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42715">
        <property type="protein sequence ID" value="ADD42715"/>
        <property type="gene ID" value="Snas_3044"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3044"/>
    <dbReference type="eggNOG" id="COG3664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049286_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049003" evidence="1">
        <location>
            <begin position="37"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="369" mass="40239" checksum="971DA3EF9D5C41DE" modified="2010-04-20" version="1">MRVFPLLGGRRRRAAVASAGALVLAVVGYTAATASADTNADFQVGYTHNNTAFPFGDDDATASAKEILSGTGPIQNQHLMGFGTDNPWPKQDGPRDFSSLEERLAAIKSTDGKPVITLCSAPGWMKPSGDDWEMNEAPKPEYYDEFAQLAAETAQKFPEVEYFQVWNEFKGFWNGSEPDYVEFTKFYNQVYDAVKEVRPDAKIGGPYVTLRNEYGQPGDSEVSGEWGEVNPGDIEAVRYWNENKSGAEFFTLDAWTIDGDGDALDPAQMKQMFSDVTAFFAAESGLPVWWSEYYAPLSGPKPGDDVDPTTPEAVTAALEGMRDGGASVALWWQPECGEGPHPCVFTDTSQAGGGKRTEFTEVAEAFSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAD3</accession>
    <name>D3QAD3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018287.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3045"/>
    <dbReference type="EnsemblBacteria" id="ADD42716">
        <property type="protein sequence ID" value="ADD42716"/>
        <property type="gene ID" value="Snas_3045"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3045"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="AYDCIDV"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="36313" checksum="C7849CA761651318" modified="2010-04-20" version="1">MEYLRLGSTGLKVSRICLGMMSYGDPAHRAWSLPLDDARPIVKHAVDSGITFFDTADMYSRGASETITGQLLSELFADREDYVLATKVYFPMSERPNDSGLSRKHIMASIDASLKRLGTDYVDLYQIHRWDYQTPIEETMEALHDVVRAGKARYIGASSMYSWQFAKAQYVAEANGWTKFVSMQNQVNLVYREEEREMLPLCADQGVGVIPWSPLARGLLAGTRERGGTANTVRAGSDPVIDVLYSDNDFDIVDVLREVAAKRDLPPAQLALAWVLRKPEVTAPIIGATKTKHLDDAIAAVDVELGDEEVTALETPYRPRPISDHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAH2</accession>
    <name>D3QAH2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3084</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018326.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3084"/>
    <dbReference type="EnsemblBacteria" id="ADD42755">
        <property type="protein sequence ID" value="ADD42755"/>
        <property type="gene ID" value="Snas_3084"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3084"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035309_1_0_11"/>
    <dbReference type="OMA" id="MPMAGRV"/>
    <dbReference type="OrthoDB" id="1809199at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="12"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="415" mass="41794" checksum="7F048427F3194616" modified="2010-04-20" version="1">MRNPFTPRAEPALVRARVGVFGYFATSGFVMGTWAAGLPAVDERLHLGPGRLGTALLLIAGGALVSMLVVGRVSDRFTSRVVARISGPVAALLLLGPVLAPSYSWLLICSAVYGISVGFIEVSMNVNSIEVEVRYGRPIVSAFHGLWSLGGAAGGALTTAGLHAHLDPQAMLIGFILLSTVAFGYFGRMLLPPPSRPEPDPATAGAKPGRGLGIGMGIVLLLGIVAFGGHLAEGAAIDWAAIHARRVLDTPLSNAPIAYTVFGTAMTLVRLAGDPIRSRLGPGRTLLLAGVLSTAGYGLVLLSPVAGGAGLVVACVGWALTGMGLATVVPVVFSAIGAAHGAVGKALSLVTVFGSAGLLVGPAVIGHLAEATSLPTALIVPAVLAAVVALAGPSAIKALGLGRTTRPAEPVAEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAK5</accession>
    <name>D3QAK5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridoxal-5'-phosphate-dependent protein beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3117</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3117"/>
    <dbReference type="EnsemblBacteria" id="ADD42788">
        <property type="protein sequence ID" value="ADD42788"/>
        <property type="gene ID" value="Snas_3117"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3117"/>
    <dbReference type="eggNOG" id="COG1171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021152_4_2_11"/>
    <dbReference type="OMA" id="VKHENHT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901607">
        <property type="term" value="P:alpha-amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="29"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="329" mass="34947" checksum="DED248066ED02860" modified="2010-04-20" version="1">MNLADTRFMRIPDFNDFLLARRRLRERLAPTPLLSYPALDELTGVRVLIKHENLQPIGAFKVRGGLTLLSTMNESDRARGVVTYSTGNHAQSMAYAARAFGVPCVISMPANPNPVKAAAVRRLGAELITEGADLEGAREHAEAIASQRGMRLVSAANEPDLIAGVATTYVELCETAPGLDAVIVPVGSGTGAAAACLTIATMNPTCQVIAVQSSASPAAHDSWREGHCVRRPNKTVAEGLATGEGFTLPQEILRDRLTDFLLVDDAEIQQAQWRLMSVARTVAEGAGAAAMAALWKSREQLAGRKVAIICSGGNASQSELRDCLTSAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAM3</accession>
    <name>D3QAM3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Small ribosomal subunit biogenesis GTPase RsgA</fullName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rsgA</name>
        <name evidence="7" type="ordered locus">Snas_3135</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3135"/>
    <dbReference type="EnsemblBacteria" id="ADD42806">
        <property type="protein sequence ID" value="ADD42806"/>
        <property type="gene ID" value="Snas_3135"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3135"/>
    <dbReference type="eggNOG" id="COG1162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033617_0_1_11"/>
    <dbReference type="OMA" id="RFHDCAH"/>
    <dbReference type="OrthoDB" id="908180at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01854">
        <property type="entry name" value="YjeQ_EngC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01820">
        <property type="entry name" value="GTPase_RsgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004881">
        <property type="entry name" value="Ribosome_biogen_GTPase_RsgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010914">
        <property type="entry name" value="RsgA_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32120">
        <property type="entry name" value="PTHR32120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03193">
        <property type="entry name" value="RsgA_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00157">
        <property type="entry name" value="TIGR00157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50936">
        <property type="entry name" value="ENGC_GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CP-type G" evidence="6">
        <location>
            <begin position="100"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="ENGC_GTPASE" evidence="5">
        <location>
            <begin position="108"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="333"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="147"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="199"/>
            <end position="207"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="359" mass="37800" checksum="C68AFD94B0A96B54" modified="2010-04-20" version="1">MASLGWDATFSDSYSRYDRRGNHPGRVARVDRGVCTVLTAGGTVRASLAGRMLGVVAKDPLSMPSVGDWVVVRTWDDDRRTIEAVLPRRSAIVRSTAGKAAEGQAIAANADAVAIVEALDPDPDFGRIERLAALAYDSGATPLLVLTKADAVPDPELLADDLSAAMPDAPVLTVSAVTGQGLDALAEYLKPGRSLALLGASGAGKSTLVNALAGAEVMATRGLRADGRGRHTTSHRSLVPVPHGGAIIDTPGLRVVGLFDRRPGDAATPVDGLARAFGDLDALAAQCRFNDCRHDTEPGCAVLAAIDDGLLTARRLENWRKLQREQAFERSRAAARARAVGRDKARHRAAQDKARARGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAN8</accession>
    <name>D3QAN8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Platelet-activating factor acetylhydrolase plasma/intracellular isoform II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5047</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020255.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5047"/>
    <dbReference type="EnsemblBacteria" id="ADD44684">
        <property type="protein sequence ID" value="ADD44684"/>
        <property type="gene ID" value="Snas_5047"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5047"/>
    <dbReference type="eggNOG" id="COG4188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026278_1_0_11"/>
    <dbReference type="OMA" id="MIMAHEG"/>
    <dbReference type="OrthoDB" id="685252at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005065">
        <property type="entry name" value="PAF_acetylhydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PTHR10272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
        <property type="entry name" value="PAF-AH_p_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049832" evidence="4">
        <location>
            <begin position="28"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="370" mass="40861" checksum="F325A8E603AEC263" modified="2010-04-20" version="1">MRRRLLGLAAVAAVAAAGLAVVPPANAATAERPELLEPTGQHRVGRTDLHLVDEGRADPWMPDQDRELMVSLYYPARKNSGKPTEYMTYDESKGYLEQEELDLPPETLNTVKTYAYQDAKPLPGKKRPLVLLSPGWTKPRATLTGIAEELASKGYIVAVMGHNYESVTQFPDGTLTKCEACGRNELDKASQGRAKDASFVIDELTDRRGPWRGSQWIDADRIAMSGHSLGGGASYEALRDEKRIKAVASLDSRIYEPGAFAVDRPLLLLGSAKRTSEHPDDPWHQAWDNASGWKRWISVDGTAHSSFTDVGLLGPQVGVTDPEQTLEPERCTELTRDVVSAFFDKHLKGKNRPILDGPTDDYPELKFRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAU7</accession>
    <name>D3QAU7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5108</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020314.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5108"/>
    <dbReference type="EnsemblBacteria" id="ADD44743">
        <property type="protein sequence ID" value="ADD44743"/>
        <property type="gene ID" value="Snas_5108"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5108"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="AWFMAQF"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="23"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="480" mass="50379" checksum="396983B7D586EB6C" modified="2010-04-20" version="1">MTAPAAVTATSTADGGAARRGPMLATLLIAWFMAQFDFFVVNVAAPSLSHNLNVTPAALELVVGGYAFTYAAGMITGGRLGDRLGHRRMFVYGMAAFTLASVLCGLAMNPGQLIAFRLLQGLTGAAMVPQVLALITATFPVAERPKALGWYALTGGLASISGQVLGGLLVDVNLFGLEWRTIFLINLPIGLLTVPLALKLLPRHTPGARIGLDPVGAIGMALTLGAVLVPLGLGNSQHWPLWTWLSLGAAVPLAVFTVWWQRRLHRGGGQPVLELALFKVKTYAAGMAAGAAFMVYWAGFMFTLALLLQSGYEFTAFQAGLCFLPMGVLFSTAALAGGRLVRRFGLRVPLTGSIIVLIGLLVAIAAMWTSTDAANLPLLIVGFSIMGTGNGLLLPQLVSASLTEVRREQAGIGAGMVATSQQFAQAAGAAILGAVFFAVVHNREGLAAYDTAMERVLYIDLGLLAVVASLVIYLHRHAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB12</accession>
    <name>D3QB12_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016400.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1119"/>
    <dbReference type="EnsemblBacteria" id="ADD40829">
        <property type="protein sequence ID" value="ADD40829"/>
        <property type="gene ID" value="Snas_1119"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1119"/>
    <dbReference type="HOGENOM" id="CLU_896901_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="33810" checksum="FA9D50BD44E43692" modified="2010-04-20" version="1">MPDLRELLDRALPDAWEAAGSSVDAAMARGSRIRRRRRIASTAAIVGSFLAVVLVASSVVGMWRGDESPPADSLKGSPAFELPALDSGELYYWDAYPESSDEESELLEPYDKALDDFLIAGDSVLLDPGESVNFSREGRKLMRDNGGDYYTSTVGDKIVHKQPVYYTTFDSPDGESVYVDVIPRGGFTAGSTRDADWETEGDYMGGGDDATYLIACGEHLEGDGKATYDEVTAECEEVTDSTGQEVVRGLETRVSKDDGDTYYYGRIVLYRDDGTAVRVRINSEQKKAGIPTLMDVMTELATALPSDPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB80</accession>
    <name>D3QB80_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplW</name>
        <name evidence="6" type="ordered locus">Snas_1187</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016468.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1187"/>
    <dbReference type="EnsemblBacteria" id="ADD40897">
        <property type="protein sequence ID" value="ADD40897"/>
        <property type="gene ID" value="Snas_1187"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1187"/>
    <dbReference type="eggNOG" id="COG0089">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037562_3_2_11"/>
    <dbReference type="OMA" id="FEVDHRA"/>
    <dbReference type="OrthoDB" id="1978865at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="104" mass="11624" checksum="9C8E276F52A5A720" modified="2010-04-20" version="1">MSTVSIPDPRDVIIKPVISEKSYGLLELNKYTFEVRKDANKSHIKLAVQEIFGVKVTSVNTLNRDGKRRRTRQGWGKRKDVKHAIVTVDGDAARLSEIFGGSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBC9</accession>
    <name>D3QBC9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Proteinase inhibitor I16 subtilisin-type inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_3140</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the protease inhibitor I16 (SSI) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018382.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3140"/>
    <dbReference type="EnsemblBacteria" id="ADD42811">
        <property type="protein sequence ID" value="ADD42811"/>
        <property type="gene ID" value="Snas_3140"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3140"/>
    <dbReference type="eggNOG" id="ENOG50345GU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121949_0_0_11"/>
    <dbReference type="OMA" id="MLYQPVT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000691">
        <property type="entry name" value="Prot_inh_I16_SSI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020054">
        <property type="entry name" value="Prot_inh_SSI_I16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023549">
        <property type="entry name" value="Subtilisin_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036819">
        <property type="entry name" value="Subtilisin_inhibitor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00720">
        <property type="entry name" value="SSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00294">
        <property type="entry name" value="SSBTLNINHBTR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55399">
        <property type="entry name" value="SSF55399"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00999">
        <property type="entry name" value="SSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 8" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 8" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048410" evidence="9">
        <location>
            <begin position="26"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="SSI" evidence="10">
        <location>
            <begin position="47"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD42811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="133" mass="13985" checksum="46141BC9B7FF19DA" modified="2010-04-20" version="1">MSKTILRLTGITIAAAGLVGLTATAAGAHEASQIGGSYHLTIRDNDGERAAATLTCYPHGGSHPRPYEACAQLEAVGGNVTAMSEDPGPCTMMWDPVTVRSEGLWGNTYSTYEETFANQCVAVRETGGVLFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBK5</accession>
    <name>D3QBK5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018458.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42887">
        <property type="protein sequence ID" value="ADD42887"/>
        <property type="gene ID" value="Snas_3217"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3217"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_20_1_11"/>
    <dbReference type="OMA" id="HPPIGGQ"/>
    <dbReference type="OrthoDB" id="867226at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="15"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="488" mass="53020" checksum="ADF0A804E8B5A6E0" modified="2010-04-20" version="1">MHTPPPSTDHEPDTFDVIIVGCGPTGAMLAAELRLHGIRVLVLETETGPTSFVRIVGLHIRSIELLAMRGLLDRVAPHARQRPAAGFFAAIDKPAPTGLDTAHPYLLGIPQPVIVRLLEEHATDLGARVQHGVAVTGVEPDDDGVTVTLDDGRCMRSRYLVGCDGARSTVRKQLGIAFDGQPAQTQTLMGEMEAGVAPDEIAAAMRRIGQGDRRWWLRPVGVGLYSVVVPAEGVTDRATPPTLEDVRRQLRAVAGTDFGVHSPRWLSRFGDATLLAERFRVGRVLLAGDAAHIHPPLGGQGLNLGVQDAFNLGWKLAAHIRGWAPVTLLDTYQAERRPVAADVLDNTRAQMALQGSEPGAQAMRRLVSELMDFDAVNRHLIAKITAIDIRYDFGDGPDLLGRRLPDLTTKQGRLYGLLHRGRGLLLDRTGRLGVGAWSDRVDYLPDPAAELNAACVLLRPDGHVAWIGDDQDDLDEQLARWFGQPNQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBL0</accession>
    <name>D3QBL0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3222</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3222"/>
    <dbReference type="EnsemblBacteria" id="ADD42892">
        <property type="protein sequence ID" value="ADD42892"/>
        <property type="gene ID" value="Snas_3222"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3222"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_40_0_11"/>
    <dbReference type="OMA" id="GRHFKDK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="17"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="204" mass="21965" checksum="08509D97FA7BC901" modified="2010-04-20" version="1">MVDAMPQATDERPYHHGNLRTALLEAAQASLREHGAAQLSLRDLAREVGVSHAAPRRHFPDRQALLDALAENGFTQLDTILRTACADAGDDFAARLRATMTAYTRFATDNAALLELMYTSKHRPGATAIVKAAEAPFQLMIELLQQGQAQGALPSGAPERIGIILFATLQGIASLINGNFVEADLLDELVDTAVEQFLHGARPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTY9</accession>
    <name>D3PTY9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015318.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0025"/>
    <dbReference type="EnsemblBacteria" id="ADD39747">
        <property type="protein sequence ID" value="ADD39747"/>
        <property type="gene ID" value="Snas_0025"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0025"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074072_1_1_11"/>
    <dbReference type="OMA" id="PLMYLRA"/>
    <dbReference type="OrthoDB" id="2063007at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="183" mass="19831" checksum="5C360CD7EC7D5445" modified="2010-04-20" version="1">MAERDIGGFIRDLRRNAKVSLRQLADQAGVSNPYLSQIERGLRKPSAEVLQQIANALKVSTPLMYLRAGLLKTKDGQGTLATIAGDPLLTARQKQTLTEIYEAFRRENARDAGLDLDDEASEPAVTDDEVAAAADGIPEEMGIDEPVDVSPSPKVKPAPQRRGARTRTRRTPAAPPTTNDTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU63</accession>
    <name>D3PU63_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Homoserine kinase</fullName>
            <shortName evidence="10">HK</shortName>
            <shortName evidence="10">HSK</shortName>
            <ecNumber evidence="4 10">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">thrB</name>
        <name evidence="12" type="ordered locus">Snas_1300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + L-homoserine = ADP + H(+) + O-phospho-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="4 10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016580.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1300"/>
    <dbReference type="EnsemblBacteria" id="ADD41009">
        <property type="protein sequence ID" value="ADD41009"/>
        <property type="gene ID" value="Snas_1300"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1300"/>
    <dbReference type="eggNOG" id="COG0083">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041243_0_1_11"/>
    <dbReference type="OMA" id="CANRIPH"/>
    <dbReference type="OrthoDB" id="610857at2"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="5 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="11">
        <location>
            <begin position="89"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD41009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="304" mass="31589" checksum="E1EE24393C82C514" modified="2010-04-20" version="1">MSKYSRDPVTVRVPATSANLGPGFDSLGLSLSIYDEVTARVVDARPGRTRVTVEGEGADTLPSTEDHLVAHSLRVAAEALGGHPPSVELHCRNAIPQARGLGSSSAAIVAGVSLAAHLMTQITPDPARLLAIASRIEGHPDNVAPCLLGGFTVAWSDGDAARAVSREVVSGLSPVVYVPDGHGFTVIARKALPKSVSHADAAFNVSRAALAVCAFTTDASLLLEATDDRLHQTYRAASMPHTAALVTQLRDEGIPAMISGAGPSVLAFTPDPPVYPGFELRKLTVGQGARRIDPRLAPQVLPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUF4</accession>
    <name>D3PUF4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">GTP 3',8-cyclase</fullName>
            <ecNumber evidence="3 12">4.1.99.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Molybdenum cofactor biosynthesis protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">moaA</name>
        <name evidence="14" type="ordered locus">Snas_3299</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>AH2 + GTP + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer and homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the radical SAM superfamily. MoaA family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.22" evidence="3 12"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018538.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3299"/>
    <dbReference type="EnsemblBacteria" id="ADD42967">
        <property type="protein sequence ID" value="ADD42967"/>
        <property type="gene ID" value="Snas_3299"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3299"/>
    <dbReference type="eggNOG" id="COG2896">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009273_0_1_11"/>
    <dbReference type="OMA" id="DYLRMSV"/>
    <dbReference type="OrthoDB" id="1199289at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019008">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01225_B">
        <property type="entry name" value="MoaA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013483">
        <property type="entry name" value="MoaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="Mob_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02666">
        <property type="entry name" value="moaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01305">
        <property type="entry name" value="MOAA_NIFB_PQQE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7 12" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="14"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="266"/>
            <end position="268"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD42967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="347" mass="38004" checksum="8ED87666B705BB0A" modified="2010-04-20" version="1">MATSDPLPTTVTDALGRPMGSLRVSVTDRCNLRCRYCMPEEEYAWLSSTDILSFDELTTVASAFTELGVDKIRLTGGEPLLRPGLDELIGKLATDERITDIALTTNGILLSGKASGLREAGLGRVTVSLDTLDAARFRELSRRGTHDAALAGIATAAEVFGSLKIDTVVMRGFNDDELVDLIEYGKTVSAEVRFIEYMDVGGATGWTEQQVYSRARIIEDLTAHYGHVTPLAKHDTAPADQFALPDGTVFGIISSTTQPFCGACDRSRLTADGMWLRCLYARTGTDLRGPLRRGADRDELAALIADIWRRRRDQGAVHRLDDDSRTVFVGLENLKRDPHLEMHTRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUG9</accession>
    <name>D3PUG9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ornithine aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ornithine--oxo-acid aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3316</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018553.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3316"/>
    <dbReference type="EnsemblBacteria" id="ADD42982">
        <property type="protein sequence ID" value="ADD42982"/>
        <property type="gene ID" value="Snas_3316"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3316"/>
    <dbReference type="eggNOG" id="COG4992">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_10_3_11"/>
    <dbReference type="OMA" id="DVFPRFA"/>
    <dbReference type="OrthoDB" id="572533at2"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050155">
        <property type="term" value="F:ornithine(lysine) transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine-oxo-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="PTHR11986:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="396" mass="42301" checksum="9109D893FC4488BB" modified="2010-04-20" version="1">MTGYIDLEAAHGAHNYHPLPVVLSHGEGAWVSDTDGNRYLDLLSAYSAMNFGHRHPRLVAAAKAQLDRLTLTSRAFHNDQLGPFIAELAALAEMDAVLPMNTGAEAVETGIKTARKWGYTRKGVAADRARIIVFDGNFHGRTTTIVGFSTDETARADFGPFAPGFDIVPYGDADALEAAITPDTVAILVEPVQGEAGVIVPPKGWLPRLRQLCDSNDMLLIADEIQTGLGRTGHTFACQREGVRPDIYLLGKALGGGIIPVSAMVADRAVMDVFAPGQHGSTFGGNPLASAVAREVVAMLATGEWQQRARDLEKHLVSALDRLDPTLVAETRVCGLWAGVELSAAAPPARTVCERMAAAGVLCKETHDTTVRIAPPLVIEPHEIDHAVDVMMQALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUW2</accession>
    <name>D3PUW2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyltransferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5352</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020557.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5352"/>
    <dbReference type="EnsemblBacteria" id="ADD44986">
        <property type="protein sequence ID" value="ADD44986"/>
        <property type="gene ID" value="Snas_5352"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5352"/>
    <dbReference type="eggNOG" id="COG3594">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047004_2_0_11"/>
    <dbReference type="OMA" id="DPLYLTW"/>
    <dbReference type="OrthoDB" id="1221455at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="3">
        <location>
            <begin position="31"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="399" mass="44174" checksum="100B1E38A7C3BD1B" modified="2010-04-20" version="1">MSTEVSARGETPTTGTNAKPATAKSGKDPLLDNAKVVLIVSVVCGHAWSPLLDDSHTVRAIYLTLYAFHMPAFVMLSGYLSRSYNGRESQRYRVVSTLIVPYVVFSLLYGAMRYWTEDELNPDLLNPFFQLWFLVALLVWRLTAPIWKLVRYPVLVALVISIGASTMDLPGELDLGRLLQFLPFFVAGLFLKRDHIDALRRPLPRIALATGAAAIVWAAFAFGGEVDRHWMYLNDGAKQLGLTFGEAFLMRIVLLACAVTLIAAFLALMPGKQRWYTALGAATMYPFLLHGFFVKIAEDGFKLYENDFINTGTGALTVTACAITLAALLLSRPIRWLTKPIVEPNLDWLLKRPLQAAKPRATPTPTPPPAPHPPTDVNHPRTPTYPDTKDAKETPPPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVF5</accession>
    <name>D3PVF5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018640.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3405"/>
    <dbReference type="EnsemblBacteria" id="ADD43069">
        <property type="protein sequence ID" value="ADD43069"/>
        <property type="gene ID" value="Snas_3405"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3405"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136758_0_0_11"/>
    <dbReference type="OMA" id="AWTREIL"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="21"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="162" mass="17953" checksum="1193BDC47AED7174" modified="2010-04-20" version="1">MPDNATEGDPRDPKPDEIADVVGFMPLIAAFFAKVRAEKPDEHSHSFADHGLTNRHAAVCVQLVAADGLSVTELANRMGLALSTVSELVGDLDRAQWVERQPDPGNRRRTLVSLRPDRREHMESVVTRRAEPLLKALDELTPGQREGFAAGLRAWARQLEAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVI2</accession>
    <name>D3PVI2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrogenase maturation protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A31 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018667.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3432"/>
    <dbReference type="EnsemblBacteria" id="ADD43096">
        <property type="protein sequence ID" value="ADD43096"/>
        <property type="gene ID" value="Snas_3432"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3432"/>
    <dbReference type="eggNOG" id="COG0680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099037_2_1_11"/>
    <dbReference type="OMA" id="DMEGFDR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023430">
        <property type="entry name" value="Pept_HybD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000671">
        <property type="entry name" value="Peptidase_A31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30302">
        <property type="entry name" value="PTHR30302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01750">
        <property type="entry name" value="HycI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53163">
        <property type="entry name" value="SSF53163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00072">
        <property type="entry name" value="hydrog_prot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="191" mass="19965" checksum="4DF14004F0D1EBCD" modified="2010-04-20" version="1">MIVVIGIGNPYRRDDGVGYEVIHRLETTGITARLATSDGEPTDLIDLWDGAELAVVVDAVRSGTARPGTIHELTTLPPSHGTGTASSHAIDIGDTFELARVLDRLPQRLVILAVEAADLSQGVGISADVAEAIPAVIDRVTTLAASRLSACHVWRLRHGRSVRHWGGASAASSYLRSVPALAPGVARGLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWI3</accession>
    <name>D3PWI3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Activator of Hsp90 ATPase 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018776.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3543"/>
    <dbReference type="EnsemblBacteria" id="ADD43205">
        <property type="protein sequence ID" value="ADD43205"/>
        <property type="gene ID" value="Snas_3543"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3543"/>
    <dbReference type="eggNOG" id="COG3832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108923_9_1_11"/>
    <dbReference type="OMA" id="LIEEWLM"/>
    <dbReference type="OrthoDB" id="1498264at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="147" mass="16824" checksum="28F27061B27EFE54" modified="2010-04-20" version="1">MDDARTIRVDQFLAHSPARVWRALTDPRLLGQWLMPNDFELSLGHRFTFTTNPIPSHDFDGRINCQVLDFESERMLRISWGGGKLDTTVTWKLEPEGRGTRLFVIHDGFDPDDPIQQLARRGMGSGWRSGVLRGLEKCLAELEHHGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWN5</accession>
    <name>D3PWN5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3597</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3597"/>
    <dbReference type="EnsemblBacteria" id="ADD43257">
        <property type="protein sequence ID" value="ADD43257"/>
        <property type="gene ID" value="Snas_3597"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3597"/>
    <dbReference type="eggNOG" id="COG3591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070813_2_1_11"/>
    <dbReference type="OMA" id="RWINIAD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="273" mass="30343" checksum="B40194B67C22F513" modified="2010-04-20" version="1">MKIVGIHGIRCYRPDPPLEAARYLETKWRQALEDNPVLKWPVRSIDFSISYYAHLLVQQGRQSDTDLDDAALQLLTELLAPWTPDAAGIQGRAMVLLRLAAARLAGKHGLEERTVWRFIRQFAAEVSYYLEGREGFTPRDTIIDATAKAIDKADIVIAHSLGTVIAYEALHRHRVAVPLLITLGSPLAIPAIVSRLKPPVINGRGRKPPSVKRWINLADCGDYIAIPINETDSINAVFDGIDEHNDSIRIGIFRSHGIEGYLRHPVLGRAVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX61</accession>
    <name>D3PX61_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HpcH/HpaI aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1621</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016895.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1621"/>
    <dbReference type="EnsemblBacteria" id="ADD41324">
        <property type="protein sequence ID" value="ADD41324"/>
        <property type="gene ID" value="Snas_1621"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1621"/>
    <dbReference type="eggNOG" id="COG2301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044864_2_1_11"/>
    <dbReference type="OMA" id="WDIHYLD"/>
    <dbReference type="OrthoDB" id="1107373at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH_HpaI" evidence="6">
        <location>
            <begin position="8"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="HpcH_HpaI" evidence="6">
        <location>
            <begin position="142"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="61"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="362" mass="37021" checksum="9E29B26423463713" modified="2010-04-20" version="1">MDTPIVTALYAPASRPELLPKAMASGADAVIVDLEDAVLAGRKEEARANVLAFLDGLAEADAGPSGSAELGERGTSADGSPSGSAEPSERSSSAGERGEGPAESAVERVPTIPVQRGRSGGSRERGAEAGARRSGPHCRPVVQVRVNHPRGEFGPRDLAALGAHPVVRAGRVAVRLPKVAGPQDVDLALDMLNVDAPLAVHCLLESAIGVEYARDIAAHPAVAGLALGEADLAAELGLRGEESFGWIRSRIVIAAVAAGLPAPAMAVYTDLADPRGLAESCARGRALGMFGRTALHPKQLSTITAAFAPDGVELRRAHEVVTAAAGAEADGSGAIALPDGRFIDAPMVESAKRTIQLAERLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX62</accession>
    <name>D3PX62_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TRAP C4-dicarboxylate transport system permease DctM subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1622</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016896.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1622"/>
    <dbReference type="EnsemblBacteria" id="ADD41325">
        <property type="protein sequence ID" value="ADD41325"/>
        <property type="gene ID" value="Snas_1622"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1622"/>
    <dbReference type="eggNOG" id="COG1593">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049437_0_0_11"/>
    <dbReference type="OMA" id="LPGWING"/>
    <dbReference type="OrthoDB" id="1128351at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004681">
        <property type="entry name" value="TRAP_DctM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33362">
        <property type="entry name" value="PTHR33362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="4">
        <location>
            <begin position="52"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="445" mass="45534" checksum="1D96439FABF86569" modified="2010-04-20" version="1">MLGIWALVAYIVVIIAWNGLLKRNIGEAMIIGFVAVAAFGGGSILEVGWAGIKAAATEEIVFAALTFVFMGFVLSKTGVVDQLIAMLNSLLGKRRGGAGYVSTIAAAMFGAVSGSGSGNAAAVGSVTIPWMAKSNFSPKLSATVVAGNAGLGIAIPPSSSLFILTGSAAVASYVTADQLFLALFAGGAWTLLYRLVLMFYFVRRDKIGAVDPSMIEPFGRTFAAGWSSLLVFVGIIVPVLLTSDLTSDAVISWIGEAPADAISIITWIPVLVTIIGLILGRRALPRRGTDWWKLLGEVGPRYAVIGATLFFAFAAAATLTELGLAEQLAKLLGELDAPAFIVSMVVGLLVVGVAAPLTGTATIAAIGPVAFTTLMSAGVSPIPAAVAILIFASTEGASPPGAAPIYIASGISGVNPARTFVPLVVWYVLPILVIGSLVAIGALPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXC6</accession>
    <name>D3PXC6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016960.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1689"/>
    <dbReference type="EnsemblBacteria" id="ADD41389">
        <property type="protein sequence ID" value="ADD41389"/>
        <property type="gene ID" value="Snas_1689"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1689"/>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089574_6_0_11"/>
    <dbReference type="OMA" id="MLEFWVD"/>
    <dbReference type="OrthoDB" id="2056793at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="36"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="141" mass="14918" checksum="B851C59F8F0DBEED" modified="2010-04-20" version="1">MTPDAAPPGSQSIDDILAAARARLHRLDPAETHAAVRDGAVLVDIRPAAQRAANGEIPDAVIVERNVLEWRFDPRSDARLRVAGRYDLRVIVFCQEGYTSSLAAASLHDLGLHRATDLDGGFAAWRAAGLPTSDGPSAAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXC8</accession>
    <name>D3PXC8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epoxide hydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1691</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016962.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1691"/>
    <dbReference type="EnsemblBacteria" id="ADD41391">
        <property type="protein sequence ID" value="ADD41391"/>
        <property type="gene ID" value="Snas_1691"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1691"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_1_11"/>
    <dbReference type="OMA" id="IITWSMM"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033961">
        <property type="term" value="F:cis-stilbene-oxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EHN" evidence="4">
        <location>
            <begin position="4"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="377" mass="41686" checksum="711AF046BA6032A0" modified="2010-04-20" version="1">MSTEPFRIDVAETTLSDLRSRVANSRFTFATAPGWTKGADPAYLRDLTAYWAKDFDWRAAEARLNDHPQFLADVDGTRIHFVHVKAPRRDGAPEPLPLILSHGWPSSFVEMLPLVPLLSDRFDLVIPSLPGFGYSRLPDGALTRERIADLWHTLMTDVLGYSRFGAFGGDIGGGASQWLAAKYPDSVVGLHVIHPPAGGAGSTPSDGGPEPYTEAEQAFIDAEAAYDIEDQGYSEIMWTRPDTIGAALADSPVGLAAWIIDKYRDWSDCGGDVESRWDRDTLLTVITLYWVTESIGSSFRQYADYPHNRPRPTITVPVGVTLSHEPVMASFPRSLTERACTDLRHWSEPGRGGHFLAFEEPELMAAELRTFFATLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXD2</accession>
    <name>D3PXD2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1695"/>
    <dbReference type="ESTHER" id="stanl-d3pxd2">
        <property type="family name" value="HNLyase_Bact"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41395">
        <property type="protein sequence ID" value="ADD41395"/>
        <property type="gene ID" value="Snas_1695"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1695"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046066_3_0_11"/>
    <dbReference type="OMA" id="EMICADY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="20"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="292" mass="31590" checksum="8A34FA96C04D495F" modified="2010-04-20" version="1">MAATATGVALADDKRPKTYVFVHGTNSYSGFWTPYARELQYRGHRCIAVDQPYHGAGAYIPESYQSQDLEALATEPTPLGEIGLDDFAAHVEKSVRRAAKWGPVVLVGHSMGGASLSRVGDAVPELIAHLCYMAAYCCSTALPTIEECMTAPESETAILPEGVVIGDPEVLGVNRYNFLGASAEDLRMLKEMAWGDNSDASFRAGLLSMQPDESALVPAQRAVGGAEGWGGIRRTYLRFGADRLITPELQDRMIAEADDLTPDNRFRVHDFDAPHFGPEDVSDIVDVLAGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXH2</accession>
    <name>D3PXH2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017006.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1737"/>
    <dbReference type="EnsemblBacteria" id="ADD41435">
        <property type="protein sequence ID" value="ADD41435"/>
        <property type="gene ID" value="Snas_1737"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1737"/>
    <dbReference type="eggNOG" id="COG3087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051674_1_1_11"/>
    <dbReference type="OMA" id="MLRSPML"/>
    <dbReference type="OrthoDB" id="1828250at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="251" mass="26927" checksum="0F3E03DE5B23ED00" modified="2010-04-20" version="1">MLALIRSELVKARSTRATAWTLPLTIVLTGGLGALLGAAWRNSDLVKDDTAMRFAAFYPLTLSQMCLVVFAVLLVGNEFSTGTIRTSLIAVPGRVRFLTAKFIAGGLILTGVAVLAVAVSQVMTRLTLGDYAPPLDDKTLWLAILGACLYLPMIGLFAMGLTATLRSSIGALGILMPLLFLNSQGFGNIPKVKELAQYLPDQVGQSLMRMFPDNDPIFSVDYNVTGAAFILLAWVATALLGGYLVTRRREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXJ0</accession>
    <name>D3PXJ0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flavodoxin_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3662</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018891.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3662"/>
    <dbReference type="EnsemblBacteria" id="ADD43320">
        <property type="protein sequence ID" value="ADD43320"/>
        <property type="gene ID" value="Snas_3662"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3662"/>
    <dbReference type="eggNOG" id="COG4635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094839_1_0_11"/>
    <dbReference type="OMA" id="VAYATRY"/>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026816">
        <property type="entry name" value="Flavodoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12724">
        <property type="entry name" value="Flavodoxin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin_5" evidence="2">
        <location>
            <begin position="6"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="140" mass="15881" checksum="FA329E97D199C92F" modified="2010-04-20" version="1">MARGFTVETKDVEAVTSLTGFDVVVVGSAVYYGRWRRQANRFVKRFSSDLKQRRVRIFESGWVGQRPARVEPTRTAKKWAERFGAGPVAVFGGRLDPELAKTYLDRALTRRMASDSRDWPRVRDWAGKIADEVKTAADGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXK1</accession>
    <name>D3PXK1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3674</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018902.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3674"/>
    <dbReference type="EnsemblBacteria" id="ADD43331">
        <property type="protein sequence ID" value="ADD43331"/>
        <property type="gene ID" value="Snas_3674"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3674"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="SENDVAH"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="17"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="103"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="170" mass="19346" checksum="3F03F680306F5DCF" modified="2010-04-20" version="1">MDRQRSDFEEFAIACTPALLRSAYLLTGDRHLAEDLVQSALARTHRAWKRVGRDGNPQAYTRKTMYHLQVSWWRRRKVPESLTDIPVERPVADATGEVDLKVSLRAALFQLSRRHRAVVVLRYFEDRSVAQTAEILGRSEGTVKTQTLRALSKLRSVLPTPFELTNGATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXY6</accession>
    <name>D3PXY6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5685</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EfeM/EfeO family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020886.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5685"/>
    <dbReference type="EnsemblBacteria" id="ADD45315">
        <property type="protein sequence ID" value="ADD45315"/>
        <property type="gene ID" value="Snas_5685"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5685"/>
    <dbReference type="eggNOG" id="COG2822">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050342_2_1_11"/>
    <dbReference type="OMA" id="WTGWHRL"/>
    <dbReference type="OrthoDB" id="1430947at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd14656">
        <property type="entry name" value="Imelysin-like_EfeO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028096">
        <property type="entry name" value="EfeO_Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018976">
        <property type="entry name" value="Imelysin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034981">
        <property type="entry name" value="Imelysin-like_EfeO/Algp7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038352">
        <property type="entry name" value="Imelysin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13473">
        <property type="entry name" value="Cupredoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09375">
        <property type="entry name" value="Peptidase_M75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048687" evidence="3">
        <location>
            <begin position="23"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Cupredoxin_1" evidence="5">
        <location>
            <begin position="12"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M75" evidence="4">
        <location>
            <begin position="136"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="376" mass="41002" checksum="A9B96E2061A6473F" modified="2010-04-20" version="1">MRKPVFAVAVAALALTATAACAEKAKESDDGPIAVTATDDSCEVASTKAKAGTVTFKVKNDGKKVTEFYVYAKGDRVMSEVENITPGNTRELIVELPAGKYETACKPGMVGDGIRGKFTVTGKAEKLTEDENLADAVKSYKRYVAKQSEALVDKTGEFVDAVKDEDIDKAKELFPISRTYWERIEPVAEIFGDLDPRVDAREDDFPKGPKDPEFGGFHKLEYDLWITKDVSKSGKVADQLLKDVKEVVDRAEKEELTPLHLANGAKELLDEVATSKITGEEDRYSHTDLWDFAANLAGSEAAVASLRPVIDEKDPKLGKKLDEKFAAAEEALGEHAKGDGWRLWDELSKSELKELSDAINALGEPVSEVAGVVSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY41</accession>
    <name>D3PY41_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MMPL domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_5740</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020941.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5740"/>
    <dbReference type="EnsemblBacteria" id="ADD45370">
        <property type="protein sequence ID" value="ADD45370"/>
        <property type="gene ID" value="Snas_5740"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5740"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005108_1_1_11"/>
    <dbReference type="OMA" id="TWYMPRW"/>
    <dbReference type="OrthoDB" id="149255at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048076" evidence="7">
        <location>
            <begin position="47"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="525"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="556"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="593"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="635"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="669"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="8">
        <location>
            <begin position="200"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="903" mass="94696" checksum="526C9B15552150C2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYN7</accession>
    <name>D3PYN7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3814"/>
    <dbReference type="EnsemblBacteria" id="ADD43470">
        <property type="protein sequence ID" value="ADD43470"/>
        <property type="gene ID" value="Snas_3814"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3814"/>
    <dbReference type="eggNOG" id="COG0666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000134_18_13_11"/>
    <dbReference type="OMA" id="WTAMQEA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="173" mass="18488" checksum="2730C68C08461E80" modified="2010-04-20" version="1">MSSEEQAELDERLFTAVNDDDVDAAKALVKQGANVNALDDRHDTPWLVTGVTGSVDMLEALLPGEPDVTIRNRFGGTSLIPACERGHADYVAAVLERTDVDVDHVNDLGWTGLLEAVVLGDGSDPYQEIVASLIYHDADVNLADADGVTPLAHARQRGQDTVAKLLTEAGARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYQ4</accession>
    <name>D3PYQ4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019058.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3831"/>
    <dbReference type="EnsemblBacteria" id="ADD43487">
        <property type="protein sequence ID" value="ADD43487"/>
        <property type="gene ID" value="Snas_3831"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3831"/>
    <dbReference type="eggNOG" id="COG3375">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061573_0_0_11"/>
    <dbReference type="OrthoDB" id="1865059at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038764">
        <property type="entry name" value="GNAT_N_AcTrfase_prd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41700">
        <property type="entry name" value="PTHR41700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="223" mass="24564" checksum="A06B028470B5B28D" modified="2010-04-20" version="1">MSRSPDISLASTMDEHEELAALFARIWQVPEPSQIYPASLLRAVEFAGNYVAVAKLDGRIVGGAVAFFGRGGHLHSDIAGVDASVRGRGIGLALKLHQRSWALERGVRSIQWTFDPTLFRNARLNIHRLGGYAVAYLPDFYGRMDDGINADTGPSDRLLVDWRIDTPRVRGAITEGLAEPTDGLRVPIGPLDRLRADLTKAFDDGMRITDVTVDNHYIMERPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYT6</accession>
    <name>D3PYT6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LigA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43519">
        <property type="protein sequence ID" value="ADD43519"/>
        <property type="gene ID" value="Snas_3864"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3864"/>
    <dbReference type="HOGENOM" id="CLU_943047_0_0_11"/>
    <dbReference type="OMA" id="CEESQRM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="295" mass="33069" checksum="288AF2175F7BFB59" modified="2010-04-20" version="1">MGGFAVAQTGEPATRGRLQDPGRGQRRGPARRRRRRHHALLRQPRPGPGLRGRAAGRALRRRGSRRRAAGESRGDARHRGGGRSRAGRETGGDRADAGRRAETDAHPALRPPRRHRRSGNRRRRDPRGHDRCGHDPGAGGRRWARLGRRGRRQGAVTVHEGHRRRTGTGRRRRRQSAGRKAGVVADRGPVPHHRRRRARRTVRFDLRAPQGVRGRHRHRLRGRDRCRRGHRGPRGAPGGRAVRSPDRGGVPAPRRRLRTDGRGDQRRQPGAVAAGPAGRRRRVISTRPYRAASNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYV6</accession>
    <name>D3PYV6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3884</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019110.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3884"/>
    <dbReference type="EnsemblBacteria" id="ADD43539">
        <property type="protein sequence ID" value="ADD43539"/>
        <property type="gene ID" value="Snas_3884"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3884"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="LWHANSY"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="990" mass="108159" checksum="46598DC387CA2B67" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ61</accession>
    <name>D3PZ61_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021061.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5861"/>
    <dbReference type="EnsemblBacteria" id="ADD45490">
        <property type="protein sequence ID" value="ADD45490"/>
        <property type="gene ID" value="Snas_5861"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5861"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_2_2_11"/>
    <dbReference type="OMA" id="VVFAWQD"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041347">
        <property type="entry name" value="MftR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17754">
        <property type="entry name" value="TetR_C_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="197" mass="21972" checksum="5A947E7619F193EC" modified="2010-04-20" version="1">MTEERPVRGLRERTRLAVRAELSRLAVELFVRQGFERTTVDDITAAAGLSKRSFFRYFPAKEDAIFGDLDLLGEEVRADLRDRPTGEAPWDSLHQVLRGWSERIHSAGAVAEKLDLIETTPALRARFQHKREQLRDEIAAELRDRQPGGLSDFDIDLLTGAAAAALDAVSREVVRGGDPGAREELIDRAFAALKPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ95</accession>
    <name>D3PZ95_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1873</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1873"/>
    <dbReference type="EnsemblBacteria" id="ADD41569">
        <property type="protein sequence ID" value="ADD41569"/>
        <property type="gene ID" value="Snas_1873"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1873"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_3_0_11"/>
    <dbReference type="OMA" id="PEIVSCF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="20"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="165" mass="18115" checksum="71903483400C1FC0" modified="2010-04-20" version="1">MPGISKKKLNNTFGERDALLDPVNLRLLAALHADPRISMTQLAKQVSMSAPAVTERVQRMQRTGIIVGFHMDVDPAALGMPVTALVRIKPGPAQLPKLIEAVQKMPQVTECHRITGEDCLFVKVHVPSIARLDETLDQFLLYGQTTTSIIQSTPVPPRPLPVTHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZM1</accession>
    <name>D3PZM1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <ecNumber evidence="6">1.17.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1999</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.17.1.2" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017266.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1999"/>
    <dbReference type="EnsemblBacteria" id="ADD41695">
        <property type="protein sequence ID" value="ADD41695"/>
        <property type="gene ID" value="Snas_1999"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1999"/>
    <dbReference type="eggNOG" id="COG0761">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027486_3_1_11"/>
    <dbReference type="OMA" id="NEMAQAD"/>
    <dbReference type="OrthoDB" id="1235756at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30426">
        <property type="entry name" value="PTHR30426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="407" mass="42932" checksum="E4F5111FCD92EBB6" modified="2010-04-20" version="1">MGRSIWVEWFTTSGVSTGEVVVLEEFRHPRRGRVRSPARALIAAWLRRRGLRVRRGKLPLYGDGAQGDSALLCVSYLDETHGAAGFAVAVPGEDAGLRAMVESMVMAWVSVLRTRRVLLAGGEPWCVGGRRVVELVESTLDDGAELVHVVGDLAASPERRVALRERGVVPVTALDEVPDGARVVVGAAGIPEEQRVKAAKRGVRIVDGTCPHIASGKAQVRRYAERGDAVVLVGQRGHASTEALSGQAPDATLVVETTADVEQMRGGDGVSAVPVPSMAIGAVVPMLAALRRRFPKLPVQHPDQWCYQTQDRLATVRELAGTADVVFVLGPPESPETVRLLDVAASNAVAVGGLGDIEPSYLVDVGSVGVVVGGDASEGLRGELLTALGGLGPVAVSELRVQTRTMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZT7</accession>
    <name>D3PZT7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent helicase HrpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3972</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3972"/>
    <dbReference type="EnsemblBacteria" id="ADD43624">
        <property type="protein sequence ID" value="ADD43624"/>
        <property type="gene ID" value="Snas_3972"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3972"/>
    <dbReference type="eggNOG" id="COG1643">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001832_5_6_11"/>
    <dbReference type="OMA" id="DLRILVM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010225">
        <property type="entry name" value="HrpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013689">
        <property type="entry name" value="RNA_helicase_ATP-dep_HrpB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08482">
        <property type="entry name" value="HrpB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005496">
        <property type="entry name" value="ATP_hel_hrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01970">
        <property type="entry name" value="DEAH_box_HrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="36"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="227"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="819"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="841" mass="90329" checksum="06DE175B0D2513BD" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZX0</accession>
    <name>D3PZX0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YggT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4005"/>
    <dbReference type="EnsemblBacteria" id="ADD43657">
        <property type="protein sequence ID" value="ADD43657"/>
        <property type="gene ID" value="Snas_4005"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4005"/>
    <dbReference type="eggNOG" id="COG0762">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136788_5_0_11"/>
    <dbReference type="OMA" id="QFARSWR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="YGGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="99" mass="11220" checksum="8BAC9B2B442F9BFD" modified="2010-04-20" version="1">MFDTIMQSLYLALYVFYLLLLARLVAGAVVRFSRRWEPNRGTAIALELIFSATDPPLKGLRRLIPPLRLGTVALDLAFIALLLIVFILKTYVVGSWLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZZ6</accession>
    <name>D3PZZ6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dual specificity protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021096.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5897"/>
    <dbReference type="EnsemblBacteria" id="ADD45525">
        <property type="protein sequence ID" value="ADD45525"/>
        <property type="gene ID" value="Snas_5897"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5897"/>
    <dbReference type="eggNOG" id="COG2453">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126482_0_0_11"/>
    <dbReference type="OMA" id="RWPDFRL"/>
    <dbReference type="OrthoDB" id="1972497at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="1">
        <location>
            <begin position="66"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="144" mass="15907" checksum="74837F1531A587FD" modified="2010-04-20" version="1">MSTSWDTAAKGVLRLPSGRLIRGRGLRYPLPTGPEPDFGLYLLGKPPPRPQWKHRWLRWPDFRLPGDRAEAAEAFAEVLERTGTERVEVACGGGKGRTGTALACVAILDGVPPAEAVAYVRQHYAKGAVETPWQRRYVRRFAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0B6</accession>
    <name>D3Q0B6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015351.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0058"/>
    <dbReference type="EnsemblBacteria" id="ADD39780">
        <property type="protein sequence ID" value="ADD39780"/>
        <property type="gene ID" value="Snas_0058"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0058"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_4_1_11"/>
    <dbReference type="OMA" id="VIREYHT"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="216" mass="23845" checksum="21EC4459A6ABC567" modified="2010-04-20" version="1">MECESRTDGRLERGNAKRRAILDRAVDLASISGLDGLSIGKLAAELGISKSGALLHFGSKLELQLDVITHAAERFGRAVIAPAAEQPVGLPRLWYLTDGWLHHIEIETFPGGCFFSTVGAEFNSRPGRIHDALAKIHNRWSNLLEQQAVAAREAGQLRPDVVAERLVFELDALIRHANMHRQLHDSRKVLGHAREAVRDLLTRVGTEAAVRELFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0H1</accession>
    <name>D3Q0H1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2012</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017278.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2012"/>
    <dbReference type="EnsemblBacteria" id="ADD41707">
        <property type="protein sequence ID" value="ADD41707"/>
        <property type="gene ID" value="Snas_2012"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2012"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="IVQACEF"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="5">
        <location>
            <begin position="4"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="327"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="342" mass="36048" checksum="13ADF139F4DFB93F" modified="2010-04-20" version="1">MGRPTIADIAAAAGVSKSAVSFALNGRPGVSDETRAAVLKIAEELDWMPHSAARALSGSRSHSIGLALARPARTLGVEPFFTQLLSGIQAKLSERSIALQLLIVEDAEAEIATYRRWAGEHRVDGLVLVDPQTRDRRIAAVEALSVPAVVVGGNGRSGTLASVWADDRAAMLSIVDYLVALGHKRLAHVSGMPGLQHTRRRAKALKDTVASHKLLSADSLSTDFSDAEGAAATRRLLSGRARPSAIVYDNDVMAVAGLGVATEMGVTVPGELSIVSFEDSRLTQLTHPAITSLSRDTYAFGEKVAETLLAVIDDPAAAVGHKMPTPSLTVRESTARPLDNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0N0</accession>
    <name>D3Q0N0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Agmatine deiminase</fullName>
            <ecNumber evidence="2">3.5.3.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.3.12" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017337.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2072"/>
    <dbReference type="EnsemblBacteria" id="ADD41766">
        <property type="protein sequence ID" value="ADD41766"/>
        <property type="gene ID" value="Snas_2072"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2072"/>
    <dbReference type="eggNOG" id="COG2957">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037682_0_0_11"/>
    <dbReference type="OMA" id="WESHARS"/>
    <dbReference type="OrthoDB" id="771174at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047632">
        <property type="term" value="F:agmatine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004668">
        <property type="term" value="F:protein-arginine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009446">
        <property type="term" value="P:putrescine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007466">
        <property type="entry name" value="Peptidyl-Arg-deiminase_porph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31377">
        <property type="entry name" value="PTHR31377"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04371">
        <property type="entry name" value="PAD_porph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="364" mass="39096" checksum="0AF5CC1026CC2618" modified="2010-04-20" version="1">MRMSRRDGLRAAMAAAAGGALSGCGGDDGGPTEKWRMPDEAHPHELTYMSWPTEKIWGPYIDDVRDDIAGIARAIAEFEPVVLLANASDVKAASKACGSEVDVIPIPVDDLWTRDTGPNLVLGKGGIAGVDLNFNGWGDKQSNKRDREVAREILAEADIERIKAPIVGEGGSIEVDGKGTLLATESSLVNDNRNPGKSRDDIEAALKRLFGVTTVIWVKGVKGEDITDYHIDALARFSEPGVVVMSVPDEEAPEDVWTRAYDQARAVLDEAVDARGKRLEIVELPEPFDIGDRGENFLASYVNYYVVNDGVVIPRFGDKRADADAKSIVADLYPGREVVQVSVDGLGEGGGGIHCATQQLPKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q160</accession>
    <name>D3Q160_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mannose-1-phosphate guanylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6015"/>
    <dbReference type="EnsemblBacteria" id="ADD45640">
        <property type="protein sequence ID" value="ADD45640"/>
        <property type="gene ID" value="Snas_6015"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6015"/>
    <dbReference type="eggNOG" id="COG0836">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035527_0_1_11"/>
    <dbReference type="OMA" id="LIVCNEK"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005976">
        <property type="term" value="P:polysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001538">
        <property type="entry name" value="Man6P_isomerase-2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01050">
        <property type="entry name" value="MannoseP_isomer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="67"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="MannoseP_isomer" evidence="2">
        <location>
            <begin position="384"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="425" mass="45461" checksum="8F94F8416E13563B" modified="2010-04-20" version="1">MASVLLRRPLTRRLAALSPDPKYTRYEGPAPPCQAWSGAVSRRTSHYRPLSLPLLSLGILCRMLHSVIPAGGSGTRLWPLSRADNPKFLHPLTGSDLTLIQSTVARLAPLSDAAHRYVVTGTAHAAAVARQLPELPESNILVEPSPRDSAAAIALAAAVIAERDPNALMGSFAADHLIADAAGFAKTVEAAMEMAADGLLMTIGITPTGPDTSYGYLRRGEALGAGNLLQEFKEKPDHVAAVEYVSSGDYLWNASMFVWRVDVFLAELNRQRPHLHDTVRELAGAWDSPRREELFGKLWPELEKISVDYAVMEGAAAAGKVGVVPGDFGWNDVGDFDTLGAILPPHDDSGNVVISTGAEGVDVLTLDARRNVLVPGSGRLVATVGTDDLIIVDTPDALLVCPRDRAQDVKKLVDELKNRGDTGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1I4</accession>
    <name>D3Q1I4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015403.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0111"/>
    <dbReference type="EnsemblBacteria" id="ADD39832">
        <property type="protein sequence ID" value="ADD39832"/>
        <property type="gene ID" value="Snas_0111"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0111"/>
    <dbReference type="eggNOG" id="COG1262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012431_4_2_11"/>
    <dbReference type="OMA" id="YEWTADC"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="2">
        <location>
            <begin position="42"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="319" mass="34784" checksum="01F93490D6F7710E" modified="2010-04-20" version="1">MAMDSCCAPARDPENPDPAAGDGADAWGFAVPKREPAKVRRGMVRVDVGEFDMGGEDVDANPTDGEGPPRPVRLSPFHIDTVCVTNVEYARFVRETGFVTDAEREGWSYVFHLLVAPTARGHVMDASVPGAPWWLAVRGASWRAPHGPGSSMSSVQNHPVTHVSWRDAAAYAAWAGKRLPTEAQWEAAARGGLSGARYPWGDELLVRGAHRCNIWQGSFPRHNTAEDGHLGTAPVKTFRPNGYGLYQMAGNVWEWCADWWTTARDGDSDPTGPATGTSKVIRGGSYLCHDSYCNRYRVAARTHNTPDSSTGHMGFRCVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1L1</accession>
    <name>D3Q1L1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015430.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0138"/>
    <dbReference type="EnsemblBacteria" id="ADD39859">
        <property type="protein sequence ID" value="ADD39859"/>
        <property type="gene ID" value="Snas_0138"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0138"/>
    <dbReference type="HOGENOM" id="CLU_2095368_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="116" mass="12165" checksum="6D358FAC72C45C75" modified="2010-04-20" version="1">MHSLTRRLATVTLGGALLVGSLTGCGIFGTAVDCGKLAAATNDVTSNMTDADGLKSAIEKFRAAAKDIDDAELKDSVNTFADEAEKFQKYIDNPTGDVPDESKMMEAATDIEAKCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1M0</accession>
    <name>D3Q1M0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UbiA prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0148</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0148"/>
    <dbReference type="EnsemblBacteria" id="ADD39868">
        <property type="protein sequence ID" value="ADD39868"/>
        <property type="gene ID" value="Snas_0148"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0148"/>
    <dbReference type="eggNOG" id="COG0382">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080174_0_0_11"/>
    <dbReference type="OMA" id="LLYDWPL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD39868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="258" mass="26041" checksum="A1932E2DEC323274" modified="2010-04-20" version="1">MKPPALIRACHPGPSMTVTLVGAGLAAASGRDAVSVASVFVAVLLGQLSIGWSNDALDAARDTETGRPDKPVAAGEVSRRLLFWLAGAAVVGSAAASLYVGWQGSLHILAVASAWSYNHPLKRTPLSVLPFAVSFGLLVGYADADPRPGMIAAGALLGAAAHFANVLPDLDDDARTGVRGLPHRLGARGSQLVAATLLAASGVIAGLHIVNVAGIAVMALSAVFAIVVLVSRPGRTVFRVVMAAAIVDVVALLAAVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1P7</accession>
    <name>D3Q1P7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015466.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0175"/>
    <dbReference type="EnsemblBacteria" id="ADD39895">
        <property type="protein sequence ID" value="ADD39895"/>
        <property type="gene ID" value="Snas_0175"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0175"/>
    <dbReference type="eggNOG" id="ENOG50333SK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1271661_0_0_11"/>
    <dbReference type="OMA" id="FYAANGW"/>
    <dbReference type="OrthoDB" id="1762270at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="231" mass="23871" checksum="F5B692EEB0EE904F" modified="2010-04-20" version="1">MSAISKSDRITTGLAGLLSGVLSILMVGLYFVYDGAPPPENVLGRNLITVTTFIGFLIFGAGLARLLRQARGGDAGLSGSIAVTSLLTYVAVTLVSASLEVGTSLWKPNSDMDPTVDGPLAAGMVLLHGPIARGLVAAFLITLTISAARTGLLRRWVLTGNIILALTNLALVPSLFFGMNAANFYAANGWGAVASIGLINVIWFATLGGALLRSRAARQTPVPTPAPAPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1Q0</accession>
    <name>D3Q1Q0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0178</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0178"/>
    <dbReference type="EnsemblBacteria" id="ADD39898">
        <property type="protein sequence ID" value="ADD39898"/>
        <property type="gene ID" value="Snas_0178"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0178"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="PVCDGIT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="153"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD39898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="23393" checksum="F602C27D29F1CB58" modified="2010-04-20" version="1">MDVTTTSVLLVDDDPMVRNGLRMVLRADPGIVVVGEAGNGRQAVDQARELRPDVVLMDLQMPVMDGVAATRELRGLPDAPAVLVLTTFHLDTYILDALGAGASGYLLKDIPPTEIARAVQMAAAGESVFSSSVTRSLVQRVASPATDPKIEAARAALAALTEREREVAAAVAAGKSNAAIASEMFMSEATVKTHVSRILTKTRSQNRVQIALTVYRASGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q224</accession>
    <name>D3Q224_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Uridylate kinase</fullName>
            <shortName evidence="6">UK</shortName>
            <ecNumber evidence="6">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Uridine monophosphate kinase</fullName>
            <shortName evidence="6">UMP kinase</shortName>
            <shortName evidence="6">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pyrH</name>
        <name evidence="8" type="ordered locus">Snas_2200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017462.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2200"/>
    <dbReference type="EnsemblBacteria" id="ADD41891">
        <property type="protein sequence ID" value="ADD41891"/>
        <property type="gene ID" value="Snas_2200"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2200"/>
    <dbReference type="eggNOG" id="COG0528">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033861_0_0_11"/>
    <dbReference type="OMA" id="PIIVFDM"/>
    <dbReference type="OrthoDB" id="1043239at2"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04254">
        <property type="entry name" value="AAK_UMPK-PyrH-Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_B">
        <property type="entry name" value="PyrH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015963">
        <property type="entry name" value="Uridylate_kinase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02075">
        <property type="entry name" value="pyrH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="7">
        <location>
            <begin position="11"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="15"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="137"/>
            <end position="144"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="244" mass="26282" checksum="3D136692AC1D28DB" modified="2010-04-20" version="1">MADAERRPYRRVVLKLSGEVFGGGAVGVDPDVVAGIAAQITKASKSGVQVAVVVGGGNFFRGAELQRRGMERSRADYMGMLGTVMNCLALQDFLEKEDVETRVQTAITMAQVAEAYIPRKAMRHLEKGRVVIFGAGAGLPYFTTDTVSAQRALEIKADAVLMSKSGVDAVYTADPRIDPNAERLETITFDEVLQRRLQVADQAAFSLCQDNDLPIVVFGAEVEDGISRALCGERIGTLITSARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q250</accession>
    <name>D3Q250_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2227"/>
    <dbReference type="EnsemblBacteria" id="ADD41917">
        <property type="protein sequence ID" value="ADD41917"/>
        <property type="gene ID" value="Snas_2227"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2227"/>
    <dbReference type="eggNOG" id="COG1725">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_10_1_11"/>
    <dbReference type="OMA" id="MVEFRID"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="129" mass="14349" checksum="C4F4B7E1B8B65CE2" modified="2010-04-20" version="1">MIRFRIDRRAGVASYMQLVQQVKHAMRVGRLGPGDKLPTAKEVVADTAINPNTVFKAYRVLEGEGLVEGRPGVGTFVRESLARPETPDTSRLRDELAQWTDRARAAGLGREDIEAVVRTVLDDSYPKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q292</accession>
    <name>D3Q292_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4174</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019396.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4174"/>
    <dbReference type="EnsemblBacteria" id="ADD43825">
        <property type="protein sequence ID" value="ADD43825"/>
        <property type="gene ID" value="Snas_4174"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4174"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_13_2_11"/>
    <dbReference type="OMA" id="WINSSRW"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="383"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="218"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="414" mass="44151" checksum="256788A7EDCEF481" modified="2010-04-20" version="1">MTETPTGLLRRNRDFRNVWAADALSTVGTRLSMLALPLLALLTLDATPLEVALLRTLETLAWLVLGLVAGAWMDRIRCRGVLIAADLGRAAVLASIPIAYLAGVLTLTQLFVVSLLAGIGKVFFGVAATTYLPRLLPKEDLVDANAKLATNLSMAAVLTSGGGGFVIQWLTAPIAIAVDAASFVWSALWLRGIRKVETVPRQDNPPHLRRDIAEGWRFVVGHPLLRALAGLSVCTVFFQAVHDAVWITFLVREFGLSAGVIGLLGMSGLLGAVLSGFVTSRIARRLGNVRAAVAAAVCFAVGFALFPFTLPGWGLSVAVVAGFMVSFSIITLSVMRSSIRQLLCPEHLYGRVGATMEFMIWGTMPLGSLAGGLIATVTDLRTTLWIVGAGTLLSLLWIVLSPLRTTREIELAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2L1</accession>
    <name>D3Q2L1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021333.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6139"/>
    <dbReference type="EnsemblBacteria" id="ADD45762">
        <property type="protein sequence ID" value="ADD45762"/>
        <property type="gene ID" value="Snas_6139"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6139"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033540_1_0_11"/>
    <dbReference type="OMA" id="FNANAHR"/>
    <dbReference type="OrthoDB" id="1759737at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="428" mass="47615" checksum="F4E8F1CEB6BFEE4A" modified="2010-04-20" version="1">MPFDKSGDTALGFRVAMLRSQRGISRRVLANLVGRSEEWLRLIEIGRRPLDSLSIVLQIAEILHVSDVAAFIGTRPEVRRPEAQMTTRLSALRRVVTEVPWMRATAPLPVDDPGATLAALWERWRTSPTRYTEIAVGLPPLLAHFQDLSETEPGQPRWNTGLISCYVLARSVFNRTGEHDVARLAADRALRAASTSALDWMRPIAVWHLGCALLHIDQLRPALDCVDTAVDRMHEFPSHAADRAWLTGALHLLAAEIAAAQYDPATANTALGRAGRIADGMDEDRSQLGVWCGPTELGIVRIRVALQLGDIEQALRFARTLHIPHGYSAERVARHYVALAGAYASRHNDVAAVYALTKVEQVSPEDIYFNANAHRTLRLLADRNDLTVRSDLERLLNLVPAENVNGLTPQRRCDPGGYRESRHRFFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2T8</accession>
    <name>D3Q2T8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydropteroate synthase</fullName>
            <shortName evidence="1">DHPS</shortName>
            <ecNumber evidence="1">2.5.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dihydropteroate pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6218</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHPS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.15" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6218"/>
    <dbReference type="EnsemblBacteria" id="ADD45839">
        <property type="protein sequence ID" value="ADD45839"/>
        <property type="gene ID" value="Snas_6218"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6218"/>
    <dbReference type="eggNOG" id="COG0294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008023_0_1_11"/>
    <dbReference type="OMA" id="FSIDTYH"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00156"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="3">
        <location>
            <begin position="24"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="291" mass="30861" checksum="2A5BECC121B3FA91" modified="2010-04-20" version="1">MTGTDRPDNAGDHDSATDSGPDRPVIMGVLNVTPDSFSDGGRYTSVDTALAHARRMRRDGAEIIDVGGESTRPGAKRIDAATEIARTVDIVAALTADGMTVSIDTTRASVAEVAIRRGASIVNDVSGGLADPELAPLVARTGAKFVLMHWRGHSADMYAPASYDDVVTEVRAELLERVDAARKAGVAAEQIILDPGIGFAKLPEHNWTLLKHLDALVELGYPILYGSSLKSHLGQLLAGPDGEPRPVAERADATLATSLLAFSAGVWGVRVHDVRGTADARQVWEATRRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2U5</accession>
    <name>D3Q2U5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative adenylate/guanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the adenylyl cyclase class-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6225"/>
    <dbReference type="EnsemblBacteria" id="ADD45846">
        <property type="protein sequence ID" value="ADD45846"/>
        <property type="gene ID" value="Snas_6225"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6225"/>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_511811_0_0_11"/>
    <dbReference type="OMA" id="WHAQHIT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="16"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="532" mass="57416" checksum="7E0D1228D695CAF2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2V5</accession>
    <name>D3Q2V5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_6235</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021427.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45856">
        <property type="protein sequence ID" value="ADD45856"/>
        <property type="gene ID" value="Snas_6235"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6235"/>
    <dbReference type="eggNOG" id="ENOG502ZRCY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1694454_0_0_11"/>
    <dbReference type="OMA" id="HERQAYE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043760">
        <property type="entry name" value="DUF5706"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18967">
        <property type="entry name" value="DUF5706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="155" mass="16474" checksum="2634233032121828" modified="2010-04-20" version="1">MVSIAALRADELAAVRTELSRIDTKAGLLGTGVLAGLAWGAAALTPDKSLAVTVCGWGAEATAAAAGIVLLLVVRPRLRGRHGFLAWSGHPVTSWVRLERLAANDHDHQHERHAELTELAAMVKHKYRLLRLAVDMLLIAAALAAVTIIVDIVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q326</accession>
    <name>D3Q326_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015567.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0278"/>
    <dbReference type="EnsemblBacteria" id="ADD39996">
        <property type="protein sequence ID" value="ADD39996"/>
        <property type="gene ID" value="Snas_0278"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0278"/>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1239506_0_0_11"/>
    <dbReference type="OrthoDB" id="1930218at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="223" mass="25328" checksum="118A203A9F0F4A75" modified="2010-04-20" version="1">MDKQLARAIRVAVRHTQTPTEDELRTIEKLHVLRARDLSGLESCTSMRHLVLSGCDPVSLQSLTGMRDLEVATVEYCGLRRLDGVEELSDSFLYLKAPNNSIEDLSPLLDCPGLNRLEVQGNPLSEHSYLEILPRLRARGVQVFASGMREWRLTRRLHEIGLPFSYYHSDEGHQLCRPGLSYTDFPATGHPIIDPDDLERLIDAEPTRIHELFAQEELMFALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3I4</accession>
    <name>D3Q3I4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017596.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2339"/>
    <dbReference type="EnsemblBacteria" id="ADD42025">
        <property type="protein sequence ID" value="ADD42025"/>
        <property type="gene ID" value="Snas_2339"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2339"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_18_6_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="151" mass="16719" checksum="B67FE98BAD07A0D5" modified="2010-04-20" version="1">MTPDANRLAQQLQAMQTGLTPQILRGTGQDELQLIDVALLSALTDGRELTVKGLAATIGRSVSRTSRLIDRLVCRELLERREHPTDRRARYIKLSPAGAAFMSSFRTARAEQIARILDHLSPQEQTIVSEALDLIAKAARKSREEPDSGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3T1</accession>
    <name>D3Q3T1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Death-on-curing family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019569.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4351"/>
    <dbReference type="EnsemblBacteria" id="ADD43998">
        <property type="protein sequence ID" value="ADD43998"/>
        <property type="gene ID" value="Snas_4351"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4351"/>
    <dbReference type="eggNOG" id="COG3654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115697_5_1_11"/>
    <dbReference type="OMA" id="YDTLWLK"/>
    <dbReference type="OrthoDB" id="1838027at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006440">
        <property type="entry name" value="Doc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39426">
        <property type="entry name" value="PTHR39426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01550">
        <property type="entry name" value="DOC_P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="1">
        <location>
            <begin position="6"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="129" mass="14390" checksum="178D7DCD0B9F01BE" modified="2010-04-20" version="1">MTKYLDIRDLTHIASRLLDCDEPPVRDWGMLESAAMRPRATVFGTEAYPALHDKVAALIHSIARNRALVDGNKRLAFMAGYMMYGLNGYDLIPPSVDEGEAFIVGIARGDLEVPEIAATQSRWVRRQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q414</accession>
    <name>D3Q414_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Beta-glucosidase</fullName>
            <ecNumber evidence="3 11">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Snas_6279</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3 11"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021470.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6279"/>
    <dbReference type="CAZy" id="GH1">
        <property type="family name" value="Glycoside Hydrolase Family 1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45899">
        <property type="protein sequence ID" value="ADD45899"/>
        <property type="gene ID" value="Snas_6279"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6279"/>
    <dbReference type="eggNOG" id="COG2723">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001859_1_3_11"/>
    <dbReference type="OMA" id="VEACDRK"/>
    <dbReference type="OrthoDB" id="654705at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018120">
        <property type="entry name" value="Glyco_hydro_1_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017736">
        <property type="entry name" value="Glyco_hydro_1_beta-glucosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="Glyco_hydro_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="PTHR10353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03356">
        <property type="entry name" value="BGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00572">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6 11 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="426"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 10">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD45899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="463" mass="50616" checksum="053247575E7C7075" modified="2010-04-20" version="1">MTRNGNGFGPDFTWGAASSAYQVEGAATADGRGPSIWDTFAAAPGRVVDASTGETAVEAYHRVDEDVAVMRELGLRAYRFSVSWPRVVPDGTGAVNQAGLDYYRRLTDRLLDAGIEPWVTLYHWDLPQPLEDAGGWPERDTALRFADYALTVHEALSDRVDNWITVNEPWCAAFLGYASGEHAPGRREPAAAIAAAHHLLLGHGLATTGMRSADASSRIAIGLNFYPVHPASDRPDDVDAARRVDGVQNRLFTEAVLRGAYPSDVLADFKPVRDPDYIHDGDLRIISTPIDRLCVNYYSRFTVTGTANGRASASAAPTDTGSAWPGNEHIGFVGADLPVTGMGWEIDPDGLRDQLLRLAREYPGVELVVTENGAAFDDVLSDDGTAVHDQRRLVYLRRHVAACAEAIAAGVPLSGYFVWSLMDNFEWAWGYTKRFGVVYVDFETQRRVVKDSGHWYRDLIAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q488</accession>
    <name>D3Q488_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6357"/>
    <dbReference type="EnsemblBacteria" id="ADD45973">
        <property type="protein sequence ID" value="ADD45973"/>
        <property type="gene ID" value="Snas_6357"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6357"/>
    <dbReference type="HOGENOM" id="CLU_908848_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="362" mass="39901" checksum="8A48ED1A999D0908" modified="2010-04-20" version="1">MACMTEGSQEQAETDDAPIPAPKRRWPVVAGVVVMLLVLCLVAYLGGWFASKPDPGGSQPSAEVSAEDMEIDFDLKSAAFYLPPDNRPYYLYGDKYRFDLDDREPAVEPVRFTDGLYYPTEGDSGDEPHMRLAEGTKPIFTDVNGDSNTDVVATLEFTGTPEKRYTAWKGVFIWLWNDGKVVPVKHPAAWQWMDCPGESDLTVKRDGLSGLPLVTRSGDGNCDGEKNDSQGENPPPQTVFVQDGVPVSIGHATSAVDRCYFFDMYKKDANYVVTKEVPVRLAPDPDAAEIDGTVLVPGEGGKVTDTGEKQTIDRIELRIGKKPDKKLYDGWIPANLVWSGANEPISCGWVNWDDIGKKLKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4E2</accession>
    <name>D3Q4E2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0385"/>
    <dbReference type="EnsemblBacteria" id="ADD40102">
        <property type="protein sequence ID" value="ADD40102"/>
        <property type="gene ID" value="Snas_0385"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0385"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_28_0_11"/>
    <dbReference type="OMA" id="CGCFMQN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="35"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="219" mass="23955" checksum="CD4178D8E7E14C8B" modified="2010-04-20" version="1">MRRFTPGTPSIALRNRIGQLDPKPGSLAGMARPRQFDEDRAIDIAMRVFWAKGYAATSTDDLCEATGLKRSSLYNTFTSKHRLFTLALTRYMDTKTTALLETLDADTPIRERLRTVLRTAVDDELTGSDGCLVVNSIMELARTDRDVARLLSADADRRTAALRTVIHAGQRTGELDPDRDPLALANFVTATVGGLRVSARSGATPQTLESIMETAISAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4G2</accession>
    <name>D3Q4G2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015693.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0405"/>
    <dbReference type="EnsemblBacteria" id="ADD40122">
        <property type="protein sequence ID" value="ADD40122"/>
        <property type="gene ID" value="Snas_0405"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0405"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_11_6_11"/>
    <dbReference type="OMA" id="RAYYTEV"/>
    <dbReference type="OrthoDB" id="1823496at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="165" mass="18201" checksum="4999A603566DEBD6" modified="2010-04-20" version="1">MPNWTIKPEPIGAPDVDDVMEQYFDEMGRRVLGREATETEKRAALTADPNDKLAPPRGLFLVARDPDGEFLGCAGVRLLPADPRTAELKRMFVHPAGRGAGLGRGLLLAVEDAARTLGAKRIVCETNTKLTEARTLYTRNGYAETEPYEGHGKADHWFAKDLDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4G3</accession>
    <name>D3Q4G3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Secretion protein snm4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0406</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EccD/Snm4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015694.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0406"/>
    <dbReference type="EnsemblBacteria" id="ADD40123">
        <property type="protein sequence ID" value="ADD40123"/>
        <property type="gene ID" value="Snas_0406"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0406"/>
    <dbReference type="eggNOG" id="ENOG502ZAY5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028325_1_0_11"/>
    <dbReference type="OMA" id="HEQRPTI"/>
    <dbReference type="OrthoDB" id="1786282at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044049">
        <property type="entry name" value="EccD_transm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006707">
        <property type="entry name" value="T7SS_EccD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024962">
        <property type="entry name" value="YukD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19053">
        <property type="entry name" value="EccD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08817">
        <property type="entry name" value="YukD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017804">
        <property type="entry name" value="Secretion_EccD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03920">
        <property type="entry name" value="T7SS_EccD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="EccD" evidence="5">
        <location>
            <begin position="99"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="465" mass="48117" checksum="725F8FEDAE1CA667" modified="2010-04-20" version="1">MALTNQLCRVTVVAPNTRMDIALPDHVRLCDLQSDLLSHAAEGPGGDDLLDDGADAGGWVLTRLGGAPLDPQLTPRQHDIVDGEELYLVPVTDTGPQAVFDDIIDAMATANQKRERKWRTGSSRRFGIGFAIAAILGSAVACVASGTTVAMWTATALCATALLAALIFARALGRVTEAAVMGLLACGYALAAGVLALAPLATIADVSAPRLMVGGAAVAVIAVASGIGVPTAAPIFSATAICGTALAGAAALCAFVDAAPAQAGSVAAAVVLGLIPAMPMLAFRVARLPMPTIPRSPQQLRADTNIVDSQMALRRSERADEHLSGLLTATAIISGTATVYLALHGTLAAILLASLLTVLAFMRARIFPTVRQRLPFLLAATAGLAGLALSAWVHWPPEYRFVLLVAGLVATAAIALGYVLGVAGKPIAPTWGRLVDILEVILFVAVVPLTLWVWDAYWWVRTVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4L2</accession>
    <name>D3Q4L2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0457</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015743.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40172">
        <property type="protein sequence ID" value="ADD40172"/>
        <property type="gene ID" value="Snas_0457"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0457"/>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_17_1_11"/>
    <dbReference type="OMA" id="GSWYFHC"/>
    <dbReference type="OrthoDB" id="785253at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="6">
        <location>
            <begin position="84"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="5">
        <location>
            <begin position="211"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="422"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="463"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="487" mass="54964" checksum="C041C49B4EDA01F1" modified="2010-04-20" version="1">MAGKGVIFKRCGCRNSTTGKRLLSECPRLSERGHGSWYFHCSVVDLWGRHHRIRRGGFASRAAATTARDTVVEQSAAQATGSTWTVTRWLRFWLAHRQTIRPTTARSYQLHIDLVGPYLDKVSLAGLTCQHLTEMFAELAARPNRHGRPCAAGTWQRVRATLRAALNGAIREGLIDRNAARHVELANPHRPHAVVWTADRVEAWRRTGIRPAVAVWTAAQLVRFLDCVQGDREYVLWSLIAFRGMRRGEAAGLRWMDVDLDRRQLMVTQQLATLGRAIYTCPPKSRSSRRIVALDRHTVALLREHAERQRREQRAAGYAWHETGYVFTRPDGRPHHPDYLTSRFRILCDRHDLPPIRLHDLRHGAASLAHTAGADLKTVQEQLGHGSIVLTADTYTSVLPQTHHAAAAATARLILDTARATGRRLRQPASRREPKVKAEPCSVAAGPVDSDIAKTPSGIKRDKRHGNSKRKRRQRRGNHRPHKKRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Q4</accession>
    <name>D3Q4Q4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017655.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2401"/>
    <dbReference type="EnsemblBacteria" id="ADD42084">
        <property type="protein sequence ID" value="ADD42084"/>
        <property type="gene ID" value="Snas_2401"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2401"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_8_4_11"/>
    <dbReference type="OMA" id="YKPETAM"/>
    <dbReference type="OrthoDB" id="1616572at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA" evidence="1">
        <location>
            <begin position="8"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="31281" checksum="C57836EDE8D5BDB3" modified="2010-04-20" version="1">MSKQDKTILVTGATGKQGGVTARALLADGWRVRALVRDAKARTAGALAEAGASLVTGDFDDPASLAAASAGAYGLFAVPPAVYEPQGWNVELETRRGADLVDAATAAGVEHIVFTGIATATGAGLTGSSGKQRIEEHIKATGRRYTLLRPVRFMENYLFRESPVDGIRHGVHRHLFHPDRPMQIIAVADVGAIAALAFADPDTYGGKALELAGDAPTPVAAVKAISAALGREIRYEQFTAAEAERLGPEIADIRTLWTEGNGWNADIPAIRELHPGLLDFEGWLAAGGAERIKAAISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4R5</accession>
    <name>D3Q4R5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017666.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2412"/>
    <dbReference type="EnsemblBacteria" id="ADD42095">
        <property type="protein sequence ID" value="ADD42095"/>
        <property type="gene ID" value="Snas_2412"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2412"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1057308_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="94"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="263" mass="28375" checksum="C4BA7F864A33307F" modified="2010-04-20" version="1">MATGPSWNEGDLDGLTEPELERLGGKAWREGDYALAEREYQLAVVRAATPAAKARALNNLGTTYDRMGHGDKALASFTRAVDVYRAVGERHGEAEALTNLGLALGKQGQRDQATTHLSDALRLHLDNGDRFGQATVLSIMAELDRANGDLDAALATHRQALEIYCELSRADAESTCLNDCATTLLAMNQVQAALTAYANALALAQLVGADGERARAHDGIARILFSQGDRTGARTHWSSAWRLFQDSDKDSAEAVAVRLRQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4Y1</accession>
    <name>D3Q4Y1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2478"/>
    <dbReference type="EnsemblBacteria" id="ADD42161">
        <property type="protein sequence ID" value="ADD42161"/>
        <property type="gene ID" value="Snas_2478"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2478"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_3_5_11"/>
    <dbReference type="OMA" id="DGCFPEH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="273" mass="29428" checksum="EAFD3F6D5D13F825" modified="2010-04-20" version="1">MTHHAPVHRLRVAAARAASVPGEVGDNARTAAALVRLAHRHGVRLLVFGELFLPGYHPPTWASPACDVDVDDERLEPLRQAARDTGVTVLVGASVRSPGGRFIATLLVDPQGAVRDVYHKQNLCGPDENRWFTPGTHGSTLSFDGWRLGLGICYDATFPEHARAAALDGCHAYVTGGAYVVGGEHRRDTYHSARALDNTFYVVFADAVGGAAPWTFGGGSRVYDPEGRAVSEPVGDDLVVAELDPEELRRTRQEHTMLADLAGGPSPRYFTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5A3</accession>
    <name>D3Q5A3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019723.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4507"/>
    <dbReference type="EnsemblBacteria" id="ADD44152">
        <property type="protein sequence ID" value="ADD44152"/>
        <property type="gene ID" value="Snas_4507"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4507"/>
    <dbReference type="eggNOG" id="COG3173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074977_0_0_11"/>
    <dbReference type="OMA" id="EGYPHPW"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="40"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="305" mass="33086" checksum="F730EB7844D498F1" modified="2010-04-20" version="1">MTHTPHADGRAGIDVDLVERLIATQFPQWSDLPVTPVRVDGWDNRTYRLGEDKTVRLPTAPGYVPAVAKENTWLPRLAPRLPVPIPVPLGIGEPGEGYPHPWSVRRWLDGETATVERIADLSGFAESVAEFLLALQAVDATDGPIAGAHSFHRGADPAYYDDQTREALARLDGQIDTGAALAVWETALAAKWDGAPRWFHGDVAGGNLLVRDGKLSAVIDFGTCGVGDPACDLVMAWTFFDGDSRTAFRRAVGQDAAMWARARGWALWKALICLGGIDDNVTPEWLAGHRRVVSAVLAEHESRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5B7</accession>
    <name>D3Q5B7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4521</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019737.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4521"/>
    <dbReference type="EnsemblBacteria" id="ADD44166">
        <property type="protein sequence ID" value="ADD44166"/>
        <property type="gene ID" value="Snas_4521"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4521"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_11"/>
    <dbReference type="OMA" id="YGQDDAH"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="124"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="124"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="223" mass="24220" checksum="0A72CBB39ADA742B" modified="2010-04-20" version="1">MRVLVIEDEVRLAEAIARGLRRHGMAVDVVHDGLSGHQEATTVRYDVVVLDRDLPGMHGDKVCADIARRGALTRILMLTASGTLADKVNGLNIGADDYLSKPFAFDELVARVQALGRRATPAAPPVLHAADVELNPAAHTATRGGRDLELTHKEFGLLAELIKAGGTLVSTEELLDRVWDAHADPFTSTVRVTMRTLRRKLGEPPLIDNVPKVGYRINMAADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5M7</accession>
    <name>D3Q5M7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_6472</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021658.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6472"/>
    <dbReference type="EnsemblBacteria" id="ADD46087">
        <property type="protein sequence ID" value="ADD46087"/>
        <property type="gene ID" value="Snas_6472"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6472"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="AYHCIAG"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="12"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="277"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="370"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="433"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="286"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="375"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="440"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD46087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="497" mass="51574" checksum="4AB58941F6C0E607" modified="2010-04-20" version="1">MMTPGMKLGGRYRLDERIATGGMGDVWRATDEVLGREVAAKVLLPSLLNEPGFIERFRGEARVVATLTHPNIVRVYDYGESPLQGGGQVAYLVMEFVSGESLTARLQREGRLSAEQALPIVAQAAEALDAAHQAGVVHRDVKPGNLLLQPNGTVMLTDFGIARSALTGGLTQAGSVLGTAAYISPEQASGNPVTGQSDVYSLGIVAYQCLAGRRPFDSDNPVELAMRHMNDEPPPLPDDVPETARAFVASALAKDPAQRFATGEAMAQAARVAVGLAPGSPVTPTSPAPAVTDTSMTVPAPAQQPMAPRGSATPPPGRGLDVDPTSLNPEVSPHTPAPAQRRNKMLLMVAGATLLVVVLVATVWAIAAGTGGEDQAGDDGKDKTSESKQSDGEEDDGKIEIKTEDYLNKPPQQVKAALEKLGFEKVTVDGIGLYTSDITPDGKQDPTTPIKVSASRTRVEGGDNGSQTPGDTGGPSQSGGGTGPSKSCKPPGLGCKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5Z0</accession>
    <name>D3Q5Z0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015860.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0575"/>
    <dbReference type="EnsemblBacteria" id="ADD40289">
        <property type="protein sequence ID" value="ADD40289"/>
        <property type="gene ID" value="Snas_0575"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0575"/>
    <dbReference type="eggNOG" id="ENOG5033WT8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155293_0_0_11"/>
    <dbReference type="OMA" id="VWHASGF"/>
    <dbReference type="OrthoDB" id="2074700at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="137" mass="14476" checksum="6B7CD92F8A52F52C" modified="2010-04-20" version="1">MFTTGTTTKPGSLKLLRLAITLQTLSVFATPVTAGLLLTTPSGHVLHSGSSYTLFFVTLFHLIAAILAWRPGGGSATPVAAAAGFFALTLAQVFIGIAHLTTVHVPLGVLLFGLSVLQLAWVWNLRRADRIREGKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5Z8</accession>
    <name>D3Q5Z8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40297">
        <property type="protein sequence ID" value="ADD40297"/>
        <property type="gene ID" value="Snas_0583"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0583"/>
    <dbReference type="HOGENOM" id="CLU_457762_0_0_11"/>
    <dbReference type="OMA" id="PENESAW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="596" mass="59595" checksum="64B01B3265CCD85D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q624</accession>
    <name>D3Q624_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017770.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2517"/>
    <dbReference type="EnsemblBacteria" id="ADD42199">
        <property type="protein sequence ID" value="ADD42199"/>
        <property type="gene ID" value="Snas_2517"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2517"/>
    <dbReference type="eggNOG" id="COG0718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2289939_0_0_11"/>
    <dbReference type="OrthoDB" id="1691677at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="101" mass="11254" checksum="1A3B03B878BDDD76" modified="2010-04-20" version="1">MSLEDWLADMRTTMGRIELSLDEAKRAAAGTVTTAESPCGTVTATVDSSGKLLELAIEPGSFADHDVDSFGDAVVRAHNLAKRQWPHERRDRFRDAYFKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6B1</accession>
    <name>D3Q6B1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Export-related chaperone CsaA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2607</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017857.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2607"/>
    <dbReference type="EnsemblBacteria" id="ADD42286">
        <property type="protein sequence ID" value="ADD42286"/>
        <property type="gene ID" value="Snas_2607"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2607"/>
    <dbReference type="eggNOG" id="COG0073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065946_2_1_11"/>
    <dbReference type="OMA" id="FPEARNP"/>
    <dbReference type="OrthoDB" id="2038415at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008231">
        <property type="entry name" value="CsaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF37">
        <property type="entry name" value="PTHR11586:SF37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02222">
        <property type="entry name" value="chap_CsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="4">
        <location>
            <begin position="13"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="116" mass="12860" checksum="029C2E52A30CDB1D" modified="2010-04-20" version="1">MNEPVAPQVTIDDFTALDIRVGTVTRAEPFPKARRPAFRLWIDFGELGTRKSSAQITALYRVEELVGRQVLAVVNFPPRQVADFMSEVLVLGLTNADGEVVLVQPDRDVKPGLRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6F2</accession>
    <name>D3Q6F2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4551"/>
    <dbReference type="EnsemblBacteria" id="ADD44195">
        <property type="protein sequence ID" value="ADD44195"/>
        <property type="gene ID" value="Snas_4551"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4551"/>
    <dbReference type="eggNOG" id="COG1985">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036590_4_1_11"/>
    <dbReference type="OMA" id="CECGQEV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="6"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="215" mass="23524" checksum="237C579A59BDE1B0" modified="2010-04-20" version="1">MTVRRPWVLLSAAMSLDGYLDDATATRLVLSNDEDLNRVRQLRGHYDAILVGAETVRRDNPSLRAVDGPQPRKVTLTATGDLDPASRFFTTGAAPLVLCPPPVAEELRRRLGERAEVQSLPAGAGLAEILQTLWNLGVRRLMVEGGGSVHTQFLTQGLADELRLAVAPFFVGDAAAPRFTEPGKFPHDGQHRMRLYEVEHLGDMAVLHYSLDAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6L0</accession>
    <name>D3Q6L0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019824.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4610"/>
    <dbReference type="EnsemblBacteria" id="ADD44253">
        <property type="protein sequence ID" value="ADD44253"/>
        <property type="gene ID" value="Snas_4610"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4610"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_18_7_11"/>
    <dbReference type="OMA" id="TVVKMAT"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="148" mass="16804" checksum="07FD0A2BAA26D322" modified="2010-04-20" version="1">MSVPAWTSTWDDEFQPAFWMAKQAMTRAADAMFRRHGVRQGQQYLLMCLWHRDGQTPGEIATAIGLATPTVTRSATRMEAAGLLRRTPHPDDRRLVCLRLTDEGKRLRRVLNEEVSRLSERALSGLSAAERKQLTAMLRRVRENLTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Q4</accession>
    <name>D3Q6Q4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4654</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019868.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4654"/>
    <dbReference type="EnsemblBacteria" id="ADD44297">
        <property type="protein sequence ID" value="ADD44297"/>
        <property type="gene ID" value="Snas_4654"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4654"/>
    <dbReference type="eggNOG" id="COG1172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028880_0_2_11"/>
    <dbReference type="OMA" id="LPVSIWI"/>
    <dbReference type="OrthoDB" id="1254678at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="333" mass="34287" checksum="1E9A4F544E997297" modified="2010-04-20" version="1">MTALKRRLRAAADFLSGGTGTVFALLIVVFAIILIRDVSFAEPSSLMSFARKTAPLVVLAIGQYLVIVAGELDLSVGSLVGFQVVLAALLIDGQESRTIPVLLLMFGIGALVGLVNGLITTLLKVPSIITTLGMMLVLFGAIRLLTGGAPTGSLSEGFRVAGRRGIDIPGFAMVPWSVLIVVALGVAAAWTMRSAYGRTLMAVGDNPRASALSGVRVWQVRTLAFVGSGILATGAAVLVGGFAGVTAQVGQGMEFVAITAVVLGGVVLGGGRGTVLAAIAGAVTVEALFTLFNQLELPSTIRPTAQGLIIIAAVGYAARERIRRQPTPRLKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q736</accession>
    <name>D3Q736_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0301 protein Snas_0723</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0723</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0301 (AlgH) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0723"/>
    <dbReference type="EnsemblBacteria" id="ADD40435">
        <property type="protein sequence ID" value="ADD40435"/>
        <property type="gene ID" value="Snas_0723"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0723"/>
    <dbReference type="eggNOG" id="COG1678">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057596_2_0_11"/>
    <dbReference type="OMA" id="IYWGGDF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00758">
        <property type="entry name" value="UPF0301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003774">
        <property type="entry name" value="UPF0301"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30327">
        <property type="entry name" value="PTHR30327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02622">
        <property type="entry name" value="DUF179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="196" mass="20913" checksum="B776E35CAC44ADC1" modified="2010-04-20" version="1">MIPQEPGTVENQAGSLVGRLLVATPALQDPNFERTVVLLVSHESAGALGVVLNRATEVPVAEVLGDWSELAREPAVLFEGGPVQPEAAIALGWMRSGVGEPSCFKPFAGRLGTLDLSVDPEPLADRLEGMRVFAGYSSWGAGQLDDELKDGAWMVFDSLPGDPFGSRPEDLWAMVWRRQGGLLAAVAHYPADPSHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q759</accession>
    <name>D3Q759_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2653"/>
    <dbReference type="EnsemblBacteria" id="ADD42330">
        <property type="protein sequence ID" value="ADD42330"/>
        <property type="gene ID" value="Snas_2653"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2653"/>
    <dbReference type="HOGENOM" id="CLU_093862_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009339">
        <property type="entry name" value="DUF998"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06197">
        <property type="entry name" value="DUF998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="198" mass="21070" checksum="31E39200568551FA" modified="2010-04-20" version="1">MAIAGVVLAAASFVFMFVAMPEVDFLRHPVSIYENKQPGFTGYIIATAGIAVSCTALALTTTGWPRLVLATAALAFVVAAVFPTDPGTGVDTVAGYIHRYASGTGFGLVIIAGFLAFATTTGWRRPALLWLSVTNVVLMALVVINTFFPTFADGRDWRGLPQRLLLFTLAAVLVMLASNRASTAGSRRPREADAATRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q764</accession>
    <name>D3Q764_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017906.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2658"/>
    <dbReference type="CAZy" id="GH39">
        <property type="family name" value="Glycoside Hydrolase Family 39"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42335">
        <property type="protein sequence ID" value="ADD42335"/>
        <property type="gene ID" value="Snas_2658"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2658"/>
    <dbReference type="eggNOG" id="COG3664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049286_0_0_11"/>
    <dbReference type="OrthoDB" id="369827at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="371" mass="41390" checksum="D850F38E79BD7EE2" modified="2010-04-20" version="1">MRSLFRGSDGKFKLKAITTGVAAVALAITGTVGYAAYADAADFQVGMTHVNTSPDMHESDPEALESAKGVMKDVGGLQNAHLMGWGTANPWPDQNSDKRDWKSLDARMQLIDETGGTPVITLCSAPGWMKPSGDDWSMDEAPTKEYYDEYAQLAAETAERYPDVKYFQVWNEFKGFWDESKNRWDYEGFTEFYNKVYKAVKEVSPNAELGGPYVSLNTYKNADESPAPSKLQGEWGNVDQRDLDAIEYWLKNNDGAEFFTVDGGTETRDGFYPDVKQSGEKFKAITQWIAERTDLPIWWSEFYAFSAPQGPSSPEMMKSVLSGMREGGASVALWWQPEESAQPDNMPGLWTSTEKSDGGKKTEYVDIIENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7A2</accession>
    <name>D3Q7A2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017944.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2696"/>
    <dbReference type="EnsemblBacteria" id="ADD42373">
        <property type="protein sequence ID" value="ADD42373"/>
        <property type="gene ID" value="Snas_2696"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2696"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_13_2_11"/>
    <dbReference type="OMA" id="DGVGHTP"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="27"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="268" mass="29416" checksum="9E9CD68AA8ABDC4D" modified="2010-04-20" version="1">MTVSDDKPRTDDDLHVRQDGPRHAPALLLIHGSASSTRSWDQLVPLLTGVHHVIRVDLLGHGRSAKPDDGYEISEQARRVGETLDRLGVDEAIVVGHSSGGYTATALAERRPELVTALALINTGPSLDAFIAPNFALDPSQWPPTDEQLRQLASTGFGRADFPVPTELLDEVRAMTYHSLTRTMGASLEYLKRQVIPQRLTVVGKPLLVVYGEQDRRWRPSDFDDYRAVPGARVEMLTGVGHTPIIEDPPRTAETLLAFTSAHSPRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7D9</accession>
    <name>D3Q7D9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2734</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2734"/>
    <dbReference type="EnsemblBacteria" id="ADD42410">
        <property type="protein sequence ID" value="ADD42410"/>
        <property type="gene ID" value="Snas_2734"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2734"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="OMA" id="QWTGYNA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="87"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="308" mass="33922" checksum="CDB1F2048965B2AD" modified="2010-04-20" version="1">MTVTLLAERRRAAVDTTAARGRNRSRPRIAPWYFTGPAVALFAVFFAYPLVASLVESFQREDGTGASWAGLANYERLFSDPLVGGALLNIGLILVIQVPLMLSLALVLAQVLNQSWLRLRSTYRIGYFLPAVTTLVAYTIVFRVLLRADNGVFNQLIGLVGLSPVDWLNDPFWAKVALIASVTWRWTGYNMVILLAGLQAIPKQQYEAAAVDGAGPVSTYLRVIVPQLRPVILFCLITSTIGTLQLFDEPYILTEGGPDNATLTPVLYLYQVGFQQLDFGYASAIAWLVVAIIGLLSFAQFKFLGRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7G7</accession>
    <name>D3Q7G7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-Ala-His dipeptidase</fullName>
            <ecNumber evidence="2">3.4.13.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.13.20" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019880.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4666"/>
    <dbReference type="EnsemblBacteria" id="ADD44309">
        <property type="protein sequence ID" value="ADD44309"/>
        <property type="gene ID" value="Snas_4666"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4666"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029469_2_0_11"/>
    <dbReference type="OMA" id="HITIPGF"/>
    <dbReference type="OrthoDB" id="275025at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="202"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="455" mass="48198" checksum="BD861318F163D20D" modified="2010-04-20" version="1">MSLSRSDLRSAVDAGMPTVIEDLKQLARIPSVAFEGFDHSHVTRSAEAVAELLRGAGMDDVRIVTAKGASGQTGQPAVIGRKAAPAGAPHVLLYAHHDVQPAGDYDDWEQDDPFEPQLRGERLFGRGCADDKAGVMAHVAALRAFGDDLPVGVTVFVEGEEEFGSDSLENLITENRDLLAADVIVIADSANWDVGHPALTTSLRGVINAYVEVRTLNQAVHSGMFGGAVPDALTALCRLLGTLHDETGDVAVEGLKTGTAAPLDLPEERLRAESGMVDGVEFIGSGRLVERLWTKPTATVLGIDAPGARESANALQPSARAKISLRLAPGDESVSAFEAVKRHLEARVPWGAQLTVTLDHGGNPCQIDARGERYDAARAAFAEAWDGVEPVDMGVGGAIPFIATFQELFPDAAILVTGVEDPDSRAHGPNESLHLAEFTRACRAEALLLHNLSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Z0</accession>
    <name>D3Q7Z0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4396 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0783</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016066.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0783"/>
    <dbReference type="EnsemblBacteria" id="ADD40495">
        <property type="protein sequence ID" value="ADD40495"/>
        <property type="gene ID" value="Snas_0783"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0783"/>
    <dbReference type="eggNOG" id="ENOG502ZV2M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100611_0_0_11"/>
    <dbReference type="OMA" id="TTPVNKW"/>
    <dbReference type="OrthoDB" id="1709295at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025509">
        <property type="entry name" value="DUF4396"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14342">
        <property type="entry name" value="DUF4396"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4396" evidence="2">
        <location>
            <begin position="29"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="170" mass="17720" checksum="4431F66A6E4EC548" modified="2010-04-20" version="1">MFLGMSHSHEHHSTDAHAQHAHHGHGPVSWKMAAVATLHCLTGCAIGEVLGMVIGTALGWGNAPTMVLAIVLAFVFGYSLTMFGVRKAGLGLAGMIKVALAADTVSIIVMEIADNGMLLIIPGAMDAHLDSGLFWGALAVAFLVAFVITTPVNKWLIGKGKGHAVVHGMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8P0</accession>
    <name>D3Q8P0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">5'-Nucleotidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4841</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020053.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4841"/>
    <dbReference type="EnsemblBacteria" id="ADD44482">
        <property type="protein sequence ID" value="ADD44482"/>
        <property type="gene ID" value="Snas_4841"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4841"/>
    <dbReference type="eggNOG" id="COG0737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005854_5_2_11"/>
    <dbReference type="OMA" id="LITHVYP"/>
    <dbReference type="OrthoDB" id="1884225at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005126348" evidence="1">
        <location>
            <begin position="27"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="33"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="3">
        <location>
            <begin position="381"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="586" mass="61852" checksum="D30DF52CA233863E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q919</accession>
    <name>D3Q919_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0917</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016199.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0917"/>
    <dbReference type="EnsemblBacteria" id="ADD40628">
        <property type="protein sequence ID" value="ADD40628"/>
        <property type="gene ID" value="Snas_0917"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0917"/>
    <dbReference type="HOGENOM" id="CLU_2107517_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045428">
        <property type="entry name" value="EACC1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19953">
        <property type="entry name" value="EACC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="115" mass="12503" checksum="83634ADF187EBCAE" modified="2010-04-20" version="1">MVEVRISVAGGDRDGVELLAWLRRDPEARKVAIEPEPHEDGRPPDIIRAVINTVTQLGALVMAIVAFRATRSRSTCPQVSFTAASGARVLVQDADAETIKFVWDVINSAVPPQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q987</accession>
    <name>D3Q987_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2894"/>
    <dbReference type="EnsemblBacteria" id="ADD42569">
        <property type="protein sequence ID" value="ADD42569"/>
        <property type="gene ID" value="Snas_2894"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2894"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2304302_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="29"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="100" mass="10775" checksum="DFE347B95F651A83" modified="2010-04-20" version="1">MEALAASRTVYVVDLEDALRDSAANMFVHKELATTELVAATTQPTLVVWGDQDTIMPPAQAARFAKLIPDAEAHMVDDCGHALTLDCPDETTALMKAFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9A1</accession>
    <name>D3Q9A1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018154.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2908"/>
    <dbReference type="EnsemblBacteria" id="ADD42583">
        <property type="protein sequence ID" value="ADD42583"/>
        <property type="gene ID" value="Snas_2908"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2908"/>
    <dbReference type="eggNOG" id="COG3173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007526_0_0_11"/>
    <dbReference type="OMA" id="QCMAWRI"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="35"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="347" mass="37690" checksum="125A753B90738F16" modified="2010-04-20" version="1">MTAARPDTEQAVDPARIRPWLDELGIAVSGELTIDRVGLGQSNLTYVACDADGHKWVLRRPPLGTLLASAHDVVREARIMAALRDTTVPVPSILGVSDDAAVCDAPLVLMEHVDGQVLDHLAVARTLSSRQRHDIAASLIDTLATVHTVDLEAVGLNDLASHKPYAARQLKRWSSQWEKSKTRESSALDNLTERLWAAAPPQRELTLVHGDFHLNNLITDPATGRIRAVLDWELATLGDPLADMGSLLAYWAEPGKAAIPGFDVTTLDGFPSHAELAERYLSATGRDAHALRYWHVLGLWKVAVIAEGVLRRALDEPKNRAASGTPTTDIIDGLVDRARRIADDAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9A4</accession>
    <name>D3Q9A4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018157.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2911"/>
    <dbReference type="EnsemblBacteria" id="ADD42586">
        <property type="protein sequence ID" value="ADD42586"/>
        <property type="gene ID" value="Snas_2911"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2911"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_11"/>
    <dbReference type="OMA" id="WGLYNTK"/>
    <dbReference type="OrthoDB" id="831053at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="13"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="333" mass="34297" checksum="FAC4D173BA3B8A4D" modified="2010-04-20" version="1">MKALRCHQTGEPGEVLSVEEIPDPTVADGQLLVSVLAAPLSFPDLLLCRGQYQFAPPLPMTLGVELCGTVLAVGAGVNRFAVGDRVIGNPAPPDGAFAELAILEDSAAYPAPKALDDAQASALGIAYQTGWFALHRRARLQPGETLLVHAAAGGVGSAAVQLGKAAGATVIGVVGGADKARHCAELGADLVIDRRDADFVKAVKDFTDGRGADVIFDPVGGDAYAGSTKCVAFEGRILVVGFAGGTIPKPGLNHALIKNYSILGLHWGLYLRHDPGAVVECHRHLTTLADAGAITPLVTERLSLADTADGLRRLGDGHTSGRVVCEPTAGSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9B5</accession>
    <name>D3Q9B5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018168.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2922"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42597">
        <property type="protein sequence ID" value="ADD42597"/>
        <property type="gene ID" value="Snas_2922"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2922"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_7_5_11"/>
    <dbReference type="OMA" id="MGTYNEE"/>
    <dbReference type="OrthoDB" id="1064289at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="217" mass="24129" checksum="FC5D6715A7E4B3AD" modified="2010-04-20" version="1">MTEADVILPCLNEAEALPWVLERIPVRFRPIVVDNGSTDGSADLAASLDATVVTETRRGFGAACHAGLEAATADIVCFCDCDASMDPRLLRSMVESIRDDDTDLVLGRRRPTTMRAWPLHARFGNIALARMVRRRTGTRLRDLGPMRAARRTALLDLGITDRRSGYPLEMVVKAADAGWRIDEVDIPYLPRSGKSKVTGTWRGTWQAVHDMREVLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9D7</accession>
    <name>D3Q9D7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Error-prone DNA polymerase</fullName>
            <ecNumber evidence="2 11">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">dnaE2</name>
        <name evidence="14" type="ordered locus">Snas_2944</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the DNA polymerase type-C family. DnaE2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2 11"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2944"/>
    <dbReference type="EnsemblBacteria" id="ADD42619">
        <property type="protein sequence ID" value="ADD42619"/>
        <property type="gene ID" value="Snas_2944"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2944"/>
    <dbReference type="eggNOG" id="COG0587">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001600_4_0_11"/>
    <dbReference type="OMA" id="VAKSHHW"/>
    <dbReference type="OrthoDB" id="561611at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01902">
        <property type="entry name" value="DNApol_error_prone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011708">
        <property type="entry name" value="DNA_pol3_alpha_NTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040982">
        <property type="entry name" value="DNA_pol3_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023073">
        <property type="entry name" value="DNA_pol_error_prone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029460">
        <property type="entry name" value="DNAPol_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004805">
        <property type="entry name" value="PolC_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294">
        <property type="entry name" value="PTHR32294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294:SF4">
        <property type="entry name" value="PTHR32294:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07733">
        <property type="entry name" value="DNA_pol3_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17657">
        <property type="entry name" value="DNA_pol3_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14579">
        <property type="entry name" value="HHH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00594">
        <property type="entry name" value="polc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 11" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="POLIIIAc" evidence="13">
        <location>
            <begin position="64"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD42619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1105" mass="119669" checksum="9AB038BDF1BEBA9C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9H7</accession>
    <name>D3Q9H7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018230.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2985"/>
    <dbReference type="EnsemblBacteria" id="ADD42659">
        <property type="protein sequence ID" value="ADD42659"/>
        <property type="gene ID" value="Snas_2985"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2985"/>
    <dbReference type="HOGENOM" id="CLU_129901_0_0_11"/>
    <dbReference type="OMA" id="VRIAVWA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="141" mass="14757" checksum="F7A61372937F7848" modified="2010-04-20" version="1">MRFVRVVLIVTGVGFAAWGAAGLLAEQSPADLTGLAVWLGMAVAVHDGLLAPLSLLAGALAWRALRPLPRPVRQFTTGGLLVAGTLALLALPLLIRYPVVSNPTALPQSYGSNLGWLLVTVLGATGVVTLAGWWRGRRGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Q8</accession>
    <name>D3Q9Q8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4966</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020175.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4966"/>
    <dbReference type="EnsemblBacteria" id="ADD44604">
        <property type="protein sequence ID" value="ADD44604"/>
        <property type="gene ID" value="Snas_4966"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4966"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="WYMANAR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1030" mass="113031" checksum="CFC261BB9ABCEDA0" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9R2</accession>
    <name>D3Q9R2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase class-III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4970"/>
    <dbReference type="EnsemblBacteria" id="ADD44608">
        <property type="protein sequence ID" value="ADD44608"/>
        <property type="gene ID" value="Snas_4970"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4970"/>
    <dbReference type="eggNOG" id="COG0160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_10_0_11"/>
    <dbReference type="OMA" id="FWGWQAH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="431" mass="45860" checksum="A0F8A7DC39A21823" modified="2010-04-20" version="1">MEHKALTDRHRAVLPNWVSPMYAEPIEFVSASGRRVVDATGKSYLDFFGGVLTTMVGYDIPEIREAVDRQLSTGITHSSTLYLIRNQVILAEKIAAVSGIPDAKVFLGNSGSEATETALLLATQYRRSNQILAMRNSYHGRTFGAVGVTGNKGWSASALTPFNVSYLHSGDRLRGLFAGMSDAEYIERSVADLREVLATTTSGDVACLIAEPIQGVGGFVMPPDGYFKAIQEVLAEHGILWVCDEVQTGWGRTGSHLWGYQAHDAVPDILTFAKGIGNGFALGGVVARAEVMDCLSAISFNTFGGNPLAAAAGIAVLDYLRDNDLQHNAARTGAIIHAGLTEQARRSPIVAEVRGKGLMIAIEFVAADTTRPDPAAALRVLEACRRDGLLVGKGGLYGNVIRMGPPLTLTESEAAEGLAILTNAIDEEAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Z7</accession>
    <name>D3Q9Z7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0999</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016280.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0999"/>
    <dbReference type="EnsemblBacteria" id="ADD40709">
        <property type="protein sequence ID" value="ADD40709"/>
        <property type="gene ID" value="Snas_0999"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0999"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="IEGHVQY"/>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="300" mass="32738" checksum="CD0E57695DCB0994" modified="2010-04-20" version="1">MENAIHTESLVKHFGQVHALDGLDLSVRTGEVHGFLGPNGAGKSTAIRVLLGLLRADGGTASLLGGDPWRQATKLHRRLAYVPGDVNLWPNLSGGEVIDLLGRLRGGLDPKRRKDLLERFDLDPRKKGRTYSKGNRQKVALIAALASDVELLLLDEPTSGLDPLMEQVFRDCITDERRDGRTVLLSSHILSEVEALCDRVSIIRNGKIVESGTLSELRHLTRTSIHAELISSPNGLSSLEGVHDLVVDGTHVRCQVDTAKLNSVLAKLTQTGVDSLTCTPPTLEELFMRHYSDDITKAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA46</accession>
    <name>D3QA46_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ADD40758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1048"/>
    <dbReference type="EnsemblBacteria" id="ADD40758">
        <property type="protein sequence ID" value="ADD40758"/>
        <property type="gene ID" value="Snas_1048"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG2318">
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    </dbReference>
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    <dbReference type="OrthoDB" id="2047691at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007061">
        <property type="entry name" value="DUF664"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04978">
        <property type="entry name" value="DUF664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="187" mass="21156" checksum="3DD9BE94811431CA" modified="2010-04-20" version="1">MTSSVPPTVDERDNLIKYVAQQRDTFRYVAHGLTDEQARMQPTAGTLSIGGLIKHIAQMERSWVATVTQTEYQVDYVNGFTMLADETLEGLLADLAKAGEETERALADLDMDHPVPVPDAPWFPKDVENWSVRWVLAHLIEEIARHAGHADIIREFIDGKTMYELQAMADGWHEQYLAMQNNWGGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA51</accession>
    <name>D3QA51_STANL</name>
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        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Snas_1053</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016334.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1053"/>
    <dbReference type="EnsemblBacteria" id="ADD40763">
        <property type="protein sequence ID" value="ADD40763"/>
        <property type="gene ID" value="Snas_1053"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1053"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_3_0_11"/>
    <dbReference type="OMA" id="KNTINVM"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18947">
        <property type="entry name" value="HAMP_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="98"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="195"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="287"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="379"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="471"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="563"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="655"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="747"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="11">
        <location>
            <begin position="1044"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="12">
        <location>
            <begin position="1326"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1280"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="975"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1288"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="1376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD40763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1458" mass="157547" checksum="E432F585710F5DB0" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA76</accession>
    <name>D3QA76_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1078</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ADD40788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1078"/>
    <dbReference type="EnsemblBacteria" id="ADD40788">
        <property type="protein sequence ID" value="ADD40788"/>
        <property type="gene ID" value="Snas_1078"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1078"/>
    <dbReference type="eggNOG" id="COG0329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_703265_0_0_11"/>
    <dbReference type="OMA" id="CGVGTDQ"/>
    <dbReference type="OrthoDB" id="1002834at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009334">
        <property type="entry name" value="DUF993"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06187">
        <property type="entry name" value="DUF993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="376" mass="40979" checksum="F7288748A3E20DF5" modified="2010-04-20" version="1">MTTIDLPGHGRYELRQPTVFPAVESFPSRTIYAAAHVVADPLADNGPGRPATLDWDATMAFRRHLWSQGLGVAEAMDTAQRGMGLDWKATRELIWRTVSEADGAPLACGVGTDQLVGPASMSEVAEAYIEQLLTVGVTGATPILMCSRALAAVAKTPEDYRSVYRQLLERVERPVILHWLGSMFDPALTGYWGSTDLKLAAESLLNLIAEYPERIDGVKISLLDAEAEIAFRRALPDSVVCYTGDDFNYPWLIEGDEHGHSHALLGIFDPLARFASAAAARLDAGDAAGFRAILDPTVPLARKVFETPTFNYKTGVVFLAWLSGHQDHFRMVGGLESARSITHLTEVFTLADRIGLFPDPELAADRMRSLLTVAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAE7</accession>
    <name>D3QAE7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3059</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3059"/>
    <dbReference type="EnsemblBacteria" id="ADD42730">
        <property type="protein sequence ID" value="ADD42730"/>
        <property type="gene ID" value="Snas_3059"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3059"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1014" mass="111084" checksum="0FA6D316F8CBB190" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAH0</accession>
    <name>D3QAH0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018324.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3082"/>
    <dbReference type="EnsemblBacteria" id="ADD42753">
        <property type="protein sequence ID" value="ADD42753"/>
        <property type="gene ID" value="Snas_3082"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3082"/>
    <dbReference type="eggNOG" id="COG0111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_0_11"/>
    <dbReference type="OrthoDB" id="1435073at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh_C" evidence="1">
        <location>
            <begin position="102"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="317" mass="33744" checksum="029926E0948DC8FD" modified="2010-04-20" version="1">MWIHVVSAHPNFTLEAELRVLVERNPHWRFTIGDEPPADAGYQVLIASRPTRELLSASPRLTTVQLPFSGVPAVTREVMADFPHLELRSLHHNAGPTAELALGLVLAAARGIVPADTGMRSGDWTSRFVPPRPTMLLDGHGATVVGYGEIGRRVARGLAALGMRVRATRASVTSAYTDGDVEVRPADALTELLPDSRVLVLTVPASPATTGLIGEAELALLPVPATLVNVSRATVVDEKALYEKLRGGDLAAGLDVWWDEAIEPDAVHGVPASAYPFHELPNVVLSPHRGGAFSLPESAVLRAAHLEKALAEIASGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAI7</accession>
    <name>D3QAI7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018341.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3099"/>
    <dbReference type="EnsemblBacteria" id="ADD42770">
        <property type="protein sequence ID" value="ADD42770"/>
        <property type="gene ID" value="Snas_3099"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3099"/>
    <dbReference type="eggNOG" id="ENOG5032ZIV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122355_1_0_11"/>
    <dbReference type="OMA" id="WSETGDA"/>
    <dbReference type="OrthoDB" id="1986389at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013434">
        <property type="entry name" value="CHP02611"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019099">
        <property type="entry name" value="Uncharacterised_PGPGW_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09656">
        <property type="entry name" value="PGPGW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02611">
        <property type="entry name" value="TIGR02611"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="143" mass="15611" checksum="506C7890B015C924" modified="2010-04-20" version="1">MAETRTDDKPADEARGGIHGFLDRFRTTRMGRLGVRIAVTAVGGAVVVAGLIMIPFPGPGWAVVIAGLAILALEYVWAHHLMSFTSRQVKAWLHWVGRQHLAVRLLIGVGCFVFVAAILWISLKLSFGFDYIQWGLGELGTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAN1</accession>
    <name>D3QAN1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="6">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="6">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="6">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="6">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="6" type="primary">folD</name>
        <name evidence="9" type="ordered locus">Snas_5040</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="6"/>
    <dbReference type="EC" id="3.5.4.9" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020248.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5040"/>
    <dbReference type="EnsemblBacteria" id="ADD44677">
        <property type="protein sequence ID" value="ADD44677"/>
        <property type="gene ID" value="Snas_5040"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5040"/>
    <dbReference type="eggNOG" id="COG0190">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034045_2_1_11"/>
    <dbReference type="OMA" id="KACSKEI"/>
    <dbReference type="OrthoDB" id="1449514at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3 6" id="KW-0521">NADP</keyword>
    <keyword evidence="1 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THF_DHG_CYH" evidence="7">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="THF_DHG_CYH_C" evidence="8">
        <location>
            <begin position="121"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="162"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="276" mass="28304" checksum="7EF31CA62F95EFE6" modified="2010-04-20" version="1">MRDIDGRAMAKAIGAEVAATAERLRADGVVPTLAVVVPTDDESTAWYVRSIERAAQNRGVECRVLQLEDPSAERLKSELDTLSADDSVHGIICQTPLPEGVTLADVGEHIAVAKDVDGANPASLGRLAAGLDTFAPATAAAVAEILRQDEVALKGKNVTIIGRSTVVGKPAALLLLAEHATVTICHSRTENLPEVCARADVLVAAVGRPEMVTAEYVKPGAIVIDVGTNPTAEGGLVGDVNAESVASVAGALTPVPGGVGPVTTQLLLRHTVQAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAU3</accession>
    <name>D3QAU3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Daunorubicin resistance ABC transporter ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5104</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020310.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5104"/>
    <dbReference type="EnsemblBacteria" id="ADD44739">
        <property type="protein sequence ID" value="ADD44739"/>
        <property type="gene ID" value="Snas_5104"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5104"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="CHRVGIM"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043215">
        <property type="term" value="P:daunorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900753">
        <property type="term" value="P:doxorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005894">
        <property type="entry name" value="DrrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01188">
        <property type="entry name" value="drrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="324" mass="35162" checksum="985AFF2F3B6B9A77" modified="2010-04-20" version="1">MTTPAVRVRGLTKSFGSVEAVRGIDLDVGKGEMFGFLGPNGAGKTTTIKILCTLSTPTSGTAEVAGWDVGRDRAAVRRAIGLVFQEPTLDAYLTAEQNLAFHGELYGMPRSLLRERIGVVLEMVDLADRRRDAVKTFSGGMKRRLEIGRGLMHAPSVLFLDEPTIGLDPQTRAAIWDYIGQLRRTQDITIFVTTHYMDEADHCDRIAIIDDGRIVVTDTPDALKRGVGADRVQLRTADDAAAIVRLAERFGIEAATHEHQVTFAVSEGAQFIPRLVTELGVGIDSVTVTRPSLDDVFMAHTGRTLRDAETGGTKGALAMMGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAV1</accession>
    <name>D3QAV1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Polynucleotide phosphorylase</fullName>
            <shortName evidence="7">PNPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pnp</name>
        <name evidence="10" type="ordered locus">Snas_5112</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n)</text>
            <dbReference type="Rhea" id="RHEA:22096"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the polyribonucleotide nucleotidyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020318.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5112"/>
    <dbReference type="EnsemblBacteria" id="ADD44747">
        <property type="protein sequence ID" value="ADD44747"/>
        <property type="gene ID" value="Snas_5112"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5112"/>
    <dbReference type="eggNOG" id="COG1185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004217_2_2_11"/>
    <dbReference type="OMA" id="LHILDVM"/>
    <dbReference type="OrthoDB" id="122725at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01595">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014069">
        <property type="entry name" value="GPSI/PNP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015848">
        <property type="entry name" value="PNPase_PH_RNA-bd_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036456">
        <property type="entry name" value="PNPase_PH_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="PTHR11252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03726">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46915">
        <property type="entry name" value="SSF46915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03591">
        <property type="entry name" value="polynuc_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02696">
        <property type="entry name" value="pppGpp_PNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="9">
        <location>
            <begin position="662"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="729"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="729"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="808"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="525"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="531"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD44747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="825" mass="87768" checksum="AC1B24896610FD43" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB21</accession>
    <name>D3QB21_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1128</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016409.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1128"/>
    <dbReference type="EnsemblBacteria" id="ADD40838">
        <property type="protein sequence ID" value="ADD40838"/>
        <property type="gene ID" value="Snas_1128"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1128"/>
    <dbReference type="eggNOG" id="COG3801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_138549_2_0_11"/>
    <dbReference type="OMA" id="WCAAPPG"/>
    <dbReference type="OrthoDB" id="1817663at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007351">
        <property type="entry name" value="YjbR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038056">
        <property type="entry name" value="YjbR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04237">
        <property type="entry name" value="YjbR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142906">
        <property type="entry name" value="SSF142906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="120" mass="13525" checksum="398F994707710D4B" modified="2010-04-20" version="1">MTDDPIERLRPLCLALPEATERPSHGEPAWFVRDKKLFVMAAQHHHDDRLGFWCAAAPGEAAALVAGDPRRFFIPPYVGHRGWLGVYLDVDGVDWDEIAEIVTDAYRHVAPKRLVALLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB46</accession>
    <name>D3QB46_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1153"/>
    <dbReference type="EnsemblBacteria" id="ADD40863">
        <property type="protein sequence ID" value="ADD40863"/>
        <property type="gene ID" value="Snas_1153"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1153"/>
    <dbReference type="HOGENOM" id="CLU_2620332_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="78" mass="8511" checksum="254BD1012FEF00A5" modified="2010-04-20" version="1">MDIHHSVVVSRSNGTQKARVIGVNRRNDQLTTTAEFDFTPQWARFIGGAGRPEGSGSAWTSTTWTTDEPVVSTYALGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB88</accession>
    <name>D3QB88_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplN</name>
        <name evidence="6" type="ordered locus">Snas_1195</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016476.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1195"/>
    <dbReference type="EnsemblBacteria" id="ADD40905">
        <property type="protein sequence ID" value="ADD40905"/>
        <property type="gene ID" value="Snas_1195"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1195"/>
    <dbReference type="eggNOG" id="COG0093">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095071_2_1_11"/>
    <dbReference type="OMA" id="AKEVLCI"/>
    <dbReference type="OrthoDB" id="1799923at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="122" mass="13349" checksum="3E8466C1670C7F0A" modified="2010-04-20" version="1">MIQQESRLRVADNTGAREVLCIRVLGGSGRRYAGIGDLFVGTVKDAIPGAGVKKGDVVRAVVVRSAKERRRPDGSYIKFDENAAVLIKDDGEPRGTRIFGPVGRELRDKRFMKIISLAPEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB98</accession>
    <name>D3QB98_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1205"/>
    <dbReference type="EnsemblBacteria" id="ADD40915">
        <property type="protein sequence ID" value="ADD40915"/>
        <property type="gene ID" value="Snas_1205"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1205"/>
    <dbReference type="HOGENOM" id="CLU_3376198_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="34" mass="4148" checksum="C9C0198C9C3619F0" modified="2010-04-20" version="1">MCFVGRLSEWQSAHEHLEGPNTQRERYTRYRVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBF1</accession>
    <name>D3QBF1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018404.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3162"/>
    <dbReference type="EnsemblBacteria" id="ADD42833">
        <property type="protein sequence ID" value="ADD42833"/>
        <property type="gene ID" value="Snas_3162"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3162"/>
    <dbReference type="HOGENOM" id="CLU_1474316_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="183" mass="19378" checksum="82FEAC7AFC52D1D6" modified="2010-04-20" version="1">MTALLTTARLAVSGGSADWSFAYRDGHGGVVATAAPVTAEQPPHGWRGWFSTDHNLGRVVVRVDDPAGTPLFFADRQPVPPSTGATPPCAILAPHGGLLGRVAVDTARRHRAHRILGADDTVLFEVVWEPSGRYGDFTAPDGSVAARYHPAQGLWFQRRLPSAEHTLVVAFPVALALLGTTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC12</accession>
    <name>D3QC12_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020472.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44901">
        <property type="protein sequence ID" value="ADD44901"/>
        <property type="gene ID" value="Snas_5267"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5267"/>
    <dbReference type="eggNOG" id="ENOG5033S7D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_813566_0_0_11"/>
    <dbReference type="OrthoDB" id="1688592at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049865" evidence="1">
        <location>
            <begin position="29"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="348" mass="37623" checksum="49E491DFE6AFF688" modified="2010-04-20" version="1">MSRKLGWRIALGAVALATGLAFTPLAFADDGVASANDDPSFLQVYDANVENLPEAGDTCPGDWQDLVYYMKTQDAAPDLYLIQQLSGSGDQRGDLQYLIARMEKEFGQNYDGILAQNNPGKGPQKCAPQKGYQTNGIIFRVDRFEKVKTDNNTWLAQSKSSGSCRNSDQDRTRGVKIKLRDKLANKTVTAASVHWPTAASDGPPCADVNAKETAKEMTEDGYGADQLILGGDMNYTDAGSNGGTDFRSWYKAMNGDLKGGYGFRDAVYAACAAASDPNKCRASNWTVGGKSRIDFLMAKTGAGKMPVIDGVRSPTFDEGDAAALKFEGKDDGKLNYSDHRAVQARVHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU21</accession>
    <name>D3PU21_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cyclic dehypoxanthine futalosine synthase</fullName>
            <shortName evidence="6">Cyclic DHFL synthase</shortName>
            <ecNumber evidence="6">1.21.98.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dehypoxanthine futalosine cyclase</fullName>
            <shortName evidence="6">DHFL cyclase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Menaquinone biosynthetic enzyme MqnC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mqnC</name>
        <name evidence="8" type="ordered locus">Snas_1258</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dehypoxanthine futalosine + S-adenosyl-L-methionine = 5'-deoxyadenosine + cyclic dehypoxanthinylfutalosinate + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:33083"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58864"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64270"/>
            <dbReference type="EC" id="1.21.98.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. MqnC family.</text>
    </comment>
    <dbReference type="EC" id="1.21.98.1" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016538.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1258"/>
    <dbReference type="EnsemblBacteria" id="ADD40967">
        <property type="protein sequence ID" value="ADD40967"/>
        <property type="gene ID" value="Snas_1258"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1258"/>
    <dbReference type="eggNOG" id="COG1060">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040406_1_0_11"/>
    <dbReference type="OMA" id="ATMMFGS"/>
    <dbReference type="OrthoDB" id="419725at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046992">
        <property type="term" value="F:oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00992">
        <property type="entry name" value="MqnC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045567">
        <property type="entry name" value="CofH/MnqC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022431">
        <property type="entry name" value="Cyclic_DHFL_synthase_mqnC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034405">
        <property type="entry name" value="F420"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020050">
        <property type="entry name" value="FO_synthase_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43076">
        <property type="entry name" value="PTHR43076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19288">
        <property type="entry name" value="CofH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00343">
        <property type="entry name" value="aminofutalosine_synthase_(mqnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03699">
        <property type="entry name" value="menaquin_MqnC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00423">
        <property type="entry name" value="TIGR00423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="52"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="385" mass="42890" checksum="4F86F2338825406C" modified="2010-04-20" version="1">MSTEIAEILQRGADGGRITTEEALLLYTEAPFHELGEAADAVRRRRYPEGIVTYLIDRNINYTNVCVTACKFCAFYRAPKHKEGWSHDLDEILRRCAEAIDLGATQVMLQGGHHPEFGVEYYEELFGAVKREFPQLAIHSIGPSEIGHMAKVSEVSIEEAIKRIKAAGLDSIAGAGAEMLPERPRKALAPLKESGERWCEIMEVAHGLGLESTATMMMGTGETNAERIEHLRMIRDVHDKTGGFRAFIPWTYQPENNHLKGRTQATTVEYLRMLATARLYFNEIAHLQSSWLTTGKAAGQVSLHMGVDDLGSIMLEENVISSAGARHRSNLHGLIDMIRSAGRVPAHRNTLYEHLSVHWTPEDDPTDERVRSHVSSIALPLVEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUI5</accession>
    <name>D3PUI5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3332</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018569.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3332"/>
    <dbReference type="EnsemblBacteria" id="ADD42998">
        <property type="protein sequence ID" value="ADD42998"/>
        <property type="gene ID" value="Snas_3332"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3332"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="HNEGEFE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="15"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="815"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="15"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="266"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1025" mass="112677" checksum="CF3086998E29A98C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV42</accession>
    <name>D3PV42_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-L-isoaspartate O-methyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Protein-beta-aspartate methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1388</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1388"/>
    <dbReference type="EnsemblBacteria" id="ADD41095">
        <property type="protein sequence ID" value="ADD41095"/>
        <property type="gene ID" value="Snas_1388"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1388"/>
    <dbReference type="eggNOG" id="COG2518">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037629_0_1_11"/>
    <dbReference type="OMA" id="WAWLDDP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="370" mass="40868" checksum="85F0B33942A01AC4" modified="2010-04-20" version="1">MNVADDWRERAARLADYLASEGLDPAWTAVFARVPRHEFVNGGHAVDTDGVAPDAADWNREELLREAYADQVVVTRYETAGGEPVATSSASQPLIVAIMLRLLNVRDDSRVLEIGTGPGYNACLLCTRLGEQRVTSVEIQSDVVADARDNLARVGFHPHLEVTDGTLGCPSRAPYDRVIATCGLSRIPEAWLDQLAPHARVVAPMNFGGALAVLDRRPDGSLSGRFPREAGFFMELRHPGDSWEPKPPGYLAVPPRVIKTDIDVDVLGDMEFRLWLELAAPDVQVHPSRVADGRLVEVRISTPDTRIDIEVDGAIRAVEYGKSLWRTVEGLAADWEAHGRPDRGRMGMTVTPERQWVWLDAEDSDVLWEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVE1</accession>
    <name>D3PVE1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016765.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1490"/>
    <dbReference type="EnsemblBacteria" id="ADD41194">
        <property type="protein sequence ID" value="ADD41194"/>
        <property type="gene ID" value="Snas_1490"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1490"/>
    <dbReference type="HOGENOM" id="CLU_1685499_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="156" mass="17411" checksum="9DF4E2B695392BF5" modified="2010-04-20" version="1">MGKNSDNLGADLHQLQIAGRAMLPDVGRSYSQASRDLHNVGAGYDPRQPAMGLILSFRDQIQDYFVATHHAMINNGAALVTIAKEYAKTDWGAAQKMREDWENRMASPILNEPRPPMPEPKTSADETYETTREVMFEPDPNSPSGVVEVTKWVPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVI1</accession>
    <name>D3PVI1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018666.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3431"/>
    <dbReference type="EnsemblBacteria" id="ADD43095">
        <property type="protein sequence ID" value="ADD43095"/>
        <property type="gene ID" value="Snas_3431"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3431"/>
    <dbReference type="eggNOG" id="ENOG5032ZFQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102900_1_0_11"/>
    <dbReference type="OrthoDB" id="1538348at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="166" mass="18307" checksum="7367EE538BC6A74C" modified="2010-04-20" version="1">MVLNLLIGVHISAGLLAVGCGAAAMVVRKQPVRHPWLGRTYLTALVGLVVTAIGLVTFRPHTAYLLLLGTAALATAGIGFAARRMRWRGWLRHHLAAMGTSYILMLTAFYVDNGPRLPLWNLLPPLMFWFLPALVGLPLLLWALARHRIHPNNRRPLRRSPEGGTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVI7</accession>
    <name>D3PVI7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosidase PH1107-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3437</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 130 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3437"/>
    <dbReference type="EnsemblBacteria" id="ADD43101">
        <property type="protein sequence ID" value="ADD43101"/>
        <property type="gene ID" value="Snas_3437"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3437"/>
    <dbReference type="eggNOG" id="COG2152">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046648_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007184">
        <property type="entry name" value="Mannoside_phosphorylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34106">
        <property type="entry name" value="PTHR34106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04041">
        <property type="entry name" value="Glyco_hydro_130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016202">
        <property type="entry name" value="PH1107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="340" mass="36945" checksum="55BCF8633C7AFF37" modified="2010-04-20" version="1">MSRTPPDAIFGDREGCQLREPFDKPWGATALPSFTRHPGNPVLTAADWPTPVATIGNPGAAHDGHGIVLLCGVEDRRGMTTLNIARSRDGVGDWSIESQPLIEPRSCGSRHWSGVRDGRLTWVPELNGWVIAFTAFGHSGTGVALAFTSDFKDVVPLGVAAPPDDQSGVLLPRRADGEFVLLHRPMSPMSLRADVWSSRSPDLLRWHGSRPVLPARPTPWWDSAGVGVGPPPIETDHGWLTVYSGDKRVDDRTVRRVGMALLDRDDPTRVTHRGDEWVLEASEPYETGRSPTRSVTPSGAVIDVESRALRLYYGVADSGVCLATADLDEVLTYLLNQPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVR4</accession>
    <name>D3PVR4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018749.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3515"/>
    <dbReference type="EnsemblBacteria" id="ADD43178">
        <property type="protein sequence ID" value="ADD43178"/>
        <property type="gene ID" value="Snas_3515"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3515"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_425723_0_0_11"/>
    <dbReference type="OMA" id="NDERVDD"/>
    <dbReference type="OrthoDB" id="1382378at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048023" evidence="1">
        <location>
            <begin position="25"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="646" mass="68677" checksum="CFF64A242A5F6389" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW44</accession>
    <name>D3PW44_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">msrA</name>
        <name evidence="6" type="ordered locus">Snas_1497</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1497"/>
    <dbReference type="EnsemblBacteria" id="ADD41201">
        <property type="protein sequence ID" value="ADD41201"/>
        <property type="gene ID" value="Snas_1497"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1497"/>
    <dbReference type="eggNOG" id="COG0225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031040_10_0_11"/>
    <dbReference type="OMA" id="AGPFYYA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="5">
        <location>
            <begin position="24"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="191" mass="20901" checksum="9F4CD9C7E55F7C1C" modified="2010-04-20" version="1">MSDNVHTVLNTAIDGPVPAGHEVAVFGMGCFWGAERLFWRLDGVYTTSVGYSGGSDSPPSYEMVCTGTTGHAEVVQVVYDPAKVSYETLLKTFWENHDPTQGNRQGNDIGTQYRSVIYTTSEQQLKTAEESREAFQPVVTAAGLGPITTEIQPLPNYFLAEDYHQQYLDKNPNGYCNHGPNGMSCPIGVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW72</accession>
    <name>D3PW72_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016800.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1525"/>
    <dbReference type="EnsemblBacteria" id="ADD41229">
        <property type="protein sequence ID" value="ADD41229"/>
        <property type="gene ID" value="Snas_1525"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1525"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_2_5_11"/>
    <dbReference type="OMA" id="SYAVITE"/>
    <dbReference type="OrthoDB" id="1681849at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="156" mass="17223" checksum="FCBE232EBA2208A8" modified="2010-04-20" version="1">MKATELLADPRLTTMGLLFEAHEGLVAKLQPTWSKGGLSGLDLNALLRLSRSTGQRLRMSDLAAQTKLSTSGVTRLVDRLERLGLARRESFPGDRRTTYAVLTDAGSQRIEQVLPDYLAAIERWFTGLLSPEQLDALVAGLRVIRDAVHPDAERQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWC7</accession>
    <name>D3PWC7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ion transport 2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_1581</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016855.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1581"/>
    <dbReference type="EnsemblBacteria" id="ADD41284">
        <property type="protein sequence ID" value="ADD41284"/>
        <property type="gene ID" value="Snas_1581"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1581"/>
    <dbReference type="eggNOG" id="COG1226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011722_6_3_11"/>
    <dbReference type="OMA" id="ANIAAWF"/>
    <dbReference type="OrthoDB" id="1991946at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="PTHR11537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans_2" evidence="10">
        <location>
            <begin position="136"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="224"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD41284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="262" mass="29430" checksum="4BBBBC2A74A97E45" modified="2010-04-20" version="1">MFTKNSTARDERLPRVSAWERVSDLPLTILAIVFLLAYAIPIIFPDIPRRWHTILDYVDLAVWALFTVDYVRRLVIAEEKWYFVRTHLLDLAVVVLPPLRPLRLVRSAALLFSVVDRRTRAHPRRKMAILVGTTAVILLFLSALAALDAERGNPDAQIQSFGDALWWAIVTVSTVGYGDYFPVTVEGRLVAMTLMFGGVGLIGFITASVTSWVVEKLSKADKVADDTHDNVDLLLREVRQLRDEVAELRAEVGRRMPPASPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWD4</accession>
    <name>D3PWD4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016862.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1588"/>
    <dbReference type="EnsemblBacteria" id="ADD41291">
        <property type="protein sequence ID" value="ADD41291"/>
        <property type="gene ID" value="Snas_1588"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1588"/>
    <dbReference type="eggNOG" id="ENOG5030PG3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1569735_0_0_11"/>
    <dbReference type="OrthoDB" id="2011443at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="170" mass="18906" checksum="16FCAA15E23EC8E4" modified="2010-04-20" version="1">MSAVTRFKPTPMQLVALAFGPVALALGVYGVFRLVGVAVAIWQLWLLFFAIFAAFVVTASLRGGDDRLPRSRVVKPQVADRRPFAAAVRWEDRLGWSDTDAERFNNTVRKRIVPVVAERLWLAHRVDFHADPDRARALLPEQLFGLVTAPVSAPLTESEMDVIVSQIEAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-04-07" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWH1</accession>
    <name>D3PWH1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3531</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 26 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018764.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3531"/>
    <dbReference type="CAZy" id="GH26">
        <property type="family name" value="Glycoside Hydrolase Family 26"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43193">
        <property type="protein sequence ID" value="ADD43193"/>
        <property type="gene ID" value="Snas_3531"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3531"/>
    <dbReference type="eggNOG" id="COG4124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_782526_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006080">
        <property type="term" value="P:substituted mannan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022790">
        <property type="entry name" value="GH26_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000805">
        <property type="entry name" value="Glyco_hydro_26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40079">
        <property type="entry name" value="PTHR40079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02156">
        <property type="entry name" value="Glyco_hydro_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00739">
        <property type="entry name" value="GLHYDRLASE26"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51764">
        <property type="entry name" value="GH26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH26" evidence="5">
        <location>
            <begin position="1"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="313" mass="35209" checksum="1D82E88B11703EA7" modified="2010-04-20" version="1">MRDSADNRVLIGQEISSWSADTYDTFVHGLERKTGKRPAVVGLSLLEPGDYDTGGVDCLIDHHQRGGLVTVSTHWTHPWGDHPDTDKYRVIDDHAPKPDLRELLSGAPDSAPKRKYWEQVDDLTRVLTRLDKEGALVLLRPFHEMNGLWFWWGHDETTDHTALIDLWRDLHAHLSAKLSNLLWVYSPAASWNAGIAKYYPGADYVDLAGIDVYADDLRPYDPQHRPEDDDWTELSRLGHPAGLAEFGPAADSFPDGAATLTTRLADTYTKAVFAHAWTSWAEGQQRALVEQPDIDKALDDPAILTLDEVDWQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWQ8</accession>
    <name>D3PWQ8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018851.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3620"/>
    <dbReference type="EnsemblBacteria" id="ADD43280">
        <property type="protein sequence ID" value="ADD43280"/>
        <property type="gene ID" value="Snas_3620"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3620"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="AFVCYDD"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="5">
        <location>
            <begin position="4"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="342" mass="37166" checksum="258442409222D011" modified="2010-04-20" version="1">MANMKDVAKLAGVSVSTVSHIINGTRFVKEDTKNRVMDAIRQTGYIHNTIARSLVTSSTQTIGLAISAISNFYFADIIAAIERSARASGHTLLLADTHDDLDEELRVVQALHQRRVDGVLLATAGDADSESLQYLQDLGVPTVLVDRCASTKFDQVGTENIEATAELTGHLTEHGHQRIGLIAGRELLRTTVERERGWRLGLQRANLKPDRRLVASGQSSADFAEAAVERLLSEPDPPTALVVANNHMTIGVMSALTRLGVSVPDDLALAVFDDFEWANYFHPRLTAMAQPIGDIGACAIETLLSRIADPKRPTTTVQLPATFKRRESCGCQAPTRPAKEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWU1</accession>
    <name>D3PWU1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5534</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020736.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45165">
        <property type="protein sequence ID" value="ADD45165"/>
        <property type="gene ID" value="Snas_5534"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5534"/>
    <dbReference type="eggNOG" id="COG2013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040551_4_1_11"/>
    <dbReference type="OMA" id="ICQKDAF"/>
    <dbReference type="OrthoDB" id="1063432at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="SSF51219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00266">
        <property type="entry name" value="TIGR00266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="228" mass="24384" checksum="6818795330B07E4A" modified="2010-04-20" version="1">MKSDVRHPGSFAVVRCHLEAGEQIRVEAGAMLATSHGVALAAKVEGGLMRGLARKMLTDENLYTTTYTAPEFGGWVDLAHSLPGDVAVVPVRPEAALMIAKGSWIASNGEVEIQTKWGGMKNLIGGEGAFLVRAQGQGQLVLGCYGAIDSYALDPGETIVIDNGHVVAYEETVGHSLRRAVEGKTMQSRKSGEGLVYEFTGPGRVLTQSRNPEALIDYLTDVLPFEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWW6</accession>
    <name>D3PWW6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020761.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5559"/>
    <dbReference type="EnsemblBacteria" id="ADD45190">
        <property type="protein sequence ID" value="ADD45190"/>
        <property type="gene ID" value="Snas_5559"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5559"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_0_11"/>
    <dbReference type="OMA" id="YWANDSV"/>
    <dbReference type="OrthoDB" id="968232at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="240" mass="25129" checksum="165BB6712D391446" modified="2010-04-20" version="1">MISTVSLVTGGNRGIGREVCRQLAERGHTVVLTARSDDKAERAATELGVDWLALDVTDAASVAAAVATVTDRYGRLDVLVNNAAIHYDTWQRGITADLAVVREAAETNLYGPWLLIEEFLPLLRAGAHSRIVNVSSGSGSLNEMGAGTPAYSVSKAALNALTRIVAAELRGDGVLVNAVCPGWVATDMGGSGGRPVADGADGIVWAATLPDDGPTGGFFRDRRAIAWLASRNAVRPPGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWZ8</accession>
    <name>D3PWZ8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020793.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5592"/>
    <dbReference type="EnsemblBacteria" id="ADD45222">
        <property type="protein sequence ID" value="ADD45222"/>
        <property type="gene ID" value="Snas_5592"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5592"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_14_2_11"/>
    <dbReference type="OMA" id="ISINFRA"/>
    <dbReference type="OrthoDB" id="867226at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="7"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="524" mass="57033" checksum="DAF92F33DCE242E8" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX41</accession>
    <name>D3PX41_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020836.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5635"/>
    <dbReference type="EnsemblBacteria" id="ADD45265">
        <property type="protein sequence ID" value="ADD45265"/>
        <property type="gene ID" value="Snas_5635"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5635"/>
    <dbReference type="eggNOG" id="COG2188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063236_2_3_11"/>
    <dbReference type="OMA" id="PMLLLHR"/>
    <dbReference type="OrthoDB" id="1775418at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="15"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="248" mass="27768" checksum="62B89F1DDBF199A4" modified="2010-04-20" version="1">MLESGQVRRGVPEHGRVPKYFAVKARLVTLIGEIGEGEMLPPERELAARFEVSRATVRQAISELILEGRLAARQGRGTYVAPPKTIHPLELVSYTEAVASMGRRPGRRVVSAERIDASDELAERLRIGKRAKVIHLERVLLTDEEPTGLESTYLPAARFPRLLEVFDPAASLYRCLQDELGVVFDEADERIETALASPREALLLETNPAQPMLLLHRVSYDPQGVPIELVRTLYRGDRIGFSTRLRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX65</accession>
    <name>D3PX65_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyrrolo-quinoline quinone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1625"/>
    <dbReference type="EnsemblBacteria" id="ADD41328">
        <property type="protein sequence ID" value="ADD41328"/>
        <property type="gene ID" value="Snas_1625"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1625"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_623900_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048436" evidence="1">
        <location>
            <begin position="22"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="434" mass="46574" checksum="048F1B5042B5C62A" modified="2010-04-20" version="1">MRSRLSVGLCGVLVAAGVVVAGCSGGPEESPIRFENPPLWTHKDVNLDSVEGAALRGDAAILIGEWGNDARLVVADVATGDTRWSIAGEQELPGGDGLLITDAVPSPFGGVDKAPVIIDDGGDWAVVVAYNKFDEDNEDHRPDEQGVAALSGADGSMLWSAPLLKRGDTDEAETPRVYPITADGDTVLAATSGGAQAFALDAATGDKRWQQDKVWPHAVTDGVVVGQESLDREYPPWHGDSPRGGDVRAWDIESGEQKWKVKDKDKGDGLGHAMVANASMTLVSMTDSDVDTDDHVEVRDTRTGKKLATLDDGSPDCAFDSAKTTRFVCATSRAARFTTVSRSGGEATVTTIQVTEETDDFKIMSMYDGHIFVDTVASNRIYKDRYILDAEAQIVAKDLPGRPMAMTKKYAVFQTEDEETDEYRKAGIYKVVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXM3</accession>
    <name>D3PXM3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3696</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018924.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3696"/>
    <dbReference type="EnsemblBacteria" id="ADD43353">
        <property type="protein sequence ID" value="ADD43353"/>
        <property type="gene ID" value="Snas_3696"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3696"/>
    <dbReference type="eggNOG" id="COG2182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_498661_0_0_11"/>
    <dbReference type="OrthoDB" id="1520490at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015144">
        <property type="term" value="F:carbohydrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006060">
        <property type="entry name" value="Maltose/Cyclodextrin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00181">
        <property type="entry name" value="MALTOSEBP"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="546" mass="59705" checksum="77DF8BFB5F10159D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXM6</accession>
    <name>D3PXM6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3699</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018927.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3699"/>
    <dbReference type="EnsemblBacteria" id="ADD43356">
        <property type="protein sequence ID" value="ADD43356"/>
        <property type="gene ID" value="Snas_3699"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3699"/>
    <dbReference type="eggNOG" id="COG1129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_92_3_11"/>
    <dbReference type="OMA" id="RIDHKAT"/>
    <dbReference type="OrthoDB" id="551294at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="16"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="260"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="510" mass="55413" checksum="11AD0F42DF1ECE3D" modified="2010-04-20" version="1">MTTRPPGDPHDEPPLLELRDVSKTFGSIVALKSARLRVERGSIHALVGENGAGKSTLVKIVAGLHQRDDGSFRLDGEAVDFSSTAQSKAAGIAVIYQEPTLFPDLSVMENIFMGRQPLTRWRRVDRAAMRRRTRDLFQRLGVAIDPDRPAMGLSIADQQIIEIAKAISLDARLLIMDEPTAALSGIEVDRLFTIARALRDEGRGLVFISHRFNEIFDLCDRITVMRDGSYVATHDAADVTAAEVVNLMVGRPVETLYPKTEGGDVGEVVLRVDGLSRRGTFTDVSLTVRSGEIVGMAGLVGAGRSEVARAVFGVDDYDSGAVTVAGTPLRRGNPRAAIRAGLAFVPEDRRREGLLVEESVGRNIALVLRRKLANWGLIRRRDEDALAAGWARTLQITARDLDVAAGTLSGGNQQKAVIAKWMATDPRVLIIDEPTRGIDVGTKTEVHRLLDELAGRGLAILMISSDLPEILGMSDRVYVMSEGRITRELARDEATGEAVMTAATTLEAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXN3</accession>
    <name>D3PXN3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">L-lactate dehydrogenase (Cytochrome)</fullName>
            <ecNumber evidence="7">1.1.2.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3706</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.3" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018934.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3706"/>
    <dbReference type="EnsemblBacteria" id="ADD43363">
        <property type="protein sequence ID" value="ADD43363"/>
        <property type="gene ID" value="Snas_3706"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3706"/>
    <dbReference type="eggNOG" id="COG1304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020639_0_0_11"/>
    <dbReference type="OMA" id="FTRLMQT"/>
    <dbReference type="OrthoDB" id="1186741at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004460">
        <property type="term" value="F:L-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02809">
        <property type="entry name" value="alpha_hydroxyacid_oxid_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="2 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="6">
        <location>
            <begin position="27"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="106"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="353"/>
            <end position="354"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="409" mass="45204" checksum="AE455E2D5424C5F8" modified="2010-04-20" version="1">MRRRVPRPKELLPLLRFRKPRFSAARRRLESAVTIYDLREAARRRTPKAAFDYTDGAAEAELSLARARQAFEDIEFNPTILRDVSSVDTGWEVLGERVALPFGIAPTGFTRLMQTEGEIAGATAAEAVGIPFALSTLATTSIEDVKAASPNGRHWFQLYMWKDRDRSMALVERAAAAGYDTLMVTVDTPVAGARLRDKRNGFSIPPQLTLKTMLNTATRPAWWFNLLTTEPLSFASLDRWPGTVAELLDTMFDPTVDFDDLAWIKQQWPGKIVVKGVQNLADAKRLADLGVDGVVLSNHGGRQLDRAPVPFHLLPTVVREVGADMEVHVDTGIMSGADIVASVALGARFTLVGRAYLYGLMAGGRRGVDKTIEILSEQVVRTMRLLGVSSLEELEPAHVTQLRRLTPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXZ3</accession>
    <name>D3PXZ3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5692</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5692"/>
    <dbReference type="EnsemblBacteria" id="ADD45322">
        <property type="protein sequence ID" value="ADD45322"/>
        <property type="gene ID" value="Snas_5692"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5692"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_9_0_11"/>
    <dbReference type="OMA" id="DSARMMD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014298">
        <property type="entry name" value="RNA_pol_sigma-X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02952">
        <property type="entry name" value="Sig70_famx2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="103"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="206"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="36"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="266" mass="29740" checksum="EA711C9BE61048AB" modified="2010-04-20" version="1">MPGTVPVVTAGTVTPQFQASRQTLRDGLTSLRQMLTVDLNPSRVEAPSPASDGDREEPSCNSGEDDSGQPDSQSCSAEVGPAEVRELVARAQDGDVDAFGRIYDRYNEIVHRYIYFRVGNRQLAEDLTSEVFLRALRRISTFTWQGRDFGAWLVTIARNLVADHFKSGRYRLEMSTAEVLDIDREERAPEGNPEDTVCDKLLNVTLLKAVRELNPDQRECIVLRFLQGMSVAETAGYMRKNEGAIKALQYRAVRTLARLLPEGFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY58</accession>
    <name>D3PY58_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5757</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5757"/>
    <dbReference type="EnsemblBacteria" id="ADD45387">
        <property type="protein sequence ID" value="ADD45387"/>
        <property type="gene ID" value="Snas_5757"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5757"/>
    <dbReference type="eggNOG" id="ENOG502Z8QX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071594_0_0_11"/>
    <dbReference type="OMA" id="WQLPVRR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="268" mass="29598" checksum="221C385F09BCDC2E" modified="2010-04-20" version="1">MRDTEETGLDFPREWIEFPDPDDSDTIVRADLTWLLSRWTCIFGQGCPGIDAENPDDGCCVHGAFFTEADDEERVRKAAAKLTPETWQNYRADYADVVVDDTLADDDGVEQPARKTATVDGACVFHNRPGFSGGMGCALHAQALRDGVHPLKYKPEVCWQVPVKRDYSTVERADGSVAEITWIGEFDRRAWGAGGHDFDWWCASAPSAHVGAQPVYRSYEAELIELIGKGAYAKLAELCAERERIGQLAVHPATRKALPLTVAPRPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY75</accession>
    <name>D3PY75_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amidase, hydantoinase/carbamoylase family</fullName>
            <ecNumber evidence="4">3.5.1.87</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5774</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20 family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.87" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5774"/>
    <dbReference type="EnsemblBacteria" id="ADD45404">
        <property type="protein sequence ID" value="ADD45404"/>
        <property type="gene ID" value="Snas_5774"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5774"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024588_6_0_11"/>
    <dbReference type="OMA" id="IWPHGRW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050538">
        <property type="term" value="F:N-carbamoyl-L-amino-acid hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010158">
        <property type="entry name" value="Amidase_Cbmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494">
        <property type="entry name" value="PTHR32494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001235">
        <property type="entry name" value="Amidase_carbamoylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01879">
        <property type="entry name" value="hydantase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>allantoate</name>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>allantoate</name>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>allantoate</name>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001235-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001235-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="399" mass="42081" checksum="F344D5D37A1F4F0B" modified="2010-04-20" version="1">MWFEEMWRELAPIGRFDGTGGYRRFTYTPAELECRAWFTAQATSRGLSVETDRNGNLWAWWGDADAGGAIATGSHLDSVPDGGAFDGPLGIVSAFAAIDLLRQAGFTPGKPIAVAAFAEEEGARFGVACLGSRLLSGAITPEAARALTDDNGVTLADAMATIGADPDAIGRDERLLSRIDAYVELHIEQGRAQVDMDAPVAVAEAIWPHGRWRMDFTGRADHAGTTRLEDRADPMLTYANTVLAARKKARLAGAVATVGRIVCEPNGTNAIPSRVRAWLDARAPELAALEQVVTELEQATVERAGRDGTSVTVSRESYSPHVAFDVPLRDRLAGVLGGAPLLATGAGHDAGVLAASIPTAMLFVRNPTGVSHSPAENAEMPDCLAGADALATVLRELAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYM5</accession>
    <name>D3PYM5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4HBT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3802</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019029.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43458">
        <property type="protein sequence ID" value="ADD43458"/>
        <property type="gene ID" value="Snas_3802"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3802"/>
    <dbReference type="eggNOG" id="COG5496">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119426_0_1_11"/>
    <dbReference type="OMA" id="GIMECAC"/>
    <dbReference type="OrthoDB" id="1895484at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025540">
        <property type="entry name" value="FlK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36934">
        <property type="entry name" value="PTHR36934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014972">
        <property type="entry name" value="FlK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="3">
        <location>
            <begin position="44"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR014972-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR014972-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="141" mass="15199" checksum="688DDDCA002296BF" modified="2010-04-20" version="1">MTEIALTPGLRHSARLTVDESLTVPAVNPSFTGFADMPRVLATAFLVAFVESTCVEALSPLLPSGTQTVGTLVNISHTAATPVGLTVTATVELIEVDKRRLRFAVECRDDRDVIGKGHHERFIIDRRAFDASAEAKRANPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYU6</accession>
    <name>D3PYU6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3874</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3874"/>
    <dbReference type="EnsemblBacteria" id="ADD43529">
        <property type="protein sequence ID" value="ADD43529"/>
        <property type="gene ID" value="Snas_3874"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3874"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="ALGSANC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="935" mass="102010" checksum="3404423EE615B257" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYW4</accession>
    <name>D3PYW4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019118.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3892"/>
    <dbReference type="EnsemblBacteria" id="ADD43547">
        <property type="protein sequence ID" value="ADD43547"/>
        <property type="gene ID" value="Snas_3892"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3892"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_1_0_11"/>
    <dbReference type="OMA" id="MTGWMGP"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="3"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="396" mass="43603" checksum="84DAC239618D2F8E" modified="2010-04-20" version="1">MKAVICGAGIAGLALAQRLASIDWEVVVVEKAPGPREQGYMIDFFGPGLRAATAMGIEPRLRELGYKVREFSYLDETGRKRASLDYQRFSRVADGLLSIMRPDLERTLREALPATVDLRFATTITAIHNRPDGVTVTLSDGQTLEADLLVGADGIHSRTRAMVFGPEERYLRHLGLHTAAFTFTDPEIHAEVRDGFYLTDTVAKEMGMYGMRDGKVSVFTVHRTDSRKLPDDPRAVIRETYADLGWRVPRALELCPPPSHVYYDLVAQIHMPNWVDKRVVLVGDACYAVSLLAGQGASLGIAGAHILAGQLRTGTVDEALARYQRLWHPIATERQRIGRNGAKWIVPTTPTQLWLRRLAIKAMGIPGLDRYLGSALVGKDHTDVDALAVAEEPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ65</accession>
    <name>D3PZ65_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5865"/>
    <dbReference type="EnsemblBacteria" id="ADD45494">
        <property type="protein sequence ID" value="ADD45494"/>
        <property type="gene ID" value="Snas_5865"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5865"/>
    <dbReference type="eggNOG" id="ENOG5033B4F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104210_1_1_11"/>
    <dbReference type="OMA" id="GWWSATH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021202">
        <property type="entry name" value="Rv3654c-like"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03816">
        <property type="entry name" value="tadE_like_DECH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="127" mass="12869" checksum="7A5BD5E8F328DB24" modified="2010-04-20" version="1">MTIRRRETTPARQRDPQRGGASVIALGIGLCVLVLAMVALLMAAAIEARHRAQIGADAAALAGAMRAGQGATSACGRAAELAAANDTTIRTCELSGMDITVEVIAPLPSPLKRFGPVVGLARAGPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZP0</accession>
    <name>D3PZP0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3922</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3922"/>
    <dbReference type="EnsemblBacteria" id="ADD43577">
        <property type="protein sequence ID" value="ADD43577"/>
        <property type="gene ID" value="Snas_3922"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3922"/>
    <dbReference type="eggNOG" id="COG1721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052321_0_0_11"/>
    <dbReference type="OMA" id="HVREHHA"/>
    <dbReference type="OrthoDB" id="848990at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="DUF58" evidence="3">
        <location>
            <begin position="223"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="459" mass="50624" checksum="11E00AB894DB9E78" modified="2010-04-20" version="1">MSLGAMGHLSDRVRSASYEHPRSTPFAPRTETDWNPTPALRRALIVVIVALGLGLILGRVDLLLVSMPLALGLAASLTRRPRRSPELRLLGMPETPLLEGGELRAEIEVSNPDEVEIVAVARPRVSQWIRLSHGGFRQAAVVPADGHASLPLTAVTRRWGLHRFGPIEVRALACDGLLRSRQLSVAKQTLTVYPRAALFDSRQSLPRAAGLAGVHHTRRPGDGGELAEVRRFQPGDRLRSIDWRVSLRQRELHVNATYSERDADVLILLDVLSEVGQPGQASSLDVTVRAAAAIAEHYTSQGDRVAMAEFGSKNRRLRAGGGRRHYALVQDWLTHVDPSRGEIRAAAERQLVSRKLPGSAAIIMLTPLLDPRSTSGLARLAQTGRPLVAVDTLPPGVRPTQQREWTQLAFRLWHLERDNTLNRLRALGVPVERWMGPGSLDHMLRQVALLDHVPKLARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZP8</accession>
    <name>D3PZP8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019156.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3931"/>
    <dbReference type="EnsemblBacteria" id="ADD43585">
        <property type="protein sequence ID" value="ADD43585"/>
        <property type="gene ID" value="Snas_3931"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3931"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1026395_0_0_11"/>
    <dbReference type="OMA" id="VVCECAF"/>
    <dbReference type="OrthoDB" id="1518440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="53"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="271" mass="29725" checksum="3CA9FB1AF0296B15" modified="2010-04-20" version="1">MTDPQFLARSYEAYAEVEAEFNDALDVSLDPCGPGMLFDLVAEIGLPAGARALDVGCGEGGHAFELADRFGLRVHGVDPVPRHIDIAKSQARPESTAAVTFEAGTAQALPVADASVDLVWCRDTLCHVEDLDAAYAEFRRVLKPDGTALVYQMFATDTLEPNEAAWLFSTMGCIPSSMDPTRSEAAMMASGLSIERRLVLGTQWGERGQETTGKGGRKLLHAARLLREPERYVSRYGRSNYDIALGDCLWHVYRLIGKLSDRVYRLRRPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZQ7</accession>
    <name>D3PZQ7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3941</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019165.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3941"/>
    <dbReference type="EnsemblBacteria" id="ADD43594">
        <property type="protein sequence ID" value="ADD43594"/>
        <property type="gene ID" value="Snas_3941"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3941"/>
    <dbReference type="eggNOG" id="COG1361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_608206_0_0_11"/>
    <dbReference type="OrthoDB" id="1946at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049597" description="DUF11 domain-containing protein" evidence="2">
        <location>
            <begin position="35"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="3">
        <location>
            <begin position="273"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="450" mass="45711" checksum="ECA31196EF1A29C8" modified="2010-04-20" version="1">MKLFRHTRLTITAVAVTAIAISTSIGVTGTGADAAITDSGLASRFSADLYGDVTTIGNREPACGHDCAEASSARLRIPEGATVAHARLSWASGLGEACRTDAPTASTRLRVGDAEAATVPGRVTGGDTAEADVTKRLSGLAGGTAVTVEGVRAGDCAAGWSLTVAYELPRGRADGVVKRHVAIYGGALTASESALRLDGFRRFGTAAPRLSATGYGDTRLSVNGTAIAPAGSHITDTPLPEGVIAAGDTSADIGISGAEPLLQQVALSVPVPDVSINATATPQRIGPGDTVVHTITVTNNGDAPVEDASFRVDLSRALDDATRPFDVTASTGESVFKGRSLKWTGTLPAEATATLTYSVTVKNPRPGDGKLESTVIGGTDTNCSAKKPASECFVKLSFPPRPKVDVNDSGTGIFLPVTGAPVGGLFALATVALLGGAALWLASRRPGRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZR8</accession>
    <name>D3PZR8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lysine 2,3-aminomutase</fullName>
            <ecNumber evidence="1">5.4.3.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3953</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.4.3.2" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019176.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3953"/>
    <dbReference type="EnsemblBacteria" id="ADD43605">
        <property type="protein sequence ID" value="ADD43605"/>
        <property type="gene ID" value="Snas_3953"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3953"/>
    <dbReference type="eggNOG" id="COG1509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032161_1_1_11"/>
    <dbReference type="OMA" id="GFMMPSF"/>
    <dbReference type="OrthoDB" id="557227at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050066">
        <property type="term" value="F:lysine 2,3-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003739">
        <property type="entry name" value="Lys_aminomutase/Glu_NH3_mut"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30538">
        <property type="entry name" value="PTHR30538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="475" mass="53652" checksum="1472D426C1CAD3A0" modified="2010-04-20" version="1">MSHQLTGQPYEYKRTPLVEPDWRRFPGWAEVTEEEWSSAQWQRVHCVKNVAQLRGVLGDRVDDAFYDDLAADGDKRATMSMLLPPQMLNTIAPTLETTAPGSWTEAYYADPIRRYMLPVFSDRRTDWPSHPHATRDSLHEHDMWVAEGLTHRYPTKVLAELLSTCPQYCGHCTRMDLVGNSTPTIDKLKLKLKPMARYDAMIEYLQSHPGVRDVVVSGGDVANVPWKNLENFISRLLEIESIRDIRLATKALMGLPQHWLQDDVVDGMGRVATVARERGVNLAIHTHVNHVQSLTPTVARAARAMLDAGVRDVRNQGVLMNGVNNSPEALLDLCFALQGEANILPYYFYMCDMIPNSEHWRTSVSEAQALQTAIMGYLPGYATPRIICDVPFVGKRWVHQVGRYDAEHGISYWTKNYRTSIEAADPDALTREYPYYDPIHTLPEAGQAWWRDQFPPSQIAEAGHAAAALSRAASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZY6</accession>
    <name>D3PZY6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4021</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019244.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4021"/>
    <dbReference type="EnsemblBacteria" id="ADD43673">
        <property type="protein sequence ID" value="ADD43673"/>
        <property type="gene ID" value="Snas_4021"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4021"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_11"/>
    <dbReference type="OMA" id="WQQSYGD"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="127"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="127"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="235" mass="25485" checksum="1E8912EF6B539C07" modified="2010-04-20" version="1">MATVLLIEDDANVSAALTRALSKAGHHVRAESTALEALRKVTADPPDVVILDLGLPDLDGADALRMLRGVSNVPVIIASARRGETDIIKLLNAGADDYVTKPFSAAHLLARIAAVLRRHESSDTAKSVLITVGPLSVDQSRHVAALDGNELELTRREFSLLTYLARHAGRVVSKQELVEQVWRQPYIGAEATVDVHVSWLRRKLGETAAKPRLLRTVRGVGIMLSDEPVTQPGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q035</accession>
    <name>D3Q035_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5937</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021135.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5937"/>
    <dbReference type="EnsemblBacteria" id="ADD45564">
        <property type="protein sequence ID" value="ADD45564"/>
        <property type="gene ID" value="Snas_5937"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5937"/>
    <dbReference type="HOGENOM" id="CLU_833965_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="374" mass="39815" checksum="237DCC08813C8810" modified="2010-04-20" version="1">MSSPPHDTDADIDGPAPDGEAPPSHLSGFTVEQGFSVIPPKRPRTVTAAAAMMFVYAGLAVPPGLALFVTTLDDLSSGPLFTLFRDAGQLLFAAAVAVGFAVVPVLVLRGRDPARVSAFVLTGAVAFVAVSIVVRGFAGRLLSVPGGEDFLVVIIATAVLAAVVVTTVLLAGNRADAWFYEARGERFINRDTGPPTRPRGVVVATVALGVIALTELIELTIQIVDAFSTDTNYSNPTSQIVYMVPDSLPILAVTLVAMVLVFFTYETARVLAFGLCGAIGVYFLSGIFDLATVLTSDFYSGIDGLYYVRRSLLLFQVVASVFVVTGLAGKPTAAWFRLWRDVRAEREVWRADDLTILAAGSPSPSDRRRDSDWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0H7</accession>
    <name>D3Q0H7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2018"/>
    <dbReference type="EnsemblBacteria" id="ADD41713">
        <property type="protein sequence ID" value="ADD41713"/>
        <property type="gene ID" value="Snas_2018"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2018"/>
    <dbReference type="HOGENOM" id="CLU_1947513_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="129" mass="13889" checksum="75CF6F6970116920" modified="2010-04-20" version="1">MENLREVATVYLPRMANDYTGLTSSLRQTTGTDGAFDRSGEFGAQEFKAAWTALRDLIWTSSDQTSDNLYALGVGLKSAVDEFCANDEAAAAAMDAERATFEGKNGPSGLEWNQPYGNDENAPPLVVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0P1</accession>
    <name>D3Q0P1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YCII-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2083</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017348.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2083"/>
    <dbReference type="EnsemblBacteria" id="ADD41777">
        <property type="protein sequence ID" value="ADD41777"/>
        <property type="gene ID" value="Snas_2083"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2083"/>
    <dbReference type="eggNOG" id="COG2350">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1494754_0_0_11"/>
    <dbReference type="OMA" id="QSHTIGF"/>
    <dbReference type="OrthoDB" id="1780176at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="188" mass="20719" checksum="85E00708406B2057" modified="2010-04-20" version="1">MPFYVHAKDKPGVGAELDKLVEEHWSYMDRFDERLILRGPTLSDDGEEHTGSVHIVDLDDRAAADRFGDEEPFWQAGLYEDITTERAAVLLDREPSAASRSGEAPNALLVGRWEPKPHNAPTLGADTDARLDFVALLVDDDQSHTIGFVAVVTAMPDEAEAIARPLADRFAGEAVPLAVTRWCRGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0R7</accession>
    <name>D3Q0R7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2109</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017374.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2109"/>
    <dbReference type="EnsemblBacteria" id="ADD41803">
        <property type="protein sequence ID" value="ADD41803"/>
        <property type="gene ID" value="Snas_2109"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2109"/>
    <dbReference type="eggNOG" id="ENOG5032SM3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116291_0_0_11"/>
    <dbReference type="OMA" id="WANEFSD"/>
    <dbReference type="OrthoDB" id="1884713at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021903">
        <property type="entry name" value="DUF3515"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12028">
        <property type="entry name" value="DUF3515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="204" mass="21816" checksum="3EE6084FE36BFB50" modified="2010-04-20" version="1">MAEDEKPAVSAKSRDEKATASRQERRRAARIATLVAIPVTLVALFGAISFMGSMAGAEEESSDVPDEAVEVAAPDLSDEDFKYCRALITKLPDPLGDLKRRVVSGDNGAPEIAGAWGDPAAKLRCGVEPVKVAKDAKVYRLGPTCWFADKSKKTTTWTTVDRELAVELTVPNKYEQPGQLAQALSKPVDKKIPASKDAPTGCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0T3</accession>
    <name>D3Q0T3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SMC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019254.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4031"/>
    <dbReference type="EnsemblBacteria" id="ADD43683">
        <property type="protein sequence ID" value="ADD43683"/>
        <property type="gene ID" value="Snas_4031"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4031"/>
    <dbReference type="eggNOG" id="COG0419">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004785_1_2_11"/>
    <dbReference type="OMA" id="HACPVCE"/>
    <dbReference type="OrthoDB" id="1143316at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="2">
        <location>
            <begin position="5"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="245"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="810" mass="87162" checksum="8CA74C15E3FD5D55" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0U5</accession>
    <name>D3Q0U5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4043</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019266.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4043"/>
    <dbReference type="EnsemblBacteria" id="ADD43695">
        <property type="protein sequence ID" value="ADD43695"/>
        <property type="gene ID" value="Snas_4043"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4043"/>
    <dbReference type="eggNOG" id="ENOG502Z8YF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_860368_0_0_11"/>
    <dbReference type="OMA" id="FFDPFGW"/>
    <dbReference type="OrthoDB" id="528668at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="305" mass="32953" checksum="B6867994FD8FDC6F" modified="2010-04-20" version="1">MSLPYTGSGPYCYANSLSMMLGPETPGPSRLEVLTGSPFGMQLLGGKLPLFDPYGWDPDLGIDDALRLLGWRCERNVGGDADTAVAMLREAVKRGPVMVGPVEMGLLSHQPTMTGAIGADHWVVVLEVDDDVVVMHDPHGHPYATLPVAQFAKAWRAELVPWVDPPFVMRTDFVKERDVDVREALRAALPGAVRWLTNAYDGTVPPGTLGTEAALHRLAELTESGLDEETRGHLVHFAVRVGARRLNDAAVALSDIDQPAAARIAARQSRLVGRLQYDLVAGNNKSAAATMRRLAPTYFELAAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q103</accession>
    <name>D3Q103_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019324.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4102"/>
    <dbReference type="EnsemblBacteria" id="ADD43753">
        <property type="protein sequence ID" value="ADD43753"/>
        <property type="gene ID" value="Snas_4102"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4102"/>
    <dbReference type="eggNOG" id="ENOG50337PM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_173933_0_0_11"/>
    <dbReference type="OMA" id="LRGCPMC"/>
    <dbReference type="OrthoDB" id="1992259at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="94" mass="10130" checksum="68D0E211CC160C32" modified="2010-04-20" version="1">MTDNFASKSVPRHVLKGVVGFGTIIAAFALIPVLGWFSLALAPLGLLVLRGCPMCWTIGLLQTISAGRLRRECTDDGCQLKVADRPPAEHEANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q129</accession>
    <name>D3Q129_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome-c oxidase</fullName>
            <ecNumber evidence="3">7.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Cytochrome aa3 subunit 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ordered locus">Snas_4128</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4128"/>
    <dbReference type="EnsemblBacteria" id="ADD43779">
        <property type="protein sequence ID" value="ADD43779"/>
        <property type="gene ID" value="Snas_4128"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4128"/>
    <dbReference type="eggNOG" id="COG1622">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036876_3_0_11"/>
    <dbReference type="OMA" id="HAFMPIA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045187">
        <property type="entry name" value="CcO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001505">
        <property type="entry name" value="Copper_CuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014222">
        <property type="entry name" value="Cyt_c_oxidase_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036257">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22888">
        <property type="entry name" value="PTHR22888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00116">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81464">
        <property type="entry name" value="SSF81464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02866">
        <property type="entry name" value="CoxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00078">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0186">Copper</keyword>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="32"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_CUA" evidence="17">
        <location>
            <begin position="109"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="242"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ADD43779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="269" mass="30527" checksum="F472708C4350662E" modified="2010-04-20" version="1">MSLPLLAGCSVDEAFAFGWPRKLPTPESREMFNMWIGSTIAALAVGVFVWGLIFWCVIRYRKKSDELPVQTRYNLPMELLFTVTPFLIIAVLFYYTVIVQSNVTKLTENPDTEVTVTAFKWNWEFSYPEAEGKDGKPVSTVGDSDYVPVLVVPTNERIRFTEVSEDVIHSFWVPDLLFKRDVMPGYENKFEVTIEEEGAYVGRCAELCGAYHSMMNFEMRAVSGEDYKKFLKQLQAGKSTPEALEAIGEDPYATTTKPFDTKPNSRKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q150</accession>
    <name>D3Q150_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylglucosamine 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Enoylpyruvate transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylglucosamine enolpyruvyl transferase</fullName>
            <shortName evidence="7">EPT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murA</name>
        <name evidence="9" type="ordered locus">Snas_4149</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:18681"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="EC" id="2.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the EPSP synthase family. MurA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.7" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4149"/>
    <dbReference type="EnsemblBacteria" id="ADD43800">
        <property type="protein sequence ID" value="ADD43800"/>
        <property type="gene ID" value="Snas_4149"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4149"/>
    <dbReference type="eggNOG" id="COG0766">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027387_0_0_11"/>
    <dbReference type="OMA" id="CRFGQRN"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008760">
        <property type="term" value="F:UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019277">
        <property type="term" value="P:UDP-N-acetylgalactosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01555">
        <property type="entry name" value="UdpNAET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00111">
        <property type="entry name" value="MurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005750">
        <property type="entry name" value="UDP_GlcNAc_COvinyl_MurA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01072">
        <property type="entry name" value="murA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="35"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate binding" evidence="7">
        <location>
            <begin position="50"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="2-(S-cysteinyl)pyruvic acid O-phosphothioketal" evidence="7">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD43800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="468" mass="50640" checksum="18E1341AAB2ECC9D" modified="2010-04-20" version="1">MKRPVLTYMLALGSAFHSRTSEGCALNDDDVLVVHGGTPLKGEIRVRGAKNLVSKAMVAALLADSPSTLFDVPAISDVDIVRGLLELHGVRTSIDKDRSLRMDPTNVVTAGVDEINVHAGSSRIPILLCGPLLHRLGSAYIPDLGGCNIGGRPIDFHIDALRKFGAVVEKLPDGMHLTAPQRLQGIKYTLDYPSVGSTEQILLTAVMAEGVTELRNAAVEPEIIDLICILQKMGAIIKVNTDRVIEIEGVDRLSGYRHRPVPDRIETGSWAAAALATHGEVFVRGARQVDMMTFLNVYRTIGGAFDVDDSPGGGIRFWHPGGELSPAALETDVHPGLMTDWQQPLVVALTQARGLSIVHETVYERRFGYTAELRQMGANIQLYRDCLGGTPCRWGRRNFLHSAVIAGPSKLHAADLQIPDLRAGFSHLIAALAAEGTSRVFGVDRFITRGYEDFDAKLAGLGANVERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q168</accession>
    <name>D3Q168_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021219.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6023"/>
    <dbReference type="EnsemblBacteria" id="ADD45648">
        <property type="protein sequence ID" value="ADD45648"/>
        <property type="gene ID" value="Snas_6023"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6023"/>
    <dbReference type="HOGENOM" id="CLU_2398170_0_0_11"/>
    <dbReference type="OrthoDB" id="1966197at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022062">
        <property type="entry name" value="DUF3618"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12277">
        <property type="entry name" value="DUF3618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="93" mass="10915" checksum="4612CC3DE6428E00" modified="2010-04-20" version="1">MVETPDRIRSDIESTRAELTHDVNRLADRVSPRRIARRRWHVLRDKLSLLYQELTGRIRTKPRKRVRGRQGDGSVVASRPDRGGEERTLPHRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q170</accession>
    <name>D3Q170_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021221.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6025"/>
    <dbReference type="EnsemblBacteria" id="ADD45650">
        <property type="protein sequence ID" value="ADD45650"/>
        <property type="gene ID" value="Snas_6025"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6025"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_13_0_11"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="460" mass="49336" checksum="FBA59F596BD44639" modified="2010-04-20" version="1">MSTNDVITTTRQRLDTLRAKHRIPGAQLAILVDGEIHELASGILNKNTGVAVTTDSVFQSGSVAKVYTATAAMRLVDQGRLDLDAKVVDVLPEFGTPDAEATARITVRHLFCHLSGTGSEFHGNPNRGDDCIELFVRDAREVPMDLPPGVAASYSNIGIITLARIVEVITGEVWDDALKQLLFEPLGLKRSFTLTEDAVRYNVAMGHLGAPGAEPEPAEMWTVHPRAASPAAHILMSAGDMARFAKLHLDGGVTADGTRIMSAESVAAMREPQSVPVDRWSVSADAWGLGWSLYDHPNYHGFGHDGSAVSQHAMLRIYPEQGVALALMTNSGAGRSLYADLFPELLASLGITMPAPFGPADPPIAADATRFYGTYEREGVTITVGEQDGVPRFRYEFTGTAAHVSPPLEGELKAVAGEGDNVFSVRFGAEGSDEDLAVIFATHNDTEYVWIGMRATPRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q183</accession>
    <name>D3Q183_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021234.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6039"/>
    <dbReference type="EnsemblBacteria" id="ADD45663">
        <property type="protein sequence ID" value="ADD45663"/>
        <property type="gene ID" value="Snas_6039"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6039"/>
    <dbReference type="eggNOG" id="COG1409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070320_2_1_11"/>
    <dbReference type="OMA" id="TGIGHMD"/>
    <dbReference type="OrthoDB" id="1242748at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004115">
        <property type="term" value="F:3',5'-cyclic-AMP phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="5"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="245" mass="26805" checksum="037733983543F1BB" modified="2010-04-20" version="1">MVLLAQISDLHLDGSERATQRAVRTMEYLRGLATPVDALLVTGDIADHAEVAEYEEAARLLKAPFPVLMCPGNHDARGPYREVLLGEAADEAPVNRVHRVGDIAVLMCDSTIPGRDDGELDERTREWIAATLTELGGTPALVAFHHPMVNMHHPFVDSLRLRNGEELAALLSGFENVVAILTGHTHTAAASSFAGLPLRMSPSVTYALRLPWEGDEITNWEQPPGVAFHVVDENRELITHFRSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1B5</accession>
    <name>D3Q1B5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6071"/>
    <dbReference type="EnsemblBacteria" id="ADD45695">
        <property type="protein sequence ID" value="ADD45695"/>
        <property type="gene ID" value="Snas_6071"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6071"/>
    <dbReference type="HOGENOM" id="CLU_3173446_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="47" mass="5670" checksum="D5756624FE4421A5" modified="2010-04-20" version="1">MNTFEKFRANRLRRAEAAHQRAIMRKRVESSTDLARRDAMLYSNRLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1H2</accession>
    <name>D3Q1H2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable 2-phosphosulfolactate phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_6128</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23416"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15597"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58738"/>
            <dbReference type="EC" id="3.1.3.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ComB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.71" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6128"/>
    <dbReference type="EnsemblBacteria" id="ADD45752">
        <property type="protein sequence ID" value="ADD45752"/>
        <property type="gene ID" value="Snas_6128"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6128"/>
    <dbReference type="eggNOG" id="COG2045">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094942_0_0_11"/>
    <dbReference type="OMA" id="FPWGEQA"/>
    <dbReference type="OrthoDB" id="1617556at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050532">
        <property type="term" value="F:2-phosphosulfolactate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005238">
        <property type="entry name" value="ComB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036702">
        <property type="entry name" value="ComB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04029">
        <property type="entry name" value="2-ph_phosp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142823">
        <property type="entry name" value="SSF142823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="279"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="305" mass="31838" checksum="AAB7838638995D25" modified="2010-04-20" version="1">MSDYFGQNGYSVRFGWGPMEAMELASEGACVVVVDVLSFTTAVTVAVEHGSAVFPYPWRDESARGFAAQHDAELAVGRRMVDTDNPWSLSPAALLAAPKVARLVLPSPNGSSIAASVRQGTVVAGCLRNATAVGKWIGGNGYGQPGRPVVVIAAGEKWGDGSLRPCLEDLLGAGAVLAALPVDDAHWSPEARAARAAFAGSTDVVRAVRDCGSGVELSRQGFASDVDVAVELAASTVVPVLTDGAFRAERPLRPRRRAGQRCGAGRGALRSWRRAPRRDHGVVLDDGPPSGRYGSDSGTAVWCST</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1L4</accession>
    <name>D3Q1L4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, CarD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015433.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0142"/>
    <dbReference type="EnsemblBacteria" id="ADD39862">
        <property type="protein sequence ID" value="ADD39862"/>
        <property type="gene ID" value="Snas_0142"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0142"/>
    <dbReference type="eggNOG" id="COG1329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048259_1_2_11"/>
    <dbReference type="OMA" id="DMKVMIP"/>
    <dbReference type="OrthoDB" id="1942592at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042215">
        <property type="entry name" value="CarD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CarD_TRCF" evidence="1">
        <location>
            <begin position="2"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="161" mass="17743" checksum="2AC5D4316FF29F76" modified="2010-04-20" version="1">MSFSVGETVVYPHHGAALIEAVETRTIKGVEQEYLVLRVEQGDLTVRVPAGNVELVGVREVVGAEGLTEVFDVLRAPHTEEPTNWSRRYKANLEKLASGNPLKVAEVVRDLWRRDRERGLSAGEKRMLTKARDILVGEVALAEASTKDDAEVLLDKVLAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1P4</accession>
    <name>D3Q1P4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0172</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015463.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0172"/>
    <dbReference type="EnsemblBacteria" id="ADD39892">
        <property type="protein sequence ID" value="ADD39892"/>
        <property type="gene ID" value="Snas_0172"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0172"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_3_11"/>
    <dbReference type="OMA" id="YFYIWAI"/>
    <dbReference type="OrthoDB" id="1619224at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="70"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="293" mass="32317" checksum="802428395CA0C133" modified="2010-04-20" version="1">MAATQVTEVAPRRRRIPPVVWLIAPSVLFMAALMGWPTISGLIQAFKTGDGFGFDNFARMAADPFFWPAVRNTLLLIVILIPVQFALALGMALLLRAKPKLSGLYFYIWAIPLAVSDLAAGLVWLSIFTDHGYLNSFLSHLGIDGVNWLSYDSNTSMFFAVFIAELWRATSLVLVIVVAGMQGIPKDYDEAAQVFGASYWQRLRHVTLPLLRPSLQVALILRTILAFQTFAVAQALTGRDFPVLVGETYNWYVALRNPSVASALALVILAISMITAIVYLRALRDPSDKGGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1S1</accession>
    <name>D3Q1S1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MDMPI_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015490.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0200"/>
    <dbReference type="EnsemblBacteria" id="ADD39919">
        <property type="protein sequence ID" value="ADD39919"/>
        <property type="gene ID" value="Snas_0200"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0200"/>
    <dbReference type="eggNOG" id="COG1576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051661_1_0_11"/>
    <dbReference type="OMA" id="CTEWSIR"/>
    <dbReference type="OrthoDB" id="1805421at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017520">
        <property type="entry name" value="CHP03086"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03086">
        <property type="entry name" value="TIGR03086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="1">
        <location>
            <begin position="8"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="196" mass="21244" checksum="5FE60F4C4886DE79" modified="2010-04-20" version="1">METMTAYRRAQDGFDQVMAAVGDEQWDRPSTCAEWTIRDVAGHVIWGQRQLRAWAVGEEYESPTGFPGSSKPGELAADDPLATWRTARAAADEALTDETLARVVTIGGPVGDIPVIGVAELLTTDLLGHSWDIGHAAGQDVRLDAELLPGSMEWSRKYVSRSAALFGPEVTPEADADDQDRLLAYLGRRPGQHLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1W5</accession>
    <name>D3Q1W5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017403.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2138"/>
    <dbReference type="EnsemblBacteria" id="ADD41832">
        <property type="protein sequence ID" value="ADD41832"/>
        <property type="gene ID" value="Snas_2138"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2138"/>
    <dbReference type="eggNOG" id="ENOG5032VCE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121293_0_0_11"/>
    <dbReference type="OrthoDB" id="1733975at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="182" mass="20744" checksum="BA86691CDF434C0B" modified="2010-04-20" version="1">MGIMADRLASMVVKATSPDGQIEGELRDRDAVSVAFRGDTYRHYTEYSLGTQLSRLALRMWTGYQRGYDEAVAEATGRPVSRSQETWDANRRRFRQEQAATTVTGMSTDGWIYIQNTGMTSWHVVIRQGTLSKLDEDQFVAELMDAYNTMITEYRFATADLRAKHYGVSFQPRNPPVKELRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1Z1</accession>
    <name>D3Q1Z1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41858">
        <property type="protein sequence ID" value="ADD41858"/>
        <property type="gene ID" value="Snas_2165"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2165"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_88_16_11"/>
    <dbReference type="OMA" id="LDRHEHG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="165"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="318" mass="34945" checksum="8D8AE0AC72CA062E" modified="2010-04-20" version="1">MVTTERITAWRPSVPGITEAFHARFTDHVYPMHTHEAWTLLIVDAGAVRYDLDHHEHGALRATVTLLPPHVPHNGEAASSGGFRKRVLYLDAAQLGPRLIGPAVDAPDIRDAAMRDQIDRLHRSLWLPGDELEAESRFSLIRDRLRRHLEHRPVPVEAADPGLAHRLRDLLDARVVAGLTLAEASRILHAHPAHLVRSFSRAFGLAPHQFLTGRRVDLARRLLLDGMPPAQAAVASGHHDQSHLTRHFKRVVGTTPGRFATSRKTNALTPARLPLVAGTLPAVSRATGVPPPPPRRPRPPVPRPSPRRGGSPGRGAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q204</accession>
    <name>D3Q204_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4190 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2179</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017442.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2179"/>
    <dbReference type="EnsemblBacteria" id="ADD41871">
        <property type="protein sequence ID" value="ADD41871"/>
        <property type="gene ID" value="Snas_2179"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2179"/>
    <dbReference type="HOGENOM" id="CLU_1642699_0_0_11"/>
    <dbReference type="OMA" id="SMVCGIA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025241">
        <property type="entry name" value="DUF4190"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13828">
        <property type="entry name" value="DUF4190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4190" evidence="3">
        <location>
            <begin position="80"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="161" mass="16854" checksum="DBB92A3FBC088040" modified="2010-04-20" version="1">MTYDPKNPHYDPYTAPPVYDNQPVTGGGYPDGGYPDSPQQQGGYDQYAYQQQPPGPAYNAAGYSPPPMQMYQAPENGSGTAALVLGILGLVGCGLCAIPAVICGHMGMKKADQGLADNRGQAQAGLIMGYIGVAFLVLALLYVVFMLVMFGALASSSTTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q284</accession>
    <name>D3Q284_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4166</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019388.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4166"/>
    <dbReference type="EnsemblBacteria" id="ADD43817">
        <property type="protein sequence ID" value="ADD43817"/>
        <property type="gene ID" value="Snas_4166"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4166"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_1_3_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1049" mass="115058" checksum="8418C9097AF45AC3" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2A4</accession>
    <name>D3Q2A4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4187</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019408.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4187"/>
    <dbReference type="EnsemblBacteria" id="ADD43837">
        <property type="protein sequence ID" value="ADD43837"/>
        <property type="gene ID" value="Snas_4187"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4187"/>
    <dbReference type="eggNOG" id="COG3467">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067890_0_1_11"/>
    <dbReference type="OMA" id="CHLGFVR"/>
    <dbReference type="OrthoDB" id="1374795at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024747">
        <property type="entry name" value="Pyridox_Oxase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12900">
        <property type="entry name" value="Pyridox_ox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="23312" checksum="010CED525FCB3DE3" modified="2010-04-20" version="1">MTFTPTPRTTSLRVPEKLRYDAEEAYAILDEAYICHIGYAADGVPRVLPTAYARIGDTLYFHGSTGSRAFLNGRDNGVDVCVTVTIHDGIIFSRSWFHHSANYRCVMAHGRAYLVTDEIEKWDALAAIVDHLAPGRSEQSRPPTQKELAQTGVLALRLNEVSVKTRSGGPGEDPDDIGLPYWGGEVPLRTVALEPIPDDDTTVPVPAHLTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2F4</accession>
    <name>D3Q2F4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019458.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4238"/>
    <dbReference type="EnsemblBacteria" id="ADD43887">
        <property type="protein sequence ID" value="ADD43887"/>
        <property type="gene ID" value="Snas_4238"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4238"/>
    <dbReference type="HOGENOM" id="CLU_1894914_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="134" mass="13917" checksum="85BDEE398E306116" modified="2010-04-20" version="1">MPNVKQIWRTKGMIDAPTGDETLSPAKALTAIMADVETLPDDVEVLKADQSAIRTEIASLAQSLADTLAPALLAALAEALKTGITDDVLVSAAEQGVRRVLGSLDPEPGLIAPTPSAPTPPSRDQGVKPTVTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2F6</accession>
    <name>D3Q2F6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4240"/>
    <dbReference type="EnsemblBacteria" id="ADD43889">
        <property type="protein sequence ID" value="ADD43889"/>
        <property type="gene ID" value="Snas_4240"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4240"/>
    <dbReference type="HOGENOM" id="CLU_1757707_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="148" mass="16829" checksum="8717F91B76F0C07D" modified="2010-04-20" version="1">MPIIEPSYEILMWGDAIGGMMPGVVDMGGEHVRGEHVQWDTWLCMWREDVGPGLAAGGLIALTEHYDGRVVVKICLSGRAWHRAYPTEIDARDAVARYLAASPRAWENSPKSQRHRPTSERWRPDWAEMPDGAPDGEVWRTARRQPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2J6</accession>
    <name>D3Q2J6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Beta-glucosidase</fullName>
            <ecNumber evidence="2 6">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4280</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="2 6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4280"/>
    <dbReference type="CAZy" id="GH1">
        <property type="family name" value="Glycoside Hydrolase Family 1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43929">
        <property type="protein sequence ID" value="ADD43929"/>
        <property type="gene ID" value="Snas_4280"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4280"/>
    <dbReference type="eggNOG" id="COG2723">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001859_1_3_11"/>
    <dbReference type="OMA" id="DWVYVVP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017736">
        <property type="entry name" value="Glyco_hydro_1_beta-glucosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="Glyco_hydro_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="PTHR10353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03356">
        <property type="entry name" value="BGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="406"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="399"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="445" mass="49055" checksum="6E97AD88A6AE96DE" modified="2010-04-20" version="1">MTAMPRFPDGFHWGVATSAFQIEGALDADGRGRSVWDTFTATPGKIRDGHTAATACDHYRRFGEDIDLMRRLGIDVYRFSIAWPRVFPDGHGKVNTAGLDFYDRLVDALLAANLTPMPTLFHWDLPQSLEDAGGWLNRDTAAHFADYASTVAQRLGDRVNDWITLNEPFEHMALGYALGQHAPGHMMLLESLPVAHHQLLGHGLATARLRAAGAKRVLLTNSYTPVEPATASEADAAAAAAYDALHRGLFTDPVVLGRYPDLSAFGADELPFVHDDDLDVIATPLDGLGVNYYAPTKLAAAVDGPLPFTMTEYPDADKTAFDWPVVPDGMRRILVELTERYGDALPPLWVTENGCSFPDGPGDDGAVHDDRRISYLDSHIRAVHDAIEQGADVRGYLTWTLCDNFEWAEGYHQRFGLVHVDHDTQKRTPKDSFAWFAGMLAEQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2M8</accession>
    <name>D3Q2M8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6156"/>
    <dbReference type="EnsemblBacteria" id="ADD45779">
        <property type="protein sequence ID" value="ADD45779"/>
        <property type="gene ID" value="Snas_6156"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6156"/>
    <dbReference type="eggNOG" id="ENOG5033XY6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097567_0_0_11"/>
    <dbReference type="OMA" id="LLHYSQW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="27"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="234" mass="25679" checksum="BCCD2888A863BEFA" modified="2010-04-20" version="1">MGEPNLPTVDRPDVGTILVSEWIVRTPERQEAAADALHAGWAELATTPGFLSLSTFASLDGERLLNYAQWTDDEAHREFMRVDRPELVAKIDAAVPGIERPGVKRFRLHRSVDFGLDSAPGCVVVIQFETDGDEWAERLVDEVVARQDKQPFGASYAHFHISKDGDRMLNYVGFRDAEAHETAVNSPAMTKPGGIFEAIGAMSGVTGLGFKRYDLRRGLANPEVTTPAGRTGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2P3</accession>
    <name>D3Q2P3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021365.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6171"/>
    <dbReference type="EnsemblBacteria" id="ADD45794">
        <property type="protein sequence ID" value="ADD45794"/>
        <property type="gene ID" value="Snas_6171"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6171"/>
    <dbReference type="eggNOG" id="COG3824">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123836_1_0_11"/>
    <dbReference type="OMA" id="GEWYAGV"/>
    <dbReference type="OrthoDB" id="1867074at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010428">
        <property type="entry name" value="Zincin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038555">
        <property type="entry name" value="Zincin_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06262">
        <property type="entry name" value="Zincin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="113" mass="12665" checksum="3F5F65DDF2CE5B3F" modified="2010-04-20" version="1">MSEERFEELVSDALDLVPPALMDNLDNVVVLVEAEPPGDDKHLLGLYEGYALPDRGWDYGGVLPDKITIFRGPLLRMCQTEEEVVDEVTITVVHEIAHHFGIDDARLHELGWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2V2</accession>
    <name>D3Q2V2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_6232</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021424.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6232"/>
    <dbReference type="EnsemblBacteria" id="ADD45853">
        <property type="protein sequence ID" value="ADD45853"/>
        <property type="gene ID" value="Snas_6232"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6232"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_3_11"/>
    <dbReference type="OMA" id="GWNFLVQ"/>
    <dbReference type="OrthoDB" id="1558246at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
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        </location>
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            <end position="128"/>
        </location>
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        <location>
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        <location>
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        <location>
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            <end position="386"/>
        </location>
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            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="489"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="17"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="535" mass="56805" checksum="600B8DA07C9BA3E7" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q322</accession>
    <name>D3Q322_STANL</name>
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        <submittedName>
            <fullName evidence="3">Hemolysin-type calcium-binding region</fullName>
        </submittedName>
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        <name evidence="3" type="ordered locus">Snas_0274</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
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        <lineage>
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    </organism>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0274"/>
    <dbReference type="EnsemblBacteria" id="ADD39992">
        <property type="protein sequence ID" value="ADD39992"/>
        <property type="gene ID" value="Snas_0274"/>
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    <dbReference type="KEGG" id="sna:Snas_0274"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114502_0_0_11"/>
    <dbReference type="OMA" id="DIQANSG"/>
    <dbReference type="OrthoDB" id="1715963at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
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        <property type="entry name" value="Hemolysn_Ca-bd"/>
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        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="ADD39992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q380</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
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        <lineage>
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            <taxon>Glycomycetales</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
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                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
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                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
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                <person name="Jeffries C.D."/>
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                <person name="Markowitz V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="OMA" id="TCVPCAY"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="120" mass="13112" checksum="9CA6D2E941CC9F6D" modified="2010-04-20" version="1">MYDDPTGQKFGIPTFYWRGAPAGFATRRQLRATGLCPGGQDVAGQIKWRGIGGERTAYLYRIDLAKPKRTATPRVLAALDKALRARKTCGTCGQVKPYFIRTKFDECAECVEAAGGCYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3P1</accession>
    <name>D3Q3P1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ADD43958">
        <property type="protein sequence ID" value="ADD43958"/>
        <property type="gene ID" value="Snas_4311"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4311"/>
    <dbReference type="HOGENOM" id="CLU_2132016_0_0_11"/>
    <dbReference type="OMA" id="VCEEDME"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="113" mass="12103" checksum="FEC2A218DD91A79B" modified="2010-04-20" version="1">MRVAKEVRANPTDLARLAEAFLTESKDLFGALKTARGEISLGGDVFGNADAAAKVQAAYTGAIEAAGTDVERLIAVCEEDMESLYQVAFAYQYTDQNNGQTIDNVDDNNPLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Q9</accession>
    <name>D3Q3Q9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4329</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019547.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4329"/>
    <dbReference type="EnsemblBacteria" id="ADD43976">
        <property type="protein sequence ID" value="ADD43976"/>
        <property type="gene ID" value="Snas_4329"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4329"/>
    <dbReference type="HOGENOM" id="CLU_1276973_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="216" mass="23606" checksum="EDDF072A0219F2D0" modified="2010-04-20" version="1">MNNLTVAHKRVLVVDESVDVTELEKLAADSGWTMAGRFSQGFDESVELQWSADSGVDVAYIEFHSDGVRMVTVRGQDESAVDAVAEIVRGAVTTRDLDSLLDDVSKDPGPEPTALVRGWRELALACTHSHPDQPMDERLPAALETALRHDNRQVRLRGLVVADALGGRWPKLVDLVLARQGEETELGYVVEVFAQLRDDQAEDAEAAEDDKGSADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3S5</accession>
    <name>D3Q3S5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019563.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4345"/>
    <dbReference type="EnsemblBacteria" id="ADD43992">
        <property type="protein sequence ID" value="ADD43992"/>
        <property type="gene ID" value="Snas_4345"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4345"/>
    <dbReference type="eggNOG" id="ENOG5034AHP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1433688_0_0_11"/>
    <dbReference type="OrthoDB" id="1860120at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="189" mass="20119" checksum="3BDF001D2AC036D6" modified="2010-04-20" version="1">MTDGANRALWIIVGLVLAAVGGLGVAAHSGRLRFADPDDPLLSGAVIDLWHRGDPWNLAVVIVLGLLLVIVGIVLFGREFRRRGTSRIDDLSHPGERGDTVVRAAALINCLERDVATGRGIVKVSATITGHTDSPRVWLWVGLAPGATVTQAREHVDESLRRFTTTSGITPGSVDVTVLPTAKAQARVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q413</accession>
    <name>D3Q413_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6278</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021469.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6278"/>
    <dbReference type="EnsemblBacteria" id="ADD45898">
        <property type="protein sequence ID" value="ADD45898"/>
        <property type="gene ID" value="Snas_6278"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6278"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="AINQVEK"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="338" mass="36498" checksum="89C614C65FCDDF97" modified="2010-04-20" version="1">MEKRSAPTLDTVAARAGVGRGTVSRVINGSSRVSQEARDAVNRAITELGYVPNHAARSLVTRRTDVIALVISETEDRMWGEPYFADVIRGITRQLSESGLRLMFTLASTAEDRSRLETYLLGKHVDGALLISLHGDDPLPRHLEGSGLPVVLCGAPVGETDVPFVDSDNRGGARQAVEHLASTGRRRIAAITGPQDMSVGIDRLTGYREALRTEGLPEDPALMEPGDFSEAAGVTAMRALLDRVPDLDAVFAASDPMAFGALRVLRERGIRVPEDVAVVGFDDSPRAEHSEPPLTTVRQAAEPMGREMARLIQARIRGENPDPPSTILSTRLIVRESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q416</accession>
    <name>D3Q416_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_6281</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021472.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6281"/>
    <dbReference type="EnsemblBacteria" id="ADD45901">
        <property type="protein sequence ID" value="ADD45901"/>
        <property type="gene ID" value="Snas_6281"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6281"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="OMA" id="QYIYQMA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="277"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="82"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="309" mass="34532" checksum="798144D3A40358E5" modified="2010-04-20" version="1">MTSTEQRAGRSGARLASRLDHRGSPYLFVSPYFLLFAAFGLFPLGFTLWVSLHRWKLAGDKEFVGIDNYTFLLTNERFGAAVVNTLGMFTLATVPQLLLALLLANALNKRMRGLLYLRMGVLIPMVTSVVAVAIVFSQLFSHRYGMINWAVELFGGEKIDWTASKLTSWTAIATMVDWRWTGYNAIIFLAAMQAIPRDLYEAAAIDGASPRRQFWQITVPQLKPVIIFTVFISTMGGLMLFAEPMMFGNGRLDGGTRGDFQTIGLYIVQAFRERNNFGLAAAAAWLLFVLILVTALVNYLFVNRLRGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q471</accession>
    <name>D3Q471_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_6339</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021527.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6339"/>
    <dbReference type="EnsemblBacteria" id="ADD45956">
        <property type="protein sequence ID" value="ADD45956"/>
        <property type="gene ID" value="Snas_6339"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6339"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_5_2_11"/>
    <dbReference type="OMA" id="DCPWIVE"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003012">
        <property type="entry name" value="Tet_transcr_reg_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00400">
        <property type="entry name" value="TETREPRESSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="6">
        <location>
            <begin position="16"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="225" mass="25054" checksum="DA48AFD56598B5CE" modified="2010-04-20" version="1">MPTASDKPVRSGRPPRLSRAEIIAAAKRIVERDGVEKLTMRLLAREVGSAPMALYHHVRDKRELLLALLDDLAERVPRPELPDDPVERIIAATVAIHDGLLEFPWMVRILAEGDLLSPKALWFPEAVIDAGIRAGLSEGEAVHAYRSVWYFTVGELIVRTAARERVGVPTYQAEVFQELDPRRTPRLAAISDRWLSWQLADTFRPGLRAIVDGLLRAVRGGGCSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4B0</accession>
    <name>D3Q4B0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock protein 70</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0352</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0352"/>
    <dbReference type="EnsemblBacteria" id="ADD40070">
        <property type="protein sequence ID" value="ADD40070"/>
        <property type="gene ID" value="Snas_0352"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0352"/>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_303999_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="381"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="858" mass="91032" checksum="2F462F214B1DA2AB" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4W2</accession>
    <name>D3Q4W2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">acVLRF1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017713.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2459"/>
    <dbReference type="EnsemblBacteria" id="ADD42142">
        <property type="protein sequence ID" value="ADD42142"/>
        <property type="gene ID" value="Snas_2459"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2459"/>
    <dbReference type="eggNOG" id="COG1503">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082731_0_0_11"/>
    <dbReference type="OMA" id="RWVEGFT"/>
    <dbReference type="OrthoDB" id="1868138at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042226">
        <property type="entry name" value="eFR1_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040783">
        <property type="entry name" value="VLRF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18859">
        <property type="entry name" value="acVLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="acVLRF1" evidence="1">
        <location>
            <begin position="89"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="227" mass="24224" checksum="BEE3195F5F9A34DF" modified="2010-04-20" version="1">MSTNRPAAGGGREIIVTVQRFGKWIDGFDTRHTVTGATLGLSGLRVTAEDGSLAVCELPLWGGGPSTPPEGDTRDLIDAFAEQALKPYRVGVLLARRRGFAVGVFTGDRLTESKVDSSYVQSRTAAGGWSQQRYARRRGNQAAHAAGKAADTVHRLLATNIDDLAAVVTAGDRAAVDAILADPRLAVLTDKLAPPHIGDIGEPKLATLKELPKKFWTVRIHLTEPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q502</accession>
    <name>D3Q502_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NfeD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017753.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2500"/>
    <dbReference type="EnsemblBacteria" id="ADD42182">
        <property type="protein sequence ID" value="ADD42182"/>
        <property type="gene ID" value="Snas_2500"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2500"/>
    <dbReference type="eggNOG" id="COG1585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116732_2_0_11"/>
    <dbReference type="OMA" id="AMPEFGM"/>
    <dbReference type="OrthoDB" id="1951939at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002810">
        <property type="entry name" value="NfeD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01957">
        <property type="entry name" value="NfeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="NfeD" evidence="3">
        <location>
            <begin position="51"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="144" mass="15385" checksum="E13353F9C9081701" modified="2010-04-20" version="1">MAWIIWLAVAVALGIAELFTLTFVLLMIGAGAAAASLAAALGSPVELQGLVFVVVSVLSLIGIRPWAKKLRDNRSGPDAKIGLQALEGAEALVLERVDSQHGLIKVQGQEWTARSYDGKQVLEQGEEVNIVEIRGATAMVWRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q513</accession>
    <name>D3Q513_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44062">
        <property type="protein sequence ID" value="ADD44062"/>
        <property type="gene ID" value="Snas_4416"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4416"/>
    <dbReference type="HOGENOM" id="CLU_3140948_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="49" mass="5665" checksum="5C09A4DF6E99328C" modified="2010-04-20" version="1">MTETSGLFWTRASLTASKLFGSPWSFNHSPATTQERQRKPQSYVYSLWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q514</accession>
    <name>D3Q514_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44063">
        <property type="protein sequence ID" value="ADD44063"/>
        <property type="gene ID" value="Snas_4417"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4417"/>
    <dbReference type="HOGENOM" id="CLU_3084956_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="52" mass="5401" checksum="6E05DD5D71272235" modified="2010-04-20" version="1">MAAICLLLTIAAILGLIAAIIAKSSHRPDAGETVRDFGIGAFIAACLLWFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5U9</accession>
    <name>D3Q5U9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0534</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015819.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0534"/>
    <dbReference type="EnsemblBacteria" id="ADD40248">
        <property type="protein sequence ID" value="ADD40248"/>
        <property type="gene ID" value="Snas_0534"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0534"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_11"/>
    <dbReference type="OMA" id="GMWRTQA"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="26"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="333"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="568" mass="59199" checksum="5CF4DF655FCB46B9" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q638</accession>
    <name>D3Q638_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017784.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2532"/>
    <dbReference type="EnsemblBacteria" id="ADD42213">
        <property type="protein sequence ID" value="ADD42213"/>
        <property type="gene ID" value="Snas_2532"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2532"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_4_2_11"/>
    <dbReference type="OMA" id="TRVCEAT"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="18"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="166" mass="18535" checksum="FB53C581C6F764C2" modified="2010-04-20" version="1">MSSSVEPFPTCPNTSSVRTDIAWLLHRAAQRIRQEWDVAAREHGLRDMRDWIVLAAVGEGEKRTQLAIGQELGLDKTTLMSVLDRLERDGFVVRTVDPNDRRARVPELTEIGAKVRDLKVPARQRVEEAALTGASTEDRHVFFSVLSQLAGVDSDSEEPSHGSCMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q691</accession>
    <name>D3Q691_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_2586</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017837.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2586"/>
    <dbReference type="EnsemblBacteria" id="ADD42266">
        <property type="protein sequence ID" value="ADD42266"/>
        <property type="gene ID" value="Snas_2586"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2586"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OrthoDB" id="1851240at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="15"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="454" mass="46515" checksum="CC6BDC96FE66AC14" modified="2010-04-20" version="1">MAVASPTAPQTRSRAVLPIACAAIVPVLMNYTSPLISLPETAAGVGAGPLAQTWIMNASPLGLAAALLVAGILADNFGRRRMLLVGALGMGLTSAIVALSTDAAVLIGARIGQGVAGAAIIAASLGLLGSNYTDPAERGRATGLWAMALGAGLAVGPLATGALTEAWSWRAIYWVYAAVSIALAVAVTRLDESRAEQRRPVHYAGIVSFVSGMCFLLAAITLARTGWTRLPVLVLLGATVVALAGFVALSLRHHAPMVDMRLFRHRPFLLSVTGSGLNGLLMIGVMSVLPTAWQHTHHFDALHMAIPFTVYPLAALVIARLARYVPVPPIRLLAIGYGLSLAQLLMVGSMTNWSMPRVVISYLIAGIGAGFVNAANARMAVDSVPSANASMGSGAANTARYVGSAMGVAIGIAVVGGLGWADGVNSVLIGSAVLLGLAALGYASVGRVRRPSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6H5</accession>
    <name>D3Q6H5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold-3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4574"/>
    <dbReference type="EnsemblBacteria" id="ADD44218">
        <property type="protein sequence ID" value="ADD44218"/>
        <property type="gene ID" value="Snas_4574"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4574"/>
    <dbReference type="eggNOG" id="COG0657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_485628_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_3" evidence="2">
        <location>
            <begin position="331"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="561" mass="58928" checksum="3B9CA76CA63EF02B" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q724</accession>
    <name>D3Q724_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Porphobilinogen deaminase</fullName>
            <shortName evidence="6">PBG</shortName>
            <ecNumber evidence="6">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Hydroxymethylbilane synthase</fullName>
            <shortName evidence="6">HMBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pre-uroporphyrinogen synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hemC</name>
        <name evidence="9" type="ordered locus">Snas_0710</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
        <text evidence="6">Binds 1 dipyrromethane group covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">The porphobilinogen subunits are added to the dipyrromethane group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the HMBS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0710"/>
    <dbReference type="EnsemblBacteria" id="ADD40423">
        <property type="protein sequence ID" value="ADD40423"/>
        <property type="gene ID" value="Snas_0710"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0710"/>
    <dbReference type="eggNOG" id="COG0181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019704_0_2_11"/>
    <dbReference type="OMA" id="NAHEWAG"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018160">
        <property type="term" value="P:peptidyl-pyrromethane cofactor linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00260">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PTHR11557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001438">
        <property type="entry name" value="4pyrrol_synth_OHMeBilane_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="SSF54782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobil_deam" evidence="7">
        <location>
            <begin position="5"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobil_deamC" evidence="8">
        <location>
            <begin position="228"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="modified residue" description="S-(dipyrrolylmethanemethyl)cysteine" evidence="6">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="307" mass="32450" checksum="8EC5D955C12B6F1E" modified="2010-04-20" version="1">MSVKVRIGTRSSPMALAQADRVSAALTALDPDVAVEIVPFTTSGDKWMGPLSQLGGKGAFTKEVDAALVEGTCDLCVHCVKDIPGDRDLPEGTVIAAHLERDDVRDALVHPGGLSLSDLPDGSRIGTSSPRRAAQLALHWPRLSPLPIRGNANTRLAKLDAGDFDALLLAVSGLERLALTDRITEILDVDTMVPAIGSGTLALQCRTDDTPVRDLVARLDDPMTSWRTEAERSMLRALNGHCHSPIAGYAIQESEGVLSLHGRVMSLDGSTVLEARESGADATALGTSVAEALLRQGARELIDSLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q733</accession>
    <name>D3Q733_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016003.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0720"/>
    <dbReference type="EnsemblBacteria" id="ADD40432">
        <property type="protein sequence ID" value="ADD40432"/>
        <property type="gene ID" value="Snas_0720"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0720"/>
    <dbReference type="HOGENOM" id="CLU_1905473_0_0_11"/>
    <dbReference type="OrthoDB" id="1627730at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="133" mass="14757" checksum="9FFB741972319DE4" modified="2010-04-20" version="1">MSITALPFDRCGVAIAKLEVDIRTRPAERRWRDAVREGLTALREALSPNNYNAAGAEELFRDAPRLARAIRRIGAEREQLASRADALVAIGSQLSPATLAASVRQLLDEVRQHRRRVSDLLHEAYVVDIGGEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7G2</accession>
    <name>D3Q7G2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018004.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2757"/>
    <dbReference type="EnsemblBacteria" id="ADD42433">
        <property type="protein sequence ID" value="ADD42433"/>
        <property type="gene ID" value="Snas_2757"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2757"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074359_0_0_11"/>
    <dbReference type="OMA" id="AWNMTAD"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="180"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="322" mass="36062" checksum="34365FE6EBF5FCD5" modified="2010-04-20" version="1">MKTTGFQVGRTDALVDAWTRSAPGDPITTDRFRRLVLLDANFDPEGLRLAWDGDRVIGAAYAVRRRVAMVGDDLEPGRGWIPFYFVDPDRRRHGVGKRLLTEAMDWLRSCGRTEVDFSSYTPNYILPGLDADRYPAAKSLMDSLGFRTLYQASAMTLPIGEHLVPDKVRARVTELRTQGYSFSSPSPDELVPLIELANDHFNADWGRVIRETAAAGLPPDRILVARDPGGEIIGWGMCTAYEGIVDRFGPFGVVDRLRGLGLGEALLHLCLERMRALGGQNAWFLWTGEQTPAGHLYRKTGFTVTRRFHIMRAQLTDHKEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7I0</accession>
    <name>D3Q7I0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019893.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4679"/>
    <dbReference type="EnsemblBacteria" id="ADD44322">
        <property type="protein sequence ID" value="ADD44322"/>
        <property type="gene ID" value="Snas_4679"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4679"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_672520_0_0_11"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="409" mass="42184" checksum="B0D9CD806BA4BBE8" modified="2010-04-20" version="1">MSRPSSRLRDLPATYWRLCVSHGISSFGDFLRMTTIAFWAYEASDGSAAAVGAFATTELLVAMVSGSVAGVIADRWNRVTVMIASDFGRVATGVVLVAAVVWNHIPAAVVAVAASGFLTALFTTCRGALLPGVVPRELLARGNSLMITVEQVAVVASPGIAAVLFGTLGAAPALVIDALSFLVSGVLILGLRYREPAPSGEDEDGEAESSRNGAAVNWLVPVGFAVAALAAMMYQFGANSSTLVAFLPEDLDRPVTDAFWFAMVSGAIQLFAGTLLSALAHRLRLRATMVLSAACVMVGGWTLAYAPNLFTAVAGVGIIACANIPFRVAFETLPQLLVPSRVLGRVIGVVKSVSASAFIAGTLGGGLIADQAAPRTSLVVSALILSLGALLSLGLLTRTVTRAPKTPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7J2</accession>
    <name>D3Q7J2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4691</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019905.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4691"/>
    <dbReference type="EnsemblBacteria" id="ADD44334">
        <property type="protein sequence ID" value="ADD44334"/>
        <property type="gene ID" value="Snas_4691"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4691"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="MMTVSNV"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="340" mass="36545" checksum="A9DBFF004FF5E084" modified="2010-04-20" version="1">MRVTLRDVAEQAGVSMMTVSNVVNGNHARVSQETIGRVRRIAAELGYIPNASARSLAARSSRMIGLLIPAADSDSLTISPHNMAILGQIERALRKRDYHLLLRGIADPEEVTAALKSWDLDGAILLGFHEAELARISGPAVDAARVLAIDGYTQGPLISGVRSDDFAGARLAADHLLELGHRAIVFTGPPPAPSGVVRQRLDGFRQAFADHGSTWDETLLEPVDTNTHEHGRRLGLRLRADHPEVTAVFATADILAIGIMEGLAESGAAVPTDVSVVGFDDLDLCRYVTPKLTTIAQDITAKADTAVELLLRSIESEEHADQPVTLDVHLVRRDSTAPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q813</accession>
    <name>D3Q813_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">N5-carboxyaminoimidazole ribonucleotide mutase</fullName>
            <shortName evidence="3 4">N5-CAIR mutase</shortName>
            <ecNumber evidence="3 4">5.4.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5-(carboxyamino)imidazole ribonucleotide mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purE</name>
        <name evidence="7" type="ordered locus">Snas_0806</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="EC" id="5.4.99.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.18" evidence="3 4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0806"/>
    <dbReference type="EnsemblBacteria" id="ADD40518">
        <property type="protein sequence ID" value="ADD40518"/>
        <property type="gene ID" value="Snas_0806"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0806"/>
    <dbReference type="eggNOG" id="COG0041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094982_2_0_11"/>
    <dbReference type="OMA" id="SNSIDGW"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034023">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024694">
        <property type="entry name" value="PurE_prokaryotes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001338">
        <property type="entry name" value="AIR_carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 3 4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="6">
        <location>
            <begin position="6"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001338-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="185" mass="18962" checksum="8DA96B7EEAA0C90A" modified="2010-04-20" version="1">MTDNQPLVGVIMGSDSDWPTMKAAVEMLDHFGVAHEVRVVSAHRTPHAMLTYADEAAARGLRVIIAGAGGAAHLPGMVASATPLPVIGVPVPLKHLDGMDSLLSIVQMPGGIPVATVSVAGAKNAGLLAVRVLGVADPALRLAMSDYQRELVDMVADKNTRLQETVANDSAAKPGGGFGFVPGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8I0</accession>
    <name>D3Q8I0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018125.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2879"/>
    <dbReference type="EnsemblBacteria" id="ADD42554">
        <property type="protein sequence ID" value="ADD42554"/>
        <property type="gene ID" value="Snas_2879"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2879"/>
    <dbReference type="eggNOG" id="COG5517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106738_1_1_11"/>
    <dbReference type="OMA" id="HQVTNAR"/>
    <dbReference type="OrthoDB" id="1736098at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="20"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="166" mass="18290" checksum="8DEEFD36FC6D1503" modified="2010-04-20" version="1">MYVNSSEALTATEPAAVVAELRDRTEIADALHRFALGQDLKDRELFASAFATEAELDFRPAAAKWGSRPPVMSGRDTIVTTILGMFTGRVDTTHQVTNARIAIDGDTARLTALVEAQHLLRADRSVRALLKNPYDVALTRDGDRWLITTMRIDNAWYTGDPVAIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Z5</accession>
    <name>D3Q8Z5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_0893</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016175.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0893"/>
    <dbReference type="EnsemblBacteria" id="ADD40604">
        <property type="protein sequence ID" value="ADD40604"/>
        <property type="gene ID" value="Snas_0893"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0893"/>
    <dbReference type="eggNOG" id="COG1087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_10_11"/>
    <dbReference type="OMA" id="GEHLICN"/>
    <dbReference type="OrthoDB" id="1597849at2"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="8">
        <location>
            <begin position="4"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="321" mass="34165" checksum="670BA399FDDCFEDC" modified="2010-04-20" version="1">MKYLVTGGAGYVGSVVATMLLEAGHEVVVLDDLSTNGDTGIPAGATVVRGRIHEAAEVLDDSFDGVLHFAGYIANGESMAKPDIYWDVNVVGTLSLLNAMHAAGVRSLVFSSSASVYGNPSELPATENAITRPTSTYGANKLAADYAITNYCTAFDIAAVSLRYFNVAGAWKDASGVWHGERHDPETHLIPLILAAANGDRGALKLYGEDYDTPDGTCVRDYIHVADLARAHLLALANQQPGEHQIYNLGNGNGFSNREVIAAVERVTGLTVPFKPAPRRPGDPDTLVASSAKAAAELGWRPEKPSLDDIIADAWEFYRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9F9</accession>
    <name>D3Q9F9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2966</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018212.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2966"/>
    <dbReference type="EnsemblBacteria" id="ADD42641">
        <property type="protein sequence ID" value="ADD42641"/>
        <property type="gene ID" value="Snas_2966"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2966"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_482046_0_0_11"/>
    <dbReference type="OMA" id="HILRVVH"/>
    <dbReference type="OrthoDB" id="1518440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017174">
        <property type="term" value="F:glycine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014369">
        <property type="entry name" value="Gly/Sar_N_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51600">
        <property type="entry name" value="SAM_GNMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="5">
        <location>
            <begin position="88"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransf_11" evidence="4">
        <location>
            <begin position="366"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="572" mass="65432" checksum="4C5BB2D6C257540E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9P6</accession>
    <name>D3Q9P6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4952"/>
    <dbReference type="EnsemblBacteria" id="ADD44592">
        <property type="protein sequence ID" value="ADD44592"/>
        <property type="gene ID" value="Snas_4952"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4952"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_3_11"/>
    <dbReference type="OMA" id="CEGGFHS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="21"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="417" mass="42545" checksum="E8BD8A385F8BCA86" modified="2010-04-20" version="1">MKREKMTGNPASPQMARAINDRLALDLLVEHGRLSAPQLRELTGLSRPSIADLIERLQEGGLVKQVGESGKKRRGPNAKVYGLVADYVHVAGVDLRGGTIHVALADLGGAIVAESRRTINPDHTLASLIRRAVADAVRKLDREVSALHTVVVAAPGFINQNTAELLPGYEFPGWDAELLPGLIDALDVPIAFENEADLAGTAELHHGAGAGRRDLAVLWLDRSVGASVILDGALRHGASGGSGEVGKLALPGAHLPAPGRASGGFHSLVSSEAVLALAADHGVETGPVAEVVARACEADDMASTSFVDALAARIALGALGLVAVVDPGLIVMSGDIGRAGASVLADRVAAHLSTLDATVTDIVPSTLPDNPVVTGAVLSALHIARDDVFGSSSRLAAAYGEEAEAAAAAESGAEAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9P8</accession>
    <name>D3Q9P8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020165.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4954"/>
    <dbReference type="EnsemblBacteria" id="ADD44594">
        <property type="protein sequence ID" value="ADD44594"/>
        <property type="gene ID" value="Snas_4954"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4954"/>
    <dbReference type="HOGENOM" id="CLU_1299117_0_0_11"/>
    <dbReference type="OrthoDB" id="1877572at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="24290" checksum="60ECA7D055BFA92D" modified="2010-04-20" version="1">MNDTVETVFFCFGLPVLLIGLAYLMIFEPIRRRRKKAVSAGSAWAKRHGWRYQKADNALVGRWQGEPFRNRGGAADVLYGVHRGRNIMMFTYGYHEAGVVTQSESFYTIVAVGLGSQRPWLQLKPRDEPRSHQLFDVFDIQSQDNQYSNHVFQSGLADWLLNDPRSRQQPVRFENADLLSWWGGPIDCDEAFATAEFLCDLADRVPDAARHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9S9</accession>
    <name>D3Q9S9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="7">6.3.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">D-Ala-D-Ala ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">D-alanylalanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ddl</name>
        <name evidence="12" type="ordered locus">Snas_4988</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020196.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4988"/>
    <dbReference type="EnsemblBacteria" id="ADD44625">
        <property type="protein sequence ID" value="ADD44625"/>
        <property type="gene ID" value="Snas_4988"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4988"/>
    <dbReference type="eggNOG" id="COG1181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039268_0_1_11"/>
    <dbReference type="OMA" id="NTTPGMT"/>
    <dbReference type="OrthoDB" id="764798at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000291">
        <property type="entry name" value="D-Ala_lig_Van_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011127">
        <property type="entry name" value="Dala_Dala_lig_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01820">
        <property type="entry name" value="Dala_Dala_lig_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01205">
        <property type="entry name" value="D_ala_D_alaTIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00843">
        <property type="entry name" value="DALA_DALA_LIGASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00844">
        <property type="entry name" value="DALA_DALA_LIGASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 7 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048795" description="D-alanine--D-alanine ligase" evidence="10">
        <location>
            <begin position="25"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="11">
        <location>
            <begin position="149"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR039102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ADD44625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="364" mass="38257" checksum="EBC995B5C7248003" modified="2010-04-20" version="1">MKKTKVAVVLGGRSVEHPVSCASAAGVIAALDPEQYEVVAVGITQAGQWLSVDARSAKLALGDGNVPEISADSGQHVVLAADPTMKDVAITDAAGGARVLSDVDVVFPVLHGAYGEDGTIQGLLEMADVPYVGSNVLSSAASMDKDFMKRLLKAEGIPVGDYVVLKRDQTLSEAEKQRLGLPVFVKPSRAGSSLGISKVTDWDDLDKAIATARAVDPKVLVEAAFTGVRELECGVLEREDGGAPDTTPPFEVLIAGTEGWFDFEAKYLASGSPYDLAPDLPEGTAERIRELAARVFTVMDCSDLARVDFFLASDGTVYVNEINTMPGLTPGSGVPVAWANAGVDYPELVARLVRLAANRGTGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA02</accession>
    <name>D3QA02_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_1004</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1004"/>
    <dbReference type="EnsemblBacteria" id="ADD40714">
        <property type="protein sequence ID" value="ADD40714"/>
        <property type="gene ID" value="Snas_1004"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1004"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_13_3_11"/>
    <dbReference type="OMA" id="NRMIRTA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048988" evidence="7">
        <location>
            <begin position="28"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="8">
        <location>
            <begin position="51"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="322"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="396" mass="40808" checksum="D0FDD76380C89AB0" modified="2010-04-20" version="1">MRHQVRFGLGAAAALLVVAGLPVPAHADEVRDDQWMLNALGIEQAHKETRGAGVTIGIVDSGVDATHPDLKGNVEAGQASWEGGKDGLKDTMGHGTAMASILVGHGHGDGGEDGVLGIAPEAKVKSVSIYPSSDPRDDPRGSHDRMVEGIRWLADEGVDVISVSQGGAGSDALEEAVKYAVEEKGIPLVASAGNTAGGPTGDVVVQAPAVYDNVFSATGTTKQGKFWDGSVEGTSPDDVTVAAPAEDVVHAWNDRGYDDNSGTSDSAAIVAGTIALMKAQWPDMSRETIEWRLTETADEKGKDGPDTKYGFGIVNPAEALTAHVDPPDGVSDEEINPEPNPKASASPSPSKDDGALTASDSGAGPVVWIVVAVVAILAAAVVSFILIRRRRQPPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAE4</accession>
    <name>D3QAE4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phenylalanine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="13">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="13">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">pheS</name>
        <name evidence="15" type="ordered locus">Snas_3056</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="13"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3056"/>
    <dbReference type="EnsemblBacteria" id="ADD42727">
        <property type="protein sequence ID" value="ADD42727"/>
        <property type="gene ID" value="Snas_3056"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3056"/>
    <dbReference type="eggNOG" id="COG0016">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025086_0_1_11"/>
    <dbReference type="OMA" id="DWHNFTA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00281">
        <property type="entry name" value="Phe_tRNA_synth_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004188">
        <property type="entry name" value="Phe-tRNA_ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022911">
        <property type="entry name" value="Phe_tRNA_ligase_alpha1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PTHR11538:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02912">
        <property type="entry name" value="Phe_tRNA-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="14">
        <location>
            <begin position="137"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD42727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="361" mass="39594" checksum="ABBE25C3F1DFE67D" modified="2010-04-20" version="1">MAMTYRSDPYDPKEAAYLSPQALDDAIATAEKAFAEAGDADTLASIKHLHLGDKAPISLARREIGSLPPAAKADAGKRVNTARQAVTVAYEARAEVLAAEAAQRVLREETVDVTVPVDRRPRGARHPLTLTAERIADFFTAMGYQISEGPEIEPEWFSFDALNIGPDHPARSMMDTFYLDAAGRGAASGLTLRPHTSSVQIHTMLTQEPPIYAVSPGRVYRTDEVDATHSPVFHQTEGIVIDKGITMAHLKGTLDHWAKAMFGVQARTRLRPSYFPFTEPSAEVDVWFAAHRDGPRWIEWGGCGMVNPRVLRACGIDPTIYSGFAFGMGIDRAVMLRHGVTDMRDMFDGDVRFPLALGTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAY4</accession>
    <name>D3QAY4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020351.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5145"/>
    <dbReference type="EnsemblBacteria" id="ADD44780">
        <property type="protein sequence ID" value="ADD44780"/>
        <property type="gene ID" value="Snas_5145"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5145"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115403_3_4_11"/>
    <dbReference type="OMA" id="HRQLWVT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="12"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="115" mass="12255" checksum="1E5C36F8BC03EF8F" modified="2010-04-20" version="1">MTLSIKTGPTADGGMVLTLDGEVDYATAPQIREKISQVLRADDVAYIKVDVAKVTVLDSTGIGTLVVAYRIARDVDVPVFVTNPTKFIKRLFAVVGAQELLEEPTDAFAATTGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAZ6</accession>
    <name>D3QAZ6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5157</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5157"/>
    <dbReference type="EnsemblBacteria" id="ADD44792">
        <property type="protein sequence ID" value="ADD44792"/>
        <property type="gene ID" value="Snas_5157"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5157"/>
    <dbReference type="HOGENOM" id="CLU_1179707_0_0_11"/>
    <dbReference type="OrthoDB" id="1708804at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="217" mass="23534" checksum="2BBC2D74EEAD14DC" modified="2010-04-20" version="1">MCTMSEPRFEAASDIDLDRDSAPAKRNRKRTLIIAVIAVVVVSLAGLGLYLTHDSPASEQPEDKPVLAEDPPPTGKYALRAVHSKLCLGVGPEIKDGEVNKRKEVFVQQKCEDRFPPTGLRAQGNGLYRLSVDHPDQGPGCGKVDGVTAGSLVQPTKCAKVDEQFFLFERTKDTYVIRLSADPELCLGIIDGSRKAGAQVLTEACGSPGQKWYVEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBE4</accession>
    <name>D3QBE4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">OMP decarboxylase</fullName>
            <shortName evidence="7">OMPDCase</shortName>
            <shortName evidence="7">OMPdecase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pyrF</name>
        <name evidence="9" type="ordered locus">Snas_3155</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H(+) + orotidine 5'-phosphate = CO2 + UMP</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the OMP decarboxylase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3155"/>
    <dbReference type="EnsemblBacteria" id="ADD42826">
        <property type="protein sequence ID" value="ADD42826"/>
        <property type="gene ID" value="Snas_3155"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3155"/>
    <dbReference type="eggNOG" id="COG0284">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060704_0_0_11"/>
    <dbReference type="OMA" id="QSAFFER"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01215">
        <property type="entry name" value="OMPdecase_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011995">
        <property type="entry name" value="OMPdecase_type-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43375">
        <property type="entry name" value="PTHR43375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02127">
        <property type="entry name" value="pyrF_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMPdecase" evidence="8">
        <location>
            <begin position="19"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="303" mass="31529" checksum="1B17CACE3E2D7F32" modified="2010-04-20" version="1">MGDLTFGARTAKALTKRGPLCVGIDPHSQLLRTWGLDDDVKGAERFCMTIVDALAGEVAFIKPQSAFFERFGSAGIGLLERVISESRHAGAQILLDVKRGDIGSTMQAYAQAYLDPASPLAVDAVTASPYLGVGSLQPMFDLASAHRRGVFVLALTSNAEGGQVQKAVRKDGRTVAQSVIDEVAAANADAEPMGSLGVVVGATISACRGDDAARSRQMTHGITHTARSGESAHDLDALNGPILVPGMGTQGGKPADLRRVLGRAATWAIPSYSRDIARHGPSAGGLRQAAKQAMEACAEAVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBT0</accession>
    <name>D3QBT0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5184</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020390.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44819">
        <property type="protein sequence ID" value="ADD44819"/>
        <property type="gene ID" value="Snas_5184"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5184"/>
    <dbReference type="HOGENOM" id="CLU_1061339_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="262" mass="27785" checksum="720B8F474BDACDC8" modified="2010-04-20" version="1">MKDSDEYVGFTPTLTNSTGETVEDVEVEFTISAPDGAAPPVAIQQGDPDEGGEHDTVAVKGEAIRGDATVDSSEGQFTIEHDPALDRVKFDGVPDSVPTDKIRPNGVDWSFTITNDTDTDITDGFIVIGLYADDGQRGLELGTEQKGCEETHDEDEVTRCEGVSLAAGESLTYDMKLFTDGTSEDLSKKVSLTVRMSYPTDAEQVRFASGETYTKADAASSDEILPVTGFSLGGYLAVGAGVIGLGAVMLLLASRRAARQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBY4</accession>
    <name>D3QBY4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5239"/>
    <dbReference type="EnsemblBacteria" id="ADD44873">
        <property type="protein sequence ID" value="ADD44873"/>
        <property type="gene ID" value="Snas_5239"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5239"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_3_5_11"/>
    <dbReference type="OMA" id="LSHEIRY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="97" mass="10437" checksum="102D490744ADEC8A" modified="2010-04-20" version="1">MDDEVTMLQAFKALAHPVRLGMLRRLAAAGEICACDFTDDFDISQPTVSAHLRTLREAGLVTTRRDGTTICYSLVPEALSELGDQLARIGDTAATVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC05</accession>
    <name>D3QC05_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DedA family membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5260</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DedA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020465.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5260"/>
    <dbReference type="EnsemblBacteria" id="ADD44894">
        <property type="protein sequence ID" value="ADD44894"/>
        <property type="gene ID" value="Snas_5260"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5260"/>
    <dbReference type="eggNOG" id="COG0586">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044208_2_2_11"/>
    <dbReference type="OMA" id="CCVIDGF"/>
    <dbReference type="OrthoDB" id="1928533at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032818">
        <property type="entry name" value="DedA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30353">
        <property type="entry name" value="PTHR30353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="241" mass="25798" checksum="8A37DD1AF98C3B15" modified="2010-04-20" version="1">MRICAECHTLLRVKELEHAIMDYIDPFMQTPWIFVLVFAIAFIDGFFPVVPGETTVIAAGAVAASTGYPNIALIIAVAALGAFGGDHVSYAIGRFAFGPIARRLKPGTKKKKAFDWAHDALEKRGGIVLIVARYIPGGRTAITITSGAVRYSLRKFSFFDSIAAVSWGVYSGMIGFLAGKTFEGRPLLALGLGFAIAIVCAGIMELVRFLLEKRAKAREALAVAVPAPRVEDAAAPVPVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC34</accession>
    <name>D3QC34_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GntR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0046</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015339.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0046"/>
    <dbReference type="EnsemblBacteria" id="ADD39768">
        <property type="protein sequence ID" value="ADD39768"/>
        <property type="gene ID" value="Snas_0046"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0046"/>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_4_11"/>
    <dbReference type="OMA" id="DDPVPSH"/>
    <dbReference type="OrthoDB" id="1045165at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD39768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="235" mass="25967" checksum="29625F6A3B2F6D71" modified="2010-04-20" version="1">MTNYTRRGLHGQTVREVARRILTGELPPGATIAVTELEAEMDVSRTAMREALKVLSAKGLVGARQKRGTFVRERSDWNLLDADIIRWQFADRSDEAFLDNLHELRGIVEPAGVRLAAERRTEADLRAIDAALAKMATAQAEGDTTLAVTADLEFHRALLTATHNELLERMEVLIETGLATRDRLVHGAHPHDDPVPSHRAVAEAVRRGFPAAAEQAMRELLDKAKNDQRRTTGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC37</accession>
    <name>D3QC37_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0049</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015342.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0049"/>
    <dbReference type="EnsemblBacteria" id="ADD39771">
        <property type="protein sequence ID" value="ADD39771"/>
        <property type="gene ID" value="Snas_0049"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0049"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="OMA" id="WAIAWRI"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="75"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="297" mass="32646" checksum="C0C10785748DE560" modified="2010-04-20" version="1">MSIKNRQARSGWGFLAPFLVLFVAFFILPILYAIYQSLFTVKRTGELGLGGQELSFSWFDNYTTALSDTAFVDSLWTVLIFALIQVPVMVLLALTLALLLESASARGVGFFRTAYFLPHGVPGVIASILWGFLYVPGISPLYNLFESVGLSVDFISPDTILLSIVNIVTWEFAGYNVLVLIAQLKAVNPNLFEAARVDGASPWRIIWHIKLPLARPAIVMATVFTIVGSLQLFAEPLVLRPVAASITYTYTPNLAAYNEAFFENNYQLAAAQAVVLAAVAMVLSFGFLRIFGRGDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTW9</accession>
    <name>D3PTW9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">DNA replication and repair protein RecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recF</name>
        <name evidence="10" type="ordered locus">Snas_0004</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the RecF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015298.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0004"/>
    <dbReference type="EnsemblBacteria" id="ADD39727">
        <property type="protein sequence ID" value="ADD39727"/>
        <property type="gene ID" value="Snas_0004"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0004"/>
    <dbReference type="eggNOG" id="COG1195">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040267_1_1_11"/>
    <dbReference type="OMA" id="GESWSYA"/>
    <dbReference type="OrthoDB" id="891841at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00365">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001238">
        <property type="entry name" value="DNA-binding_RecF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018078">
        <property type="entry name" value="DNA-binding_RecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042174">
        <property type="entry name" value="RecF_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32182:SF0">
        <property type="entry name" value="PTHR32182:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00611">
        <property type="entry name" value="recf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00618">
        <property type="entry name" value="RECF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="SMC_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD39727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="378" mass="41353" checksum="D477E24E75CD6B49" modified="2010-04-20" version="1">MHVRRLELTDFRSYGHVDVELPEGPSVFVGPNGHGKTNLIESLGYLATGSSHRVTSDAPLVRAGCESATARAAIVHEGRELLAELTITPGKANRARLNRSPLPRSRDLIGALKAVVFAPEDLNLIRGEPEQRRRLLDELLIARHPRFAGVRADYDRVVKQRNALLRTAYLARKTGGRGNTDLHTLDTWDAHLAQHGADLLAGRLALIEDYTPYVVKAYEAVSAGRGRPRLSYHSALGENEPLSPDRDLLTARLSAALATARSREVERGTTLVGPHRDDLKLVLGDLPAKGYASHGESWSYALALRLGAAELLRDNGTAPVLILDDVYAELDSQRRERLAELVARAPQVLVTCAVAEDVPAQMSGGRYDIHDGEVRRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTX4</accession>
    <name>D3PTX4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015303.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0009"/>
    <dbReference type="EnsemblBacteria" id="ADD39732">
        <property type="protein sequence ID" value="ADD39732"/>
        <property type="gene ID" value="Snas_0009"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0009"/>
    <dbReference type="HOGENOM" id="CLU_1165263_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="238" mass="24873" checksum="F6AF5FBA3E9F5FC6" modified="2010-04-20" version="1">MSDKASEFITLMTAVKELLNEAGQQSNSAAGIADEAAELFAQGGNANSHTMMTQAAESARKVLTQVAGLVSTTDEAIAQAQQAKGNLHTSSSGSSGVREPVAKIGDPIEAPQGGPDDTSDHRAELKSADDDDEEMTRADRALRVMARNAGDVETVTKDIVQTASSMFRTYKEDKPGSGQPSRMATGQSEAQTQVPQPKISSDTPQGPSFEGMAVATVLGGVAAIQGIKALRSRQPKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3PTX5</accession>
    <name>D3PTX5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0010"/>
    <dbReference type="EnsemblBacteria" id="ADD39733">
        <property type="protein sequence ID" value="ADD39733"/>
        <property type="gene ID" value="Snas_0010"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0010"/>
    <dbReference type="HOGENOM" id="CLU_1785712_0_0_11"/>
    <dbReference type="OMA" id="DRANWED"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="148" mass="16679" checksum="0020A6CC0EDA2E40" modified="2010-04-20" version="1">MNARTKYRAMLRAGLVGDFDAAEQLGTELGEVAWNDSGLLVNALFVLAVQRKFDDDTDRDVIREFVRETLDDYKSADPPFKPLMTEGLIRSVLGEEELYPEIPKNEAIPVQTAIINKIVADARTSPDKVDELLDKAEKLADRWIQQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU17</accession>
    <name>D3PU17_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1253</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016534.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1253"/>
    <dbReference type="ESTHER" id="stanl-d3pu17">
        <property type="family name" value="DPP4N_Peptidase_S9"/>
    </dbReference>
    <dbReference type="MEROPS" id="S09.073"/>
    <dbReference type="EnsemblBacteria" id="ADD40963">
        <property type="protein sequence ID" value="ADD40963"/>
        <property type="gene ID" value="Snas_1253"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1253"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006105_2_1_11"/>
    <dbReference type="OMA" id="VTHMTPQ"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DPPIV_N" evidence="2">
        <location>
            <begin position="108"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="509"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="714" mass="76338" checksum="C295B72472BB0C79" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU33</accession>
    <name>D3PU33_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016550.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1270"/>
    <dbReference type="EnsemblBacteria" id="ADD40979">
        <property type="protein sequence ID" value="ADD40979"/>
        <property type="gene ID" value="Snas_1270"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1270"/>
    <dbReference type="eggNOG" id="ENOG5033A4B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168032_1_0_11"/>
    <dbReference type="OMA" id="ISEFRRW"/>
    <dbReference type="OrthoDB" id="1855340at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="93" mass="10753" checksum="C3D560AA77F8E6B3" modified="2010-04-20" version="1">MSYILIRQKFTDYTQWRASFDAMADERQRHGLRNVVVTRNRDDQDEVVVLFEITDPAAVREYLHGGDLKAAWKRGTVIPETNQVTFLDDAAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUC9</accession>
    <name>D3PUC9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3272</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018513.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3272"/>
    <dbReference type="EnsemblBacteria" id="ADD42942">
        <property type="protein sequence ID" value="ADD42942"/>
        <property type="gene ID" value="Snas_3272"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3272"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="TSSHATW"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="442"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="13"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="469" mass="48003" checksum="72B8B7B4D46D6D46" modified="2010-04-20" version="1">MTAPEPTLRDRAILSLACCGSFVVILDATIVSVALPDIRSALDMTSSTLPWVVNAYTLAFAGFLLLGGRLSDRYGQRRMFMLGMVVFTLARAAAGLADATWLLLAARAIQGLGGALLMPVTLSLLTTRFTTPTARAKALGTWSAVGAVAAASGPVIGGILTQWTGWRSVFLISLPVGVAAVVAGARLPRATALRDRSRVDVVGAAIATTGLVGTVYAVMRTATVGWTDATVLLPLAGGVALLGLFGWHQAGWARDPLVPLGIFRARAVSSGNTVMFLLGLGFFASPVLLSLYLQDVHGYSPFGAGMAYLPIGVAMFVGAQSAGRLLVRVGARRASVWCCGIATVGFAGVAAVAAARLDQPLWMLLPGVVFGFGAAASFTPVTVVATSSVPPRHNGVAAGLLNTVRQTSAAIGLGALSTVTAVVGATWHAAHPRSDATAALAHGYTAAFAASAGCLLVAAIAAAWAMPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUH0</accession>
    <name>D3PUH0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3317</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3317"/>
    <dbReference type="EnsemblBacteria" id="ADD42983">
        <property type="protein sequence ID" value="ADD42983"/>
        <property type="gene ID" value="Snas_3317"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3317"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1626056_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="163" mass="17634" checksum="D12D114D2F7347DC" modified="2010-04-20" version="1">MTAFAFRPMAEADLSDVVRWLPAGFDLAAARDKYLPWIRGEHPNHLTLILADGHPCGFAWHYRVGDHREYSLATGEPDAIGIDVIVGDPGVGDHAALLRQYLRQVVLTAHPDATRVISSPAADDLSAVRMLTGAGFTPLRDITVFPGEPAETLCAFTVGDTND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUM1</accession>
    <name>D3PUM1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018605.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3370"/>
    <dbReference type="EnsemblBacteria" id="ADD43034">
        <property type="protein sequence ID" value="ADD43034"/>
        <property type="gene ID" value="Snas_3370"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3370"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_2_1_11"/>
    <dbReference type="OMA" id="ANVEIDW"/>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="38"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="253" mass="26755" checksum="06CD2FDC37EC1971" modified="2010-04-20" version="1">MEPGQVWSLGDYATVGDRWSSAGISLARDLARPQIRFLDVACGPGAMALTAARTGAVATGLDASPSLLDHARARAAGTDIAWREADMTAMPFADASFDVVASAFGAMFAPDPSAMAAELRRVCAPGGTIAVLAWTPESPFGMLRTLASAYLPPEAAGPAIEDWGTPERVAAFFGTPVDTEVRVVDVRWPSLNQAVEEITTLTPGMVLVREALEADRTWPRLVDEVTASFTAAGVTDGSGYRLPVAYLRTTVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUN1</accession>
    <name>D3PUN1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3380"/>
    <dbReference type="EnsemblBacteria" id="ADD43044">
        <property type="protein sequence ID" value="ADD43044"/>
        <property type="gene ID" value="Snas_3380"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3380"/>
    <dbReference type="eggNOG" id="COG2318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097062_2_1_11"/>
    <dbReference type="OMA" id="ESFLDFH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007061">
        <property type="entry name" value="DUF664"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04978">
        <property type="entry name" value="DUF664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="144" mass="15699" checksum="1E9BB4B5641E2BD2" modified="2010-04-20" version="1">METLRGFLDYLRDSIAAKVDNAPDPQARAAAVPSGTNLLGLLNHVTFVERATFLGERVTDWKATFHASAEDGVAEVVARYRETVERANEVLDGCTDLGAPLPRQRPGRSAPSVRWALTHLIEETGRHAGHADILRELIDGSTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUU7</accession>
    <name>D3PUU7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020542.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5337"/>
    <dbReference type="EnsemblBacteria" id="ADD44971">
        <property type="protein sequence ID" value="ADD44971"/>
        <property type="gene ID" value="Snas_5337"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5337"/>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_1_1_11"/>
    <dbReference type="OMA" id="TNWFGDQ"/>
    <dbReference type="OrthoDB" id="1942521at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="1">
        <location>
            <begin position="61"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="338" mass="36847" checksum="07B9E4A438DA9392" modified="2010-04-20" version="1">MSTAPTSSASLWRRALLGLTLPLILALAACGGGAGTDAGGDFGVKIKHKYGTTTIDKKPSKVVALGLNDADTLLALGIQPVGVVDWFGERPYGAWPWAKELWKGKKPKIVGERDDYNMEKIAKLAPDLIVAQYSGMTKDQYKTLSKWAPVVAQPLGHEDYAAPWQAMAEPIAKAVGEEKKLDKLIDGIEDDFAAVREEHPEFGKLTAAVSEGYEKGKYVAFAADDPKMEFMTLLGFKPDDKIESEIEKGNNVVEFGSERLDLVDVDLLVWLTADEAAAKNVKNDKVYSELDVVKDGRDLFVPYEEGPKIGAAMSFNTVLSIPYAIEELVPQLEKKAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV00</accession>
    <name>D3PV00_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cation efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_5392</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5392"/>
    <dbReference type="EnsemblBacteria" id="ADD45024">
        <property type="protein sequence ID" value="ADD45024"/>
        <property type="gene ID" value="Snas_5392"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5392"/>
    <dbReference type="eggNOG" id="COG0053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073293_2_0_11"/>
    <dbReference type="OMA" id="NSTLGWW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070161">
        <property type="term" value="C:anchoring junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026765">
        <property type="entry name" value="Tmem163"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31937">
        <property type="entry name" value="PTHR31937"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0965">Cell junction</keyword>
    <keyword evidence="9" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD45024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="240" mass="24811" checksum="DFD301741C3B3C18" modified="2010-04-20" version="1">MATVSLTAERRAKLNKRCLHLAYATAGYNLAEGIVAVTAGAIASSTALLGFGLDSFVEVSSALVVIWQFRSKLPEAREKLALKLIAASFFALAAWITIDAVRSLLGQGEAEPSPVGIAIAAVSVIVMPALVWAKRRTGKELGSATVVADSVQTLLCTYLSGILLIGLVLNATLGWSWADPIAALVIAAVAIKEGVEAWRGEQCDDCAIPTGDGGQADACGCGPDCTDACCTGQKKDGETT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV18</accession>
    <name>D3PV18_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5410"/>
    <dbReference type="EnsemblBacteria" id="ADD45042">
        <property type="protein sequence ID" value="ADD45042"/>
        <property type="gene ID" value="Snas_5410"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5410"/>
    <dbReference type="HOGENOM" id="CLU_2332275_0_0_11"/>
    <dbReference type="OMA" id="NWRTIER"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="98" mass="10974" checksum="D566AF179A4CD91E" modified="2010-04-20" version="1">MLAAPVPARHAAATQPPRNMWRFKLVRYEDVSGVSGTGVVAVGVVCSDGSAWMRWDSSDPSSAMFDNWRTIERKHGHRGATELQWIDMPPNTFLHHET</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVJ5</accession>
    <name>D3PVJ5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrogenase assembly chaperone hypC/hupF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HupF/HypC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018680.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3445"/>
    <dbReference type="EnsemblBacteria" id="ADD43109">
        <property type="protein sequence ID" value="ADD43109"/>
        <property type="gene ID" value="Snas_3445"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3445"/>
    <dbReference type="eggNOG" id="COG0298">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159381_2_2_11"/>
    <dbReference type="OMA" id="HYPARVD"/>
    <dbReference type="OrthoDB" id="2031925at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019812">
        <property type="entry name" value="Hydgase_assmbl_chp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001109">
        <property type="entry name" value="Hydrogenase_HupF/HypC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35177">
        <property type="entry name" value="PTHR35177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01455">
        <property type="entry name" value="HupF_HypC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00445">
        <property type="entry name" value="HUPFHYPC"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00074">
        <property type="entry name" value="hypC_hupF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01097">
        <property type="entry name" value="HUPF_HYPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="83" mass="8912" checksum="AEA73A158C48F5E9" modified="2010-04-20" version="1">MCLGIPGRIVDVAQGRPRMGTVDFDGLRREACLEYVPEAETGDYVIVHVGFAISRVDEAEAARTLAVIRAIPDALATELGTEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVL6</accession>
    <name>D3PVL6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Pyruvate dehydrogenase E1 component subunit alpha</fullName>
            <ecNumber evidence="2 7">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pdhA</name>
        <name evidence="10" type="ordered locus">Snas_3466</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + H(+) + pyruvate = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10480"/>
            <dbReference type="Rhea" id="RHEA-COMP:10481"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="2 7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3466"/>
    <dbReference type="EnsemblBacteria" id="ADD43130">
        <property type="protein sequence ID" value="ADD43130"/>
        <property type="gene ID" value="Snas_3466"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3466"/>
    <dbReference type="eggNOG" id="COG1071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029393_5_0_11"/>
    <dbReference type="OMA" id="YRSHGFT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017597">
        <property type="entry name" value="Pyrv_DH_E1_asu_subgrp-y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03182">
        <property type="entry name" value="PDH_E1_alph_y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 7 10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="E1_dh" evidence="9">
        <location>
            <begin position="18"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="35850" checksum="06CB1DEF078CDDE7" modified="2010-04-20" version="1">MTAHPEVDAGHRRELLHQMLRIRRFEERCAELYSATKIRGFVHLCIGEEAVAVGVHKALADDDAVVSTYREHGHALAKGITMDAVMAEMYGKATGCSHGRGGSMHLFDRDARFYGGNAIVGGGLPLAVGLALADTRLGRRQVTACFFGDGAVAEGEFHESLNLAALWRLPVLFCCENNQYAMGTPLRREHANTDLGARAVGYGMRSMEVDGMDVLAVEAAAHEAVAHIGRHREPVFLELRTYRFRAHSMYDPDRYRDKTEIESWKRRDPIPALAASLRATADLSDSDMDKMESEVTAEIDGAVAAAEAAPVEPESELTRHVYTERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVP3</accession>
    <name>D3PVP3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018728.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3494"/>
    <dbReference type="EnsemblBacteria" id="ADD43157">
        <property type="protein sequence ID" value="ADD43157"/>
        <property type="gene ID" value="Snas_3494"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3494"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_540671_0_0_11"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="379"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="505" mass="54506" checksum="811B11CB6EDF8E3E" modified="2010-04-20" version="1">MSPEVTSDRLRLARRLLGAGNPAGAVALVDEIDADTDDAAERAWALLVRMAAVIGLEWTNEYASTVDRAHAAVRAFGDVTALASFHALAALIANTMGSIEQCVTHLIKSSRTLNRLEQPQWEAAVAWHNIAVAYSYVGFHGHATQAASQARDLAAATGMDWRGRLPEVQVRHALSLDHQGDTDGCVRILRALLSMAERLPPREDGLPGIGTMDIPWIGYAAARLTVLGEATTVDALRCLAAGSDDAWTADLNQLGRICLSIHEGETDRARRLLDNATAAAAVLSPAEVPRLRALSHLADGDTRSAWRAEREAFAIDVARTDQLRRLVVDGMTARLDHEELRRTVSGYADDARTDPLTGLPNRVHLGEYIDGLVERAESGVVAVVEVVVEHPDSTSAQSGDDAVLQRVADSLMRIMRSGDFVARYGGAEFVLVLPGTKLSQTADVGRRVTRELDKEDWDLVSSGGTPHFDLGWADLSGNHEPGRRITGANTKADRIVARARNACAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVV9</accession>
    <name>D3PVV9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020651.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5448"/>
    <dbReference type="EnsemblBacteria" id="ADD45080">
        <property type="protein sequence ID" value="ADD45080"/>
        <property type="gene ID" value="Snas_5448"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5448"/>
    <dbReference type="eggNOG" id="COG1672">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1915812_0_0_11"/>
    <dbReference type="OrthoDB" id="801313at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="132" mass="14309" checksum="207D93A5E0121668" modified="2010-04-20" version="1">MRRPVAASAGSREGQLPSGTLSPILRQLVEDKRVLARDEPLSTRPGKPTLYRIADAAPVAKRVEFAGSIKWLESAFDGHDLSDLINAVANLPGFRRDSGLLIVSLSGVDERADPRPVDVVWGPGDVLDAWRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVZ0</accession>
    <name>D3PVZ0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplU</name>
        <name evidence="6" type="ordered locus">Snas_5480</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">This protein binds to 23S rRNA in the presence of protein L20.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Contacts protein L20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020682.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5480"/>
    <dbReference type="EnsemblBacteria" id="ADD45111">
        <property type="protein sequence ID" value="ADD45111"/>
        <property type="gene ID" value="Snas_5480"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5480"/>
    <dbReference type="eggNOG" id="COG0261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061463_3_0_11"/>
    <dbReference type="OMA" id="HRQEITR"/>
    <dbReference type="OrthoDB" id="1949059at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="L21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="L21p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_L21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018258">
        <property type="entry name" value="Ribosomal_L21_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="PTHR21349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="SSF141091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01169">
        <property type="entry name" value="RIBOSOMAL_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD45111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="104" mass="11211" checksum="C4440F91A20E7C9F" modified="2010-04-20" version="1">MYAIVKTGGKQYKAVEGDVLEVEKLAGEPGDTVTLPAVLLVDEGKVTTDAKALSGVTVNGELVDHFKGPKIKIHKFKNKTGYHKRQGHRQQLTRVKVTGISGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW29</accession>
    <name>D3PW29_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Succinate dehydrogenase and fumarate reductase iron-sulfur protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5519</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020721.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5519"/>
    <dbReference type="EnsemblBacteria" id="ADD45150">
        <property type="protein sequence ID" value="ADD45150"/>
        <property type="gene ID" value="Snas_5519"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5519"/>
    <dbReference type="eggNOG" id="COG0479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044838_2_0_11"/>
    <dbReference type="OMA" id="KYDPLVW"/>
    <dbReference type="OrthoDB" id="1605514at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="3">
        <location>
            <begin position="5"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="254" mass="29309" checksum="14A5D44C3BBAE496" modified="2010-04-20" version="1">MSTQRHFRVWRGDDEGGELTDFTVEVNEGEVVLDVIHRLQATQAPDLAVRWNCKAGKCGSCSAEINGRPRLLCMTRMNLFGDDETITVTPVRTFPVIRDLVTDVSYNYDKARAMPAFAPPSDLEPGEYRMQQVDVERSQEFRKCIECFLCQNTCHVVRDHEENKPDFSGPRMFIRAAELDMHPLDERDDRKELAQAEQGLGYCNITKCCTEVCPEHIKITDNAIIPMKERVVDRKYDPVTWLGRKIFRRDQVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW32</accession>
    <name>D3PW32_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4185 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5522</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020724.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5522"/>
    <dbReference type="EnsemblBacteria" id="ADD45153">
        <property type="protein sequence ID" value="ADD45153"/>
        <property type="gene ID" value="Snas_5522"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5522"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047934_1_0_11"/>
    <dbReference type="OMA" id="YSPIALH"/>
    <dbReference type="OrthoDB" id="875398at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025442">
        <property type="entry name" value="DUF4185"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13810">
        <property type="entry name" value="DUF4185"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049501" description="DUF4185 domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4185" evidence="2">
        <location>
            <begin position="53"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="371" mass="40916" checksum="ACDA4ACCE5B0EFB0" modified="2010-04-20" version="1">MKRSTLLKAGLGAVGGAAVLGGGALAYASGDSSGKKETRAGVTVKKIADLTGNDNTIKFGVNGTDLGIPVVTPQGKNLYIFGDSYEGPKPTPEDANWRSPIGLFSGTTDLPSGLVFDGAIGGEVARQLWDYQHNNGEFSTVLPSDIITIGDTMFLQVMVHGEKLGDVLRSEIWSSKDEGESWQDTQARWAGDVHGGRMQQLTWALDDDDMVYVFSSRFDRSVGFILHRVHKDAIADTNAYEWWGWDEGTKKWDWNIGTPGEVWTQPTGEMCLRRLEGKWVMTWFNASQGKESIDGLVFDKPNDDLTKAHHKQLILNTPWGQEDDSHVAQLYGGYIIPGSTINDLHLVVSQWKTDDHSVYRSMQHRVQGLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWH9</accession>
    <name>D3PWH9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018772.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3539"/>
    <dbReference type="EnsemblBacteria" id="ADD43201">
        <property type="protein sequence ID" value="ADD43201"/>
        <property type="gene ID" value="Snas_3539"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3539"/>
    <dbReference type="eggNOG" id="COG0394">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081551_1_0_11"/>
    <dbReference type="OMA" id="CDNVHES"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="3"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="228" mass="24994" checksum="10045392BEE83E0E" modified="2010-04-20" version="1">MFVESDDTERRARVHAALGEPSRLRIVDALAVADASPHELERLVGMPSNLLAHHLKTLVDAGVVTRSRSEADRRRTYLRLVPEAVASLAVLPRVVASRVVFVCTRNTARSQLAKVLWPQYSPVPAASAGTNPAARVHPRAVAVARRHGLRLPLGETHHVSDVVDDGDLVIAVCDNVHESLSVDIPRWHWSIPDPVAVDTDEAFELAFADIDRRIDRVAPLLTCRTGMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWR0</accession>
    <name>D3PWR0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3622</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018853.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3622"/>
    <dbReference type="EnsemblBacteria" id="ADD43282">
        <property type="protein sequence ID" value="ADD43282"/>
        <property type="gene ID" value="Snas_3622"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3622"/>
    <dbReference type="eggNOG" id="COG1172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028880_0_2_11"/>
    <dbReference type="OMA" id="YTQDFVK"/>
    <dbReference type="OrthoDB" id="1254678at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="334" mass="34419" checksum="E9CD242250B49B94" modified="2010-04-20" version="1">MTKTSLATPPPVALTEPWSWKRLLTAPVFGPCVALVLATVFFATQSATFLTGPSLSLILQQVMVVGTLAIGQTLIILVAGIDLSVGTIMAFGSIVMAKLAVDSGLPWPVAVGAGIATCTVFGLVNGLLVTRIKLPPFIVTLGMLNIAYALTHMYSAEETVTNLPAGMTALGETFAIGDTRVTYGSVLMLVLFGVVAYILGGTAWGQRLYAVGSNAEGTRLTGIPVDRVRLAAFTAAGAIYGIAALLLIARTGVGDPKVGLTENLESITAVVLGGTSLFGGRGAVLGTLVGVLIVGVFRSGLQQMGVGATPQILVTGILVILAVTVDQLARRRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWT5</accession>
    <name>D3PWT5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallothiol transferase FosB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018878.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3649"/>
    <dbReference type="EnsemblBacteria" id="ADD43307">
        <property type="protein sequence ID" value="ADD43307"/>
        <property type="gene ID" value="Snas_3649"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3649"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142293_0_0_11"/>
    <dbReference type="OMA" id="YEVMSPA"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="123" mass="13231" checksum="F5B65EBD5DB83835" modified="2010-04-20" version="1">MSIVLNHTIVPASDKQAAATFFAELMGLAVSAPSGPFAPVAVNDDLTLDFDDRADVAPGHYAFLVDDDTFDAVLHRLSTWPAVDYGSGVENGWDRRINHLGGGRGVYVRDPNGHSYELFTAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWX5</accession>
    <name>D3PWX5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5568</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020770.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5568"/>
    <dbReference type="EnsemblBacteria" id="ADD45199">
        <property type="protein sequence ID" value="ADD45199"/>
        <property type="gene ID" value="Snas_5568"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5568"/>
    <dbReference type="eggNOG" id="COG4912">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061369_0_1_11"/>
    <dbReference type="OMA" id="RLQWAMN"/>
    <dbReference type="OrthoDB" id="1933111at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014825">
        <property type="entry name" value="DNA_alkylation"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08713">
        <property type="entry name" value="DNA_alkylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="24830" checksum="6AB66E246758661C" modified="2010-04-20" version="1">MAETTVAEVTAELAALEDPKARAVNEKHGDDHGVNLSRLRALAKRLKTQQELARQLWATDDTAAKLLALLICRPKAFERDELDAMLRQARTPKVHDWLINYVVKKNPHTEELRAAWFTDPDPVVASAGWALTADRVARNPEGLDLDTLLDLIEAKMKDAPDRLQWAMNTCLAQIGIEHAEHRARAIDIGERLEVLKDYPTSPGCTSPFAPIWITEMVRRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX78</accession>
    <name>D3PX78_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016912.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1638"/>
    <dbReference type="EnsemblBacteria" id="ADD41341">
        <property type="protein sequence ID" value="ADD41341"/>
        <property type="gene ID" value="Snas_1638"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1638"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_2_3_11"/>
    <dbReference type="OMA" id="YCFQPMM"/>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="47"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="269" mass="28789" checksum="FF2F74136688A681" modified="2010-04-20" version="1">MNSFDERMRHNYAGRAEIFERTFGKLCAYPVPTVLDAVGVAAGTRLLDVGCGTGSVAAAARDRGAAVTAVDPEQSMVEIASRRVPEATVLAGELPRLPFEDDAFDAVVANFVLNHVGDPLAALGELRRVLRPHGRLGLTIWPQPPTPLHGLWPRVFEAAGVDANANVARLAADKDFERTEAGLAGLLADAKFVEVETRTVPWKHRVDPELWWSGPAAGLASFGQVLAAQTPETVARIKREYDRLSAEFRVATGELALPTAALLAVAVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXB2</accession>
    <name>D3PXB2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016946.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1673"/>
    <dbReference type="EnsemblBacteria" id="ADD41375">
        <property type="protein sequence ID" value="ADD41375"/>
        <property type="gene ID" value="Snas_1673"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1673"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_11"/>
    <dbReference type="OMA" id="VKPPFDI"/>
    <dbReference type="OrthoDB" id="831053at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="316" mass="32915" checksum="74DA62BD158FD372" modified="2010-04-20" version="1">MRAIRFHQPGGPEVLTVDEVADPVPTGDQLLINVTASGVNYADIERVAGVYDPPKVLPHILGGEVVGRTADGRRIAGLTRGGGGYATRAAVEAHHAVEVPDPIDDGQALAVLVQGLTAWHLLRSAARLTEGETVVVHAAAGGVGSLLVQLARHFGAGRVIAVASTPEKRELALKLGADVAIDADPDTYVDRVLAATGGAGADVVLDANAGPILAAAVEVLAPFGRVYSYGDAGNEGRGLVDPEKLAERNAAVGGFWIGPVLNRPEIFAGPVADMFGLITSGALNPLVSAEYPFDEVKRALTDMRERRTTGKVWLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXH3</accession>
    <name>D3PXH3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1738</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017007.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1738"/>
    <dbReference type="EnsemblBacteria" id="ADD41436">
        <property type="protein sequence ID" value="ADD41436"/>
        <property type="gene ID" value="Snas_1738"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1738"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="IYYKRQD"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="303" mass="32114" checksum="4CDAB6AC90988126" modified="2010-04-20" version="1">MIDIRGLVKRYRATTAVDDLSFTVEPGSVTGFLGPNGAGKTTTMRILLGLAAATEGEALVKGERYPRLSEPTRSVGALLDAGDVHPGRSALSHLRAIAYANRIGDERVSAVLEQVGLAGVARKRVGKFSLGMKQRLGIAAALLGDPDVLILDEPVNGLDPDGVRWIRELTRGLADEGRTILISSHLMSEMELTADRLIIIARGKLIADTSVSELAERFQRGISVRSPRADELAQVLEAEGAAVAREADALLVNGLDVAAIGDLAAGKGIALHEVAPRRTTLEDAYMALTSDSLQFAARPGRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY86</accession>
    <name>D3PY86_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Small GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1755</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017024.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1755"/>
    <dbReference type="EnsemblBacteria" id="ADD41453">
        <property type="protein sequence ID" value="ADD41453"/>
        <property type="gene ID" value="Snas_1755"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1755"/>
    <dbReference type="eggNOG" id="COG0480">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002794_4_2_11"/>
    <dbReference type="OMA" id="TPASWPI"/>
    <dbReference type="OrthoDB" id="466142at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="5">
        <location>
            <begin position="1"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="662" mass="71590" checksum="27EF1154A6D93059" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYE1</accession>
    <name>D3PYE1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017079.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1812"/>
    <dbReference type="EnsemblBacteria" id="ADD41508">
        <property type="protein sequence ID" value="ADD41508"/>
        <property type="gene ID" value="Snas_1812"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1812"/>
    <dbReference type="HOGENOM" id="CLU_1853986_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="138" mass="15364" checksum="359AA630681EC119" modified="2010-04-20" version="1">MAASHAYTLPADDPHAVAEAVGRAAAGSVVRLVRGDEQVADITPPDPDSAFRPLLAEIEARANAICAAHPDPEDLEHWQRAERLHHRWRTTGRLPMAEDYAIELRKLDILTEQQLLDQADAMVRADEQALVFYPLPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYI5</accession>
    <name>D3PYI5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1856"/>
    <dbReference type="EnsemblBacteria" id="ADD41552">
        <property type="protein sequence ID" value="ADD41552"/>
        <property type="gene ID" value="Snas_1856"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1856"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_688510_0_0_11"/>
    <dbReference type="OMA" id="WQAEIGN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="216"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="383" mass="42720" checksum="0FDCC5C37A33A010" modified="2010-04-20" version="1">MEPVNIAIEGQGDNLPPLLLRPPGPADVTAVAELFNDPQTSQWSLVPKPFTEAHAKTFLEIARRDWNRDSPRWLICDADGSKVLGTVALRRHPRQTWEVVFHTAPWARRRQVALRAVHAAVRFGFATLSARRLEWNAIVGNHLSRLIAIRLGFQLEGVARAMADQRGTRVDQWIGSLLPGELRELDDPPPDYDVDRKRALLFCGGQPSLDTAVEGLRLRPLHADDIELIVEACQDPETARWTTVPQPYERQHAEYFVDQVGAGSWRQGIAVIFALADAEDRFCGGIDLRLNSADKRVGEVGFSSAPWSRGRGYMTAALRAVCDFGFDSLDLERVEWKAFVGNVASRRVAEKAGFTMEGTLRSDVLARGERVDSWVAALLRGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYQ5</accession>
    <name>D3PYQ5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">o-succinylbenzoate synthase</fullName>
            <shortName evidence="3">OSB synthase</shortName>
            <shortName evidence="3">OSBS</shortName>
            <ecNumber evidence="2 3">4.2.1.113</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">4-(2'-carboxyphenyl)-4-oxybutyric acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">o-succinylbenzoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">menC</name>
        <name evidence="5" type="ordered locus">Snas_3832</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate = 2-succinylbenzoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10196"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18325"/>
            <dbReference type="ChEBI" id="CHEBI:58689"/>
            <dbReference type="EC" id="4.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 4/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.113" evidence="2 3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019059.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3832"/>
    <dbReference type="EnsemblBacteria" id="ADD43488">
        <property type="protein sequence ID" value="ADD43488"/>
        <property type="gene ID" value="Snas_3832"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3832"/>
    <dbReference type="eggNOG" id="COG4948">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030273_4_4_11"/>
    <dbReference type="OMA" id="CRIINIK"/>
    <dbReference type="OrthoDB" id="951991at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043748">
        <property type="term" value="F:O-succinylbenzoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03317">
        <property type="entry name" value="NAAAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01933">
        <property type="entry name" value="MenC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010197">
        <property type="entry name" value="OSB_synthase_MenC_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48073:SF5">
        <property type="entry name" value="PTHR48073:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01928">
        <property type="entry name" value="menC_lowGC/arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="4">
        <location>
            <begin position="142"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="370" mass="39832" checksum="1E3F51B5CAA4BAC1" modified="2010-04-20" version="1">MRITGARLHRVHMPLVAPFRTSFGTETVREFVLLRLETDNGVGWGECVADATPLYSSEYLDAANQVMAEFLLPRLADRDTITAPQVAEALSGFKGHPMAKSCVEMAVLDAGLRSCGMSFADYLGGVHATVPVGVSVGIMDSIHELLDAVDGYLKDGYRRVKLKIEPGWDVEPVREVRERFGDDVDLQVDANAAYRLSDARQLARLDDFDLLLLEQPLAADDLRGHAELAWRLTTPICLDESITSARSAADAIALGAASMVNIKPGRVGGYLEARRVHDVCAANGVGVWCGGMLETGLGRAANLALAGLPGFVLPGDISASTRYYARDITEPFELEDGCLRVPTGPGLGVEPIGEALAEFSVSTQWIDFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYR1</accession>
    <name>D3PYR1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mg2 transporter protein CorA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3838</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019065.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3838"/>
    <dbReference type="EnsemblBacteria" id="ADD43494">
        <property type="protein sequence ID" value="ADD43494"/>
        <property type="gene ID" value="Snas_3838"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3838"/>
    <dbReference type="eggNOG" id="COG0598">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007127_0_2_11"/>
    <dbReference type="OMA" id="MVEFKRA"/>
    <dbReference type="OrthoDB" id="822653at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="SSF143865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="SSF144083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="321" mass="36229" checksum="5B924350918074B9" modified="2010-04-20" version="1">MLTWWRCDAEGIRPGEKSVDFATVPDSLPPGGFAWVELTEPDAAELERLVTVLRLPPFVIHDAISAHRRPRLDAYGDVMSMVVKSVWYLDGTSDVETGDVTFLLNRWLLVTVRHGDGDPMPDARARLEHNPKLLRLGTRGAAYAVVGTMVDTYLKVSEEIETDVTELERAVFSPGRVKRVEQLYSLQREVLEFREAVQPMDVIADELLSHHDRRDAVTPFVRTLAHRVKRAGDSAARSENLLNAILQAHLGQIGMWQNEDMRKISAWAAIIAAPTMIAGIYGMNFKHMPELNWVVSYPAVLLLMAVICWLLHRGFKRNGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYS4</accession>
    <name>D3PYS4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alanine dehydrogenase/PNT domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019078.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3851"/>
    <dbReference type="EnsemblBacteria" id="ADD43507">
        <property type="protein sequence ID" value="ADD43507"/>
        <property type="gene ID" value="Snas_3851"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3851"/>
    <dbReference type="eggNOG" id="COG3288">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003376_2_1_11"/>
    <dbReference type="OMA" id="YFPMLMT"/>
    <dbReference type="OrthoDB" id="464096at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="2">
        <location>
            <begin position="7"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_C" evidence="1">
        <location>
            <begin position="151"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="380" mass="39417" checksum="D3582D8DFBCE0EBA" modified="2010-04-20" version="1">MVSTTVGVVKEPSPGESRVSLIPEQVSRLKTSGLDVVVESAAGHGAHIADEEYTAAGAAVVAVDELYERADIITRVSALSAADAKRLRDGQLLAGLLEPLRYLDIMRELAANNITTASLDMLPRTLSRAQSMDVLSSQANIAGYKAAVLAADNYGRYFPMLTTAAGTSPPANALILGTGVAGLSAIGTARRLGAVVTAYDVRPESRAEVESLGARFLELETTVAASGTGGYARALTEDERAAQQRELSTRIGKFDVVITTAKVPGKTPPLLVTREALAGMRPGSVVVDLAASDLGGNVAGSEPESTIDIDGVRVIGAGNLPSVMASAASAAYSRNMFAFLSHLIDEGSVAIDLDDEINAGVIITHNRSFVNKIVADAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ81</accession>
    <name>D3PZ81_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heavy metal transport/detoxification protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021081.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5882"/>
    <dbReference type="EnsemblBacteria" id="ADD45510">
        <property type="protein sequence ID" value="ADD45510"/>
        <property type="gene ID" value="Snas_5882"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5882"/>
    <dbReference type="eggNOG" id="COG2608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134973_13_1_11"/>
    <dbReference type="OMA" id="HCVNAIT"/>
    <dbReference type="OrthoDB" id="2061355at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000428">
        <property type="entry name" value="Cu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00944">
        <property type="entry name" value="CUEXPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="2">
        <location>
            <begin position="3"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="69" mass="7085" checksum="83084C42B8D0CE4A" modified="2010-04-20" version="1">MTTQTYTVTGMTCQHCVNAVTEELSGIEGVTGVDVDLTSGRVTVTSQSAVDDKSVAEAVDEAGYELAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZJ4</accession>
    <name>D3PZJ4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017239.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1972"/>
    <dbReference type="EnsemblBacteria" id="ADD41668">
        <property type="protein sequence ID" value="ADD41668"/>
        <property type="gene ID" value="Snas_1972"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1972"/>
    <dbReference type="HOGENOM" id="CLU_696201_0_0_11"/>
    <dbReference type="OrthoDB" id="912543at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="396" mass="43561" checksum="16290487A728616A" modified="2010-04-20" version="1">MTTFDKAAYDGILDEIEKYLGYLKGNELVFEYMEAVREKVEATGRPPVTQKNYTTPCANPEFTYQPLYHLPTLDGGEVPRELEKKIHANADACWHNGKTWAAGIAGQARAITEQITSPDVAELETALTALKEKVMQPLELLIDSNADLPGPYRIPLPDGENSLDGDWANLKNFTNTWHGTAAEEFRTLHDKLNSYVGMYAYFAATAALELAAATDVIASAQQGLVMSVKDVRKTLVAQLKEWHDTDSPPEDEELSVFMLIVELLPITKVYKGARLIVEAVDDPKVVIGVLADIKRTIVGKSWKGIENEGKEPFEAANSEVVLKSLTTMLRQTYLHDFMEALSELSAAPDGSLNFVRSLQDTGMWAPPTVPRGSVLRDGDAYPPDACPPYGSTGSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZM0</accession>
    <name>D3PZM0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1998</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1998"/>
    <dbReference type="EnsemblBacteria" id="ADD41694">
        <property type="protein sequence ID" value="ADD41694"/>
        <property type="gene ID" value="Snas_1998"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1998"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029927_4_0_11"/>
    <dbReference type="OMA" id="RTSVAHW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="460" mass="50448" checksum="014D11945A02694C" modified="2010-04-20" version="1">MNPLRTVNFRLQAFMDEAGLNGDGLARSIRAVGDQVGLSLRCGRATVGQWLRGRNPRPPIPTLAAEALSRALDRDVSPAHLGFEADSSEDLAFWHERSVAGQLQVLHQLDNVSGPCQNPRVYRVAALRPPIWDEPPPDLARPSTTRPLGTGRLGRAEVEDAETMLRLFGQADSRAGAGHVRPALARYLADQIRVWTTAPARDDIRRELLAIAARLAYLCGFLFFDDELHGTAQRYYHVAAELAREAGRPGPHAMALRALSVQARLLGHPRPALALAEASLSDAPTDCDPLTRAFLTGQLAVAHAADGDRYRALRQLSATEHWFAKGCDRVDAPMAYNHASLAHQKAAVLALLHQRPQAIAALELSVRQRPAHERRSRAITKARLAELQLSHGHLEQATATWHTFLDDYRCILSGRARSALAIMRASLRPYKNNRLAGEVLRRALALPYVGLGGGQSMVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZT2</accession>
    <name>D3PZT2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019190.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3967"/>
    <dbReference type="EnsemblBacteria" id="ADD43619">
        <property type="protein sequence ID" value="ADD43619"/>
        <property type="gene ID" value="Snas_3967"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3967"/>
    <dbReference type="eggNOG" id="COG0433">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011350_0_0_11"/>
    <dbReference type="OMA" id="AVDQIDT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008571">
        <property type="entry name" value="HerA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002789">
        <property type="entry name" value="HerA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42957">
        <property type="entry name" value="PTHR42957"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01935">
        <property type="entry name" value="DUF87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="56"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="657"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1023"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1030"/>
            <end position="1046"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1046" mass="114393" checksum="B3FC72D5EDB6176D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZW0</accession>
    <name>D3PZW0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Imidazoleglycerol-phosphate dehydratase</fullName>
            <shortName evidence="5">IGPD</shortName>
            <ecNumber evidence="5">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hisB</name>
        <name evidence="6" type="ordered locus">Snas_3995</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019218.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3995"/>
    <dbReference type="EnsemblBacteria" id="ADD43647">
        <property type="protein sequence ID" value="ADD43647"/>
        <property type="gene ID" value="Snas_3995"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3995"/>
    <dbReference type="eggNOG" id="COG0131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044308_3_0_11"/>
    <dbReference type="OMA" id="ARHGLFD"/>
    <dbReference type="OrthoDB" id="1278103at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4 5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="22107" checksum="F4A426D0FE3B2428" modified="2010-04-20" version="1">MSRTGTVSRTTKETSVHVSLDLDAPQGIIEVSTGVGFFDHMLNQLGKHGAMDLTVRTEGDLHIDAHHTMEDTAIALGEAYRQALGDCRGVRRFADATVPLDEVLARAVVDLSGRPYVVHEEPLELAPTINTDYPTSMTRHILESFGHHARITLHVSVLRAANHGQRPDAHHVVEAQFKALARALRSASELDGLDEVPSTKGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZW8</accession>
    <name>D3PZW8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4003</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019226.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4003"/>
    <dbReference type="EnsemblBacteria" id="ADD43655">
        <property type="protein sequence ID" value="ADD43655"/>
        <property type="gene ID" value="Snas_4003"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4003"/>
    <dbReference type="eggNOG" id="ENOG5032YYX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082043_0_0_11"/>
    <dbReference type="OMA" id="RYHLAGC"/>
    <dbReference type="OrthoDB" id="1919338at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="203" mass="21582" checksum="0DD069CE2C293B53" modified="2010-04-20" version="1">MIVGSLLLLLTGVVLLVMGLVRGDDTYLVGTIIASLLAAVCLYGASRRTKSRRAAASRTRARRPARSDEAETDSRLRGRADDTAVVPRSRDDAPVAESGPDEADTPAESGGRPTVDMDVETEAVPSDEPAEVPMSSVEAAALMRMDAEVMVVDGRPRFHLGGCVHLVGRDAEPLPAYEAVELGFGACALCRPAQSLLREPTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q006</accession>
    <name>D3Q006_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-hydroxyacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.35</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5907</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.35" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021106.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5907"/>
    <dbReference type="EnsemblBacteria" id="ADD45535">
        <property type="protein sequence ID" value="ADD45535"/>
        <property type="gene ID" value="Snas_5907"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5907"/>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_2_0_11"/>
    <dbReference type="OMA" id="KGVNYPK"/>
    <dbReference type="OrthoDB" id="862072at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="3">
        <location>
            <begin position="6"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="2">
        <location>
            <begin position="184"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="1">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="287" mass="30695" checksum="EB292349EEE15D9D" modified="2010-04-20" version="1">MSQRFAVAGAGTMGAGIAYVAAGSGYEVTLVEIDEARGRAAVDGIRDWARKAVERGRSTSEEAAATLERLRLVTEFTDVDPEPAVFVEAVPERPELKHQVLAAAEQLRPELLASNTSSISIDSLAARLEAPERFCGLHFFNPVYAMALLEIVIGDKTSDASREAALAVARRLGKEPVVVRDSPGFATSRLGNALGLEAIRMLESGVASAADIDKAMSLGYRHPMGPLELSDVVGLDVRLDIARSLQAAYGDRFEPPRTLIDLVAQGKLGKKSGQGFYTWVDGKKVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q019</accession>
    <name>D3Q019_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021119.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5920"/>
    <dbReference type="EnsemblBacteria" id="ADD45548">
        <property type="protein sequence ID" value="ADD45548"/>
        <property type="gene ID" value="Snas_5920"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5920"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089258_3_0_11"/>
    <dbReference type="OMA" id="APMHGYE"/>
    <dbReference type="OrthoDB" id="1706427at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="3">
        <location>
            <begin position="6"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="119"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="198" mass="22522" checksum="F8EBD55F1FD5E22C" modified="2010-04-20" version="1">MLELAVLGLLHDSPMHGYELRKRLTTLLGAFRATFSYGSLYPTLRKMRERGWIVEDAPAPAGEAPPLTGRRGRISYRLTPEGKERFAELIATACPEAFEDTGFGVHFAFFSRCEPAVRLRVLEGRRRRVEERRETLRDTVDRATERLDAYSLELQRHGLEACEREVRWLNEIIASEQAGRPPSVSFGDDTNETPDSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q068</accession>
    <name>D3Q068_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021168.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5970"/>
    <dbReference type="EnsemblBacteria" id="ADD45597">
        <property type="protein sequence ID" value="ADD45597"/>
        <property type="gene ID" value="Snas_5970"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5970"/>
    <dbReference type="eggNOG" id="COG4320">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032121_1_0_11"/>
    <dbReference type="OMA" id="HADPWLG"/>
    <dbReference type="OrthoDB" id="571864at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018721">
        <property type="entry name" value="DUF2252"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39441">
        <property type="entry name" value="PTHR39441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10009">
        <property type="entry name" value="DUF2252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="436" mass="48564" checksum="2647D8D32BCA6189" modified="2010-04-20" version="1">MTANAAERTEHIIDVFLTEFGELMKADPNAFHRKFRKMAASPFAFYRGSACLFYSDVKNDDSTFLDEKTSRVWMHGDLHAENFGTYMNANGVLVFNVNDFDEAYVGPFTWDLKRFAASVALIGYAKALSDDDITQLVTAFARSYLAELRLIAAHGDDAIGELTLDTSDGELRGVLQKARLGSRLHLLNKQTEIVDYERKFMLGGGAYPVDEAQRAKVRDAFAQYLTTLPASRHQRPTELQIKDFALRKGVGIGSAGLPSYNVLLEGNSQALENDIIVYMKQAQVPAVSRVIDDERITKYFRHQGHRTAESQHALQSYADPWCGYTELDGVGQFCAEVSPYAADLDWSNLDEPEEMAPVVAYLGRAVARMHSVADDDSEHGLVNYSTEDAIAAAIGDDDAGFTSLLVDFAHRYGQRARADHQLFVDLFRNDRLPTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q088</accession>
    <name>D3Q088_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45617">
        <property type="protein sequence ID" value="ADD45617"/>
        <property type="gene ID" value="Snas_5991"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5991"/>
    <dbReference type="HOGENOM" id="CLU_3189276_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="46" mass="5018" checksum="9382CF6A86DB7B56" modified="2010-04-20" version="1">MSSPRKDSLRSIAVMIGLFVFVIAAVVIVLTFGLSLLTDDFVAQFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0F9</accession>
    <name>D3Q0F9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015394.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0102"/>
    <dbReference type="EnsemblBacteria" id="ADD39823">
        <property type="protein sequence ID" value="ADD39823"/>
        <property type="gene ID" value="Snas_0102"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0102"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_2_2_11"/>
    <dbReference type="OMA" id="TAMERMI"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="192" mass="20932" checksum="1CBA98C68DEE2F54" modified="2010-04-20" version="1">MEPGLRERKKQRTRDALVAAAVDLFQRQGYEHTTVAQIAEAAELSTRTFFLHFPTKEDVLLANTDRRIAAGVQAITTHRANTPLATVLLTAMERMIDDADPSDLTQLRAQLLVRTPALQARLFQRLFSGQTALIDALTTTFDVDRVEAAARVGAMIGAVNAATLASLDQGDPPSRQREAMTRAARLAVTPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0K0</accession>
    <name>D3Q0K0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoprenyl transferase</fullName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2041</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017307.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2041"/>
    <dbReference type="EnsemblBacteria" id="ADD41736">
        <property type="protein sequence ID" value="ADD41736"/>
        <property type="gene ID" value="Snas_2041"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2041"/>
    <dbReference type="eggNOG" id="COG0020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038505_1_2_11"/>
    <dbReference type="OMA" id="PRTEGHK"/>
    <dbReference type="OrthoDB" id="1630604at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="36"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="80"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="209"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="262" mass="29689" checksum="34D013ADD6D3D75D" modified="2010-04-20" version="1">MSRRQYSPPTPHPSGARPPAIPKDLIPKHVAVTMDGNGRWAKQRGLPRTDGHAAGEASLFDTIEGAIELGISTLSAYAFSTENWRRSPDEVRWLMGFNRDVIHRRRDELNAMGVRIRWAGRRPKLWRSVIKELEIAQEMSKHNDKITLQFCVNYGGRAEISDAAAAIARDAAAGKLNPDKVSEKTVAKYLYNPDLPDVDLFLRPSGEQRTSNFLPWQATYAELVFQDVLWPDFDRRHLWHACEVYASRDRRYGGAIPNPVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0W9</accession>
    <name>D3Q0W9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class II aldolase/adducin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019290.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4067"/>
    <dbReference type="EnsemblBacteria" id="ADD43719">
        <property type="protein sequence ID" value="ADD43719"/>
        <property type="gene ID" value="Snas_4067"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4067"/>
    <dbReference type="eggNOG" id="COG3347">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1105848_0_0_11"/>
    <dbReference type="OMA" id="FVGHTHP"/>
    <dbReference type="OrthoDB" id="1317575at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="7"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="254" mass="27081" checksum="271F79A218DD1EB7" modified="2010-04-20" version="1">MTTYTVADLTELSLTLGQANRDLVILAEGNTSVRLGPGRMLVKASGSTMPTASESDFVELETAPLLELISSESSSDDEIDAVLRAARIDPAGPRPSMEALLHAICLEEAGATVVAHTHPIAVNAILCSDRAETLVAGSLFPDQIVVMGRHNLLVPYADPGLALARSVRDGLRQHRARHGAPPKVVYLVNHGIFVLADSPTQALAITDMTVKSARILLGALSAGEPRYLSDADAERIDVRPDEVRRRERLAAVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q114</accession>
    <name>D3Q114_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4113</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019335.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4113"/>
    <dbReference type="EnsemblBacteria" id="ADD43764">
        <property type="protein sequence ID" value="ADD43764"/>
        <property type="gene ID" value="Snas_4113"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4113"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027555_0_0_11"/>
    <dbReference type="OMA" id="FDLCAQR"/>
    <dbReference type="OrthoDB" id="618655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07129">
        <property type="entry name" value="ALDH_KGSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044151">
        <property type="entry name" value="ALDH_KGSADH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="4"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="504" mass="52334" checksum="636FA92A0D5F54AE" modified="2010-04-20" version="1">MSVISSVNPRTGETFGEPFPPTSDVEVAALASDAAEAAPGFEALGRSGRAALLRAMGAALDARRGDIVAIADAETGLGEARLNGELTRTVYQLGLFADVIEEGSYLEAAIDHAADTPMGPGPDLRRMLVPLGPVAVFGASNFPLAFSVPGGDTASALAAGSPVIVKAHESHPATSQLTFEILRHALRDSGVDERVLGIVYGREAAAALVADPRVKAVGFTGSLRGGKALLDIINTRPEPIPFYGEMSSLNPVVLTEAALRERGGDIAEGLLTSVTGSAGQFCTKPGLVFVPSGADGDAFTATLAKLFANAPVAVALNQGIAESYATARAGQSNAANLVAESTGTTSGFAMVPRLFSVDAADLTETVVEECFGPTTVLVRYDTLEALREAVVAKLPSSLTATIHSGTDDEERVAALSTLLRDTTGRVLYNGFPTGVRVSWAQNHGGPWPSTNSAHTSVGATAIRRFLRPVTWQNAPAFVLPPELRDEATDVPRRIDGELRLPGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q157</accession>
    <name>D3Q157_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021208.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6011"/>
    <dbReference type="EnsemblBacteria" id="ADD45637">
        <property type="protein sequence ID" value="ADD45637"/>
        <property type="gene ID" value="Snas_6011"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6011"/>
    <dbReference type="eggNOG" id="ENOG502ZSFE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095649_0_1_11"/>
    <dbReference type="OMA" id="CETHSER"/>
    <dbReference type="OrthoDB" id="2033994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021888">
        <property type="entry name" value="DUF3499"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12005">
        <property type="entry name" value="DUF3499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="133" mass="14588" checksum="96F58F42D1487541" modified="2010-04-20" version="1">MRSHRRCSRNGCRESAVATLTYVYVDSTAVVGPLATTQEPHTYDLCEDHARKLTAPRGWDLVRHVDDYAAPMPSGDDLVALADAVRESARTRARPPENPTPPRRPTEPSRGRPHLRVVGGGADTDGTQPPQRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q188</accession>
    <name>D3Q188_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Amidinotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021239.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6044"/>
    <dbReference type="EnsemblBacteria" id="ADD45668">
        <property type="protein sequence ID" value="ADD45668"/>
        <property type="gene ID" value="Snas_6044"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6044"/>
    <dbReference type="eggNOG" id="COG1834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057463_0_0_11"/>
    <dbReference type="OMA" id="KCCIAEL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="271" mass="29642" checksum="C4C2527B683A8AC0" modified="2010-04-20" version="1">MTAETARERQYLLATPTHFTVAYAINPWMDATEPVDTARAIEQWQGLVTALTDRGHRVHVLDPEPGLPDMVYAANGAFSVGGVVFGAKFRYPQRAAEAAAHEKWYRERGWRFVAPAEVNEGEGDFAYVPGPGLALAGYGFRTEPRAHAEAAEALKRPVISLKLVDERFYHLDTALTVLDDDTIAYYPQAFSAASQEILRRLFPTAVIADEADALAFGLNLVSDDKHVFINAEATGMADKLAARGYEPVVVDLSELKKGGGSVKCCIAELRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1G8</accession>
    <name>D3Q1G8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021319.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6124"/>
    <dbReference type="EnsemblBacteria" id="ADD45748">
        <property type="protein sequence ID" value="ADD45748"/>
        <property type="gene ID" value="Snas_6124"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6124"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="MAFGRWI"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="36147" checksum="AB0332E276B9CED8" modified="2010-04-20" version="1">MEYIRLGDHGLRVSRICLGMMSYGDPNLDAWVLPQADAEPIVRAAVEAGITFFDTADMYSDGASEEITGRLLSKLFRRREDYVLATKVYFPMGKGPNDSGLSRKHILDGVDASLRRLGTDHVDLYQIHRWDYDTPIAETMEALHDVVRSGKARYIGASSMYAWQFAKAQHIAAANGWTPFVSMQNHYNLVYREEEREMIPQCRDQGVGVLPWSPLARGLLAGTRERGGGRNTLRSGTDPLLDERYSDNDFDIVDVLREVAAERGEAPAKVALAWLLSRPGVTAPIVGATKPGHLADAVAAVSLRLTDAEIARLEEPYRPRPISGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1K2</accession>
    <name>D3Q1K2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsR</name>
        <name evidence="6" type="ordered locus">Snas_0129</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015421.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0129"/>
    <dbReference type="EnsemblBacteria" id="ADD39850">
        <property type="protein sequence ID" value="ADD39850"/>
        <property type="gene ID" value="Snas_0129"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0129"/>
    <dbReference type="eggNOG" id="COG0238">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148710_1_0_11"/>
    <dbReference type="OMA" id="QKKYCRF"/>
    <dbReference type="OrthoDB" id="1940575at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_S18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018275">
        <property type="entry name" value="Ribosomal_S18_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_S18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="PTHR13479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="SSF46911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00057">
        <property type="entry name" value="RIBOSOMAL_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="79" mass="8969" checksum="68B743CD489EA5E8" modified="2010-04-20" version="1">MAKAAPVRKPKKKSNPLDKEGITYIDFKDTALLRKFISDRGKIRARRVTGVTAQQQRQIARAVKNAREMALLPYTSQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1X1</accession>
    <name>D3Q1X1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017409.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2144"/>
    <dbReference type="EnsemblBacteria" id="ADD41838">
        <property type="protein sequence ID" value="ADD41838"/>
        <property type="gene ID" value="Snas_2144"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2144"/>
    <dbReference type="eggNOG" id="COG4668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072531_3_0_11"/>
    <dbReference type="OMA" id="EDYIQAM"/>
    <dbReference type="OrthoDB" id="1810962at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00372">
        <property type="entry name" value="PTS_EIIA_TYPE_2_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="1">
        <location>
            <begin position="3"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="148" mass="15680" checksum="C22F28D139A6DA7D" modified="2010-04-20" version="1">MSELLTENAVRLTETAADRDTAIRRCGEVLVEIGAATPDYVDAMLEREKSISTYVGEGVAIPHGTVASKSAITRDALAVLRFPDGVDWGGSEVRVCVAIAARGEGHVELLSALAEVLMDPDSAERLREATDAQTVLNLLESIGKDSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q226</accession>
    <name>D3Q226_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidate cytidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2202</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017464.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2202"/>
    <dbReference type="EnsemblBacteria" id="ADD41893">
        <property type="protein sequence ID" value="ADD41893"/>
        <property type="gene ID" value="Snas_2202"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2202"/>
    <dbReference type="eggNOG" id="COG0575">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037294_0_0_11"/>
    <dbReference type="OMA" id="FGKHPMA"/>
    <dbReference type="OrthoDB" id="1533756at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="339" mass="34969" checksum="93D599BE5DB588B1" modified="2010-04-20" version="1">MGRHNTPPTGMPRPGPGGHHQPARPQPGPGPGFPPGPPPPPPGYGDHDNPVADPQQPSEAWQDASKPPSRAGRNLPLAVAAGVILGAVVLGSLLIYRQIFLAVIAIAIGVAIWELSQAMRTAGIRVPTWTLLACGLGMQGLTWFGGPEMLALGLGVTVVVLVVWRFADGATGYHSDIPAATLVGVFVPFLGGFAVLLLAPPDGAKRVIATLLVVVLSDTGGYIAGVLAGRHPMAPTISPKKSWEGMGGSLVACAIGGAVTLQLMFDVPWWQGAVFGVALAITATVGDLTESLIKRDLGVKDMSRLVPGHGGLMDRLDSILLALPVAYALLTYLAPVGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q280</accession>
    <name>D3Q280_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4162</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4162"/>
    <dbReference type="EnsemblBacteria" id="ADD43813">
        <property type="protein sequence ID" value="ADD43813"/>
        <property type="gene ID" value="Snas_4162"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4162"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024630_1_0_11"/>
    <dbReference type="OMA" id="DELWHRF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007139">
        <property type="entry name" value="DUF349"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03993">
        <property type="entry name" value="DUF349"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="117"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="425" mass="46831" checksum="D402A5F3F2EEC752" modified="2010-04-20" version="1">MTIGRATAPEIPAKEKVNTMSGENPDATQFGRIDPGGTVYLKTSAGERVIGSWQAGSPEEGLAHFARRYDDLVTEVDLVAARLNSGNADPASTASAIKKLRVSLDEAHVIGDVDKLAARLDELASRSEAKVAEAKEAKSAARAEAVARKEALATEAEKLAADSTQWKAAGDRIKAIAEEWKTIHGADRKSDQALWKRFAAARDGFTRRRGAHFASLDSERKVIATAKEELIAEAEKLATSTDWAETADQLKGLMRQWKEAGRVAPDAEQKLWKRFRAAQDTFFSARSEAFSARDAEFKENLNQKRELLTQAEAIDVEADPRAAQAKLREIQGQWEEIGRVPKESAGGLQRRLRAVDDKIRAALDVAWRRTPVSENPLLAQMREQVDKAERQLERAKNDGDAKRIAAAEEALNSKRQFLELAEKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2D2</accession>
    <name>D3Q2D2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_4216</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4216"/>
    <dbReference type="REBASE" id="24811">
        <property type="entry name" value="M.SnaDORF4216P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43865">
        <property type="protein sequence ID" value="ADD43865"/>
        <property type="gene ID" value="Snas_4216"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4216"/>
    <dbReference type="eggNOG" id="COG0270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006958_5_3_11"/>
    <dbReference type="OMA" id="AIARWEH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="184"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="207"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="329" mass="35801" checksum="2DE39477D066064C" modified="2010-04-20" version="1">MSLQQDTLRTRPQWRVFSRRVGGELVPRIGSLCSGIGALDDAVAAVTGAELAWVADTDPDAARVLTHRHPHAPNLGDIRTAPWEDAEPVDILVAGVPCQPVSKAGKRTGVADARWLWPHAARAVRDLRPALIVLENVAALRTRGLGDILTDLAALGYDARWLCLRACELGAPHQRDRMFLAAATHPQRHPRSQDHPNRFAAAGSGRTPSHPASQRRHQRLTPPTGLQRGRDLAVTGAETWGKYAPAIARWEHLTARPAPAPTAPTGRGEARRLSPRFVEWMMGINSGHVTDVEGISRTAQLRLLGNSVVPAQAEAAVRLLLDDTLWPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2F3</accession>
    <name>D3Q2F3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019457.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4237"/>
    <dbReference type="EnsemblBacteria" id="ADD43886">
        <property type="protein sequence ID" value="ADD43886"/>
        <property type="gene ID" value="Snas_4237"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4237"/>
    <dbReference type="eggNOG" id="ENOG5033MU7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_344415_0_0_11"/>
    <dbReference type="OMA" id="NEYTIRW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="770" mass="81520" checksum="9A5C1C8CFE7CFE81" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Q3</accession>
    <name>D3Q2Q3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021375.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6181"/>
    <dbReference type="EnsemblBacteria" id="ADD45804">
        <property type="protein sequence ID" value="ADD45804"/>
        <property type="gene ID" value="Snas_6181"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6181"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_31_0_11"/>
    <dbReference type="OMA" id="RFIGYWL"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="155" mass="17165" checksum="5F139BCE15338A51" modified="2010-04-20" version="1">MSEVRLRDCVAADLETFYANETDADAARRVNFPPRTREAFLAHWNDRILADPGVVKRTVVVDARVAGNIVCWDAEGEREVGYWFGREFWGRGIGTAAVRAFVDGVPWRPLYAKAAAANIASVRLLEKCGFAFDSAFAAPNAYGDGEVEHVKTRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2T7</accession>
    <name>D3Q2T7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">7,8-dihydroneopterin aldolase</fullName>
            <ecNumber evidence="1">4.1.2.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6217</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde</text>
            <dbReference type="Rhea" id="RHEA:10540"/>
            <dbReference type="ChEBI" id="CHEBI:17001"/>
            <dbReference type="ChEBI" id="CHEBI:17071"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="EC" id="4.1.2.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHNA family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.25" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021409.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6217"/>
    <dbReference type="EnsemblBacteria" id="ADD45838">
        <property type="protein sequence ID" value="ADD45838"/>
        <property type="gene ID" value="Snas_6217"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6217"/>
    <dbReference type="eggNOG" id="COG1539">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112632_1_1_11"/>
    <dbReference type="OMA" id="GHYKSVA"/>
    <dbReference type="OrthoDB" id="1858654at2"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00154"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004150">
        <property type="term" value="F:dihydroneopterin aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00534">
        <property type="entry name" value="DHNA_DHNTPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006156">
        <property type="entry name" value="Dihydroneopterin_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42844">
        <property type="entry name" value="PTHR42844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00525">
        <property type="entry name" value="folB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00526">
        <property type="entry name" value="folB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FolB" evidence="2">
        <location>
            <begin position="8"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="123" mass="13491" checksum="42235DA1B47024D7" modified="2010-04-20" version="1">MADHTDQITLSGLRVHGYHGVYDRERADGQEFIIDVTLDLDTRKAALSDNIQDTVHYGNLADALVTEVAGAPVRLLETLADRLAGVCLADPRVISCVVTVHKPFAPIPHNFTDVSVTIERSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q325</accession>
    <name>D3Q325_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0277</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015566.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD39995">
        <property type="protein sequence ID" value="ADD39995"/>
        <property type="gene ID" value="Snas_0277"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0277"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_3_2_11"/>
    <dbReference type="OMA" id="SIHFVIA"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="208" mass="21700" checksum="0A9A3CED789B2CDC" modified="2010-04-20" version="1">MLPDAATYLSYLAAIALLTITPGPDMMFVIANAGRWGTRAGIVAALGITVGEALHMTVAALGLASVFAANPVLYQVIRYAGAAYLLYLGVQVLRHRSRASEESAADHSSPRAAFTRGMVTNVLNPKMALFSLAFLPQFIDPAQGAVTGQLLVLGATFVLLQFIVDVGLSVAAGQLGDRFLRRPAVARGVNTVTGAVFIGLGVRLAAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q328</accession>
    <name>D3Q328_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0280</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015569.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0280"/>
    <dbReference type="EnsemblBacteria" id="ADD39998">
        <property type="protein sequence ID" value="ADD39998"/>
        <property type="gene ID" value="Snas_0280"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0280"/>
    <dbReference type="eggNOG" id="COG2807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038046_4_0_11"/>
    <dbReference type="OMA" id="GGYTSMV"/>
    <dbReference type="OrthoDB" id="806182at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049673" evidence="6">
        <location>
            <begin position="37"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="16"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD39998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="400" mass="40088" checksum="A92FD019C4E78CA2" modified="2010-04-20" version="1">MSRVHDRPLAPPGPALLGFAALAMFVAALNLRPALAAVSPLVDAIRSDLGLSATGVALLTTIPTLAMGLFAPFAASVARRFGPRHGVALGLAVIAVGTAARGLGGAAWLQLSCAAAVGAGIAIAQTLLPAIVKARFAARPGLATGVYTAGLGLGGAIAAGVSAPLAATIGSWHGALASWSVLAVVGIAVWLTARPALGPDPATTTAGPATRGLPWRDRTAWRVTVLAAANSALYYCELAWVAALLHDDADRTAVDAGVLLTVLIAIQVVAMLAVPAILGEARDIRFGLTLTTAATALGFAGLALAPATLTWLWIVVLGIGHGGLFTLVLTVPVVISRDAAEAGRISAMAFFVGYACAALAPMLVGGLRDALGDFQLAFALLSGLAVATLLPISKLRPTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q353</accession>
    <name>D3Q353_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015594.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40023">
        <property type="protein sequence ID" value="ADD40023"/>
        <property type="gene ID" value="Snas_0305"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0305"/>
    <dbReference type="eggNOG" id="ENOG502ZQGS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1980204_0_0_11"/>
    <dbReference type="OrthoDB" id="1647498at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="126" mass="13866" checksum="7F0241D7786A2F0B" modified="2010-04-20" version="1">MSSFTASQSRLLGSIVERVVRATGGQSSTVDGLRVCRSGRLRLYGKGGTQYGDVFVTGRSRGPLSDGLIAHEKHHRDAQWRRYGLVFGVMYLAAHVADVWIGRKPLNRYELAAEEASDWGGGYPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q371</accession>
    <name>D3Q371_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0323</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015612.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0323"/>
    <dbReference type="EnsemblBacteria" id="ADD40041">
        <property type="protein sequence ID" value="ADD40041"/>
        <property type="gene ID" value="Snas_0323"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0323"/>
    <dbReference type="HOGENOM" id="CLU_2384729_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="94" mass="10961" checksum="29F11AA1B65C2553" modified="2010-04-20" version="1">MERETHQTWLVWGDTEIEAFLDGYWLTPVGVDDPDLLSMIRDRDPEWEPPNDDVENLDDLNNSCALVVSTITEKEIVERTAEVRKSLRGYIRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3N7</accession>
    <name>D3Q3N7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione transferase</fullName>
            <ecNumber evidence="3">2.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019525.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4307"/>
    <dbReference type="EnsemblBacteria" id="ADD43954">
        <property type="protein sequence ID" value="ADD43954"/>
        <property type="gene ID" value="Snas_4307"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4307"/>
    <dbReference type="eggNOG" id="COG0435">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037263_1_3_11"/>
    <dbReference type="OMA" id="PWANRAI"/>
    <dbReference type="OrthoDB" id="780709at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016639">
        <property type="entry name" value="GST_Omega/GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419">
        <property type="entry name" value="PTHR32419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015753">
        <property type="entry name" value="GST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01206">
        <property type="entry name" value="Xi.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="156"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="313" mass="35461" checksum="78AE98D9E27E62B0" modified="2010-04-20" version="1">MVENNHAVDESGEFQRSRSHFADRITADGSSGWPVEPGRYRLIVSRACPWAHRMLIVRKLLGLEDVISLGVADPIQDELSWRFTLDPGDIDPVLKIAYLGDAYRAREPEYDGGVSVPAIVDIPSGKLVTNDYLQMTLDLSTQWTAYHREGAPDLYPEGMRDEIDAVIEPIFKEFNNGVYRAGFATSQEKYEAAYRDVFGRLDALEERLSTRRFLMGDAITEADIRLFTTLVRFDAVYHGHFKCNRNKLTEMPVLWAYARDLYQTPGFGETVDFDHIKRHYYVVHSDINPTGIVPVGPDASGWSTPHGRESLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Y6</accession>
    <name>D3Q3Y6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4407"/>
    <dbReference type="EnsemblBacteria" id="ADD44053">
        <property type="protein sequence ID" value="ADD44053"/>
        <property type="gene ID" value="Snas_4407"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4407"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_4_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="9"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="230" mass="25549" checksum="F035F237494324D0" modified="2010-04-20" version="1">MPFHAGESLVLRPWFESDVEAVLAAFVTPDMDQQWRQPVRTLTVAREWLAWAVALHNRESGYGFAVCGTDDVPVGNIAVTNINHHDCGWISYWTSARVRGRGIAPDALRGLLPWLHDELRLHRLELGYRSNNPGSGRVAHKAGFLPEGRQRDKLCYDGKRYDVERCARLSNDPRPQPSRPVTVKLDWLLGLVVGVDDRGAQRHPHAEAAEQQPGGLVGAFLDQPGDGLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4I2</accession>
    <name>D3Q4I2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase S1 and S6 chymotrypsin/Hap</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0425</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0425"/>
    <dbReference type="EnsemblBacteria" id="ADD40142">
        <property type="protein sequence ID" value="ADD40142"/>
        <property type="gene ID" value="Snas_0425"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0425"/>
    <dbReference type="eggNOG" id="COG5640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006842_7_5_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049538" evidence="3">
        <location>
            <begin position="32"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="43"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="257" mass="27456" checksum="BEC152EC043D1F68" modified="2010-04-20" version="1">MFRSKLRKLLPIAVFVALAIPAAFVTLPALADDTGKSSDDSRIVGGGTVPASTKTPWIVALHNNGDFRCTSTQISRNWILTAAHCVTTGGKYKARIGAKTRSSGGKVIDISTIKIHPKYQQGNLYDIAVIKLKTPHTNTYPKLAFSKSHLKLGQASTIYGWGATKADWTGPLPEKLKYSKGKTTKKYCEMPEDVCVIGDGAVAGGDSGGPVFIKSASTGKTMLAGACEAGHNPANWKWGGYASTVFHQKWIKGTTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q521</accession>
    <name>D3Q521_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4425</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019641.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4425"/>
    <dbReference type="EnsemblBacteria" id="ADD44070">
        <property type="protein sequence ID" value="ADD44070"/>
        <property type="gene ID" value="Snas_4425"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4425"/>
    <dbReference type="eggNOG" id="COG1187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024979_1_2_11"/>
    <dbReference type="OMA" id="HVPKTYE"/>
    <dbReference type="OrthoDB" id="1037615at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="8"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="244" mass="26701" checksum="C4273A6B207FC018" modified="2010-04-20" version="1">MTAEPEGVRLQKVMAAAGIGSRRACENLIAAGRVTVNGKKAQLGNRVDPQHAVIHVDGERVITDTKLVHFALNKPRGYVSTMDDELKRPDLNEFTAGISERVFHVGRLDTESEGLLLLTNDGELGNRLTHPSYEIAKTYRCQVTGYAGPAIARRLAAGVVLEDGPVTVDDFKVIDEHADQALVEIVVHEGRKHVVRRLLAEVGLPVNRLVRTAIGDIRLANLKPGTLRKLRPDEIASLYRTVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5B3</accession>
    <name>D3Q5B3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isochorismatase</fullName>
            <ecNumber evidence="3">3.3.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4517</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + isochorismate = (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:11112"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="ChEBI" id="CHEBI:58764"/>
            <dbReference type="EC" id="3.3.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
        <text evidence="4">Binds 1 phosphopantetheine covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="3.3.2.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019733.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4517"/>
    <dbReference type="EnsemblBacteria" id="ADD44162">
        <property type="protein sequence ID" value="ADD44162"/>
        <property type="gene ID" value="Snas_4517"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4517"/>
    <dbReference type="eggNOG" id="COG1535">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3433">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068979_2_0_11"/>
    <dbReference type="OMA" id="RDIKPFF"/>
    <dbReference type="OrthoDB" id="1442962at2"/>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008908">
        <property type="term" value="F:isochorismatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016291">
        <property type="entry name" value="Isochorismatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001111">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01398">
        <property type="entry name" value="ISCHRISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="6">
        <location>
            <begin position="32"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="207"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001111-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="270" mass="29677" checksum="788B1B140BDFF8BB" modified="2010-04-20" version="1">MSIPTLDIYPLPTEAELPKPRVPWTFDPNRAALLIHDMQRYFLDFYGEEFGELVDNIAQLRKLDLPTFYTAQPPKQSPDERGLLSDRWGPGIQDREDIVAPLAPASSDVVLTKHRYSAFHRTDLAERLAAAGRDQLIITGVYAHIGITATALDAFSHGIETFVIADAIADFGRGRHVAALEHLSATCAVVTTLNRLLDSGFGLADVRAQVLALLDEPADDDENLIDAGLDSIRVMGLIEDWKERGHNVTFADLAADPTIRGFHAALEAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5G2</accession>
    <name>D3Q5G2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoribosylformylglycinamidine synthase subunit PurQ</fullName>
            <shortName evidence="1">FGAM synthase</shortName>
            <ecNumber evidence="1">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Formylglycinamide ribonucleotide amidotransferase subunit I</fullName>
            <shortName evidence="1">FGAR amidotransferase I</shortName>
            <shortName evidence="1">FGAR-AT I</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Glutaminase PurQ</fullName>
            <ecNumber evidence="1">3.5.1.2</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Phosphoribosylformylglycinamidine synthase subunit I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">purQ</name>
        <name evidence="2" type="ordered locus">Snas_6406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="1"/>
    <dbReference type="EC" id="3.5.1.2" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021593.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6406"/>
    <dbReference type="EnsemblBacteria" id="ADD46022">
        <property type="protein sequence ID" value="ADD46022"/>
        <property type="gene ID" value="Snas_6406"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6406"/>
    <dbReference type="eggNOG" id="COG0047">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001031_3_1_11"/>
    <dbReference type="OMA" id="LHFVCRD"/>
    <dbReference type="OrthoDB" id="1527083at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00421">
        <property type="entry name" value="PurQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010075">
        <property type="entry name" value="PRibForGlyAmidine_synth_PurQ"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001586">
        <property type="entry name" value="FGAM_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01737">
        <property type="entry name" value="FGAM_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD46022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="226" mass="23881" checksum="82A038DF64E0E4FD" modified="2010-04-20" version="1">MSARIGVVTFPGSLDDVDTHRAIARAGGTPVPLWHDDSALRGVAAIVLPGGFSYGDYLRCGAIARFSAVMETIVEVAAEGMPILGICNGFQVLCESHLLPGALVRNKHRRYRIGHQPLAMSNDSAWTSGYESGQRAVIPVKHGEGCYVADEATLDELESSGRVVARYLDGNPNGSMRDIAGIRNAAGNVVGMMPHPEHAIDPLTGSSSDGLTIFSSVLKQLGVGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5G8</accession>
    <name>D3Q5G8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6412</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021599.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6412"/>
    <dbReference type="EnsemblBacteria" id="ADD46028">
        <property type="protein sequence ID" value="ADD46028"/>
        <property type="gene ID" value="Snas_6412"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6412"/>
    <dbReference type="eggNOG" id="COG4223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_459130_0_0_11"/>
    <dbReference type="OMA" id="TLPQDYW"/>
    <dbReference type="OrthoDB" id="410703at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="498"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="584"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD46028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="725" mass="77407" checksum="652EAB271CBE6F69" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5P2</accession>
    <name>D3Q5P2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmH</name>
        <name evidence="6" type="ordered locus">Snas_6487</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021673.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6487"/>
    <dbReference type="EnsemblBacteria" id="ADD46102">
        <property type="protein sequence ID" value="ADD46102"/>
        <property type="gene ID" value="Snas_6487"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6487"/>
    <dbReference type="eggNOG" id="COG0230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129938_2_1_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_L34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020939">
        <property type="entry name" value="Ribosomal_L34_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00784">
        <property type="entry name" value="RIBOSOMAL_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD46102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="45" mass="5307" checksum="FB0A8E22977E6EFA" modified="2010-04-20" version="1">MSKRTFQPNNRRRAKTHGFRLRMRTRAGRAIVAARRRQGRAKLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5T7</accession>
    <name>D3Q5T7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transmembrane anti-sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015807.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0521"/>
    <dbReference type="EnsemblBacteria" id="ADD40236">
        <property type="protein sequence ID" value="ADD40236"/>
        <property type="gene ID" value="Snas_0521"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0521"/>
    <dbReference type="eggNOG" id="COG5662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056526_1_0_11"/>
    <dbReference type="OMA" id="ELNWACE"/>
    <dbReference type="OrthoDB" id="1740922at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="zf-HC2" evidence="2">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="223" mass="24215" checksum="9DE44E5802495142" modified="2010-04-20" version="1">MSDCAFPHDAAAYVLGALEPAERERFEAHLPECESCAATVREFTELPGVLAHAPVEELSAEPAPETLLPTLVRKVRKDRRRRLFRAVVVTAAAVALFAVGALTAVNLFTSEATAPSLDVALQPIAAVQITSEAGMIPQNEGTRIELSCDEKNTDDNPDSGYGGKYAYRLVVTNTKGETDVAGSWTGADDGSTRVVLFTRWKPQDIASLEIQTMDKKPIMRWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5V6</accession>
    <name>D3Q5V6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0541</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015826.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0541"/>
    <dbReference type="EnsemblBacteria" id="ADD40255">
        <property type="protein sequence ID" value="ADD40255"/>
        <property type="gene ID" value="Snas_0541"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0541"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="IIAYDTG"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="150"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="23788" checksum="6DEF0A7B91DE74C7" modified="2010-04-20" version="1">MDEPLRLLVVDDQTLVREALAGLLDAEPEFTVVGQAADGSEVPALARDSDPDIVIMDVRMPDVDGVEATARLTRERPQSKVILLTTFDVDAYVYAGLRAGASGFLLKDSHAATLIAAVHTVASGNAVLSPWATSRLVSTFAPLLPEPLATPPRLKALTARERDVLSLTGRGLSNNEIATELGIGYETVKSHLRSVMTKLRLRDRVHAVIVAYETGLLRPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6C8</accession>
    <name>D3Q6C8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2625</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017874.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2625"/>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42303">
        <property type="protein sequence ID" value="ADD42303"/>
        <property type="gene ID" value="Snas_2625"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2625"/>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_4_0_11"/>
    <dbReference type="OMA" id="GWLCTFY"/>
    <dbReference type="OrthoDB" id="949956at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fn3_like" evidence="4">
        <location>
            <begin position="739"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="820" mass="87965" checksum="D3A6896BEEA4C0B4" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6E2</accession>
    <name>D3Q6E2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019756.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4540"/>
    <dbReference type="EnsemblBacteria" id="ADD44185">
        <property type="protein sequence ID" value="ADD44185"/>
        <property type="gene ID" value="Snas_4540"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4540"/>
    <dbReference type="eggNOG" id="ENOG5031SRY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120892_2_0_11"/>
    <dbReference type="OrthoDB" id="1978329at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021449">
        <property type="entry name" value="DUF3099"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11298">
        <property type="entry name" value="DUF3099"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="121" mass="13410" checksum="8F3F4EBDFD309534" modified="2010-04-20" version="1">MAQSHAKPALITDAEQSRHEQLRSRQIRYGVMMGIRALLLIIATVLVMAEVPLLWLWLSACAVGMVVLPWSAVLIANDRPAKKQHRMRRFGASKAEEPEARRLDSAEAKVIDIDSPGDATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6E9</accession>
    <name>D3Q6E9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4547"/>
    <dbReference type="EnsemblBacteria" id="ADD44192">
        <property type="protein sequence ID" value="ADD44192"/>
        <property type="gene ID" value="Snas_4547"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4547"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_11"/>
    <dbReference type="OMA" id="FASQCTE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="20"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="278" mass="30667" checksum="40844DECA727AD4D" modified="2010-04-20" version="1">MRMNQFSETIHIGGDLPVHRLGFGAMRLTPDRWPTPAEKEHGIAVARRALELGVTLIDTADSYSYGANEELLAEALHPYPDNLVIATKAGQSRPDGAWRPLGRPEYLKQQAELSLRRLRLDRIDLFQLHRIDPQVPFDDQIGALKEMRDSGMIRHIGLSEVGVAEIERARRIVDIVSVQNLYNVADRRHEAVVDYCEKNGIAFIPWLPVANGSHASSTSPVAALARELGATPIQAALAWQLHRSPVIVPIPGTKSAEHLAENMAAANLRLTEAQLAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6N5</accession>
    <name>D3Q6N5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019849.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4635"/>
    <dbReference type="EnsemblBacteria" id="ADD44278">
        <property type="protein sequence ID" value="ADD44278"/>
        <property type="gene ID" value="Snas_4635"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4635"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_14_1_11"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="437" mass="45668" checksum="F3C5361BCE7039E1" modified="2010-04-20" version="1">MTNDSRSEAAGERPATYREVFASAELTALFASFAVSKAGSMLARVAVTFLVYNNTNSPLLATGTFAITYAPYLGPAQLLAALADRMSYRTTMVVSDFLRMIFIGLVGVIAVLPIETAVALPFMLVLVFAAAMVEPAYQSARSAMMPRLVEGDALTLALSVYLTLNQSAQLAGYFLGGVIAAINPDIALFINAGAFALSGVVLLIFVKKRPPVTNGEPRENIFAETAAGFKLVFGNRILRIIALVVFTTIMFTIIPEGAAAPWAHEVGGTAVLQGVIMASAPIAAIVSSVVFTRFTPPNLRRKLIRPLVFLAPLALVPALFEPSGTMVVVIAVVCNLTMASLSPLNAIFVKAVPDGYRARAFSVMQSGMMLIQGIAVVSIGALTKLGLSVAHTVGAWGVAGTIVVGGLLVFWPASSEFDDAVAAASPPAEPAKQAGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6W2</accession>
    <name>D3Q6W2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015932.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0648"/>
    <dbReference type="EnsemblBacteria" id="ADD40361">
        <property type="protein sequence ID" value="ADD40361"/>
        <property type="gene ID" value="Snas_0648"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0648"/>
    <dbReference type="eggNOG" id="COG0584">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1010157_0_0_11"/>
    <dbReference type="OrthoDB" id="1458249at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049600" evidence="1">
        <location>
            <begin position="32"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="279" mass="31300" checksum="07E36DA49413EA55" modified="2010-04-20" version="1">MRTRRTRWLLSAVTILAGVGAMTAMTLPAQAEDRNLPKCPQVFTHGGYPEVNPDGWKRDQVRQPNNPMALQAYKDMGSVGVEADIQLTKDGHKAVMWHNGSTYWLTGSHRNVNDIWWNTGPDKMSGRTIEVGPFKGETVYTLRGYLDSLYEKKMVPLLEIKPSAAQSLLHSDAGVRDGAWKEVIDPIRERIDRQEIMIYTHDANLRPEMQARFKAAGLEKAFPTAETGPVWPDTVGWEEPPPAADGNFASWQAALDKGPNRMATDWPKEMVAWLKGKCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q739</accession>
    <name>D3Q739_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">greA</name>
        <name evidence="7" type="ordered locus">Snas_0726</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GreA/GreB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0726"/>
    <dbReference type="EnsemblBacteria" id="ADD40438">
        <property type="protein sequence ID" value="ADD40438"/>
        <property type="gene ID" value="Snas_0726"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0726"/>
    <dbReference type="eggNOG" id="COG0782">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101379_0_0_11"/>
    <dbReference type="OMA" id="TWLTQEA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="6">
        <location>
            <begin position="12"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="5">
        <location>
            <begin position="90"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="167" mass="18074" checksum="6A1CC049141AB1E7" modified="2010-04-20" version="1">MSMTDNSSTGAWLSQEAYDRLKAELDEHIANRPAMAAEINARREEGDLRENGGYHAAKDEQGKIESRIRYLEDFLRKAQVGEAPVDVKGVTPGSVVTIAFDDDPEDTETFLLGSREISATTDLTVYSPESALGAAILGHAEGDTVTYTAPSGAELKVKVLKLEPFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Q3</accession>
    <name>D3Q7Q3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemolysin-type calcium-binding region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4753"/>
    <dbReference type="EnsemblBacteria" id="ADD44395">
        <property type="protein sequence ID" value="ADD44395"/>
        <property type="gene ID" value="Snas_4753"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4753"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_457723_0_0_11"/>
    <dbReference type="OrthoDB" id="1560944at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028208">
        <property type="entry name" value="Effector_pro_NleD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14891">
        <property type="entry name" value="Peptidase_M91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="705"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="724" mass="76379" checksum="32EFFD4B07ACD27D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7S2</accession>
    <name>D3Q7S2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019985.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44414">
        <property type="protein sequence ID" value="ADD44414"/>
        <property type="gene ID" value="Snas_4772"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4772"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_11_8_11"/>
    <dbReference type="OrthoDB" id="1983082at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="166" mass="17813" checksum="2B7B6DB479749360" modified="2010-04-20" version="1">MTTTVSIRIIDVKLDTPTARELIGELNVELARQYPEEGANHFRLDPDEVAPGKGAFLVAEDTESGRALGCGAIRVLTPDTAELKRMYVRPVARGRGVGSTLLRALEERAVALGVERLVLETGTRQVPALGLYYGAGYAEIERFGEYADSPLSMCLAKPLVPAGVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q811</accession>
    <name>D3Q811_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0804</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0804"/>
    <dbReference type="EnsemblBacteria" id="ADD40516">
        <property type="protein sequence ID" value="ADD40516"/>
        <property type="gene ID" value="Snas_0804"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0804"/>
    <dbReference type="HOGENOM" id="CLU_1814640_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="142" mass="15435" checksum="BAEAD981CF283B9B" modified="2010-04-20" version="1">MKTDRWFHCSRTVAASGDALTLLRERLDCLYAAGDADGYSLVVVALAPEAGGFDRLAMRLSYARILSEATGVPAAMTGAALAVALINRDRNLSATLAMLRMRLGRATTTGRPPRVWLERLPAELPMAYELLDELSELSTSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8B3</accession>
    <name>D3Q8B3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein-tyrosine phosphatase, low molecular weight</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018058.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2811"/>
    <dbReference type="EnsemblBacteria" id="ADD42487">
        <property type="protein sequence ID" value="ADD42487"/>
        <property type="gene ID" value="Snas_2811"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2811"/>
    <dbReference type="eggNOG" id="COG0394">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071415_3_3_11"/>
    <dbReference type="OMA" id="VISLCGC"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="1">
        <location>
            <begin position="5"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="136" mass="14716" checksum="9FD48774BEC8FC28" modified="2010-04-20" version="1">MTTKPEVLFVCVHNAGRSQMAAAIMDYLADGRVSVRSAGSAPAEQINPAVVEAMAELGLDLSKEVPKKLLDETVKASDVVITMGCGDACPVYPGKRYLNWELDDPAGQPVEKVRAVRDEIHARVRRLLAELETPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8C8</accession>
    <name>D3Q8C8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2826"/>
    <dbReference type="EnsemblBacteria" id="ADD42502">
        <property type="protein sequence ID" value="ADD42502"/>
        <property type="gene ID" value="Snas_2826"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2826"/>
    <dbReference type="eggNOG" id="COG0657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_6_4_11"/>
    <dbReference type="OMA" id="RRFVYGN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="1">
        <location>
            <begin position="93"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="323" mass="34767" checksum="91CEEC924F82761F" modified="2010-04-20" version="1">MSETVATRRPPLGVRLAYGLRKEPDWPRLSAAELAAVQQAHNRRMESGLIRLITGFPERGVRIDWERVTLPDRRVRVRVYRPSDDRDSRLPLVVHVHGGGFVGTAAQCDWNNSRMAALPAVVVSVEHRLLSPGIALSAAVDDGWDVLRHLVEHAADWGVDPARVAIVGESTGGAIVALAAMRARQAGLVLRAQVLVNPALDVTASAFDYASMVEFRDSPTLTSSQLELFRRLAAPEGTNAAAVSPLRAEDLGGLAAALVVVPELDPLADQGRAYVARLREAGTPVQLSEHSLAGHAFLSMPGLVSQAKAARDRIAAFLSERFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8M5</accession>
    <name>D3Q8M5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="5">2.1.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ketopantoate hydroxymethyltransferase</fullName>
            <shortName evidence="5">KPHMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">panB</name>
        <name evidence="9" type="ordered locus">Snas_4826</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Homodecamer; pentamer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the PanB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020038.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4826"/>
    <dbReference type="EnsemblBacteria" id="ADD44467">
        <property type="protein sequence ID" value="ADD44467"/>
        <property type="gene ID" value="Snas_4826"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4826"/>
    <dbReference type="eggNOG" id="COG0413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036645_1_0_11"/>
    <dbReference type="OMA" id="VLVWTDM"/>
    <dbReference type="OrthoDB" id="916845at2"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="PTHR20881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Alpha-ketoisovalerate binding" evidence="5 7">
        <location>
            <begin position="61"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7 8">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="280" mass="29850" checksum="0E7788503678AB2D" modified="2010-04-20" version="1">MSEHKEVPSLYGPARKTSRVRTRDLKLAKERGEKWAMLTSYDQYTAAMFDEIGIPALLIGDSAANNVFGYETTLPVTIDELLPLVSAVVRSTKRTLVVADLPFGSYEASPQQALESAVRFMKAGANAVKLEGGVRMREQIAALTGAGIPVMAHIGFTPQSENLVGGYRVAGRGEHADSVLADAYAVAEAGAFAVVLEMVMSDVAARVTKELEIPTIGIGAGGDTDAQVLVWQDMAGLRQGPAPRFVKRYANVASVIAEAAKTYADEVKNGAFPAPEHGFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8U9</accession>
    <name>D3Q8U9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020112.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4900"/>
    <dbReference type="EnsemblBacteria" id="ADD44541">
        <property type="protein sequence ID" value="ADD44541"/>
        <property type="gene ID" value="Snas_4900"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4900"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_11"/>
    <dbReference type="OMA" id="IMITARV"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="127"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="127"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="24105" checksum="72D82A9D8AC0548B" modified="2010-04-20" version="1">MSRILIIEDSERITAFLTKGLAAAGFTPSVAHTGAEGLGRALTGEVDLIVLDIGLPDMDGFDLLRALRAAGRDTPVIILTARDSATDRVTGLSDGADDYMPKPFSVDELLARIRLRLRPVSGGGSDQAVLRVGDLELDLRTRAVRAGGRQVELTARELSLLDTLMRNAGQVLSREQLLSRVWGFDFDPGSNVVDVYVRYLRRKIGADRIETVRGLGYRLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q934</accession>
    <name>D3Q934_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Stearoyl-CoA 9-desaturase</fullName>
            <ecNumber evidence="10">1.14.19.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_0932</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.14.19.1" evidence="10"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016214.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0932"/>
    <dbReference type="EnsemblBacteria" id="ADD40643">
        <property type="protein sequence ID" value="ADD40643"/>
        <property type="gene ID" value="Snas_0932"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0932"/>
    <dbReference type="eggNOG" id="COG1398">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027359_1_1_11"/>
    <dbReference type="OMA" id="FWVTTHR"/>
    <dbReference type="OrthoDB" id="797871at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004768">
        <property type="term" value="F:stearoyl-CoA 9-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="PTHR11351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="9">
        <location>
            <begin position="64"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD40643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="331" mass="37271" checksum="39746DE30198F2F7" modified="2010-04-20" version="1">MTTFTGTESGKTAPVGERTAPEPKPLTVGKQSTGTLMGLWFVVLGPFVALAVAIPLLWGWGVSWIDLAIAVVMYNVSGFGVTVGFHRYFTHGGFRAKRWMRVTLAVAGSLSAEGSVIQWVADHRRHHAFSDKEGDPHSPWRYGTSFGALMKGMWHAHVGWMFKRDMTNPERFTPDLLADKDIRRVDNMFGLLFATTLLAPAIVGGLVTWSWQGALTAFLWGSLVRIGFLHHVTWSINSVCHVWGERPFATRDGDKAANFWPLALLSMGESWHNLHHSDPTCARHGVMRGQIDTSARLIWIFEKFGWVDEVRWPKRQRLEKKMSGKYDRLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q957</accession>
    <name>D3Q957_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="3">1.8.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0956</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0956"/>
    <dbReference type="EnsemblBacteria" id="ADD40666">
        <property type="protein sequence ID" value="ADD40666"/>
        <property type="gene ID" value="Snas_0956"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0956"/>
    <dbReference type="eggNOG" id="COG0225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_524700_0_0_11"/>
    <dbReference type="OMA" id="LMAGFRY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="6">
        <location>
            <begin position="8"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="6">
        <location>
            <begin position="152"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="PMSR" evidence="7">
        <location>
            <begin position="375"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="519" mass="55786" checksum="2EFFAD69197DB566" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9C4</accession>
    <name>D3Q9C4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018177.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2931"/>
    <dbReference type="EnsemblBacteria" id="ADD42606">
        <property type="protein sequence ID" value="ADD42606"/>
        <property type="gene ID" value="Snas_2931"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2931"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_563715_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="484" mass="51530" checksum="DD176AE9B24D4FE5" modified="2010-04-20" version="1">MTDPTSPHTGTQPVVPISPTYPGVAVPTAPRPAGSTAVALIIAGLATVLLVAVGGIILFTTTDGPSGQRGVWNGPIAYPEGMGDGTYHDVVFAGETVYFRTTSQDRKTWITAADAKTGAEKWSLDEGLAVGEEYSVTYIDPGQDALLVQETASSSTNAFLVDAKTGKAHELTSQDSGTYHRMIGGVPVRTTTGGDMEVLDANGDKIWDASIDVGSGDNTVAVASADNLGDLPYAGNPIDAKQLLTVGYDGSVKILDKKDGKVVTEKKSAVTEGSVALLAFDDVLYAKTTNDDRTRETITAYDMKDDFAKIDSWKGEKGQTFTQLSPCTAKLMCASGYWTSEPTRSGNAVIDLKEGVVWKAPEDKEASYASISFVGDTMAVAYFSSYSTDSPIETQLYDKDFKEMGEILQGWYTAADDKVFAAVSASDYTSAEAKVYDAEVSIVEAEDGRVSKLDSYPAYPGCEIAGPNLACATEPGYRLWKYRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9L9</accession>
    <name>D3Q9L9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020136.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4924"/>
    <dbReference type="EnsemblBacteria" id="ADD44565">
        <property type="protein sequence ID" value="ADD44565"/>
        <property type="gene ID" value="Snas_4924"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4924"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087580_2_1_11"/>
    <dbReference type="OMA" id="TGRQRWW"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="193" mass="22275" checksum="06E42BCB91ADCD06" modified="2010-04-20" version="1">MSEVRRITDPETLKALAHPMRQKLQRLLLQLGPATVGTLAEKVDGDPGQVSYHLRKLAEAGFIEEAPELVRDFRQRWWRAVLEPHSWSSSDFESPAGRVLVKTLNAQWVVEQFQAVRESRKSTAKEQFGEEWQGASTSSQSFLRLTAAETIEMVAEFQALCKRWSRYSEEHRDDGTPGRENVRFFYHTFPERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA40</accession>
    <name>D3QA40_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1042</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1042"/>
    <dbReference type="EnsemblBacteria" id="ADD40752">
        <property type="protein sequence ID" value="ADD40752"/>
        <property type="gene ID" value="Snas_1042"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1042"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_3_11"/>
    <dbReference type="OMA" id="AIFRTMD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="72"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="292" mass="32098" checksum="E65E20FF7F9226BF" modified="2010-04-20" version="1">MTTDVKAAERRLGLWLCAPAAAFMLLVAGWPILYSVILSFKRYDLRFPDDQAWVGFSNYATVLTNEFWWTSFGVTMIITVVSVAFELVLGMALAQVMYRTLVAKGLLRTVVLIPYGIVTVVAAFGWFYAWTPGTGWLAAMLPDGEAPLTEFWPAIGIIILAEVWKTTPFMALLLLAGLAIVPEELHRAAAMDGAGRWQRFVRITLPLMRPAIAVALLFRILDAFRIYDNIYVLTKGSQSTGSVSILTYRNLVSGLNLGIGSTMSVLIFITVAIIAFFFVTVLKTGTPGQGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA66</accession>
    <name>D3QA66_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Colicin V production protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1068</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1068"/>
    <dbReference type="MEROPS" id="S01.513"/>
    <dbReference type="EnsemblBacteria" id="ADD40778">
        <property type="protein sequence ID" value="ADD40778"/>
        <property type="gene ID" value="Snas_1068"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1068"/>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1286">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043139_0_0_11"/>
    <dbReference type="OMA" id="YRQGFVV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003825">
        <property type="entry name" value="Colicin-V_CvpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02674">
        <property type="entry name" value="Colicin_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="397" mass="41404" checksum="BF530B87C5321915" modified="2010-04-20" version="1">MQGGILVDIVIVLLALLFAINGYRQGFIIGALGFAGFFGGALIGVQIAPLLVEVSEAPAARVLIALLVVFGIAMLGQWGGSALGVRLRKRVKNDNAKRFDEFGGALVSMVAVLLVAWVVAAPLASSGMPGLAAAVRNSAIVRTIDENMPGPAQNVYNALRSAVNTNGFPEVFSGLDPSDSPPVDPPDPELANSKVVRDAEASVLRVSGDAPQCDRHIEGSSFVYDADRDLVLTNAHVVAGTESVSVAGADGDVEARVVVFDDRRDLAVLYAPGLNAPELDTLDEAAESGADTIVLGYPQGGPYTATASRVREHREVTGPDIYDSGEVTREVYSLRSQVRSGNSGGPLISADGDVYGVIFAAAVDDPDTGYAVTMDEARPIMEEGQTTTESVSTKGCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA93</accession>
    <name>D3QA93_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016376.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1095"/>
    <dbReference type="EnsemblBacteria" id="ADD40805">
        <property type="protein sequence ID" value="ADD40805"/>
        <property type="gene ID" value="Snas_1095"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1095"/>
    <dbReference type="eggNOG" id="COG1289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013315_4_0_11"/>
    <dbReference type="OMA" id="SVMVMRP"/>
    <dbReference type="OrthoDB" id="1338660at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="489"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="267"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="696" mass="73836" checksum="B6DF5613237ED97D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAA4</accession>
    <name>D3QAA4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016387.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1106"/>
    <dbReference type="EnsemblBacteria" id="ADD40816">
        <property type="protein sequence ID" value="ADD40816"/>
        <property type="gene ID" value="Snas_1106"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1106"/>
    <dbReference type="eggNOG" id="ENOG5032DXI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1077367_0_0_11"/>
    <dbReference type="OMA" id="ERPEWAM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="293" mass="31435" checksum="F69C7B7F1BBACC6A" modified="2010-04-20" version="1">MSIIAVQPLLVGAVLLWAANVKLFSRRGAIAARDAALARLVGEKRAPAAYRILGAAEAVVGLALLVPILWAPATVAAIALSAGFCGYLAYARVAAPESSCGCLGGKGAAISWRAFARSGGMLAASVTILWTDMAWPTALAQHPASSLGVVAVEAALFLTVSAEFDGAWLVPLRRWRARWSRPLGGDTGEVPLDATVERMQRSDVFRHVAKLLRSDVRETWDEDDWRIVCYGAMVDGRRATAVFAVPLLRDAPDEVRVAFVDDKTSQTLLHFNSPPEEDERPEWAMPKSATMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAG6</accession>
    <name>D3QAG6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF402 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018320.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3078"/>
    <dbReference type="EnsemblBacteria" id="ADD42749">
        <property type="protein sequence ID" value="ADD42749"/>
        <property type="gene ID" value="Snas_3078"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3078"/>
    <dbReference type="eggNOG" id="COG2306">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083275_1_0_11"/>
    <dbReference type="OMA" id="EDHFLDI"/>
    <dbReference type="OrthoDB" id="1473648at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007295">
        <property type="entry name" value="DUF402"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035930">
        <property type="entry name" value="FomD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04167">
        <property type="entry name" value="DUF402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159234">
        <property type="entry name" value="SSF159234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF402" evidence="1">
        <location>
            <begin position="81"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="220" mass="25209" checksum="342401BCDAB45D76" modified="2010-04-20" version="1">MRFSPGDTIVRRYIHHDGRIGWVVSARVVSDDDRGLLTWVSKDSATAQRFTLTGEATRNLTVDEKFSQPTMHTVAGWRGHGVLMFSPPGAAHSVWWFFEADGGFKGWYVNLEKPGRRWAGGRDCFDQALDVWIYPDRSWNWKDEDEFADYAGRPGYWDEAEAAVIRAEGEAVVKRAEAGQFPFDGTWCDFAPDPSWKPTTLPWWWDQTPDQTGYVRPEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAH8</accession>
    <name>D3QAH8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative signal transduction protein with Nacht domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3090"/>
    <dbReference type="EnsemblBacteria" id="ADD42761">
        <property type="protein sequence ID" value="ADD42761"/>
        <property type="gene ID" value="Snas_3090"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3090"/>
    <dbReference type="eggNOG" id="COG5635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_319797_0_0_11"/>
    <dbReference type="OMA" id="WINTIGR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="NACHT" evidence="3">
        <location>
            <begin position="160"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="808"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="808"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="908" mass="99426" checksum="A7714664C358AC59" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAL8</accession>
    <name>D3QAL8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Periplasmic binding protein/LacI transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018372.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3130"/>
    <dbReference type="EnsemblBacteria" id="ADD42801">
        <property type="protein sequence ID" value="ADD42801"/>
        <property type="gene ID" value="Snas_3130"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3130"/>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_3_3_11"/>
    <dbReference type="OMA" id="YANNDGM"/>
    <dbReference type="OrthoDB" id="1378040at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_4" evidence="1">
        <location>
            <begin position="40"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="335" mass="35131" checksum="22D52E738752C4EB" modified="2010-04-20" version="1">MPKTRGWSRLTRTITVLIVISLAGLVTSGCGSGSDDRIKIGLITKTETNPIFIEMKDTALIAAEEAGAQLLTATGEFDGDNEGQVSAMENMIAAGVKAILITPSDTKAIVPSVKRAQKLGIAVISLDTPTEPADATDGLYGTDNFRAGEVVGEYAKAKLDGKPAKIATMDLAPGVTVGQLRHDGFLKGFGIKEGDEQLVCEEYTQGDQTKATTAMENCLQAHPDINLVYTINEPAGLGAHTALKAAGRTDKTTLVAIDGGCPGVEATAQGKFDTTAMQFPVKMAELGMDAALEYARTGDRPSGYTDTGVELITDDPVEGLDSKDTDWGAKQCWGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAV7</accession>
    <name>D3QAV7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020324.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5118"/>
    <dbReference type="EnsemblBacteria" id="ADD44753">
        <property type="protein sequence ID" value="ADD44753"/>
        <property type="gene ID" value="Snas_5118"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5118"/>
    <dbReference type="eggNOG" id="ENOG50340XK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1509693_0_0_11"/>
    <dbReference type="OrthoDB" id="1714635at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="178" mass="18900" checksum="FD71A11C78A9324C" modified="2010-04-20" version="1">MGRVVRELGEGVTKYYWYPGQKSDWIKSGICVAAGGAVFLLCYVITKNELVAAVFGASVTCGVGGVYLGRRDVGALSELHDMVAERRAAVVDAGRAAWRATVQGFVVAASAVFVLNMPHEGFIADWVLPVVPALVGAIAHSGGMLYERMNQVAKDNAMADRGEQSEADAEPRELEPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB41</accession>
    <name>D3QB41_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1148</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016429.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1148"/>
    <dbReference type="EnsemblBacteria" id="ADD40858">
        <property type="protein sequence ID" value="ADD40858"/>
        <property type="gene ID" value="Snas_1148"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1148"/>
    <dbReference type="eggNOG" id="COG2229">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077970_1_0_11"/>
    <dbReference type="OMA" id="FMWDELC"/>
    <dbReference type="OrthoDB" id="1438064at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="199" mass="21744" checksum="2A92A80BCB3B9DBD" modified="2010-04-20" version="1">MAYNDDSEAQFPAAIKFLIAGGFGVGKTTFVGAVSEIEPLSTEELITSASIGTDSLDGVDAKSTTTVAMDFGRITLDPERVLYLFGTPGQDRFWFMWDELSDGALGAVVLADTRRLEDCFPAVDFFERRDINFIVAVNEFDGAYRYDTDEVRTALDLKPHIPVVHCDARDSHSATSVLVAFLRHLLLTATSRPGSIVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB59</accession>
    <name>D3QB59_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1166"/>
    <dbReference type="EnsemblBacteria" id="ADD40876">
        <property type="protein sequence ID" value="ADD40876"/>
        <property type="gene ID" value="Snas_1166"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1166"/>
    <dbReference type="eggNOG" id="ENOG5032RDI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072321_0_0_11"/>
    <dbReference type="OMA" id="CVDERFR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="332" mass="36835" checksum="20B0B5DB7C27A250" modified="2010-04-20" version="1">MASTTDPKSPSSRRLTIKIVASLVVGALTYFITEELLGDNKPMAIMTSVFMAGVIFVAQFLYDVDSRMTNLGETMDSHLDNVELKLNSNIDDLGHGAHLVQLLAKSRLPVDNADGLVRDAIEVDANHPELAASLAKAEMVRLGAFMRELRYQKTAAYQGEDRDWLLTLADKSRESIKAISLATVDAGGHNFVDGGLWRSDLGIRYLDLQEMAILERKVRVQRIFVSDLPDDSSKSLLSGIVIPQRDLGIEVRVLHPERIRGTAASKLHDFIVFDDQLVYETTAAARRDPKDTPRTLTTKITVNETAVKDAANFFTLLWDQAEKPADMPPDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBH3</accession>
    <name>D3QBH3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0029 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018426.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3185"/>
    <dbReference type="EnsemblBacteria" id="ADD42855">
        <property type="protein sequence ID" value="ADD42855"/>
        <property type="gene ID" value="Snas_3185"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3185"/>
    <dbReference type="eggNOG" id="COG1739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083552_2_1_11"/>
    <dbReference type="OMA" id="VTVDHQR"/>
    <dbReference type="OrthoDB" id="1777855at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020569">
        <property type="entry name" value="UPF0029_Impact_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="PTHR16301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00910">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0029" evidence="2">
        <location>
            <begin position="15"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="199" mass="20985" checksum="D808CF7CF7D59FA5" modified="2010-04-20" version="1">MRTITRDATAEITVHRSRFICALARLDSETDAKAFIAGRRKLHHAARHHATAWILGPDAANRRSSDDGEPAGTAGAPMLSILAGRDLTDTVAVVTRYFGGVKLGTGGLARAYGDAVTAALDTTGTVERVAAETFTITCPHDVAGRLDAELRAAGHTITATRYDTAAHIDVVTTDTHTLTTWLTTRGLAALHTGTTVIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBN8</accession>
    <name>D3QBN8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3250</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018491.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3250"/>
    <dbReference type="EnsemblBacteria" id="ADD42920">
        <property type="protein sequence ID" value="ADD42920"/>
        <property type="gene ID" value="Snas_3250"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3250"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_0_11"/>
    <dbReference type="OMA" id="PHALWVT"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="68"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="294" mass="31321" checksum="6144C9D44CFB96D2" modified="2010-04-20" version="1">MTRAVRATGPSGWFAAPAVLLFGVFAIVPLFGVAALSFAHWDGLGPISWAGLDNYRAAAADPDTRTAVWLTAKLTVVSVLFQAPVSLLLGVFLAGRQRYRAVLGALFFLPLLFSSAAVALTFVALLDPNFGAGTALGIPALSRDWLGDPQLAFYVVVFVIGWSFIPFHTLIYQAGARQIPAEIYEASRMDGAGAVAQFFRITLPLLKYTIVTSTTLMTVGSLTYFDLIFVLTGGGPGNATRVLPLDMYLTGFRSYEMGQASVIALVLVVVGLVIALGLNRITGASRMESEMEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUQ8</accession>
    <name>D3PUQ8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GntR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5298</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020503.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5298"/>
    <dbReference type="EnsemblBacteria" id="ADD44932">
        <property type="protein sequence ID" value="ADD44932"/>
        <property type="gene ID" value="Snas_5298"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5298"/>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_4_11"/>
    <dbReference type="OMA" id="WMTRENF"/>
    <dbReference type="OrthoDB" id="1045165at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="232" mass="25593" checksum="A822A76E94E66331" modified="2010-04-20" version="1">MASPVLHSAVLDTLGMRITSGELAPGAVLTLEGLRQEFGVSRTVMREVMRLLESMNLVLSRRRVGLVVRPSDEWRVFDPRVIRWRLDGPGRDAQLRTLTDLRSAVEPLAAAGAARHATDADRERIVELAALMRQRGEAGQLEDFLELDIEFHSLLLRASRNEMFAALTEVVAEVLAGRTHHGLMPKPPEPVALDLHEEVARSIHAGADRDAESAMRGLVEEVRAAFADETAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUS6</accession>
    <name>D3PUS6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5316</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020521.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5316"/>
    <dbReference type="EnsemblBacteria" id="ADD44950">
        <property type="protein sequence ID" value="ADD44950"/>
        <property type="gene ID" value="Snas_5316"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5316"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088572_1_0_11"/>
    <dbReference type="OMA" id="HYVSARI"/>
    <dbReference type="OrthoDB" id="2089619at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="215" mass="23449" checksum="3C34E9194CA9DC3F" modified="2010-04-20" version="1">MTDVDPRDLTARARIRDAALRHFGEQGFDRATIRGIAEIAGVSSGLLRHHYGSKEELRDACDAYLAETLAELNDRVRAADASDGVNYVAVAGAAFGPYQKYLSRALAEGRAQPIFDKMVELGGQWLEEMDAKRSDPPTVSRQARAAVSTAMSLSIGILHSHVSRHLGMDVFSPQGADVLVRVLLDLYSHPMLSPDEAAAHLARLDETARPGEEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVM0</accession>
    <name>D3PVM0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43134">
        <property type="protein sequence ID" value="ADD43134"/>
        <property type="gene ID" value="Snas_3470"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3470"/>
    <dbReference type="eggNOG" id="COG3467">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127487_1_1_11"/>
    <dbReference type="OMA" id="LEPWQPG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024747">
        <property type="entry name" value="Pyridox_Oxase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12900">
        <property type="entry name" value="Pyridox_ox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="147" mass="15977" checksum="0007679B456DD397" modified="2010-04-20" version="1">MPISRGQETLTRDECVHLLRTAVFGHIGITVRALPMIVPARFVVDAGRIVIPVSSSSEVLHASQSSIVAFEANDVNTHTGEGWSVLVVGRARVVEEGPEFDRLARLANLMWVTAPETRYIVIALDMVSGRRFGETGDLAEIARPSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVN2</accession>
    <name>D3PVN2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018717.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43146">
        <property type="protein sequence ID" value="ADD43146"/>
        <property type="gene ID" value="Snas_3483"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3483"/>
    <dbReference type="eggNOG" id="ENOG5033P06">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_849699_0_0_11"/>
    <dbReference type="OMA" id="WEEWTIS"/>
    <dbReference type="OrthoDB" id="961000at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048022" evidence="1">
        <location>
            <begin position="30"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="35753" checksum="2FA5C94BDB89452D" modified="2010-04-20" version="1">MKRGWRIAPVIAVLAMLVTGVLVVNSAQAEDERVGLPGGMANFTVAVGKVDAASRANWQRLGTYVFKADGTVSERHWHWTQRRREVRSYTGVRASGCPSRDCDIQTAHGFQSKSAPQQLSGKFAVSGDVVKVTWSDGLWEEWTISQPIEAKLAKLSFKASSFGASHGFGYGSNAGLDKRASMKDVAAVDHGKLRHEYYLWKTDANNKPYVDSGAGGPFWMRDWSLCGGGKCLGGETAKPTEYYLAAPNGSVTDRRDTIWHWVRQLADDRDEYCYTGNSHVKPMMQIIDSDGGFHGWVGAEASLSQTSPGTNADDVGLFEISEFSKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVN7</accession>
    <name>D3PVN7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD linked oxidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018722.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3488"/>
    <dbReference type="EnsemblBacteria" id="ADD43151">
        <property type="protein sequence ID" value="ADD43151"/>
        <property type="gene ID" value="Snas_3488"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3488"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_10_2_11"/>
    <dbReference type="OMA" id="GYPFPGG"/>
    <dbReference type="OrthoDB" id="330793at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="37"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="474" mass="51278" checksum="8A2326A6A910A09C" modified="2010-04-20" version="1">MKTVSFGQLGDRLHGRLILPGEPDFDSVRKWFIGRFTETVPQAVARCADTRDVAEAVAFARAKDIPFALRSGAHSFAEYSMSEGLVIDLDGMDEVRVSPDGATVTAGPGTRIGPLAEVLARHGRVVPVGWCPMVAVAGASMGGGFGPLGRYYGLGCDHLVGAEVVLADGRIVRTSETTEPDLLWALRGAGAGNFGAVTSLTFRTRPAVPAVHFAAWWKPEDGAAVIDAWQRWAPTAPSRVNAELILRCWPDPDEPATLSVFGLIVGASPRAAAERVAELADLVGISPERVTYTELTAEELPNHHTFAGEPTSHNKLGGRPGDAEPGVRFVKSEFFDAAVPLDAIADLVDGLLRDRVASQQREFEFIPWGGAIGEPAPGDTAFVHRSPRFLVEHSVQAYGSAELKRASHEWVTASKATLHRWGNGHVYQNYPEPDLPDWDIAYYGDNLHRLHAVKAAYDPDGVFRYEQSLRADGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVW7</accession>
    <name>D3PVW7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Heat-inducible transcription repressor HrcA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hrcA</name>
        <name evidence="8" type="ordered locus">Snas_5456</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HrcA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020659.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5456"/>
    <dbReference type="EnsemblBacteria" id="ADD45088">
        <property type="protein sequence ID" value="ADD45088"/>
        <property type="gene ID" value="Snas_5456"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5456"/>
    <dbReference type="eggNOG" id="COG1420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050019_2_0_11"/>
    <dbReference type="OMA" id="DYPGTMG"/>
    <dbReference type="OrthoDB" id="1510750at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00081">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002571">
        <property type="entry name" value="HrcA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021153">
        <property type="entry name" value="HrcA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023120">
        <property type="entry name" value="WHTH_transcript_rep_HrcA_IDD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34824">
        <property type="entry name" value="PTHR34824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01628">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005485">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00331">
        <property type="entry name" value="hrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0678">Repressor</keyword>
    <keyword evidence="3 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="7">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="HrcA" evidence="6">
        <location>
            <begin position="105"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="340" mass="37117" checksum="A1470FCFF0D5F95E" modified="2010-04-20" version="1">MTMDDRKLDVLRAIIEDYVTTKEPVGSKSLVHRHALGVSSATIRNDMAVLEEEGYIRQPHTSAGRVPTNRGYRLFVDRLSKIKPLTAAERRAVHRFLDDAVDLNDVVHRTVRLLAQLTRQVAVVQYPSLSRSSVRHLELVPLVANRLMLVMITDTGRVEQRVVDLPEDLPEEDVLTLRTQINDKLVGIRLTETPTQVRTLVEEASPQLRPAMTALSTVLLETLVERGEERIAVAGTASLTLHAVDFAGSLRPILEALEEEVVLLKLLGEIDSGSTLNICIGEENKIAGLDGTSVVSTGYGPAGSVVGGLGVVGPTRMDYPGTIAAVRTVARYVSQILAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWA9</accession>
    <name>D3PWA9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016837.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1563"/>
    <dbReference type="EnsemblBacteria" id="ADD41266">
        <property type="protein sequence ID" value="ADD41266"/>
        <property type="gene ID" value="Snas_1563"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1563"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080440_0_0_11"/>
    <dbReference type="OMA" id="AGLDLWI"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="207" mass="21766" checksum="D2EEAE9F0EB74295" modified="2010-04-20" version="1">MGDTRTKLLDGTVEVLRTKGLAGVSARAVATAAGANQALVFYHFDSVDNLLAEACERAAAQRVERFRAGFARVASLTDLLRLGRSIHEQERRAGNVDVLAQLLAAGQADSLAAKAAAAGLALWVDEVEAVLRRVLDPTPVADFIEPRALAKAVSAAFIGIELYEGVDSEGADAAFTALEQLGALAAILEDAGPLTRAALRHKLRRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWH8</accession>
    <name>D3PWH8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018771.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3538"/>
    <dbReference type="EnsemblBacteria" id="ADD43200">
        <property type="protein sequence ID" value="ADD43200"/>
        <property type="gene ID" value="Snas_3538"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3538"/>
    <dbReference type="eggNOG" id="ENOG50331Z4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_170431_0_0_11"/>
    <dbReference type="OMA" id="VRISRMM"/>
    <dbReference type="OrthoDB" id="2040341at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="104" mass="10974" checksum="BD620CAB4D087A23" modified="2010-04-20" version="1">MDVQELFDDIAADLAQRGAIAGAMFGKRALKANGKAFACLKDDALAFRLGAGTPAHTDALKLPGATLFDPSGKDRPFKDWVAVPAAQQSQWGRLARTALTSLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWP9</accession>
    <name>D3PWP9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018842.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43271">
        <property type="protein sequence ID" value="ADD43271"/>
        <property type="gene ID" value="Snas_3611"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3611"/>
    <dbReference type="HOGENOM" id="CLU_1089514_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="255" mass="28384" checksum="FB216A283FFC9FD9" modified="2010-04-20" version="1">MATPRNTITRDIDGEACTDFDGVCAILDRAPSTVRTYIPANPDLLAPVRNGTYIDGRKWYRLTGVHAFADILAAKTHANKPLSPTPGGDPEDMLSRDQVAHVWHASPTTITRYANKARHQWIKRHPRPLMPPPRAGYDPDHPYASGPAHWEWRRRDIVEHPRPGRGAAGGRRPSAPAPPPPTAPEALLDYRQAAHVQGIPVATMRTKLARAKPQWIAQHPAPSMPPPDHGFDIDNPDASKPSQWRWYRRTIDPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWQ6</accession>
    <name>D3PWQ6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3618</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018849.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3618"/>
    <dbReference type="EnsemblBacteria" id="ADD43278">
        <property type="protein sequence ID" value="ADD43278"/>
        <property type="gene ID" value="Snas_3618"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3618"/>
    <dbReference type="eggNOG" id="ENOG5032P66">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183116_0_0_11"/>
    <dbReference type="OMA" id="GVFCDES"/>
    <dbReference type="OrthoDB" id="1910120at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="94" mass="10566" checksum="DE316A037D823FB9" modified="2010-04-20" version="1">MIVYPLWHVGHHNEAGDGGSTVHVDASGVFCDESDGDDVKLLGIYSTVERVEERIRQARLLPGFRDEPECFYFDARDLDEDAWAEGFVRVPPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWT4</accession>
    <name>D3PWT4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018877.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3648"/>
    <dbReference type="EnsemblBacteria" id="ADD43306">
        <property type="protein sequence ID" value="ADD43306"/>
        <property type="gene ID" value="Snas_3648"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3648"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_15_2_11"/>
    <dbReference type="OMA" id="RAVEQCE"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="40"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="158" mass="17810" checksum="BC54331EB1F9F052" modified="2010-04-20" version="1">MSRVNTSDVPNPRAAANGGPALFRLVRFWSRRWTNQPLTTSTPDGDTRRVQNIQVVEAVAAARDEATVTTVAEQLGLDHSGASRMVRDAVAAGHLHRGESNQDRRRVALRLTDDGRQLLTASHDWQRRCFDQLTATWDDTDRRRFAAYLQRLADETLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWU7</accession>
    <name>D3PWU7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exodeoxyribonuclease 7 small subunit</fullName>
            <ecNumber evidence="3">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Exodeoxyribonuclease VII small subunit</fullName>
            <shortName evidence="3">Exonuclease VII small subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">xseB</name>
        <name evidence="4" type="ordered locus">Snas_5540</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the XseB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020742.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5540"/>
    <dbReference type="EnsemblBacteria" id="ADD45171">
        <property type="protein sequence ID" value="ADD45171"/>
        <property type="gene ID" value="Snas_5540"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5540"/>
    <dbReference type="eggNOG" id="COG1722">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145918_0_2_11"/>
    <dbReference type="OMA" id="AKVCQRW"/>
    <dbReference type="OrthoDB" id="2057189at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00337">
        <property type="entry name" value="Exonuc_7_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003761">
        <property type="entry name" value="Exonuc_VII_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037004">
        <property type="entry name" value="Exonuc_VII_ssu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34137">
        <property type="entry name" value="PTHR34137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02609">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006488">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116842">
        <property type="entry name" value="SSF116842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01280">
        <property type="entry name" value="xseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3 4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="66" mass="7239" checksum="397D0E15D41FE3F3" modified="2010-04-20" version="1">MDDEALDYEAARAELVSVVERLEAGGTTLEDSLALWERGEKLADLCQSKLDGARARLDKATESREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXE7</accession>
    <name>D3PXE7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016981.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1711"/>
    <dbReference type="EnsemblBacteria" id="ADD41410">
        <property type="protein sequence ID" value="ADD41410"/>
        <property type="gene ID" value="Snas_1711"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1711"/>
    <dbReference type="eggNOG" id="COG0546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_19_2_11"/>
    <dbReference type="OrthoDB" id="1484726at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="219" mass="23714" checksum="52EFD40A82A4817F" modified="2010-04-20" version="1">MAITHVVWDWNGTLFDDARALIDTTIEVFAELGLPAVTVERYQAVHTQPIDEFYRRLLGGLVDGELLRRIHARFEVAYARRRPGLALTADTVAALESVEASGLSQSVLSMHPHDRLTALVERFGIAGRFVRVDGQRGADAGFKAAHLAGHLERLGLSGERVLVVGDSVDDAAASEDVGARCVLYRSGLHSVEALRRADVPIADTLREALTLGLRKAGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXE8</accession>
    <name>D3PXE8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_1712</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016982.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1712"/>
    <dbReference type="EnsemblBacteria" id="ADD41411">
        <property type="protein sequence ID" value="ADD41411"/>
        <property type="gene ID" value="Snas_1712"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1712"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033532_3_1_11"/>
    <dbReference type="OMA" id="TEAFSWL"/>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="164"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="396" mass="40187" checksum="7B86A03D4C009F2B" modified="2010-04-20" version="1">MTTRTASPVGEILRSRHVLRLLSSCLVGRLPTGMAALAIILWVRSHGGDYRLAGLLAALYAVSVAVCGPIMGRLIDRTRQAPFLVGGAVVAGAAFVALSMVDPVTAPATAGFVAVVAGAATPQLEPCLRVLWEDVTSGERQVRAAYALDAATQELIFVCGPVVVLAAVGLAGTSAGLIAAAVVGLAGTLWFASAAPARAWRGSPVARHWAGPLRSGNLVRLFVALVCMGCAVGAFTVGVTARADGLGTPGAAGWLLALNAVGALASGLAYTNVGVARRDDRRLALAMVVMALAYLPLLFADGLVPLAVLAFVCGAPLPVALTSSFALVARIAPPGTLTESHAWMITSFGVGYAAGTGLAGTVVDAIDTPTAFLLATVAAAVSALWTVPRLLPRRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXF3</accession>
    <name>D3PXF3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Microcystin LR degradation protein MlrC-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1717</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016987.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1717"/>
    <dbReference type="EnsemblBacteria" id="ADD41416">
        <property type="protein sequence ID" value="ADD41416"/>
        <property type="gene ID" value="Snas_1717"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1717"/>
    <dbReference type="eggNOG" id="COG5476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028172_2_0_11"/>
    <dbReference type="OMA" id="FKEFPHT"/>
    <dbReference type="OrthoDB" id="421877at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009197">
        <property type="entry name" value="MlrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010799">
        <property type="entry name" value="MlrC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015995">
        <property type="entry name" value="MlrC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07364">
        <property type="entry name" value="DUF1485"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07171">
        <property type="entry name" value="MlrC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012702">
        <property type="entry name" value="UCP012702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1485" evidence="2">
        <location>
            <begin position="7"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="MlrC_C" evidence="1">
        <location>
            <begin position="294"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="482" mass="51500" checksum="CF76A9BEC33DC3EB" modified="2010-04-20" version="1">MGERKWRIAVGGIHIESSTFSPNLAGPSDFAVTRGDDLLNRYDSLPESARWLPLVHARAMPGGAVEAAFYDDIATEFLDRLRRAHEAEPLDGVYLDIHGAMSVDGRRDAEGRLAAEVRRVVGPDVLVSASMDPHGNVSRALVDNVDLLTSHRMSPHEDWKLTMARAQSKLVECLDAGVRPRRAWVTVPVLLPGEKACTRDDPAKRLYGMLPAIEACDGVVDAAIWIGYAWADEPRCQAAVVVSGTDTDLIQAKAAELARAWWDARAEFDFSTRATDADTAIAEALASPKRPFFVSDSGDNPTAGGSDDVPYFLGRLLATPELATGEASAIWVSVVAPDAVVACAEAGIDGEVECAVGGALGWGDTLSLKGRVVNLVDDADGGTIAVVVSGGVSAVLTSRRKAFHYIEDFTALGLDPAKVDLTVVKIGYLVPDLFDAAAGWVLALSPGGVDQHIVRLGHRHVDRPMYPLDPDMSDPDLTPVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXF8</accession>
    <name>D3PXF8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016992.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1723"/>
    <dbReference type="EnsemblBacteria" id="ADD41421">
        <property type="protein sequence ID" value="ADD41421"/>
        <property type="gene ID" value="Snas_1723"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1723"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052868_1_0_11"/>
    <dbReference type="OMA" id="RGSYVGC"/>
    <dbReference type="OrthoDB" id="1518440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026669">
        <property type="entry name" value="Arsenite_MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43675">
        <property type="entry name" value="PTHR43675"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="94"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="265" mass="27169" checksum="DCF852073D53F211" modified="2010-04-20" version="1">MTTIDNTSCCGPTAIPEPTDPVALRERVRESYAAAARKVNEGGGGCCGPATTDDLDFFGPEAYAAADRDSLPDAAVAASLGCGNPVAVADLAEGETVLDLGSGGGIDVLLSAKRVGPTGRAYGLDMTDDMLELARANASKAGATNVEFLRGEIEEVPLPDASVDVIISNCVINLSTDKPAVFAEMTRVLRPGGRIGLSDVVAADTLSPSDRAARGGHVGCIAGALSFEEYREQLAAAGFGQISITPTHEVTDGMHSAIVRAHKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXY2</accession>
    <name>D3PXY2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020882.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5681"/>
    <dbReference type="EnsemblBacteria" id="ADD45311">
        <property type="protein sequence ID" value="ADD45311"/>
        <property type="gene ID" value="Snas_5681"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5681"/>
    <dbReference type="eggNOG" id="COG1213">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_5_0_11"/>
    <dbReference type="OMA" id="AYSLWCA"/>
    <dbReference type="OrthoDB" id="1557977at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="1">
        <location>
            <begin position="3"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="242" mass="25895" checksum="9B783F2101D58A93" modified="2010-04-20" version="1">MRGVVLAAGQGQRLKPDTDDLPKTLLPVDGDVTILDIALRNLAAAGVGEVGIVVGFAAHAIEARVEALRERYGLTIELIHNDRTDWNNAYSLWHARDFYAQGALLVNGDTVHPGSVEKTLLAAEGDGILLATDAVKELTDEAMKLQCGADGVVTTVTKQMPVESAYGEYIGVSRIGADIAAELTDALVRTYTSDPNLYYEDAFQLLADAGPNVHAVPIGAVDWVEVDNHADWAVAREVACRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY39</accession>
    <name>D3PY39_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020939.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5738"/>
    <dbReference type="EnsemblBacteria" id="ADD45368">
        <property type="protein sequence ID" value="ADD45368"/>
        <property type="gene ID" value="Snas_5738"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5738"/>
    <dbReference type="eggNOG" id="COG3315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067079_1_0_11"/>
    <dbReference type="OMA" id="VQNTHEV"/>
    <dbReference type="OrthoDB" id="1186918at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006764">
        <property type="entry name" value="SAM_dep_MeTrfase_SAV2177_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04672">
        <property type="entry name" value="Methyltransf_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017393">
        <property type="entry name" value="MTase_SAV2177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="280" mass="31026" checksum="9928682EC8ECA096" modified="2010-04-20" version="1">MTASDGATPNEGYQPPSEFDINEPTIARVYDALLGGKDNFAADRAGADTYLKYVPDSGKCAKENREALVKGVQYLVRQGIDQFLDIGSGLPTVKNTHEAAQEINPEAKVVYVDNDPIVLAHGRALLATNNSTTVVTADLRRPNEILENEDVQRMLDFSRPIALMIVGLHMHFHDDEQPDEWVRTILDTMPAGSYLFITDFVDTGEPLQKAMEQAGLESLGNGWIRTPERIKEHFLGLPLEPPGLDFLARWFPGEPDRVLTPAEDLEPYQRILMAGIAKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY51</accession>
    <name>D3PY51_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020951.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5750"/>
    <dbReference type="EnsemblBacteria" id="ADD45380">
        <property type="protein sequence ID" value="ADD45380"/>
        <property type="gene ID" value="Snas_5750"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5750"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_4_2_11"/>
    <dbReference type="OMA" id="SHYDTNV"/>
    <dbReference type="OrthoDB" id="1306955at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="6"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="176" mass="19371" checksum="EB2950A05DB50F06" modified="2010-04-20" version="1">MTFTATVFIGTSLDGNIARLDDDLDWLTSRGEQAGDMGFFEFLDSVDAVAMGRNTYDKVIGFGEENWPFGDRHVGVLSTTLPEDADPRVTVYRDLDDLVADFDKRGITHVYPDGGRLIQSFVRAGRIDRFIISVAPVLIGAGHRLFGELSHDVPLRLDSVADVGGGFAQLRYTVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY72</accession>
    <name>D3PY72_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020972.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5771"/>
    <dbReference type="EnsemblBacteria" id="ADD45401">
        <property type="protein sequence ID" value="ADD45401"/>
        <property type="gene ID" value="Snas_5771"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5771"/>
    <dbReference type="eggNOG" id="ENOG5032VCE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121293_0_0_11"/>
    <dbReference type="OrthoDB" id="1733975at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="171" mass="19495" checksum="181D28FB285CFE13" modified="2010-04-20" version="1">MGEITDRVDRMVVRATSPDNNIMAAFTGGRTLEIQFRPGTYRAYSRHALQHQLSQLGPLVFTGYRRGLNQVIQSVTGSTEPASEDWDANRRRYRQAQEKLVARAFSPNRRLRAQAEGLLHWTVEIKDGTLAELSEADFCREASKLVDRILNDHNIKIGELQKRHLGLRAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY79</accession>
    <name>D3PY79_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1748</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017017.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1748"/>
    <dbReference type="EnsemblBacteria" id="ADD41446">
        <property type="protein sequence ID" value="ADD41446"/>
        <property type="gene ID" value="Snas_1748"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1748"/>
    <dbReference type="eggNOG" id="ENOG5033TZK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1085077_0_0_11"/>
    <dbReference type="OMA" id="CICATER"/>
    <dbReference type="OrthoDB" id="1801606at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="240" mass="25613" checksum="0A92F1F3EBB7C56D" modified="2010-04-20" version="1">MNPPSYAARIRPVIDRVYTGLRRAAMPRQRAVYEKFGATPGFESSFYFGLLARPMSAAGFAAATTYSGADMTGEREQGVATVDDDGNWGLTERGRELALAVQWAVADGAEEAWGQTPIATMPGLSVVPRLAELVGRLLDAGRESGGPAFRALTPVFEPADATPSLLLASRLGALRHHRGDAHRAAWQGRGLSLDELRELSGGAQRQAIEDETDRLDAPIYAVLTADERLELLAGLGALPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYA7</accession>
    <name>D3PYA7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(+) diphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1777</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.1.22" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017045.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1777"/>
    <dbReference type="EnsemblBacteria" id="ADD41474">
        <property type="protein sequence ID" value="ADD41474"/>
        <property type="gene ID" value="Snas_1777"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1777"/>
    <dbReference type="eggNOG" id="COG2816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_0_4_11"/>
    <dbReference type="OMA" id="HIRRCPA"/>
    <dbReference type="OrthoDB" id="1435118at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000210">
        <property type="term" value="F:NAD+ diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="143"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="282" mass="30489" checksum="A5999952B5AB5BE0" modified="2010-04-20" version="1">MRPQLSRAVLDRAAHRRADPAWLDEAWTRAKVLVVDPASGNVAVTGEPPELVYTEPDAAPDGDRLYLGGEKQPYFAVAAPVEAGMGLREAGPLLSDFDVGVLTEAVALVRWHADHTFHAATGELTEVDEGGWSRRAGDKVSWPRTDPAVMVIITDGADRVLLANGKGWPADRFSCVAGFVEPGESAEAACHREVAEEVGVDIDGLTYVASQPWPYPRSLMLAFEAVADPAQDIVVEPAEIAAARWFDRAELRAALSGETAPLRVPPSISIARFLMERWLTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYB2</accession>
    <name>D3PYB2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="6">1.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1782</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017050.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1782"/>
    <dbReference type="EnsemblBacteria" id="ADD41479">
        <property type="protein sequence ID" value="ADD41479"/>
        <property type="gene ID" value="Snas_1782"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1782"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_0_11"/>
    <dbReference type="OMA" id="HGIGYYP"/>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043878">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="31"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD41479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="507" mass="54849" checksum="55DB450B932BD37E" modified="2010-04-20" version="1">MTTYAAPGTSGSAVAYASRYDHFIGGEYVPPANGEYFDNPTPVTGASFTEIARGTAADVERALDAAHGASVAWGKTSAAERAVLLNRVADRIEQNLEMLAIAETWDNGKPVRETLAADLPLAIDHWRYFAGAIRAQEGGISEIDADTVAYHFHEPLGVVGQIIPWNFPLLMATWKLAPALAAGNAVVLKPAEQTPASIHLLIGLIADLLPPGVVNIVNGFGVEAGKPLASSPRVAKVAFTGETTTGRLIMQYASQHLRPVTLELGGKSPNIFFTDVAAAHDDFYDKALEGFAMFALNQGEVCTCPSRALIQSRIYDGFVSDAVERTSRITQGNPLDTDTMIGAQASNDQYEKILSYIDIGRKEGARVLCGGEPNDLGGELSQGFYVQPTIFEGNNKMRVFQEEIFGPVVSVTRFDDYDDAIKIANDTLYGLGAGVWSRDIATAYRAGRDIQAGRVWTNCFHAYPAHAAFGGYKQSGIGRENHKMMLEHYQQTKNLLVNYSPKAQGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYG0</accession>
    <name>D3PYG0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidoglycan-binding domain 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1831</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017098.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1831"/>
    <dbReference type="EnsemblBacteria" id="ADD41527">
        <property type="protein sequence ID" value="ADD41527"/>
        <property type="gene ID" value="Snas_1831"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1831"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_908438_0_0_11"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005073">
        <property type="entry name" value="Peptidase_M74"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03411">
        <property type="entry name" value="Peptidase_M74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048694" evidence="2">
        <location>
            <begin position="31"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="3">
        <location>
            <begin position="44"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="3">
        <location>
            <begin position="108"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD41527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="323" mass="34408" checksum="9C8299DDF9154E61" modified="2010-04-20" version="1">MKRRHLIGSLLAVAVAAALTWTLVPGSASAYPNAAFHMQNLGNRGADTLSVQHLLAQAGHQVEATGAFDAATESAVKKFQESKGLDADGIVGPKTWEALAPNLETGASGEAVKALQVQLNAKQRLSLEVNGTFDDALAGEVRKFQEHAKISATGAVNVETWRNLVWHFDYPDFEAGTLCDQDPDGNGKADWGTASAVGQLEAGAKTFAESGNGPLPVGDIGFEHGGDIPGHGSHEVGLDVDVWPIRGDSKQCEADRITWESAEYDRDATRQLVKDIRAAASGHVVFILFNDPKLIAEGLTSEYANHDNHLHIRYCEVGGGYAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ06</accession>
    <name>D3PZ06_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">Phosphoenolpyruvate carboxylase</fullName>
            <shortName evidence="9">PEPC</shortName>
            <shortName evidence="9">PEPCase</shortName>
            <ecNumber evidence="4 9">4.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ppc</name>
        <name evidence="11" type="ordered locus">Snas_5805</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>oxaloacetate + phosphate = hydrogencarbonate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:28370"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the PEPCase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.31" evidence="4 9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5805"/>
    <dbReference type="EnsemblBacteria" id="ADD45435">
        <property type="protein sequence ID" value="ADD45435"/>
        <property type="gene ID" value="Snas_5805"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5805"/>
    <dbReference type="eggNOG" id="COG2352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006557_2_0_11"/>
    <dbReference type="OMA" id="PWVFGWT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00595">
        <property type="entry name" value="PEPcase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022805">
        <property type="entry name" value="PEP_COase_bac/pln-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018129">
        <property type="entry name" value="PEP_COase_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PTHR30523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00781">
        <property type="entry name" value="PEPCASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="7 9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="9 10">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD45435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="914" mass="100376" checksum="4BA98DF84CEA815E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZ42</accession>
    <name>D3PZ42_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase (Rotamase)-cyclophilin family-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5842</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021042.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5842"/>
    <dbReference type="EnsemblBacteria" id="ADD45471">
        <property type="protein sequence ID" value="ADD45471"/>
        <property type="gene ID" value="Snas_5842"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5842"/>
    <dbReference type="eggNOG" id="COG0652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_816140_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="3">
        <location>
            <begin position="138"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="340" mass="35018" checksum="2D51CAC77AFBCEA0" modified="2010-04-20" version="1">MDAKSDDDVTEPNPSADDVTEIRPAVQAPDPTPDTDRKAARKEARRQPLNPDDPEPTWLARGSGGRTIVGIVLVLVMVAGIAALGWWLFEPASAESTDDGKLTSEDCRVSEAKDEAATVRLPPSLGKTEPRATATVTTNVGELTVLLFGDVSPCGVSGFEYLTRQGFYANSPCYRLTTQQTDPTVTLRCGDPTGTGKGGPGFRYQAEDAFTGEVGRDYVALINDRKGMAGGSFAFVRGESKPTAALSVIGQVISGHGVLDQIGAAAGVDPYDDEPAQPVVIQKITIKTGTVTLPPSDNGSSPSSSGVPTTSGTGTATPSGSGQPSSGGSSSSGGGIDFPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZD2</accession>
    <name>D3PZD2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017177.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1910"/>
    <dbReference type="EnsemblBacteria" id="ADD41606">
        <property type="protein sequence ID" value="ADD41606"/>
        <property type="gene ID" value="Snas_1910"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1910"/>
    <dbReference type="eggNOG" id="COG0111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_0_11"/>
    <dbReference type="OMA" id="VQMAEYV"/>
    <dbReference type="OrthoDB" id="1435073at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh_C" evidence="1">
        <location>
            <begin position="110"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="35899" checksum="946550AECF1D3FD8" modified="2010-04-20" version="1">MLGEDSPVLTVLHSVDQPPDLERIEKYATIRYTDETGLTQALPGADALFVYDFLSTALPGAWHAADRLSWVHIASAGVDPVLFPGLRDSDVTLTNSRGVFDDAIAEYVLGVILAFAKDFARSLRLQEAARWQHRETERVAGQHVMVMGTGPIGRAIARMLRAVGMRVSGVGRTRRENDPDFGVVHPSTELVEHLPEADYVVAVAPLTEQTKGAFDARAFAAMKPTARFVNVGRGELVITKDLIAALRSQQIAGAALDVFDVEPLPSDSPLWMMQNVLVSAHMSGDVIGWRNILVERFIENFERWRTRQPLHNVVDKQLGYVPSPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZF5</accession>
    <name>D3PZF5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1933</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1933"/>
    <dbReference type="EnsemblBacteria" id="ADD41629">
        <property type="protein sequence ID" value="ADD41629"/>
        <property type="gene ID" value="Snas_1933"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1933"/>
    <dbReference type="eggNOG" id="COG3023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_841759_0_0_11"/>
    <dbReference type="OrthoDB" id="1584918at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14488">
        <property type="entry name" value="CBM6-CBM35-CBM36_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033803">
        <property type="entry name" value="CBM6/CBM35/CBM36-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="2">
        <location>
            <begin position="51"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="330" mass="36307" checksum="FC5978E63F38FF4A" modified="2010-04-20" version="1">MGLGASPAFAHEEGGRGDDKGDADRPEEAGPESTAVDYQGASWLAAHKANYTNASRPKSDPINKVVIHTMQGTASGTKAWFRNPKSEVTTHYLVSSSKGSVTQMVHESDIAWHAGNWDYNKTSIGIEHEGYVQDPKKWYTTNMYESSARLVRSICDRYNIPMDRKHIIAHSEVPGATHTDPGKGWNWDRYMDLVRESKTQSFSMDNDSAGVSASDAWQRAKVPNGRDYAYASPVAKSDPLWYTVDLPSTGRYRVEVRYPASPDNNTQTPYLVATSSGFESVYVDQTTGGDTWKSIGSFNLKAGEKPTVGVSRWTGTQGRVVADGVRLVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZW4</accession>
    <name>D3PZW4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase involved in chromosome partitioning-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019222.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3999"/>
    <dbReference type="EnsemblBacteria" id="ADD43651">
        <property type="protein sequence ID" value="ADD43651"/>
        <property type="gene ID" value="Snas_3999"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3999"/>
    <dbReference type="eggNOG" id="COG0455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003609_6_0_11"/>
    <dbReference type="OMA" id="IMHSAMN"/>
    <dbReference type="OrthoDB" id="2013820at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="2">
        <location>
            <begin position="86"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="334" mass="36317" checksum="C13D7BEDAE2E06E1" modified="2010-04-20" version="1">MGTTDGWSAKRSEQTPRWRTLLSRSRQRGDDTATLSPPPQQDYPSSEVVPPPRQPLAWGAAEPSPGRDLSRHPALKELRRDLGRPRVIAFVNPKGGVHKTTATVLTAAALGSARGKGVIAWDDNELRGTLGLRAGTARHARTIRHLVNDLAQVEAAGTQLAEIADDYLRHSADGSFDVLAGDEDPKLAGKLDPETVLRVLDILTRTHDIICIDTGNNVESENWRTVVSNADQLVVTSVPREDAAFTADWMLDLLVSDGYVDLVANAVTLLSCPTPRPGTLLDDLTAHFKSRTRDVAVVPYDPTLEPGSAIKYSQLRDTTQDAWLNAAATIIRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZY3</accession>
    <name>D3PZY3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019241.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4018"/>
    <dbReference type="EnsemblBacteria" id="ADD43670">
        <property type="protein sequence ID" value="ADD43670"/>
        <property type="gene ID" value="Snas_4018"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4018"/>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073856_0_0_11"/>
    <dbReference type="OMA" id="GRACDWS"/>
    <dbReference type="OrthoDB" id="1180964at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049599" evidence="2">
        <location>
            <begin position="34"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="331" mass="34523" checksum="7CD722587DB2324D" modified="2010-04-20" version="1">MTRQSTKRRAFAPVAVGVAVFTVLAAGPVPAFADPEVNEKDVDGELQEAIEEYLDAKETLETTDDRQDKIKSEIADSKKQVKRLGIQAGDFAAAAYTSGGDLRASTIVLTAGSPRTAIQTLALVSYLGEQTGAKIDELTEAREDLEAEKKSLSDEKDKAEKALGKLESARDKAARAVASGGGNSAQGPSASDAPAAEPAPAGLSGGCTEDDPTPADGCLTPRTLHALEQAQIAGFQRYVSCYRGGGNGEHPQGRACDFSAEPGGFGGDATGAAKAYGDNLAAWLVDNADALGVMYVIWYRQFWDPSQGWTTYSGGGGPSGAHTNHVHLSMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZY5</accession>
    <name>D3PZY5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_4020</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4020"/>
    <dbReference type="EnsemblBacteria" id="ADD43672">
        <property type="protein sequence ID" value="ADD43672"/>
        <property type="gene ID" value="Snas_4020"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4020"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_33_11"/>
    <dbReference type="OMA" id="MRWALNR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048131" description="Histidine kinase" evidence="7">
        <location>
            <begin position="32"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="169"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="229"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="444" mass="47294" checksum="C275B01CF17DFD6A" modified="2010-04-20" version="1">MRWALAKVAIASTLMVALAFCIPLGMVVRQVAEERALSQARDAAGAMVTVLAATEDPVVLRRAVSSESSGVGKRIAVHLNGEQVIGKSHVETSLIRKVARQARTSTETLPDGVAYLRTVLLPEDRVAVIEVYVPDKLLTKGVNTAWLTLAGIAVALVGVSVLMADRLGARVVRSTRTLADATSRFGAGDLSVRVDPSGPDELQDAGLAFNMMADKVVRLVDGERELAADMSHRLRTPLTALRLDAESLGGGADARRMRASVDALEAEVDAVIAGARRSITDRSGQRCDVAEVVRERISMWSVLAEDHGRRYRVVGLRDSLWVNISRDDVMSCVDALVGNVFAHTPQDAPFSLELNSATGRFIVEDGGPGIADPMTALTRGESGAGSSGLGLDIVARISKAAGGRLHIGRSALGGARIVWTFGDAVYREPQDNGNGRRARTHRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q039</accession>
    <name>D3Q039_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidoglycan-binding domain 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5941</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021139.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5941"/>
    <dbReference type="EnsemblBacteria" id="ADD45568">
        <property type="protein sequence ID" value="ADD45568"/>
        <property type="gene ID" value="Snas_5941"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5941"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057459_1_0_11"/>
    <dbReference type="OMA" id="ERTMTPP"/>
    <dbReference type="OrthoDB" id="1968187at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="3">
        <location>
            <begin position="150"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="381" mass="39387" checksum="6EBB869FF18074F5" modified="2010-04-20" version="1">MEADISVETAEPTRSRRRRGRGRGKKIVITTVVVLAAAAAGVAAIGVDKVMGALGVSGFGGKAAASDTAPPATTEVARQTLRQTQDADGELGYGPTSTAASRKPGTVTWLPDSGDTIKRGDPLFAVDTMPTTLMYGTAPAYRDMKVGDEGSDVKQLEKNLAKLGYDGFTVDKEFTADTATAVREWQDDLGLKETGTVTLGQVVFADGAIRIDSFEAEVGLATGPDKSVLSYTGTDKVVAIELEADDQQLAKEGDKATVSLPNGETADGEITDVSSLIKPPSGQQEESETVIQVLVSLDDDSVAKGLSQAAVTATFTASEREDVLTVPVAALVALEGGGFGVEVVDGDKTEQVEVETGLFAAGRVEISGSGIDEGTVVGVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0C8</accession>
    <name>D3Q0C8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015363.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0070"/>
    <dbReference type="EnsemblBacteria" id="ADD39792">
        <property type="protein sequence ID" value="ADD39792"/>
        <property type="gene ID" value="Snas_0070"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0070"/>
    <dbReference type="HOGENOM" id="CLU_969464_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="287" mass="31323" checksum="3F365BF1D7E4BD8E" modified="2010-04-20" version="1">MTNMTGAIHEAVDAIGTAIIYAESRKGSWVFEQQEWLDFVRELSPLMHHQYGRLANCDPSPAKAASKRIESGKTSLAKNANPNGSLESQTKRIKKLCETWRSDGGYAFHSHIGKMEFALLHQQEMAAVLSSLMELHSSHVLATQEDLLNIANLTIDSLERHGYDIQQKERQKLGAILDTLVSVASGGIVGSLGSGAAKAVGEAVSGIKGSSAVSAAMQLPTDDTMLIIKTMKRKVDQLIEQTTAQQSQIRVALTSVFEAYVDKPIMLPPEVATGTLSDQDWRYATRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0D2</accession>
    <name>D3Q0D2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0074</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015367.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0074"/>
    <dbReference type="EnsemblBacteria" id="ADD39796">
        <property type="protein sequence ID" value="ADD39796"/>
        <property type="gene ID" value="Snas_0074"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0074"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_22_0_11"/>
    <dbReference type="OMA" id="IMAIRFE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014303">
        <property type="entry name" value="RNA_pol_sigma-70_ECF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02957">
        <property type="entry name" value="SigX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="19"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="114"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD39796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="294" mass="32094" checksum="0E7524EFA399143C" modified="2010-04-20" version="1">MTAGRAETGPDAATDAFVAHRNLLFTVAYELLGSAVDAEDVLQETWLRWADVDLDTVRDHRAYLVRIATRQALNRLRTLSRRKESYVGPWLPEPLLTTPDVAEDVELADSLSTAMLLVLETLTPTERAVFVLRDVFALDYDEIAEAVDKTPAAVRKVAHRARSHVAARRPRGEVSPAQSRAALEAFRSAVATGDLQGLVDILAPDMVMLSDGGGIVTALPNPIVGADKVLRLFAASLDTFLRGATLEPVRVNGFPALLMRVCGKLDGVLTLRLDDGLVSGLYYVRNPEKLSRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0K1</accession>
    <name>D3Q0K1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017308.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2042"/>
    <dbReference type="EnsemblBacteria" id="ADD41737">
        <property type="protein sequence ID" value="ADD41737"/>
        <property type="gene ID" value="Snas_2042"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2042"/>
    <dbReference type="HOGENOM" id="CLU_2095370_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049608" evidence="1">
        <location>
            <begin position="30"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="116" mass="12299" checksum="FCB6F2F140CCA4AC" modified="2010-04-20" version="1">MLRRKLPAGLVTGFAAASLVLASAGVASADEGDGAVCETQEVVVKGRSVPVMLEPSVDAPRLYTASKGEFHKCSAVKVGGEHNECGASKSNVWVILTDYKRFDTYIPSHCVADVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0K8</accession>
    <name>D3Q0K8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_2049</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017315.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2049"/>
    <dbReference type="EnsemblBacteria" id="ADD41744">
        <property type="protein sequence ID" value="ADD41744"/>
        <property type="gene ID" value="Snas_2049"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2049"/>
    <dbReference type="eggNOG" id="COG1108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028808_3_1_11"/>
    <dbReference type="OMA" id="ALMGDGI"/>
    <dbReference type="OrthoDB" id="1421296at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="283" mass="29134" checksum="0EC18D790C64A4D4" modified="2010-04-20" version="1">MEIFTYGFMLQALAAAMIVGVSAPTVGIYLVQKRMALIGDGLGHVALTGVALGFLTNTQPLWTTLLVTALGAVAVEVIRTRGRASGDVALALLFYGGIAGGVFITSLVSGKTNANLNEYLFGALLTVSDAEVWAIGILGCVVTFVMVVLRPWLAAICHDEEHARVAGLPVGALNLLVAVTTAVTVSVAMRVVGLLLISALLVVPVVTAQQFTRGFATTMYSAMGLGLLASGAGFVTAGVLEEVPPGAAIVLVAVALFIVVAVGRAIWLALRRRALAPSVASIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0M4</accession>
    <name>D3Q0M4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017331.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2066"/>
    <dbReference type="EnsemblBacteria" id="ADD41760">
        <property type="protein sequence ID" value="ADD41760"/>
        <property type="gene ID" value="Snas_2066"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2066"/>
    <dbReference type="eggNOG" id="ENOG502Z8GJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_326490_0_0_11"/>
    <dbReference type="OMA" id="WRVRLYR"/>
    <dbReference type="OrthoDB" id="268157at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="882" mass="96209" checksum="0D0ED1F47F083E88" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0W7</accession>
    <name>D3Q0W7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_4065</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18977"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.1.5.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019288.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4065"/>
    <dbReference type="EnsemblBacteria" id="ADD43717">
        <property type="protein sequence ID" value="ADD43717"/>
        <property type="gene ID" value="Snas_4065"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4065"/>
    <dbReference type="eggNOG" id="COG0578">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015740_5_1_11"/>
    <dbReference type="OMA" id="CIVNAAG"/>
    <dbReference type="OrthoDB" id="360065at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052591">
        <property type="term" value="F:sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="PTHR11985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00977">
        <property type="entry name" value="FAD_G3PDH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="8">
        <location>
            <begin position="25"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="DAO_C" evidence="9">
        <location>
            <begin position="402"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="544"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="567" mass="61885" checksum="65F4CFAAB3CEFC89" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1A1</accession>
    <name>D3Q1A1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD linked oxidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021252.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6057"/>
    <dbReference type="EnsemblBacteria" id="ADD45681">
        <property type="protein sequence ID" value="ADD45681"/>
        <property type="gene ID" value="Snas_6057"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6057"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_10_2_11"/>
    <dbReference type="OrthoDB" id="330793at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="34"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="451" mass="47633" checksum="C3DFA05EEE1ED464" modified="2010-04-20" version="1">MIDLARLRERFAGEVFSPASAGYEAVRVAANPRFDDVRPQLVLRCRSVADVVSALSFARDDDVHIVPRGGGHCFAGRSSTDGTVLDLAELDDIDVAAAGTATIGAGARLAQVYAALHRHGRTIPAGCGATVGIAGLTLGGGIGLLGRAHGLTCDRLVGATVVLADGRVVNCGPDRDPELFWALRGAGGGQFGVVTSLVFATIPEPMTIPFEARWTEAHIAEVIEAWQHWAPDAPDELTANLAVTAEPGRPVEAVLSGASLLSHSATTDLLNEFRARTGTSPAIAVGDALPYHRLKQTLAELDPQEPGLRIRSEFFAEPMRPPTIQALTGAIADGTGEPRRLGFTAMGGAYDRVAASATAFAHRDQRFLVEHLAAADSAWIDESWAIAHTDGSGRVYPNFPDPALDDWATAYHADNFPRLVAAKNRYDPGGLFTFPQSVPANGSVPPTPKHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1R7</accession>
    <name>D3Q1R7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0196"/>
    <dbReference type="EnsemblBacteria" id="ADD39915">
        <property type="protein sequence ID" value="ADD39915"/>
        <property type="gene ID" value="Snas_0196"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0196"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="WDSLGCA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTAD" evidence="2">
        <location>
            <begin position="129"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="967" mass="105437" checksum="3FD833AA2461A3A9" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q263</accession>
    <name>D3Q263_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2240"/>
    <dbReference type="EnsemblBacteria" id="ADD41930">
        <property type="protein sequence ID" value="ADD41930"/>
        <property type="gene ID" value="Snas_2240"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2240"/>
    <dbReference type="eggNOG" id="COG0662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132093_0_0_11"/>
    <dbReference type="OMA" id="LCAWRGE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="37"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="124" mass="13413" checksum="4B82719EB12E5301" modified="2010-04-20" version="1">MPVMPASEAKVHEFDGSRWKAFVAPSKGSTELCAWRAEIPADAKTSPHRVNKEEVLLVLKGRLRMVHEGCDLIAESGDAIVVPPDTDVHITNVGDETAETWVTTSVGFAGTMPDGSVFTPPWVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q278</accession>
    <name>D3Q278_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycoside hydrolase family 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_4160</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4160"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43811">
        <property type="protein sequence ID" value="ADD43811"/>
        <property type="gene ID" value="Snas_4160"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4160"/>
    <dbReference type="eggNOG" id="COG3325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002833_14_4_11"/>
    <dbReference type="OMA" id="WEWPGAE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
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        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="SSF54556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048576" evidence="6">
        <location>
            <begin position="31"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="8">
        <location>
            <begin position="28"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="144"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="239"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="9">
        <location>
            <begin position="330"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="212"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD43811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="762" mass="80980" checksum="EA4C0B045CBF4BE5" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q283</accession>
    <name>D3Q283_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase PA-phosphatase related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4165"/>
    <dbReference type="EnsemblBacteria" id="ADD43816">
        <property type="protein sequence ID" value="ADD43816"/>
        <property type="gene ID" value="Snas_4165"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4165"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078789_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
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        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="116"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="307" mass="34385" checksum="AD98F99D64C8897A" modified="2010-04-20" version="1">MVQIRKWAHNTFWNSAAFAERTWPIKQDKWEPFGKAPKSWLPDILCAVGFVVITVMLLFQSPLTELDEAVRVFLHDNRMLWLDWVTRVLNHLGAGRVVAPMVLLVTLWCAVRYKSIRPLLMYTVAYLPLGIIFLMKHGFGRMLSQPGAKIGVIEQYPEKLELFTYIGAGTAYPSGHAANTIVWFGLAVLVIGAALPRWLRIFLLVGPPVVVGFTQTYMGLHWLTDAPAGYLLGILIIRSVRRVSWGTVPLGPLRRFEPASPEIIVSATVTVGGLLLCATKYLPAMILGVIICILGALWMLKVLRQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2E2</accession>
    <name>D3Q2E2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019446.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4226"/>
    <dbReference type="EnsemblBacteria" id="ADD43875">
        <property type="protein sequence ID" value="ADD43875"/>
        <property type="gene ID" value="Snas_4226"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4226"/>
    <dbReference type="HOGENOM" id="CLU_1255331_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="220" mass="22481" checksum="23A89EF10126C688" modified="2010-04-20" version="1">MPTTPGTTPEDAATGTGATGEESGTLAEVPPEPPAAASGTTPAATGTTAGDSGTSGDAPPPPAPAPADSPPEAPPWERTGQPFDAETAWKLITNLRAEVARGKAGAPTGPGGTDELAQRVTSLEQQLAEERAAARARIGEQHQMPEPVVALLGDGDGKTLAARAQALIDWAHTLNRPAPSRGARRRPVAELRSGTTPEQPPEDTDPARLAAQVAARRPHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2H3</accession>
    <name>D3Q2H3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4257"/>
    <dbReference type="EnsemblBacteria" id="ADD43906">
        <property type="protein sequence ID" value="ADD43906"/>
        <property type="gene ID" value="Snas_4257"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4257"/>
    <dbReference type="eggNOG" id="ENOG5033N0M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1097598_0_0_11"/>
    <dbReference type="OMA" id="ARPNTEH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="266" mass="28366" checksum="9B3035CF83BDE398" modified="2010-04-20" version="1">MGWFGSGVPQSVKRLRRRLRSARRWSVMAGIFGGASGVLVPLGGLSGWDAIWTALFGGSAVLAAFKWTDYRKLAKALPAENEQLAVYGTAALSAEAQNIAGAIAGKVRRGRMAVQYRNSAASHGWQRLEAAALAFDEIAPRLAGPAADTLVDVRESQRALRDLADQIRSVEKSVNITPPDRRGSLTETHGLMVERFETGVSAYEDLVGAAAQVVAEQGALDGVVSGEDPTMTRLNEATSKLSGLAEGIGQMREFHTGVQPRIPPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2K4</accession>
    <name>D3Q2K4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="15">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Snas_4288</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 15">
            <text>2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 15">
            <text>2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 14">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 16">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 16">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6 16">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 13">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="15"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019508.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4288"/>
    <dbReference type="EnsemblBacteria" id="ADD43937">
        <property type="protein sequence ID" value="ADD43937"/>
        <property type="gene ID" value="Snas_4288"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4288"/>
    <dbReference type="eggNOG" id="COG0115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031922_0_2_11"/>
    <dbReference type="OMA" id="LTEVFAC"/>
    <dbReference type="OrthoDB" id="1275805at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050048">
        <property type="term" value="F:L-leucine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="PTHR11825"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01123">
        <property type="entry name" value="ilvE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 15 17" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="11 14" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 15 17" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="12">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00005072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ADD43937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="365" mass="40139" checksum="F386002F7E84F746" modified="2010-04-20" version="1">MIGGDLPQFDIRPNPRPRSAAERAEILANPGFGLHFTDHMVTIQYTEGQGWHDPTVQAYGPIQMSPATAVLHYAQEIFEGMKAYHRADGKIGLFRADENARRFQRSAERMAMAQLPEEWFLASLQALIDVDKSWVPDDEDSSLYLRPFMFANEAFLGVRPAKEFLYCVIASPAGAYFKSGPKPVSLWVSQEYTRAAPGGTGAAKCGGNYATSLRPQSEAIENGCEQVVFLDAVHRKYIDELGGMNIFFVYEAEKKIVTPELGTILAGVTRDAVLTLGRDLGYRVEERQYSFEEWKADALSGSLSETFACGTAAVLTPVGTVRDHTGEFHASGGKAGELTMKLRQTLLDIQHGKAADPYGWTSVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2K7</accession>
    <name>D3Q2K7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase of anthranilate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021329.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6135"/>
    <dbReference type="MEROPS" id="C26.955"/>
    <dbReference type="EnsemblBacteria" id="ADD45758">
        <property type="protein sequence ID" value="ADD45758"/>
        <property type="gene ID" value="Snas_6135"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6135"/>
    <dbReference type="eggNOG" id="COG0512">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014340_1_2_11"/>
    <dbReference type="OMA" id="TEHGHAM"/>
    <dbReference type="OrthoDB" id="1561172at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="189" mass="20522" checksum="133887507CA2B9BB" modified="2010-04-20" version="1">MRIFVADCRDSFVYTIVDYLRGLGAEVVIRRADEFTADEVPLTGTDALLLSPGPGRPGEARTCHALLDRFAGRRPVLGVCLGHQVIAEHYGGTVSRADEPRHGETSRISHDEAGLFAGLPNPVTVTRYHSLIVDEPLPHDLAVTARAESGEIMALRHRELPVAGVQFHPEAILTEGGHHLLGNWLSLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2U9</accession>
    <name>D3Q2U9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-alanyl-D-alaninecarboxypeptidase/ D-alanyl-D-alanine-endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021421.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6229"/>
    <dbReference type="MEROPS" id="S13.004"/>
    <dbReference type="EnsemblBacteria" id="ADD45850">
        <property type="protein sequence ID" value="ADD45850"/>
        <property type="gene ID" value="Snas_6229"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6229"/>
    <dbReference type="eggNOG" id="COG2027">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017692_0_1_11"/>
    <dbReference type="OMA" id="HSDNTLA"/>
    <dbReference type="OrthoDB" id="720131at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000667">
        <property type="entry name" value="Peptidase_S13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30023">
        <property type="entry name" value="PTHR30023"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02113">
        <property type="entry name" value="Peptidase_S13"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00922">
        <property type="entry name" value="DADACBPTASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00666">
        <property type="entry name" value="PBP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048821" evidence="2">
        <location>
            <begin position="23"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="436" mass="43933" checksum="4D2187AC87D82136" modified="2010-04-20" version="1">MVSVLVAAGVVFVTVDTRPASALLSFPEMAPPKAPGAPEGLDADAPAVDADALAAELDPLINGGSLKGKTTATVLDGFTGESLYASQGDKAATPASSTKVATAAAALTARGPAYRIPTKVVEGESEGEVVLVAGGDVMLSKDGDGFFRGAASLADLAEQVKKAMGDKQITKLVVDMSIFADDPVAPGVPAADVASGYTAKLEPIMLDGGRSGPDPGSRAARHDDPSAAVTDALSELLGGVEVAEGTAKKDAAELGVVHSPTMQRLAEFALVTSDNLLADALARQTALAKDKDASFAGGVEATIDVLSDMDVPMDGVELSDNSGLSLDNRLTSDALAAVVYQAANGKHTAASGILAGFPVSGYSGALDDRYDDADVVGKVHAKTGTLTTVNSLTGMTVTKEGRLLAFSIIFNGKGNGPDVEAAIDEVASTLSRCGCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Y8</accession>
    <name>D3Q2Y8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Helicase c2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0239</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0239"/>
    <dbReference type="EnsemblBacteria" id="ADD39958">
        <property type="protein sequence ID" value="ADD39958"/>
        <property type="gene ID" value="Snas_0239"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0239"/>
    <dbReference type="eggNOG" id="COG1199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012117_2_0_11"/>
    <dbReference type="OMA" id="VVTNHAM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="PTHR11472"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="12"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="34"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD39958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="664" mass="70556" checksum="1A466C81C17E561F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q342</accession>
    <name>D3Q342_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0294</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015583.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0294"/>
    <dbReference type="EnsemblBacteria" id="ADD40012">
        <property type="protein sequence ID" value="ADD40012"/>
        <property type="gene ID" value="Snas_0294"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0294"/>
    <dbReference type="eggNOG" id="COG0652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_16_3_11"/>
    <dbReference type="OMA" id="ELYNDHA"/>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="170" mass="18043" checksum="F5D0B9D445E9DD6E" modified="2010-04-20" version="1">MTTATLHTNVGDIVIQLFDNHAPKTVANFVGLAEGTQEYTDPTTGSSGSGPYYDGTVFHRVIDGFMIQGGDPTGTGRGGPGYQFDDEIHPDLAYVKPYLLGMANAGKGTNGSQFFITTGPQPHLTGKHTIFGEVSDPASQKIVDTIGSTQTGAGDRPVNEIRIERVTITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3K5</accession>
    <name>D3Q3K5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_2360</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017617.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2360"/>
    <dbReference type="EnsemblBacteria" id="ADD42046">
        <property type="protein sequence ID" value="ADD42046"/>
        <property type="gene ID" value="Snas_2360"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2360"/>
    <dbReference type="eggNOG" id="COG1104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_0_0_11"/>
    <dbReference type="OMA" id="KGLYWAR"/>
    <dbReference type="OrthoDB" id="839689at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="8">
        <location>
            <begin position="3"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="387" mass="40410" checksum="8ACB39EC8BE1ECA8" modified="2010-04-20" version="1">MTYLDHAATTPMLPRARDAYLEAATQIGNPSSLHASGRTARRRVEEARELIADRLGAAPSEVVFTGGGTESDNLALKGQFWARRDAEPSRTRILAAETEHHAVVDVVRWLVEHEGAEAIWLPVDHTGRLAEERVAEALEQHGDEIALATVMWANNEVGTVQPVVEIAAAAAAAGVPCHSDAVQAVAQLPVSFADTELTSLALTGHKLGGPAGVGALLLRRDAVCVPLLHGGGQEREVRSGTVDVAGIVSFAAAVDVSVTGQEETAKHLTKLRDDLIARVRAAIPDAVLNGDPDNRLPGNAHFSFPGCEGDALLMLLDAAGVECATGSACSAGVAQPSHVLLAMGHDERLARSSLRFTLGHTSTTADVDALIAALPGAVERARTAGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3P3</accession>
    <name>D3Q3P3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019531.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4313"/>
    <dbReference type="EnsemblBacteria" id="ADD43960">
        <property type="protein sequence ID" value="ADD43960"/>
        <property type="gene ID" value="Snas_4313"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4313"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_1_11"/>
    <dbReference type="OMA" id="SANISHW"/>
    <dbReference type="OrthoDB" id="816674at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="400" mass="43749" checksum="563018A04943DDA1" modified="2010-04-20" version="1">MTGRSTPLTALPMTRAEGRPFDPPPLLARLRDEAPLRRLTYADGHQGWLATGHEEVRTLLGDNRISPRPDLIHLPFELEGITTLPAPAPGAVNQLDGPDHARLRQPLVGWFTVRRMRQLTHQVETLVADLLDDMADRGPDVDLVDEFAYPLPVTVVCDLLGVPESDRATFRDLVTTSGRSDLPIPDRLAANEQLGGYVGELVAAKRARPADDIISALTETDLDDTDVVGLSAFLISAGFDTTANMLALGTMALLEHPSQLAAWRADPGITNTAVEELMRYLSIVHTTVHSAVDDIEIAGQTIKAGDSVTLSFMAANRDPRKFPDPDRLDLRRNATGHLGFTHGAHACLGQQLARVEMRAAFPALLRRFPNLRLNIAIEDVPLRDPLILVYGLDRLPVTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3P6</accession>
    <name>D3Q3P6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4316</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4316"/>
    <dbReference type="EnsemblBacteria" id="ADD43963">
        <property type="protein sequence ID" value="ADD43963"/>
        <property type="gene ID" value="Snas_4316"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4316"/>
    <dbReference type="HOGENOM" id="CLU_3030239_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="55" mass="6320" checksum="BA3F9F4FA18D3D0A" modified="2010-04-20" version="1">MEKATLEQQDHEPYPVDKTGERAWCRTCTRYYQAVIVYPCSHARKRVGADSEASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3P8</accession>
    <name>D3Q3P8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4318</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019536.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4318"/>
    <dbReference type="EnsemblBacteria" id="ADD43965">
        <property type="protein sequence ID" value="ADD43965"/>
        <property type="gene ID" value="Snas_4318"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4318"/>
    <dbReference type="eggNOG" id="ENOG5031XGV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131550_0_1_11"/>
    <dbReference type="OrthoDB" id="1996962at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="2">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="DUF397" evidence="2">
        <location>
            <begin position="29"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="85" mass="9266" checksum="D1971DFBD1F42CE9" modified="2010-04-20" version="1">MTHVTGPWRKSSRSGQSNGTACVEARAVATWRKSSRSGQSNGTNCVEARLVEATFQLRDSKLGDGSPTLAMTNSDWRGLLTLIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3R5</accession>
    <name>D3Q3R5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zf-CGNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019553.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4335"/>
    <dbReference type="EnsemblBacteria" id="ADD43982">
        <property type="protein sequence ID" value="ADD43982"/>
        <property type="gene ID" value="Snas_4335"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4335"/>
    <dbReference type="eggNOG" id="COG5516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087298_3_1_11"/>
    <dbReference type="OMA" id="ETHECSW"/>
    <dbReference type="OrthoDB" id="1478254at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010852">
        <property type="entry name" value="ABATE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023286">
        <property type="entry name" value="ABATE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021005">
        <property type="entry name" value="Znf_CGNR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35525">
        <property type="entry name" value="PTHR35525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07336">
        <property type="entry name" value="ABATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11706">
        <property type="entry name" value="zf-CGNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160904">
        <property type="entry name" value="SSF160904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-CGNR" evidence="1">
        <location>
            <begin position="134"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="178" mass="19751" checksum="E172C4FC1C1A8EED" modified="2010-04-20" version="1">MTYEWVWDGGRPCLDFINTRRDRYASGHEMLAEPSHLHDWLRRAGLVEPDTPVTPSELDDARDLREQLDRVLGTGGSPSPADIDAVNTWARRAPIPQLTPDGGVTPSHVGVEAALGVIAADAIDLLAGHTRPTLRVCASDTCGLRFLDRSPARNRQWCSMSRCGNREKARKHYGRKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3W4</accession>
    <name>D3Q3W4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Transcriptional regulator WhiB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">whiB</name>
        <name evidence="14" type="ordered locus">Snas_4384</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="12">The Fe-S cluster can be nitrosylated by nitric oxide (NO).</text>
    </comment>
    <comment type="PTM">
        <text evidence="12">Upon Fe-S cluster removal intramolecular disulfide bonds are formed.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the WhiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4384"/>
    <dbReference type="EnsemblBacteria" id="ADD44031">
        <property type="protein sequence ID" value="ADD44031"/>
        <property type="gene ID" value="Snas_4384"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4384"/>
    <dbReference type="eggNOG" id="ENOG5032RVG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106245_3_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035731">
        <property type="term" value="F:dinitrosyl-iron complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01479">
        <property type="entry name" value="WhiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034768">
        <property type="entry name" value="4FE4S_WBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000637">
        <property type="entry name" value="HMGI/Y_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003482">
        <property type="entry name" value="Whib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38839">
        <property type="entry name" value="PTHR38839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02467">
        <property type="entry name" value="Whib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51674">
        <property type="entry name" value="4FE4S_WBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00354">
        <property type="entry name" value="HMGI_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0408">Iron</keyword>
    <keyword evidence="7 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 12" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="4Fe-4S Wbl-type" evidence="13">
        <location>
            <begin position="39"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ADD44031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="135" mass="14940" checksum="570192A8F7FB4D69" modified="2010-04-20" version="1">MTHYPRNQMTITTEREVTEVMTLGPGLREQAINKGRDLACREYDADLWFADTPTELEFAKSLCADCPVKVECLAGAMDRQEPWGVWGGEIFEAGAIVARKRPRGRPRKDAAEQEAAAQAALAERTKDVMATLEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q439</accession>
    <name>D3Q439_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Radical SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_6305</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6305"/>
    <dbReference type="EnsemblBacteria" id="ADD45924">
        <property type="protein sequence ID" value="ADD45924"/>
        <property type="gene ID" value="Snas_6305"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6305"/>
    <dbReference type="eggNOG" id="COG1180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044176_1_0_11"/>
    <dbReference type="OMA" id="YHFYPGS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027596">
        <property type="entry name" value="AmmeMemoSam_rS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01101">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04337">
        <property type="entry name" value="AmmeMemoSam_rS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="83"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="356"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD45924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="388" mass="42697" checksum="F2D0A8D33155E4A7" modified="2010-04-20" version="1">MPAATGADALSLADPYTIGTKYWHELDDGRIQCDVCPRNCRLREGQRGLCFVRGRIGDQIVLASYGRSSGFCVDPVEKKPLNHFLPGTPVLSFGTAGCNLACRFCQNWDISKSREIDTLSGEAAPDTLAQAASKLECSSIAFTYNDPTIFLEYAVDAAQACKELGIKTIAVSAGYINAEPRAEFYSHMDAANIDLKAFTEDFYQKIAFSKLGTVLDTLKYLRHETDVWLEITTLLIPGYNDSNSELAEMCAWIAEHLGDEVPLHFSAFHPDFKMRDVPATPPATLSRARRIAIDHGLKYVYTGNVHDTDGGTTHCGGCGKPVVVRDWYVLKEYRIDGTGHCEHCGARIPGVYSGPAGTWGPKRRPVRLGTPRVRTGDHDRRNATATKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4A9</accession>
    <name>D3Q4A9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6378</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021565.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6378"/>
    <dbReference type="EnsemblBacteria" id="ADD45994">
        <property type="protein sequence ID" value="ADD45994"/>
        <property type="gene ID" value="Snas_6378"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6378"/>
    <dbReference type="eggNOG" id="COG4289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028269_0_0_11"/>
    <dbReference type="OMA" id="WVIHPFL"/>
    <dbReference type="OrthoDB" id="205789at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016624">
        <property type="entry name" value="UCP014753"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35339">
        <property type="entry name" value="PTHR35339"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10022">
        <property type="entry name" value="DUF2264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="626" mass="67366" checksum="757D8DAD9273EFD2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4K8</accession>
    <name>D3Q4K8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015739.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0453"/>
    <dbReference type="EnsemblBacteria" id="ADD40168">
        <property type="protein sequence ID" value="ADD40168"/>
        <property type="gene ID" value="Snas_0453"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0453"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_933101_0_0_11"/>
    <dbReference type="OMA" id="IHNIGYR"/>
    <dbReference type="OrthoDB" id="2042171at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="297" mass="32073" checksum="BDD85EAD01048551" modified="2010-04-20" version="1">MSSPVNGLPNSGVIHNIGYRRYEGARLDSFNIAKALYSQTLRGSYGIGRGIVAKLFPWFLVGAILLPAFIIMAIMNFQKQPILEISDYTMFVQAVPALFLAVQAPHAVSRDLRFGVMPLYLSRPLTYRGYVHAKIAGVWTGLFALMAAPLLILYLANLLIKLPFGDSTLDLGASLFGCALLAALFTMLGLLIASVTPRRGLGVAAIIAVLMGSFGVASFAQTFLMEFGSTSSAHMAGMLSPVTLYQGVQAFLFDTKQTLVNIRPDLAIGGVLTLVTIAILVLSYLLLMARYRKVSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4L6</accession>
    <name>D3Q4L6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD40176">
        <property type="protein sequence ID" value="ADD40176"/>
        <property type="gene ID" value="Snas_0461"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0461"/>
    <dbReference type="eggNOG" id="ENOG5031X9V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1123967_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="247" mass="27813" checksum="A92EA72998382F58" modified="2010-04-20" version="1">MRPTILSSILSLIVGGLVFPDLRDIAEWAARRLVKWAAPKWTDDETEAEALYEDWQAVIEDRPGAILKLVTATGFCVSAATRSYGRVVKSDYREAFKDQPSFATGLLRLWKIRGDRMQREVTIVIIKRALGNQLTYRQRFTNAVLVLGFLGSFFGWIWFCIGHNRVDNQTVSNGTTIVAATYLVLWWLLRRRRRKKFSQVSDPAVALTCSSEAVFTMKDPRSGREVMVTIREIPETTPGGLSAGNPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4N8</accession>
    <name>D3Q4N8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vault protein inter-alpha-trypsin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2383</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2383"/>
    <dbReference type="EnsemblBacteria" id="ADD42068">
        <property type="protein sequence ID" value="ADD42068"/>
        <property type="gene ID" value="Snas_2383"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2383"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011139_0_0_11"/>
    <dbReference type="OMA" id="FNVIRFD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013694">
        <property type="entry name" value="VIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08487">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00609">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51468">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VIT" evidence="3">
        <location>
            <begin position="20"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="305"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="664"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="811"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="831" mass="89202" checksum="F4B9DF14A3293572" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4V9</accession>
    <name>D3Q4V9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2456</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2456"/>
    <dbReference type="EnsemblBacteria" id="ADD42139">
        <property type="protein sequence ID" value="ADD42139"/>
        <property type="gene ID" value="Snas_2456"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2456"/>
    <dbReference type="HOGENOM" id="CLU_220073_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="37" mass="4126" checksum="5CE1A02AD0E97775" modified="2010-04-20" version="1">MEKKKSKAKLESMLGAVERRVPATKPAKSSCTRIYCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4W8</accession>
    <name>D3Q4W8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2465</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017719.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2465"/>
    <dbReference type="EnsemblBacteria" id="ADD42148">
        <property type="protein sequence ID" value="ADD42148"/>
        <property type="gene ID" value="Snas_2465"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2465"/>
    <dbReference type="eggNOG" id="COG0488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_0_11"/>
    <dbReference type="OMA" id="AQADKMR"/>
    <dbReference type="OrthoDB" id="1112046at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="331"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="363"/>
            <end position="370"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="541" mass="58516" checksum="45BD3859B5A2A19C" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4X9</accession>
    <name>D3Q4X9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2476"/>
    <dbReference type="EnsemblBacteria" id="ADD42159">
        <property type="protein sequence ID" value="ADD42159"/>
        <property type="gene ID" value="Snas_2476"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2476"/>
    <dbReference type="eggNOG" id="ENOG502ZAMQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034353_1_1_11"/>
    <dbReference type="OMA" id="HKYRHVM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048235" evidence="1">
        <location>
            <begin position="37"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="390" mass="41572" checksum="2B06726E3058C289" modified="2010-04-20" version="1">MNTPLRNAARFLIRALTLTVVATGTVIAFTATSASAAPNPANFALNRADTNSGLLSGLDAALPNKTVPNVLDSANRTGTACTAPVQHRAASFCWQSGDNTVTYWIPQGLSTSADATGGAYQGRNALLSAWYDNTTGTGDRGARISFVDMANTTTPKYRHVLLVEPTGTASAPSYKAIDTHAGGLAWYGDKLYVCDTFGGMRVFDMKHILAANNMTDTLIGRQSDGSYASRGYAYVMPQVAKYNPTTSGGEAALRFSQVSVDRTSAKHSLVVSEWDAVGDTTRIVRFDVDANGNATPDGDGVARADWAYQVGFRSMQGAAAVNGIYYVHRNSTSGLGGMIKWTPGSTAKVMDDTLPRGPEDVSYWIGKDQLWGQTEHAGSRYVFASRVSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q523</accession>
    <name>D3Q523_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome segregation and condensation protein ScpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4427</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4427"/>
    <dbReference type="EnsemblBacteria" id="ADD44072">
        <property type="protein sequence ID" value="ADD44072"/>
        <property type="gene ID" value="Snas_4427"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4427"/>
    <dbReference type="eggNOG" id="COG1354">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038686_1_0_11"/>
    <dbReference type="OMA" id="YLVMAAM"/>
    <dbReference type="OrthoDB" id="959677at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003768">
        <property type="entry name" value="ScpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33969">
        <property type="entry name" value="PTHR33969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02616">
        <property type="entry name" value="SMC_ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="33707" checksum="4786C3DCE0F0F93C" modified="2010-04-20" version="1">MNSERPGEPDSAVATLPDPQADGAGDAELPAETDAKGFQVRLDNFTGPFDLLLQLIGKHKLDVTEVALHQVTDDFISYTRSLGDDWDLNETSEFLLIAATLLDLKAARLLPSADVEDEEDLALLEARDLLFARLLQYKAFKDAAGHIDKLTEGAALRFPRTAGLESRYAEALPELVLNIGADQLAAMAAAALKPKPPPTVGVDHVHMVRVSVREHAIILQRRLKRVITSTFRALTSDCESTLEVVARFLALLELYREGMVGFDQVQALGELTVRWVAAEDSSDIEVDEYVGAPAEATDATGEAAEAEESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5B4</accession>
    <name>D3Q5B4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="5">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4518</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019734.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4518"/>
    <dbReference type="EnsemblBacteria" id="ADD44163">
        <property type="protein sequence ID" value="ADD44163"/>
        <property type="gene ID" value="Snas_4518"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4518"/>
    <dbReference type="eggNOG" id="COG0722">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030903_0_1_11"/>
    <dbReference type="OMA" id="NIRDGRQ"/>
    <dbReference type="OrthoDB" id="853329at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DHAP_synth_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PTHR21225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="6">
        <location>
            <begin position="32"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="347" mass="36558" checksum="65AC7463C85C9DAD" modified="2010-04-20" version="1">MSVLSGPASLRATVTTDPKLAAEVELSRGTIRAILDGADQRLLILVGPCSVHDPRELRRYATGLAEVAAAHAEDVYLVVRAYTEKPRTRHGWPGLLLDPGLDGGYAVPAGLAETRRVLTEINTLGLPVACEFVEPQLAPYLSDLVSWAGIGARTVESPPHRRLASHLPMPVGFKNRVDGAITPAVDAIAVASRPQPVITVDDHGRCAWTVSDGNPDTHLVLRGGETGTNYAAHQVNHALGLLADVQSHPKLIVDCSHGNSGKDHNRQPVVAEAIAAQIAAGQTGIAGVMLESYLSPGAQSLDGTLRPGVSVTDACLGFADTAEVIENLALAAKQRRAGRTTELVNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q657</accession>
    <name>D3Q657_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable allantoicase</fullName>
            <ecNumber evidence="3">3.5.3.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Allantoate amidinohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">alc</name>
        <name evidence="5" type="ordered locus">Snas_2551</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>allantoate + H2O = (S)-ureidoglycolate + urea</text>
            <dbReference type="Rhea" id="RHEA:11016"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
            <dbReference type="ChEBI" id="CHEBI:57296"/>
            <dbReference type="EC" id="3.5.3.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nitrogen metabolism; (S)-allantoin degradation; (S)-ureidoglycolate from allantoate (aminidohydrolase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the allantoicase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.4" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017803.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2551"/>
    <dbReference type="EnsemblBacteria" id="ADD42232">
        <property type="protein sequence ID" value="ADD42232"/>
        <property type="gene ID" value="Snas_2551"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2551"/>
    <dbReference type="eggNOG" id="COG4266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038797_1_0_11"/>
    <dbReference type="OMA" id="MDDGWET"/>
    <dbReference type="OrthoDB" id="651058at2"/>
    <dbReference type="UniPathway" id="UPA00395">
        <property type="reaction ID" value="UER00654"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004037">
        <property type="term" value="F:allantoicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00813">
        <property type="entry name" value="Allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005164">
        <property type="entry name" value="Allantoicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015908">
        <property type="entry name" value="Allantoicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12045">
        <property type="entry name" value="PTHR12045"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03561">
        <property type="entry name" value="Allantoicase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016516">
        <property type="entry name" value="Allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02961">
        <property type="entry name" value="allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Allantoicase" evidence="4">
        <location>
            <begin position="15"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Allantoicase" evidence="4">
        <location>
            <begin position="184"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="340" mass="37100" checksum="2E5611ABCCC96EC2" modified="2010-04-20" version="1">MQFTDLPDLAVRSLGGAVLAANDESFAEKECLVRDPEPVYTPHDFGNKGQIYDGWETRRRREPGHDWALIRLGVPGLVHGVVVDTAFFKGNYPPEVSVEGCTLGGYPGPAELAEADWRELVPRSQASGHTKNHYKVDSPRHVTHVRLNMHPDGGIARLRVHGEPVPDPALFTRLPLDLAALVNGGGVVAASDSFYSRPWGAIMPGNASSQADGWETGRRRDDGNDWLTVKLAGRGVIAVAELDTTHLKFNAPGAAALRGFDAAAGADMDDESAWFDLLGRTRLQPDTPHRFAVEDARPATHVRLDIYPDGGMARLRLFGELTAEALRDIERRYLTLTSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q690</accession>
    <name>D3Q690_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2585"/>
    <dbReference type="EnsemblBacteria" id="ADD42265">
        <property type="protein sequence ID" value="ADD42265"/>
        <property type="gene ID" value="Snas_2585"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2585"/>
    <dbReference type="HOGENOM" id="CLU_1618023_0_0_11"/>
    <dbReference type="OMA" id="KKFHTVR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019933">
        <property type="entry name" value="DivIVA_domain"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03544">
        <property type="entry name" value="DivI1A_domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="164" mass="18049" checksum="A170FD1ED0507F04" modified="2010-04-20" version="1">MNTPFQPPTFTIVMRGYDVERVNQLVARIAAAHDNPDAITAAELRDVKLPVVARGFKTKQVDQFLASTVTALAASGQPQRPTVAAVPSLSTRPRGDRFPKRFGNAYRPGDVDAFVERVSSTLNTTLTSHETRSVRFGTGFRGYAVDPVDAWLDQVQTYLLSRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6K3</accession>
    <name>D3Q6K3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4602</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019817.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4602"/>
    <dbReference type="EnsemblBacteria" id="ADD44246">
        <property type="protein sequence ID" value="ADD44246"/>
        <property type="gene ID" value="Snas_4602"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4602"/>
    <dbReference type="eggNOG" id="COG1633">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082377_0_0_11"/>
    <dbReference type="OMA" id="WARRLMG"/>
    <dbReference type="OrthoDB" id="1414501at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="220" mass="23794" checksum="4BC3B880D1A58E85" modified="2010-04-20" version="1">MSSQATKPSTASIIDLLGMLAYGELVAFDRIAADAKLAPDLRRRASLSAMAAAEINNYQRLVARITELGGDPEAAMTPFVEVIDAFHDSTAPRDWLEGLVKVYVGDSIADDFFREMAALLPPTDRDLVLDVLHNNANAEFAISEINEALGRDPKLAGKLALWARRLVGEALSQAQRVAAEHDSLTEIVIEGTGDLAKVGELIKRIMQAHSNRMTAIGLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6Q9</accession>
    <name>D3Q6Q9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Bilirubin oxidase</fullName>
            <ecNumber evidence="6">1.3.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4659</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.3.5" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019873.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4659"/>
    <dbReference type="EnsemblBacteria" id="ADD44302">
        <property type="protein sequence ID" value="ADD44302"/>
        <property type="gene ID" value="Snas_4659"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4659"/>
    <dbReference type="eggNOG" id="COG2132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009100_2_2_11"/>
    <dbReference type="OMA" id="PYSGRYV"/>
    <dbReference type="OrthoDB" id="971126at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047705">
        <property type="term" value="F:bilirubin oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048909" evidence="3">
        <location>
            <begin position="28"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="73"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="167"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="4">
        <location>
            <begin position="407"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="515" mass="56935" checksum="B28B70E01C8EBBB0" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6T5</accession>
    <name>D3Q6T5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_0620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015905.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0620"/>
    <dbReference type="EnsemblBacteria" id="ADD40334">
        <property type="protein sequence ID" value="ADD40334"/>
        <property type="gene ID" value="Snas_0620"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0620"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="VACWLVE"/>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="9"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="348" mass="38530" checksum="EDEC1C52A0FDDE5F" modified="2010-04-20" version="1">MNDEPILSVRDLEISYRTGKRTEVTAASDINFDLYPGESMALVGESGCGKTTLGLGLLKLLPRLGRVPRGTVTYRRKDGSRSDIMKLGKEELRRFRWSEAAMVFQGAMNAFNPVQRIADHFEDTLRDHANGQKRWSTADIKRRSEELLDLVRLEPDRVLRSYPHELSGGMKQRTLIALALALEPQLLVLDEPTTALDLLTQRSIVEQLHELRERLGFSMIFITHDLGLAAELADRVSTMYAGRIIESGTAEDIFYNPRHPYTAGLIKAVLPVAGDLPELESIPGTPPNLANLPPGCAFAPRCGYATSECSDEIPALTRIEGSNGNPPHTAACLHSDQVEFSRQVVSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6X2</accession>
    <name>D3Q6X2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylmalonate-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0658</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015942.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0658"/>
    <dbReference type="EnsemblBacteria" id="ADD40371">
        <property type="protein sequence ID" value="ADD40371"/>
        <property type="gene ID" value="Snas_0658"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0658"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_10_11"/>
    <dbReference type="OMA" id="NWTLRQP"/>
    <dbReference type="OrthoDB" id="490746at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="PTHR43866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="16"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="496" mass="52893" checksum="F974A87055826334" modified="2010-04-20" version="1">MTTIQHWIDGTATAADSTRTAPVWNPATGRQQAEVLLAEADAVDRAVAAARRAFETWGEVSLSARSKVMFALRQLLERHEDELARIICAEHGKAIDDARGEIVRGREVVEFACGIAEVLKGSFSNEVSSGVDLHSFRQPLGVCAGITPFNFPIMVPMWMHPVAIATGNTFVLKPSERDPSASNFVAQLYADAGLPDGVFNVVHGDKTAVDAILDHPDVAAVSFVGSTPIARYVHERAQSAGKRVQALGGAKNHAVVMPDADLGFAADQLTAAAFGSAGQRCMAVSVAVTVGDAADALVPVLRDKASGLNVGPGSEPGVDMGPVVTSQARDRIAGYVASGVKQGAEPVLDGREFRRDGDGFFIGPTVLDRVTSDMDVYRDEVFGPVLSVVRAETVEAAIDLINANPYGNGTAIFTSDGAVARRFEREVRVGMVGVNVPIPVPMSYYSFGGWKDSLFGETHIHGPEGVRFYTRLKVVTSRWPSQPRQVASRLHFPTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6X7</accession>
    <name>D3Q6X7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0663</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0663"/>
    <dbReference type="EnsemblBacteria" id="ADD40376">
        <property type="protein sequence ID" value="ADD40376"/>
        <property type="gene ID" value="Snas_0663"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0663"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="NDRCATG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="34862" checksum="E560B865A0131454" modified="2010-04-20" version="1">MSDVAARVGVSRALVSLVFRNAPGASLETRERVFRAAAELGYRPDLAARLLARGRSRVLGVLFTVRNPFHVDVVETIYPAAEELGYDIVLSAHVPSRDENQAIEALIGHRSEALILLGPIIPARDVAELGRRVPTVVVGRKVSRAPVDIVTTRDRPGVGEVVDYLIGLGHRDIVHVDGGSGPGSAERRRAYRDFMRKRGLAERVRVIGGDQTEESGAAAARTLLAEPRLPTAVFAGNDLCAIGLLDVFTRAGVSVPEDVSIVGYDDSHIAGLSHIDLTTVRQDVGQLAELAVRAADAQLSGSREAGVELLLDSRMVVRGTTAPPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q714</accession>
    <name>D3Q714_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015984.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0700"/>
    <dbReference type="EnsemblBacteria" id="ADD40413">
        <property type="protein sequence ID" value="ADD40413"/>
        <property type="gene ID" value="Snas_0700"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0700"/>
    <dbReference type="eggNOG" id="ENOG5034977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2791963_0_0_11"/>
    <dbReference type="OrthoDB" id="1663384at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="68" mass="7542" checksum="3283DBDC89A2899E" modified="2010-04-20" version="1">MNEIRDWQVSVALPIEASGYSEAVAQFWEYVRTLGPEELPAFVAPSGHELDMKAYVAGAETDLDPEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q784</accession>
    <name>D3Q784_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2678</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017926.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2678"/>
    <dbReference type="ESTHER" id="stanl-d3q784">
        <property type="family name" value="Duf_1023"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42355">
        <property type="protein sequence ID" value="ADD42355"/>
        <property type="gene ID" value="Snas_2678"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2678"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4099">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025057_2_1_11"/>
    <dbReference type="OMA" id="TWINTAR"/>
    <dbReference type="OrthoDB" id="2018813at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010427">
        <property type="entry name" value="DUF1023"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06259">
        <property type="entry name" value="Abhydrolase_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="507" mass="52812" checksum="E3691F772831F469" modified="2010-04-20" version="1">MVNYSQLLNMDTSKLSTAATTSGNLSKALTERAGEVGGKADIPAGMWAGLDAGLASSLISDQQSPLFDASDAFKRGQATLDDLVDGLQAAKERLADAHDLVAGTEVTIGPDGTVTTPPADNPTMANQNAFLARQAAEIIDDALRMANEADDKASAAVGEIDPASKKDIPNGKGDSAEDVKKWWDSLSKAEQDAYIKKFPKEIGNLDGIPAEARHEANMDSLRQDAKGGDNKFAKMLLDRIEDSRDGAKGDEIYLLGYEPGKGSDGKAIAAIGNPDTADHTAVNVPGTGTDLGNVAGGGLLANAADLRDQAMQEGNGSVSSIVWMGYDAPQGYVEAYDEGRALNGAGDLRDFTRGLDATNQGGDGHTTVIGHSYGSTVAGSADSRGMKVDDLVAVGSPGIGFEPDSKVDPPLPGPGGYLNSDRPSIENVDELNTDPNHVWAGASAGDPISYMSIHGANPAESDFGGERFATDGAGGHSEYYKEGTESLRNLGRIVAGEYDEVEHVDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q792</accession>
    <name>D3Q792_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017934.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2686"/>
    <dbReference type="EnsemblBacteria" id="ADD42363">
        <property type="protein sequence ID" value="ADD42363"/>
        <property type="gene ID" value="Snas_2686"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2686"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_0_2_11"/>
    <dbReference type="OMA" id="HGAHRCI"/>
    <dbReference type="OrthoDB" id="816674at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="387" mass="42447" checksum="CFF8DD7485830018" modified="2010-04-20" version="1">MSLARPEILVDPYPHYAKLRENTPVFFYEPLNSWMFTKYADCVAVLKDSARFAADWRRVGEQVPPRAINMLTLDPPEHTGVRRLFLETLRAQDNAKIEAQIAARTTELLDSLQDRESFDFLTEFAEPLALNTTADYLGVEPPEAEWTSRVGRIVAAGMDAGLWPERGAQLRDAHEELADLVDGWMADLPKTGILGELRARLDGTDVAPDVLANTVRGLLFSGFSSGGKLLASAAVTVFHERAAALPDFVAADPVRATDELVRYAGPIQAVARACITDTTIGDTQVKAEQAVTLLLGAANRDPDRFADPESVHLDRHPNPHLGFGRGPKSCLGSPFTAILLRVVMRMLSQRFPEAHATGEPSYLPNLTLRSLDRFPVSLRAESQAGVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7B0</accession>
    <name>D3Q7B0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42381">
        <property type="protein sequence ID" value="ADD42381"/>
        <property type="gene ID" value="Snas_2705"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2705"/>
    <dbReference type="HOGENOM" id="CLU_2511084_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="85" mass="9232" checksum="17E7D530FBF09862" modified="2010-04-20" version="1">MPQHDGCEAIGTVLNGSYKTRWHTKRAGAMWVLGSLTGFSTSMAIGAASVIAAVVALGFGTATVIVYRIERKQRRLRALTWHLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7B2</accession>
    <name>D3Q7B2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017954.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2707"/>
    <dbReference type="EnsemblBacteria" id="ADD42383">
        <property type="protein sequence ID" value="ADD42383"/>
        <property type="gene ID" value="Snas_2707"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2707"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_1_2_11"/>
    <dbReference type="OMA" id="PGYRNSG"/>
    <dbReference type="OrthoDB" id="1920912at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="4"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="192" mass="21063" checksum="ADB287953600C234" modified="2010-04-20" version="1">MRELVYTGFMSLDGVVDSPGGGPGEEHRGGGWVVKDVEFLPEAFALKEEELADTTALLFGRRSYEAFAPVWRDSEDHAAYKDLPKYVLSTTLTEDALVDGWGPTTILRSDDELAELKRGDGGAIFIHGSAELARRLSEAGLIDRYNLLVFPVLLGAGKSLFSRADLDKRVLRLRESEAYPNGVLKVIYALSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7T5</accession>
    <name>D3Q7T5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Epoxide hydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4786</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019998.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD44427">
        <property type="protein sequence ID" value="ADD44427"/>
        <property type="gene ID" value="Snas_4786"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4786"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_1_11"/>
    <dbReference type="OMA" id="ILMWVGE"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033961">
        <property type="term" value="F:cis-stilbene-oxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EHN" evidence="3">
        <location>
            <begin position="7"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="375" mass="41422" checksum="3001AB62EFC55804" modified="2010-04-20" version="1">MTNNNEIRSFRIDIPQADLDDLNDRLARTRLPRPAPTDDWEYGTPNSYLSATVAHWKDEFDWRAQEARMNAFPHYLTEIDGQNIHFIHVPSAEADATPLLLLHTYPGSFADFLDMIGPLTDPVTHGGDAADAFSVVVPSIPGMGFSTPLNGRGWTMRKVAESFDALMRRLGYDSYGAHGSDGGAMISRELGLLEPEGFLGLHVLQLFSFPSGDPAEFAKLGPKDHEALGHMQWFQSVGGYNQMNGTRPQTIGAAIADSPVGQLAYSELFNNFGNGTSLVTTEQILTQVSLYWFTNTQATAGRYHFEEGRAGTEPAVNHSRTGVAVFADDFTTIRAFAERDNSNIVHWSEFPDGGHFAAMERPDVLTGDLRQFFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q887</accession>
    <name>D3Q887_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42461">
        <property type="protein sequence ID" value="ADD42461"/>
        <property type="gene ID" value="Snas_2785"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2785"/>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006850_0_2_11"/>
    <dbReference type="OMA" id="YHAHDPA"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
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        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="945"/>
            <end position="1010"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1013" mass="108198" checksum="3A2F0A5D262A3CBE" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Z0</accession>
    <name>D3Q8Z0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_0888</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0888"/>
    <dbReference type="EnsemblBacteria" id="ADD40599">
        <property type="protein sequence ID" value="ADD40599"/>
        <property type="gene ID" value="Snas_0888"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0888"/>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_469964_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000951">
        <property type="entry name" value="Ph_dOase_redase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00409">
        <property type="entry name" value="PHDIOXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="8">
        <location>
            <begin position="344"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="7">
        <location>
            <begin position="570"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="657" mass="69679" checksum="448E724DBCBB4760" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q996</accession>
    <name>D3Q996_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Microbial collagenase</fullName>
            <ecNumber evidence="4">3.4.24.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Snas_2903</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Digestion of native collagen in the triple helical region at Xaa-|-Gly bonds. With synthetic peptides, a preference is shown for Gly at P3 and P1', Pro and Ala at P2 and P2', and hydroxyproline, Ala or Arg at P3'.</text>
            <dbReference type="EC" id="3.4.24.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.24.3" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018149.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2903"/>
    <dbReference type="EnsemblBacteria" id="ADD42578">
        <property type="protein sequence ID" value="ADD42578"/>
        <property type="gene ID" value="Snas_2903"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2903"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011878_1_0_11"/>
    <dbReference type="OMA" id="PTIWWIE"/>
    <dbReference type="OrthoDB" id="43759at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013661">
        <property type="entry name" value="Peptidase_M9_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002169">
        <property type="entry name" value="Peptidase_M9A/M9B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01752">
        <property type="entry name" value="Peptidase_M9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08453">
        <property type="entry name" value="Peptidase_M9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00931">
        <property type="entry name" value="MICOLLPTASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 13" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048332" description="Microbial collagenase" evidence="13">
        <location>
            <begin position="33"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M9_N" evidence="14">
        <location>
            <begin position="95"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="28"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD42578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="632" mass="69583" checksum="65CDF05369C2445F" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9A9</accession>
    <name>D3Q9A9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018162.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2916"/>
    <dbReference type="EnsemblBacteria" id="ADD42591">
        <property type="protein sequence ID" value="ADD42591"/>
        <property type="gene ID" value="Snas_2916"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2916"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107214_1_0_11"/>
    <dbReference type="OMA" id="HLEFTHH"/>
    <dbReference type="OrthoDB" id="1900922at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="134" mass="15281" checksum="58AD1CCAA0CBEAF7" modified="2010-04-20" version="1">MTYANAHVRIARPSTNLQAAERFWVEGLGLDVLWRVDPATDDHTEYALLMVGWTDAAWHLELADHPGEPVKPTPTDEDLLVIYLNGPVPDELVERLERCGGRRVTARNPYWDEWGVTIEDPDGYRLVLSTRDWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9D0</accession>
    <name>D3Q9D0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IIB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2937"/>
    <dbReference type="EnsemblBacteria" id="ADD42612">
        <property type="protein sequence ID" value="ADD42612"/>
        <property type="gene ID" value="Snas_2937"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2937"/>
    <dbReference type="eggNOG" id="COG0561">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044146_0_0_11"/>
    <dbReference type="OMA" id="QDTMIAR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="261" mass="26783" checksum="5580A9986B319491" modified="2010-04-20" version="1">MIATDLDGTLLDDEGRVSARTVRTLGRVRARGVAVVAVTARPPRVFDEWRELGGVVDAAICSNGGLTYVPGERRVESVRALDAGVAAVVVKALRAVVPSAAFAVETGFTVLAEPGYGWVDSVGHRRQRVGSFEEVLVRADQIVKLLMHDAAGRADEMVAAVRAAGVDGVEVSHSGGSGLVEMCAAGVSKATALERWCAGRGVGPQGVVAFGDAPNDVPMLSWAGRSFAMADAHAEAVAAASGRAGSNNADGVARVVEALVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9F2</accession>
    <name>D3Q9F2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2959</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2959"/>
    <dbReference type="EnsemblBacteria" id="ADD42634">
        <property type="protein sequence ID" value="ADD42634"/>
        <property type="gene ID" value="Snas_2959"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2959"/>
    <dbReference type="eggNOG" id="ENOG5032UPZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166931_0_0_11"/>
    <dbReference type="OMA" id="SFLKHEF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="92" mass="10100" checksum="BC0C1C6C274EB21C" modified="2010-04-20" version="1">MTRQKVLVLYLGTSALDSRVIGWAVYDGIGATSPTTGDSDEPPYATGVDALKDGWRLIQAAPLIPPYPGHEHDVSYLKHEFLFEQLVTEEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9X3</accession>
    <name>D3Q9X3_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Bacterioferritin</fullName>
            <ecNumber evidence="5">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_5032</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>4 Fe(2+) + 4 H(+) + O2 = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 7">Belongs to the bacterioferritin family.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020240.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5032"/>
    <dbReference type="EnsemblBacteria" id="ADD44669">
        <property type="protein sequence ID" value="ADD44669"/>
        <property type="gene ID" value="Snas_5032"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5032"/>
    <dbReference type="eggNOG" id="COG2193">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104506_2_0_11"/>
    <dbReference type="OMA" id="YQRLFHV"/>
    <dbReference type="OrthoDB" id="1890523at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:cellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00907">
        <property type="entry name" value="Bacterioferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002024">
        <property type="entry name" value="Bacterioferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002560">
        <property type="entry name" value="Bacterioferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00601">
        <property type="entry name" value="BACFERRITIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00754">
        <property type="entry name" value="bfr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00549">
        <property type="entry name" value="BACTERIOFERRITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 7" id="KW-0409">Iron storage</keyword>
    <keyword evidence="5 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="8">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR002560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR002560-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="160" mass="18630" checksum="FD6C0C3A2118883B" modified="2010-04-20" version="1">MRGDKQVIEFLNEQLTAELTAINQYFLHAKMQDNWGYVKLAKHTRAESMDEMRHAEVLTDRILYLEGLPNFQRLFALRIGENVPEMFANDMLIEVEAVDRLRRGIDHMRSVGDVTSAKIFEAILADEEEHIDYLETQQELISKLGENMYLQTLIEQPSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9X7</accession>
    <name>D3Q9X7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative glutamate--cysteine ligase 2</fullName>
            <ecNumber evidence="2">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Gamma-glutamylcysteine synthetase 2</fullName>
            <shortName evidence="2">GCS 2</shortName>
            <shortName evidence="2">Gamma-GCS 2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5036</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020244.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5036"/>
    <dbReference type="EnsemblBacteria" id="ADD44673">
        <property type="protein sequence ID" value="ADD44673"/>
        <property type="gene ID" value="Snas_5036"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5036"/>
    <dbReference type="eggNOG" id="COG2170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044848_0_0_11"/>
    <dbReference type="OMA" id="WAGRDTG"/>
    <dbReference type="OrthoDB" id="991285at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042398">
        <property type="term" value="P:cellular modified amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01609">
        <property type="entry name" value="Glu_cys_ligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011793">
        <property type="entry name" value="YbdK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02050">
        <property type="entry name" value="gshA_cyan_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="392" mass="42886" checksum="4E712EB6E01E9834" modified="2010-04-20" version="1">MAGTAQHAHITRFIDPVPPTAGIEEEFFLVDPHTRRVAPDAAEVVRRAGTWSGGSISTEFTKYQVETRTDPFSDVDDLATEVARMRDIAATAATEAGLRVTATGTPVQGDIVPPPIADIPRYRETTAMFRTLQDGQSISACHVHVHMPDPELAVLVSNHLRPWLPVLLSMNGNSPYWAGRDTGYASWRTLSWSGWPVAGPPPYYESRDHFDELVGTLVAGGALMDRRSIFWDVRPSAHLPTIEVRVADVAATAFEGPLFAALVRALVTLAAQAVRHGDRGPRTAPELLRAASWRAARDGLEGKGIDTRTGKLRDAGQLVESLLAEVRPILTVWGEWDRVTGWWQRLRSIGSGAARQRAAYAERGHLDDVVDCLIEQNRPGSLHKGRTVVHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA09</accession>
    <name>D3QA09_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016292.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1011"/>
    <dbReference type="EnsemblBacteria" id="ADD40721">
        <property type="protein sequence ID" value="ADD40721"/>
        <property type="gene ID" value="Snas_1011"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1011"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080407_0_0_11"/>
    <dbReference type="OMA" id="DARIVHQ"/>
    <dbReference type="OrthoDB" id="1661714at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="125"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="235" mass="25865" checksum="B66BABBCEFB575BC" modified="2010-04-20" version="1">MKSRKSGLRTVDVARGAGYSVQQVRILERDGVLPPVERTASGYRIYAEAHVQAAIAYRELAAGLGPVDAKQLMRTALNRPTAELLASLDAEHADLHAERRRLRLARKAAESITAEPLDDVRPSDVMSIGELAEALGVRASTLRHWEYEGLVAPDRTVGRRVRSYSPAAVRDARIAHQLRLAGYRIDALRTLIPQLSTTRDHDEVLKGLSARDSRLDERSRALLHGTAALVAMNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA24</accession>
    <name>D3QA24_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_1026</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016307.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1026"/>
    <dbReference type="EnsemblBacteria" id="ADD40736">
        <property type="protein sequence ID" value="ADD40736"/>
        <property type="gene ID" value="Snas_1026"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1026"/>
    <dbReference type="eggNOG" id="COG4988">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_9_11"/>
    <dbReference type="OMA" id="EYFLPFR"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="24"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="396"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="316"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="465"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="430"/>
            <end position="437"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD40736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="681" mass="70732" checksum="243C6EF57823F0E1" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA32</accession>
    <name>D3QA32_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1034</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1034"/>
    <dbReference type="EnsemblBacteria" id="ADD40744">
        <property type="protein sequence ID" value="ADD40744"/>
        <property type="gene ID" value="Snas_1034"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1034"/>
    <dbReference type="eggNOG" id="COG1174">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_7_2_11"/>
    <dbReference type="OMA" id="FGPVRRY"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="31"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="227" mass="23902" checksum="B0762FAB4880565E" modified="2010-04-20" version="1">MSLSIGLDDPRNPWFSWSYIEDNAATLGSALLEHLELTVVSVVVAAVISIPLGILSARSRLAATVILSGSGVLYTIPSLAVFALLAPFLGQSLITVEVGLVMYAMLIIVRATLTGLRQVPPDVIDAAGGMGYSRVHLLTRVELPLAVPSIMTGLRIATVSTVAMVTIGAVVGHGGLGGLILTGFRNNLYKPQILTATILCIALALAFEVLLSLVTRLMTPWTRGRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA58</accession>
    <name>D3QA58_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016341.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1060"/>
    <dbReference type="EnsemblBacteria" id="ADD40770">
        <property type="protein sequence ID" value="ADD40770"/>
        <property type="gene ID" value="Snas_1060"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1060"/>
    <dbReference type="eggNOG" id="ENOG5031X0K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1561932_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="171" mass="17619" checksum="B087E2A1E6FE90A7" modified="2010-04-20" version="1">MSNNTEPHAEAGPPADETDENTNPPARTKLVAATILAVAALFGGAVVFGGLWLTGQWDGPSADDPAESVDGFLTALFTEHDAKDAASYTCASQSGDLGKVVDELDDAAAAAQFSWSKVTTVETDGSSAVVTAKVTHDVSGESAVWTFALVTGDPDDAWRVCGVITDDKSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAF9</accession>
    <name>D3QAF9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3071"/>
    <dbReference type="EnsemblBacteria" id="ADD42742">
        <property type="protein sequence ID" value="ADD42742"/>
        <property type="gene ID" value="Snas_3071"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3071"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_6_11"/>
    <dbReference type="OMA" id="HFDWHDE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="32"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="31957" checksum="8F078D3D9E2DE5D7" modified="2010-04-20" version="1">MTHVTGSVSLGIFVGPWYLAETMADNTILVIGSTGKIGRHVAERLRERDVTVKAASRSGPVHFDWHDEATWPGALDGAQGAYLVDSQDADRVPLLRRFSALAAHRGLRRLVFLSAREAESVNPTLEEKEAAIKDAGTEWTILRPVWFNQNFSEVAAFREPLRAGELRLPAGDGPQPFIDAEDIAEVAAAALTTDGHHGRTYDLSGPEAISFGEAVAHIAKATGRDLRYRPVSAEDYVADPAAFGAQPGQAEGYALLMAAIAEGKTSHLSDGVKQALGRDPRGFAEYAVKTAATGVWDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAN7</accession>
    <name>D3QAN7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020254.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5046"/>
    <dbReference type="EnsemblBacteria" id="ADD44683">
        <property type="protein sequence ID" value="ADD44683"/>
        <property type="gene ID" value="Snas_5046"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5046"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147343_0_0_11"/>
    <dbReference type="OMA" id="HPNSPIY"/>
    <dbReference type="OrthoDB" id="1846332at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="146" mass="16419" checksum="29C609F9A8DC4F70" modified="2010-04-20" version="1">METPQFFGVNVEIALRRGERWLLIERGRRLRNAPGMLAFPGGRVEAEANCGFILEDTARREAAEEVGLDLSDVSLRYVRSEFFVGDDGNRYIGATFTAELPRGREPRVAAPEEVEAVHWLTADEVKNHPKCPEWTLLSLSYAASVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAR8</accession>
    <name>D3QAR8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sodium/hydrogen exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_5078</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5078"/>
    <dbReference type="EnsemblBacteria" id="ADD44714">
        <property type="protein sequence ID" value="ADD44714"/>
        <property type="gene ID" value="Snas_5078"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5078"/>
    <dbReference type="eggNOG" id="COG0025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005912_8_2_11"/>
    <dbReference type="OMA" id="IRREDAT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="PTHR10110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0915">Sodium</keyword>
    <keyword evidence="5" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="8">
        <location>
            <begin position="7"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="585"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="763"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="585"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="650"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="685"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD44714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="829" mass="89295" checksum="EC58AB1F4CC15344" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAX5</accession>
    <name>D3QAX5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020342.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5136"/>
    <dbReference type="EnsemblBacteria" id="ADD44771">
        <property type="protein sequence ID" value="ADD44771"/>
        <property type="gene ID" value="Snas_5136"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5136"/>
    <dbReference type="eggNOG" id="ENOG5033VT1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1427219_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="190" mass="19656" checksum="9A3F1F1F18EC68A6" modified="2010-04-20" version="1">MNDFADDTSMDDAGTEDNLDYDDVDLNGDGIADHTMETDDGTSVDVNNDGTVDGVITDDGSAYYDSDGNGTFDQHLVDSNADGYVDVVESDLNEDGQVDQTSSDTNYDGFVDQVDTDTTGDGVADTSTADTNGDGFADTTASDADQDGATDSTFTDNNGDGVADDVTYTDSEIDEGAGLGNESANPYAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB05</accession>
    <name>D3QB05_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome bd ubiquinol oxidase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Snas_1112</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016393.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1112"/>
    <dbReference type="EnsemblBacteria" id="ADD40822">
        <property type="protein sequence ID" value="ADD40822"/>
        <property type="gene ID" value="Snas_1112"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1112"/>
    <dbReference type="eggNOG" id="COG1271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030555_3_3_11"/>
    <dbReference type="OMA" id="RWWITND"/>
    <dbReference type="OrthoDB" id="271551at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="221"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="351"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="422"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD40822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="477" mass="51989" checksum="5BF40FF462A9A09A" modified="2010-04-20" version="1">MDTLELARLQFATTTGIHWLFVMLTLGLVPLVAIVNTRAVFTRDADKREGLVRLAKFWGQLYVINYALGIVTGLVMEFQFGLSWSGLSEFAGNVFGAPLALETMIAFFAESTFLGMWIFGWDRLRLGTQAVLIWLVCLTAYASAFWILVANGFMQSPVGYEVREGRAYLTDFAAQLTNPNATVAFGHILTAALLTGGLFVAGVSAFHLLRRTREREFFRTGLRTGVIAAAASTFPVYMLGAAQFAVLADSQPMKLALLAGEGTSELQKDMVERHGPGDYVPPEWIETWLHTMANIGYLVSTLALCALLVLFRARFTRSRLLAIVMVLAVGGLFGLYLGSYLFDTPGPYNEIIMPACIALAAVVLGFGGRIRRWRGLGWLLVVAIPLPFVASVGGWLFREVGRQPWIVYGELKVSDAVSPVSFGHMLTSLVIFVGVLGALAVTNWTLIARFARRGPAASQLGVARDEVPVLETVGSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBP4</accession>
    <name>D3QBP4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3256"/>
    <dbReference type="EnsemblBacteria" id="ADD42926">
        <property type="protein sequence ID" value="ADD42926"/>
        <property type="gene ID" value="Snas_3256"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3256"/>
    <dbReference type="eggNOG" id="COG1246">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_933540_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="33176" checksum="866BF6E1313699EE" modified="2010-04-20" version="1">MLREATTTDIPAIATLMRQSVLDTFPLFHDERETAAAARYLTEPDTVLIDDGTYYVHEANGQIVACGGWSKRDKLYTGSGDAPTDDRLLDPATEPARVRAMFVRGDWTRRGLGRAILTRCEHDARAQGFTTLVLMATLPGEPLYRSFGFRERARTRVPLPNGVTLDGVSMEYPLLQRRVHLHTGAFQHRPQFRARIPAHLTGDRRDLEKPRHQATDVLGVRRTGGRVAIALVNERLGALGVEVHVVLDGAGVLSAHDLLRLGDKAFELLQLAVADHQARRAVHLGHRLRHGRNLTPHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBP7</accession>
    <name>D3QBP7_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyoxalase-like_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018500.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3259"/>
    <dbReference type="EnsemblBacteria" id="ADD42929">
        <property type="protein sequence ID" value="ADD42929"/>
        <property type="gene ID" value="Snas_3259"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3259"/>
    <dbReference type="eggNOG" id="ENOG5033SJD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1299115_0_0_11"/>
    <dbReference type="OrthoDB" id="1636328at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025870">
        <property type="entry name" value="Glyoxalase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13468">
        <property type="entry name" value="Glyoxalase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase-like_dom" evidence="1">
        <location>
            <begin position="3"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="212" mass="22563" checksum="6461EE45CCBF5689" modified="2010-04-20" version="1">MEIDHVVLAARGKTEAEEVLDQAGLGVARGRTLPGLGLSNLVVPLRHGQILEVHYPNGETPAADAPPLLRFDTDALDTHPAHTLIPMAWLVVIEDAARLRDLAAAHDMSVIEAPAEGPEFPPYTLAGFGANFERRFLPCLIHWPQGQPVLDAPHRRRPLGITGIDVAGPVGTIEDWCGGEPDGLRTLPGTSGPVRVTVGFAEGPPVTFGLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC26</accession>
    <name>D3QC26_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020486.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5281"/>
    <dbReference type="EnsemblBacteria" id="ADD44915">
        <property type="protein sequence ID" value="ADD44915"/>
        <property type="gene ID" value="Snas_5281"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5281"/>
    <dbReference type="HOGENOM" id="CLU_349803_0_0_11"/>
    <dbReference type="OrthoDB" id="402800at201174"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="805" mass="89470" checksum="A5BF65E95E524E84" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU23</accession>
    <name>D3PU23_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016540.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1260"/>
    <dbReference type="EnsemblBacteria" id="ADD40969">
        <property type="protein sequence ID" value="ADD40969"/>
        <property type="gene ID" value="Snas_1260"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1260"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_12_4_11"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="18"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="222" mass="23965" checksum="1989FB67FD3C8747" modified="2010-04-20" version="1">MTATKPRKAGRPRKEEATDTRTVLLDAALKLFVAKGFAATSVRMIARAAGLSDGGLYAHFPSKQAVYDELLASAGPGVVDGMVAELLPEAGTPPQDPETFLTQLVGRILDYFETPAARDFSLLLLREEIPGNGDLVTAMIDKGAAALGPVVTEWAKAGHLPDRVRQRLDAGTVTGESLMWELLAPLGFVRLVYLHGTDESRAEGRRRADAHLEFFLNAVVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUX2</accession>
    <name>D3PUX2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5363</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020567.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5363"/>
    <dbReference type="EnsemblBacteria" id="ADD44996">
        <property type="protein sequence ID" value="ADD44996"/>
        <property type="gene ID" value="Snas_5363"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5363"/>
    <dbReference type="HOGENOM" id="CLU_1488185_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="181" mass="19797" checksum="BB0ED1E29FCD715F" modified="2010-04-20" version="1">MVVVSTFSELMDRLRIKVASPDGTVKLRFDSKGAAIVLTEGCLERHSEQSLAAAVDRCLESLSRAYDSAKDGIFDKSGGAPAVERRGVRKDDRLERYWAELAAIRVQGISSRGFVTMERVQGRVTTVVAPRALTRCNTGDMEAELNGALSEVSQRYSAAVTAAYCREYFTVEVAKLPPFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV22</accession>
    <name>D3PV22_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016646.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1368"/>
    <dbReference type="EnsemblBacteria" id="ADD41075">
        <property type="protein sequence ID" value="ADD41075"/>
        <property type="gene ID" value="Snas_1368"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1368"/>
    <dbReference type="eggNOG" id="COG1725">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_10_1_11"/>
    <dbReference type="OMA" id="DGAPPYE"/>
    <dbReference type="OrthoDB" id="1860081at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="119" mass="12877" checksum="AC76E04BF4CBD79E" modified="2010-04-20" version="1">MILAVDNTSPVPPYEQVRSELARQINDHVLPVGTRLPTVRKLADDLGLAPNTVARSYRELEEAGLIETRGRAGSFVSAAGDVSRQRVNAAAEQYAEAVRRLGIDRAEALDIVAAALDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV34</accession>
    <name>D3PV34_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1380"/>
    <dbReference type="EnsemblBacteria" id="ADD41087">
        <property type="protein sequence ID" value="ADD41087"/>
        <property type="gene ID" value="Snas_1380"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1380"/>
    <dbReference type="HOGENOM" id="CLU_576062_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="474" mass="52945" checksum="127133FF29516922" modified="2010-04-20" version="1">MSHGSVPRDLLSTQSTFVCDLVPRLLALAGDPDADHPVVLLSGPSGSGHTKALETAQQCARHTPNVLVTFKKDTTSNASDSPDPMELLHLLAVMVSKLRRRYPRFGSIPFLRFQLCYDILTANIDLNTDPEAVTTVRGRVRQRIFGRIPQPSPETLDAVDKFATVASTRPPGLLAGMVWVVSLIKWPLWWIRAWQLHRSFRDMSTFTTGNDATQCLITLWNWFKSKRSTDFKQGEKALCEAFLADLGNFHRWHPRRTSCLVLLDHIPNPLNTDTKHPATRLLRYITALRANPESHLSPRTAAAGYGGPNPLAAQPRKRLPGHAALTIVAVTEKLNGQSRSNLRQNEPPMAAVSHALTAWQQWFPGNQALPKSWYCHTYLPPLTAEDVKLLNPTPPSLSDAAVRWLLEFHTSRPYVIQELIAALEKLDEPTRAEILSSQPSRRSIAWLCRELPSDIHESVHAELSRRNDPGSTDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV66</accession>
    <name>D3PV66_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">map</name>
        <name evidence="5" type="ordered locus">Snas_1412</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016690.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1412"/>
    <dbReference type="MEROPS" id="M24.A06"/>
    <dbReference type="EnsemblBacteria" id="ADD41119">
        <property type="protein sequence ID" value="ADD41119"/>
        <property type="gene ID" value="Snas_1412"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1412"/>
    <dbReference type="eggNOG" id="COG0024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015857_2_1_11"/>
    <dbReference type="OMA" id="GDHAYTF"/>
    <dbReference type="OrthoDB" id="1285136at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="48"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="298" mass="33084" checksum="F922124278E04481" modified="2010-04-20" version="1">MTVRAALKPGVQTPRREVPAHIVKPEYVGKPKPQPFTGSHVKDADTIERMRIAGRLAADSLVEVGKQIKPGVTTDELDKFVHEYLCDHGAYPSTLGYKGFWKSCCTSLNEVICHGIPDSTVVEDGDIVNVDITAYINGVHGDNNATFLVGDVDEEVRTLVERTYEATMRGIKAVAPGREINVIGRVIEAYAKRFDYGVVRDFTGHGIGESFHSGLHILHYDNPKQKTIMEPGMTFTIEPMINLGTYRHDMWADGWTAVTKDRKWSAQFEHMIVVTETGHEILTMPTSGPSAGTPEKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVB8</accession>
    <name>D3PVB8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1467</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016742.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41171">
        <property type="protein sequence ID" value="ADD41171"/>
        <property type="gene ID" value="Snas_1467"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1467"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1266136_0_0_11"/>
    <dbReference type="OMA" id="QDHPVGR"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="17"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="217" mass="23293" checksum="5F0F7A9F22C0A0BB" modified="2010-04-20" version="1">MTPPTDDTRPTQAERRARTRDALLEAAARGLSEYGYGSLSLAKVAAEAGYTRGALYHQFANKEELALAVVAWVDQTWTAEVEEPAKRLSAPAEILLAIARGHAIYCRRNVARVMMTLRIEFAGREHPVGRAIMDLAGEFLDNCAQWIVEGRADGSIPPGPPPQATATAYLGALEGLMVLLAGQEPHDVELAERMARGVLGLPPLASDTAGLGRHQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVN8</accession>
    <name>D3PVN8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43152">
        <property type="protein sequence ID" value="ADD43152"/>
        <property type="gene ID" value="Snas_3489"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3489"/>
    <dbReference type="HOGENOM" id="CLU_394267_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="485"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="510"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="555"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="597" mass="61275" checksum="4E0622D1108B33BD" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVR0</accession>
    <name>D3PVR0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anhydro-N-acetylmuramic acid kinase</fullName>
            <ecNumber evidence="1">2.7.1.170</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">AnhMurNAc kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">anmK</name>
        <name evidence="2" type="ordered locus">Snas_3511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1,6-anhydro-N-acetyl-beta-muramate + ATP + H2O = ADP + H(+) + N-acetyl-D-muramate 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:24952"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58690"/>
            <dbReference type="ChEBI" id="CHEBI:58722"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.170"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-sugar metabolism; 1,6-anhydro-N-acetylmuramate degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan recycling.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anhydro-N-acetylmuramic acid kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.170" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018745.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3511"/>
    <dbReference type="EnsemblBacteria" id="ADD43174">
        <property type="protein sequence ID" value="ADD43174"/>
        <property type="gene ID" value="Snas_3511"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3511"/>
    <dbReference type="eggNOG" id="COG2377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038782_0_0_11"/>
    <dbReference type="OMA" id="GQTIRHE"/>
    <dbReference type="OrthoDB" id="736294at2"/>
    <dbReference type="UniPathway" id="UPA00343"/>
    <dbReference type="UniPathway" id="UPA00544"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097175">
        <property type="term" value="P:1,6-anhydro-N-acetyl-beta-muramic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006040">
        <property type="term" value="P:amino sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01270">
        <property type="entry name" value="AnhMurNAc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005338">
        <property type="entry name" value="Anhydro_N_Ac-Mur_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30605">
        <property type="entry name" value="PTHR30605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03702">
        <property type="entry name" value="AnmK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="390" mass="39585" checksum="E7C7E5BEBBEE67C4" modified="2010-04-20" version="1">MRVLGMISGTSHDGIDTAIVDFGADGDRLHGRIVHTGSHPYPTGLRSRLAAALPPAETTLSEVCELDTLIGQTFASAAAEAILASGDVDLIVSHGQTVYHWVEGGHAHGTLQIGQPAWIAERTGAPVLSDVRIRDITAGGHGAPLVSYMDTLLLAGVDGVPAALNLGGIANISIPRGAGDVTAYDIGPANALIDAAVVRHGGHPAGFDEDGRIAASGTVDEALLAVLLADAYYRLPAPKSTGKEHFHIGYVDQAVATAGSQIGFADLVATLTELTIRTVADDVRAAGVTKLLVSGGGAHNPVIMDGLRSALTGTEVASSDTLGAPADDKEAIAFALIGWCTAHGLPGSNPAGTGARSARILGTLTPGAGPLTLPTPLTRAPRSLVLEPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW73</accession>
    <name>D3PW73_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1526"/>
    <dbReference type="EnsemblBacteria" id="ADD41230">
        <property type="protein sequence ID" value="ADD41230"/>
        <property type="gene ID" value="Snas_1526"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1526"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_11"/>
    <dbReference type="OMA" id="PCGATTS"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="2">
        <location>
            <begin position="13"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="313" mass="32149" checksum="BF92D3423FC2F1C1" modified="2010-04-20" version="1">MTRMYAITQDGFGGPEVLHRTETDRPTPGPDDVLVKVHAAGVNPVDTAVRAGYFPLITEPPFALGWDVAGVVEAVGANVTRFSVGDAVFGMPLFPEAAGAYAQYLTAPAGQLVPKPDSLSMAEAGALPLAGLTAWQAVVDIAEVAAGQRVLIHAAAGGVGHLAVQIAKSRGAHVIATARAANHELVKSLGADEVIDYTAVDFTTAIEPVDVVVDLVGGDYAPRSARVLRPGGLLVTTVGHNPGITEVEAEQAGIRYATVFVMPSAKNLAGLSALSEAGELRVHVAERLPLAEAAKAHELAESGGAVGKTVLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWD9</accession>
    <name>D3PWD9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease NucS</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nucS</name>
        <name evidence="3" type="ordered locus">Snas_1593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NucS endonuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1593"/>
    <dbReference type="EnsemblBacteria" id="ADD41296">
        <property type="protein sequence ID" value="ADD41296"/>
        <property type="gene ID" value="Snas_1593"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1593"/>
    <dbReference type="eggNOG" id="COG1637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069350_0_0_11"/>
    <dbReference type="OMA" id="RCSVDYA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00722">
        <property type="entry name" value="NucS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002793">
        <property type="entry name" value="Endonuclease_NucS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38814">
        <property type="entry name" value="PTHR38814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01939">
        <property type="entry name" value="NucS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="234" mass="25626" checksum="3266FF1EC9FAE9F4" modified="2010-04-20" version="1">MLGLGLALATLSRMRLVIARCSVDYTGRLSAHLPMAPRLLMLKADGSILVHADGGSYKPLNWMTPPCSLKEEDGLWTVTNNKSGDTLRITIEEILHDTTHELGVDPGLQKDGVEAHLQELLAADPTPIGEGYSLVRREFPTAIGPVDLMCRDSEGVSVAVEIKRRGEIDGVEQLTRYLELLNRDPLLAPVQGVFCAQVIKPQARVLAEDRGIRCVTVDYDTLRGTVDDSQPTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWE1</accession>
    <name>D3PWE1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HEPN_Swt1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016869.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1595"/>
    <dbReference type="EnsemblBacteria" id="ADD41298">
        <property type="protein sequence ID" value="ADD41298"/>
        <property type="gene ID" value="Snas_1595"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1595"/>
    <dbReference type="eggNOG" id="COG1483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010124_0_0_11"/>
    <dbReference type="OMA" id="KTHTMLA"/>
    <dbReference type="OrthoDB" id="55634at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007555">
        <property type="entry name" value="DUF499"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041650">
        <property type="entry name" value="HEPN_Swt1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04465">
        <property type="entry name" value="DUF499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18731">
        <property type="entry name" value="HEPN_Swt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN_Swt1" evidence="1">
        <location>
            <begin position="11"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="1109" mass="123259" checksum="1C22448DBE38C071" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWU6</accession>
    <name>D3PWU6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exodeoxyribonuclease 7 large subunit</fullName>
            <ecNumber evidence="5">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Exodeoxyribonuclease VII large subunit</fullName>
            <shortName evidence="5">Exonuclease VII large subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">xseA</name>
        <name evidence="10" type="ordered locus">Snas_5539</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the XseA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020741.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5539"/>
    <dbReference type="EnsemblBacteria" id="ADD45170">
        <property type="protein sequence ID" value="ADD45170"/>
        <property type="gene ID" value="Snas_5539"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5539"/>
    <dbReference type="eggNOG" id="COG1570">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023625_2_1_11"/>
    <dbReference type="OMA" id="WPAVRFE"/>
    <dbReference type="OrthoDB" id="1371775at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04489">
        <property type="entry name" value="ExoVII_LU_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00378">
        <property type="entry name" value="Exonuc_7_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025824">
        <property type="entry name" value="OB-fold_nuc-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13742">
        <property type="entry name" value="tRNA_anti_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00237">
        <property type="entry name" value="xseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_anti_2" evidence="9">
        <location>
            <begin position="25"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="8">
        <location>
            <begin position="141"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="8">
        <location>
            <begin position="347"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD45170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="414" mass="45160" checksum="A3C9F2F8EFBC5F68" modified="2010-04-20" version="1">MLSHVTQPELAAATGPSTPESPWPVRVVSHKIGEWISRLGAVWAEGQITQISRRPGAGFVFLTLRDPAAEVSLTVVTTRNVVDACDPPLRDGARVIVHGKPDWYPGRGTLSLRATEIRQVGLGELLARLEKLKKLLAAEGLFAPERKRPLPFLPRRIGLITGRASAAERDVLENAKTRLPSADFEVREVPVQGPQAVPKVLEALAELDADPAVEVIILARGGGSVEDLLPFSDETLCRAVFAAKTPIVSAIGHEPDNPLVDFVADVRCSTPTDAGKRVVPDFAEERRGIDQARHRLRQALGGKIDRESQALAAMRSRPCLAQPSRIIDDRQDEITHARDRIRRAFTARLDKAAHDVTSLRGHLRALSPQGTLDRGYAIVRRADGAVVRADTEVTASEDLRVRLARGELTVIVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX03</accession>
    <name>D3PX03_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5597"/>
    <dbReference type="EnsemblBacteria" id="ADD45227">
        <property type="protein sequence ID" value="ADD45227"/>
        <property type="gene ID" value="Snas_5597"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5597"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_2_3_11"/>
    <dbReference type="OMA" id="HATHYST"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="406" mass="43876" checksum="2FB26585ADB6DCA3" modified="2010-04-20" version="1">MPDQGFVSAAGQPRCHIRNRGKDTEMTNDRAALREALEWGVEQGAPSVAVQVSDADGTWFDAVGKSDLVTGAEREPGEQLHTGSISKAFTAVAALNLAAEGRLSLDDTVEKWLPGTANGNGYDGSTITLRHLLNNTSGLFATGMAVEVQNRYNKRSAFDKHRHDVWEIDDVLKLAVSEPPVGEPGEKFWYSNGGFGFAGAIIERASGASLESEVERAVRPLGLANTFMRERADEGYRGPHPKAYSKLFVKEGVRPEDVTAENWQSMMEGPELEPFDTTDVNTSGGYGAANVVSNFDDLLVFYKALITGSLLPQEQNAELWNTVSTKGGYWMLNSRYGLGVCELTLSDGQKVRGGGGQSFGTITLVLGSPDGERMVAMHTNNDWLTFPVFDRITEAVFGANGIGLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXA6</accession>
    <name>D3PXA6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016940.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1667"/>
    <dbReference type="EnsemblBacteria" id="ADD41369">
        <property type="protein sequence ID" value="ADD41369"/>
        <property type="gene ID" value="Snas_1667"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1667"/>
    <dbReference type="eggNOG" id="ENOG50309SY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_816167_0_0_11"/>
    <dbReference type="OMA" id="WWRVTAV"/>
    <dbReference type="OrthoDB" id="1418965at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="336" mass="36250" checksum="FF4627E356D89075" modified="2010-04-20" version="1">MWRRFGPVIGLFLLAPFFGEFVLGNLTLSELPLGVLLAPMYGCGALLVRELGRRFGGGWPTMALLAVAYALAEEGPIDQLLWNDSYAGHDYISGPSYVPVLGTSVAAIQVVIALHAVWSICVPIAIAEAFTRDRRTTPWLRLPGLTVVGVLWVAGSLLVFYGNYVEERFMASPAQFITAGVVIGALIVAAFAIRGRRLAPMAGPAPAPWLVGGFGLVATSLYWAPNNLVTDTLSFEWIGVAIWFLVVAVGVFAVSRWSRRDGWDHRHRYALGAGAALTYVWMSFPVRPETGGSVTVDLVSNVVIGTLAVLILWLAWRRVHNGPSATSTVNGFQSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXD6</accession>
    <name>D3PXD6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016970.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1700"/>
    <dbReference type="EnsemblBacteria" id="ADD41399">
        <property type="protein sequence ID" value="ADD41399"/>
        <property type="gene ID" value="Snas_1700"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1700"/>
    <dbReference type="HOGENOM" id="CLU_1969193_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="127" mass="14429" checksum="313C00698456BA4C" modified="2010-04-20" version="1">MSEPDWPENAYQLRYLCLNDAVRCLRQAGLEDHATRLFTLPVDGESPLNDILDALGWRQDYEEWRADMNLRGCFTAYPGRKARLRPVYGCPLDAELRCGRELQGDSTPPPCGITSGPMRHDRDEFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXW9</accession>
    <name>D3PXW9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">4-diphosphocytidyl-2C-methyl-D-erythritol synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">MEP cytidylyltransferase</fullName>
            <shortName evidence="7">MCT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ispD</name>
        <name evidence="8" type="ordered locus">Snas_5668</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>2-C-methyl-D-erythritol 4-phosphate + CTP + H(+) = 4-CDP-2-C-methyl-D-erythritol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="EC" id="2.7.7.60"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.60" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020869.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5668"/>
    <dbReference type="EnsemblBacteria" id="ADD45298">
        <property type="protein sequence ID" value="ADD45298"/>
        <property type="gene ID" value="Snas_5668"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5668"/>
    <dbReference type="eggNOG" id="COG1211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061281_2_1_11"/>
    <dbReference type="OMA" id="ERQHSVY"/>
    <dbReference type="OrthoDB" id="525632at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00093"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050518">
        <property type="term" value="F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02516">
        <property type="entry name" value="CDP-ME_synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00108">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001228">
        <property type="entry name" value="IspD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034683">
        <property type="entry name" value="IspD/TarI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018294">
        <property type="entry name" value="ISPD_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01128">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00453">
        <property type="entry name" value="ispD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01295">
        <property type="entry name" value="ISPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5 7 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="7">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="7">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="239" mass="25551" checksum="49AE27E9C0A5050E" modified="2010-04-20" version="1">MSSPVVAVLPAGGTGTRLGSALPKQLIKIDGREILAHTLDVFEATPEVDEIFVFPPREHVAVVEELVKSYGFGKVRGVAPGGADRAASVRAGLAALSDHPSDTKVLVHDAVRPLVDVATVTECVTALDELEAVTVAVPSTDTIVEVDVSGPRELISGIPDRSRLRRCQTPQAFRLRTLARAHELAVADVNFTPTDDCGVVRRYLPHMAIGIVPGSEDNLKITYPGDLRVAAELLRDRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXZ2</accession>
    <name>D3PXZ2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5667 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5691"/>
    <dbReference type="EnsemblBacteria" id="ADD45321">
        <property type="protein sequence ID" value="ADD45321"/>
        <property type="gene ID" value="Snas_5691"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5691"/>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061725_0_0_11"/>
    <dbReference type="OMA" id="HDASEGH"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043725">
        <property type="entry name" value="DUF5667"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18915">
        <property type="entry name" value="DUF5667"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5667" evidence="2">
        <location>
            <begin position="88"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="330" mass="34021" checksum="1D7F0122A5E99FB2" modified="2010-04-20" version="1">MKVSEALHQTARETRESTAPRPEFQAALRQRLLAVAATQGIGATAEHTETPATQAKQPMSGGRRMIVASALAVGVLGLSGVSTASADALPGDALYPVKRSAERAQLALAGSEVNRGQLYFEFARTRLDEAGRVSGNPEALNTTLSDMDSQLASGMKSLTSAAVNRQDAGVLDTIDEFLDGQSPKLANLLDDAPNEAHTSLGDSMDLMDSAAERSQELREALLCAASFDDDTDKLGPLPGECGVLPGEDGTPLDVPTDDENPASTQETGSGTTGSGDTSTDAESESPSPQPGRKGDKNSDESPSPTSPSPTADNGGGLLGEIGDTLDDLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYB8</accession>
    <name>D3PYB8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1788"/>
    <dbReference type="EnsemblBacteria" id="ADD41485">
        <property type="protein sequence ID" value="ADD41485"/>
        <property type="gene ID" value="Snas_1788"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1788"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_0_11"/>
    <dbReference type="OMA" id="HRRSEIM"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="194" mass="21589" checksum="004F443781CA32FA" modified="2010-04-20" version="1">MTGRGPGKTLRVDAQRNHEQIMATALRLLPEHGPDMPMEELARAAEVGVGTLYRRFGGREQLIEACAAAAFTSVTTHAQRAEAETDGWSALSTFILDAAPDLMVVGCLSTWYPDSWRKVKASQAEQHRRSEIMAVLDRLVRQAQEQGRMRDDVDVDDVAMMLALVLRPIPGRTDTLDATRRYVSLMLDGLRTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYK9</accession>
    <name>D3PYK9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3785</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019013.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3785"/>
    <dbReference type="EnsemblBacteria" id="ADD43442">
        <property type="protein sequence ID" value="ADD43442"/>
        <property type="gene ID" value="Snas_3785"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3785"/>
    <dbReference type="eggNOG" id="COG0609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013016_1_0_11"/>
    <dbReference type="OMA" id="ITYWQMG"/>
    <dbReference type="OrthoDB" id="1283908at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="336" mass="33495" checksum="B137F58608C00C02" modified="2010-04-20" version="1">MTTTPATTRSPAARHVLVLAAGLVLLAAAVIVGLGVGARSVPPAEVVRALFAFDGGDDHLVVHDVRIPRALLGIGVGAALAVAGVLIQTLTRNPLAEPGLLGVTSGAGFTVILGAAAGLATGAVTELGFAALGAVAAATLVYAVGRSSPLRLVLTGVALSAVLTGIGLGLRLMLPDVFDQYRFWSVGSLAGREQAPLAVPLTVIGLALVAALLLSRPLAAVSLGDTVAHTLGANVTRIRLSALIVVTTLVGAATAVAGPILFVGLIVPQLARRLATGSVGWLIGYAVVLGAILMLAADTIARVLLPTGEVPVAIVTAFLGGPALIAAVRRDRTVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYN8</accession>
    <name>D3PYN8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+/solute symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3815</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019042.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3815"/>
    <dbReference type="EnsemblBacteria" id="ADD43471">
        <property type="protein sequence ID" value="ADD43471"/>
        <property type="gene ID" value="Snas_3815"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3815"/>
    <dbReference type="eggNOG" id="COG4147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018808_8_3_11"/>
    <dbReference type="OMA" id="GTTWVQM"/>
    <dbReference type="OrthoDB" id="278483at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="495"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="534"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="584" mass="60363" checksum="3387901EE291E4E4" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYS1</accession>
    <name>D3PYS1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3848</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019075.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3848"/>
    <dbReference type="EnsemblBacteria" id="ADD43504">
        <property type="protein sequence ID" value="ADD43504"/>
        <property type="gene ID" value="Snas_3848"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3848"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_22_0_11"/>
    <dbReference type="OMA" id="HNVANPD"/>
    <dbReference type="OrthoDB" id="1335404at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014303">
        <property type="entry name" value="RNA_pol_sigma-70_ECF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02957">
        <property type="entry name" value="SigX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="7"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="105"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="292" mass="32304" checksum="EEA5C98866649DCB" modified="2010-04-20" version="1">MATATELFEQHRNLLFSVAYRMLGSAADAEDVVQDSWLKWSAVDLDTVDSPKAYLVRIASNTALNRLKSAQVQRESYVGPWLPEPILTSPDIAEDVEMADSVSMAMLVVLESLTPEERAVFVLREVFGFPHTEIASALDRPEASVRQLAHRARSHVQARRPRFDADREKQKQATEEFLSAAAGGDINRLMEILAPDAALWTDGGGKVKAPLRDIHGAHRIANFFVKVATQPWQGYRPEQWEFAAAQINGANGVLIRVEGKVVTAFTTEVLDGRITAIHLVGNPDKLAHLDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZB2</accession>
    <name>D3PZB2_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PhoD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017157.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1890"/>
    <dbReference type="EnsemblBacteria" id="ADD41586">
        <property type="protein sequence ID" value="ADD41586"/>
        <property type="gene ID" value="Snas_1890"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1890"/>
    <dbReference type="eggNOG" id="COG3540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_512549_0_0_11"/>
    <dbReference type="OMA" id="VYQHLGN"/>
    <dbReference type="OrthoDB" id="165142at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD" evidence="1">
        <location>
            <begin position="126"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="535" mass="60475" checksum="2384D526F0FEACB6" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZP5</accession>
    <name>D3PZP5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3927</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019153.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3927"/>
    <dbReference type="EnsemblBacteria" id="ADD43582">
        <property type="protein sequence ID" value="ADD43582"/>
        <property type="gene ID" value="Snas_3927"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3927"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_3_1_11"/>
    <dbReference type="OMA" id="HARDHRA"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003012">
        <property type="entry name" value="Tet_transcr_reg_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00400">
        <property type="entry name" value="TETREPRESSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="6">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="23571" checksum="76A2731037751C62" modified="2010-04-20" version="1">MAGRTQGQRAGLTRQAILDAALRLADREGLKALSMRRLGAELGVEAMTLYHHIPNKDALLDGLVEQVVTLAEAPRFGQARWPDVLRDYARSLLDTLLAHPAVLPLVATRPATTPANLRMVEATLEALCRDGFTPDEALAVVYSMTGFVVGQATALAQAAHDDAQHTRGQLEQLSALDESEYPLLARAAREAGAARSRFDFALDAMLTGFDVALRREGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZR9</accession>
    <name>D3PZR9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3954</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019177.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3954"/>
    <dbReference type="CAZy" id="GH16">
        <property type="family name" value="Glycoside Hydrolase Family 16"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43606">
        <property type="protein sequence ID" value="ADD43606"/>
        <property type="gene ID" value="Snas_3954"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3954"/>
    <dbReference type="eggNOG" id="COG2273">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019533_3_0_11"/>
    <dbReference type="OMA" id="FDVMENV"/>
    <dbReference type="OrthoDB" id="1046649at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048501" evidence="1">
        <location>
            <begin position="40"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="34"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="318" mass="34148" checksum="DCDD24568DE8608A" modified="2010-04-20" version="1">MRHDSSPSATKPTKRRLLTAAAVLLLSAALLAVPGTAQASIPTNPGWTQVFGDDFDGAAGSLPSTDRWRFSIGHGYPGGPANWGTGEIAYHTDDPNNVSVDGNGNLNITPRRDGSGNWTSARIETNKQDFKPPSGGVVRIESRLQMPNVTGEAAKGYWPAFWALGSPYRGNWWNWPGIGEFDVMENVNGIDSVWGVLHCGTAPGGPCNENNGIGASRPCPGGTCQSGFHTYTFEWDTSVSPHQLRWLVDGQQFHSVRQDQLPADTWNQMTSHAGYFIILNVAIGGAFPDGVAGHQTPTAATVPNHPMVVDYVAVWTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZX9</accession>
    <name>D3PZX9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospho-N-acetylmuramoyl-pentapeptide-transferase</fullName>
            <ecNumber evidence="7">2.7.8.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-pentapeptide phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraY</name>
        <name evidence="8" type="ordered locus">Snas_4014</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP</text>
            <dbReference type="Rhea" id="RHEA:28386"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="EC" id="2.7.8.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.13" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019237.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4014"/>
    <dbReference type="EnsemblBacteria" id="ADD43666">
        <property type="protein sequence ID" value="ADD43666"/>
        <property type="gene ID" value="Snas_4014"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4014"/>
    <dbReference type="eggNOG" id="COG0472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023982_0_1_11"/>
    <dbReference type="OMA" id="LMSPLHH"/>
    <dbReference type="OrthoDB" id="1151822at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051992">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00038">
        <property type="entry name" value="MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10555">
        <property type="entry name" value="MraY_sig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01347">
        <property type="entry name" value="MRAY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD43666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="365" mass="39241" checksum="59BE557636C448DD" modified="2010-04-20" version="1">MRSVIVAAFVAFAISLFFTPLAVKGFRRLKADQPIRTDGPQTHLGKKGTPTMGGVVFIVATVIAYVAGHGVLMVMPEGYERPQGFTATGIVLLGLFVCLGLVGFIDDFLKVRRKNSGGLNKRGKLIGQIVVAAGFGWLALYYTGSIGKTVASDRLSFVRDIDWLQLSKIGAVIMFVLVVMATSNGVNLTDGLDGLATGASIMALSAYVMIAFWQYRHWCLGPEKLTDYCYDVRDPLEIALIAGAAAGACFGFLWWNTSPAQIFMGDTGALGLGGLIGGLALATKTIMLLPILGALFVIITFSVIIQITSFKMTGRRVFRMAPLQHHFELAGWSEVNIVVRFWIIAGIGVAIGLGLFYADFLKVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZY8</accession>
    <name>D3PZY8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF3817 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_4023</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019246.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4023"/>
    <dbReference type="EnsemblBacteria" id="ADD43675">
        <property type="protein sequence ID" value="ADD43675"/>
        <property type="gene ID" value="Snas_4023"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4023"/>
    <dbReference type="eggNOG" id="ENOG5030J66">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120964_1_3_11"/>
    <dbReference type="OMA" id="TRYRVMA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023845">
        <property type="entry name" value="DUF3817_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12823">
        <property type="entry name" value="DUF3817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03954">
        <property type="entry name" value="integ_memb_HG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3817" evidence="8">
        <location>
            <begin position="11"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD43675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="116" mass="12976" checksum="ABB6756C02CD4197" modified="2010-04-20" version="1">MDAKPEIGAALRRYQVTAWIVSVFLVALFFVAMPVRYIGGEPVLSAIISPIHGFGYMVYLAFAFDLARRMGWSLWPRTVLLLLAGTVPVVSFVTERWTTRQVLAEQEEPQVSETSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q028</accession>
    <name>D3Q028_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021128.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5930"/>
    <dbReference type="ESTHER" id="stanl-d3q028">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45557">
        <property type="protein sequence ID" value="ADD45557"/>
        <property type="gene ID" value="Snas_5930"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5930"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_43_0_11"/>
    <dbReference type="OMA" id="YEPPLKH"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="23"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="267" mass="28307" checksum="2796F5D5C066442C" modified="2010-04-20" version="1">MFTLNSPDGTEVLAAVDGRGPVILFLHAGMDSETAWARPARRLADRFRTLRVRRRRYRLDLTDEVARSLASEVDDVAALARAMDAPVLLVGHSSGAVVALEAMVAAPSSFAGAVLYEPPIVTGPPLGGEALVRARAAVAAGKPGAAIAGFVRDVVGMPGWIARAAGMYAAVSPRMRALVPRQVEELAAIDELGNRLDAYARIDSPVLLLGGERSPANLAHRLDALAAVLPHAERRTLRKLGHDGNRRSPGMLAGVIAEFADRVLNHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q033</accession>
    <name>D3Q033_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021133.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5935"/>
    <dbReference type="EnsemblBacteria" id="ADD45562">
        <property type="protein sequence ID" value="ADD45562"/>
        <property type="gene ID" value="Snas_5935"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5935"/>
    <dbReference type="eggNOG" id="COG3613">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017539_0_0_11"/>
    <dbReference type="OMA" id="TRQFSEW"/>
    <dbReference type="OrthoDB" id="690107at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="645" mass="70246" checksum="95B260055989096E" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0A4</accession>
    <name>D3Q0A4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cation diffusion facilitator family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_6007</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021204.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6007"/>
    <dbReference type="EnsemblBacteria" id="ADD45633">
        <property type="protein sequence ID" value="ADD45633"/>
        <property type="gene ID" value="Snas_6007"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6007"/>
    <dbReference type="eggNOG" id="COG0053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021126_0_1_11"/>
    <dbReference type="OMA" id="HMRTLHL"/>
    <dbReference type="OrthoDB" id="381612at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006829">
        <property type="term" value="P:zinc ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040177">
        <property type="entry name" value="SLC30A9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13414">
        <property type="entry name" value="PTHR13414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="318" mass="33776" checksum="018D7D183425CD6C" modified="2010-04-20" version="1">MSAEGGTKAIVAALAANLGIAATKLGAWALTMSSSMLAESIHSLADSGNQALLLVGGKRSKRGATAQHPFGYGRERYIYAFIVSIVLFSVGGLFALWEGQHKISDTLAGKPDTLLESQWWWVPIAVLVVAIGLETYSFYTAISESRKAKGKTSWVNFIRRAKAPELPVVLLEDAAALLGLILALFGVGLSLITGDGIWDGIFTLSIGLLLVIIAIILAIETKSLLLGESATDEHIAAIEKAILDGDDVDAIIHMKTLHLGPDELLVAAKFAVKHDETAAQVAREIDAVEARIRAAVPIARAIYLEPDLYRPAKAGGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0I0</accession>
    <name>D3Q0I0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017287.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2021"/>
    <dbReference type="EnsemblBacteria" id="ADD41716">
        <property type="protein sequence ID" value="ADD41716"/>
        <property type="gene ID" value="Snas_2021"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2021"/>
    <dbReference type="eggNOG" id="COG0177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050554_1_1_11"/>
    <dbReference type="OMA" id="EVQDVWT"/>
    <dbReference type="OrthoDB" id="1650048at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="210" mass="23071" checksum="43A85780BDE41D5F" modified="2010-04-20" version="1">MAASKDVVRGLIERHGTTYAEQAGINLRDTPAPLYQLLMLSTLLSARIGSDIAVAAAKELFTSGYRTPKAMREASWQDRVDALGRGHYRRYDEKTSTMLGDGAQLALDRWKGDLRRLHTEADDLSDVTRLLREFPGIGSTGASIFCREVQGVWTDLAPYVDERTAKGADKLGLPTDANELAKLVKPADFPRLVAGCVRVALSKNLPDDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0I3</accession>
    <name>D3Q0I3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017290.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2024"/>
    <dbReference type="EnsemblBacteria" id="ADD41719">
        <property type="protein sequence ID" value="ADD41719"/>
        <property type="gene ID" value="Snas_2024"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2024"/>
    <dbReference type="eggNOG" id="ENOG5032XDB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159908_0_0_11"/>
    <dbReference type="OMA" id="TGFEQLH"/>
    <dbReference type="OrthoDB" id="2053159at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045684">
        <property type="entry name" value="DUF6191"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19690">
        <property type="entry name" value="DUF6191"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="124" mass="13060" checksum="DC14753CDAEFE925" modified="2010-04-20" version="1">MATILFLTLPGLVLLLTVLAIVDQLLLRAGRAGMLPWRTSARQGQVASTGFEQLHAAFSLGKHEELKTRASTLVLRDDENDGAPPGSTAVDLEAGTAVMRASRPKPSTTAAAAPPYSPRPDSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0U9</accession>
    <name>D3Q0U9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)H dehydrogenase (Quinone)</fullName>
            <ecNumber evidence="2">1.6.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019270.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4047"/>
    <dbReference type="EnsemblBacteria" id="ADD43699">
        <property type="protein sequence ID" value="ADD43699"/>
        <property type="gene ID" value="Snas_4047"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4047"/>
    <dbReference type="eggNOG" id="COG2249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058643_2_1_11"/>
    <dbReference type="OMA" id="LFPIHHG"/>
    <dbReference type="OrthoDB" id="1143659at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003680">
        <property type="entry name" value="Flavodoxin_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02525">
        <property type="entry name" value="Flavodoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="256" mass="28682" checksum="DF05DF0BB343E67B" modified="2010-04-20" version="1">MKTLWIYAHPEPRSLNGSLRDEGVRTLRGLGHEVRESDLYAMNWRPVVAEDDFPGRQAGRLWVGDAQQTAYAEGTLSPDILAEQEKVLWADTIVIQFPLWWFGMPAILKGWFDRVFLQGFAFGLANPATGRQRRYGDNALSGKRALVVTTFGARESSMGPRGIHGAIDDLLFPLQHGILWYAGIAALPPLAIDGANRMSDDEYQLAAKRLRERLRNLPEQTAVPFRYQDHGDYDADLVLRPELAPGETGLSIHTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0W1</accession>
    <name>D3Q0W1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lantibiotic dehydratase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4059</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019282.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4059"/>
    <dbReference type="EnsemblBacteria" id="ADD43711">
        <property type="protein sequence ID" value="ADD43711"/>
        <property type="gene ID" value="Snas_4059"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4059"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011068_1_0_11"/>
    <dbReference type="OMA" id="LTAARWM"/>
    <dbReference type="OrthoDB" id="1406236at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006827">
        <property type="entry name" value="Lant_deHydtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04738">
        <property type="entry name" value="Lant_dehydr_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lant_dehydr_N" evidence="2">
        <location>
            <begin position="75"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="845" mass="94197" checksum="C5E69442C2864CE0" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0X7</accession>
    <name>D3Q0X7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4075</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019298.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4075"/>
    <dbReference type="EnsemblBacteria" id="ADD43727">
        <property type="protein sequence ID" value="ADD43727"/>
        <property type="gene ID" value="Snas_4075"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4075"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_11"/>
    <dbReference type="OMA" id="VTQDYRE"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD43727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="370" mass="39388" checksum="B5057F8F6CE4B28C" modified="2010-04-20" version="1">MASIDVHKVDKKFGKVTALEDVSFSVADGEFFCLLGPSGAGKTTTLKIVAGLVEPGGGTVHIDGVDVGDVEPTHRDLAMCFENYALYPQLNVFDNLASPLRSPLSRTPADEIRHRIAHTAGLLGIDHLLDRSVTQLSNGQRQRVALGRVLVRPARAYLLDEPLAHLDAKLRATMRAELKSISGGDATTTIYVTHDYVEALSLADRIGVIRDGRILQVGTPGEVWSAPANAFVAQAFGKPRINLVPGALVASDDGQTFASADGAFQVPVPSTDVGEGTEVQIGIRPRDLRLHTGAGDVPDGQVRLEGSVYVLEHLGRNTEVTVAIGQSRLSVIVPRSEVSSLARDDKVGVLMNPHTVHVFLAGAEGKRVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q127</accession>
    <name>D3Q127_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4126</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019348.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4126"/>
    <dbReference type="EnsemblBacteria" id="ADD43777">
        <property type="protein sequence ID" value="ADD43777"/>
        <property type="gene ID" value="Snas_4126"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4126"/>
    <dbReference type="eggNOG" id="ENOG5033JIV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1170096_0_0_11"/>
    <dbReference type="OMA" id="VIMKFEN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024267">
        <property type="entry name" value="DUF4878"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12870">
        <property type="entry name" value="DUF4878"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4878" evidence="3">
        <location>
            <begin position="129"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="237" mass="24951" checksum="2BFF54766C8DB462" modified="2010-04-20" version="1">MSYPPPGGQQYPDPNQQPGYGQQPGYGQQQPGYGQQQPGYGQQPGYGQQQPGYGDQQGYGQQQPGYGQQQPGYGQAQPPAGGQYGQPQGGFTPGQPPAKNKTGLIVGIAGGGVALVVVVILLVVFVFSGGGPSSAVDNVVNALEDGDYAAFKEALCEDTRKSFEELEKASGMSEEEIGKELKKNLEKEGLTADYEIVEETESGDKGTVTVKTDDGEEKIDVVVEDGEWKLCPAMPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q161</accession>
    <name>D3Q161_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6016</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6016"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45641">
        <property type="protein sequence ID" value="ADD45641"/>
        <property type="gene ID" value="Snas_6016"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6016"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_27_6_11"/>
    <dbReference type="OMA" id="VKFLDYV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="3">
        <location>
            <begin position="18"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="380" mass="40601" checksum="2DDEBB65D0ED5E60" modified="2010-04-20" version="1">MSGVKVLVDATSVPADRGGVGRYVDGLLSALAHVGDEIDLSVVCQRTDAERYLGLVPEAEVIAAPSAVTHRPARLAWEQTGLPMLAQQLGVEVLHSPFYTCPLRAGCPVTVTVHDATFFTERDHYDKARGTFFRSAIKTSLRRASRVVVPSKATRDELVRLLDVDESHVDVAYHGVDPEAFHIPAPAEKARVAARLGLAETPYVAFLGVMEPRKNVPNLVRGWVSAVRRMPAPPALVLAGGSGHDDAIDDAVAEVPVHLKVVRPGYLRFADLPGFLGGALVAAYPSYGEGFGLPILEAMACGAPVLTTPRLSLPEVGGDAVAYTGEEPDAIASDLAKLLGDEQQRSKLSILGVERARDFTWQRSASAHLATWRKAAGKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1A3</accession>
    <name>D3Q1A3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021254.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6059"/>
    <dbReference type="EnsemblBacteria" id="ADD45683">
        <property type="protein sequence ID" value="ADD45683"/>
        <property type="gene ID" value="Snas_6059"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6059"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079903_0_1_11"/>
    <dbReference type="OMA" id="ERGWTGW"/>
    <dbReference type="OrthoDB" id="1467120at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="258" mass="28923" checksum="E3D8CBB3C55B6701" modified="2010-04-20" version="1">MRSGLTIGQAAAYADVTVKAVRHYHRLGLVDEAERDSSGYRRYGSRQLLQLVRVRTLARAGIPLAQIPAMLDAGPQRFAEAIDEIDRRLAQQIAELKDRRKTLHRLESGDRALLPDRACALLERLRELDFDADTVDTYRESLILARALFPSGFDTYLARFEEAIAEPAYVDVIKRIWDAGNWEPDDPRIVGLADAAADFLLNHPTLTSLPSDLEGSDGATRYGLINHHDGQEQPPTYERLTALIEKRLRAAGVDIPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1E5</accession>
    <name>D3Q1E5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydrodipicolinate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021296.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6101"/>
    <dbReference type="EnsemblBacteria" id="ADD45725">
        <property type="protein sequence ID" value="ADD45725"/>
        <property type="gene ID" value="Snas_6101"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6101"/>
    <dbReference type="eggNOG" id="COG0329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_893997_0_0_11"/>
    <dbReference type="OMA" id="VLYNPPH"/>
    <dbReference type="OrthoDB" id="1438588at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="317" mass="33971" checksum="4F9AA0520D1B7BD7" modified="2010-04-20" version="1">MQAFTASDLYGVWATALLPVTDTETIDFERLESALDVLLDSGVHGLYTNGSAGEFHTLTEMEYDRLHELFAARCRDAGMPFQLGASHPSGQLSLARIRRATTFRPGAIQVILPDWLPLRPDEVIAAVARMADAADGVPLVLYNPPCAKTRLDPELFGRLAEAVPTLIGVKVPGGDAAWFARMRDGAARRLAIFVAGHTLAAKLPLGASGSYSNVACLSPAGAVRWYQRMLADPQSALDTQKRLLTFFDEHIAPLGARGYSDPALDKTLAAIGDWAPIGTRVRWPYASVPAELVPGLRDAAHRAVPELFSGATIASGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1M4</accession>
    <name>D3Q1M4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0152</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015443.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0152"/>
    <dbReference type="EnsemblBacteria" id="ADD39872">
        <property type="protein sequence ID" value="ADD39872"/>
        <property type="gene ID" value="Snas_0152"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0152"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_11"/>
    <dbReference type="OMA" id="VCMSKLR"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="123"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="123"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD39872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="218" mass="23472" checksum="774A627EC7680C54" modified="2010-04-20" version="1">MRVLLVEDEEPLAGYIAVGLRKHGLAVDVAHDGQTALDKCDFTPYDVVVLDRDLPVVHGDTVCQRLAAQGTARVLMLTASGTVEDRVDGLSLGADDYLGKPFAFSELIARVRALARRSAPARPPLLRAADVVCDPARRTVERAGRPIHLTPKEFGVLEQLLAAGGDVVSAETLLDKVWDEHADPFSNAPRITVGTLRRKLGEPPLIQTVTGAGYRVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1Q7</accession>
    <name>D3Q1Q7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015476.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0186"/>
    <dbReference type="EnsemblBacteria" id="ADD39905">
        <property type="protein sequence ID" value="ADD39905"/>
        <property type="gene ID" value="Snas_0186"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0186"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_1_11"/>
    <dbReference type="OMA" id="AHYPNME"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="14"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD39905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="258" mass="28200" checksum="4D791F3577D3090E" modified="2010-04-20" version="1">MSDLFRYETGSGRPLVFLHGGFLDHHMWDDQLPGFGEDHRVIAPDARGHGRSPNATGPFRHTDDVARLLRHLDTGPAILIGVSMGGATAVDTALEHPELVAALVVSGVGTSEPYFTDPWTTDTWTRWHTAMTAGDIDTSIQVFTEFAAGPHRGLDDIDGSVADRLRHMTRSTMSKHTADEPDWQTPVPDTWSRVADITVPVLAVNGAIDSPDHLGMAERLTTTVRDGRSTAIDGTAHYPNMEEPARFNAIVREFITTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1Z6</accession>
    <name>D3Q1Z6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2171</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017434.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2171"/>
    <dbReference type="EnsemblBacteria" id="ADD41863">
        <property type="protein sequence ID" value="ADD41863"/>
        <property type="gene ID" value="Snas_2171"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2171"/>
    <dbReference type="HOGENOM" id="CLU_1093765_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="254" mass="27288" checksum="E8388AA9871EA3B8" modified="2010-04-20" version="1">MTQPFQYDPSQQPGQPSAPFDPAQQGQPAAPFDQPPQQPPYDPGAQQPSPLTFEPGQAAAQPFGPSSEPPVFLPPQADFLPDGPKKSRGGLYVVLAIVVVLLIGGGIGVAIWRPWAPATGTTDKADSSEDAKDEGKDEGKDDDKKGEESDSDKGVPSQVVDDAWHAKDWDQAKSYMCEKLVTKLEKNGAADKYKPIGADEEFKTTDEKIDGEKATVSVETSAKSSSGKTELASFKVNLVKEESDWKICEISEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q246</accession>
    <name>D3Q246_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017484.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2223"/>
    <dbReference type="EnsemblBacteria" id="ADD41913">
        <property type="protein sequence ID" value="ADD41913"/>
        <property type="gene ID" value="Snas_2223"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2223"/>
    <dbReference type="eggNOG" id="ENOG5032TA6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118603_0_0_11"/>
    <dbReference type="OMA" id="WGWIHLA"/>
    <dbReference type="OrthoDB" id="1854263at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="142" mass="15400" checksum="27905F59E883EADE" modified="2010-04-20" version="1">MTREQHGTVPQPGTRVARGEGLRLFAAAIMIMIGMFHLIAGFAAVLRGSYFVVSENYFLVIDVAVWGWGHLVLGIIVVATGAALFAERPWAYVSGIVIVGLSALGNFMFLPYQPLWAVLIIAVDVAVVWALAMRLRELSVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q296</accession>
    <name>D3Q296_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Purine or other phosphorylase family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019400.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4179"/>
    <dbReference type="EnsemblBacteria" id="ADD43829">
        <property type="protein sequence ID" value="ADD43829"/>
        <property type="gene ID" value="Snas_4179"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4179"/>
    <dbReference type="eggNOG" id="COG0775">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_789651_0_0_11"/>
    <dbReference type="OMA" id="YAYHGGT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="1">
        <location>
            <begin position="11"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="351" mass="37533" checksum="23EB8051649647DA" modified="2010-04-20" version="1">MPTDNHRPVAVVCAALGLEYQAILEHLETPPIEHDERGSLYQLGDFEHWCVVATHIGRDNTPAAVQVERAITLFQPAVVLLVGIAGGRRKVRHGDVVAADSVYDYQAGRDTGETTLGRVKSLSASFPLVQRAKAVASQNRWRDRIVLPLDRPPEAHVGPLAAGGRVVTSAESHTALLIERHCDDALGIETEGFGVMAAAHANPSVSAMVIRGISDLLDDKAFAADRHWQPVAARHACAFAFELLHHTRPDQPAAHTAPGEQRPASTYIVAQGDNAVANVAAVGDHSRGELHIHRLTTQPHVAAAVRILAARRRSGGPGRDCQRHGLSVPAPGGEACRTVLTPKGYGSRHVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2C5</accession>
    <name>D3Q2C5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019429.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4209"/>
    <dbReference type="EnsemblBacteria" id="ADD43858">
        <property type="protein sequence ID" value="ADD43858"/>
        <property type="gene ID" value="Snas_4209"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4209"/>
    <dbReference type="eggNOG" id="ENOG503437N">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2107519_0_0_11"/>
    <dbReference type="OrthoDB" id="2193234at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="115" mass="12477" checksum="C1C0EFCDB504CDEF" modified="2010-04-20" version="1">MPTVVPPTQNPPTDPAPVALDDCGALVSSLRHAEAMAAQWSDAAAELRRVLIERLGDAELGTINGHPAVRHTTYRDTRVSTKMLRELAPADLIERCTTTTTRRRFTLVDTDSGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2L8</accession>
    <name>D3Q2L8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase III subunit gamma/tau</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dnaX</name>
        <name evidence="7" type="ordered locus">Snas_6146</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DnaX/STICHEL family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021340.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6146"/>
    <dbReference type="EnsemblBacteria" id="ADD45769">
        <property type="protein sequence ID" value="ADD45769"/>
        <property type="gene ID" value="Snas_6146"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6146"/>
    <dbReference type="eggNOG" id="COG2812">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006229_3_1_11"/>
    <dbReference type="OMA" id="PGHIVSH"/>
    <dbReference type="OrthoDB" id="556582at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18137">
        <property type="entry name" value="HLD_clamp_pol_III_gamma_tau"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022754">
        <property type="entry name" value="DNA_pol_III_gamma-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012763">
        <property type="entry name" value="DNA_pol_III_sug/sutau_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045085">
        <property type="entry name" value="HLD_clamp_pol_III_gamma_tau"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12169">
        <property type="entry name" value="DNA_pol3_gamma3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02397">
        <property type="entry name" value="dnaX_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA" evidence="6">
        <location>
            <begin position="36"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="404"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="610"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="612"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="690" mass="70844" checksum="C9197DCE09D578B4" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2W4</accession>
    <name>D3Q2W4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6244</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6244"/>
    <dbReference type="EnsemblBacteria" id="ADD45865">
        <property type="protein sequence ID" value="ADD45865"/>
        <property type="gene ID" value="Snas_6244"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6244"/>
    <dbReference type="eggNOG" id="COG5606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052958_0_0_11"/>
    <dbReference type="OMA" id="AFDLGHW"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="418" mass="45396" checksum="38D3870100E7E92A" modified="2010-04-20" version="1">MDPIDPWTGDGLCHLQELVNLPNERFAARVRVSTRTIANWRKQKRQILPRLAQRSLTELLDELPEPLQQKFRQAVQRGVPTPETTVSDLVTVASEDALLDVQRYSLDSASEVLETLSEDSAAIARGSRRTARQAFRAAQSVADQARQLIEKTHRPSLLSDLYVVVGQTNALMASSAFDLGHWDAADHIARAAAIYASMAGHSSLEAWVLGLQASMANWREEPDTALALLRKAQTIAPSGEPSVRVKYIAARSYALVGDIYGIQDTLQSAQDDVDRASSNKDPLSHYTGGEFAFGAARAAACAAAAWLDVGEGTQVVHQANAALEEMQALPAGRQSLSQISGTRIDLAAGRLLSRDRDGALEALRPVLSVPTSARNISLTGRLTRVKDILQSELWRSDAEAQEVADEVQDWLTTSSVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Y2</accession>
    <name>D3Q2Y2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0233"/>
    <dbReference type="EnsemblBacteria" id="ADD39952">
        <property type="protein sequence ID" value="ADD39952"/>
        <property type="gene ID" value="Snas_0233"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0233"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_560090_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="487" mass="50392" checksum="69E87169EF9F5D84" modified="2010-04-20" version="1">MSKSTPVNAIGTAFAVAVLAALAQLGLATGLAILIWRSGSAAEWAAQLSWGAFLAAVATIAGGLVAGRLITDTGPRITAVLASGIGAFTLAPLIAVPAMRFEDAPIATAPFAAVGIGVLAGLLLSGLALAWRAIKISVLATIALTWVLAILAAFVPVDDASRIVKVAVWGEWKGLSASAPIVPALLVGTLLIGMITAWVMTSPDAVGDHRITAISGAVGPLLLVAAYAAAGQDDVRVDPQWHGMGVGTGAVVAGLLGGLLVTALRRAPSPAPAVDTALTPTATATASVEPGSLGDPSEDDRTQTVPAMPRADQTYEVPAAPPPFPPPPAENLDPYVSAEYDEAQLTQYVDATAAAGHQAEVRGTEFDEPEPPPPPPAPEPEPQPEPAKKTAKKARKTAKPKPKPEPAPEPEAEQALFPPPEPESDPGKTKAMPAAKPDETDPDENWYSELRDENAFINDHNETPDSAPEPEAAPQKKRRWGRKKKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q350</accession>
    <name>D3Q350_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015591.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0302"/>
    <dbReference type="EnsemblBacteria" id="ADD40020">
        <property type="protein sequence ID" value="ADD40020"/>
        <property type="gene ID" value="Snas_0302"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0302"/>
    <dbReference type="eggNOG" id="ENOG5031GJC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030181_0_0_11"/>
    <dbReference type="OMA" id="GRFWSYC"/>
    <dbReference type="OrthoDB" id="2064731at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025447">
        <property type="entry name" value="DUF4192"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13830">
        <property type="entry name" value="DUF4192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="343" mass="36945" checksum="C7915A7F62FFF5A9" modified="2010-04-20" version="1">MTPSCEPPTEPDAADISLSTPMDLLSAIPYLVGYIPADSLVLVGLDAKQITATLRVDLPRTDQPVTKLRISPDVLRRNKVEAAVIAGYGPPERVTRCVDHLRRMLAAQNIELVDALRVTDGTFWSYVCQEPACCPPEGRPVNPGDSPVDAAFTYAGMRALPHRQAVTAQLEPVKGPTRAAVTRATNQVRKLLDDTDAMFSARETLLDEARTILAKATEAGAPLPEIDQTVRLAAALTDAKLQTEAMTLVDSHSPHKMVDLWLWVTRHVAPAFRARPAALLGFAAWRCGNGVLATEAVRRSLTDDPHCPLAMVLGRLLDEGVPPSSIPKITGELLLPLPCSPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3F0</accession>
    <name>D3Q3F0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2302"/>
    <dbReference type="EnsemblBacteria" id="ADD41991">
        <property type="protein sequence ID" value="ADD41991"/>
        <property type="gene ID" value="Snas_2302"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2302"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_15_1_11"/>
    <dbReference type="OMA" id="MRISQIA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="127" mass="13909" checksum="C6C14B0D3B54372B" modified="2010-04-20" version="1">MRRLPRDMSLTSAATLATLDKTGPRRITDLAVAEGVTQPAMTVLVRVMEESGLVERTTDPSDKRVTLVCLTEAGASYVRTRRQAGVDAYARLIDELTGDEVKTLEAALPALLRLAELESPTRDEPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3J4</accession>
    <name>D3Q3J4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2349</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017606.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2349"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42035">
        <property type="protein sequence ID" value="ADD42035"/>
        <property type="gene ID" value="Snas_2349"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2349"/>
    <dbReference type="eggNOG" id="COG0297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_3_11"/>
    <dbReference type="OMA" id="WEFPPRI"/>
    <dbReference type="OrthoDB" id="694191at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="11"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="206"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="414" mass="44918" checksum="D740F05C113E7DE9" modified="2010-04-20" version="1">MLSWEYPPVLVGGLGRSVHALATALAAEGHDVTVATRHGDHPDGSAAAFDETVDGVRVVRAPQDPPLFPFTGETLLEWTMAFNHSLTRTALRACRTQDFDVIHAHDWLVTHAAVTLKHHLDLPLVATIHSTEAGRHHGWLPDDTSRAIHSIEWWLTYESRRVLVCSKHMRWEVNRLFELPEDKTLVVPNGVDARVFAVEDTVPDREAGPVVVSAGRLVHEKGVQDLIDAAAILREKHPGLRVLIAGEGPHEEELRDQAVRRGLEDTVEFLGFVEGAALPRLLGGADCFAIPSRYEPFGMVALEAAAAGTPVVAGRSGGLAEFIVDGETGLTHTPARPEELAEAISRVLSEPELARRLRDGGRAMVSQRFGWGPIATAVIAAYAQSEIGERAVEAELAARELRVVIPEGNLLDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3U0</accession>
    <name>D3Q3U0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid permease-associated region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_4360</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4360"/>
    <dbReference type="EnsemblBacteria" id="ADD44007">
        <property type="protein sequence ID" value="ADD44007"/>
        <property type="gene ID" value="Snas_4360"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4360"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0681">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_15_12_11"/>
    <dbReference type="OMA" id="VIAKYWG"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="526"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="577"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="602"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="635"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="659"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S24" evidence="6">
        <location>
            <begin position="25"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD44007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="686" mass="72471" checksum="9E00CCDF3ED84A0A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3U4</accession>
    <name>D3Q3U4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4364</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019582.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4364"/>
    <dbReference type="EnsemblBacteria" id="ADD44011">
        <property type="protein sequence ID" value="ADD44011"/>
        <property type="gene ID" value="Snas_4364"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4364"/>
    <dbReference type="eggNOG" id="COG0111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_0_11"/>
    <dbReference type="OMA" id="WYRYPSA"/>
    <dbReference type="OrthoDB" id="1435073at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh_C" evidence="2">
        <location>
            <begin position="102"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="305" mass="32456" checksum="A4DF5368FE733F5F" modified="2010-04-20" version="1">MKVWIPHEHGRAAMEPIPDGVELEVYDGDGDFPSSPSDVEFWVPPFMSKRVSSARLDLMPGLKVIQLLSAGADAWIAGVGESVTLCDAMGVHTAATSEWAVSAMLASLRGFDRYARNQSRRLWQPVPTDTLEGKRVLIVGAGDIGAAIATRVEAFGARPVMVARRARTGVHAVAELPQLLPDADIVVLIVPLTEATRGMVDATFLAAMPDGAMLVNAARGPVVDTAALTEEVRGGRLRAALDVTDPEPLPEDHPLWTLENVLITPHVGGAAAVPGFLDKGYALVGRQLRRYAAGEGLDNVVSEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3U8</accession>
    <name>D3Q3U8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4368</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019586.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4368"/>
    <dbReference type="EnsemblBacteria" id="ADD44015">
        <property type="protein sequence ID" value="ADD44015"/>
        <property type="gene ID" value="Snas_4368"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4368"/>
    <dbReference type="eggNOG" id="COG0613">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066403_0_0_11"/>
    <dbReference type="OMA" id="HPYVDVW"/>
    <dbReference type="OrthoDB" id="954654at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021447">
        <property type="entry name" value="DUF3097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11296">
        <property type="entry name" value="DUF3097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="271" mass="29353" checksum="773E2EC64677EC31" modified="2010-04-20" version="1">MRYGDNVLSGDWRHPKKGTVPRIEAVPGLVAEDPASGFCGAVVACGKTSVTLEDRNGKHREFRLDPAGFLIDGKPVTLVRPAPGAAGPRRSASGSTRVEGLRAKVAKQSRIYVEGVHDAALVERIWGHDLRVEGVVVEYLEGVDDLPAIVAEFGPEPGRRLGVLVDHLVAGSKESRIAEQITSPHVLVVGHPFVDIWQAVKPARLGFEAWPDVPRGVPWKEGVIAALGWRLSPPEAWRRILGAVDSYADLEPELLGRVEELIDFVTEPGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3X7</accession>
    <name>D3Q3X7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019615.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4398"/>
    <dbReference type="EnsemblBacteria" id="ADD44044">
        <property type="protein sequence ID" value="ADD44044"/>
        <property type="gene ID" value="Snas_4398"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4398"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070294_0_0_11"/>
    <dbReference type="OMA" id="VHAVMAI"/>
    <dbReference type="OrthoDB" id="1755236at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="290" mass="29898" checksum="09F16317CC70EA05" modified="2010-04-20" version="1">MSAAWLGVLIAFVGAFSYALGAAIQQLDAVKLGANRALLKQPRWWIGGAISFLGACLHAVALIMAPLTIIQPISMTTLVYAVPLAAKLHGRKPRRAELLGSVAVSIGLAGLMAMIPLSDNKTPTLDSGPAIGFLVGVLAFVAVTQFIGSRATGPHRALFYALGAGVATGTVSTFVRLVGAGASEDFAQLFHWFSLVVPSMLILATILLQRAYAIGYFGIAYAVAQVSDPVASVLAGAGLLGEPLPTNPSLFVPALLCGALLIAGTIVLGRNAPDTGHVKEPVPELVRTGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3Z7</accession>
    <name>D3Q3Z7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021453.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6262"/>
    <dbReference type="EnsemblBacteria" id="ADD45882">
        <property type="protein sequence ID" value="ADD45882"/>
        <property type="gene ID" value="Snas_6262"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6262"/>
    <dbReference type="HOGENOM" id="CLU_2411761_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="92" mass="10470" checksum="1CF7AB3D61202796" modified="2010-04-20" version="1">MPELRVRIDGADVALGECEWVLWAPCGCPIGCALASEGNRATEELAWKGFYPNQRDIDDHKKSGFRLELMTRQHWSAEVYPLMLQHDCPHTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q417</accession>
    <name>D3Q417_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6282"/>
    <dbReference type="EnsemblBacteria" id="ADD45902">
        <property type="protein sequence ID" value="ADD45902"/>
        <property type="gene ID" value="Snas_6282"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6282"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_2_3_11"/>
    <dbReference type="OMA" id="EQQAHIF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048643" evidence="1">
        <location>
            <begin position="27"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="433" mass="47069" checksum="FF2B0E1F1F55957A" modified="2010-04-20" version="1">MRVSRHRGRVAALTALAAVAVSGLTACSGDDRIKLTVQVFGGAGFGYEDLVKEYEKDHPDIDVDYQIVTDDYDNEFRPQVLQWLEAGSGAGDVVGIEEQGVGQMMSLGDAWADLSEYGLDKRESDYPSWKWEQGHTADGKLAGLGTDVGGMAMCYRTDLFKKAGLPTDREKVAELWQDWDGFTKAAKKFTDSDVDAAFVDSPNQLYNIRMVQEAGAADGISYFDRKDKYVAGDTEAVRTAFDYVAELHELGAVGQFENWSDEWNSAMQAGGFATMGCPAWMMGVIADTSGKENKGNWDVAQVPGGSGNWGGSWLGVPAQSDHPKEAAELADYLTKPKSQVAAFEAISAFPSTKEGQEDPKVADLSNEYFNDAPTGKLIADSVKEFKPVYYGELHSAVRAAVEDVLFGLVQGSYKHDEAWKEFVAAGQEVVDTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q498</accession>
    <name>D3Q498_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase/phosphodiesterase with GAF sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6367</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6367"/>
    <dbReference type="EnsemblBacteria" id="ADD45983">
        <property type="protein sequence ID" value="ADD45983"/>
        <property type="gene ID" value="Snas_6367"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6367"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_49_11"/>
    <dbReference type="OMA" id="MQAEYAT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="436"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="576"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="840" mass="91294" checksum="011262A2AE7E9507" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4K0</accession>
    <name>D3Q4K0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Threonine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0445</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the threonine synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015731.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0445"/>
    <dbReference type="EnsemblBacteria" id="ADD40160">
        <property type="protein sequence ID" value="ADD40160"/>
        <property type="gene ID" value="Snas_0445"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0445"/>
    <dbReference type="eggNOG" id="COG0498">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028142_4_1_11"/>
    <dbReference type="OMA" id="DDVNRFC"/>
    <dbReference type="OrthoDB" id="428821at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901607">
        <property type="term" value="P:alpha-amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="6">
        <location>
            <begin position="81"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604450-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="418" mass="44125" checksum="CE7B6C17BCF16752" modified="2010-04-20" version="1">MTTTSVFTDSPAVGLVCRGCSATYPLAAQHACWECFGPLEVDYDATALAKVTREQIESGPDNIWRYAALLPAGVDAATRVTLNPGMTPLVKADNLAAELGMKALWVKDDSANPTHSFKDRVVSVALTAASQLGFDRFACASTGNLANSVAAHAARAGKPSIVFIPYDLEPGKVITTAVYGGQLVAIEGSYDDVNRLCSELTETDEFENTAFVNVNVRPFYAEGSKTLGYEVAEQLGWRLPRQVVIPMASGELLTKVDKAFTEMGEIGLVDPSEVKVFGAQSSGCNPIATALRAGTDEITPVKPTGIAKSLNIGDPAAGPYAIESVRRTGGWMADVDDDEIREGIRLLARTTGVFAETAGGVVVATLKKLLAEGRLDPEAETVIYNTGEGLKTLDAVTAGPTHQVKPSLKSVKEAGLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4X7</accession>
    <name>D3Q4X7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DEAD/DEAH box helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_2474</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2474"/>
    <dbReference type="EnsemblBacteria" id="ADD42157">
        <property type="protein sequence ID" value="ADD42157"/>
        <property type="gene ID" value="Snas_2474"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2474"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_27_1_11"/>
    <dbReference type="OMA" id="EYCTPIQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="9">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="49"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="250"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="432"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="432"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="487"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD42157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="544" mass="58527" checksum="4427DDE37C8B8814" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5J2</accession>
    <name>D3Q5J2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polynucleotide adenylyltransferase/metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_6436</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021623.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6436"/>
    <dbReference type="EnsemblBacteria" id="ADD46052">
        <property type="protein sequence ID" value="ADD46052"/>
        <property type="gene ID" value="Snas_6436"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6436"/>
    <dbReference type="eggNOG" id="COG0617">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015961_6_1_11"/>
    <dbReference type="OMA" id="HRHKDVY"/>
    <dbReference type="OrthoDB" id="2018439at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014065">
        <property type="entry name" value="tRNA_adenylyltransferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02692">
        <property type="entry name" value="tRNA_CCA_actino"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="3">
        <location>
            <begin position="255"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD46052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="473" mass="52350" checksum="4D21A495049E7602" modified="2010-04-20" version="1">MSDRIGNEISVPPVADALGEVFAAAGHELHLVGGPVRDAILRRDTVDLDFATSAHPEVTQAILEEHSSTIWTTGREFGTIGAMFRGHRVEVTTFRADTYDGVSRNPQVAYGDNLTDDLRRRDFTINAMAVSVPGHEFSDPFGGLTDLAQQTIRTPGTPEDSFADDPLRMMRAARFTSQLGFHVDPAVKTAMTNMARDIERISAERVRDEFVKLMGGTDPVPGLRLLVATGLAEEFLPELPALRMAIDEHAQHKDVYEHTLTVVRNAMSLEEDGPDVLLRIAALLHDIGKPETKGIGPDGRVTFHHHEVAGARIARKRLKALKFPKDDIGAICHLIALHLRFYGYGRGEWTDSAVRRYVTDAGAVLPRLHKLVRSDCTTRNKRKAARLAADYDALEERISRIAAEEDLAKVRPDLNGEEIMTLLEIKPGPQVGKAWKHLKELRLEQGPLSREEAETALFAWAREQGIAVPGSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5N5</accession>
    <name>D3Q5N5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ParB-like partition protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6480</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD46095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021666.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6480"/>
    <dbReference type="EnsemblBacteria" id="ADD46095">
        <property type="protein sequence ID" value="ADD46095"/>
        <property type="gene ID" value="Snas_6480"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6480"/>
    <dbReference type="eggNOG" id="COG1475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023853_0_0_11"/>
    <dbReference type="OMA" id="IALSYQR"/>
    <dbReference type="OrthoDB" id="653368at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041468">
        <property type="entry name" value="HTH_ParB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17762">
        <property type="entry name" value="HTH_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="4">
        <location>
            <begin position="84"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="280"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD46095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="358" mass="38719" checksum="E059206263CAAB0B" modified="2010-04-20" version="1">MRKKGGLGKGLAALIPSEKQEAPAEETATVSRETAPVAETVPEPRAGDAAAATAEPTAPPSDVSRETADATDPDLVPVPGAVYRLVPLAEIDTNPKQPRQVFDEEGIEELKVSLSEVGLLQPIAVRETGDGYELIVGERRTRAARELGWETIPAIVRETRDEDLLRDALLENIHRVQLNPLEEGAAYQQLLDEFGVTQEELSKRIGRSRPQISNTIRLLSLPPAVQRRVAAGVLSAGHARAILTLPTDEKREALATRIVAEGMSVRATEEAVSMELAKLDPEEPADVSRETKPKRNGALRAPGIADLTDRLSDHFDTKVKVSLGQRKGRIVIEFGSVGDLERITSSMGLETKRAEPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5P5</accession>
    <name>D3Q5P5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Silent information regulator protein Sir2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0479</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015765.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0479"/>
    <dbReference type="EnsemblBacteria" id="ADD40194">
        <property type="protein sequence ID" value="ADD40194"/>
        <property type="gene ID" value="Snas_0479"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0479"/>
    <dbReference type="eggNOG" id="COG0846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023643_3_1_11"/>
    <dbReference type="OMA" id="SMQVYPA"/>
    <dbReference type="OrthoDB" id="1264438at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="248" mass="25936" checksum="8349F5A8890F40BA" modified="2010-04-20" version="1">MDEVSLSELAPLKEYSRVVVLTGAGISRPSGLPTYRGDDGTWNDPEAARAAEADTVGTDLAAVWRLWGGLAHLAAAAQPNPAHRALAGAEESLLARTASLLVVTQNVDGLHQRGGQRDVIELHGNAHRQRCLDAGCALVAPYVGTGETIPSCAGCGGRARPDIVLFGEQLDLEDLERAWNTAAEADLLLAVGTSCGVSPAANLVAVARQAGALCVALTREPLPFNPGFHAAVTGLAERELPRWVAETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5R8</accession>
    <name>D3Q5R8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CBS domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0502"/>
    <dbReference type="EnsemblBacteria" id="ADD40217">
        <property type="protein sequence ID" value="ADD40217"/>
        <property type="gene ID" value="Snas_0502"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0502"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116232_0_0_11"/>
    <dbReference type="OMA" id="MADRCAE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="1">
        <location>
            <begin position="110"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="159" mass="16337" checksum="D270FA8696A34FDE" modified="2010-04-20" version="1">MGQTGDGAILECMHAGALAKDFPTVTLDTSALEAAKLMAGNDLPGLIVLGSNGCPYTVLGGTQVLRMSVPLYIQDDPTLAGVVDEAAADTFVAGLGNKTVRELLPEEPFDLPVVGARATLLEVAALMARVRIPVVAVVDNDTLLGAITVDSLLDHALGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q5W0</accession>
    <name>D3Q5W0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_0545</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015830.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0545"/>
    <dbReference type="EnsemblBacteria" id="ADD40259">
        <property type="protein sequence ID" value="ADD40259"/>
        <property type="gene ID" value="Snas_0545"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0545"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_1_11"/>
    <dbReference type="OMA" id="FYRYATE"/>
    <dbReference type="OrthoDB" id="816674at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="408" mass="45163" checksum="C5DDBF2CB3670759" modified="2010-04-20" version="1">MNQMGDVPRGLPVERDAGPFDPPSGLTRLRETRPVSPLVFPSGHEGWVVTGYEAVRQLMADTRFSSRQDIGVVHDLIPMEGLEVPTDPGPQQPGLFIAMDPPDHGRIRGKLTGTFTVKRMKTLEEGIVAIVERQLDHLASLTPPVDLVAEFALPVPSLVICEMLGVPYEDRETFQVNTNTFLNTDVTFEEKMAALTELTTYLAGLVTGKRAQPDDDILSDLARDEDLTIEELVGIGFLLLLAGHETTANMLGLGTFALLEHPEQLAELRQNPELMPNAVEELMRYLSIADNFYRYAIEDIEFGGETIPEGSTVVVSLLAANRDPKKFENPDLLDINRKARGHMSFGHGVHQCLGQQLARIEMRAGFNGLLRRIPSLKLAIPADEVKLRTNMRIYGVHELPVTWTETAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q633</accession>
    <name>D3Q633_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017779.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2527"/>
    <dbReference type="EnsemblBacteria" id="ADD42208">
        <property type="protein sequence ID" value="ADD42208"/>
        <property type="gene ID" value="Snas_2527"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2527"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_5_11"/>
    <dbReference type="OMA" id="YKHMVGH"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="4"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="388" mass="41007" checksum="BF5222476C1BB507" modified="2010-04-20" version="1">MRNAVIVGGGIGGLTAALALRGHGWQVAVYERSRSLEPVGSGLAVAPNALRALDTIGVGAEVRRLSSFAGAGGLRRSSGGWLNRVSVERLTEHFGDPTVVLPRAALVEQLSSRIDPAELHLGVQVEAVDPETGIVTTDEGVVSADLVVAADGIGSRLRATVFPDHPRPVYSGGTTWRVIVPAPAKRPEPAEYWGRGSAVGVVPLADGRVYLYAMARCAPGERAPDDERAELLRRFGSWAAPIPELFASADPARVLRNDVYFMETPLPALHGGRVAILGDAAHAMTPNLGQGACMAIEDAVTLAHEVTKGDGLAGYTRSRSARTSMMVAESAKVGRIAMLDNPFAVAARDTGMWLAGRLGTGPALRKAAQYYDWWPPREPSVTADESRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q673</accession>
    <name>D3Q673_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2568</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017819.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2568"/>
    <dbReference type="EnsemblBacteria" id="ADD42248">
        <property type="protein sequence ID" value="ADD42248"/>
        <property type="gene ID" value="Snas_2568"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2568"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2083417_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="117" mass="12739" checksum="75BFFEF2A9312517" modified="2010-04-20" version="1">MSAGWRPVDEWLPELANRQVLKDPDGALDDTVPAKRPISVRVLDPLGMKDTGFHVPAGKMDRFPPLYAPDSQTGEFKVEDEAEGGHLAYGLGQHGGWGFGMAVRTFRGDYAPLGQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6H3</accession>
    <name>D3Q6H3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4572</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019787.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4572"/>
    <dbReference type="EnsemblBacteria" id="ADD44216">
        <property type="protein sequence ID" value="ADD44216"/>
        <property type="gene ID" value="Snas_4572"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4572"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="RMDICEI"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="133"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="200" mass="21008" checksum="B7A180A7A19F9ED0" modified="2010-04-20" version="1">MIKVLLADDQALVRGAMAAMLGLETDIEVVAEVGTGDEVLPAVARLRPDVALLDVQMPGDGLSVAARLRDEHPTVRVIICTTFGRPGYLARATRAGAAGFVVKDTPPEQLVESIRRVHAGLRVIDPALAAESSVLGTSPLTERERQVLSAIAGGGTIADAARRLFLSQGTVRNHLSSAIGKTGTRTSAEAARLADDRGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6H4</accession>
    <name>D3Q6H4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4573</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4573"/>
    <dbReference type="EnsemblBacteria" id="ADD44217">
        <property type="protein sequence ID" value="ADD44217"/>
        <property type="gene ID" value="Snas_4573"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4573"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_8_11"/>
    <dbReference type="OMA" id="QVRIEHT"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="209"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="396" mass="42360" checksum="CEBEBA7480E8478E" modified="2010-04-20" version="1">MAATTGTGLRCAAVRELQLARFRVPSWAAIDRLPGSSASRTIRFLAVVGGLTVVCAWVSAYTVPEPGTGMPRSVGVALWVVYTVSLLVLPVRLWRSTLWQRLAMNLWLNLLGVAILFAFWFTDILVFLFSIAVAAVTLPMLMAVSLNGVVLGAMFALSVTVADKEMSGADMAVLISIAISATVTGQLIRTVNQLRETRAELARLAVVNERNRLARDLHDVLGHSLTTISVKAGLARRLLESGTDDRARLVAEVSDSERLARQAMTEVRAVVSEYRTSLRTELAGVAEALDAAGIRAVLPSVVDVVPGEWQPAFAYVLREGVTNVMRHSRASVCEVRVGPNWIEVVDDGRGSSDGKPGNGITGLRERLAVVGGTVTAGPRPDGEGFRLRAVVPGGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6K1</accession>
    <name>D3Q6K1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4600"/>
    <dbReference type="EnsemblBacteria" id="ADD44244">
        <property type="protein sequence ID" value="ADD44244"/>
        <property type="gene ID" value="Snas_4600"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4600"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_2_0_11"/>
    <dbReference type="OMA" id="YSEPILC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="48"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="304" mass="32801" checksum="4FF7FEA27CC355E4" modified="2010-04-20" version="1">MTAQPRWSRRDLFRGGLLAGGLALAPGLLTGCSLVGGDSIKKIEAGDPITLGMSNEPPFAYKDDNGKVIGESVAIYTHILKKLGAEDGQIETKIVDWNSLIPGLRADDYDLISAGMFINKLRCERAIFSEPDYICKTALLVKKGNPHNLKDFGSFKKGDNRVGLVTAGAELALAEAAGVPKKNMKQLPNNNDLKSALHADQIAAIALTSPAMNYMADTSNGAFETVKPPFGPKDENGEEQIAGAGGAVFRDDDTNFRDAVNEELAKIKTSVDSWLKITGEFGFTKYEYPDPKNPKYTTAELCKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6K5</accession>
    <name>D3Q6K5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4604</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019819.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4604"/>
    <dbReference type="EnsemblBacteria" id="ADD44248">
        <property type="protein sequence ID" value="ADD44248"/>
        <property type="gene ID" value="Snas_4604"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4604"/>
    <dbReference type="eggNOG" id="ENOG502ZXQH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2588044_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="80" mass="8330" checksum="71211E0DD38EAD27" modified="2010-04-20" version="1">MTDTPSTGGYDGPPQSPPPPKGWKVPEVIAIAPPRDLPPQNQAAIDAAESRARTFSQGLAVLTAALLFVVLIVLLIRAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q738</accession>
    <name>D3Q738_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016008.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0725"/>
    <dbReference type="EnsemblBacteria" id="ADD40437">
        <property type="protein sequence ID" value="ADD40437"/>
        <property type="gene ID" value="Snas_0725"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0725"/>
    <dbReference type="eggNOG" id="ENOG5031XGF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121826_1_0_11"/>
    <dbReference type="OMA" id="FPPGRYG"/>
    <dbReference type="OrthoDB" id="1975587at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025443">
        <property type="entry name" value="DUF4307"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14155">
        <property type="entry name" value="DUF4307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="137" mass="14883" checksum="F29F3A099BDA4FA8" modified="2010-04-20" version="1">MDETRTTAVRFPPGRYGRRREGRKAQKWVLAAIGSVFVAGGLFVSLSMYNQYGGTDFSHQVVGFDTAESSVSITFEVFKPEGQAAICQIRARSADGADVGQAEAEIPAAKSEVRVEYTLETSAKPVTGEVLRCYPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Z4</accession>
    <name>D3Q7Z4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0787"/>
    <dbReference type="EnsemblBacteria" id="ADD40499">
        <property type="protein sequence ID" value="ADD40499"/>
        <property type="gene ID" value="Snas_0787"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0787"/>
    <dbReference type="eggNOG" id="ENOG50333C3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2221604_0_0_11"/>
    <dbReference type="OMA" id="WDKPELD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="1">
        <location>
            <begin position="23"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="106" mass="11771" checksum="8146A1ED1715993C" modified="2010-04-20" version="1">MNDNANDTVREHPLKGQFDTATAKWQRTTNLDGSPGKLEIGFADNGLVALRYAEEPDGTILIYTPAEWDAFVEGVKDGEFDIEVLEEDARKAAEEEEARLAAEDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7Z8</accession>
    <name>D3Q7Z8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016074.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0791"/>
    <dbReference type="EnsemblBacteria" id="ADD40503">
        <property type="protein sequence ID" value="ADD40503"/>
        <property type="gene ID" value="Snas_0791"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0791"/>
    <dbReference type="eggNOG" id="COG1432">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071591_0_0_11"/>
    <dbReference type="OMA" id="WYDGARR"/>
    <dbReference type="OrthoDB" id="788525at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="1">
        <location>
            <begin position="16"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="335" mass="36706" checksum="5A83141A64A832AE" modified="2010-04-20" version="1">MSLVRSDCSPVVARRYAMLIDVGYLYAAAAEVLLGATSRREYKVDAEKLINTLITRAADQLPGGELLRVYWFDAARDRVPTVDQRVIAAMALVKVRLGNLNSRGQQKGVDAMIRTDLEQLARHGAISEAILLAGDEDMVPAVEIAQAYGVRVHVWGVEPPYGTNQAERLLWEADTLDEISAEFCKPYFTKLGTAAAASAKIVGAPMAEPEPQQPSPASVFGGRHSVAVTMSAADALEEAEMARPSFVRSTTGDKFGQDTVTGIGEYVAHKWILTRGRENIADLLPGPTLPTVIDKELLVEAEKELGYSLREHPGARIWVRDGFWERVNREFDIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q829</accession>
    <name>D3Q829_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UbiD family decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016105.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0822"/>
    <dbReference type="EnsemblBacteria" id="ADD40534">
        <property type="protein sequence ID" value="ADD40534"/>
        <property type="gene ID" value="Snas_0822"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0822"/>
    <dbReference type="eggNOG" id="COG0043">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023348_4_1_11"/>
    <dbReference type="OMA" id="SYQQFWG"/>
    <dbReference type="OrthoDB" id="1012819at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022390">
        <property type="entry name" value="HBDC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002830">
        <property type="entry name" value="UbiD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108">
        <property type="entry name" value="PTHR30108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01977">
        <property type="entry name" value="UbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03701">
        <property type="entry name" value="mena_SCO4490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00148">
        <property type="entry name" value="TIGR00148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="485" mass="53446" checksum="C6B8902FC1A1026E" modified="2010-04-20" version="1">MAAKFPYGDLGEFLAALEADGDLKRVTAPVDTNLEISEITQRVVREGGPALLFENPTRGDMPIAINLFGTPQRMAKALGVNDLDEVGARIGALVKPELPVGFAGIREGLGKLMQLKSLPPKKVRSAPCQQVVYKGKDVDLNRLPGLQTWPGDGGIFHNFGLTHTKHPETGKRNLGLYRLQQHDSKTLGMHWQIHKDSTAHHAVAERRGERLPVAVAIGADPVVNYAAGAPLPGDIDEYLFAGFLRGERVEMVDCLTVPLQVPANAQIILEGYVEPGERLPEGPFGDHTGFYTPIEPFPVLHIECMTTRRDPVYHSIITSKPPQEDYGLGKATERIFLPLLKLLIPDIVDYNMPEPGVFHNCVIVSIRKRYPKHAQKIMNAIWGAHLLSLAKLIVVVDEDCDVHDLNEVAWRAFGNVDYSRDLVVTEGPVDHLDHASYQQFWGGKAGIDATAKLPTEGYTRGWPHEATMPSAIKATVDSRWAEYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8B7</accession>
    <name>D3Q8B7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA polymerase LigD, polymerase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018062.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2815"/>
    <dbReference type="EnsemblBacteria" id="ADD42491">
        <property type="protein sequence ID" value="ADD42491"/>
        <property type="gene ID" value="Snas_2815"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2815"/>
    <dbReference type="eggNOG" id="COG3285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008325_1_2_11"/>
    <dbReference type="OMA" id="ITECVHI"/>
    <dbReference type="OrthoDB" id="2061599at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014145">
        <property type="entry name" value="LigD_pol_dom"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02778">
        <property type="entry name" value="ligD_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="305" mass="32924" checksum="D59C252AE89F5959" modified="2010-04-20" version="1">MAPVSQRVRFGDRELTVSHLDKLMYPETGTTKADVIDYYARAAAVLLPHITGRILTRVRYPHGTGDVRFFEKHAPPAVPPWLRTATVPSKTHADGVTYVVADEPAALVWLANLYTIELHTPQWQLDDTAPDSTRRPDRLVIDLDPGEGAGITECVHIAHLVRERLEADGLIAYPKTSGKNGVHLVVPISGTQPAEQVIDYAKALARSLAAAHPRLVTATMGPRNRIGKVLIDWSQNNPAKTTVAAYSLRGQPRPVISTPITWSELDAGNTGPFGPEAVLGRVATLGDLHADVTTPGPPLPVAAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8L8</accession>
    <name>D3Q8L8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020031.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4819"/>
    <dbReference type="EnsemblBacteria" id="ADD44460">
        <property type="protein sequence ID" value="ADD44460"/>
        <property type="gene ID" value="Snas_4819"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4819"/>
    <dbReference type="eggNOG" id="COG0452">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118224_0_0_11"/>
    <dbReference type="OMA" id="LYVIACG"/>
    <dbReference type="OrthoDB" id="1429052at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="1">
        <location>
            <begin position="13"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="196" mass="21217" checksum="94D705668C759140" modified="2010-04-20" version="1">MPFQPVTSQPVLQVIVCGSPLAADIGEVLVPAVRDGWDVWVVASEYGIRFLDADAAEAVTGHPVHYRYRHPDDPVDVPYADAIVVVPATCNTLAKWTAGICDTLALGLLVEAYGRGCPVTVVPFSNRAQASHPAVVDSIGRLRGWGVNVLFGDDFFPLHEPGTGTQVQRAFPWGRVREEIARMRSSAPCRPWSKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8T8</accession>
    <name>D3Q8T8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aspartate--tRNA(Asp/Asn) ligase</fullName>
            <ecNumber evidence="6">6.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="6">AspRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Non-discriminating aspartyl-tRNA synthetase</fullName>
            <shortName evidence="6">ND-AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">aspS</name>
        <name evidence="8" type="ordered locus">Snas_4889</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + L-aspartyl-tRNA(Asx)</text>
            <dbReference type="Rhea" id="RHEA:18349"/>
            <dbReference type="Rhea" id="RHEA-COMP:9710"/>
            <dbReference type="Rhea" id="RHEA-COMP:9711"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.23"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.23" evidence="6"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4889"/>
    <dbReference type="EnsemblBacteria" id="ADD44530">
        <property type="protein sequence ID" value="ADD44530"/>
        <property type="gene ID" value="Snas_4889"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4889"/>
    <dbReference type="eggNOG" id="COG0017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004553_2_1_11"/>
    <dbReference type="OMA" id="CKQHTVR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050560">
        <property type="term" value="F:aspartate-tRNA(Asn) ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="PTHR43450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="7">
        <location>
            <begin position="156"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="6">
        <location>
            <begin position="201"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="222"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="230"/>
            <end position="232"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="418"/>
            <end position="421"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="6">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="447" mass="48777" checksum="8A22404CF7E3C6D8" modified="2010-04-20" version="1">MSTSMTAPSPAAPTTPPRVLSAALSEHVGARIRIAGWLHRRRLLKSVAFAIVRDRSGLAQVVVSEEVARARLEELNEETVVEVTGTVVANPAAPGGVELVEPVITVLGEAEAPPFDLYRPSLRATLPTLLDRAPVSLRHPRRKAAFELASAATMGFRETVAAMDFTEIFTPKIVASATESGANVFAIDYFGRPGYLAQSPQFYKQTMVGVFERVFEVGPVFRAEPHDTVRHLAEYTSLDVEFGFIESYRDVAEVLREVVAGMVSAVAERAAAAVALLEPVVPQVPSRFPELHFAEALELISRETGEDLSGVNDLSPAHERWVGEWARREHGSDFAVVVGYPMSKRPFYTAEDPGRPGYSDSFDLLFRGTEMVTGGRRLHRYADYLAAIAAQGGSPEPYAGYLEAFKHGMPPHGGFAIGLERFVAQLTGVANIREVTLFPRDLHRIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8Y1</accession>
    <name>D3Q8Y1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0879</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016161.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0879"/>
    <dbReference type="EnsemblBacteria" id="ADD40590">
        <property type="protein sequence ID" value="ADD40590"/>
        <property type="gene ID" value="Snas_0879"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0879"/>
    <dbReference type="HOGENOM" id="CLU_1474315_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="183" mass="20552" checksum="FB9E106E190326D8" modified="2010-04-20" version="1">MANDEAAEPVTAMRTLERLSKLTDARITATSPQGRARVTLQGGRHSVELRPEGFQKLDPKLLAEEVTHAFNGTLRGHRQQEQRILAEYREVRPHQPKPRAEAEQERVNRAREAVSVKATSASRLVRGTWSATDGVSLKIAAVNDSHREQLATEIAQVLNELSAKFRTDMREAVREARRQSRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9G0</accession>
    <name>D3Q9G0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidoglycan-binding domain 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018213.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42642">
        <property type="protein sequence ID" value="ADD42642"/>
        <property type="gene ID" value="Snas_2967"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2967"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1414406_0_0_11"/>
    <dbReference type="OrthoDB" id="2025306at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048337" evidence="1">
        <location>
            <begin position="32"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="80"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="198" mass="20924" checksum="E9334CC694B19AF0" modified="2010-04-20" version="1">MRNLKWKIAATASVVALGVGGAVGFSGVAAAEPTILTSTSFVDGLDKVTDDFNDHARELGAPLSDHGKNSWGTDIVIVWQAILAADGYLTYEGVDGYFGAKTAAATAKWQADRGIDADKPGTVGHTTWAYADNNLIADDGTVDYRTPGLGVVVFKRAPGPDGHYTLVSTADAADGYGWRNRGGDHIYFSKMTLRLALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9I8</accession>
    <name>D3Q9I8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="4">G6PD</shortName>
            <ecNumber evidence="4">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">zwf</name>
        <name evidence="7" type="ordered locus">Snas_2996</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018241.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2996"/>
    <dbReference type="EnsemblBacteria" id="ADD42670">
        <property type="protein sequence ID" value="ADD42670"/>
        <property type="gene ID" value="Snas_2996"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2996"/>
    <dbReference type="eggNOG" id="COG0364">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013524_5_0_11"/>
    <dbReference type="OMA" id="KWRVLHA"/>
    <dbReference type="OrthoDB" id="1153269at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 4" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="5">
        <location>
            <begin position="12"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="6">
        <location>
            <begin position="184"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="88"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD42670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="466" mass="51650" checksum="AF8F4CB298ACA21D" modified="2010-04-20" version="1">MTATVPRADALVLFGITGDLAKKMLFPALYHLAKRGRLDIPVVGVAAADWDDAALREHAYAAVVASVKRVNKAVFEKLASQLSLVTGDFKDPGTFDRLRDEVKGLGYLTHYLAIPPSLFTTVAQSLATVGLNQNSRLVVEKPFGHDLDSAKRLDVELARYFDEEHLLRVDHFLGSEPVEGLKVSRFANTLFATTLHRTCVDNVQISLAEDFDVADRGSFYDAVGCVRDVFQNHLLQVLSFLTMEPPSTPDAKVEKLEKWRVLHAARTIEPADTVRGQYHGYLDVDGVKPDSNTETFVAVKLWIDNWRWSGVPFYIRSGKCLALSATEIVVEMRRPPIDLYPALNGATPPNLIRFRLEPEAGLSIDVMVKKPEDGEDARPVPVDVDFAKALGREELPYENILDGAITGDREYFTSFPVVEECWRIVSRIIDTTDTPIRYVKGTWGPAAAELMPGPDGWHDIGSMGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9K0</accession>
    <name>D3Q9K0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Aldose 1-epimerase</fullName>
            <ecNumber evidence="4 7">5.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Snas_3011</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>alpha-D-glucose = beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:10264"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="5.1.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the aldose epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.3" evidence="4 7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018253.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3011"/>
    <dbReference type="EnsemblBacteria" id="ADD42682">
        <property type="protein sequence ID" value="ADD42682"/>
        <property type="gene ID" value="Snas_3011"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3011"/>
    <dbReference type="eggNOG" id="COG2017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031753_2_0_11"/>
    <dbReference type="OMA" id="ATWLSCK"/>
    <dbReference type="OrthoDB" id="1512477at2"/>
    <dbReference type="UniPathway" id="UPA00242"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004034">
        <property type="term" value="F:aldose 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019318">
        <property type="term" value="P:hexose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018052">
        <property type="entry name" value="Ald1_epimerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015443">
        <property type="entry name" value="Aldose_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005096">
        <property type="entry name" value="GALM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00545">
        <property type="entry name" value="ALDOSE_1_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 7 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048783" description="Aldose 1-epimerase" evidence="12">
        <location>
            <begin position="49"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="144"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="244"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="365"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ADD42682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="400" mass="43661" checksum="98AB09150A1A976E" modified="2010-04-20" version="1">MSKYATPDGISANVEQGSDLTRRAVVMGAGVLGLTGAVVATTAKPAAAKDPDRIPTKSTLDSGRLSVDKEPFGETAAGEAVDRYTFGSAKGLRVRMLTYGATIQAIEMPDRRGRRASVALGLPTIAEYESHGSYFGATIGRYANRIAKGQFTLDGETHQIPVNNGENALHGGPKGFDKRIWAATPIEEDDRVGVSFGYVSPDGEMGFPGTLNVTVDYTLDRHQRLTIAYRATTDRPTIINLTNHAYFNLGGQSSGTVEDQLLWVDADRYTPVDDSLIPLGPLDPVDDTRFDFRRPKTIGRDMGGEVYDHNWVLNDYSPGHQRLVLAAYDATSGRWLRCSTDQPGVQIYTGYSESADKKSDAFAVETQHYPDSPNQPDYPSTVLRPEETYETTTVYRFGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9U6</accession>
    <name>D3Q9U6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD linked oxidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020213.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5005"/>
    <dbReference type="EnsemblBacteria" id="ADD44642">
        <property type="protein sequence ID" value="ADD44642"/>
        <property type="gene ID" value="Snas_5005"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5005"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048432_0_0_11"/>
    <dbReference type="OMA" id="YIPSRHY"/>
    <dbReference type="OrthoDB" id="482388at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050614">
        <property type="term" value="F:delta24-sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040165">
        <property type="entry name" value="Diminuto-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801">
        <property type="entry name" value="PTHR10801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="447" mass="50507" checksum="750FA3ED28C69F69" modified="2010-04-20" version="1">MSRNEHDASVARLRAALLALPAGARVRLAKPSSNLFRFGGRDSSPGLPTDGLDSVIAIDPDNRTAEVGGLITYEKLVAATLPHKLMPHVVPQLKTITLGGAVAGLGIESTSFRDGLPHESVLEMDVLTGSGEIVTVHPDDPLFRGLPNSYGSLGYAVRLIIDLKPVSNTVALEYRRFDDPDAAFAALGEIWERGEVDFLDGVAFGPGETYLSLGRFTDEPGPVSDYTEEHVYYKSLRRRRSDRLTVHDYLWRWDTDWFWCSAALGVQNPVIRRLWPQPLRRSDVYRRLVALDRRVGITRRIDALQGKRREAVIQDVEIPLSRAPEFLREFCANVPIRPLWLCPLQLSGERTWPLYPLDRGERYVNFGFWATAMLRPGQAPDHHNRFVENLVDELGGHKSLYSTVHYDRDEFRRRYGGEAYDELKQRYDPGARLPDLYDKVVTDSATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9W5</accession>
    <name>D3Q9W5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020232.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5024"/>
    <dbReference type="EnsemblBacteria" id="ADD44661">
        <property type="protein sequence ID" value="ADD44661"/>
        <property type="gene ID" value="Snas_5024"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5024"/>
    <dbReference type="eggNOG" id="COG4319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137417_2_0_11"/>
    <dbReference type="OMA" id="YEKAMRP"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="118" mass="12847" checksum="E11DB33DB942417D" modified="2010-04-20" version="1">MNTRYEPASTPEELSRLVVERVNAGDAAGVAVLYETQAVVGFPSDNPTVGREAIAALYQRMVDAGAKFEVEDPLPTLYFEDLALTATRPKDGTGGRSQVLRRQPDGTWLRVLDRPEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Y6</accession>
    <name>D3Q9Y6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016269.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0988"/>
    <dbReference type="EnsemblBacteria" id="ADD40698">
        <property type="protein sequence ID" value="ADD40698"/>
        <property type="gene ID" value="Snas_0988"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0988"/>
    <dbReference type="HOGENOM" id="CLU_2358333_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="96" mass="10353" checksum="A415DEED1433BB06" modified="2010-04-20" version="1">MNFHAEPVDIDGHGRSVSDIGQDISEGTRKGRSLTLTLPGLTTGPAFESYRDAWLGQGDQISVNLNQDGDGTRKSGDAHEQNEQAITRGYNAINPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Z4</accession>
    <name>D3Q9Z4_STANL</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016277.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0996"/>
    <dbReference type="EnsemblBacteria" id="ADD40706">
        <property type="protein sequence ID" value="ADD40706"/>
        <property type="gene ID" value="Snas_0996"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0996"/>
    <dbReference type="HOGENOM" id="CLU_703796_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="392" mass="41076" checksum="AAB6C5E6CC23778B" modified="2010-04-20" version="1">MSETPYRRETAADEVISPFPSLVESRRLLSPEPEIDEAPAPAPAASASAPVPADTRDAEPKRSLIRRWLKSRKQSDPQPEPEPAPPQPLVPVRRRIAELMDKPEEEAEQSVADKAVKAAPKRRELEAAPSAPEVSDELAAVDTVRLGGDEKQPVEEAATVDAVRPENHKRATIDSGKREDGESAAAESQSPGGADREPAEPVRYGAVFESAPDQLRVPPQAGPQVGRLVGAGAGPKPPTPKAEPVADAEPVSKALVKFTPDVKPSVGARDEAAAAPKPQQAVTESKAKPEWKETVKKLAAAVSEADAAKAGSAAKAEAGDAAKQSIATKTETAVAEEDPVDEPGEPGLDEDEPAPVLRVRGPGVPSGRTYKPGTAVEAAPALRVRGPQLPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9Z6</accession>
    <name>D3Q9Z6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative exporter of polyketide antibiotics-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016279.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0998"/>
    <dbReference type="EnsemblBacteria" id="ADD40708">
        <property type="protein sequence ID" value="ADD40708"/>
        <property type="gene ID" value="Snas_0998"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0998"/>
    <dbReference type="eggNOG" id="COG3559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036785_2_0_11"/>
    <dbReference type="OMA" id="GDRWWVL"/>
    <dbReference type="OrthoDB" id="1885421at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="505"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="529" mass="55736" checksum="7FDA0CF2E2204442" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA70</accession>
    <name>D3QA70_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SseB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016353.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1072"/>
    <dbReference type="EnsemblBacteria" id="ADD40782">
        <property type="protein sequence ID" value="ADD40782"/>
        <property type="gene ID" value="Snas_1072"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1072"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012380_0_0_11"/>
    <dbReference type="OrthoDB" id="1217758at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009839">
        <property type="entry name" value="SseB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07179">
        <property type="entry name" value="SseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SseB" evidence="2">
        <location>
            <begin position="21"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD40782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="704" mass="76458" checksum="E58E7405B5661A40" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAA5</accession>
    <name>D3QAA5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl-CoA hydratase 2</fullName>
            <ecNumber evidence="1">4.2.1.119</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Enoyl-CoA hydratase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_3017</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26526"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57319"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="EC" id="4.2.1.119"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.1.119" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018259.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3017"/>
    <dbReference type="EnsemblBacteria" id="ADD42688">
        <property type="protein sequence ID" value="ADD42688"/>
        <property type="gene ID" value="Snas_3017"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3017"/>
    <dbReference type="eggNOG" id="COG2030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056696_0_0_11"/>
    <dbReference type="OMA" id="YPHVLGF"/>
    <dbReference type="OrthoDB" id="942354at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC-like" evidence="5">
        <location>
            <begin position="186"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="285" mass="31742" checksum="F919BD9C9CBD480D" modified="2010-04-20" version="1">MRSHIMAQYPKAALSLLRRGRGDAASARLPEAELVSQDVTVDARDYARYCRLTGFRLSGELPVTYPHLLGFDAAMSLFTHREFPFSPVGMVHSSNRILQHSPLTVDDTLTVRVRLDNLAPHPKGATFDTVTEVERGGETAWSEASTYLIRTKSPDAEAHTRPRPEVDLDLDDLEALWPVPGYIGRRYAAVSGDYNPIHLHPLSARVFGQRRAIAHGMWALARCLGALENRIAPPPRVVETDFRRPLPLPSPKVALCTDREQTSWHFGLFNPKTAKSYLTGWASPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAB7</accession>
    <name>D3QAB7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helix-turn-helix type 11 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3029</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018271.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3029"/>
    <dbReference type="EnsemblBacteria" id="ADD42700">
        <property type="protein sequence ID" value="ADD42700"/>
        <property type="gene ID" value="Snas_3029"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3029"/>
    <dbReference type="eggNOG" id="COG2378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041141_5_0_11"/>
    <dbReference type="OMA" id="VWYLCAR"/>
    <dbReference type="OrthoDB" id="1654295at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028349">
        <property type="entry name" value="PafC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016838">
        <property type="entry name" value="PafC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="2"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="327" mass="36009" checksum="A769A0C2C0C6B962" modified="2010-04-20" version="1">MRAARLISMVLLLQNRGSLTADQLSAELGVSPRTIARDATELAEAGIPVYAEQGRGGGYRLLDGFRTRLTGLGRAEVEALFLSGAPEALSGMGLDSAALAARLKIGAALAPSVREAPRRVGQRFHLDAPGWFRKLETPDALAELSSAVWSDRLVEVRYRRGRRLGETAEPEPVTRTLAPFGLVLKAGVWYLVAGVGDDVRIYRVDRFDDVAVADTEFTRDEDFDLAAFWRRQQEEFAASMMREHIVVRLSPDGRQRLHRAVDAATVAGAEFDEPDADGWTRARLPVETLDVAYEEMLSLGPDVEVVEPKPLRARLAEAARRLGELYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAB9</accession>
    <name>D3QAB9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyltransferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3031</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018273.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3031"/>
    <dbReference type="EnsemblBacteria" id="ADD42702">
        <property type="protein sequence ID" value="ADD42702"/>
        <property type="gene ID" value="Snas_3031"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3031"/>
    <dbReference type="eggNOG" id="COG1835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005679_1_3_11"/>
    <dbReference type="OMA" id="LYLWHEP"/>
    <dbReference type="OrthoDB" id="1979131at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="3">
        <location>
            <begin position="24"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="438" mass="48542" checksum="EA82A4A716AA5591" modified="2010-04-20" version="1">MKTIRPGAVDDAGGSVATSQRLEVHGYRALAAVSVMTFHAYQNNWRAPDWKWPLEGTIWHEVMLATDLCVDLFFVLSGLLLGLQYAKSCLGEAAPRSGRALLLRRATRLIPLYYIVVCTVWAITNPDLPGNWRDLVLHLTFTHVYSQEYIFYTDGPAWSLANEMHYYLLLALLGALAQKCCQRLRTRGAKLTLLIGGTLTLIGASVVYKLAAAYVYHVPADHWPTWFGPLAKLDVFAVGLLISIFYAAGLRFRHGLTQILVLLSGMAILAAGLYLRPAQGVEPLLHPAFAAGCGLLIASTAMGTTIRPRWLKWRPLVSVSMASYSLYLWHEPIMRYLRYIGALPDHRHPLAFPITAIMVFCAAVPVAIISYKLIEMTGQKLMAAFDSRGRPRDYYADALAESPSPSPSLPTQRAPAAGRHTRRFGPDRVTSSNFVDKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAY3</accession>
    <name>D3QAY3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_5144</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020350.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5144"/>
    <dbReference type="EnsemblBacteria" id="ADD44779">
        <property type="protein sequence ID" value="ADD44779"/>
        <property type="gene ID" value="Snas_5144"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5144"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_11"/>
    <dbReference type="OMA" id="AVHIRHI"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="13"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="137"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="137"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="236" mass="26644" checksum="CBEC4119877D9D56" modified="2010-04-20" version="1">MAVTEEDREGEATLLVVEDDPNICELLATSLGYAGFTVHRAEGGEEAVRAVARHRPDLVVLDVMLPDFDGFEVARRIRSGSDRTPIVYLTARDALEDKVRGLTLGGDDYVTKPFSLEEVIARIRAVLRRSKGDAPPPPRLQYADLELDEETHEVWRGGNSVQLSPTEFKLLRYFMVNAGRVLSKAQILDHVWRYDFRGDDGIVESYVSYLRRKIDNTEPRLIQTLRGIGYVLRTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAY8</accession>
    <name>D3QAY8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020355.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5149"/>
    <dbReference type="EnsemblBacteria" id="ADD44784">
        <property type="protein sequence ID" value="ADD44784"/>
        <property type="gene ID" value="Snas_5149"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5149"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_7_2_11"/>
    <dbReference type="OMA" id="FINYCQY"/>
    <dbReference type="OrthoDB" id="1465613at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="136"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="329" mass="34812" checksum="7BE7601560B4209F" modified="2010-04-20" version="1">MTDSIGWGILATGGIAATFTEDLKRLPDAHVAAVGSRSPETARAFAERFDIPAAHGSWDDLIADPDVDIVYIANTHNAHYEAAKRCLEGGKAVLCEKAFTVNHVQAKTLVDLAGERGLFLMEAMWMRLNPAIRHMRKALTDGLIGDVTTLNATFGLGGPFPPGHRLRDPNQAGGALLDLGVYPISLAQLILGRPASIHATGSLTPEGVDATAGLVLGYDSGAVATLACSITSDMPIVASVNGTTGHVTLPAPFFRPSRYLLGRGGGEAELEIVEVPHDGLGYVHQAIEAMRCLREGLTESPLVPWQSTLDVMAVMDEARSQLGVTYPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB37</accession>
    <name>D3QB37_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyltransferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_1144</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1144"/>
    <dbReference type="EnsemblBacteria" id="ADD40854">
        <property type="protein sequence ID" value="ADD40854"/>
        <property type="gene ID" value="Snas_1144"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1144"/>
    <dbReference type="eggNOG" id="COG1835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005679_1_1_11"/>
    <dbReference type="OMA" id="HSHEYLQ"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="3">
        <location>
            <begin position="16"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD40854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="376" mass="42187" checksum="10F339ACC697C6AE" modified="2010-04-20" version="1">MQSLSYRDYRDTRRFAALDGLRAVTVLGLIAHHFQAGKLQPLIGIGKITVFFVLSGFVITLLLLRTEDKSGSIKLRGFYLRRQFRLLPLYYTALAVYCVARFSVGDEWDRLREALPYYLVFLNEYSPTDPDITSFWHSWTLGYEQKFYLVWPLIFIALSRLAPKSRPWWTLGLAGACLALMPVTDGTPVHYFSLFLGCALAMFMHTEGTYRLVRPLTHPVASFAVLCGFAALHLWLPTIARNLGSERYAFVFYALGVAVLIVAIVNSGVGRWVLTRPPLLFIGERGYAMYLFHGIAGAAVMGLAPQWGGSPVRWLLICLVTVVFAEVAHRLVELPFADMGRRFNAWLDQRKAARANAPMPRQHAGEAPAPQPAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB73</accession>
    <name>D3QB73_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5 7">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsL</name>
        <name evidence="9" type="ordered locus">Snas_1180</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1 5 7">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5 7">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016461.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1180"/>
    <dbReference type="EnsemblBacteria" id="ADD40890">
        <property type="protein sequence ID" value="ADD40890"/>
        <property type="gene ID" value="Snas_1180"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1180"/>
    <dbReference type="eggNOG" id="COG0048">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104295_1_2_11"/>
    <dbReference type="OMA" id="SPALEKC"/>
    <dbReference type="OrthoDB" id="1707228at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="124" mass="13893" checksum="10F97EA6A7092286" modified="2010-04-20" version="1">MPTIQQLVRKGRKDKVSKNKTPALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVRLMSGFEVTAYIPGVGHNLQEHSIVLVRGGRVKDLPGVRYKIVRGSLDTQGVRDRKQARSKYGAKKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBD9</accession>
    <name>D3QBD9_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="5">2.1.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aspartate transcarbamylase</fullName>
            <shortName evidence="5">ATCase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pyrB</name>
        <name evidence="9" type="ordered locus">Snas_3150</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3150"/>
    <dbReference type="EnsemblBacteria" id="ADD42821">
        <property type="protein sequence ID" value="ADD42821"/>
        <property type="gene ID" value="Snas_3150"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3150"/>
    <dbReference type="eggNOG" id="COG0540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043846_2_0_11"/>
    <dbReference type="OMA" id="FPTEREY"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00001">
        <property type="entry name" value="Asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="4"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="153"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD42821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="309" mass="32965" checksum="38CD4CCD69F6E9E0" modified="2010-04-20" version="1">MIEHLLSAADLDLESATLILDTAKEMDAAMSGREVRKLPTLRGRTVVNLFFEDSTRTRVSFEAAAKRLSADVVTFSAKGSSVSKGESLKDTALTLQAMGADAVVVRHSAAGAANRLTGWLDGSVVNAGDGTHEHPTQALLDAYTIRQRLGRLEGLRVAVVGDILHSRVARSNVALLNTFGAKVTLVAPPTLVPVGVGSWPVEVAYDFDAVLPHTDVVMMLRVQAERMNASFFPSAREYSRRYGLDGARLARLPDEAIVMHPGPMNRGMEIAASVADSPRSVIVDQVANGVLVRMAVLYLLLSGHKGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBM5</accession>
    <name>D3QBM5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable phosphoketolase</fullName>
            <ecNumber evidence="5">4.1.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_3237</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the XFP family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.-" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018478.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3237"/>
    <dbReference type="EnsemblBacteria" id="ADD42907">
        <property type="protein sequence ID" value="ADD42907"/>
        <property type="gene ID" value="Snas_3237"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3237"/>
    <dbReference type="eggNOG" id="COG3957">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013954_2_0_11"/>
    <dbReference type="OMA" id="LSTMDHC"/>
    <dbReference type="OrthoDB" id="45239at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01403">
        <property type="entry name" value="Phosphoketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023962">
        <property type="entry name" value="Phosphoketolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005593">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018969">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019790">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018970">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019789">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_ThDP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31273">
        <property type="entry name" value="PTHR31273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03894">
        <property type="entry name" value="XFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09363">
        <property type="entry name" value="XFP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09364">
        <property type="entry name" value="XFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017245">
        <property type="entry name" value="Phosphoketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60002">
        <property type="entry name" value="PHOSPHOKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60003">
        <property type="entry name" value="PHOSPHOKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="XFP_N" evidence="7">
        <location>
            <begin position="12"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="XFP_C" evidence="6">
        <location>
            <begin position="590"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="798" mass="88760" checksum="174F733D34974D29" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBP1</accession>
    <name>D3QBP1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Xylulose kinase</fullName>
            <shortName evidence="3 5">Xylulokinase</shortName>
            <ecNumber evidence="3 5">2.7.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">xylB</name>
        <name evidence="8" type="ordered locus">Snas_3253</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17140"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the FGGY kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.17" evidence="3 5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018494.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3253"/>
    <dbReference type="EnsemblBacteria" id="ADD42923">
        <property type="protein sequence ID" value="ADD42923"/>
        <property type="gene ID" value="Snas_3253"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3253"/>
    <dbReference type="eggNOG" id="COG1070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009281_12_0_11"/>
    <dbReference type="OMA" id="SFSGQMM"/>
    <dbReference type="OrthoDB" id="1619686at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004856">
        <property type="term" value="F:xylulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005998">
        <property type="term" value="P:xylulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02220">
        <property type="entry name" value="XylB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006000">
        <property type="entry name" value="Xylulokinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01312">
        <property type="entry name" value="XylB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00933">
        <property type="entry name" value="FGGY_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 3 5" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="FGGY_N" evidence="6">
        <location>
            <begin position="4"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="7">
        <location>
            <begin position="239"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="69"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="site" description="Important for activity" evidence="3">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD42923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="464" mass="47542" checksum="F0FAA847C8B99525" modified="2010-04-20" version="1">MTLVAGIDSSTRSTKVLLVDAETGQVVDSGTAPHPDGTECPPQVWWDALQQAGGDLIDRAEAVAVSGQQHGLIALDEHGEVIRPALLWNDTRSAPQAARLTGEGGGPGVWAQRTGSVPTASFTVTKLAWLAEHEPDNAERTAAVLLPHDWLTLKLRGVGFAEATTDRSEASGTGYWSPDTGVYLRDTVIGALGHDAVLPRVAAPNEIVGHTPNGVAVAPGTGDNAGAALGLRLESGDVVISLGTSGTVFGVAEAPAADPTGLVAGFADATGRFLPLVCTLNAAGVLDTVRDLLNVDHAGFDALALAAAPGSGGLTLLPYLDGERTPNRPNATGVLSGLTTHTTRADLARAAVEGMLSAQADGLAALSAQGLRAGRVLLIGGASSSEAVRRIAPHVFGLDVEVPPTAEYVALGAARQAAWALSGRPHPPQWNTGAATGFIGRAATSVTEQYSTLRDETASWTSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBS8</accession>
    <name>D3QBS8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamine--fructose-6-phosphate transaminase (Isomerizing)</fullName>
            <ecNumber evidence="4">2.6.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5182</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.6.1.16" evidence="4"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5182"/>
    <dbReference type="EnsemblBacteria" id="ADD44817">
        <property type="protein sequence ID" value="ADD44817"/>
        <property type="gene ID" value="Snas_5182"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5182"/>
    <dbReference type="eggNOG" id="COG2222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012520_2_1_11"/>
    <dbReference type="OMA" id="QSFYVMA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SIS" evidence="3">
        <location>
            <begin position="52"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="3">
        <location>
            <begin position="222"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="369" mass="38092" checksum="0E10BFDD812B5B9F" modified="2010-04-20" version="1">MSQQQAARSTTAGATDATAATPPGAGMAADIADQPEAFARLAETQSGAIADIAAEIARERPRFVMFTARGTSDHAALYAAYLTEIRLGIPAGLASPSAITVYGARPDLSEALVVGVSQSGGSPDIAEVLRVASESGARTLAVTNNPESPLAKQAGLNIDVSAGHEKAVAATKTYTAELLALFMLIEGIRAGDGKLAGDEAAAVAALPELARTVLADETPVQLAARYRFAERLVTTGRGYAYPTARETALKLMETSYLSALSFSGADLLHGPLAMADPDIPVLAIVGDGPGGNAMRDVIGRLGERRADVVSIGASDVEGAPIRIPVPAVDERLAPMLDILPLQRLALALALNRGENPDAPRGLRKVTETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBY0</accession>
    <name>D3QBY0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020440.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5235"/>
    <dbReference type="EnsemblBacteria" id="ADD44869">
        <property type="protein sequence ID" value="ADD44869"/>
        <property type="gene ID" value="Snas_5235"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5235"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1894909_0_0_11"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="66"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="134" mass="14798" checksum="8795E7A264C7E257" modified="2010-04-20" version="1">MSTLFTPDLRNPVVAWEVIARSAVHIVREARASRRLEPLSIDGRMLFKAVAALGIDLEPPKPTALRTSIQRGLSARESQVLLAIASGKSNAEIGRELFITEDTVKTHARRMYRKLGARDRAHAVAEAFRVGILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3QC30</accession>
    <name>D3QC30_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020490.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5285"/>
    <dbReference type="EnsemblBacteria" id="ADD44919">
        <property type="protein sequence ID" value="ADD44919"/>
        <property type="gene ID" value="Snas_5285"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5285"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091228_2_1_11"/>
    <dbReference type="OMA" id="NFLMIKC"/>
    <dbReference type="OrthoDB" id="1431378at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="2">
        <location>
            <begin position="50"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="220" mass="24234" checksum="74063AF27719BF15" modified="2010-04-20" version="1">MTHNGDDLGAGQRRHWQSTYSDNPGMYGAEPSQAAVHAAETFTASEARDVLELGSGHGRDTLFFARAGFAVRALDFSETGLWQLRETATQAGIADRVTTTVHDVRQPLPLADDSVDAVFAHMLLCMALSTDELHTLMAEIRRVTRPGGTFVYTVRHTGDAHYGTGISHGDDIYEHGGFAVHFFDEALVTELARGWKLGEVFDFSEGELPRRLWRVTQTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU76</accession>
    <name>D3PU76_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP synthase subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP synthase F(1) sector subunit delta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">F-type ATPase subunit delta</fullName>
            <shortName evidence="6">F-ATPase subunit delta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atpH</name>
        <name evidence="7" type="ordered locus">Snas_1313</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="6">This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ATPase delta chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016593.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1313"/>
    <dbReference type="EnsemblBacteria" id="ADD41022">
        <property type="protein sequence ID" value="ADD41022"/>
        <property type="gene ID" value="Snas_1313"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1313"/>
    <dbReference type="eggNOG" id="COG0712">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088880_0_0_11"/>
    <dbReference type="OMA" id="FRFGRIV"/>
    <dbReference type="OrthoDB" id="1937493at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="PTHR11910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0139">CF(1)</keyword>
    <keyword evidence="2 6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="3 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD41022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="275" mass="29348" checksum="B1649D6FC1EF128F" modified="2010-04-20" version="1">MSITGQQSVQAGYEALEAYAKRVKPETLDKVASELLAVKDLFANEPRLRRALTDPGRTAAERSGLAEQVLSGKVSAGTLKVLTALIGQRWSTPGELLTAVESIGVDAILRVGAAQDVLAEVEDELFRFARLVDGDNDLSRALSDGSAPASARTELVRTLLSGKANAVSVRLAEVAAAGFGGRRGFDTAATKLLELVSAKREQRLAYITVAAPLPQDQEARLTRKLSEIYGHTISAKITVDPQVVGGIRVQIGHDLYDGTVARRLTEARKALAARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUF2</accession>
    <name>D3PUF2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018536.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3297"/>
    <dbReference type="EnsemblBacteria" id="ADD42965">
        <property type="protein sequence ID" value="ADD42965"/>
        <property type="gene ID" value="Snas_3297"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3297"/>
    <dbReference type="eggNOG" id="ENOG5033RPY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038050_0_0_11"/>
    <dbReference type="OrthoDB" id="2129681at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="393" mass="42227" checksum="F1FB0B68CDEADA83" modified="2010-04-20" version="1">MAVQRDLRGLTIALALRSFALALVNVFLPLLMLEQGAALWQVCAFYVVYSAAKMAINYPSVILIERWPPWLGLAVALASSAVYLLLLNTYISGAAWAIWCAPAALAGMNAFLWNSQHIHISRALQDTRRGRDMAVINVVIHVATLAAPPIGAALVAFGGRSTLLFAALTVIALAILPARAAHRLPRRPSDEDGPSRPAPFRDLVANFAYNTSILVHFLLWPVYLAVVFGDFTTIGLITAVTEGVGLLLLLVAGRRGDRGATWRVLLEGTIATALAHLARLLAGTPLSITVVGAVSRAAIDYQQIPWVTTYYSHVKQRGSRYVLWMEGAGDLANLLIWLALLVAAILTQHATVFFGIAFVLAAVATIATLLISRQPMPVPQPRPAASVEATPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUK0</accession>
    <name>D3PUK0_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="5">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3347</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018584.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3347"/>
    <dbReference type="EnsemblBacteria" id="ADD43013">
        <property type="protein sequence ID" value="ADD43013"/>
        <property type="gene ID" value="Snas_3347"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3347"/>
    <dbReference type="eggNOG" id="COG0722">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030903_0_1_11"/>
    <dbReference type="OMA" id="DINTGLR"/>
    <dbReference type="OrthoDB" id="853329at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DHAP_synth_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PTHR21225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="6">
        <location>
            <begin position="49"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="356" mass="37873" checksum="E39C0D00507BEF87" modified="2010-04-20" version="1">MTTTENSPQTNDLRVLGFQPLVPPSVLRDELPLGSDRAALVQRGREAVKQVLDGDDDRLLLVIGPCSVHDPVAAVEYANRLAEAAAPLSDVLCVVMRVYFEKPRTTLGWKGLINDPNLNGTYDVEHGLRLARQVLLDVLDVGLPVGCEFLEPTSPQYIADAVSWGAIGARTPESQVHRQLASGLSMPIGFKNATDGNVTAAIDGCRAAAGSHVFFGIDEQGRGAIVSTSGNPDCHVILRGGRGGPNYQPEPVGEALALLGKAGMPERLVIDASHANSGKDHVRQAQVVREVAERIAAGENGIAGLMVESFLVEGRQEPGALETLNYGQSVTDACIGWQETEALLTELATAVRKRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUL6</accession>
    <name>D3PUL6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3364</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018600.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3364"/>
    <dbReference type="EnsemblBacteria" id="ADD43029">
        <property type="protein sequence ID" value="ADD43029"/>
        <property type="gene ID" value="Snas_3364"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3364"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038683_1_1_11"/>
    <dbReference type="OMA" id="TPLWPLY"/>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="9"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="399" mass="40779" checksum="035CB4B420DCCA35" modified="2010-04-20" version="1">MTASPRRFAATSVAFAFWICMAGTTVPTALYPLYQNEFSFSAPMVTVIFAVYAAGVVCGLLVFGRLADQIGRKPTMLIALTLSLAAAAVFLLATGTTMLLIGRVLSGLSAALITGAATAALSELIPPDGPIRSASVALWANMGGLAGGAFLASAIADGTSQPLLTPWWATAALALLASLALWPLPETARARSRFAMQKLHFPSEIRADFTRSAATASAGFAVLGVLTALTGKFLHTVVPDAGHWVTGAMVATAFLSTALGQFLARALPSGFRLPAACLGLIAAAALVGTAVSLTSWPLLLCGAATVGLSTGIAMAFGLSAITTRSRPEHRGASVSTFFAILYTMLALPAVGVGLVTQATSLPVAARTLSTVVAAGAAVVLFSLLWSQRDAEPARVGGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUQ5</accession>
    <name>D3PUQ5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent pyridine nucleotide-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020500.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5295"/>
    <dbReference type="EnsemblBacteria" id="ADD44929">
        <property type="protein sequence ID" value="ADD44929"/>
        <property type="gene ID" value="Snas_5295"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5295"/>
    <dbReference type="eggNOG" id="COG0492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031864_5_0_11"/>
    <dbReference type="OMA" id="PICDGYE"/>
    <dbReference type="OrthoDB" id="2049098at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="14"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="323" mass="33529" checksum="360E48C14F08A97F" modified="2010-04-20" version="1">MRKTSENDNEQLVDVLVIGGASAGLSGALTLARARRSVVVIDSGKPRNLPAAASHGFLTRDGVAPTELVRLGAEEVAAYGGTVVTDIVTGVSGHNGDFTVTTEAGRSFHARRLLVTTGLSDELPDVPGLWQRWGRDVFHCPYCHGWEVRDQPIGVLDSGPNGVHQALLLRQWSDSVTLFLHRAADPSDEQFAQLAARGITVVDGEVSGLDIVDDQLAGVRLETGTRLPVRALAVAPTFTARAGFLADLGLTTVEHPSGMGDHLAADANGLTAVAGVWAAGTVTDPMANVAMSVGAGARAAVMLNADLMFADVAEAVADTGLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUR9</accession>
    <name>D3PUR9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020514.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5309"/>
    <dbReference type="EnsemblBacteria" id="ADD44943">
        <property type="protein sequence ID" value="ADD44943"/>
        <property type="gene ID" value="Snas_5309"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5309"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063235_0_0_11"/>
    <dbReference type="OMA" id="HETVRWD"/>
    <dbReference type="OrthoDB" id="1617768at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="236"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="318" mass="34670" checksum="F7CD9CF7B02E11FC" modified="2010-04-20" version="1">MHSFEFSADDLARTRYAVSPVHELVWSTVTLRKPRKAALHAPWREAVLAKLDPRRFELLFALTSGRTYLPDFLHPAPTRQRPGLRDQLSTVAATDEALAVAQVRRIATEPAPPLREFLARPRAGLDRLVDMMDDYFTAALAPHWPRIRGIAEADIAHRANLTSAHGAAATINDLHSRLSWNGTILDIHIGSSDEPVRNIRDAVLVPCCFAWPTVHPSTAADPDITIAYPPRGVGRLWQSSTARRTDATADLLGTTRTAVLRLLEAAHTTGEVAQALGLSAATASHHLVVLRNAGLAAADRDGRAVRYSRTPLGDTLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUS1</accession>
    <name>D3PUS1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5311"/>
    <dbReference type="EnsemblBacteria" id="ADD44945">
        <property type="protein sequence ID" value="ADD44945"/>
        <property type="gene ID" value="Snas_5311"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5311"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048109_1_0_11"/>
    <dbReference type="OMA" id="WTGRANS"/>
    <dbReference type="OrthoDB" id="1389691at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="179"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="311" mass="33060" checksum="2BB55DEA7CCD74B8" modified="2010-04-20" version="1">MMSSVRIGDRVVVRRAAGIIDGRQRYTDVLGELLDDSGGYTVRRDDGEVVTIPAAEVAAAKAIPPKPTPFSAIIAVERGCADTWPAPEQEWLGDWLLRAGSGWTYRANSVLPLGEPGLDLDAALAKVTDWYTARALAPAFAVPVPLSRRLATALTRRGWRSDAPVEVMTAPLSALSGEAAEVTVTDKPGEEWFAMATGGYDRVPDAARAILGSGDDRGFAEIRRDGRLIACGRGAISGGLAVLSRIEVDTSVRRQGLGRQVMAGLAAWAGDRDADTACVQVVSTNGVALALYEKLGFTVHHRYVNLVPPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUT0</accession>
    <name>D3PUT0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5320"/>
    <dbReference type="EnsemblBacteria" id="ADD44954">
        <property type="protein sequence ID" value="ADD44954"/>
        <property type="gene ID" value="Snas_5320"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5320"/>
    <dbReference type="HOGENOM" id="CLU_1250001_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="22399" checksum="14ED3C38749F76BE" modified="2010-04-20" version="1">MATFDSGRDEGDEPFAIGAVAGAGPELDVGEGAGLVGAQQSQHAGVREPDLGGVAPGQRPAQCVQVATLDGVDLVGEDLPGPRIGLAEHPAEESRHVAAPVAVGPGEVGGRFDERAHQRGHVGWPWCRFEFVQAAGAFGVDGPHGVVDDRPQQAVLGAEVVVDRGDVGGGCLGQGPRRGGLDAVLAEQPGGGRDQSVACGLGVSRRRHGGSLVVDGGRHML</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUT7</accession>
    <name>D3PUT7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5327</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020532.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5327"/>
    <dbReference type="EnsemblBacteria" id="ADD44961">
        <property type="protein sequence ID" value="ADD44961"/>
        <property type="gene ID" value="Snas_5327"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5327"/>
    <dbReference type="eggNOG" id="COG2130">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_29_2_11"/>
    <dbReference type="OMA" id="GKDKCDY"/>
    <dbReference type="OrthoDB" id="474248at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PTHR43205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="2">
        <location>
            <begin position="18"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="335" mass="35731" checksum="7D428096D5B232F2" modified="2010-04-20" version="1">MTHTATEIHLARRPEGWPVPEDFTTVTTDLPEPGPGQVLIRNRFISVDPYMRGKMNDVPSYTPPYQLNTPMDGGAIGVVEASGAENIAVGRTVLHQGGWRDRALLDATEVRVVDEAQVSSLSAYLNGLGMTGLTAYTGLLDVANFKPGDTVFVSGAAGAVGQMVGQIAKLKGAKRVIGSAGSTEKVTYLTERLGFDTAFNYKDGPVSEQLKAAAPDGIDVYFDNVGGDHLEAAISSMNVNGRIAICGAISQYNATTPPTAPRNLALFIGKRITMTGFLVLDRFDRMKDFIADIAPHLASGKIVTEETIVDGIDNTVNAFLGMLRGENVGKMLVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUU1</accession>
    <name>D3PUU1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-hydroxybutyrate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020536.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5331"/>
    <dbReference type="EnsemblBacteria" id="ADD44965">
        <property type="protein sequence ID" value="ADD44965"/>
        <property type="gene ID" value="Snas_5331"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5331"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_11"/>
    <dbReference type="OMA" id="GALPHMY"/>
    <dbReference type="OrthoDB" id="1094766at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003858">
        <property type="term" value="F:3-hydroxybutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011294">
        <property type="entry name" value="3-OHbutyrate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01963">
        <property type="entry name" value="PHB_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="256" mass="27102" checksum="38E8AF4172A3E058" modified="2010-04-20" version="1">MTSLPFDEGLSGRTVVITGGASGIGLACVHRFAAAGAKVVVADVSQAAEQVAAEVGGTAWIADLSNPDSVDECPVSLRDTDILVNNAGAQHVAPLHEFPSEVFARLQRLMVETPFRLIRAVLPGMYERDWGRIVNISSVHGVRASPFKAAYVAAKHALEGLSKVVALEAAEHGVTSNCVRAAYVRTPLVERQIAEQARLHGLSKAEVVERIMLRPTAIKRLVEPEEVADSALYLCSGAAAFVTGSAITLDGGWTSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV56</accession>
    <name>D3PV56_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016680.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1402"/>
    <dbReference type="EnsemblBacteria" id="ADD41109">
        <property type="protein sequence ID" value="ADD41109"/>
        <property type="gene ID" value="Snas_1402"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1402"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_5_4_11"/>
    <dbReference type="OMA" id="HLEEWIK"/>
    <dbReference type="OrthoDB" id="1581636at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="24"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="204" mass="21504" checksum="1BD212AC374FD6AE" modified="2010-04-20" version="1">MRITVEKVITSGVFTLDGGSWDVDNNVWLIGTDTEVLVIDAAHDSRAIAKAVGDRRVSAIVCTHAHNDHVNAAPKLARALSGEVPILLHPDDRVLWDQTHPDRAPDADLSDGQTLTIGGLRLEVLHTPGHAPGAVCLYAPQLGAVFTGDTLFEGGPGATGRSHSDRDTLVASIKAKLMELPPETVVHTGHGPDTTIGAEADNLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVR7</accession>
    <name>D3PVR7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3518</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3518"/>
    <dbReference type="EnsemblBacteria" id="ADD43181">
        <property type="protein sequence ID" value="ADD43181"/>
        <property type="gene ID" value="Snas_3518"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3518"/>
    <dbReference type="HOGENOM" id="CLU_2275715_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048401" evidence="2">
        <location>
            <begin position="38"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="102" mass="10903" checksum="1F4E2BF0C92FF4E1" modified="2010-04-20" version="1">MTATLRSPPQLATLVMTLAMFLRAKPTAQRPVVTVTAANGESLEVTTSPDPHKIRQAYIAMDKEPPPPALTSAVSGDIIDAEIADEPQPDIHQNSTRSAIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVS9</accession>
    <name>D3PVS9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lanthionine synthetase C family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020621.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5418"/>
    <dbReference type="EnsemblBacteria" id="ADD45050">
        <property type="protein sequence ID" value="ADD45050"/>
        <property type="gene ID" value="Snas_5418"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5418"/>
    <dbReference type="eggNOG" id="COG4403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049438_0_1_11"/>
    <dbReference type="OMA" id="THMINTP"/>
    <dbReference type="OrthoDB" id="393144at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd04793">
        <property type="entry name" value="LanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033889">
        <property type="entry name" value="LanC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="409" mass="42700" checksum="787464E276BCA6B1" modified="2010-04-20" version="1">MTTIEEQVLTVADRLLKPEAVLNAVGRADAASLTRGLAGTALLHARLAHIDPRFARAAQQHWTAAAAHLKNHRHGFSGIAGGQGGLAASLIIGTGYLPEGNRHHAAAAGASWLAVCARDAADLYQRTDLLTWDVYDAITGLSGIGRVLLAAQSSGYDDVESGLMAALTALTAILEPRDTGRPGWWMPAENHPNLARIHPSGAATTGLAHGVAGPLALLATAHVAGWSVPGQAEGIDHAADWLLDWRRDDGTWPPSVTGDELDTAQPPSTPGRADAWCYGTPGISRSLHLAGLALDDPHLQAAAISAVDTMGSRKPAEWDVEGPTLCHGYAGFLQSAPDNHPVAGAVVEAISAYFDSSHRFGFQHRDQGQTHVEPGLLTGAAGVALALAEHQDLPTPGTPASWECLLNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVY2</accession>
    <name>D3PVY2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DegV family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5472</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5472"/>
    <dbReference type="EnsemblBacteria" id="ADD45103">
        <property type="protein sequence ID" value="ADD45103"/>
        <property type="gene ID" value="Snas_5472"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5472"/>
    <dbReference type="eggNOG" id="COG1307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048251_0_1_11"/>
    <dbReference type="OMA" id="MALGFCA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="326" mass="34587" checksum="63607363ECFADDD4" modified="2010-04-20" version="1">MPVAVVTDSTACLPPGAEDEYPLTIIPMRVTINGYSGAEGTEITTVDIARAFQERRVEVSTSRPAPGAVAEIYQRLLDDGATGVVSVHLSAALSGTYESAVLAAREFDGKVTVVDSANAGMGLGFCVLAASAAAKRGRGARFVADSASAASSATDTFFYVDTLEFLRRGGRISAAGALLGTALAVKPILHVESGEVKLRDKVRTSTRALARLEDLVVAAGRDGPVDLALHHLRSPERAEELAHRLRDRFGRQVREVFITEVGAVIAAHCGPGLLGAVVHRRVKKLSTTQKLSTGPQAPRSPRPNHARYTGHEYFHASPRTAGHSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVZ6</accession>
    <name>D3PVZ6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45117">
        <property type="protein sequence ID" value="ADD45117"/>
        <property type="gene ID" value="Snas_5486"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5486"/>
    <dbReference type="eggNOG" id="ENOG5030KTT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1110858_0_0_11"/>
    <dbReference type="OrthoDB" id="2125598at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="250" mass="26631" checksum="54208A9844ACACB8" modified="2010-04-20" version="1">MISKLGYVPKESRGDHAPEYFDTETVTAADRSKFRTRKRAKKASVVSRILAGVVALVVLGGIGFGIWFLAGSGADDKGNGLTYAALSKPCDKLDPAPMKDITGGSDVKATKDEVEKHAHSTEQFCEASFGKPGEGGSVAVNTQVFKRDAGAKNAYEDALDEAELNAEEATETGGGEQLIETVDGVGTKAYSNTRKAAKGSKTVDYTLVYYQDNAFIETRLSVYNGAASLSEVKGYTKAVAQKYMENWAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW78</accession>
    <name>D3PW78_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016806.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1531"/>
    <dbReference type="EnsemblBacteria" id="ADD41235">
        <property type="protein sequence ID" value="ADD41235"/>
        <property type="gene ID" value="Snas_1531"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1531"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_11"/>
    <dbReference type="OMA" id="WTNGANI"/>
    <dbReference type="OrthoDB" id="1209997at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="268" mass="27510" checksum="4FD0B98DC4FA9B78" modified="2010-04-20" version="1">MDLRLSDRVAVVTGASKGMGLAITATLLSEGAKVIAVSRKSSPELDALAGPRLVHVSADLTNPEAPASAIASAVEVFGGVDILVNNAGGPPPGTSLPRFGFLTPDDADWRDMFEFNLFSAVRAIRAAIPVMLGRGGGAIVNVSSTLARQPGAMNVDYSAAKAGLNAVTKSLSEEFGPQGIRVNTVSPGPVRTDWWTKDGGAADIIAASAGIDRDAVMDSAAPEMMRLTTGRLIDPQEVADAVALLVSPRSGSTTGAEYIVDAGALKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW98</accession>
    <name>D3PW98_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Type III effector Hrp-dependent outers</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_1552</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the four-carbon acid sugar kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016826.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1552"/>
    <dbReference type="EnsemblBacteria" id="ADD41255">
        <property type="protein sequence ID" value="ADD41255"/>
        <property type="gene ID" value="Snas_1552"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1552"/>
    <dbReference type="eggNOG" id="COG3395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029424_1_0_11"/>
    <dbReference type="OMA" id="CSVMTNK"/>
    <dbReference type="OrthoDB" id="771666at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037051">
        <property type="entry name" value="4-carb_acid_sugar_kinase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010737">
        <property type="entry name" value="DUF1537"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031475">
        <property type="entry name" value="NBD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042213">
        <property type="entry name" value="NBD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17042">
        <property type="entry name" value="NBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07005">
        <property type="entry name" value="SBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SBD_N" evidence="8">
        <location>
            <begin position="8"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="NBD_C" evidence="9">
        <location>
            <begin position="296"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="244"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD41255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="466" mass="48574" checksum="673767434D592980" modified="2010-04-20" version="1">MTEPPLVGAIADDVTGATDVAVAFRRNGLRTFLSFGVSPGLDVGAETVVVALKTRMIEPDAAVAQSRAAWDWLRRLGARRVYFKYCSTFDSTSRGNIGPVLDALADATGAATVVTTPSSPEHGRTQYEGHLFVGDVLLAESHMRDHPVTPMRDSNLPRLLRAQTRETVGLLGYRDVLDGEAAIARRLAAARADGVRYLLADAVTDADLRRLGRVVANEPLMAGAAGLAGGIAAALAEKRGEAAAPLAARSPGETAAPLADRRDEPAAELAAGGPREAISAAPLEHQAPPPPTGPAVVLSGSCSKRTLEQIAYLRQHDRPAFFLDVSATPDAAALADTALAWYDTLPADAAPLIYSSVEPERLHHIQQRIGVERAAAILEDATGRIAHGLAARGVRRFIAAGGETSGAVVAALRVDGGLIGTEAARGVPWIHSPTGDLSLLLKSGNFGEPDLLARASASGGDDVPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWK9</accession>
    <name>D3PWK9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018802.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3569"/>
    <dbReference type="EnsemblBacteria" id="ADD43231">
        <property type="protein sequence ID" value="ADD43231"/>
        <property type="gene ID" value="Snas_3569"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3569"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063440_10_0_11"/>
    <dbReference type="OMA" id="PPRHMYR"/>
    <dbReference type="OrthoDB" id="1706427at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="36"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="109" mass="12137" checksum="BF2E73D0D3F1E6C4" modified="2010-04-20" version="1">MVERLKLTTTVVRVLTCFIEDVDADRYGMDLMRDSDLASGTLYPILNRLEEAGWLTASWEKVEAGATARPARRYYRLTPDGAKAARTELAAVHERLSKALGPLGKPRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWN2</accession>
    <name>D3PWN2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Magnesium chelatase</fullName>
            <ecNumber evidence="2">6.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.6.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018825.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3594"/>
    <dbReference type="EnsemblBacteria" id="ADD43254">
        <property type="protein sequence ID" value="ADD43254"/>
        <property type="gene ID" value="Snas_3594"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3594"/>
    <dbReference type="eggNOG" id="COG1239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016684_0_1_11"/>
    <dbReference type="OMA" id="RISAVCG"/>
    <dbReference type="OrthoDB" id="895310at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="31"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="33686" checksum="E7B5C03007078CEE" modified="2010-04-20" version="1">MTDDIQVLPYSYVVGQDALKHALEISYVSRGSGGVLIAGERGTAKSTTVRAFTRMVNDRLPVTLPINATDDRVLGGWRIEELMRGEARPQPGLLETANDGVLYIDEVNLLDDHLVNVILDVASTGILVVQREGRDEQIPVSFTLVGTMNPEEGGLRPQLLDRFGMAVPVSTETDVGRRAEILSTVLRFDVEGALPSSTWLSQGTRNDQARREALNAARDRVSDSVVSDKIVDLCAQVATEFKATGHRSEIVMVNAARAETALDGRTAVEPRDVAAVAPFALLHRRPEAAFAEDLSWTAADQKLLDALTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWR4</accession>
    <name>D3PWR4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018857.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3626"/>
    <dbReference type="EnsemblBacteria" id="ADD43286">
        <property type="protein sequence ID" value="ADD43286"/>
        <property type="gene ID" value="Snas_3626"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3626"/>
    <dbReference type="HOGENOM" id="CLU_2332274_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="98" mass="10575" checksum="D6D30B636FC54AF4" modified="2010-04-20" version="1">MTTHHDIDAHYDTDDPVLLADLMARVDDLDSHQLADYAIGRGLTPPGYVPGHYYSIDLAWPPGADDGDGVLLWSTSRLGDDGVPADEDDAAVWDSAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWV1</accession>
    <name>D3PWV1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5544"/>
    <dbReference type="EnsemblBacteria" id="ADD45175">
        <property type="protein sequence ID" value="ADD45175"/>
        <property type="gene ID" value="Snas_5544"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5544"/>
    <dbReference type="eggNOG" id="COG0662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_590391_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="168"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="463" mass="52108" checksum="310E4F9AE4FA8FB2" modified="2010-04-20" version="1">MFLTHPPSALIDGSPRLRLRSPPTYWRCEPSWVWQARPLTDHLLWHVHDGAGELRLDDRHVRLRPGFCAVFAPGDAPVATHDPRHPLLVFGMHFTATGFDGDLVPEQRWCRLWDQEFAVRLARHCDYAHRRGDDLGQRQAVLGLEQFLCLLWDNVTRPAPGPGDAAVEDIARAVRQEPSRDWTVATLAKRANLSRAQFTRRFTAHTGYSPARYVIRARLDRARQLLTETNMSVGQVAATLGYPDVGYFSRQYKVHTGSSPSRDRGGGETSVDWLMRVPTVPLSPNIQGRSDYRSRSVITEYQAPNGFATIPRQRSLREHPLIAALLSLELDPRDYVIFGSGPLLAHGLRADVADLDVVARGRAWHRALRMSGYSIDLGPHSFELMLRFFGGGVEISAYWTDTSWDVDALIDTAEIIDGLRFAALRDVLEYKRTLDRAKDRADVAALERHLSTAEELEPVLCAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D3PX98</accession>
    <name>D3PX98_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1659</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1659"/>
    <dbReference type="EnsemblBacteria" id="ADD41361">
        <property type="protein sequence ID" value="ADD41361"/>
        <property type="gene ID" value="Snas_1659"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1659"/>
    <dbReference type="HOGENOM" id="CLU_2977083_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="58" mass="6707" checksum="8B6146B417003768" modified="2010-04-20" version="1">MSAAHEESDIRQYWDSMSVSEAECRTERRRRDALEALRADYLALETDAKYVFKAHGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXD7</accession>
    <name>D3PXD7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1701"/>
    <dbReference type="EnsemblBacteria" id="ADD41400">
        <property type="protein sequence ID" value="ADD41400"/>
        <property type="gene ID" value="Snas_1701"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1701"/>
    <dbReference type="HOGENOM" id="CLU_069624_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="243" mass="26293" checksum="BDA14EE9FF2A97E7" modified="2010-04-20" version="1">MNLLAELTGRLSDQWLRWQGLPGLMFVCVVLVGNHLGYAHAIDVGEAGRFLNRQSSWLATLTTIQVIAVVIALVITSAVAGLTATLAGVGVEAVVLGGKRPARLTGELTAMEEHFRNIYLLDVATAWPHLWLRFPAEHREQVTGNRAGIRHAATLVGWGILTSAVSVIWPIAWIAVLGLVLVGIHLMRQSISAYSQTVAVLMMHHAPELASQLGFENSGRLDRAVGSKLQYYLQGDEPPAPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXP1</accession>
    <name>D3PXP1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3714</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018942.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3714"/>
    <dbReference type="EnsemblBacteria" id="ADD43371">
        <property type="protein sequence ID" value="ADD43371"/>
        <property type="gene ID" value="Snas_3714"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3714"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="MSNRVQA"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="148"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="225" mass="24384" checksum="D28E0D5B62060E5C" modified="2010-04-20" version="1">MIRTLIVDDDALVRLGLCDLLDDEPDITVVAQAADGKSAVAQAERHRVDVALMDVRMPGMDGIAATARLRALPEPAQVIALTTFDLDEYVYDMIAAGAAGFLLKDTDPGEIIRAIRVVAAGDAMLHPAAARRLIERYHRAARPRATAVRHRVDRLTPRETDVLRHLALGATNAEIAASLSMRESTVKAHVTRILATLDVTNRVQAALCARDAELPPPPRGGRRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXT2</accession>
    <name>D3PXT2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018983.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3755"/>
    <dbReference type="EnsemblBacteria" id="ADD43412">
        <property type="protein sequence ID" value="ADD43412"/>
        <property type="gene ID" value="Snas_3755"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3755"/>
    <dbReference type="eggNOG" id="COG0402">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012358_2_3_11"/>
    <dbReference type="OMA" id="RVFWSYA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="54"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="419" mass="43866" checksum="76EC744D8FFDB65D" modified="2010-04-20" version="1">MTLVLIRNAHLIDTVPTVRVLRETDLLIDGDSIREVGRGLSAPGATVIDAAGRIVLPGLIDTHRHTWQTALRGMLRVGTLGDYLARFLQDLGPRYTPEDVHIGNLAGAVDALDAGITTLLDWSHIQNSPEHTDAAVAGLRESGIRGVFAHSFGLPLKPGPHSPDARRVRETHFASSDGLLDMALGIAGPQFGDPDIAADDIRLARELGCRVTVHIHSSAGVETLDELGMLGPDLTFVHANGLDAAAMRRLADTGAAVSVSPQVEAQLGMGAPLIAPLLALGVPTSLSVDTVTSAAGDLFTQMRLALSFARLADPAVSAADILRMATVDGARALGLDDRIGSLRVGSRADLVMLGDRLPVHDPVGTVVAEAERGDVDTVLVDGRVVKRGGQLTAVDTAGIAERLAASAERLLGRPGDETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY10</accession>
    <name>D3PY10_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Folate-binding protein YgfZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5709</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020910.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5709"/>
    <dbReference type="EnsemblBacteria" id="ADD45339">
        <property type="protein sequence ID" value="ADD45339"/>
        <property type="gene ID" value="Snas_5709"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5709"/>
    <dbReference type="eggNOG" id="COG0354">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_6_0_11"/>
    <dbReference type="OMA" id="RHHELGP"/>
    <dbReference type="OrthoDB" id="1984573at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045179">
        <property type="entry name" value="YgfZ/GcvT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017703">
        <property type="entry name" value="YgfZ/GcvT_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602">
        <property type="entry name" value="PTHR22602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03317">
        <property type="entry name" value="ygfZ_signature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="GCV_T" evidence="3">
        <location>
            <begin position="17"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD45339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="344" mass="37375" checksum="0B8144947B014D3F" modified="2010-04-20" version="1">MNSILLSRPGAVRELEASTVPWHYGDPLREQKHLDSTGAVVERDRDLLVLSGPERLSWLHSITTQHLTELGDEQGTELLVLSPNGHIEHHAAVFSLGDKLWLDTAPGQGAALRDFLAKMRFFAQVEIEEVTDFALLSVTGPSDLAEPDTLEIPDAKFAAGSVPPRPSSIFAGRARPDGGWERRTDTVGRPTVDILVPRDQLDETIAALGLPLAGTWAYDTLRIPQGLPAFGVDTDHRTIPHEVVSLLVTAVHLDKGCYRGQETVARVHNLGKPPRATSILHLDGTEEQPPKPGDEVMLDGRAVGRVGTAGRHYEDGMIALALLRRNVRDKTDAKLMIGDSAAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY45</accession>
    <name>D3PY45_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5744</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020945.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5744"/>
    <dbReference type="EnsemblBacteria" id="ADD45374">
        <property type="protein sequence ID" value="ADD45374"/>
        <property type="gene ID" value="Snas_5744"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5744"/>
    <dbReference type="eggNOG" id="COG4941">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035311_1_0_11"/>
    <dbReference type="OMA" id="RYEDTDW"/>
    <dbReference type="OrthoDB" id="1469807at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="21"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="116"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="438" mass="48280" checksum="FC1A23DAAF8ECA83" modified="2010-04-20" version="1">MTGTDTAPTIETVFRIEAARIIAGVTRVVRDIGIAEELAQDALVAALEQWPRSGVPDKPGAWLMATAKHRAIDLVRRKETYARKLAEVGRTLEDVPPPPEPGDPEDIDDDLLRLIFTSCHPVLSTQARIALTLRLLGGLTTEEIARAYLSSEPTVAQRIVRAKRTLAKAGVPFEVPYGEDRGARLSSVLEVIYLIFNEGYSATSGENLVRPVLCEDALRLARVLQGLMPDEPEVHGLAALLEFQGSRLPTRTGPDGELVLLADQDRSKWDRLLIRRGMAALRRAGVGEYSLQAAIAACHARANRYADTDWTMIASLYERLMALTPSPVVELNRAVAVAMAYGPQAGLEIVDALAELGSLSDYHLLPSVRGDLLERLGRTAEARAEFERAAALTGNARERDLLLARAERIRKLPLPPMFVLSPLPNRFRRRRFEVQPRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY52</accession>
    <name>D3PY52_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_5751</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020952.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5751"/>
    <dbReference type="EnsemblBacteria" id="ADD45381">
        <property type="protein sequence ID" value="ADD45381"/>
        <property type="gene ID" value="Snas_5751"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5751"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_61_2_11"/>
    <dbReference type="OMA" id="MGTSEFM"/>
    <dbReference type="OrthoDB" id="1384345at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="4"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD45381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="395" mass="39785" checksum="412BF79B08B3DD2B" modified="2010-04-20" version="1">MPLPLYLLALAVFAMGTSEFMLAGLLPDIAASLDVSVATAGLLTSAFAVGMVVGAPLMAALARRWPARHTLLAFIAASAATHIIAALTSNFTILLLTRILAALANAGFLAVALTTAATLVAADRKGRALAVLLSGTTAATIAGVPGGALLGTLLDWRATFWAIAILCLPAALGILKGIPTRSIHSESDTAPGLRSELAQLARPRLILVMSLGALVNAATFGTFMFLAPIVTDTASLPDLWISVVLVVFGLGSFLGVNLAGRLSDARPGLVIAIAGPLQLLGWIALALLATEPLALLALTFTQGVLSFALGSTLIARVLYAASGAPTMGGSYATAALNVGAALGPIAAGATLTAGHGDLGPVWASTVLVGLALAIALVSRRALTSQAPERLSSAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYD1</accession>
    <name>D3PYD1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_1802</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017069.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1802"/>
    <dbReference type="EnsemblBacteria" id="ADD41498">
        <property type="protein sequence ID" value="ADD41498"/>
        <property type="gene ID" value="Snas_1802"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1802"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_3_1_11"/>
    <dbReference type="OMA" id="YSAFSRM"/>
    <dbReference type="OrthoDB" id="1891092at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="9">
        <location>
            <begin position="18"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD41498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="265" mass="28903" checksum="10D09102A24739EF" modified="2010-04-20" version="1">MTVLAVQLFRVRLGRSGAMVERNYTAHRRAWLLIISGVFEPLFYLFGLGIGVGALIGTIPLPDGREIDYATFVAPAMLANAAMMAAIAETTFNVFGKLKWAKLYDGILATPMRPMEIMMGETMWALIRGAIYVIAFIAVMAAMGMIASAWAILALPAAILIGLSFVGIGLTLSTVFKSWTDFDWLISIIFVMFLFSGTFTPVETYPEALRWLVYLSPLYHGIELVRGLTLGLPEWGLLGHAAFLAAVGGVGIAVAARRMGRLLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYI7</accession>
    <name>D3PYI7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017125.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1858"/>
    <dbReference type="EnsemblBacteria" id="ADD41554">
        <property type="protein sequence ID" value="ADD41554"/>
        <property type="gene ID" value="Snas_1858"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1858"/>
    <dbReference type="HOGENOM" id="CLU_1651094_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045596">
        <property type="entry name" value="DUF6459"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20060">
        <property type="entry name" value="DUF6459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="160" mass="17905" checksum="5DBA72A81F5FFA5C" modified="2010-04-20" version="1">MTERQTDDQTGRLSSKLRLIPLTSVMPILAARPPARPTELQRRAPEPTVSARDLRRAAESLVELCAQVLRGRHPLSAIRRVADPRAFAQFTTLFRRTRPLRPNAEPVSLRLSHTATDPSGALTMVALMRAGDRVRAVSLCARPRSPRGWQLTLCQLIENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYU3</accession>
    <name>D3PYU3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019097.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3871"/>
    <dbReference type="EnsemblBacteria" id="ADD43526">
        <property type="protein sequence ID" value="ADD43526"/>
        <property type="gene ID" value="Snas_3871"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3871"/>
    <dbReference type="eggNOG" id="COG0718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2182346_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="109" mass="11912" checksum="B8A6D08F00B86CD0" modified="2010-04-20" version="1">MTVNIEDDAMAEVDPHQALAESEAADRAYLRKLDEHVVTARDANGLVTVTSFATGEVKDVEISARRYAALSREDLADAVLEAWRNARTEANAAAKRLHESFVLKQGGET</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYU4</accession>
    <name>D3PYU4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019098.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3872"/>
    <dbReference type="EnsemblBacteria" id="ADD43527">
        <property type="protein sequence ID" value="ADD43527"/>
        <property type="gene ID" value="Snas_3872"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3872"/>
    <dbReference type="eggNOG" id="ENOG5034AYS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_518657_0_0_11"/>
    <dbReference type="OMA" id="IMPERSE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038332">
        <property type="entry name" value="PPE_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="555" mass="57270" checksum="B7BBB06C5418689D" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZD6</accession>
    <name>D3PZD6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">D-malate dehydrogenase (decarboxylating)</fullName>
            <ecNumber evidence="5">1.1.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_1914</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-malate + NAD(+) = CO2 + NADH + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:18365"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15588"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.83"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.83" evidence="5"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017181.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1914"/>
    <dbReference type="EnsemblBacteria" id="ADD41610">
        <property type="protein sequence ID" value="ADD41610"/>
        <property type="gene ID" value="Snas_1914"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1914"/>
    <dbReference type="eggNOG" id="COG0473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031953_0_1_11"/>
    <dbReference type="OMA" id="KLFRQPS"/>
    <dbReference type="OrthoDB" id="1551125at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046553">
        <property type="term" value="F:D-malate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011829">
        <property type="entry name" value="TTC_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02089">
        <property type="entry name" value="TTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="7">
        <location>
            <begin position="5"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD41610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="352" mass="37571" checksum="4D3523CB29D931B8" modified="2010-04-20" version="1">MRTHRIASIPGDGIGVDVTVEARKVLDRAGQRHGFTLEWTEFDWSCERYARTGAMMPEDGVERLSAFDGIFLGAVGFPGVPDHVSLWGLLIPVRRAFSQYVNLRPVRLLPGVTSALAGRSAEELEMVIVRENSEGEYSTIGGRHNTGRPDEFVLQESVFTRVGVERIIRYAFQVAGSRSGRVCSATKSNGLVHSMPYWDEIFAEVAAEYPDIHSEQCHVDALAARMVQQPDRLDVVVGSNLFGDILSDLAAAVTGGLGMAPSGNINPPGEYPSMFEAVHGSAPDIAGKGIANPVAQVLAGAMMLEHLGERDAARTVETAVSDVLAERAVVTPDLGGSATTSELGSEIAAALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZF3</accession>
    <name>D3PZF3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017198.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1931"/>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41627">
        <property type="protein sequence ID" value="ADD41627"/>
        <property type="gene ID" value="Snas_1931"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1931"/>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008392_5_3_11"/>
    <dbReference type="OMA" id="EMGLPIW"/>
    <dbReference type="OrthoDB" id="949956at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_3" evidence="2">
        <location>
            <begin position="29"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="490" mass="51419" checksum="0D1FF107F2DBE78C" modified="2010-04-20" version="1">MPDRQELRQLALRTLIPGFSGTTAPRWALDLLDEGLGGYCLFAHNVADPQQLSELNSSLRQANKDVLIAIDEEGGDVTRLHSASGSHYPGNAALGAVDDPELTAAVHQSMGAELAAAGVTVDFAPSVDVNVEDDNPVIGTRSFGRDPQGVARHAVAAVRGLHRAGIIACAKHFPGHGATVVDSHFEVPTVDIPLSELRERELVPFRAVIDSGIELIMSGHIRVPELTGDAPGTMSRAAMHDLLRGELGFDGAIVTDAMEMRGASGAIGMPEAVVRAIAAGCDLICTGGELQKRGPMTEVVNAVADAVATAVIDGRLPYERLADAVRRGDVLREWQRENRGSRAPHALGLAAARRAITVEGTVPALSNPLIVQIDSTANIAVGESQWGVTPLLAKHLPHAQIRNVTPENASVAQISALADNRPVIVVARDTHRRPASKGFVEGLAASGHDVVLVEMGWPAAWRPEGVAAYVASFGAAAVNAEATVEVLLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZS3</accession>
    <name>D3PZS3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidoglycan-binding domain 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3958</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019181.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43610">
        <property type="protein sequence ID" value="ADD43610"/>
        <property type="gene ID" value="Snas_3958"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3958"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1414406_0_0_11"/>
    <dbReference type="OrthoDB" id="2025306at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049404" evidence="1">
        <location>
            <begin position="29"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="80"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="192" mass="20632" checksum="D39AC42FF028BB74" modified="2010-04-20" version="1">MASRKWTIAAVAAATIAVAGGTAGWAAADSVDTKASTYVDGLNKVTDDWNDHYRELGGSLCDGCENSDNTDLVVLWQSVLVVDGFLATEDPIDGYFGPDTKRATAMWQDHFGVKQTGKVNAATWAEASSHLSETDGTVYYAKEGGGEVRFTRHEDGSYTFNKVLIPGGEELVNNGGKRIEFYKRTVKLAPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZU1</accession>
    <name>D3PZU1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019199.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3976"/>
    <dbReference type="EnsemblBacteria" id="ADD43628">
        <property type="protein sequence ID" value="ADD43628"/>
        <property type="gene ID" value="Snas_3976"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3976"/>
    <dbReference type="HOGENOM" id="CLU_1958242_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="128" mass="13069" checksum="57CC2132E47158D4" modified="2010-04-20" version="1">MTIQINADTVNTMAGSAEEAASLVDGTTQTLSDGGAVASASGMDGFATADVVGDVWARWLSKSAACRDSVEYFAEALRATASTLATTDADNAEFVYPAGSPVVADGPPWTRPQPYTDDRPPVGPPDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZW5</accession>
    <name>D3PZW5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019223.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4000"/>
    <dbReference type="EnsemblBacteria" id="ADD43652">
        <property type="protein sequence ID" value="ADD43652"/>
        <property type="gene ID" value="Snas_4000"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4000"/>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016902_4_4_11"/>
    <dbReference type="OMA" id="AHPSPGW"/>
    <dbReference type="OrthoDB" id="1714699at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="18"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="312" mass="33561" checksum="CB98BCC5D0128E4C" modified="2010-04-20" version="1">MSNRESREVLVPDGLDGLRIDQVISRLFGLSRTVAAELVSAGEVTVDGQECMKSTRVAAGGQLSVLLPEPPKPASAPEPELVEGLAVIYSDDDIAVVDKPVGVAAHSSPGWNGPTVVAGLAAAGHRISVHGPPERQGIVHRLDVGTSGLMAVAKSERAYSALKRAFKQREVDKRYRTVIQGHPDPLRGTIDAPIARHPGHDFKFAVRAGGRASITHYDTLEAFPAASLLDVQLETGRTHQIRVHFSALRHPCVGDLIYGADPTLASKLGLTRQWLHAYRLGFIHPGTAKPVEFRCEDPPDLAHALRVLRGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D3PZX5</accession>
    <name>D3PZX5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">UDP-N-acetylmuramate--L-alanine ligase</fullName>
            <ecNumber evidence="4 11">6.3.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">UDP-N-acetylmuramoyl-L-alanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">murC</name>
        <name evidence="15" type="ordered locus">Snas_4010</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine</text>
            <dbReference type="Rhea" id="RHEA:23372"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MurCDEF family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.8" evidence="4 11"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019233.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4010"/>
    <dbReference type="EnsemblBacteria" id="ADD43662">
        <property type="protein sequence ID" value="ADD43662"/>
        <property type="gene ID" value="Snas_4010"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4010"/>
    <dbReference type="eggNOG" id="COG0773">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028104_2_2_11"/>
    <dbReference type="OMA" id="DITYQLR"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008763">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00046">
        <property type="entry name" value="MurC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005758">
        <property type="entry name" value="UDP-N-AcMur_Ala_ligase_MurC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01082">
        <property type="entry name" value="murC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 11" id="KW-0133">Cell shape</keyword>
    <keyword evidence="10 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="12">
        <location>
            <begin position="16"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="14">
        <location>
            <begin position="119"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="13">
        <location>
            <begin position="321"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="121"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ADD43662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="473" mass="50707" checksum="2D0EDB6FE318C38F" modified="2010-04-20" version="1">MKSPIDEGITAEDLGHVLFMGVGGVGMSGLARLYATRGLSVSGSELHEWPSLAELERLGVTVHREHRASNLDGIDTLVRSTVHPDDHLEIAEARRRGIRVYHRSEALAAAMTGKKSIVVSGTHGKTTTTGMITDMLAAAGLNPSFVNGGESAADGRSGAHGSGELFVTEADESDRSFLRYRPFVSILTNIDVDHLNTYGTIEELVEGFAEFLRGTDPSGSIIVCADDERAAAVGKRLAAEGRTVVSYGTDAEADLRIGEITIDASGARYTASYRGRDLGSFFVTVPGRHLALNSAAALLAGLLLDVDVEELRTGLAAFTGVRRRFELTGTVAGVRVYDEYAYHPTAMNAALSTLKTIAEPGRLIVVFQPYRVYRTRDLRTEIAEALALADLAVVMEVFGPGEELADDDGGRPLVEAIPLPPQAKRFVPQWSDVPGAVREWAREGDTVVTMGAPPISLMPADILRELLPPESTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q000</accession>
    <name>D3Q000_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_5901</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021100.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5901"/>
    <dbReference type="EnsemblBacteria" id="ADD45529">
        <property type="protein sequence ID" value="ADD45529"/>
        <property type="gene ID" value="Snas_5901"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5901"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_9_3_11"/>
    <dbReference type="OMA" id="KGRFFTW"/>
    <dbReference type="OrthoDB" id="1992113at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="47"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="146"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD45529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="206" mass="23140" checksum="46A3817684F165F1" modified="2010-04-20" version="1">MSYGTGGASHRQEQPRSPFAPVPDNPISDEALLQRAALGDEDAFTVLYDRLSPRVYGLCLRVLRDPAQAEEVAQDVLVELWRTAARFDPSQGSALTWVATLTHRRAVDRVRSTQASRDREHRSAVSNVEPEYDQVAEAVAQRLDMRQLRRCLKTLTELQHQAVTMAYYGGHSYRQVANLLGAAVPTVKSRIRDGLIRLRDCLEVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q054</accession>
    <name>D3Q054_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021154.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5956"/>
    <dbReference type="EnsemblBacteria" id="ADD45583">
        <property type="protein sequence ID" value="ADD45583"/>
        <property type="gene ID" value="Snas_5956"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5956"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_1_2_11"/>
    <dbReference type="OMA" id="RRTYDEW"/>
    <dbReference type="OrthoDB" id="1306955at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="2"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="188" mass="20774" checksum="7AECCE0A2F48A2EE" modified="2010-04-20" version="1">MRKLIVQQWVTLDNIAAEEDGGLSYVTAEPFSEKSDPAFKNTVMGFVDSVDTLVLGANTYHQTKDYWPHAEEQGEYGRKLNDLTKFVASSKLEAAPWGDFPAATVTRDAVATVRELKEQDGKDIWLWGSLTLMRSLLAAGVVDEMTLLVCPATRGRGTRVFEGTHDLKLITATGFDNGLAIMRYAINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q080</accession>
    <name>D3Q080_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Proteinase inhibitor I16 subtilisin-type inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Snas_5983</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the protease inhibitor I16 (SSI) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021180.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5983"/>
    <dbReference type="EnsemblBacteria" id="ADD45609">
        <property type="protein sequence ID" value="ADD45609"/>
        <property type="gene ID" value="Snas_5983"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5983"/>
    <dbReference type="eggNOG" id="ENOG50345GU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121949_0_1_11"/>
    <dbReference type="OMA" id="CDPPQGH"/>
    <dbReference type="OrthoDB" id="2050426at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000691">
        <property type="entry name" value="Prot_inh_I16_SSI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020054">
        <property type="entry name" value="Prot_inh_SSI_I16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023549">
        <property type="entry name" value="Subtilisin_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036819">
        <property type="entry name" value="Subtilisin_inhibitor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00720">
        <property type="entry name" value="SSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00294">
        <property type="entry name" value="SSBTLNINHBTR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55399">
        <property type="entry name" value="SSF55399"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00999">
        <property type="entry name" value="SSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 8" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 8" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049417" evidence="9">
        <location>
            <begin position="26"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="SSI" evidence="10">
        <location>
            <begin position="50"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ADD45609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="134" mass="13617" checksum="921ED10DA941DA8A" modified="2010-04-20" version="1">MTRTATRLAGAVVLTAGLLAVPAAASASAVDTVVEGHYSLKLTPKQGASISYDLSCTPDGGSHPNTAAACEDLDAADGHVTDIPAQSGPCTKEFAPVVAIAKGVWDGGERSYEQEFSNECEAVARTGGAVFDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0K7</accession>
    <name>D3Q0K7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2048</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017314.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2048"/>
    <dbReference type="EnsemblBacteria" id="ADD41743">
        <property type="protein sequence ID" value="ADD41743"/>
        <property type="gene ID" value="Snas_2048"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2048"/>
    <dbReference type="eggNOG" id="COG1121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_11"/>
    <dbReference type="OMA" id="GHDHVHP"/>
    <dbReference type="OrthoDB" id="1721927at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="247" mass="25618" checksum="690D0477D360F0DC" modified="2010-04-20" version="1">MSMNIVEVDKAVVGYADRRVLHGVDVTVQPGQAVALLGANGSGKSTLVRTALGLVPLSAGKVTLFGTPLKAFKQWRRIGYVPQRLGAGGGVPATVGEVVAAGRLARRRIPWPANATDRRVVAEAIEAVGLSDRVKDSVSTLSGGQQQRVLIARALATEPELLVMDEPTSGVDAANTELLAELLGQRLDAGAAILLVAHELGPLAPLIDRAVVLGGGRVVHDGPVPANGDTAGEHCETPVHQNLWSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q0W5</accession>
    <name>D3Q0W5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Monooxygenase FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019286.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4063"/>
    <dbReference type="EnsemblBacteria" id="ADD43715">
        <property type="protein sequence ID" value="ADD43715"/>
        <property type="gene ID" value="Snas_4063"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4063"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_1_0_11"/>
    <dbReference type="OMA" id="WARWYNA"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="2">
        <location>
            <begin position="5"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="402" mass="43251" checksum="29A90E5B7D80BE08" modified="2010-04-20" version="1">MPHERVLISGAGIAGITLAHWLHHHGFSPTVVERAPAPRAGGYKVDIRGAALSVVERMGLTDAIRAACTDIQGGSVVTASGKRVASMDGDSFGGREHEDSELPRGELGRLLYEATEKKADFRFGDSITALDQTGDDVEVTFASGTTERFDLVVGADGLHSATRALAFGPEDQYVRDLGYYVSVYTVPNHLNLDREELTYVGPGRTALMYSTAGDPNARAMFLWSSPSLEYDRGDANAQRELLRSAYADEGWEVPTLLEAAETTPDFYFDTLSQVHMDHWFTGKVALVGDAAHCASAASGQGTSLALVGGYVLAGELSRAKDPTAAFAAYEQRMRGFAETNQALGPANIKRMVLRGKGQIRVAMTMLALMSRMPGKERMMARVAATIHKAATAIDLPDYEAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q112</accession>
    <name>D3Q112_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Proline racemase</fullName>
            <ecNumber evidence="2">5.1.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proline racemase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019333.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4111"/>
    <dbReference type="EnsemblBacteria" id="ADD43762">
        <property type="protein sequence ID" value="ADD43762"/>
        <property type="gene ID" value="Snas_4111"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4111"/>
    <dbReference type="eggNOG" id="COG3938">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036729_0_0_11"/>
    <dbReference type="OMA" id="SHVLWTG"/>
    <dbReference type="OrthoDB" id="559014at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018112">
        <property type="term" value="F:proline racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008794">
        <property type="entry name" value="Pro_racemase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33442">
        <property type="entry name" value="PTHR33442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05544">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029792">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00028">
        <property type="entry name" value="Proline_Racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="333" mass="35422" checksum="FA2CCED39EB4FEF4" modified="2010-04-20" version="1">MRASRYFSAVDSHTEGMPTRVVTGGVGPIPGDTMAARREYFIENLDHIREFFVNEPRGHAAASGAILQPPTRPDADWGVLYIEVSGLLPMCGHGTIGVATVLVETGMVEVTEPVTIVRLDTPAGLVTVEVTVDNGRAASAKFQNVPAFSVELDATVSVPGIGDVTYDMAYGGNFYAILPIEQLGIGFDKAEKDRILAAGMTIMDAINAQNRPAHPKDPGIAGCKHVQFTAPGRDGADSRNAMVIHPGWFDRSPCGTGTCARMAQLHARGALDLNTPFVNESLLGTRFTGELIDTTDIAGQPAVIPTVSGRAWITGMAQYLLDPEDPFPSGFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q132</accession>
    <name>D3Q132_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Roadblock/LC7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019353.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4131"/>
    <dbReference type="EnsemblBacteria" id="ADD43782">
        <property type="protein sequence ID" value="ADD43782"/>
        <property type="gene ID" value="Snas_4131"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4131"/>
    <dbReference type="eggNOG" id="COG2018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094585_0_1_11"/>
    <dbReference type="OrthoDB" id="1635683at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Robl_LC7" evidence="1">
        <location>
            <begin position="7"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="136" mass="14188" checksum="13269F73BAF34FDB" modified="2010-04-20" version="1">MNTQNLDYLLNDFIDRVPDVTHVLTVSADGLLIACNDELPEDDADRLAAIASGLVSLLAGAARALQADPVISCMAELYGGYMFSMSIPGGASLLALASYDCDIGQVGHELADLINKIGPSISPEARGQVSTANHGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1B9</accession>
    <name>D3Q1B9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6075"/>
    <dbReference type="EnsemblBacteria" id="ADD45699">
        <property type="protein sequence ID" value="ADD45699"/>
        <property type="gene ID" value="Snas_6075"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6075"/>
    <dbReference type="HOGENOM" id="CLU_609576_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="449" mass="49390" checksum="57F5AEEAC78848E4" modified="2010-04-20" version="1">MSKIQGADDVPATRRGPASQRRYRLTQVANVVAGLACGLITYAVNADLQLSLALGVIVTMGLLIVEYTAVTNSLMRVVHATNDRLICLGADLSKQDGLAAALAHLRGSAREGGNLAHTINRVHEAVPNIPVPLFGVVDDLLGQAARALETGHIVLGGSSSSLGSHLVRTFERDVFCTSFHPLDFWLTPYGRNYQAEIRDRLRELAKTGEVTFRRVFIVRGEVAEELRRQPYRGVIEEQLSAGIDVRITYEEDLPADLCVDFGIWDGELEVELECDEQRRIIARHYRYSHEHLAAAQRRAERLWDRSIAYADFLTRLPGCSQLPYRVHHLVPVAAAEHRGVDQQQMQLVQRNPVSPAFGQRPHLVVRRHDPVQVRRPAPQVQQCDVGLAVAAVGGGVDEPGPVTSPVDVAGPQVAVQSRHRFRRWRQLFDAGDDGLDGGDVGGRQGAVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1G5</accession>
    <name>D3Q1G5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Membrane dipeptidase</fullName>
            <ecNumber evidence="1">3.4.13.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.13.19" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021316.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6121"/>
    <dbReference type="EnsemblBacteria" id="ADD45745">
        <property type="protein sequence ID" value="ADD45745"/>
        <property type="gene ID" value="Snas_6121"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6121"/>
    <dbReference type="eggNOG" id="COG2355">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031404_4_2_11"/>
    <dbReference type="OMA" id="CDHPRNI"/>
    <dbReference type="OrthoDB" id="1145595at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01301">
        <property type="entry name" value="rDP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="PTHR10443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="402" mass="43344" checksum="FB99762B9841E8F6" modified="2010-04-20" version="1">MSTTASARAGALLATAPVIDGHNDLLIRMRGKVRYDFDAIDIAVDQTEHGLHTDIPRMRAGGMGGQFWSVFVPVSLQGEAAVTATLEQIDGAHEMIGRYDDLALATTADEIDKAFSDGRIASLLGAEGGHSIADSLGTLRMMYRLGVRYMTLTHTSNTAWADSATDAPVVGGLSEFGREVVREMNRLGMLVDISHVAPSTMHAALDVSEAPAFFSHSNALALCSHPRNVPDDVLRRVKDTQGIVMATFVPGFLNEACKEWMDALEAYDDKAQLAVAEDANEAGYEERKARREAWFAANPCPGASVSDVADHIDHIREIAGVDCVGIGGDMDGIGATPEQLNDVTGYPNLIGELASRSWSDDDLAKLTRRNVIRVLRETERVAQVARQQRGPSNKTIEQLDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1H1</accession>
    <name>D3Q1H1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6127</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6127"/>
    <dbReference type="EnsemblBacteria" id="ADD45751">
        <property type="protein sequence ID" value="ADD45751"/>
        <property type="gene ID" value="Snas_6127"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6127"/>
    <dbReference type="eggNOG" id="COG3246">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065536_2_0_11"/>
    <dbReference type="OMA" id="VPEYEIF"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019475">
        <property type="term" value="P:L-lysine catabolic process to acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008567">
        <property type="entry name" value="KCE_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37418">
        <property type="entry name" value="PTHR37418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05853">
        <property type="entry name" value="BKACE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="281" mass="29873" checksum="5EECECD06253E506" modified="2010-04-20" version="1">MLTSMTSTLITVAPTGAESSKADVPALPVTLDELVATAGDCEAAGASVIHVHIRDAEAQPTLDLGRLKDTVAALRESTNLIVQLSTGGAVTDPEEHRLRVLEAAPDMASCTMGTVNFGDDVFMNRWEFIVELHQRMRDRRIVPEYEIFDVGHLTSLERLLNQHGLPHGEHVHVDFVLGVPGGAPGDASTVTAFAEATRRHLPPGSTFSATGIGRGTLPVMFASLAHGGHLRVGMEDTVSYARRVPVDSNAQLVARAADAALLAQRPAMPVADARKLLNITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q1L5</accession>
    <name>D3Q1L5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_0143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015434.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD39863">
        <property type="protein sequence ID" value="ADD39863"/>
        <property type="gene ID" value="Snas_0143"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0143"/>
    <dbReference type="HOGENOM" id="CLU_2036604_0_0_11"/>
    <dbReference type="OrthoDB" id="1660095at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD39863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="121" mass="13092" checksum="864DEB2D0C6CB65C" modified="2010-04-20" version="1">MVSRPGEDNAVPGLPEEWGRIVIPDDASDLEELADEVRFELGITEDPVEERRQRRLPFIVVAVTVAIALVSLFTVPWLGRVGQVTPPKQTISSTVESESVPECATGQTRCATTSRSTVSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q252</accession>
    <name>D3Q252_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017490.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2229"/>
    <dbReference type="EnsemblBacteria" id="ADD41919">
        <property type="protein sequence ID" value="ADD41919"/>
        <property type="gene ID" value="Snas_2229"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2229"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066229_0_0_11"/>
    <dbReference type="OMA" id="THYLAWN"/>
    <dbReference type="OrthoDB" id="1751860at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049466" evidence="2">
        <location>
            <begin position="40"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="311" mass="33498" checksum="22EE7862B98D39BB" modified="2010-04-20" version="1">MIWVAWRQHRAGVLTALAVLATAATVMLVMRLSIDAAFAKAKAPDCLTNPGSCTEDAFNAVMNSYGMYVTMAPTVLYLFPVLLGIVAGAPVFARELSLGTHMFSLTQSVSRKRWWAVKLGVTLLPIAVGTCLLGLLSAWAIGPLVNMLGGRIQPGFFEVQGLVMAGYMVFAFAVASTFGLLTRNNVVPMVVTAGVFIAVAVTVAVFARPSYLPAEQATVTNPKGQDEFAVQTPEHSWRVGEIFVDKDDNTYTSYAEVCNPESCVEDDVVSYTVEYHPDSRFWTFQGIETGAYLVLGAAALAVGARRLRALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q287</accession>
    <name>D3Q287_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold-shock DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_4169</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019391.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4169"/>
    <dbReference type="EnsemblBacteria" id="ADD43820">
        <property type="protein sequence ID" value="ADD43820"/>
        <property type="gene ID" value="Snas_4169"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4169"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117621_0_3_11"/>
    <dbReference type="OMA" id="FEIQDGH"/>
    <dbReference type="OrthoDB" id="2034748at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="67" mass="7517" checksum="71FB9ACC453D29F6" modified="2010-04-20" version="1">MANGTVKWFNAEKGFGFIERDGNEPDVFVHFSAIQTQGYRELSEGQKVEFEVTQGQKGPQAENVKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2B3</accession>
    <name>D3Q2B3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019417.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4196"/>
    <dbReference type="EnsemblBacteria" id="ADD43846">
        <property type="protein sequence ID" value="ADD43846"/>
        <property type="gene ID" value="Snas_4196"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4196"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066439_1_0_11"/>
    <dbReference type="OMA" id="YLVDHPA"/>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="42"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="279" mass="30051" checksum="A3676BFC7B1FDA01" modified="2010-04-20" version="1">MSNDGFVWSAEASDLAKAAQSDGEFYRLMAAELLRPDDRLAVDFGCGGGGMALALRDRAAETGQATRVVGLDAHEEVFTTVAADNPDLGFAVASFEDSPEQLRAAAGGAPDLVWARGALHHADDEQVALRTLAEVLADGGVIALAEGGTTAACLPNYLGIGKPGLDKRLNAAADEAARRRMADLKPMPYGWLTGLRNAGFIDVTTRNILFDKPAPLEGADLDHVLRKFAKQIEWSEDLLSPEDLECWRRLLDPDDPVWLGLRDDLFYLAAQSVHIGRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2H9</accession>
    <name>D3Q2H9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019483.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4263"/>
    <dbReference type="EnsemblBacteria" id="ADD43912">
        <property type="protein sequence ID" value="ADD43912"/>
        <property type="gene ID" value="Snas_4263"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4263"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_11"/>
    <dbReference type="OMA" id="CGLANIN"/>
    <dbReference type="OrthoDB" id="1821409at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="247" mass="25665" checksum="50171FECAA2E36AE" modified="2010-04-20" version="1">MPQLEGKGAVVTGGSRGIGRAIVERLAADGATVVFSYASNKTAADEVVATVTASGGTAHAVAADFTDPEAPERLMAAAAELLPGLDILVNNAVMEITPTPLTEVTDELFDTTFTANARAPFQTLRYAAKNMNDDGRVINISTLNTSRPFPGLTTYVSGKGALEQMTNVAAFELGARGITANVVSPGATDTDLLRDTNPPEALEMLNTMTPLGRLGLPSDIADVVSFLAGPDSRWITGQNIRATGGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2M1</accession>
    <name>D3Q2M1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_6149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013021343.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6149"/>
    <dbReference type="EnsemblBacteria" id="ADD45772">
        <property type="protein sequence ID" value="ADD45772"/>
        <property type="gene ID" value="Snas_6149"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6149"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_7_0_11"/>
    <dbReference type="OMA" id="YIAYNVM"/>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048182" evidence="1">
        <location>
            <begin position="29"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="83"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="566" mass="62457" checksum="E9FAE058DD1945FA" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2P8</accession>
    <name>D3Q2P8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6176"/>
    <dbReference type="EnsemblBacteria" id="ADD45799">
        <property type="protein sequence ID" value="ADD45799"/>
        <property type="gene ID" value="Snas_6176"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6176"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080407_0_0_11"/>
    <dbReference type="OMA" id="TGYRVYD"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="129"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="244" mass="26767" checksum="0165250B1F379CB4" modified="2010-04-20" version="1">MRPTDLAAEHGISTQAVRNYERDGYLPSAERTASGYRIYTEAHAAALRAYLALIPAYGHEAAGQIMTDVHDDDVDHALLVIDRGHQQLLRDRETLAAVENAIGNLMDDAEARTAADGHTVPGPSPESLPWTIGDLAHRLRVTPATLRNWEEAGILVPERNRATGYRVYGSKDIRDAELAHLLRRGGYPLEHIATVVEQIRTVGGTGTLAASLADWRRRLTARGLAMLHSATKLSDYLERRAPIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2V8</accession>
    <name>D3Q2V8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_6238</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6238"/>
    <dbReference type="EnsemblBacteria" id="ADD45859">
        <property type="protein sequence ID" value="ADD45859"/>
        <property type="gene ID" value="Snas_6238"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6238"/>
    <dbReference type="eggNOG" id="ENOG5032XQ0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_798412_0_0_11"/>
    <dbReference type="OrthoDB" id="906153at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="357" mass="39966" checksum="CC151AC6BC5D6C87" modified="2010-04-20" version="1">MTDTQFPRFSATDVPRLRRELAEWYGSPKGPDFYYQAIKMGRQAIKPPGSPEKAAVQLAATETKRLSEGDLWYVDDDLCALLNAAHPTMPKFAPQPWDLPGKVGFAVFAEPLYRPLSDDQTLTSDLEARAAADPDFAPIADRLLQDDSGILAVSWGPVSNPYWPAGGLWMSFYSEALAHQDAAFFEDPRQAAWARNQLPVLIVDNEATMAWQHDAAPVEEFQLPGPDEPVTTLSWARLVFAAFQLASQGNLSETDTVAPGRPERRRTDRAGLPAKDVRVVRLRRSVTDSRADDGAETSRQYRHRWVVRGHWRNHWYPARKTHRPTWIAPYLKGPETAPLLGGERVTVIDAPKQADES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Y4</accession>
    <name>D3Q2Y4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015525.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0235"/>
    <dbReference type="EnsemblBacteria" id="ADD39954">
        <property type="protein sequence ID" value="ADD39954"/>
        <property type="gene ID" value="Snas_0235"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0235"/>
    <dbReference type="eggNOG" id="COG4805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018914_3_0_11"/>
    <dbReference type="OMA" id="GRMWWAV"/>
    <dbReference type="OrthoDB" id="520320at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="560" mass="62358" checksum="5C73114E4C8A8AA2" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q2Z8</accession>
    <name>D3Q2Z8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0250</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015539.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0250"/>
    <dbReference type="EnsemblBacteria" id="ADD39968">
        <property type="protein sequence ID" value="ADD39968"/>
        <property type="gene ID" value="Snas_0250"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0250"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_5_1_11"/>
    <dbReference type="OMA" id="QRISRRW"/>
    <dbReference type="OrthoDB" id="1677723at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010211">
        <property type="entry name" value="Redox-sen_tscrpt-act_SoxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015358">
        <property type="entry name" value="Tscrpt_reg_MerR_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30204:SF0">
        <property type="entry name" value="PTHR30204:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09278">
        <property type="entry name" value="MerR-DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01950">
        <property type="entry name" value="SoxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH merR-type" evidence="7">
        <location>
            <begin position="8"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD39968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="154" mass="17527" checksum="745FA146050C269C" modified="2010-04-20" version="1">MNTGPDNHLTMGEVIRRTGVAASALRFYEHKGLIFSERDRGNHRIYARHMLRRVSLIIVAKRLGIPLADIAEVFATLPRDHEPSHDDWQRVSRGWRKRLARRRRAIENLERELTGCIGCGCLSMKACLLLNPDDTLEPQGPGPVRLRETETALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q329</accession>
    <name>D3Q329_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator, BadM/Rrf2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD39999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015570.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0281"/>
    <dbReference type="EnsemblBacteria" id="ADD39999">
        <property type="protein sequence ID" value="ADD39999"/>
        <property type="gene ID" value="Snas_0281"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0281"/>
    <dbReference type="eggNOG" id="COG1959">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107144_1_0_11"/>
    <dbReference type="OMA" id="RCAEIRQ"/>
    <dbReference type="OrthoDB" id="1794390at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030489">
        <property type="entry name" value="TR_Rrf2-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01332">
        <property type="entry name" value="HTH_RRF2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD39999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="158" mass="16588" checksum="AF515FCD11EB2EC6" modified="2010-04-20" version="1">MKMTSGVEWALHACVTLSQAADPVPAARLAELHGTPPAYLAKQLQSLARAGIVTSTAGQVGGYTLTRPATEVTVLEVVQAVDGTEPAYRCTEIRQRGPLAVPAEKCERSCAIARAMAEAQEAWSRALSRITIADLARGIDADSDGTAMADVRGWLAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3K1</accession>
    <name>D3Q3K1_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_2356</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BioY family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017613.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2356"/>
    <dbReference type="EnsemblBacteria" id="ADD42042">
        <property type="protein sequence ID" value="ADD42042"/>
        <property type="gene ID" value="Snas_2356"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2356"/>
    <dbReference type="eggNOG" id="COG1268">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077931_2_0_11"/>
    <dbReference type="OMA" id="FWPVPMT"/>
    <dbReference type="OrthoDB" id="1691691at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015225">
        <property type="term" value="F:biotin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003784">
        <property type="entry name" value="BioY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34295">
        <property type="entry name" value="PTHR34295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02632">
        <property type="entry name" value="BioY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016661">
        <property type="entry name" value="BioY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR016661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD42042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="200" mass="20073" checksum="95BF989FFA55B814" modified="2010-04-20" version="1">MSSHAATVAPRMVLADLIPTTKVNAWARDLVLVASGAALTGASAQIAFTIPAITPVPFVLTTLTVLLVGAALGPVRAAAAMGLYLAAGVAGLPWFAEGTSGLGASFGYIIGYLAAGALVGALAKRGGDRTLVRTAGLMVLGNLAIYAFGVPYLILATGMSVSDGLLKGAVPFLVGDLIKLVAAAALLPATWALVAKFRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3T0</accession>
    <name>D3Q3T0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_4350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4350"/>
    <dbReference type="EnsemblBacteria" id="ADD43997">
        <property type="protein sequence ID" value="ADD43997"/>
        <property type="gene ID" value="Snas_4350"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4350"/>
    <dbReference type="eggNOG" id="ENOG50326KH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2847700_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="65" mass="7565" checksum="C2B594A02B5080D8" modified="2010-04-20" version="1">MAMTLRLPQADDQMLTERAAHEGRSKHELVVEAVHTMLTERNEFFDRMLNHGIADNCELLDRLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q3T5</accession>
    <name>D3Q3T5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acetolactate synthase small subunit</fullName>
            <shortName evidence="8">AHAS</shortName>
            <shortName evidence="8">ALS</shortName>
            <ecNumber evidence="8">2.2.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetohydroxy-acid synthase small subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_4355</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 8">Dimer of large and small chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the acetolactate synthase small subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019573.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4355"/>
    <dbReference type="EnsemblBacteria" id="ADD44002">
        <property type="protein sequence ID" value="ADD44002"/>
        <property type="gene ID" value="Snas_4355"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4355"/>
    <dbReference type="eggNOG" id="COG0440">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055003_1_3_11"/>
    <dbReference type="OMA" id="EPYGIKE"/>
    <dbReference type="OrthoDB" id="1500398at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990610">
        <property type="term" value="F:acetolactate synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04878">
        <property type="entry name" value="ACT_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004789">
        <property type="entry name" value="Acetalactate_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019455">
        <property type="entry name" value="Acetolactate_synth_ssu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039557">
        <property type="entry name" value="AHAS_ACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30239">
        <property type="entry name" value="PTHR30239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10369">
        <property type="entry name" value="ALS_ss_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00119">
        <property type="entry name" value="acolac_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="5"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD44002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="172" mass="18572" checksum="BAF303A6483B8696" modified="2010-04-20" version="1">MRTRTLSVLVENKPGVLSRVTALFSRRNFNIDSLAVGETEHPGVSRITIVVDESDHPLEQVTKQLNKLINVLKIVELESESSVQRQLLLVKVRADAVSRSQVVEAAGLFRAKVVDVTPETVTIEATGSAGKIEALLQVIEPFGIAELAQSGLVGLGRGAKSMTSMARSRSNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q422</accession>
    <name>D3Q422_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_6287</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6287"/>
    <dbReference type="EnsemblBacteria" id="ADD45907">
        <property type="protein sequence ID" value="ADD45907"/>
        <property type="gene ID" value="Snas_6287"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6287"/>
    <dbReference type="eggNOG" id="COG1121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_11"/>
    <dbReference type="OMA" id="VSHDIDM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD45907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="264" mass="28283" checksum="756BE4545AD83091" modified="2010-04-20" version="1">MKQVTPAMEGVAVSARYGARTVLSGLDFVIPKGQMTVLLGPNGSGKTTLLHVLAATHPVAEGRLLRHHQRRPALVPQHSQVSDSFPITVRQTVAMGRWADRGPWRPTTRADKAVVAEALDQLGIADLAGRRLGMLSGGQRQRVLLAQALAQRSDVVLLDEPTAGLDVTSAERIHTHLARLRSRGVTIVQSTHEPEAAATADHRIHLGAPVSVGGQDFGPLSATHPRITGHCGVPTARRMGRPGSGLGCRSDQDRHCFSLWQAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q445</accession>
    <name>D3Q445_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase FkbM family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_6312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_6312"/>
    <dbReference type="EnsemblBacteria" id="ADD45930">
        <property type="protein sequence ID" value="ADD45930"/>
        <property type="gene ID" value="Snas_6312"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6312"/>
    <dbReference type="eggNOG" id="COG0220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_874087_0_0_11"/>
    <dbReference type="OMA" id="MDTQGHD"/>
    <dbReference type="OrthoDB" id="1340956at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_21" evidence="1">
        <location>
            <begin position="117"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD45930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="318" mass="34753" checksum="6BFCF8A42BEBFE4B" modified="2010-04-20" version="1">MFNALSTIGFKVYDLGPGTGLVTRRKDYQVVDVSSRSWLVTRGKQDPVVAKAVALANGDKVASGQKSVLLGPNAKLVLDDNAVVGDEHGFQKPAHNYLCNRHVAELLRHYRVNCVFDVGANVGQYAKNLRKFGYTGRIVSFEPVPHIAEKLRAAAEGDPDWQVHQCALGREAGSVTMNVVKGSMSSILGPTDFGSTRYKRFNNIDKVDVPVHRLDAIMDEAMAGLDDPRPYLKLDTQGLDLEAFAGTGDRVKQLVGMQSEVALMHIYEGMPGMMEALGVYTEAGFEITGMYPVSREQTTKRVLEFDCVMARAESAPAV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-11-02" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4A8</accession>
    <name>MSHD_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mycothiol acetyltransferase</fullName>
            <shortName evidence="1">MSH acetyltransferase</shortName>
            <ecNumber evidence="1">2.3.1.189</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Mycothiol synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mshD</name>
        <name type="ordered locus">Snas_6377</name>
    </gene>
    <organism>
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = CoA + H(+) + mycothiol</text>
            <dbReference type="Rhea" id="RHEA:26172"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16768"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
            <dbReference type="EC" id="2.3.1.189"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyltransferase family. MshD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.189" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D3Q4A8"/>
    <dbReference type="SMR" id="D3Q4A8"/>
    <dbReference type="STRING" id="446470.Snas_6377"/>
    <dbReference type="PRIDE" id="D3Q4A8"/>
    <dbReference type="EnsemblBacteria" id="ADD45993">
        <property type="protein sequence ID" value="ADD45993"/>
        <property type="gene ID" value="Snas_6377"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_6377"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068014_0_0_11"/>
    <dbReference type="OMA" id="AEPWFDP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035447">
        <property type="term" value="F:mycothiol synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010125">
        <property type="term" value="P:mycothiol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01698">
        <property type="entry name" value="MshD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017813">
        <property type="entry name" value="Mycothiol_AcTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021524">
        <property type="entry name" value="MSH_acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03448">
        <property type="entry name" value="mycothiol_MshD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0012">Acyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000400300" description="Mycothiol acetyltransferase">
        <location>
            <begin position="1"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase 1" evidence="1">
        <location>
            <begin position="5"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase 2" evidence="1">
        <location>
            <begin position="159"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside</name>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
        </ligand>
    </feature>
    <feature type="binding site">
        <location>
            <begin position="82"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside</name>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside</name>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside</name>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="242"/>
            <end position="244"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside</name>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="281"/>
            <end position="286"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01698"/>
        </source>
    </evidence>
    <sequence length="306" mass="33514" checksum="B142E4FE562EF7EE" modified="2010-04-20" version="1">MIRVEIYERLEAAAVAEVLELVEAGARADGLSALNEQTILNLRHGGAEAEPGAHLMIRDAEGTLVGYANLELDNDGVAAVEMLVHPTHRHNGHGEALLAALIKRATAAKCRALTIWAHGDHPTALLLADRHDFTRDRVLWQMRRHLTDADGDGEPAAGITIRSFVPGRDETRLLEVNNAAFADHPDQGGWTVRDIAMREREDWFDPEGLLLAERDVDGQVLGFHWTKVHGSGDSAIGEIYVLGVAPEAQGLKLGAALTTAGLRYLRGRGLDTVMLYVDESNVRAVRLYTGAGFTRWTTDVNYHKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4H6</accession>
    <name>D3Q4H6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_0419</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015707.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0419"/>
    <dbReference type="EnsemblBacteria" id="ADD40136">
        <property type="protein sequence ID" value="ADD40136"/>
        <property type="gene ID" value="Snas_0419"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0419"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_11"/>
    <dbReference type="OMA" id="RMDANFR"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="34"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="261"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD40136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="574" mass="60634" checksum="1C44B1F5B78002C5" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4S5</accession>
    <name>D3Q4S5_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Transketolase</fullName>
            <ecNumber evidence="3 8">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Snas_2422</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the transketolase family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="3 8"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2422"/>
    <dbReference type="EnsemblBacteria" id="ADD42105">
        <property type="protein sequence ID" value="ADD42105"/>
        <property type="gene ID" value="Snas_2422"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2422"/>
    <dbReference type="eggNOG" id="COG0021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009227_0_0_11"/>
    <dbReference type="OMA" id="HHTEGIE"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="PTHR43522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="9">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ADD42105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="695" mass="75497" checksum="0CEBE6E5E292B6FC" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q4S7</accession>
    <name>D3Q4S7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017678.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2424"/>
    <dbReference type="EnsemblBacteria" id="ADD42107">
        <property type="protein sequence ID" value="ADD42107"/>
        <property type="gene ID" value="Snas_2424"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2424"/>
    <dbReference type="eggNOG" id="COG0189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070819_0_1_11"/>
    <dbReference type="OMA" id="STWDYSW"/>
    <dbReference type="OrthoDB" id="878336at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="286" mass="30969" checksum="571E85925AB48312" modified="2010-04-20" version="1">MPTVAIVTCAELPDLDSDETLLLEPLRARGVDPVAAVWNDPAVDWDSFDATVVRCSWDYSRQRGRFLSWARTVPRLHNRAGLLEWNTDKRYLGDLAGAGVPVVPTTWLPPGTHVELPDAGEWVLKPSIGAGSRDAGRYLMGDVAQRERACELVSRLHAGGATVMAQPYMDDVDVNGERALVYLDGVFSHAVRKGAMLDGPYEGDVELFKAETIAPATATEAELALGKIVMDTIEGEPPLYARVDVVGTDANLLLLELELTEPSLFYTHSEGAAERMADAIAAKLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q515</accession>
    <name>D3Q515_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Snas_4418</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4418"/>
    <dbReference type="EnsemblBacteria" id="ADD44064">
        <property type="protein sequence ID" value="ADD44064"/>
        <property type="gene ID" value="Snas_4418"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4418"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1224133_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="47"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="164"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ADD44064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="226" mass="24434" checksum="5FDAC6C8F2A108F6" modified="2010-04-20" version="1">MDTQQPGRSLPKAPRPSRSTASPASANSLRSWAKAAATGDTEAFVRLYASCRGWVLGRCRAQLAVHDAEDACAEVFTRAWRHLHSGKTIEHPLAWLATVTRHLIIDYRKRAARTPPSGDLACDFLPDMTPRDADTVHAGRCDPSPGPADLASVIDVTPVVRSWLAALPSQASAVVTGYLANEDPAATSNRLGCSVAAVRSSLYRARKHLRTRLAAHDLPCPPIRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q600</accession>
    <name>D3Q600_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0585"/>
    <dbReference type="EnsemblBacteria" id="ADD40299">
        <property type="protein sequence ID" value="ADD40299"/>
        <property type="gene ID" value="Snas_0585"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0585"/>
    <dbReference type="HOGENOM" id="CLU_657059_0_0_11"/>
    <dbReference type="OMA" id="PHNEPRV"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="418" mass="42792" checksum="190AB785595EC1CA" modified="2010-04-20" version="1">MAAGETRAAYPRRSTARRAVAEAAAPTAPAAAAHPAADHRAGSTAERRAVAVAAVAPTAGYPEPAAVEAGAAGPTGPDRPRTAHRKPVLPEVAVAAPTEPVHPKKARPKPVPREEAAAPTGMAPRKRALPGAAADPTEPVHPKKAPQRPAPQAEAAAPTAVHRRAARTSAVRAEAADRQPVPTVARPLADRKPVARTSAVTAAGEDPRPDPTAAADPRRARRKPAGHPTAARSRADPRPDRAGPTAVHPEAEAGRRRAAPTAGSAAAAATASHHPRAVAVAAEPHRASTRYWCAAPHREAACSSTAATVATAAAATARAGREPAAQAASRRAAAAGPTAADTGHRPAGARTAAARLRAEPGAHHTAGTVACQVRRACHRPRNCCCPFAWLPAQVFRFTGARRPRDGRSTHRRMNSAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q605</accession>
    <name>D3Q605_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_0590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015875.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0590"/>
    <dbReference type="EnsemblBacteria" id="ADD40304">
        <property type="protein sequence ID" value="ADD40304"/>
        <property type="gene ID" value="Snas_0590"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0590"/>
    <dbReference type="eggNOG" id="COG1126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="EFIYIIG"/>
    <dbReference type="OrthoDB" id="1191583at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="11"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD40304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="257" mass="28099" checksum="F2F7A1E67E0A2364" modified="2010-04-20" version="1">MSEQSTVDPQVQIRGLHKSFGKLKVLKGIDISIRSGEVVCVIGPSGSGKSTLLRCVNLLEQPTAGEIVVDGYLLTDRDADLNLARRHIGMVFQQFNLFPHLNVLDNVAVAQRKVLKTPKATARKVAMEQLEKVGVAEKAKEFPARLSGGQQQRVAIARALSMEPDLMLFDEPTSALDPELVGDVLTVMRELAADGMTMMVVTHEMGFARDVADRVVFMDGGVIVEEGQPADVLENPSAERTREFLKRVLDPTHADEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6A7</accession>
    <name>D3Q6A7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_2603</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017853.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2603"/>
    <dbReference type="EnsemblBacteria" id="ADD42282">
        <property type="protein sequence ID" value="ADD42282"/>
        <property type="gene ID" value="Snas_2603"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2603"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_0_6_11"/>
    <dbReference type="OMA" id="RALHHWD"/>
    <dbReference type="OrthoDB" id="1467120at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036244">
        <property type="entry name" value="TipA-like_antibiotic-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012925">
        <property type="entry name" value="TipAS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07739">
        <property type="entry name" value="TipAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89082">
        <property type="entry name" value="SSF89082"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0010">Activator</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH merR-type" evidence="5">
        <location>
            <begin position="16"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD42282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="274" mass="30674" checksum="41BEEF9EAF899DB7" modified="2010-04-20" version="1">MTGDDTRGGPPADTDGLTVGRTANLVGVSIRTLHHWDSIGLVSPSDRTWAGYRVYSNEDIARIHRVLVYRELGFELAQIGRILDDRGVDATEHLRRQRGQLVEQIDRLRSMVGSVDRMLAAAREGMRLTPEQQVEIFGTDWRPEWVDEARQRWGDTTQWAQYSERAAALSTAEWEQVASETRAFEADLSDAKRSGVEPGTAAANALAERHRALMSTYFDCTHAMQVCMGRMFVEDPGFAEHYDKLAPGLAVWLREVLFANARANGVDPATAVWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6C2</accession>
    <name>D3Q6C2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_2619</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2619"/>
    <dbReference type="EnsemblBacteria" id="ADD42297">
        <property type="protein sequence ID" value="ADD42297"/>
        <property type="gene ID" value="Snas_2619"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2619"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_44_1_11"/>
    <dbReference type="OMA" id="RAPKGDM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="4">
        <location>
            <begin position="22"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="221" mass="24160" checksum="60990293CE16571F" modified="2010-04-20" version="1">MPHAHTSPTSDDNKSLRQRRTAKRREDILRAATEIFGNRGYKSGSLTEIAEQVGMTHAGILHHFGSKNQLLLAVLDYRDEADVQDLEGKHPPEGMDLFKHLVDTARLNSTRPGIVQTYAVLSADSVTDNHPAQDYFRDRFTELRAMIARSLSQICEPDAMPSSAALDTAASAIIGVMDGLQVQWLLDDINVDLPHATAFAIDAILAALVAGRTGSRLESDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6F7</accession>
    <name>D3Q6F7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein serine/threonine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019771.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4556"/>
    <dbReference type="EnsemblBacteria" id="ADD44200">
        <property type="protein sequence ID" value="ADD44200"/>
        <property type="gene ID" value="Snas_4556"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4556"/>
    <dbReference type="eggNOG" id="COG0631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034545_2_1_11"/>
    <dbReference type="OMA" id="KVCVACR"/>
    <dbReference type="OrthoDB" id="1835483at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="81"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="339" mass="34904" checksum="A90286BC4773A581" modified="2010-04-20" version="1">MNSSPTCPVCDAPAAPDHLVCEACGSDLDQSGSPGHWMSSASQTSACADCGSSDLDAKGYCGNCGRRQNPTADRTQLDLTRIGAATDFGKRHHYNQDALAIGRYDGTSVAVVCDGVSSSTFGELAALAASEAAVAEILNSLADKHTPAEASHAGVVAGAAAAARAGSGLEDNPPSCTYVSAVVNDSEIEVTWVGDSRAYWVSGDYAECLTVDDSYVGRLRAIDAPADDPRYHTPYAHALLAWLGADSPELKPNTHTYIPDGPGLLIVCSDGLSCYMNEPADLLPLPAGDPVDMATALTERARDQGGKDNISVAIAKFPAGGEVAMPGDATVRLARGSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6P9</accession>
    <name>D3Q6P9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_4649</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019863.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4649"/>
    <dbReference type="EnsemblBacteria" id="ADD44292">
        <property type="protein sequence ID" value="ADD44292"/>
        <property type="gene ID" value="Snas_4649"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4649"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_0_11"/>
    <dbReference type="OMA" id="LTMTNGQ"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="100"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD44292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="325" mass="35742" checksum="5DF89D71A860E5C7" modified="2010-04-20" version="1">MTFDFLDQLPKFGVLGVGLLAFLAVVFAVLYIGNVVPDKPKSLTTGLVFLIPTLLLVGIGLVVPAIRTTILSFTDKTGEAAVGWKNYEWIFTSPDILQVVGNSALWVVFTPLLATAVGLVYAILIDRSRFESLAKTLVFLPMAISFVGASIIWKFMYTEREIGDQIGLLNQIVVWLGGSPTDFLAIPFWNNFFLIIVMVWIQAGFATVVLSAAIKGIPAEIVEAARLDGVNAWQMFWRVTVPSIRPAIIVVIVTMSIASLKLFDIVRTMTGGNDGTSVLAYEMYSQSFPSQQTGRGAALAVVLFILVVPIIMYQVRNMRQRREVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6S6</accession>
    <name>D3Q6S6_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015896.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0611"/>
    <dbReference type="EnsemblBacteria" id="ADD40325">
        <property type="protein sequence ID" value="ADD40325"/>
        <property type="gene ID" value="Snas_0611"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0611"/>
    <dbReference type="eggNOG" id="ENOG5030VFP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1342585_0_0_11"/>
    <dbReference type="OrthoDB" id="248593at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="215" mass="24087" checksum="1DE3DD7703B37247" modified="2010-04-20" version="1">MSFRRFNPRRDALPALHDGWLRSGERPIWADGFNSIRYAVEGRKRGTVPKRHPVLRVARWALYPYTLSKGWAAGPMYKSVPAGPSSAPEEPVAFGSHPDCEASQLAGTDVNEYRAFWVLTDHRFAGVTVESVPTDPASRTSSILGRGAQIVRELGQIFTGTINNLPPEPVRLRTLWELRPGQYSREGPVKRGLYDYHRVTFADGSGIDFPSRPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6S8</accession>
    <name>D3Q6S8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0613</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013015898.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0613"/>
    <dbReference type="EnsemblBacteria" id="ADD40327">
        <property type="protein sequence ID" value="ADD40327"/>
        <property type="gene ID" value="Snas_0613"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0613"/>
    <dbReference type="eggNOG" id="ENOG5030VFP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1342585_0_0_11"/>
    <dbReference type="OrthoDB" id="248593at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="204" mass="23119" checksum="280BCF8C66487ABA" modified="2010-04-20" version="1">MSYRRFNPERDTAPALSHGWLQPGERLAWPTPEFGAVNYKVHRRTGEGVPIRHPFWRALGVALISPFLLVDNIRNFLYGILDGPEAPQPIAFGKRWDCLAARLADADDYHSIWVLTDRRFASVSADPLSGTSDTTMARLGDFAKDVGQTFTGGIHTLPVESVRIRTVWQLGTDQYRYDGVVKRWRTEYDRITFPDGSGIDFPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q6U9</accession>
    <name>D3Q6U9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_0634</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0634"/>
    <dbReference type="EnsemblBacteria" id="ADD40348">
        <property type="protein sequence ID" value="ADD40348"/>
        <property type="gene ID" value="Snas_0634"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0634"/>
    <dbReference type="HOGENOM" id="CLU_2620330_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD40348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="78" mass="8403" checksum="9BB4DFE60F21BE30" modified="2010-04-20" version="1">MAFTAADEARARTIAGYAAQRLADFLPGFDKNMIAISREADPGLMLPLYCDQDIYCLLAPEHAGPCRDINGTNLDGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q722</accession>
    <name>D3Q722_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0708</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the MIP18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0708"/>
    <dbReference type="EnsemblBacteria" id="ADD40421">
        <property type="protein sequence ID" value="ADD40421"/>
        <property type="gene ID" value="Snas_0708"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0708"/>
    <dbReference type="eggNOG" id="COG0489">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2151">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024839_0_0_11"/>
    <dbReference type="OMA" id="NMAYFTP"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="6">
        <location>
            <begin position="12"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="128"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="384" mass="39696" checksum="D67D08ABD5AC418E" modified="2010-04-20" version="1">MGTMSAPATTVEQAIHTALATVQDPEIRKPITELGMVESVTVDGSHAALRILLTIAGCPLKDKLRSDITAATTSVAGIESVSIDFGAMTDAQRKDLQTKLRGDSGGGDPVIPFSQPGSRTRVFAVASGKGGVGKSSVTVNLAAALSSRGLSVGVVDADIYGHSVPRMLGAADARPTPVESMIMPPQANGVKLISIGMFTKGNAAVVWRGPMLHRALQQFLADVYWGELDVLLLDLPPGTGDIAISVAQLLPGAELLVVTTPQAAAAEVAERAGAIAMQTHQRLTGVVENMSWLETPDGSRMEIFGSGGGEAVSEALTKRMGADVPLLGQVPLEPQLREAGDAGVPLVLSQPDSAAAKALFGIADRLAVRRESLAGKPLGLAPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q795</accession>
    <name>D3Q795_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aspartyl/Asparaginyl beta-hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_2689</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017937.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_2689"/>
    <dbReference type="EnsemblBacteria" id="ADD42366">
        <property type="protein sequence ID" value="ADD42366"/>
        <property type="gene ID" value="Snas_2689"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2689"/>
    <dbReference type="eggNOG" id="COG3555">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_865759_0_0_11"/>
    <dbReference type="OMA" id="CWTEERT"/>
    <dbReference type="OrthoDB" id="1564693at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018193">
        <property type="term" value="P:peptidyl-amino acid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007803">
        <property type="entry name" value="Asp/Arg/Pro-Hydrxlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05118">
        <property type="entry name" value="Asp_Arg_Hydrox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asp_Arg_Hydrox" evidence="2">
        <location>
            <begin position="26"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD42366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="321" mass="35618" checksum="A28E90AFC1877E50" modified="2010-04-20" version="1">MTTPSLEQRWESVPATAALDRVYDASLLAAEVNALREQTWKVQRSVGQDGVYGGAAIDWTILSLRSAGGDPARTDPGGAGPVDHADTPHLDRSPELAKVLRDIPTTLLAVRLMALGPGVEVKEHRDAKCGLPWGMTRLHIPVITNPGSFVVIEGRDYHWDAGRLWFGDFNRLHYVRNDGEEARIHLVLDCLVSPELLDLFPSEFRDALPERDVLVTRPNLPSPPVTRCRFRMPARFVEWSEEEPVAAIDELVDAEVVPGDDGPVLHVDGKPTFGLVHVGDDEFRFTGWSEERTVKLANGHVRCRTRLGERMSETVCLTELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7A9</accession>
    <name>D3Q7A9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2704</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013017951.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42380">
        <property type="protein sequence ID" value="ADD42380"/>
        <property type="gene ID" value="Snas_2704"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2704"/>
    <dbReference type="HOGENOM" id="CLU_2773908_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="69" mass="7690" checksum="965212493D92FBEE" modified="2010-04-20" version="1">MHWEDGEGKGRVIYGDLSDGYVTFKRVEGGDGRYTFESVADDDGGALVNANYAKRIQLFDETITLKDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7R3</accession>
    <name>D3Q7R3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019976.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4763"/>
    <dbReference type="EnsemblBacteria" id="ADD44405">
        <property type="protein sequence ID" value="ADD44405"/>
        <property type="gene ID" value="Snas_4763"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4763"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_0_1_11"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="23"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="252" mass="27903" checksum="30F64E731EFE02F7" modified="2010-04-20" version="1">MEPTPAAIRAAQRGTTKRTPRVELSLDRIVTAAIHLADRDGLPGISMAKVAKELGFATMSLYRHLDSKEELLLHAQDSAIGPPPANIATAPDWRTCLTRWTRELVTAYRRHPWAAEIPVTGPPLLPRSLEWLNAGLTTLRTLPLQPLEKLSTMSLLGGYARTEVTLRAIIDKEAALDPNARPDLEYESQLRTLTAHRDLPALTEMLATGDIFTLPSDTPTDDGDDFMVDFGLERILDGIQALITRREGSRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7R9</accession>
    <name>D3Q7R9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_4769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019982.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4769"/>
    <dbReference type="EnsemblBacteria" id="ADD44411">
        <property type="protein sequence ID" value="ADD44411"/>
        <property type="gene ID" value="Snas_4769"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4769"/>
    <dbReference type="eggNOG" id="COG1765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100275_4_0_11"/>
    <dbReference type="OMA" id="CPIHKLM"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="153" mass="16656" checksum="B01FEAA17404F656" modified="2010-04-20" version="1">MTNSGEPNEGLVTVTGTGPGSFVQRIRAGAHELTADEPQPTGTDTGASPYDLLLAALGSCTSMTLQMYADRKKWPLEKVSVSLRHDRIHATDCANCETEAGMVSQITRVIRLEGPLDEEQRTRLLQIADRCPVHRTLSGEIDIQTEMDAAKPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7T4</accession>
    <name>D3Q7T4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_4785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019997.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4785"/>
    <dbReference type="EnsemblBacteria" id="ADD44426">
        <property type="protein sequence ID" value="ADD44426"/>
        <property type="gene ID" value="Snas_4785"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4785"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083329_0_0_11"/>
    <dbReference type="OMA" id="MIGQPMD"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="39"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="289" mass="30736" checksum="54259617F0E5F1DD" modified="2010-04-20" version="1">MTDPKSHELEVPNAVVTYDVREPAAPSDKPTLLMFASPMEAAAFATLAGHFTDRTVVTYDPRGAGRSKRTDGTSLSTPDEHADDLHRIITELGTGPVDVFASSGGAVNALALVAKHSDQVRTVVAHEPPASQEVPDRENALAACVDIRRTYEASGFGPAMAKFIALVMHKGELPDDYTDQPGPDPAAFGLPTEDDGSRDDPLMGNIVNSNHYKHDFDALRAASTRVVLAVGVESEGELPARAATAVAERLGIEPTMFPSHHAGFTGEESGMAGEPEAFAVRLREVLDQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q7X8</accession>
    <name>D3Q7X8_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_0771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016054.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0771"/>
    <dbReference type="EnsemblBacteria" id="ADD40483">
        <property type="protein sequence ID" value="ADD40483"/>
        <property type="gene ID" value="Snas_0771"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0771"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125060_0_0_11"/>
    <dbReference type="OMA" id="RFTWELG"/>
    <dbReference type="OrthoDB" id="1907687at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="120" mass="12937" checksum="1B8B94C8A1B26F71" modified="2010-04-20" version="1">MYDFHAIAAKYLDAFNATDTDRRAELLAEVFTKDVSYVDPMAAVTGHEGLDAFITGAHGQFPGWTFSLVGAVDGHNNQARFSWGLGPEGEEPPVLGFDVVVLDADGRVKSVHGFLDRVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8H2</accession>
    <name>D3Q8H2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_2871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018117.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42546">
        <property type="protein sequence ID" value="ADD42546"/>
        <property type="gene ID" value="Snas_2871"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2871"/>
    <dbReference type="eggNOG" id="ENOG50313ED">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2738090_0_0_11"/>
    <dbReference type="OrthoDB" id="2092783at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD42546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="71" mass="7583" checksum="C84BCCA1EA3B85A7" modified="2010-04-20" version="1">MTNHEETSPNRCPICELGMSAALTVVSRHRTSTGTVVYARCQCGRLSMWSEAAATVTAPPELRTLASCKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q8S0</accession>
    <name>D3Q8S0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_4871</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020083.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_4871"/>
    <dbReference type="EnsemblBacteria" id="ADD44512">
        <property type="protein sequence ID" value="ADD44512"/>
        <property type="gene ID" value="Snas_4871"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_4871"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="IARIYQK"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="12"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="222" mass="23457" checksum="74BF890893D91B94" modified="2010-04-20" version="1">MNSPNTNEDVTTVLIVDDHDLIRKGLRHAFSRDPQFEVVAEAGSAGDGLRKAAALQPNVVIMDLRLPDGSGLEATRKLRKAHPSMGIVVLTMYAGDDQLFGALEAGASAFVPKSAPSDDVVSAARHAATTPNAFTAADLAEAMKRRLTPSGPQLSPRESQVLKLLADGMSVAGIAKQLYVSESTAKTHISKLYEKLGAGNRAQALMTALKLGLLEAPDSPKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-12-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q942</accession>
    <name>D3Q942_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Proton-translocating NADH-quinone oxidoreductase, chain M</fullName>
            <ecNumber evidence="7">1.6.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_0940</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Membrane</location>
            <topology evidence="1 3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I subunit 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="7"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_0940"/>
    <dbReference type="EnsemblBacteria" id="ADD40651">
        <property type="protein sequence ID" value="ADD40651"/>
        <property type="gene ID" value="Snas_0940"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_0940"/>
    <dbReference type="eggNOG" id="COG1008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007100_4_0_11"/>
    <dbReference type="OMA" id="GHMGFVL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010227">
        <property type="entry name" value="NADH_Q_OxRdtase_chainM/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43507">
        <property type="entry name" value="PTHR43507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01972">
        <property type="entry name" value="NDH_I_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049661" evidence="5">
        <location>
            <begin position="19"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="6">
        <location>
            <begin position="129"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD40651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="493" mass="50302" checksum="0E71937B64D1E77F" modified="2010-04-20" version="1">MKAVLVAVIALPALGALAAMAGRRSGERFAKWIAVGFAAAGLVAAAVLPLGAGDGPMWHRLNLPWAETIGLRFDLGVDGVSYPLIVLTALLTLLCCVHTLLYEPERGRGGVLSALLLVVAAGIIGVFTAANLVAFFVFFELVLLPMWAIIHWWGGPKRQHAALKFALYTLLGSLLLLAGIFVVGGTSGTGDLVALTEGAAAKLPAGTQLLAFALLTLGFAVKAPLWPLHTWLPDAHTEAPTVGSVILAGVLLKMGTYGMVRVSLGVAPDGAAQAAPVLGVLAVAAILIGGLVCLAQTELKRLIAYSSVGHMGFVVLGIATGTASGINAALYGNIAHGLITGLLFFLAGAVKDRTHSGELARLGGLRNVAPGLAGVLGFTALASLGLPGLAGFWGEAFAVYGSVTAAKPLWIVLAVLAACGAALAAVYLLRLLRLVTHGPSSPFIAGLGPAAALKRGEIAVWAPIIAGIVVFGLAPWLLLDTFASPLLEAVIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9C9</accession>
    <name>D3Q9C9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_2936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD42611">
        <property type="protein sequence ID" value="ADD42611"/>
        <property type="gene ID" value="Snas_2936"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_2936"/>
    <dbReference type="HOGENOM" id="CLU_1915809_0_0_11"/>
    <dbReference type="OrthoDB" id="1871372at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="132" mass="13035" checksum="57DBF261B309BA1C" modified="2010-04-20" version="1">MLAVSLAACSGAEEGSSSDNENAASKAAASAKDGTDYDACGDGRCEVAVSKKVEFKVDGGETKKKISVTDISTKEVAVECTFGSAGNGGEVSAVVAAGKESALGCQDLDVRISDVADGTAVLTLSPGDNPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D3Q9X5</accession>
    <name>D3Q9X5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_5034</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020242.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5034"/>
    <dbReference type="EnsemblBacteria" id="ADD44671">
        <property type="protein sequence ID" value="ADD44671"/>
        <property type="gene ID" value="Snas_5034"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5034"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="GEIQLIC"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD44671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="346" mass="37113" checksum="4FD54FEA9EFE7569" modified="2010-04-20" version="1">MSPAVEIAGLRKRYSSIFRPNTMALDGLDMVVEKGQVHGFLGPNGSGKTTTLRILLGLARANGGYMRILGHEVPRELPQVIQRVGSVVESPQFFKHFSGHKTLSLLAKTAGIPNSRVLEVLAQVGLHDRAKQKVKAYSLGMRQRLAVASALLKQPELLILDEPANGMDPAGIREMRELMQSLAAQGMTVLVSSHLLSEVQQLCDTMTIVSRGRRVTSGGVDEVIGRHGVGELRVRVGDDEQLSAAAQALETEDVTVTPATDHLMVSGVSDPAWVTKTLADEEIYVSELVRNAPDLETVFLQLTGTAPVDGRYPQVDDAVLPALPTQATAPAAETVTVTADSEESAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3QA95</accession>
    <name>D3QA95_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Snas_1097</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016378.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1097"/>
    <dbReference type="EnsemblBacteria" id="ADD40807">
        <property type="protein sequence ID" value="ADD40807"/>
        <property type="gene ID" value="Snas_1097"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1097"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_873278_0_0_11"/>
    <dbReference type="OMA" id="LDWHGVR"/>
    <dbReference type="OrthoDB" id="1308416at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="5">
        <location>
            <begin position="4"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Nudix hydrolase" evidence="5">
        <location>
            <begin position="161"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="132"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ADD40807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="305" mass="33504" checksum="87E81FBA05C58180" modified="2010-04-20" version="1">MQPKFRIAAYGVVWDDEGRILLARGSAKAEDPGWWFLPGGGVEHGEHPRDAVVREFAEETGLTIEVDKPLDTMSAVSTKGVHNNAVIFNVQITGGTLRPEADGTTDHCEWVRPEDVKGQAMTPFVAAVLGFGTPRPEQQYKKTEQHPRPTPPRRAKRGRKRRGQRFGAYGLTTDDRGRVLLARISDGYPGAGCWHLPGGGVDYGEQPREALLREIAEETGQSAEVVELLDVTSFRHRRAIGPEGYPLDWHGVRAIYRARVPEPSKARVVETAGGSTSESRWWDRDKVAGLKVSAALGDALRIAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAQ7</accession>
    <name>D3QAQ7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020274.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5067"/>
    <dbReference type="EnsemblBacteria" id="ADD44703">
        <property type="protein sequence ID" value="ADD44703"/>
        <property type="gene ID" value="Snas_5067"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5067"/>
    <dbReference type="eggNOG" id="COG5006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_1_1_11"/>
    <dbReference type="OMA" id="GVQAFYF"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="9"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="152"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="310" mass="31999" checksum="747D7EBFF8D5099E" modified="2010-04-20" version="1">MSTRSDAVKGVILIIAASAFFGVSGPFAKALFGTGLTPVQVTWLRLTGSAIVLVAAALPLLRQVRRLPFWGLIAFGLTAIAGVQAFYFLAVSRIPVGIALLLEFMGPVVVVAWIRFVRRTRLPRTAVIGTLLSVAGLAVVVEIWTGLRLDTLGLLAGAAAAACQAGYFLGGEKLTEQVNVRVLLAFGFVIGSLTLAPLAAPWSMDWGFLAENTTLAGTDVPAALTLAGLVVSTALAYATGLPALRLLSAPIAGGMAYAEVVVAALAAWLLLGEALTLPQVIGGAIVIAGVFTAQRAVSTRVTEPEPITAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3QAT0</accession>
    <name>D3QAT0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_5090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020297.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5090"/>
    <dbReference type="EnsemblBacteria" id="ADD44726">
        <property type="protein sequence ID" value="ADD44726"/>
        <property type="gene ID" value="Snas_5090"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5090"/>
    <dbReference type="eggNOG" id="ENOG5030DSB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090342_1_0_11"/>
    <dbReference type="OMA" id="ITHTIMI"/>
    <dbReference type="OrthoDB" id="1864489at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025333">
        <property type="entry name" value="DUF4239"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14023">
        <property type="entry name" value="DUF4239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD44726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="256" mass="27930" checksum="3D84E9D78C2AD794" modified="2010-04-20" version="1">MNPLLLGLLIVVGASILAGGVVMLQQRFSPPQDREGYNEVAGSVFEIISVLYAIVLAFVLIAVWEQRSEAREVTYDESNALVDVYWASKDLPKEQSGNLQNLCLDYANWVVDDEWPKMADREDVDDGGWKIIDAMYSEIDAGIPKKDETSIGLSQGAEEALASLSQARNERLNANDEGLTGVMWLVLVAGALLIFGILLLFGVPGRLAHVVVVVIAAAMVVLLLFSVFELEYPFSRGIALGTEPFDLALERMKAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3QB42</accession>
    <name>D3QB42_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative GAF sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1149"/>
    <dbReference type="EnsemblBacteria" id="ADD40859">
        <property type="protein sequence ID" value="ADD40859"/>
        <property type="gene ID" value="Snas_1149"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1149"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096802_2_0_11"/>
    <dbReference type="OMA" id="DCERVDR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="43"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD40859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="193" mass="21265" checksum="B886990B0B23F3CA" modified="2010-04-20" version="1">MTLMAFEATSRLITAPPDPHGRERAMRLRQLGVGLGQREDPRFDEFARRLAQIAGAPIGGVNFIDETQQYFAGMYAPTGDPDNAAAAPLRPEDPSRIMDREQGYCPHVVVRGKALVLEDVCDYPRFAGDPSVDDMGVRSYMAAPLIDRTGTVLGTVCAADVDIHPWGRRGLEIIKTMAAEVVDYVHRREGLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBD7</accession>
    <name>D3QBD7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018390.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3148"/>
    <dbReference type="EnsemblBacteria" id="ADD42819">
        <property type="protein sequence ID" value="ADD42819"/>
        <property type="gene ID" value="Snas_3148"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3148"/>
    <dbReference type="eggNOG" id="COG1426">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118048_0_0_11"/>
    <dbReference type="OMA" id="QGRWKAV"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16837">
        <property type="entry name" value="BldD_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038099">
        <property type="entry name" value="BldD-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037664">
        <property type="entry name" value="BldD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="15"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="168" mass="18384" checksum="58782FCBC38B5BE7" modified="2010-04-20" version="1">MASTPEYAKFLGNRLRDIRIQQGLSLQGVEDKSGGKWKAVVIGSYERGDRAITVARLSELATFYRVPVAELLPDGAPLPIEPGSKLTLDLAALYDHSSPDLAHVARYARGIQQRRGDYNGRILSIRADDLTALAIIYDTTPSDLIEKLSDLGVLIADPAKFFAEQDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBQ4</accession>
    <name>D3QBQ4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018507.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3266"/>
    <dbReference type="EnsemblBacteria" id="ADD42936">
        <property type="protein sequence ID" value="ADD42936"/>
        <property type="gene ID" value="Snas_3266"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3266"/>
    <dbReference type="eggNOG" id="COG3542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088365_0_3_11"/>
    <dbReference type="OMA" id="ERSHWHR"/>
    <dbReference type="OrthoDB" id="1565693at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06121">
        <property type="entry name" value="cupin_YML079wp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009327">
        <property type="entry name" value="Cupin_DUF985"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039935">
        <property type="entry name" value="YML079W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33387">
        <property type="entry name" value="PTHR33387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06172">
        <property type="entry name" value="Cupin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_5" evidence="1">
        <location>
            <begin position="9"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD42936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="147" mass="16205" checksum="9A0CCBA8AC582561" modified="2010-04-20" version="1">MVEQTSRSKLVDELDLAPHPEGGWFRETWAAPVGFEPDGYPGRRSAATAIYFLLHPGEESRWHTVRSDELWLWHQGGPLELRLGGDGDRPLADFTPVTLGMDVAAGQRPQQLVPGNVWQAAIPLGDEPTLVSCVVAPGFDMADFRMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBR6</accession>
    <name>D3QBR6_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase</fullName>
            <ecNumber evidence="1">3.5.1.118</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gamma-glutamyl hercynylcysteine S-oxide hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">egtC</name>
        <name evidence="3" type="ordered locus">Snas_5170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>gamma-L-glutamyl-hercynylcysteine S-oxide + H2O = L-glutamate + S-(hercyn-2-yl)-L-cysteine S-oxide</text>
            <dbReference type="Rhea" id="RHEA:42684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:82703"/>
            <dbReference type="ChEBI" id="CHEBI:82706"/>
            <dbReference type="EC" id="3.5.1.118"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; ergothioneine biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.118" evidence="1"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020376.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5170"/>
    <dbReference type="EnsemblBacteria" id="ADD44805">
        <property type="protein sequence ID" value="ADD44805"/>
        <property type="gene ID" value="Snas_5170"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5170"/>
    <dbReference type="eggNOG" id="COG0121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042555_3_0_11"/>
    <dbReference type="OMA" id="FSHNGAV"/>
    <dbReference type="OrthoDB" id="693464at2"/>
    <dbReference type="UniPathway" id="UPA01014"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052699">
        <property type="term" value="P:ergothioneine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02036">
        <property type="entry name" value="EgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017808">
        <property type="entry name" value="EgtC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026869">
        <property type="entry name" value="EgtC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032889">
        <property type="entry name" value="EgtC_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13230">
        <property type="entry name" value="GATase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03442">
        <property type="entry name" value="TIGR03442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="2">
        <location>
            <begin position="2"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="245" mass="26763" checksum="FC38735AD999A83B" modified="2010-04-20" version="1">MCRHLLYLGEPQRLSRPLFESPHSLCHQAYQPTDMRKGGTINADGFGVGWYAGDTALRYRRSTPIWSDTDLRHLADNTVASAFLAAIRSATVGMPVTQGASAPFTDGRWLFSLNGRIEGWPHSVAKQASALPVTELMTADAPTDAAFLWTLLRHRLRDNDPVETVRDLVGELAADAPGSRLNLLLTDGTRAIATTWWHALSVRRDPSGVTIASEPLDADAAWQPIGDRQLVTATASEVDISDLHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBV4</accession>
    <name>D3QBV4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_5208</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020414.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5208"/>
    <dbReference type="EnsemblBacteria" id="ADD44843">
        <property type="protein sequence ID" value="ADD44843"/>
        <property type="gene ID" value="Snas_5208"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5208"/>
    <dbReference type="eggNOG" id="ENOG5033NB7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_745791_0_0_11"/>
    <dbReference type="OrthoDB" id="1936369at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003048425" evidence="3">
        <location>
            <begin position="28"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD44843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="371" mass="38963" checksum="61C7BEDCF67ECDBD" modified="2010-04-20" version="1">MRKSLPRSLIAVGVVVAVFAFPSAAWADPGEDKKEKKDHPVSQAEADDPVVEPEVEPAPEVVEEPVPELPVEEPEIVEEPAPVEEPEVVEEPEVIEPATETEETEAAEETDEAKEAEEAEAELEEGESEIPINPGNVGTTAADFGPPNCDHIPGGMAPEGQDGWVFVLPGNDAAFVSVSATFAEDGTIAGTVVEGHDGKFAYVLANAGWTLTGATAVITGSTPQDQFNLTHACPGTSVPPPPCEDGSNPPCEEEPPPPCDDGREPPCEEEPPPPCDDGREPPCEEEPPPPDDEEPPDDEDTPPVTMHPPTEPTLEEFAPQGSSDRDGLAITGNSLGMLLLIGTILLTAGGAALILYRVANRARRLGGDVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBV5</accession>
    <name>D3QBV5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5209</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020415.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5209"/>
    <dbReference type="EnsemblBacteria" id="ADD44844">
        <property type="protein sequence ID" value="ADD44844"/>
        <property type="gene ID" value="Snas_5209"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5209"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_4_0_11"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="137" mass="14297" checksum="20D939101838C421" modified="2010-04-20" version="1">MTTDSVRNFSTDDLHPTGGYEHVTIVEPGRYANLAGQCPVDADEKVVGLGDIDRQIDQVAANALAAITAAGARPEDVVRSVVYVVSADSAVVGAAWHRFAENTVLAPAFKAASTVLGVTALGYSGQLVELDLTVRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D3QBX0</accession>
    <name>D3QBX0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020430.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5225"/>
    <dbReference type="EnsemblBacteria" id="ADD44859">
        <property type="protein sequence ID" value="ADD44859"/>
        <property type="gene ID" value="Snas_5225"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5225"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="GKQPELC"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD44859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="316" mass="34650" checksum="DBA2940C9ECBE55F" modified="2010-04-20" version="1">MQLPQLKSFVTVCDTRHFTRAAELLHVAQPSLSQQIKALEHELGTPLFRRARGNITPTDAGAALLPVARRILADTELAYREVADTVDLRRGRVRLGAPPSLCASLVPDIFRVFHDRYPGVELTVDEGGSQDLVRTLTDGELDLALIITHQTGRPAALRVAELLHENLVVASAPQLPPPGKRARITVADLRDQPLVMFRRGYDLRESTITACREAGFEPTFTVEGGEMDAVLGFVRAGLGLAVVPSMVAERSGLRITRFTRSGPERTIAIAHRRDVQPPRAARELHRMLLEHLRSADANGELPPETTLLAEAFAPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D3PU48</accession>
    <name>D3PU48_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Proton-translocating NADH-quinone oxidoreductase, chain L</fullName>
            <ecNumber evidence="9">1.6.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Snas_1285</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="9"/>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD40994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016565.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1285"/>
    <dbReference type="EnsemblBacteria" id="ADD40994">
        <property type="protein sequence ID" value="ADD40994"/>
        <property type="gene ID" value="Snas_1285"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1285"/>
    <dbReference type="eggNOG" id="COG1009">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007100_6_0_11"/>
    <dbReference type="OMA" id="LIGFWQH"/>
    <dbReference type="OrthoDB" id="1274678at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018393">
        <property type="entry name" value="NADHpl_OxRdtase_5_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003945">
        <property type="entry name" value="NU5C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42829">
        <property type="entry name" value="PTHR42829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01974">
        <property type="entry name" value="NDH_I_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="513"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="614"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_N" evidence="8">
        <location>
            <begin position="78"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="7">
        <location>
            <begin position="145"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ADD40994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="635" mass="67737" checksum="9608C8B29C12237A" modified="2010-04-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUA7</accession>
    <name>D3PUA7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HPr kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016624.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1345"/>
    <dbReference type="EnsemblBacteria" id="ADD41053">
        <property type="protein sequence ID" value="ADD41053"/>
        <property type="gene ID" value="Snas_1345"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1345"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_591393_0_0_11"/>
    <dbReference type="OMA" id="MDICERC"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="143"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="473" mass="51803" checksum="A029B7D73AAD64D6" modified="2010-04-20" version="1">MTAPTAEPDPIDCRSIDDVVAYLAGLKVWARDMSFREITKRINEHRKKSRIPEPAKLATVNDCFKTGRRRLNWDLVIDIGRALGLSQAGVTRLEQVCRLITARIEQSDVADVRDSIPTGRPEFTGRKNEGQLILDGLQEAVRSQRPGVAIIHGPAGVGKTELALQLAHHVIREGYCADVQLFADLHGFDAQRPACSADAVLSGFLRLLGRTSADIATLPSVEQKAARFRHLLTGKATLLIVDNVPGPESLAPLLPGLASTLVLVTSRNRDGWPGLAAQLALQPLSVDEGMTLLRRFDVGDRVDAEPEAAGLLVDRLCSGLPLDLVALGGQLADPAESTWTLSDHAARLQRFPRDQVQRPALAGSCQGLSPDARRAFRLLALLPRDDFTVHETAILSDIEHAEAEQALAELFNRHLLLRRHAGRYRFHDAVAEFARHLLYQEEPASAQHAALARLRNATTKVVTMRRAPVPPPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUH7</accession>
    <name>D3PUH7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3324</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD42990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018561.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3324"/>
    <dbReference type="EnsemblBacteria" id="ADD42990">
        <property type="protein sequence ID" value="ADD42990"/>
        <property type="gene ID" value="Snas_3324"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3324"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="GFQHILN"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD42990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="219" mass="23648" checksum="D8B667CD63FC790B" modified="2010-04-20" version="1">MIRVLVVDDEALIRTGFTHILNAPDDITVVAAVPGGQAVDATVQHRPDVVLLDIRMPDVDGLTILRQLRGLTRPPVVAMLTTFDTDEYVAAALRLGAAGFLLKDTDPEHLAHQVRALMSDGAVLSAKVTRSVVDGYLQGENRGQHTTRVSRLTRREREVLVLIAEGMSNSDIAARMFLSVGTVKDHVSAILTKLGINNRVQAALLAERAGILPPPGDDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D3PUV4</accession>
    <name>D3PUV4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD44978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5344"/>
    <dbReference type="EnsemblBacteria" id="ADD44978">
        <property type="protein sequence ID" value="ADD44978"/>
        <property type="gene ID" value="Snas_5344"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5344"/>
    <dbReference type="eggNOG" id="COG2367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077675_0_0_11"/>
    <dbReference type="OMA" id="SWALMDR"/>
    <dbReference type="OrthoDB" id="1158151at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD44978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="281" mass="30418" checksum="99456C8F69ADB58E" modified="2010-04-20" version="1">MTRRFITFGIITTALVAFGAAFGIHAFSDTLLQTTSGNSKTLTIAPEGDTDVDVDIDGFANWALLDRSSGDIEGANLKETSTPQSMIKPWLVADYLRQAESDAPPLLDSASAAIRISDDEAAQTIYEELGEDASIERLISTCALTDTTVFPGRWSKTEMSVRDAARMGECVADGRAAGPWTKWLLNEMRHVRGSTADEDQHATSGGGRWGIIDGLPASLRDEVAIKNGWTRMADGDWDLNCLAIHDDWVLAIMMGYSGDRSLDYGADRCRAITEQLFGSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV51</accession>
    <name>D3PV51_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD41104">
        <property type="protein sequence ID" value="ADD41104"/>
        <property type="gene ID" value="Snas_1397"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1397"/>
    <dbReference type="eggNOG" id="COG3568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1651093_0_0_11"/>
    <dbReference type="OrthoDB" id="1387978at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="160" mass="18165" checksum="EF8EBB5481D212A6" modified="2010-04-20" version="1">MVKAEQPTILGTQEGRGNQIRDLKDRLPGYWWAWRGREKDGSGETCAAFYRKDRLEKLDEGHRWLSTTPTVPGSISWGAKTMIDGSFHDSWNHKAARVTPTYGTANGWRPRPKPDGRRIDWIIATERFAVHKAGINTWVTRHDNLCSDHWAVQAVVSLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D3PV68</accession>
    <name>D3PV68_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_1414</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1414"/>
    <dbReference type="EnsemblBacteria" id="ADD41121">
        <property type="protein sequence ID" value="ADD41121"/>
        <property type="gene ID" value="Snas_1414"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1414"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="ELFPYLM"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD41121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="238" mass="24772" checksum="975388E44F89B6C9" modified="2010-04-20" version="1">MTLLTLSGVHRTHGRGETAVRALRGVDMSVGPGELVAVMGPSGSGKSTLLNIAGGLDMPTSGEVSVDDTPLASLPKRALSRLRRRSIGYVFQNFNLVPSLTAIENVALPLELDGVPVRKARAAAAGSLADVGVGDLAERFPDDMSGGQQQRVAIARAVVGERRLVLADEPTGALDSRTGESVLRLLRARCDSGAGGVLVTHDARHAAWADRVVFLRDGRVVDAAGPLPSVDSLLEGTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVB5</accession>
    <name>D3PVB5_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FkbH like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1464</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1464"/>
    <dbReference type="EnsemblBacteria" id="ADD41168">
        <property type="protein sequence ID" value="ADD41168"/>
        <property type="gene ID" value="Snas_1464"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1464"/>
    <dbReference type="eggNOG" id="COG3882">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018095_0_0_11"/>
    <dbReference type="OMA" id="MYQAGFR"/>
    <dbReference type="OrthoDB" id="1310135at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010037">
        <property type="entry name" value="FkbH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01686">
        <property type="entry name" value="FkbH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="340" mass="37386" checksum="CF252C73780661E9" modified="2010-04-20" version="1">MIKCVVWDLDRTLVDGVFLESDDLRPRDGVLAVLRTLHGRGIVNSIASRNPPGSASTVLDGLGLGVSFVYPQFGWGVKSDSIRRIADKLRIGLDTFAFVDDDPYERTEVAAALPEVLVLSPDDIAGALDWPEFSPATVTPEARRRAESYQEAQERERVSREFTGSKEAFQRYCRTEITIRPATTADVPRLAELSRRTSRFNSRTTALSETEFADRLNSSEHTVVCVNLRDRFGDDGIIGGVVVARGSAWEAELVMMSCRAMGRGVIEAVLSWLGGATRAADARFVWVPLRVNERNLPLRLALIAAGYRAEATREGDAIFTHEVSEADGELAAWVKVDTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVH9</accession>
    <name>D3PVH9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3429"/>
    <dbReference type="EnsemblBacteria" id="ADD43093">
        <property type="protein sequence ID" value="ADD43093"/>
        <property type="gene ID" value="Snas_3429"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3429"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_3_2_11"/>
    <dbReference type="OMA" id="NDRRECP"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="108" mass="11878" checksum="01EE460B57709CFA" modified="2010-04-20" version="1">MSNQCVLMSSIHVDVIRLLSDPLRRHIVELLAQGPACTCHLVTDTGAKQPAVSHHLKVLKEAGLVASEPHGRYTYYRLLPDALETTAHGLTALVQSARRSANDRRECP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVJ1</accession>
    <name>D3PVJ1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3441"/>
    <dbReference type="EnsemblBacteria" id="ADD43105">
        <property type="protein sequence ID" value="ADD43105"/>
        <property type="gene ID" value="Snas_3441"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3441"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_2_3_11"/>
    <dbReference type="OMA" id="HALHIDN"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="143"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="271" mass="28915" checksum="7036AD932BC48064" modified="2010-04-20" version="1">MVVGVDGSPESVEAVDIAAVEAEVYQTNLRIVHVRTPSETATVIRSRPRDGERPRDGTRVLAEARRRVEDRHPGMTVEEHLADGDAATILIEESAHARLLVVGARGLGGFTGLLLGSTAVRVATLATCPVMVVRGGTHRSGPVVVGLDDPATSAAVSAFASREAERRRVALHALHIDNRGPSMEEHSTSDIDVADRLSAWSRRWCDEFPDVEVSVTVVSGVEPADALTEASRSAGVVVIGSRCRFGSKMLGSTAYALVHRCDCPLVLVNDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PVY4</accession>
    <name>D3PVY4_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_5474</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020676.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5474"/>
    <dbReference type="EnsemblBacteria" id="ADD45105">
        <property type="protein sequence ID" value="ADD45105"/>
        <property type="gene ID" value="Snas_5474"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5474"/>
    <dbReference type="eggNOG" id="COG0406">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_9_5_11"/>
    <dbReference type="OMA" id="WQVRQTA"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD45105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="198" mass="22049" checksum="2FA1D5E7AB1AB70B" modified="2010-04-20" version="1">MKRLIVLRHGQTAWNDENRVQGSVDIDLNEAGRAQAGEAAKVLARLTPSVVVASDMRRAVDTAQLVADLVGLDVRIDKRLRERAYGPWEGLTRAQIAERFPEAFELWRARKPFELEDMEVLSEVADRTAAALSEVAAEPGDGTAVVVTHGGSSRQGIVRFLGWSQEQANTMFGMENCHWADLRLEHTGWRMYGYNLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D3PW70</accession>
    <name>D3PW70_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipolytic protein G-D-S-L family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_1523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016798.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1523"/>
    <dbReference type="EnsemblBacteria" id="ADD41227">
        <property type="protein sequence ID" value="ADD41227"/>
        <property type="gene ID" value="Snas_1523"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1523"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051989_5_2_11"/>
    <dbReference type="OMA" id="NDTWRRY"/>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="14"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD41227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="220" mass="24269" checksum="8224152B3BA3452B" modified="2010-04-20" version="1">MTITLRPGSTVMFTGDSITDCRRHDSEDGLGFGYPLRVAGAWALRHPDRPVTWLNTASGGHKVMDLETRWRSDVLDARPDVVSILVGINDVGWHSYDPNGHVIPVEDFAAGYDRLLAPLAESGADLILIEPFLLPIRGVIEVGPVRLDETDREKWRTDLDPKIQVVRDLARRYDAHLLTADSMFTELTATTGPEYWAADGVHPTPAGHAALATAWLRLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWM7</accession>
    <name>D3PWM7_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43249">
        <property type="protein sequence ID" value="ADD43249"/>
        <property type="gene ID" value="Snas_3588"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3588"/>
    <dbReference type="HOGENOM" id="CLU_2425499_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="91" mass="9743" checksum="45CF92E218624DC8" modified="2010-04-20" version="1">MANPVTDPDVSNTSGPARFATVLVNDPGRFKKLSFSRQLVRVNGFVGIVKRLQVSIVFIMVRVNGIMVTLMAFTVTIGGAARVSPSFEGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWS0</accession>
    <name>D3PWS0_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3632</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3632"/>
    <dbReference type="EnsemblBacteria" id="ADD43292">
        <property type="protein sequence ID" value="ADD43292"/>
        <property type="gene ID" value="Snas_3632"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3632"/>
    <dbReference type="HOGENOM" id="CLU_1389479_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="112"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="196" mass="21238" checksum="6B8DC200048E28C1" modified="2010-04-20" version="1">MHDPQHSNHHYPPTNVPSSPGTGPSGTPPYPPPMATPTPGFRTVDRLGPGTRGYTLPPEQPPGSPPPETGFARLPSFGNRKRLLPLLAGLVALFVITSAVFIILFFHTRSDLTAAKATITKHEATINDADKKIKKLGGSNDDLEDDVEEAEADSKAARECIDAFQAWLDEATKKKPDKSTVKDLADKANTACREFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2020-08-12" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D3PWS1</accession>
    <name>D3PWS1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_3634</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD43293">
        <property type="protein sequence ID" value="ADD43293"/>
        <property type="gene ID" value="Snas_3634"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3634"/>
    <dbReference type="HOGENOM" id="CLU_3173445_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD43293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="47" mass="4998" checksum="ACF3E18CCC62AE52" modified="2010-04-20" version="1">MEHNAQRIAIAAAAQARGLIQRSLTHDVPIDARLLTESCAALATLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXE1</accession>
    <name>D3PXE1_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Snas_1705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013016975.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1705"/>
    <dbReference type="EnsemblBacteria" id="ADD41404">
        <property type="protein sequence ID" value="ADD41404"/>
        <property type="gene ID" value="Snas_1705"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1705"/>
    <dbReference type="eggNOG" id="COG3705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_908783_0_0_11"/>
    <dbReference type="OMA" id="GFVDWTQ"/>
    <dbReference type="OrthoDB" id="1630212at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ADD41404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="318" mass="34400" checksum="544B81D8C91EA13C" modified="2010-04-20" version="1">MESGHLARIERAAGVDGLTDILSDRLSPSDLRSLLLEVHRRRAAAVTPAQLLRQYQRDRFSEPSDLSLDDLHALDALVLPRLAASGYEAVALSPVCPLGTNSVVSTVPQNNVVTTGRGTEVIADATNVLALECATRRQSAAGSTDVVRLAASQRVVRGQPIQGRGLSPHFKLLALCTAGRDTGGFGFETTALTEQLTIQLRLLESMARDGYHLNDVEVSLTDLNGGTRKPVLDSRVFAPLAEAFPEVRFGYDDDRTSGTNYYTDVSLAVSARDARGERITFSDGGFTTWTRQLLGNAKERLLIGGLGLELTHRLFRDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXK3</accession>
    <name>D3PXK3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Snas_3676</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018904.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3676"/>
    <dbReference type="EnsemblBacteria" id="ADD43333">
        <property type="protein sequence ID" value="ADD43333"/>
        <property type="gene ID" value="Snas_3676"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3676"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="HITALMT"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ADD43333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="214" mass="22729" checksum="86837DBDC61949A2" modified="2010-04-20" version="1">MIRVLLVDDQRLIRAGLRMLCEPAADIEVVGEADGGQAAVRLAGELCPDLVLMDLRMPGMDGITATQRILAERPSTRVVALTTFDDDDHLYPALAAGACGFLVKDTSPNELLEAIRKAADGDTPFSAGVVKRIVDSAVRARASVPTATLPKLTTREREVLALVGAGYANVDIAERLHLGVTTVKTHIASLMTKTGCSNRVRLAVLAVRSGTTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXN8</accession>
    <name>D3PXN8_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018939.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3711"/>
    <dbReference type="EnsemblBacteria" id="ADD43368">
        <property type="protein sequence ID" value="ADD43368"/>
        <property type="gene ID" value="Snas_3711"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3711"/>
    <dbReference type="eggNOG" id="COG5563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_737521_0_0_11"/>
    <dbReference type="OrthoDB" id="816743at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ADD43368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="375" mass="40612" checksum="10FCCA79E2B13972" modified="2010-04-20" version="1">MANPIGKRWWLVGGVTALVVALVAVTLTIIGHVSDGAIYDPSDPKTDTRTIAPLAKDCDFDMLDWEQSKSGDVLDFKMSPNGEYIAMNDPNNSDIHLWHNGKRKALPPPPKGSYTGMADLNNDGVVIGSGTDEDDIDSYMWKFEDGKVRILTAKGKWTGGTPSAIADDGTIIGPEPSSNTGYRDELLKWEPGETEATTLKLKAEGEDKAPSVSDIADDGTLVGGLLDADVMEAAGLEDYEPRLWTPDGRYEDIAVEGEDDDGALARNISGDWILVTTYSSSYRWKRTADHQPEKVKGIEALAIDDSGRMYGATGKGKQRVPAVFDTEIRQLPVPKDVPNLIPKNSYGYSTVSAASQDGSVLVGNWKGNPVMWTCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXP2</accession>
    <name>D3PXP2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_3715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013018943.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3715"/>
    <dbReference type="EnsemblBacteria" id="ADD43372">
        <property type="protein sequence ID" value="ADD43372"/>
        <property type="gene ID" value="Snas_3715"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3715"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="RKHADGA"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="168"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD43372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="374" mass="39893" checksum="DEF69C7BA07FD79F" modified="2010-04-20" version="1">MRSEVGRRWPGWDDVLLTLVVGYMTVEEVYLRSGPLVVVEVTLAAVASLVLLWRHRWPMPSAVLAVAAAILLGAALPLVVMLFHLAYANRLITSVIAAIVAVGGNLPMDAQHSLFAPRDPGPVLLLVLPLALGMWAGGRRRLVAALEDQVTRLRTERELRAERARMAERAQIAAEMHDVLAHRLSVLALHTGALQRRAATLPEQVATRIDLLRATSTDALDDLRDMLGALRNPTRDTETAALTPVDSGLPNLLDEARAAGQTVDAVVEGDPDAAPASHRLAVLRLVQEGLTNARKHADGATARVEVHYGAPATTVRVDNDPAATGSEAGGGYGLIGLAERISALRGTIEYGHGPSGGWYLTARIPLPAHTVTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXV2</accession>
    <name>D3PXV2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver and ANTAR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Snas_3775</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019003.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3775"/>
    <dbReference type="EnsemblBacteria" id="ADD43432">
        <property type="protein sequence ID" value="ADD43432"/>
        <property type="gene ID" value="Snas_3775"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3775"/>
    <dbReference type="eggNOG" id="COG3707">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_65_0_11"/>
    <dbReference type="OMA" id="QKTSMDR"/>
    <dbReference type="OrthoDB" id="1958442at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005561">
        <property type="entry name" value="ANTAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008327">
        <property type="entry name" value="Sig_transdc_resp-reg_antiterm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03861">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036382">
        <property type="entry name" value="RR_antiterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01012">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50921">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="12"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="ANTAR" evidence="3">
        <location>
            <begin position="132"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ADD43432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="207" mass="22811" checksum="DCD7782B6021E924" modified="2010-04-20" version="1">MTGTDAEAAPRRVLIAEDEGLIRLDLAEMLAEEGFEVVGEAADGETAVKLAEEKRPDLVICDIQMPIMDGLQAAERIVAARIAPVVILTAFSQRDLIARANSAGAMAYLVKPFQKSDLVPAIELSLARFAELTALEAEVESLTERLEIRKLVDRAKGLLMTRYGMAEPDAFRWIQRAAMDHRLSMRDVAMRIIEESQPSESDELSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D3PXY3</accession>
    <name>D3PXY3_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5682</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_5682"/>
    <dbReference type="EnsemblBacteria" id="ADD45312">
        <property type="protein sequence ID" value="ADD45312"/>
        <property type="gene ID" value="Snas_5682"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5682"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056943_2_0_11"/>
    <dbReference type="OMA" id="WETEMAL"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="272"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="341" mass="36537" checksum="D5E94642894F3C7E" modified="2010-04-20" version="1">MGIPKLMDHSGIMSTMPRSWQRLLDGVGLTAAAERVYRAILADPRASPATLAEAAAVDAAALPELCELLRGLGLIDTEDDGTARPVDPRIGMSALLRRQQDGIERAVAAVTDLTDDFLDGQTRIGASPLTELVRGRHHLETTIRALITSARSEVAVLDTPPYAAANSIEPAEEFSLESGVSNRAIYAAEVLENPELYDNIRKMTAAGEQARMLPEVPLKLLVVDGSRALLPITLEGDVSNSAVLVHPSALTTALTALFEALWAKALPIFDPVGATHGPLDPEERELLGMLASGVKDEAIARRLGISNRTVSRRVNRLLERLGAANRFQAGLQAARQGWLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D3PY04</accession>
    <name>D3PY04_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_5703</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD45333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013020904.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ADD45333">
        <property type="protein sequence ID" value="ADD45333"/>
        <property type="gene ID" value="Snas_5703"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_5703"/>
    <dbReference type="HOGENOM" id="CLU_1488186_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003049552" evidence="2">
        <location>
            <begin position="30"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD45333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="181" mass="19085" checksum="6BEE565D79C0ACE3" modified="2010-04-20" version="1">MKLIRISALVLTGAVAVALTACEPKEDSASSSGDKSSEASDQGGKDEDKEESGSGSSSSKDKLAGDVTTVTLTKSGGFAGNEETLEIDAEGKWSYVKAKMATKKGDLSSKELKQLIDLAGTKGITDTNKKSDKQCNDMPTFQLKVELSEGKPVEMKTDECGVAPNEEFDNLIELLTDATPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYI9</accession>
    <name>D3PYI9_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Snas_1860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD41556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_1860"/>
    <dbReference type="EnsemblBacteria" id="ADD41556">
        <property type="protein sequence ID" value="ADD41556"/>
        <property type="gene ID" value="Snas_1860"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_1860"/>
    <dbReference type="eggNOG" id="ENOG502ZN6T">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_826133_0_0_11"/>
    <dbReference type="OMA" id="GYLTWAR"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ADD41556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="336" mass="33987" checksum="940ED900F84B0E4F" modified="2010-04-20" version="1">MLSRRKGAHATDAGKVTPRTLTRVNATTTDRRSRPAGIVSLVLLAIAAAWLIVSFLSLRVLVAEVVKADSRAIATLITSMSGAVMGAVFGGTCAGHLARISRLGFLTRLPRLVTGAAAGVLVGVAAAGLAYYTFSGTPAVATIVAGVTGIAAIVGGCLAAPRNTDAVFAGLCGTVVVLVVMFARGWFAAEINSMMTPGSYQWVGIAFGVALGMLVGIAAVLVLRLRAPRTTLSGYLAAGAAPGALWLVSEVATRVAAGLLVAKGIEPDPISNLGMELILEAQLNGSLAALFTGGTTAVLAFGTLMSKGGNKKTGRGGKASVPSQTKATNTKSKAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYK4</accession>
    <name>D3PYK4_STANL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Snas_3780</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Chen F."/>
                <person name="Lucas S."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Chain P."/>
                <person name="Pitluck S."/>
                <person name="Goker M."/>
                <person name="Ovchinikova G."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304662"/>
            <dbReference type="DOI" id="10.4056/sigs.47643"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001778">
        <property type="protein sequence ID" value="ADD43437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_013019008.1">
        <property type="nucleotide sequence ID" value="NC_013947.1"/>
    </dbReference>
    <dbReference type="STRING" id="446470.Snas_3780"/>
    <dbReference type="EnsemblBacteria" id="ADD43437">
        <property type="protein sequence ID" value="ADD43437"/>
        <property type="gene ID" value="Snas_3780"/>
    </dbReference>
    <dbReference type="KEGG" id="sna:Snas_3780"/>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045498_1_1_11"/>
    <dbReference type="OMA" id="MTPILLW"/>
    <dbReference type="OrthoDB" id="1445898at2"/>
    <dbReference type="Proteomes" id="UP000000844">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="288"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ADD43437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000844"/>
        </source>
    </evidence>
    <sequence length="332" mass="33474" checksum="CCF7840EAAABBAED" modified="2010-04-20" version="1">MDISLLVIVAGVLVGLSVGLTGMGGGALMTPIMVLVFGVNPTAAVGSDLTASVAMKPVGAVVHHRAGTVRWDLVRWLLPTAIPAGFAGAWLISLLGDGKAVQDGLKLIIGAALLLAVVGMFARIILSRRRGTATTDGPTRIKPVPALLIGVVGGLIVGVTSVGSGSLIIVLLMLTHPRLRANELVGTDLVQAIPLVASAALGHWIFGDTQLALAGTVLLGAIPGIYVGAKLSARAPESILRWALAVLLLGSGMALWDVPGVVTLLACAALVGIAVAAHFIGRAGDREPVGLTGDDDAAEREPRPVATSRSAADGTAEAEPQPAATGTSTPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-04-20" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D3PYM2</accession>
    <name>D3PYM2_STANL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Snas_3799</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)</name>
        <dbReference type="NCBI Taxonomy" id="446470"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Glycomycetales</taxon>
            <taxon>Glycomycetaceae</taxon>
            <taxon>Stackebrandtia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="292" last="299">
            <title>Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21).</title>
            <authorList>
                <person name="Munk C."/>
                <person name="Lapidus A."/>
                <person name="Copeland A."/>
                <person name="Jando M."/>
                <person name="Mayilraj S."/>
              